#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-1563533 uniprotkb:Q15013 - intact:EBI-712181|ensembl:ENSP00000361244|uniprotkb:B4DLV3|uniprotkb:Q6IBB1|uniprotkb:E9PAT7 psi-mi:mad2 peptide(display_short)|psi-mi:EBI-1563533(display_long) psi-mi:md2bp_human(display_long)|uniprotkb:Caught by MAD2 protein(gene name synonym)|uniprotkb:MAD2L1BP(gene name)|psi-mi:MAD2L1BP(display_short)|uniprotkb:CMT2(gene name synonym)|uniprotkb:KIAA0110(gene name synonym)|uniprotkb:"p31(comet)"(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Yang et al. (2007) imex:IM-11886|pubmed:18022368 taxid:-1(in vitro)|taxid:-1(In vitro) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1563674|wwpdb:2QYF|imex:IM-11886-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - refseq:NP_001003690.1|refseq:NP_055443.1|ensembl:ENSG00000124688(gene)|ensembl:ENST00000372171(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0031965"(nuclear membrane)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR009511(MAD2L1 binding protein)|rcsb pdb:2QYF|rcsb pdb:6F0X|dip:DIP-34492N - no-uniprot-update:An amino acid sequence which is not represented in UniProt - 3d-resolution:2.3 A|figure legend:Figs. 1B and 4, Table 1|3d-r-factors:R working 18.9%, R free 25.8%|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/12/04 2014/10/16 rogid:Gnr/ffMn7aorOlm7xJAWvqIdJfw-1 rogid:LDtsULnHHfO9LVyGU4PtVTvF/OE9606 intact-crc:4AF68E4648B02519|rigid:8PQzpJmb5FNPiTS7nq8Z/3b7e4o false - sufficient binding region:36-274 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) intact:EBI-1563533 uniprotkb:Q13257 - intact:EBI-78203|intact:EBI-28969404|ensembl:ENSP00000296509|uniprotkb:Q53F56|uniprotkb:Q548X9|uniprotkb:Q6IRW7|uniprotkb:Q8IZX3 psi-mi:mad2 peptide(display_short)|psi-mi:EBI-1563533(display_long) psi-mi:md2l1_human(display_long)|uniprotkb:MAD2L1(gene name)|psi-mi:MAD2L1(display_short)|uniprotkb:MAD2(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Yang et al. (2007) imex:IM-11886|pubmed:18022368 taxid:-1(in vitro)|taxid:-1(In vitro) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1563674|wwpdb:2QYF|imex:IM-11886-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0327"(peptide) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000164109(gene)|ensembl:ENST00000296509(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|mint:Q13257|rcsb pdb:1DUJ|rcsb pdb:1GO4|rcsb pdb:1S2H|rcsb pdb:1KLQ|rcsb pdb:2QYF|rcsb pdb:2V64|rcsb pdb:2VFX|rcsb pdb:3GMH|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6TLJ|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSP00000296509|ensembl:ENST00000333047|ensembl:ENSP00000332295|refseq:NP_002349.1|dip:DIP-29653N - no-uniprot-update:An amino acid sequence which is not represented in UniProt - 3d-resolution:2.3 A|figure legend:Figs. 1B and 4, Table 1|3d-r-factors:R working 18.9%, R free 25.8%|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/12/04 2014/10/16 rogid:Gnr/ffMn7aorOlm7xJAWvqIdJfw-1 rogid:FyL1tmJllOZ4gQvwWb96aV9PMFw9606 intact-crc:4AF68E4648B02519|rigid:8PQzpJmb5FNPiTS7nq8Z/3b7e4o false - mutation:13-13 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q13257 uniprotkb:Q15013 intact:EBI-78203|intact:EBI-28969404|ensembl:ENSP00000296509|uniprotkb:Q53F56|uniprotkb:Q548X9|uniprotkb:Q6IRW7|uniprotkb:Q8IZX3 intact:EBI-712181|ensembl:ENSP00000361244|uniprotkb:B4DLV3|uniprotkb:Q6IBB1|uniprotkb:E9PAT7 psi-mi:md2l1_human(display_long)|uniprotkb:MAD2L1(gene name)|psi-mi:MAD2L1(display_short)|uniprotkb:MAD2(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym) psi-mi:md2bp_human(display_long)|uniprotkb:Caught by MAD2 protein(gene name synonym)|uniprotkb:MAD2L1BP(gene name)|psi-mi:MAD2L1BP(display_short)|uniprotkb:CMT2(gene name synonym)|uniprotkb:KIAA0110(gene name synonym)|uniprotkb:"p31(comet)"(gene name synonym) psi-mi:"MI:0096"(pull down) Yang et al. (2007) imex:IM-11886|pubmed:18022368 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1563841|imex:IM-11886-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164109(gene)|ensembl:ENST00000296509(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|mint:Q13257|rcsb pdb:1DUJ|rcsb pdb:1GO4|rcsb pdb:1S2H|rcsb pdb:1KLQ|rcsb pdb:2QYF|rcsb pdb:2V64|rcsb pdb:2VFX|rcsb pdb:3GMH|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6TLJ|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSP00000296509|ensembl:ENST00000333047|ensembl:ENSP00000332295|refseq:NP_002349.1|dip:DIP-29653N refseq:NP_001003690.1|refseq:NP_055443.1|ensembl:ENSG00000124688(gene)|ensembl:ENST00000372171(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0031965"(nuclear membrane)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR009511(MAD2L1 binding protein)|rcsb pdb:2QYF|rcsb pdb:6F0X|dip:DIP-34492N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5A, Supp. Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/12/04 2014/10/16 rogid:FyL1tmJllOZ4gQvwWb96aV9PMFw9606 rogid:LDtsULnHHfO9LVyGU4PtVTvF/OE9606 intact-crc:7C2ED87B257F87C5|rigid:lPlBkNwBAj6yXQk3SOckR2gRL94 false mutation:13-13|glutathione s tranferase tag:?-? mutation decreasing interaction:83-83,191-191|mutation decreasing interaction:83-83|mutation decreasing interaction:191-191|35s radiolabel:?-? - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q13257 uniprotkb:Q15013 intact:EBI-78203|intact:EBI-28969404|ensembl:ENSP00000296509|uniprotkb:Q53F56|uniprotkb:Q548X9|uniprotkb:Q6IRW7|uniprotkb:Q8IZX3 intact:EBI-712181|ensembl:ENSP00000361244|uniprotkb:B4DLV3|uniprotkb:Q6IBB1|uniprotkb:E9PAT7 psi-mi:md2l1_human(display_long)|uniprotkb:MAD2L1(gene name)|psi-mi:MAD2L1(display_short)|uniprotkb:MAD2(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym) psi-mi:md2bp_human(display_long)|uniprotkb:Caught by MAD2 protein(gene name synonym)|uniprotkb:MAD2L1BP(gene name)|psi-mi:MAD2L1BP(display_short)|uniprotkb:CMT2(gene name synonym)|uniprotkb:KIAA0110(gene name synonym)|uniprotkb:"p31(comet)"(gene name synonym) psi-mi:"MI:0096"(pull down) Yang et al. (2007) imex:IM-11886|pubmed:18022368 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1637675|imex:IM-11886-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164109(gene)|ensembl:ENST00000296509(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|mint:Q13257|rcsb pdb:1DUJ|rcsb pdb:1GO4|rcsb pdb:1S2H|rcsb pdb:1KLQ|rcsb pdb:2QYF|rcsb pdb:2V64|rcsb pdb:2VFX|rcsb pdb:3GMH|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6TLJ|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSP00000296509|ensembl:ENST00000333047|ensembl:ENSP00000332295|refseq:NP_002349.1|dip:DIP-29653N refseq:NP_001003690.1|refseq:NP_055443.1|ensembl:ENSG00000124688(gene)|ensembl:ENST00000372171(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0031965"(nuclear membrane)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR009511(MAD2L1 binding protein)|rcsb pdb:2QYF|rcsb pdb:6F0X|dip:DIP-34492N psi-mi:"MI:0469"(intact) - - figure legend:Supp. Fig. 4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/12/04 2014/10/16 rogid:FyL1tmJllOZ4gQvwWb96aV9PMFw9606 rogid:LDtsULnHHfO9LVyGU4PtVTvF/OE9606 intact-crc:3F6C2BD4364810F8|rigid:lPlBkNwBAj6yXQk3SOckR2gRL94 false glutathione s tranferase tag:?-?|mutation decreasing interaction:133-133|mutation decreasing interaction:141-141|mutation decreasing interaction:184-184 - - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography) uniprotkb:Q13257 uniprotkb:Q15013 intact:EBI-78203|intact:EBI-28969404|ensembl:ENSP00000296509|uniprotkb:Q53F56|uniprotkb:Q548X9|uniprotkb:Q6IRW7|uniprotkb:Q8IZX3 intact:EBI-712181|ensembl:ENSP00000361244|uniprotkb:B4DLV3|uniprotkb:Q6IBB1|uniprotkb:E9PAT7 psi-mi:md2l1_human(display_long)|uniprotkb:MAD2L1(gene name)|psi-mi:MAD2L1(display_short)|uniprotkb:MAD2(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym) psi-mi:md2bp_human(display_long)|uniprotkb:Caught by MAD2 protein(gene name synonym)|uniprotkb:MAD2L1BP(gene name)|psi-mi:MAD2L1BP(display_short)|uniprotkb:CMT2(gene name synonym)|uniprotkb:KIAA0110(gene name synonym)|uniprotkb:"p31(comet)"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yang et al. (2007) imex:IM-11886|pubmed:18022368 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1563900|imex:IM-11886-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164109(gene)|ensembl:ENST00000296509(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|mint:Q13257|rcsb pdb:1DUJ|rcsb pdb:1GO4|rcsb pdb:1S2H|rcsb pdb:1KLQ|rcsb pdb:2QYF|rcsb pdb:2V64|rcsb pdb:2VFX|rcsb pdb:3GMH|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6TLJ|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSP00000296509|ensembl:ENST00000333047|ensembl:ENSP00000332295|refseq:NP_002349.1|dip:DIP-29653N refseq:NP_001003690.1|refseq:NP_055443.1|ensembl:ENSG00000124688(gene)|ensembl:ENST00000372171(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0031965"(nuclear membrane)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR009511(MAD2L1 binding protein)|rcsb pdb:2QYF|rcsb pdb:6F0X|dip:DIP-34492N psi-mi:"MI:0469"(intact) - - figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2007/12/04 2014/10/16 rogid:FyL1tmJllOZ4gQvwWb96aV9PMFw9606 rogid:LDtsULnHHfO9LVyGU4PtVTvF/OE9606 intact-crc:779A28F7B34C543D|rigid:lPlBkNwBAj6yXQk3SOckR2gRL94 false - myc tag:?-?|mutation decreasing interaction:83-83,191-191 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q13257 uniprotkb:Q15013 intact:EBI-78203|intact:EBI-28969404|ensembl:ENSP00000296509|uniprotkb:Q53F56|uniprotkb:Q548X9|uniprotkb:Q6IRW7|uniprotkb:Q8IZX3 intact:EBI-712181|ensembl:ENSP00000361244|uniprotkb:B4DLV3|uniprotkb:Q6IBB1|uniprotkb:E9PAT7 psi-mi:md2l1_human(display_long)|uniprotkb:MAD2L1(gene name)|psi-mi:MAD2L1(display_short)|uniprotkb:MAD2(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym) psi-mi:md2bp_human(display_long)|uniprotkb:Caught by MAD2 protein(gene name synonym)|uniprotkb:MAD2L1BP(gene name)|psi-mi:MAD2L1BP(display_short)|uniprotkb:CMT2(gene name synonym)|uniprotkb:KIAA0110(gene name synonym)|uniprotkb:"p31(comet)"(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Yang et al. (2007) imex:IM-11886|pubmed:18022368 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1563949|imex:IM-11886-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000164109(gene)|ensembl:ENST00000296509(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|mint:Q13257|rcsb pdb:1DUJ|rcsb pdb:1GO4|rcsb pdb:1S2H|rcsb pdb:1KLQ|rcsb pdb:2QYF|rcsb pdb:2V64|rcsb pdb:2VFX|rcsb pdb:3GMH|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6TLJ|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSP00000296509|ensembl:ENST00000333047|ensembl:ENSP00000332295|refseq:NP_002349.1|dip:DIP-29653N refseq:NP_001003690.1|refseq:NP_055443.1|ensembl:ENSG00000124688(gene)|ensembl:ENST00000372171(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0031965"(nuclear membrane)|go:"GO:1902426"(deactivation of mitotic spindle assembly checkpoint)|interpro:IPR009511(MAD2L1 binding protein)|rcsb pdb:2QYF|rcsb pdb:6F0X|dip:DIP-34492N psi-mi:"MI:0469"(intact) - - figure legend:Supp Fig 2C|complex-properties:calculated molecular mass = 51 kD.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/12/04 2014/10/16 rogid:FyL1tmJllOZ4gQvwWb96aV9PMFw9606 rogid:LDtsULnHHfO9LVyGU4PtVTvF/OE9606 intact-crc:84CEB6AD5C806F85|rigid:lPlBkNwBAj6yXQk3SOckR2gRL94 false mutation:13-13 sufficient binding region:36-274 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)