#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P32561 uniprotkb:P53691 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-5429|uniprotkb:Q6Q5K7|uniprotkb:D6VYL7|ensemblfungi:YLR216C psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:ppid_yeast(display_long)|uniprotkb:CPR6(gene name)|psi-mi:CPR6(display_short)|uniprotkb:YLR216C(locus name)|uniprotkb:L8167.24(orf name)|uniprotkb:Rotamase CPR6(gene name synonym) psi-mi:"MI:0018"(two hybrid) Duina et al. (1996) pubmed:8873448 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1564453 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_013317.1|sgd:S000004206|dip:DIP-1274N|mint:P53691|ensemblfungi:YLR216C(gene)|ensemblfungi:YLR216C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0042026"(protein refolding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR020892|interpro:IPR029000|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6798695 - crc64:34FFD72A7E7425DB crc64:188666D94866DDDD - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/12/05 2014/10/16 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:SUaJi3kS2xpEcuxgMcms2Bm3/Eo559292 intact-crc:69B0E385BC489625|rigid:vbL9oZTVs0CrZL50ie14XVRNd9Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P32561 uniprotkb:P47103 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-5436|uniprotkb:Q92323|uniprotkb:D6VWK5|ensemblfungi:YJR032W psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:cyp7_yeast(display_long)|uniprotkb:CPR7(gene name)|psi-mi:CPR7(display_short)|uniprotkb:YJR032W(locus name)|uniprotkb:J1585(orf name)|uniprotkb:Rotamase CYP7(gene name synonym) psi-mi:"MI:0018"(two hybrid) Duina et al. (1996) pubmed:8873448 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1564457 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_012566.1|sgd:S000003793|dip:DIP-2312N|mint:P47103|ensemblfungi:YJR032W(gene)|ensemblfungi:YJR032W_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR020892|interpro:IPR029000|rcsb pdb:5JHE|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6798695 - crc64:34FFD72A7E7425DB crc64:1532F255E8016F4F - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/12/05 2014/10/16 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:XYsRUaaWVHJucY5c9n661bDnKoE559292 intact-crc:F56AF6A58F5A5678|rigid:OkYwmShQKEOkPOPsem6zC3srIHg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P32561 uniprotkb:P53691 intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C intact:EBI-5429|uniprotkb:Q6Q5K7|uniprotkb:D6VYL7|ensemblfungi:YLR216C psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:ppid_yeast(display_long)|uniprotkb:CPR6(gene name)|psi-mi:CPR6(display_short)|uniprotkb:YLR216C(locus name)|uniprotkb:L8167.24(orf name)|uniprotkb:Rotamase CPR6(gene name synonym) psi-mi:"MI:0096"(pull down) Duina et al. (1996) pubmed:8873448 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1564470 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 refseq:NP_013317.1|sgd:S000004206|dip:DIP-1274N|mint:P53691|ensemblfungi:YLR216C(gene)|ensemblfungi:YLR216C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0042026"(protein refolding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR020892|interpro:IPR029000|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6798695 - crc64:34FFD72A7E7425DB crc64:188666D94866DDDD figure legend:Fig. 2B taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/12/05 2014/10/16 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 rogid:SUaJi3kS2xpEcuxgMcms2Bm3/Eo559292 intact-crc:ECA7FA15131BABFD|rigid:vbL9oZTVs0CrZL50ie14XVRNd9Q false ha tag:c-c glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P47103 uniprotkb:P32561 intact:EBI-5436|uniprotkb:Q92323|uniprotkb:D6VWK5|ensemblfungi:YJR032W intact:EBI-15864|uniprotkb:D6W0L7|ensemblfungi:YNL330C psi-mi:cyp7_yeast(display_long)|uniprotkb:CPR7(gene name)|psi-mi:CPR7(display_short)|uniprotkb:YJR032W(locus name)|uniprotkb:J1585(orf name)|uniprotkb:Rotamase CYP7(gene name synonym) psi-mi:rpd3_yeast(display_long)|uniprotkb:RPD3(gene name)|psi-mi:RPD3(display_short)|uniprotkb:SDI2(gene name synonym)|uniprotkb:YNL330C(locus name)|uniprotkb:N0305(orf name)|uniprotkb:MOF6(gene name synonym)|uniprotkb:REC3(gene name synonym)|uniprotkb:SDS6(gene name synonym)|uniprotkb:Transcriptional regulatory protein RPD3(gene name synonym) psi-mi:"MI:0096"(pull down) Duina et al. (1996) pubmed:8873448 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1564479 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012566.1|sgd:S000003793|dip:DIP-2312N|mint:P47103|ensemblfungi:YJR032W(gene)|ensemblfungi:YJR032W_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR020892|interpro:IPR029000|rcsb pdb:5JHE|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6798695 ensemblfungi:YNL330C(gene)|ensemblfungi:YNL330C_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000117"(regulation of transcription involved in G2/M transition of mitotic cell cycle)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031939"(obsolete negative regulation of chromatin silencing at telomere)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032221"(Rpd3S/Clr6-CII complex)|go:"GO:0033698"(Rpd3L complex)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034503"(protein localization to nucleolar rDNA repeats)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0045128"(negative regulation of reciprocal meiotic recombination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051038"(negative regulation of transcription involved in meiotic cell cycle)|go:"GO:0061186"(negative regulation of silent mating-type cassette heterochromatin assembly)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|go:"GO:0070210"(Rpd3L-Expanded complex)|go:"GO:0070211"(Snt2C complex)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0070550"(rDNA condensation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|reactome:R-SCE-3214815|reactome:R-SCE-4551638|reactome:R-SCE-9018519|go:"GO:0070822"(Sin3-type complex)|go:"GO:0070932"(histone H3 deacetylation)|refseq:NP_014069.1|sgd:S000005274|dip:DIP-681N|mint:P32561 - crc64:1532F255E8016F4F crc64:34FFD72A7E7425DB figure legend:Fig. 2B taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/12/05 2014/10/16 rogid:XYsRUaaWVHJucY5c9n661bDnKoE559292 rogid:GQ1xB56fpHiVV03yhoPADv04fl0559292 intact-crc:A7061BE955346329|rigid:OkYwmShQKEOkPOPsem6zC3srIHg false glutathione s tranferase tag:?-? ha tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)