#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P11309-2 uniprotkb:Q9UNQ0 intact:EBI-1018633|intact:EBI-20775148 intact:EBI-1569435|uniprotkb:A0A1W3|uniprotkb:O95374|uniprotkb:Q53ZQ1|uniprotkb:Q569L4|uniprotkb:Q5YLG4|uniprotkb:Q86V64|uniprotkb:Q8IX16|uniprotkb:Q96LD6|uniprotkb:Q96TA8|uniprotkb:Q9BY73|uniprotkb:Q9NUS0|uniprotkb:Q4W5I3|uniprotkb:A8K1T5|ensembl:ENSP00000237612|ensembl:ENSP00000498246 psi-mi:p11309-2(display_long)|uniprotkb:Pim-1L(isoform synonym)|uniprotkb:PIM1(gene name)|psi-mi:PIM1(display_short) psi-mi:abcg2_human(display_long)|uniprotkb:Placenta-specific ATP-binding cassette transporter(gene name synonym)|uniprotkb:Breast cancer resistance protein(gene name synonym)|uniprotkb:Mitoxantrone resistance-associated protein(gene name synonym)|uniprotkb:CDw338(gene name synonym)|uniprotkb:ABCG2(gene name)|psi-mi:ABCG2(display_short)|uniprotkb:ABCP(gene name synonym)|uniprotkb:BCRP(gene name synonym)|uniprotkb:BCRP1(gene name synonym)|uniprotkb:MXR(gene name synonym)|uniprotkb:Urate exporter(gene name synonym)|uniprotkb:ATP-binding cassette sub-family G member 2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Xie et al. (2007) pubmed:18056989|imex:IM-26546 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1569472|imex:IM-26546-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-696621(pim1_human)|uniprotkb:P11309-2(isoform-parent) refseq:NP_004818.2|refseq:XP_011530722.1|refseq:NP_001244315.1|refseq:XP_005263412.1|dip:DIP-29162N|ensembl:ENSG00000118777(gene)|ensembl:ENST00000237612(transcript)|ensembl:ENST00000650821(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008514"(organic anion transmembrane transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015711"(organic anion transport)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032217"(riboflavin transmembrane transporter activity)|go:"GO:0032218"(riboflavin transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046415"(urate metabolic process)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070633"(transepithelial transport)|go:"GO:0097744"(renal urate salt excretion)|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1990748"(cellular detoxification)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR030256|interpro:IPR043926|mint:Q9UNQ0|rcsb pdb:5NJ3|rcsb pdb:5NJG|rcsb pdb:6ETI|rcsb pdb:6FEQ|rcsb pdb:6FFC|rcsb pdb:6HBU|rcsb pdb:6HCO|rcsb pdb:6HIJ|rcsb pdb:6HZM|rcsb pdb:6VXF|rcsb pdb:6VXH|rcsb pdb:6VXI|rcsb pdb:6VXJ|rcsb pdb:7NEQ|rcsb pdb:7NEZ|rcsb pdb:7NFD|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2161517|reactome:R-HSA-917937 - isoform-comment:Initiates from CTG codon. - comment:The PIM-1 protein used as the bait is a kinase inactive mutant.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/12/18 2018/10/30 rogid:LMhWNRm+1/0PVcUHBDVt6kiwD149606 rogid:WVlV2boR+rIKWZOKk7VRlJJOCfk9606 intact-crc:B8FBC1A05C5B1197|rigid:gY8f514gNV6rc77F0saPPm7pwI4 false mutation:158-158 - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P11309-2 uniprotkb:Q9UNQ0 intact:EBI-1018633|intact:EBI-20775148 intact:EBI-1569435|uniprotkb:A0A1W3|uniprotkb:O95374|uniprotkb:Q53ZQ1|uniprotkb:Q569L4|uniprotkb:Q5YLG4|uniprotkb:Q86V64|uniprotkb:Q8IX16|uniprotkb:Q96LD6|uniprotkb:Q96TA8|uniprotkb:Q9BY73|uniprotkb:Q9NUS0|uniprotkb:Q4W5I3|uniprotkb:A8K1T5|ensembl:ENSP00000237612|ensembl:ENSP00000498246 psi-mi:p11309-2(display_long)|uniprotkb:Pim-1L(isoform synonym)|uniprotkb:PIM1(gene name)|psi-mi:PIM1(display_short) psi-mi:abcg2_human(display_long)|uniprotkb:Placenta-specific ATP-binding cassette transporter(gene name synonym)|uniprotkb:Breast cancer resistance protein(gene name synonym)|uniprotkb:Mitoxantrone resistance-associated protein(gene name synonym)|uniprotkb:CDw338(gene name synonym)|uniprotkb:ABCG2(gene name)|psi-mi:ABCG2(display_short)|uniprotkb:ABCP(gene name synonym)|uniprotkb:BCRP(gene name synonym)|uniprotkb:BCRP1(gene name synonym)|uniprotkb:MXR(gene name synonym)|uniprotkb:Urate exporter(gene name synonym)|uniprotkb:ATP-binding cassette sub-family G member 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Xie et al. (2007) pubmed:18056989|imex:IM-26546 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1569536|imex:IM-26546-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-696621(pim1_human)|uniprotkb:P11309-2(isoform-parent) refseq:NP_004818.2|refseq:XP_011530722.1|refseq:NP_001244315.1|refseq:XP_005263412.1|dip:DIP-29162N|ensembl:ENSG00000118777(gene)|ensembl:ENST00000237612(transcript)|ensembl:ENST00000650821(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008514"(organic anion transmembrane transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015711"(organic anion transport)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032217"(riboflavin transmembrane transporter activity)|go:"GO:0032218"(riboflavin transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046415"(urate metabolic process)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070633"(transepithelial transport)|go:"GO:0097744"(renal urate salt excretion)|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1990748"(cellular detoxification)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR030256|interpro:IPR043926|mint:Q9UNQ0|rcsb pdb:5NJ3|rcsb pdb:5NJG|rcsb pdb:6ETI|rcsb pdb:6FEQ|rcsb pdb:6FFC|rcsb pdb:6HBU|rcsb pdb:6HCO|rcsb pdb:6HIJ|rcsb pdb:6HZM|rcsb pdb:6VXF|rcsb pdb:6VXH|rcsb pdb:6VXI|rcsb pdb:6VXJ|rcsb pdb:7NEQ|rcsb pdb:7NEZ|rcsb pdb:7NFD|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2161517|reactome:R-HSA-917937 intact:EBI-1569536(see-also) isoform-comment:Initiates from CTG codon. - figure legend:1 A|delivery method:Q9UNQ0; P11309-1 transfection|comment:The data suggest that this interaction requires both the N-terminal proline-rich region and the kinase domain present in Pim-1L but not Pim-1S.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2007/12/18 2018/10/22 rogid:LMhWNRm+1/0PVcUHBDVt6kiwD149606 rogid:WVlV2boR+rIKWZOKk7VRlJJOCfk9606 intact-crc:AFEB90BF83B4CDDA|rigid:gY8f514gNV6rc77F0saPPm7pwI4 false necessary binding region:1-91|flag tag:n-n ha tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UNQ0 uniprotkb:P11309-2 intact:EBI-1569435|uniprotkb:A0A1W3|uniprotkb:O95374|uniprotkb:Q53ZQ1|uniprotkb:Q569L4|uniprotkb:Q5YLG4|uniprotkb:Q86V64|uniprotkb:Q8IX16|uniprotkb:Q96LD6|uniprotkb:Q96TA8|uniprotkb:Q9BY73|uniprotkb:Q9NUS0|uniprotkb:Q4W5I3|uniprotkb:A8K1T5|ensembl:ENSP00000237612|ensembl:ENSP00000498246 intact:EBI-1018633|intact:EBI-20775148 psi-mi:abcg2_human(display_long)|uniprotkb:Placenta-specific ATP-binding cassette transporter(gene name synonym)|uniprotkb:Breast cancer resistance protein(gene name synonym)|uniprotkb:Mitoxantrone resistance-associated protein(gene name synonym)|uniprotkb:CDw338(gene name synonym)|uniprotkb:ABCG2(gene name)|psi-mi:ABCG2(display_short)|uniprotkb:ABCP(gene name synonym)|uniprotkb:BCRP(gene name synonym)|uniprotkb:BCRP1(gene name synonym)|uniprotkb:MXR(gene name synonym)|uniprotkb:Urate exporter(gene name synonym)|uniprotkb:ATP-binding cassette sub-family G member 2(gene name synonym) psi-mi:p11309-2(display_long)|uniprotkb:Pim-1L(isoform synonym)|uniprotkb:PIM1(gene name)|psi-mi:PIM1(display_short) psi-mi:"MI:0096"(pull down) Xie et al. (2007) pubmed:18056989|imex:IM-26546 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1569562|imex:IM-26546-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004818.2|refseq:XP_011530722.1|refseq:NP_001244315.1|refseq:XP_005263412.1|dip:DIP-29162N|ensembl:ENSG00000118777(gene)|ensembl:ENST00000237612(transcript)|ensembl:ENST00000650821(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008514"(organic anion transmembrane transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015711"(organic anion transport)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032217"(riboflavin transmembrane transporter activity)|go:"GO:0032218"(riboflavin transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046415"(urate metabolic process)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070633"(transepithelial transport)|go:"GO:0097744"(renal urate salt excretion)|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1990748"(cellular detoxification)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR030256|interpro:IPR043926|mint:Q9UNQ0|rcsb pdb:5NJ3|rcsb pdb:5NJG|rcsb pdb:6ETI|rcsb pdb:6FEQ|rcsb pdb:6FFC|rcsb pdb:6HBU|rcsb pdb:6HCO|rcsb pdb:6HIJ|rcsb pdb:6HZM|rcsb pdb:6VXF|rcsb pdb:6VXH|rcsb pdb:6VXI|rcsb pdb:6VXJ|rcsb pdb:7NEQ|rcsb pdb:7NEZ|rcsb pdb:7NFD|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2161517|reactome:R-HSA-917937 intact:EBI-696621(pim1_human)|uniprotkb:P11309-2(isoform-parent) intact:EBI-1578446(see-also) - isoform-comment:Initiates from CTG codon. figure legend:1 B|comment:The data suggest that this interaction requires both the N-terminal proline-rich region and the kinase domain present in Pim-1L but not Pim-1S.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/12/18 2018/10/22 rogid:WVlV2boR+rIKWZOKk7VRlJJOCfk9606 rogid:LMhWNRm+1/0PVcUHBDVt6kiwD149606 intact-crc:C683D618177669D2|rigid:gY8f514gNV6rc77F0saPPm7pwI4 false ha tag:n-n glutathione s tranferase tag:n-n|necessary binding region:1-91 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UNQ0 uniprotkb:P11309-2 intact:EBI-1569435|uniprotkb:A0A1W3|uniprotkb:O95374|uniprotkb:Q53ZQ1|uniprotkb:Q569L4|uniprotkb:Q5YLG4|uniprotkb:Q86V64|uniprotkb:Q8IX16|uniprotkb:Q96LD6|uniprotkb:Q96TA8|uniprotkb:Q9BY73|uniprotkb:Q9NUS0|uniprotkb:Q4W5I3|uniprotkb:A8K1T5|ensembl:ENSP00000237612|ensembl:ENSP00000498246 intact:EBI-1018633|intact:EBI-20775148 psi-mi:abcg2_human(display_long)|uniprotkb:Placenta-specific ATP-binding cassette transporter(gene name synonym)|uniprotkb:Breast cancer resistance protein(gene name synonym)|uniprotkb:Mitoxantrone resistance-associated protein(gene name synonym)|uniprotkb:CDw338(gene name synonym)|uniprotkb:ABCG2(gene name)|psi-mi:ABCG2(display_short)|uniprotkb:ABCP(gene name synonym)|uniprotkb:BCRP(gene name synonym)|uniprotkb:BCRP1(gene name synonym)|uniprotkb:MXR(gene name synonym)|uniprotkb:Urate exporter(gene name synonym)|uniprotkb:ATP-binding cassette sub-family G member 2(gene name synonym) psi-mi:p11309-2(display_long)|uniprotkb:Pim-1L(isoform synonym)|uniprotkb:PIM1(gene name)|psi-mi:PIM1(display_short) psi-mi:"MI:0663"(confocal microscopy) Xie et al. (2007) pubmed:18056989|imex:IM-26546 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1578623|imex:IM-26546-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004818.2|refseq:XP_011530722.1|refseq:NP_001244315.1|refseq:XP_005263412.1|dip:DIP-29162N|ensembl:ENSG00000118777(gene)|ensembl:ENST00000237612(transcript)|ensembl:ENST00000650821(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008514"(organic anion transmembrane transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015711"(organic anion transport)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032217"(riboflavin transmembrane transporter activity)|go:"GO:0032218"(riboflavin transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046415"(urate metabolic process)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070633"(transepithelial transport)|go:"GO:0097744"(renal urate salt excretion)|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1990748"(cellular detoxification)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR030256|interpro:IPR043926|mint:Q9UNQ0|rcsb pdb:5NJ3|rcsb pdb:5NJG|rcsb pdb:6ETI|rcsb pdb:6FEQ|rcsb pdb:6FFC|rcsb pdb:6HBU|rcsb pdb:6HCO|rcsb pdb:6HIJ|rcsb pdb:6HZM|rcsb pdb:6VXF|rcsb pdb:6VXH|rcsb pdb:6VXI|rcsb pdb:6VXJ|rcsb pdb:7NEQ|rcsb pdb:7NEZ|rcsb pdb:7NFD|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2161517|reactome:R-HSA-917937 intact:EBI-696621(pim1_human)|uniprotkb:P11309-2(isoform-parent) go:"GO:0005886"(plasma membrane) - isoform-comment:Initiates from CTG codon. figure legend:1 C|delivery method:P11309-1; Q9UNQ0 transfection|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-lncap)|taxid:9606(Human caucasian prostate carcinoma) - 2007/12/18 2018/10/30 rogid:WVlV2boR+rIKWZOKk7VRlJJOCfk9606 rogid:LMhWNRm+1/0PVcUHBDVt6kiwD149606 intact-crc:A97DDAE3EDD98491|rigid:gY8f514gNV6rc77F0saPPm7pwI4 false ha tag:n-n flag tag:n-n - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q9UNQ0 uniprotkb:P11309-2 intact:EBI-1569435|uniprotkb:A0A1W3|uniprotkb:O95374|uniprotkb:Q53ZQ1|uniprotkb:Q569L4|uniprotkb:Q5YLG4|uniprotkb:Q86V64|uniprotkb:Q8IX16|uniprotkb:Q96LD6|uniprotkb:Q96TA8|uniprotkb:Q9BY73|uniprotkb:Q9NUS0|uniprotkb:Q4W5I3|uniprotkb:A8K1T5|ensembl:ENSP00000237612|ensembl:ENSP00000498246 intact:EBI-1018633|intact:EBI-20775148 psi-mi:abcg2_human(display_long)|uniprotkb:Placenta-specific ATP-binding cassette transporter(gene name synonym)|uniprotkb:Breast cancer resistance protein(gene name synonym)|uniprotkb:Mitoxantrone resistance-associated protein(gene name synonym)|uniprotkb:CDw338(gene name synonym)|uniprotkb:ABCG2(gene name)|psi-mi:ABCG2(display_short)|uniprotkb:ABCP(gene name synonym)|uniprotkb:BCRP(gene name synonym)|uniprotkb:BCRP1(gene name synonym)|uniprotkb:MXR(gene name synonym)|uniprotkb:Urate exporter(gene name synonym)|uniprotkb:ATP-binding cassette sub-family G member 2(gene name synonym) psi-mi:p11309-2(display_long)|uniprotkb:Pim-1L(isoform synonym)|uniprotkb:PIM1(gene name)|psi-mi:PIM1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Xie et al. (2007) pubmed:18056989|imex:IM-26546 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1769824|imex:IM-26546-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004818.2|refseq:XP_011530722.1|refseq:NP_001244315.1|refseq:XP_005263412.1|dip:DIP-29162N|ensembl:ENSG00000118777(gene)|ensembl:ENST00000237612(transcript)|ensembl:ENST00000650821(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008514"(organic anion transmembrane transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015711"(organic anion transport)|go:"GO:0015878"(biotin transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032217"(riboflavin transmembrane transporter activity)|go:"GO:0032218"(riboflavin transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046415"(urate metabolic process)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070633"(transepithelial transport)|go:"GO:0097744"(renal urate salt excretion)|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1990748"(cellular detoxification)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR030256|interpro:IPR043926|mint:Q9UNQ0|rcsb pdb:5NJ3|rcsb pdb:5NJG|rcsb pdb:6ETI|rcsb pdb:6FEQ|rcsb pdb:6FFC|rcsb pdb:6HBU|rcsb pdb:6HCO|rcsb pdb:6HIJ|rcsb pdb:6HZM|rcsb pdb:6VXF|rcsb pdb:6VXH|rcsb pdb:6VXI|rcsb pdb:6VXJ|rcsb pdb:7NEQ|rcsb pdb:7NEZ|rcsb pdb:7NFD|reactome:R-HSA-189451|reactome:R-HSA-189483|reactome:R-HSA-2161517|reactome:R-HSA-917937 intact:EBI-696621(pim1_human)|uniprotkb:P11309-2(isoform-parent) omim:176807(primary-reference) - isoform-comment:Initiates from CTG codon. figure legend:1 D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-cwr_r1)|taxid:9606(Homo sapiens prostate cancer cell line CWR-R1) - 2007/12/18 2018/10/22 rogid:WVlV2boR+rIKWZOKk7VRlJJOCfk9606 rogid:LMhWNRm+1/0PVcUHBDVt6kiwD149606 intact-crc:B7323DAF2061E6C1|rigid:gY8f514gNV6rc77F0saPPm7pwI4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)