#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P43132	uniprotkb:P38827	intact:EBI-27115|uniprotkb:E9PA88|uniprotkb:D6VY17|ensemblfungi:YLR015W	intact:EBI-16977|uniprotkb:D3DL69|ensemblfungi:YHR119W	psi-mi:bre2_yeast(display_long)|uniprotkb:Complex proteins associated with SET1 protein BRE2(gene name synonym)|uniprotkb:Set1C component BRE2(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 2(gene name synonym)|uniprotkb:CPS60(gene name synonym)|uniprotkb:YLR015W(locus name)|uniprotkb:BRE2(gene name)|psi-mi:BRE2(display_short)	psi-mi:set1_yeast(display_long)|uniprotkb:SET1(gene name)|psi-mi:SET1(display_short)|uniprotkb:YTX1(gene name synonym)|uniprotkb:KMT2(gene name synonym)|uniprotkb:COMPASS component SET1(gene name synonym)|uniprotkb:SET domain-containing protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2(gene name synonym)|uniprotkb:YHR119W(locus name)	psi-mi:"MI:0071"(molecular sieving)	Lee et al. (2007)	imex:IM-11977|pubmed:18083099	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1569014|imex:IM-11977-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013115.1|sgd:S000004005|mint:P43132|dip:DIP-1935N|ensemblfungi:YLR015W(gene)|ensemblfungi:YLR015W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0006348"|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|rcsb pdb:4RT4|rcsb pdb:6BX3|rcsb pdb:6VEN	ensemblfungi:YHR119W(gene)|ensemblfungi:YHR119W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0006348"|go:"GO:0006479"(protein methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0030437"(ascospore formation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1903341"(regulation of meiotic DNA double-strand break formation)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017111(Histone H3-K4 methyltransferase Set1)|interpro:IPR024636|interpro:IPR024657|interpro:IPR044570|rcsb pdb:2J8A|rcsb pdb:6VEN|reactome:R-SCE-3214841|refseq:NP_011987.1|sgd:S000001161|dip:DIP-4616N|mint:P38827	psi-mi:"MI:0469"(intact)	crc64:D5B33221E9F10379	crc64:B7FA5D60F71063FD	figure legend:Fig. 2I and 2J|comment:A point lys124arg mutation in Histone 2B prevents this interaction from occuring|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/17	2014/10/16	rogid:FtUWm7O2HN+lGMg0I1rS694mWMQ559292	rogid:QviRdWKz1+2O63RmD9p2MeyA9Jg559292	intact-crc:50BE4925E39F9AA4|rigid:5Fq9QFoGVIfh+86llqlLWOln4iQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P38827	uniprotkb:P36104	intact:EBI-16977|uniprotkb:D3DL69|ensemblfungi:YHR119W	intact:EBI-26608|uniprotkb:D6VXR8|ensemblfungi:YKL018W	psi-mi:set1_yeast(display_long)|uniprotkb:SET1(gene name)|psi-mi:SET1(display_short)|uniprotkb:YTX1(gene name synonym)|uniprotkb:KMT2(gene name synonym)|uniprotkb:COMPASS component SET1(gene name synonym)|uniprotkb:SET domain-containing protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2(gene name synonym)|uniprotkb:YHR119W(locus name)	psi-mi:swd2_yeast(display_long)|uniprotkb:CPS35(gene name synonym)|uniprotkb:YKL018W(locus name)|uniprotkb:SWD2(gene name)|psi-mi:SWD2(display_short)|uniprotkb:SAF37(gene name synonym)|uniprotkb:Complex proteins associated with SET1 protein SWD2(gene name synonym)|uniprotkb:Set1C component SWD2(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Lee et al. (2007)	imex:IM-11977|pubmed:18083099	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1569020|imex:IM-11977-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR119W(gene)|ensemblfungi:YHR119W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0006348"|go:"GO:0006479"(protein methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0030437"(ascospore formation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1903341"(regulation of meiotic DNA double-strand break formation)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017111(Histone H3-K4 methyltransferase Set1)|interpro:IPR024636|interpro:IPR024657|interpro:IPR044570|rcsb pdb:2J8A|rcsb pdb:6VEN|reactome:R-SCE-3214841|refseq:NP_011987.1|sgd:S000001161|dip:DIP-4616N|mint:P38827	sgd:S000001501|refseq:NP_012907.3|mint:P36104|dip:DIP-6844N|ensemblfungi:YKL018W(gene)|ensemblfungi:YKL018W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037867	psi-mi:"MI:0469"(intact)	crc64:B7FA5D60F71063FD	crc64:5453C193A5C0AEEC	figure legend:Fig. 3|comment:A point lys124arg mutation in Histone 2B prevents this interaction from occuring|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/17	2014/10/16	rogid:QviRdWKz1+2O63RmD9p2MeyA9Jg559292	rogid:XvCuGlH+mrlrlbO3LN/z+8E0cQI559292	intact-crc:DAC49D98FF6F66C2|rigid:6o6i+hdb19ITRfFJOaGy/QWwJm8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P43132	uniprotkb:P36104	intact:EBI-27115|uniprotkb:E9PA88|uniprotkb:D6VY17|ensemblfungi:YLR015W	intact:EBI-26608|uniprotkb:D6VXR8|ensemblfungi:YKL018W	psi-mi:bre2_yeast(display_long)|uniprotkb:Complex proteins associated with SET1 protein BRE2(gene name synonym)|uniprotkb:Set1C component BRE2(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 2(gene name synonym)|uniprotkb:CPS60(gene name synonym)|uniprotkb:YLR015W(locus name)|uniprotkb:BRE2(gene name)|psi-mi:BRE2(display_short)	psi-mi:swd2_yeast(display_long)|uniprotkb:CPS35(gene name synonym)|uniprotkb:YKL018W(locus name)|uniprotkb:SWD2(gene name)|psi-mi:SWD2(display_short)|uniprotkb:SAF37(gene name synonym)|uniprotkb:Complex proteins associated with SET1 protein SWD2(gene name synonym)|uniprotkb:Set1C component SWD2(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Lee et al. (2007)	imex:IM-11977|pubmed:18083099	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1569029|imex:IM-11977-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013115.1|sgd:S000004005|mint:P43132|dip:DIP-1935N|ensemblfungi:YLR015W(gene)|ensemblfungi:YLR015W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0006348"|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|rcsb pdb:4RT4|rcsb pdb:6BX3|rcsb pdb:6VEN	sgd:S000001501|refseq:NP_012907.3|mint:P36104|dip:DIP-6844N|ensemblfungi:YKL018W(gene)|ensemblfungi:YKL018W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037867	psi-mi:"MI:0469"(intact)	crc64:D5B33221E9F10379	crc64:5453C193A5C0AEEC	comment:"Loss of H2B monoubiquitination (lys124arg mutation) in the cell results in the loss of the association of Swd2 and Shg1 within the complex"|figure legend:Fig. 4|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/17	2014/10/16	rogid:FtUWm7O2HN+lGMg0I1rS694mWMQ559292	rogid:XvCuGlH+mrlrlbO3LN/z+8E0cQI559292	intact-crc:1E35191130EC4301|rigid:dU3COtARb1to/CeI4nKesq4omCs	false	calmodulin binding peptide plus protein a tag:?-?	-	2	1	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:P43132	uniprotkb:Q03012	intact:EBI-27115|uniprotkb:E9PA88|uniprotkb:D6VY17|ensemblfungi:YLR015W	intact:EBI-32540|uniprotkb:D6W3N0|ensemblfungi:YPL138C	psi-mi:bre2_yeast(display_long)|uniprotkb:Complex proteins associated with SET1 protein BRE2(gene name synonym)|uniprotkb:Set1C component BRE2(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 2(gene name synonym)|uniprotkb:CPS60(gene name synonym)|uniprotkb:YLR015W(locus name)|uniprotkb:BRE2(gene name)|psi-mi:BRE2(display_short)	psi-mi:spp1_yeast(display_long)|uniprotkb:SPP1(gene name)|psi-mi:SPP1(display_short)|uniprotkb:SAF41(gene name synonym)|uniprotkb:Complex proteins associated with SET1 protein SPP1(gene name synonym)|uniprotkb:Set1C component SPP1(gene name synonym)|uniprotkb:Suppressor of PRP protein 1(gene name synonym)|uniprotkb:CPS40(gene name synonym)|uniprotkb:YPL138C(locus name)	psi-mi:"MI:0676"(tandem affinity purification)	Lee et al. (2007)	imex:IM-11977|pubmed:18083099	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1569029|imex:IM-11977-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013115.1|sgd:S000004005|mint:P43132|dip:DIP-1935N|ensemblfungi:YLR015W(gene)|ensemblfungi:YLR015W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0006348"|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|rcsb pdb:4RT4|rcsb pdb:6BX3|rcsb pdb:6VEN	refseq:NP_015187.1|sgd:S000006059|dip:DIP-2946N|mint:Q03012|ensemblfungi:YPL138C(gene)|ensemblfungi:YPL138C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:1903341"(regulation of meiotic DNA double-strand break formation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR037869|rcsb pdb:6BX3|rcsb pdb:6J2P|rcsb pdb:6VEN	psi-mi:"MI:0469"(intact)	crc64:D5B33221E9F10379	crc64:F4B8DFE0CB358CA4	comment:"Loss of H2B monoubiquitination (lys124arg mutation) in the cell results in the loss of the association of Swd2 and Shg1 within the complex"|figure legend:Fig. 4|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/17	2014/10/16	rogid:FtUWm7O2HN+lGMg0I1rS694mWMQ559292	rogid:Jb0V/TLti1V5RRaaSH+tIRrLtf8559292	intact-crc:1E35191130EC4301|rigid:dU3COtARb1to/CeI4nKesq4omCs	false	calmodulin binding peptide plus protein a tag:?-?	-	2	2	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:P43132	uniprotkb:Q03323	intact:EBI-27115|uniprotkb:E9PA88|uniprotkb:D6VY17|ensemblfungi:YLR015W	intact:EBI-38307|uniprotkb:D6VT93|ensemblfungi:YDR469W	psi-mi:bre2_yeast(display_long)|uniprotkb:Complex proteins associated with SET1 protein BRE2(gene name synonym)|uniprotkb:Set1C component BRE2(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 2(gene name synonym)|uniprotkb:CPS60(gene name synonym)|uniprotkb:YLR015W(locus name)|uniprotkb:BRE2(gene name)|psi-mi:BRE2(display_short)	psi-mi:sdc1_yeast(display_long)|uniprotkb:SDC1(gene name)|psi-mi:SDC1(display_short)|uniprotkb:SAF19(gene name synonym)|uniprotkb:CPS25(gene name synonym)|uniprotkb:YDR469W(locus name)|uniprotkb:Complex proteins associated with SET1 protein SDC1(gene name synonym)|uniprotkb:Set1C component SDC1(gene name synonym)|uniprotkb:Suppressor of CDC25 protein 1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Lee et al. (2007)	imex:IM-11977|pubmed:18083099	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1569029|imex:IM-11977-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013115.1|sgd:S000004005|mint:P43132|dip:DIP-1935N|ensemblfungi:YLR015W(gene)|ensemblfungi:YLR015W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0006348"|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|rcsb pdb:4RT4|rcsb pdb:6BX3|rcsb pdb:6VEN	sgd:S000002877|refseq:NP_010757.3|mint:Q03323|dip:DIP-1738N|ensemblfungi:YDR469W(gene)|ensemblfungi:YDR469W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|rcsb pdb:6BX3|rcsb pdb:6VEN	psi-mi:"MI:0469"(intact)	crc64:D5B33221E9F10379	crc64:B40247D641124306	comment:"Loss of H2B monoubiquitination (lys124arg mutation) in the cell results in the loss of the association of Swd2 and Shg1 within the complex"|figure legend:Fig. 4|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/17	2014/10/16	rogid:FtUWm7O2HN+lGMg0I1rS694mWMQ559292	rogid:rqONb5FbTwa65H4M7FRXMFJduJA559292	intact-crc:1E35191130EC4301|rigid:dU3COtARb1to/CeI4nKesq4omCs	false	calmodulin binding peptide plus protein a tag:?-?	-	2	6	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:P43132	uniprotkb:P38123	intact:EBI-27115|uniprotkb:E9PA88|uniprotkb:D6VY17|ensemblfungi:YLR015W	intact:EBI-20881|uniprotkb:D6VQH0|ensemblfungi:YBR175W	psi-mi:bre2_yeast(display_long)|uniprotkb:Complex proteins associated with SET1 protein BRE2(gene name synonym)|uniprotkb:Set1C component BRE2(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 2(gene name synonym)|uniprotkb:CPS60(gene name synonym)|uniprotkb:YLR015W(locus name)|uniprotkb:BRE2(gene name)|psi-mi:BRE2(display_short)	psi-mi:swd3_yeast(display_long)|uniprotkb:CPS30(gene name synonym)|uniprotkb:YBR175W(locus name)|uniprotkb:YBR1237(orf name)|uniprotkb:SWD3(gene name)|psi-mi:SWD3(display_short)|uniprotkb:SAF35(gene name synonym)|uniprotkb:Complex proteins associated with SET1 protein SWD3(gene name synonym)|uniprotkb:Set1C component SWD3(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Lee et al. (2007)	imex:IM-11977|pubmed:18083099	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1569029|imex:IM-11977-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013115.1|sgd:S000004005|mint:P43132|dip:DIP-1935N|ensemblfungi:YLR015W(gene)|ensemblfungi:YLR015W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0006348"|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|rcsb pdb:4RT4|rcsb pdb:6BX3|rcsb pdb:6VEN	refseq:NP_009734.1|sgd:S000000379|mint:P38123|ensemblfungi:YBR175W(gene)|ensemblfungi:YBR175W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0042393"(histone binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:1903341"(regulation of meiotic DNA double-strand break formation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|rcsb pdb:6BX3|rcsb pdb:6VEN|dip:DIP-1754N	psi-mi:"MI:0469"(intact)	crc64:D5B33221E9F10379	crc64:E8E88C483D1CD776	comment:"Loss of H2B monoubiquitination (lys124arg mutation) in the cell results in the loss of the association of Swd2 and Shg1 within the complex"|figure legend:Fig. 4|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/17	2014/10/16	rogid:FtUWm7O2HN+lGMg0I1rS694mWMQ559292	rogid:hldGrun5mx4U9gqKP+j0WGVphHg559292	intact-crc:1E35191130EC4301|rigid:dU3COtARb1to/CeI4nKesq4omCs	false	calmodulin binding peptide plus protein a tag:?-?	-	2	1	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:P43132	uniprotkb:P38827	intact:EBI-27115|uniprotkb:E9PA88|uniprotkb:D6VY17|ensemblfungi:YLR015W	intact:EBI-16977|uniprotkb:D3DL69|ensemblfungi:YHR119W	psi-mi:bre2_yeast(display_long)|uniprotkb:Complex proteins associated with SET1 protein BRE2(gene name synonym)|uniprotkb:Set1C component BRE2(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 2(gene name synonym)|uniprotkb:CPS60(gene name synonym)|uniprotkb:YLR015W(locus name)|uniprotkb:BRE2(gene name)|psi-mi:BRE2(display_short)	psi-mi:set1_yeast(display_long)|uniprotkb:SET1(gene name)|psi-mi:SET1(display_short)|uniprotkb:YTX1(gene name synonym)|uniprotkb:KMT2(gene name synonym)|uniprotkb:COMPASS component SET1(gene name synonym)|uniprotkb:SET domain-containing protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2(gene name synonym)|uniprotkb:YHR119W(locus name)	psi-mi:"MI:0676"(tandem affinity purification)	Lee et al. (2007)	imex:IM-11977|pubmed:18083099	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1569029|imex:IM-11977-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013115.1|sgd:S000004005|mint:P43132|dip:DIP-1935N|ensemblfungi:YLR015W(gene)|ensemblfungi:YLR015W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0006348"|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|rcsb pdb:4RT4|rcsb pdb:6BX3|rcsb pdb:6VEN	ensemblfungi:YHR119W(gene)|ensemblfungi:YHR119W_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0006348"|go:"GO:0006479"(protein methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0030437"(ascospore formation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0055092"(sterol homeostasis)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1902275"(regulation of chromatin organization)|go:"GO:1903341"(regulation of meiotic DNA double-strand break formation)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017111(Histone H3-K4 methyltransferase Set1)|interpro:IPR024636|interpro:IPR024657|interpro:IPR044570|rcsb pdb:2J8A|rcsb pdb:6VEN|reactome:R-SCE-3214841|refseq:NP_011987.1|sgd:S000001161|dip:DIP-4616N|mint:P38827	psi-mi:"MI:0469"(intact)	crc64:D5B33221E9F10379	crc64:B7FA5D60F71063FD	comment:"Loss of H2B monoubiquitination (lys124arg mutation) in the cell results in the loss of the association of Swd2 and Shg1 within the complex"|figure legend:Fig. 4|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/17	2014/10/16	rogid:FtUWm7O2HN+lGMg0I1rS694mWMQ559292	rogid:QviRdWKz1+2O63RmD9p2MeyA9Jg559292	intact-crc:1E35191130EC4301|rigid:dU3COtARb1to/CeI4nKesq4omCs	false	calmodulin binding peptide plus protein a tag:?-?	-	2	2	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:P43132	uniprotkb:P38337	intact:EBI-27115|uniprotkb:E9PA88|uniprotkb:D6VY17|ensemblfungi:YLR015W	intact:EBI-21106|uniprotkb:D6VQQ5|ensemblfungi:YBR258C	psi-mi:bre2_yeast(display_long)|uniprotkb:Complex proteins associated with SET1 protein BRE2(gene name synonym)|uniprotkb:Set1C component BRE2(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 2(gene name synonym)|uniprotkb:CPS60(gene name synonym)|uniprotkb:YLR015W(locus name)|uniprotkb:BRE2(gene name)|psi-mi:BRE2(display_short)	psi-mi:shg1_yeast(display_long)|uniprotkb:CPS15(gene name synonym)|uniprotkb:YBR258C(locus name)|uniprotkb:YBR1726(orf name)|uniprotkb:SHG1(gene name)|psi-mi:SHG1(display_short)|uniprotkb:Complex proteins associated with SET1 protein SHG1(gene name synonym)|uniprotkb:Set1C component SHG1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Lee et al. (2007)	imex:IM-11977|pubmed:18083099	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1569029|imex:IM-11977-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013115.1|sgd:S000004005|mint:P43132|dip:DIP-1935N|ensemblfungi:YLR015W(gene)|ensemblfungi:YLR015W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0006348"|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|rcsb pdb:4RT4|rcsb pdb:6BX3|rcsb pdb:6VEN	refseq:NP_009817.3|sgd:S000000462|mint:P38337|dip:DIP-6843N|ensemblfungi:YBR258C(gene)|ensemblfungi:YBR258C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)	psi-mi:"MI:0469"(intact)	crc64:D5B33221E9F10379	-	comment:"Loss of H2B monoubiquitination (lys124arg mutation) in the cell results in the loss of the association of Swd2 and Shg1 within the complex"|figure legend:Fig. 4|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/17	2014/10/16	rogid:FtUWm7O2HN+lGMg0I1rS694mWMQ559292	rogid:lsPFil5B2zxwMWXH28ZAiFwgkF8559292	intact-crc:1E35191130EC4301|rigid:dU3COtARb1to/CeI4nKesq4omCs	false	calmodulin binding peptide plus protein a tag:?-?	-	2	1	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
uniprotkb:P43132	uniprotkb:P39706	intact:EBI-27115|uniprotkb:E9PA88|uniprotkb:D6VY17|ensemblfungi:YLR015W	intact:EBI-20737|uniprotkb:D6VPL8|ensemblfungi:YAR003W	psi-mi:bre2_yeast(display_long)|uniprotkb:Complex proteins associated with SET1 protein BRE2(gene name synonym)|uniprotkb:Set1C component BRE2(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 2(gene name synonym)|uniprotkb:CPS60(gene name synonym)|uniprotkb:YLR015W(locus name)|uniprotkb:BRE2(gene name)|psi-mi:BRE2(display_short)	psi-mi:swd1_yeast(display_long)|uniprotkb:CPS50(gene name synonym)|uniprotkb:YAR003W(locus name)|uniprotkb:FUN16(orf name)|uniprotkb:SWD1(gene name)|psi-mi:SWD1(display_short)|uniprotkb:SAF49(gene name synonym)|uniprotkb:Complex proteins associated with SET1 protein SWD1(gene name synonym)|uniprotkb:Set1C component SWD1(gene name synonym)	psi-mi:"MI:0676"(tandem affinity purification)	Lee et al. (2007)	imex:IM-11977|pubmed:18083099	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1569029|imex:IM-11977-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013115.1|sgd:S000004005|mint:P43132|dip:DIP-1935N|ensemblfungi:YLR015W(gene)|ensemblfungi:YLR015W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0006348"|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|rcsb pdb:4RT4|rcsb pdb:6BX3|rcsb pdb:6VEN	refseq:NP_009403.1|sgd:S000000064|mint:P39706|ensemblfungi:YAR003W(gene)|ensemblfungi:YAR003W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037850|rcsb pdb:6VEN|dip:DIP-1753N|rcsb pdb:6BX3	psi-mi:"MI:0469"(intact)	crc64:D5B33221E9F10379	crc64:90C389612AB66231	comment:"Loss of H2B monoubiquitination (lys124arg mutation) in the cell results in the loss of the association of Swd2 and Shg1 within the complex"|figure legend:Fig. 4|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/17	2014/10/16	rogid:FtUWm7O2HN+lGMg0I1rS694mWMQ559292	rogid:75cD/C5VASvtXCNuluO7F3Fi19o559292	intact-crc:1E35191130EC4301|rigid:dU3COtARb1to/CeI4nKesq4omCs	false	calmodulin binding peptide plus protein a tag:?-?	-	2	1	psi-mi:"MI:0658"(multidimensional protein identification technology)	psi-mi:"MI:0658"(multidimensional protein identification technology)
ensembl:YBR020W	uniprotkb:P36104	intact:EBI-1569042	intact:EBI-26608|uniprotkb:D6VXR8|ensemblfungi:YKL018W	psi-mi:gal1_yeast_gene(display_short)|psi-mi:YBR020W(display_long)	psi-mi:swd2_yeast(display_long)|uniprotkb:CPS35(gene name synonym)|uniprotkb:YKL018W(locus name)|uniprotkb:SWD2(gene name)|psi-mi:SWD2(display_short)|uniprotkb:SAF37(gene name synonym)|uniprotkb:Complex proteins associated with SET1 protein SWD2(gene name synonym)|uniprotkb:Set1C component SWD2(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Lee et al. (2007)	imex:IM-11977|pubmed:18083099	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1569048|imex:IM-11977-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	sgd:S000001501|refseq:NP_012907.3|mint:P36104|dip:DIP-6844N|ensemblfungi:YKL018W(gene)|ensemblfungi:YKL018W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037867	-	-	crc64:5453C193A5C0AEEC	comment:The presence of Cps35 at GAL1 is reduced by 90% in the strains lacking rad6 or bearing the Histone H2B K124R single point mutation|figure legend:Fig. 5 and 6E|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/17	2014/10/16	-	rogid:XvCuGlH+mrlrlbO3LN/z+8E0cQI559292	intact-crc:884B232B899AD1B0	false	-	myc tag:?-?	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)
uniprotkb:P43132	ensembl:YBR020W	intact:EBI-27115|uniprotkb:E9PA88|uniprotkb:D6VY17|ensemblfungi:YLR015W	intact:EBI-1569042	psi-mi:bre2_yeast(display_long)|uniprotkb:Complex proteins associated with SET1 protein BRE2(gene name synonym)|uniprotkb:Set1C component BRE2(gene name synonym)|uniprotkb:Brefeldin-A sensitivity protein 2(gene name synonym)|uniprotkb:CPS60(gene name synonym)|uniprotkb:YLR015W(locus name)|uniprotkb:BRE2(gene name)|psi-mi:BRE2(display_short)	psi-mi:gal1_yeast_gene(display_short)|psi-mi:YBR020W(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Lee et al. (2007)	imex:IM-11977|pubmed:18083099	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1569056|imex:IM-11977-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_013115.1|sgd:S000004005|mint:P43132|dip:DIP-1935N|ensemblfungi:YLR015W(gene)|ensemblfungi:YLR015W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0006348"|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|rcsb pdb:4RT4|rcsb pdb:6BX3|rcsb pdb:6VEN	-	-	crc64:D5B33221E9F10379	-	figure legend:Fig. 5|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/17	2014/10/16	rogid:FtUWm7O2HN+lGMg0I1rS694mWMQ559292	-	intact-crc:64484A79E7F3EC8F	false	calmodulin binding peptide plus protein a tag:?-?	-	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)
ensembl:YOL086C	uniprotkb:P36104	intact:EBI-1569063	intact:EBI-26608|uniprotkb:D6VXR8|ensemblfungi:YKL018W	psi-mi:adh1_yeast_gene(display_short)|psi-mi:YOL086C(display_long)	psi-mi:swd2_yeast(display_long)|uniprotkb:CPS35(gene name synonym)|uniprotkb:YKL018W(locus name)|uniprotkb:SWD2(gene name)|psi-mi:SWD2(display_short)|uniprotkb:SAF37(gene name synonym)|uniprotkb:Complex proteins associated with SET1 protein SWD2(gene name synonym)|uniprotkb:Set1C component SWD2(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Lee et al. (2007)	imex:IM-11977|pubmed:18083099	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1569067|imex:IM-11977-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	sgd:S000001501|refseq:NP_012907.3|mint:P36104|dip:DIP-6844N|ensemblfungi:YKL018W(gene)|ensemblfungi:YKL018W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037867	-	-	crc64:5453C193A5C0AEEC	comment:The presence of Cps35 at ADH1 is reduced by 90% in the strains lacking rad6 or bearing the Histone H2B K124R single point mutation|figure legend:Fig. 5D|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/17	2014/10/16	-	rogid:XvCuGlH+mrlrlbO3LN/z+8E0cQI559292	intact-crc:31B66F0BE70409B9	false	-	myc tag:?-?	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)
ensembl:YML123C	uniprotkb:P36104	intact:EBI-1559695	intact:EBI-26608|uniprotkb:D6VXR8|ensemblfungi:YKL018W	psi-mi:pho84_yeast_gene(display_short)|psi-mi:YML123C(display_long)	psi-mi:swd2_yeast(display_long)|uniprotkb:CPS35(gene name synonym)|uniprotkb:YKL018W(locus name)|uniprotkb:SWD2(gene name)|psi-mi:SWD2(display_short)|uniprotkb:SAF37(gene name synonym)|uniprotkb:Complex proteins associated with SET1 protein SWD2(gene name synonym)|uniprotkb:Set1C component SWD2(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Lee et al. (2007)	imex:IM-11977|pubmed:18083099	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1569075|imex:IM-11977-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	sgd:S000001501|refseq:NP_012907.3|mint:P36104|dip:DIP-6844N|ensemblfungi:YKL018W(gene)|ensemblfungi:YKL018W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037867	-	-	crc64:5453C193A5C0AEEC	comment:The presence of Cps35 at pho84 is reduced by 90% in the strains lacking rad6 or bearing the Histone H2B K124R single point mutation|figure legend:Fig. 5E|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/17	2014/10/16	-	rogid:XvCuGlH+mrlrlbO3LN/z+8E0cQI559292	intact-crc:28F0461F00C76CF9	false	-	myc tag:?-?	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)
uniprotkb:P61830	ensembl:YBR020W	intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C	intact:EBI-1569042	psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short)	psi-mi:gal1_yeast_gene(display_short)|psi-mi:YBR020W(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Lee et al. (2007)	imex:IM-11977|pubmed:18083099	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1569106|imex:IM-11977-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G	-	-	crc64:A6115FEB480AC67A	-	comment:This interaction cannot be detected using anti-H3-dimethyl K5 Abs in the absence of Set1|figure legend:Fig. 5 and 6D|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/17	2014/10/16	rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292	-	intact-crc:39E1E954501A239A	false	N6,N6-dimethyl-L-lysine:5-5	-	-	-	psi-mi:"MI:0056"(full identification by DNA sequencing)	psi-mi:"MI:0056"(full identification by DNA sequencing)
uniprotkb:Q04089	uniprotkb:P36104	intact:EBI-6046|uniprotkb:D6VT67|ensemblfungi:YDR440W	intact:EBI-26608|uniprotkb:D6VXR8|ensemblfungi:YKL018W	psi-mi:dot1_yeast(display_long)|uniprotkb:DOT1(gene name)|psi-mi:DOT1(display_short)|uniprotkb:PCH1(gene name synonym)|uniprotkb:YDR440W(locus name)|uniprotkb:D9461.26(orf name)|uniprotkb:KMT4(gene name synonym)|uniprotkb:Histone H3-K79 methyltransferase(gene name synonym)|uniprotkb:Disrupter of telomere silencing protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 4(gene name synonym)	psi-mi:swd2_yeast(display_long)|uniprotkb:CPS35(gene name synonym)|uniprotkb:YKL018W(locus name)|uniprotkb:SWD2(gene name)|psi-mi:SWD2(display_short)|uniprotkb:SAF37(gene name synonym)|uniprotkb:Complex proteins associated with SET1 protein SWD2(gene name synonym)|uniprotkb:Set1C component SWD2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lee et al. (2007)	imex:IM-11977|pubmed:18083099	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1569086|imex:IM-11977-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010728.1|sgd:S000002848|dip:DIP-2560N|mint:Q04089|ensemblfungi:YDR440W(gene)|ensemblfungi:YDR440W_mRNA(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000725"(recombinational repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006348"|go:"GO:0031151"("histone methyltransferase activity (H3-K79 specific)")|go:"GO:0031452"(negative regulation of heterochromatin assembly)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0043486"(histone exchange)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0070911"(global genome nucleotide-excision repair)|go:"GO:2000677"(regulation of transcription regulatory region DNA binding)|interpro:IPR021162|interpro:IPR025789|interpro:IPR029063|interpro:IPR030445|rcsb pdb:1M0R|rcsb pdb:1U2Z|rcsb pdb:7K6P|rcsb pdb:7K6Q|reactome:R-SCE-3214841	sgd:S000001501|refseq:NP_012907.3|mint:P36104|dip:DIP-6844N|ensemblfungi:YKL018W(gene)|ensemblfungi:YKL018W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0031126"("sno(s)RNA 3'-end processing")|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037867	psi-mi:"MI:0469"(intact)	-	crc64:5453C193A5C0AEEC	figure legend:Fig. 6A|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/12/17	2014/10/16	rogid:dnJs8Rl0xiEb0XmVRtZIB48VVOs559292	rogid:XvCuGlH+mrlrlbO3LN/z+8E0cQI559292	intact-crc:6706905E6EB00355|rigid:be7u88BMGgdFyz+6N0phw7m+918	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)