#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P25847	uniprotkb:P25336	intact:EBI-11352|uniprotkb:Q12423|ensemblfungi:YOL090W|uniprotkb:D6W1X8	intact:EBI-11362|ensemblfungi:YCR092C|uniprotkb:D6VR92	psi-mi:msh2_yeast(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:YOL090W(locus name)|uniprotkb:O0935(orf name)|uniprotkb:MutS protein homolog 2(gene name synonym)	psi-mi:msh3_yeast(display_long)|uniprotkb:MSH3(gene name)|psi-mi:MSH3(display_short)|uniprotkb:YCR092C(locus name)|uniprotkb:YCR92C(orf name)|uniprotkb:YCR1152(orf name)|uniprotkb:MutS protein homolog 3(gene name synonym)|uniprotkb:Mismatch-binding protein(gene name synonym)	psi-mi:"MI:0226"(ion exchange chromatography)	Habraken et al. (1996)	pubmed:8805366	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1368866	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YOL090W(gene)|ensemblfungi:YOL090W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000735"(removal of nonhomologous ends)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006312"(mitotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043111"(replication fork arrest)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|reactome:R-SCE-5358565|reactome:R-SCE-5358606|go:"GO:0032300"(mismatch repair complex)|refseq:NP_014551.1|sgd:S000005450|mint:P25847|dip:DIP-2415N	interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|reactome:R-SCE-5358606|ensemblfungi:YCR092C(gene)|ensemblfungi:YCR092C_mRNA(transcript)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0000735"(removal of nonhomologous ends)|go:"GO:0005737"(cytoplasm)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0032135"(DNA insertion or deletion binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0043111"(replication fork arrest)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|refseq:NP_010016.2|sgd:S000000688|mint:P25336|dip:DIP-2422N	-	crc64:43FFD8A640138AE4	crc64:1AD91C2E2F2856EF	figure legend:Figure 1|comment:Stoichiometry taken from densometric scans showing components to be present in equi-molar ratios.	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/07/12	2014/10/16	rogid:PNwekSiaI58qR+dPZZQW5UNRJ+4559292	rogid:+wUVIWkJoR5KHA7YuIYdskdQszE559292	intact-crc:C56CB7A95A9AB249|rigid:2BrF7CMlr2a13LhsmnSOlieH+MY	false	-	-	1	1	psi-mi:"MI:0816"(molecular weight estimation by staining)	psi-mi:"MI:0816"(molecular weight estimation by staining)
intact:EBI-1368872	uniprotkb:P25336	-	intact:EBI-11362|ensemblfungi:YCR092C|uniprotkb:D6VR92	psi-mi:msh2-msh3-binding(display_short)|psi-mi:EBI-1368872(display_long)	psi-mi:msh3_yeast(display_long)|uniprotkb:MSH3(gene name)|psi-mi:MSH3(display_short)|uniprotkb:YCR092C(locus name)|uniprotkb:YCR92C(orf name)|uniprotkb:YCR1152(orf name)|uniprotkb:MutS protein homolog 3(gene name synonym)|uniprotkb:Mismatch-binding protein(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Habraken et al. (1996)	pubmed:8805366	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1368880	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0681"(double stranded deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR017261(DNA mismatch repair protein Msh6)|interpro:IPR027417|interpro:IPR036187|interpro:IPR036678|reactome:R-SCE-5358606|ensemblfungi:YCR092C(gene)|ensemblfungi:YCR092C_mRNA(transcript)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0000735"(removal of nonhomologous ends)|go:"GO:0005737"(cytoplasm)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0032135"(DNA insertion or deletion binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0043111"(replication fork arrest)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|refseq:NP_010016.2|sgd:S000000688|mint:P25336|dip:DIP-2422N	-	-	crc64:1AD91C2E2F2856EF	figure legend:Figure 2|comment:Binding increased when 32P-labeled DNA duplexes contained a loop that was 2, 4, 8 or 14 nucleotides in length  located in the middle of the duplex, in proportion to the length of the loop.|comment:"Msh2-Msh3 did not bind to a duplex containing a G/T mismatch (EBI-1368887), nor could this act as an inhibitor of complex binding to the actual binding duplex"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/07/12	2014/10/16	crc64:DABCC1DABAC9CF03	rogid:+wUVIWkJoR5KHA7YuIYdskdQszE559292	intact-crc:2F78F1BC46948971	false	-	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
intact:EBI-1368872	uniprotkb:P25847	-	intact:EBI-11352|uniprotkb:Q12423|ensemblfungi:YOL090W|uniprotkb:D6W1X8	psi-mi:msh2-msh3-binding(display_short)|psi-mi:EBI-1368872(display_long)	psi-mi:msh2_yeast(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:YOL090W(locus name)|uniprotkb:O0935(orf name)|uniprotkb:MutS protein homolog 2(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Habraken et al. (1996)	pubmed:8805366	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1368880	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0681"(double stranded deoxyribonucleic acid)	psi-mi:"MI:0326"(protein)	-	ensemblfungi:YOL090W(gene)|ensemblfungi:YOL090W_mRNA(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000710"(meiotic mismatch repair)|go:"GO:0000735"(removal of nonhomologous ends)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006312"(mitotic recombination)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043111"(replication fork arrest)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|reactome:R-SCE-5358565|reactome:R-SCE-5358606|go:"GO:0032300"(mismatch repair complex)|refseq:NP_014551.1|sgd:S000005450|mint:P25847|dip:DIP-2415N	-	-	crc64:43FFD8A640138AE4	figure legend:Figure 2|comment:Binding increased when 32P-labeled DNA duplexes contained a loop that was 2, 4, 8 or 14 nucleotides in length  located in the middle of the duplex, in proportion to the length of the loop.|comment:"Msh2-Msh3 did not bind to a duplex containing a G/T mismatch (EBI-1368887), nor could this act as an inhibitor of complex binding to the actual binding duplex"	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/07/12	2014/10/16	crc64:DABCC1DABAC9CF03	rogid:PNwekSiaI58qR+dPZZQW5UNRJ+4559292	intact-crc:2F78F1BC46948971	false	-	-	-	1	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)