#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9VA38	uniprotkb:Q45VV3	intact:EBI-82717|ensemblmetazoa:FBpp0085082	intact:EBI-141254|uniprotkb:Q9W1B6|uniprotkb:A2RVH0|uniprotkb:A2RVH4|uniprotkb:Q0E8X1|uniprotkb:Q7KVG6|ensemblmetazoa:FBpp0288697|ensemblmetazoa:FBpp0301274|intact:EBI-2480586|uniprotkb:Q95TU5	psi-mi:warts_drome(display_long)|uniprotkb:wts(gene name)|psi-mi:wts(display_short)|uniprotkb:CG12072(orf name)	psi-mi:yap1_drome(display_long)|uniprotkb:yki(gene name)|psi-mi:yki(display_short)|uniprotkb:Protein yorkie(gene name synonym)|uniprotkb:Transcriptional coactivator YAP1 homolog(gene name synonym)|uniprotkb:CG4005(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Dong et al. (2007)	imex:IM-11870|pubmed:17889654	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1554679|imex:IM-11870-2	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblmetazoa:FBgn0011739(gene)|ensemblmetazoa:FBtr0085720(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001708"(cell fate specification)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007424"(open tracheal system development)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120080"(obsolete negative regulation of microfilament motor activity)|go:"GO:1904504"(positive regulation of lipophagy)|interpro:IPR000719(Protein kinase, core)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0043065"(positive regulation of apoptotic process)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028742|reactome:R-DME-2028269|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0045571"(negative regulation of imaginal disc growth)|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150|reactome:R-DME-390178|reactome:R-DME-451806|refseq:NP_733403.1|flybase:FBgn0011739|dip:DIP-20374N	refseq:NP_001036568.2|refseq:NP_611879.4|flybase:FBgn0034970|ensemblmetazoa:FBgn0034970(gene)|ensemblmetazoa:FBtr0290258(transcript)|ensemblmetazoa:FBtr0309372(transcript)|go:"GO:0001708"(cell fate specification)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019900"(kinase binding)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0035329"(hippo signaling)|go:"GO:0040008"(regulation of growth)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0090210"(regulation of establishment of blood-brain barrier)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1905437"(positive regulation of histone H3-K4 trimethylation)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-DME-1251985|reactome:R-DME-2028269|reactome:R-DME-2032785|reactome:R-DME-2173796|reactome:R-DME-390098|reactome:R-DME-390193|reactome:R-DME-451806|reactome:R-DME-8939236|reactome:R-DME-8951671|refseq:NP_726414.3	go:"GO:0004672"(protein kinase activity)|go:"GO:0006468"(protein phosphorylation)	-	-	resulting-ptm:Phosphorylation of Yki on Ser-168|figure legend:Figure 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/13	2014/10/16	rogid:yBO+BhKuFTQXEj2ywUMv0/brvMw7227	rogid:XRXB3wMsUcluStu33RaFw7JVf1k7227	intact-crc:741ED58B45461CA2|rigid:k5Q+SQsBx0ZPhbVhgixBRNRlltk	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P29310	uniprotkb:Q45VV3	intact:EBI-198100|intact:EBI-1630797|uniprotkb:A4UZB2|uniprotkb:A4UZB3|uniprotkb:O01665|uniprotkb:Q0E9D5|uniprotkb:Q0E9D6|uniprotkb:Q0E9D7|uniprotkb:Q8IGB9|uniprotkb:Q8MKV5|uniprotkb:Q9V5G6|uniprotkb:C1C593|uniprotkb:C9QP27|ensemblmetazoa:FBpp0087502|ensemblmetazoa:FBpp0087503|ensemblmetazoa:FBpp0099540|ensemblmetazoa:FBpp0305136|ensemblmetazoa:FBpp0305137	intact:EBI-141254|uniprotkb:Q9W1B6|uniprotkb:A2RVH0|uniprotkb:A2RVH4|uniprotkb:Q0E8X1|uniprotkb:Q7KVG6|ensemblmetazoa:FBpp0288697|ensemblmetazoa:FBpp0301274|intact:EBI-2480586|uniprotkb:Q95TU5	psi-mi:1433z_drome(display_long)|uniprotkb:14-3-3zeta(gene name)|psi-mi:14-3-3zeta(display_short)|uniprotkb:14-3-3EZ(gene name synonym)|uniprotkb:leo(gene name synonym)|uniprotkb:14-3-3(gene name synonym)|uniprotkb:THAP(gene name synonym)|uniprotkb:CG17870(orf name)|uniprotkb:14-3-3-like protein(gene name synonym)|uniprotkb:Protein Leonardo(gene name synonym)	psi-mi:yap1_drome(display_long)|uniprotkb:yki(gene name)|psi-mi:yki(display_short)|uniprotkb:Protein yorkie(gene name synonym)|uniprotkb:Transcriptional coactivator YAP1 homolog(gene name synonym)|uniprotkb:CG4005(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Dong et al. (2007)	imex:IM-11870|pubmed:17889654	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1607088|imex:IM-11870-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001260845.1|refseq:NP_001260846.1|refseq:NP_001014515.1|refseq:NP_001014516.1|refseq:NP_476885.2|refseq:NP_724884.1|refseq:NP_724885.1|refseq:NP_724886.1|refseq:NP_724887.2|refseq:NP_724888.2|refseq:NP_724889.2|refseq:NP_995792.1|flybase:FBgn0004907|dip:DIP-17371N|ensemblmetazoa:FBgn0004907(gene)|ensemblmetazoa:FBtr0088414(transcript)|ensemblmetazoa:FBtr0088415(transcript)|ensemblmetazoa:FBtr0100183(transcript)|ensemblmetazoa:FBtr0332916(transcript)|ensemblmetazoa:FBtr0332917(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007294"(germarium-derived oocyte fate determination)|go:"GO:0007399"(nervous system development)|go:"GO:0007611"(learning or memory)|go:"GO:0008103"(oocyte microtubule cytoskeleton polarization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0045172"(germline ring canal)|go:"GO:0045448"(mitotic cell cycle, embryonic)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0120176"(positive regulation of torso signaling pathway)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|reactome:R-DME-165159|reactome:R-DME-166208|reactome:R-DME-170968|reactome:R-DME-2028269|reactome:R-DME-3769402|reactome:R-DME-390098|reactome:R-DME-392517|reactome:R-DME-430116|reactome:R-DME-450385|reactome:R-DME-450513|reactome:R-DME-450604|reactome:R-DME-5625740|reactome:R-DME-5628897|reactome:R-DME-5673000|reactome:R-DME-5674135|reactome:R-DME-5675221|reactome:R-DME-6804114|reactome:R-DME-75035|reactome:R-DME-9013700|reactome:R-DME-9614399	refseq:NP_001036568.2|refseq:NP_611879.4|flybase:FBgn0034970|ensemblmetazoa:FBgn0034970(gene)|ensemblmetazoa:FBtr0290258(transcript)|ensemblmetazoa:FBtr0309372(transcript)|go:"GO:0001708"(cell fate specification)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019900"(kinase binding)|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0035329"(hippo signaling)|go:"GO:0040008"(regulation of growth)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0090210"(regulation of establishment of blood-brain barrier)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097575"(lateral cell cortex)|go:"GO:0045572"(positive regulation of imaginal disc growth)|go:"GO:0120081"(obsolete positive regulation of microfilament motor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1905437"(positive regulation of histone H3-K4 trimethylation)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|reactome:R-DME-1251985|reactome:R-DME-2028269|reactome:R-DME-2032785|reactome:R-DME-2173796|reactome:R-DME-390098|reactome:R-DME-390193|reactome:R-DME-451806|reactome:R-DME-8939236|reactome:R-DME-8951671|refseq:NP_726414.3	psi-mi:"MI:0469"(intact)	-	-	comment:Requires presence of components of the Hippo signalling pathway for interaction to occur.|figure legend:Figure 1C|delivery method:Q95TU5 transfection|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2007/11/13	2014/10/16	rogid:G1jZJfZZqZwEu9lekPYYdvZAXO87227	rogid:XRXB3wMsUcluStu33RaFw7JVf1k7227	intact-crc:0EF5C3685723EB98|rigid:gyl9XnKxAMkkedLDk0eMdRIcnM4	false	-	ha tag:?-?|mutation decreasing interaction:145-145	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)