#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-1173115	uniprotkb:Q9H160	-	intact:EBI-389787|uniprotkb:O95698|uniprotkb:B6ZDS1|ensembl:ENSP00000307183	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:ing2_human(display_long)|uniprotkb:ING2(gene name)|psi-mi:ING2(display_short)|uniprotkb:p33ING2(gene name synonym)|uniprotkb:Inhibitor of growth 1-like protein(gene name synonym)|uniprotkb:p32(gene name synonym)|uniprotkb:ING1L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001278888.1|refseq:NP_001555.1|ensembl:ENSG00000168556(gene)|ensembl:ENST00000302327(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007141"(male meiosis I)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028639|interpro:IPR028651|interpro:IPR042019|mint:Q9H160|reactome:R-HSA-3899300|reactome:R-HSA-6811555	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:chmce0rTv1IxOey+rTUF085Gdgg9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:Q96PU4	-	intact:EBI-625304|uniprotkb:Q5VYR1|uniprotkb:Q5VYR3|uniprotkb:Q659C8|uniprotkb:Q8TAG7|ensembl:ENSP00000276893	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:uhrf2_human(display_long)|uniprotkb:Ubiquitin-like PHD and RING finger domain-containing protein 2(gene name synonym)|uniprotkb:Ubiquitin-like-containing PHD and RING finger domains protein 2(gene name synonym)|uniprotkb:Np95/ICBP90-like RING finger protein(gene name synonym)|uniprotkb:Nuclear zinc finger protein Np97(gene name synonym)|uniprotkb:RING finger protein 107(gene name synonym)|uniprotkb:UHRF2(gene name)|psi-mi:UHRF2(display_short)|uniprotkb:NIRF(gene name synonym)|uniprotkb:RNF107(gene name synonym)|uniprotkb:Nuclear protein 97(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UHRF2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_690856.1|ensembl:ENSG00000147854(gene)|ensembl:ENST00000276893(transcript)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003105(SRA-YDG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015947(PUA-like)|interpro:IPR017907|interpro:IPR019787|interpro:IPR021991|interpro:IPR029071|interpro:IPR036987|rcsb pdb:1WY8|rcsb pdb:1Z6U|rcsb pdb:2E6S|rcsb pdb:3OLN|rcsb pdb:4PW5|rcsb pdb:4PW6|rcsb pdb:4PW7|rcsb pdb:4TVR|rcsb pdb:5YCO|reactome:R-HSA-3899300|interpro:IPR001841(Zinc finger, RING-type)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0007049"(cell cycle)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000626(Ubiquitin)	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:zXJPI7UvOPWn2fsgF5/RdIUMc749606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:Q9UK53	-	intact:EBI-399198|uniprotkb:O00532|uniprotkb:O43658|uniprotkb:Q9H007|uniprotkb:Q9HD98|uniprotkb:Q9HD99|uniprotkb:Q9NS83|uniprotkb:Q9P0U6|uniprotkb:Q9UBC6|uniprotkb:Q9UIJ1|uniprotkb:Q9UIJ2|uniprotkb:Q9UIJ3|uniprotkb:Q9UIJ4|uniprotkb:Q9UK52|uniprotkb:Q53ZR3|uniprotkb:Q5T9H0|uniprotkb:Q5T9G8|uniprotkb:Q5T9H1|uniprotkb:Q5T9G9	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:ing1_human(display_long)|uniprotkb:ING1(gene name)|psi-mi:ING1(display_short)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_937860.1|refseq:NP_937861.1|refseq:NP_937862.1|refseq:NP_001254657.1|mint:Q9UK53|refseq:NP_005528.4|dip:DIP-24256N|dip:DIP-24257N|dip:DIP-24258N|interpro:IPR019786|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR024610|interpro:IPR028643|interpro:IPR028651|rcsb pdb:2QIC|go:"GO:0005634"(nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010941"(regulation of cell death)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:AQtE1tLKo5QG/aU6spQzOR5AjLw9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:P29375	-	intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:Q9UPP1	-	intact:EBI-1560800|uniprotkb:Q5H9U5|uniprotkb:Q5VUJ4|uniprotkb:Q7Z6D4|uniprotkb:Q9HAH2|uniprotkb:Q5JPS0|uniprotkb:Q5JPS2|uniprotkb:Q5JPS3|uniprotkb:B7Z911|uniprotkb:Q5JPR9|uniprotkb:B3KMV4|ensembl:ENSP00000350676	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:phf8_human(display_long)|uniprotkb:PHF8(gene name)|psi-mi:PHF8(display_short)|uniprotkb:KIAA1111(gene name synonym)|uniprotkb:ZNF422(gene name synonym)|uniprotkb:PHD finger protein 8(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(36) demethylase PHF8"(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase PHF8"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001171825.1|refseq:NP_001171826.1|refseq:NP_055922.1|refseq:XP_016884851.1|dip:DIP-38913N|ensembl:ENSG00000172943(gene)|ensembl:ENST00000357988(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035574"(histone H4-K20 demethylation)|go:"GO:0035575"(histone H4-methyl-lysine-20 demethylase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0061188"(negative regulation of ribosomal DNA heterochromatin assembly)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR041070|rcsb pdb:2WWU|rcsb pdb:3K3N|rcsb pdb:3K3O|rcsb pdb:3KV4|rcsb pdb:4DO0|rcsb pdb:7CMZ|reactome:R-HSA-2299718|reactome:R-HSA-3214842	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:/HpV11qoBcuj2YCa2dQWuo9moCk9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:O14646	-	intact:EBI-1560858|uniprotkb:Q17RZ3|ensembl:ENSP00000284049|ensembl:ENSP00000483667	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:chd1_human(display_long)|uniprotkb:ATP-dependent helicase CHD1(gene name synonym)|uniprotkb:CHD1(gene name)|psi-mi:CHD1(display_short)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001261.2|refseq:XP_005271924.1|dip:DIP-38922N|ensembl:ENSG00000153922(gene)|ensembl:ENST00000284049(transcript)|ensembl:ENST00000614616(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR025260|interpro:IPR027417|interpro:IPR038718|interpro:IPR040793|mint:O14646|rcsb pdb:2B2T|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2B2Y|rcsb pdb:2N39|rcsb pdb:4B4C|rcsb pdb:4NW2|rcsb pdb:4O42|rcsb pdb:5AFW|reactome:R-HSA-9018519	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:KzH9c8MyoQh0Ph+KwSUktSa5qWM9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:Q6P1X5	-	intact:EBI-1560063|uniprotkb:O43487|uniprotkb:O43604|uniprotkb:O60668|uniprotkb:Q86WW7|uniprotkb:Q8IWK4|uniprotkb:B2RE82|ensembl:ENSP00000367406	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf2_human(display_long)|uniprotkb:Transcription initiation factor TFIID 150 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 150 kDa(gene name synonym)|uniprotkb:150 kDa cofactor of initiator function(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit B(gene name synonym)|uniprotkb:TAF2(gene name)|psi-mi:TAF2(display_short)|uniprotkb:CIF150(gene name synonym)|uniprotkb:TAF2B(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003175.1|dip:DIP-38921N|ensembl:ENSG00000064313(gene)|ensembl:ENST00000378164(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0033276"(transcription factor TFTC complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027268|interpro:IPR037813|interpro:IPR042097|mint:Q6P1X5|rcsb pdb:5FUR|rcsb pdb:6MZC|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:3MPkpqVRwuY2SiUxjQkcRFlq1RM9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:Q12962	-	intact:EBI-708376|uniprotkb:O00703|uniprotkb:Q13175|uniprotkb:Q6FH13|ensembl:ENSP00000299424	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf10_human(display_long)|uniprotkb:Transcription initiation factor TFIID 30 kDa subunit(gene name synonym)|uniprotkb:STAF28(gene name synonym)|uniprotkb:TAF10(gene name)|psi-mi:TAF10(display_short)|uniprotkb:TAF2H(gene name synonym)|uniprotkb:TAFII30(gene name synonym)|uniprotkb:TAF2A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_006275.1|dip:DIP-297N|ensembl:ENSG00000166337(gene)|ensembl:ENST00000299424(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0034622"|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR003923(Transcription initiation factor TFIID, 23-30 kDa subunit)|mint:Q12962|rcsb pdb:2F69|rcsb pdb:3M53|rcsb pdb:3M54|rcsb pdb:3M55|rcsb pdb:3M56|rcsb pdb:3M57|rcsb pdb:3M58|rcsb pdb:3M59|rcsb pdb:3M5A|rcsb pdb:4J7F|rcsb pdb:4J7I|rcsb pdb:4J83|rcsb pdb:4J8O|rcsb pdb:4WV4|rcsb pdb:5EG2|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-3214847|reactome:R-HSA-5689880|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:8HFLtF8faq1WlDk5+r4B/+4Ldeg9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:P49848	-	intact:EBI-1560206|uniprotkb:A4D2B2|uniprotkb:A4D2B3|uniprotkb:Q6AI29|uniprotkb:D6W5U2|uniprotkb:B4DT11|ensembl:ENSP00000344537|ensembl:ENSP00000389575|ensembl:ENSP00000416396	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf6_human(display_long)|uniprotkb:Transcription initiation factor TFIID 70 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 80 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit E(gene name synonym)|uniprotkb:TAF6(gene name)|psi-mi:TAF6(display_short)|uniprotkb:TAF2E(gene name synonym)|uniprotkb:TAFII70(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:XP_006716163.1|refseq:NP_005632.1|refseq:NP_647476.1|refseq:NP_001177344.1|dip:DIP-773N|ensembl:ENSG00000106290(gene)|ensembl:ENST00000344095(transcript)|ensembl:ENST00000452041(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005829"(cytosol)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0071339"(MLL1 complex)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR011442(Protein of unknown function DUF1546)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037796|rcsb pdb:5FUR|rcsb pdb:6F3T|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|ensembl:ENST00000453269(transcript)	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:oGsdH9+tG2BXsR+jr7hBuCCAS809606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:Q15542	-	intact:EBI-1560145|uniprotkb:Q53EM4|uniprotkb:Q5SYD5|uniprotkb:Q86UZ7|uniprotkb:Q9Y4K5|uniprotkb:A8K5B4|uniprotkb:B2RMR0|uniprotkb:B7ZKJ6|ensembl:ENSP00000358854	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf5_human(display_long)|uniprotkb:Transcription initiation factor TFIID 100 kDa subunit(gene name synonym)|uniprotkb:TAF5(gene name)|psi-mi:TAF5(display_short)|uniprotkb:TAF2D(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_008882.2|refseq:NP_620640.1|dip:DIP-28150N|ensembl:ENSG00000148835(gene)|ensembl:ENST00000369839(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007582(WD40 associated region in TFIID subunit)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037264|interpro:IPR037783|rcsb pdb:2NXP|rcsb pdb:6F3T|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:PKpggshlmaWo83aeQNxZ4PDb1Eo9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:Q5VWG9	-	intact:EBI-1560087|uniprotkb:Q6GMS5|uniprotkb:Q6P6B5|uniprotkb:Q86VY6|uniprotkb:Q9BQS9|uniprotkb:Q9UFI8|uniprotkb:Q05DA0|ensembl:ENSP00000340271	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf3_human(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:TAF3(gene name)|psi-mi:TAF3(display_short)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_114129.1|dip:DIP-38920N|ensembl:ENST00000344293(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|rcsb pdb:5C13|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5XMY|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|ensembl:ENSG00000165632(gene)	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:AYHavgdmdOeGnBuVoI7NDdVWKTY9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:O00268	-	intact:EBI-1034261|uniprotkb:A6NGD9|uniprotkb:Q5TBP6|uniprotkb:Q99721|uniprotkb:Q9BR40|uniprotkb:Q9BX42|intact:EBI-28988369|ensembl:ENSP00000252996	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf4_human(display_long)|uniprotkb:TAF4(gene name)|psi-mi:TAF4(display_short)|uniprotkb:TAF2C(gene name synonym)|uniprotkb:TAF2C1(gene name synonym)|uniprotkb:TAF4A(gene name synonym)|uniprotkb:TAFII130(gene name synonym)|uniprotkb:TAFII135(gene name synonym)|uniprotkb:TBP-associated factor 4(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 135 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 130 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit C(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_003176.2|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|ensembl:ENSG00000130699(gene)|ensembl:ENST00000252996(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005829"(cytosol)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR007900(Transcription initiation factor TFIID component TAF4)|interpro:IPR009072(Histone-fold)|interpro:IPR037249|mint:O00268|rcsb pdb:1H3O|rcsb pdb:2P6V|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|ensembl:ENSP00000252996|dip:DIP-35350N	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:gnLBL5GavMLTOKfnt0Gdu2aYMqM9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:P20226	-	intact:EBI-355371|uniprotkb:Q16845|uniprotkb:Q9UC02|intact:EBI-1056192|uniprotkb:Q6IBM6|ensembl:ENSP00000230354|ensembl:ENSP00000375942|intact:EBI-11019728|uniprotkb:B4E3B3|uniprotkb:F5H869	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:tbp_human(display_long)|uniprotkb:TBP(gene name)|psi-mi:TBP(display_short)|uniprotkb:TF2D(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:GTF2D1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001165556.1|refseq:NP_003185.1|ensembl:ENSP00000230354|ensembl:ENSP00000375942|ensembl:ENST00000540980|ensembl:ENSP00000442132|ensembl:ENSG00000112592(gene)|ensembl:ENST00000230354(transcript)|ensembl:ENST00000392092(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|mint:P20226|rcsb pdb:1C9B|rcsb pdb:1CDW|rcsb pdb:1JFI|rcsb pdb:1NVP|rcsb pdb:1TGH|rcsb pdb:4ROC|rcsb pdb:4ROD|rcsb pdb:4ROE|rcsb pdb:5FUR|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5N9G|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-427359|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-9018519|dip:DIP-1078N	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:tH4ckPOwO4Icr1YsnJ1Ck/6Cgmo9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:Q15544	-	intact:EBI-1027005|uniprotkb:Q9UHS0|uniprotkb:B2R8R3|ensembl:ENSP00000354633|uniprotkb:B4DY18	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf11_human(display_long)|uniprotkb:TAF11(gene name)|psi-mi:TAF11(display_short)|uniprotkb:TAF2I(gene name synonym)|uniprotkb:PRO2134(orf name)|uniprotkb:Transcription initiation factor TFIID 28 kDa subunit(gene name synonym)|uniprotkb:TFIID subunit p30-beta(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005634.1|ensembl:ENSG00000064995(gene)|ensembl:ENST00000361288(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|interpro:IPR006809(TAFII28-like protein)|interpro:IPR009072(Histone-fold)|rcsb pdb:1BH8|rcsb pdb:1BH9|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|refseq:NP_001257417.1|dip:DIP-495N	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:bpvaKWTrUJbJ/klBA/j4DHYRbMg9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:Q12830	-	intact:EBI-1560273|uniprotkb:Q6NX67|uniprotkb:Q7Z7D6|uniprotkb:Q9UIG2|ensembl:ENSP00000315454	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:bptf_human(display_long)|uniprotkb:Bromodomain and PHD finger-containing transcription factor(gene name synonym)|uniprotkb:Fetal Alzheimer antigen(gene name synonym)|uniprotkb:Fetal Alz-50 clone 1 protein(gene name synonym)|uniprotkb:BPTF(gene name)|psi-mi:BPTF(display_short)|uniprotkb:FAC1(gene name synonym)|uniprotkb:FALZ(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_004450.3|refseq:NP_872579.2|dip:DIP-38919N|ensembl:ENSG00000171634(gene)|ensembl:ENST00000321892(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0009611"(response to wounding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016589"(NURF complex)|go:"GO:0030425"(dendrite)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044297"(cell body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019786|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR038028|mint:Q12830|rcsb pdb:2F6J|rcsb pdb:2F6N|rcsb pdb:2FSA|rcsb pdb:2FUI|rcsb pdb:2FUU|rcsb pdb:2RI7|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3UV2|rcsb pdb:5H6Y|rcsb pdb:5R4G|rcsb pdb:5R4H|rcsb pdb:5R4I|rcsb pdb:5R4J|rcsb pdb:5R4K|rcsb pdb:5R4L|rcsb pdb:5R4M|rcsb pdb:5R4N|rcsb pdb:5R4O|rcsb pdb:6AZE|rcsb pdb:7K6R|rcsb pdb:7K6S|rcsb pdb:7KDW|rcsb pdb:7KDZ	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:QQehqJ6NUFT7JEUOto64C73imBY9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:Q7Z7C8	-	intact:EBI-1560220|uniprotkb:Q8N4R9|uniprotkb:Q96M52|uniprotkb:Q5T0K1|ensembl:ENSP00000362068	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf8_human(display_long)|uniprotkb:TBN(gene name synonym)|uniprotkb:TBP-associated factor 8(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 43 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 43 kDa(gene name synonym)|uniprotkb:Protein taube nuss(gene name synonym)|uniprotkb:TAF8(gene name)|psi-mi:TAF8(display_short)|uniprotkb:TAFII43(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_612639.2|refseq:XP_011512598.1|dip:DIP-60591N|ensembl:ENSG00000137413(gene)|ensembl:ENST00000372977(transcript)|go:"GO:0001112"(DNA-templated transcription open complex formation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051457"(maintenance of protein location in nucleus)|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR019473|interpro:IPR037818|rcsb pdb:4WV4|rcsb pdb:4WV6|rcsb pdb:5FUR|rcsb pdb:6MZC|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGG|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-6807505|rcsb pdb:7EGE	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:WMGuVWGlsQ60hS5qzNqGojl7rAo9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:Q92750	-	intact:EBI-1560111|uniprotkb:Q29YA4|uniprotkb:Q29YA5|ensembl:ENSP00000269142	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf4b_human(display_long)|uniprotkb:Transcription initiation factor TFIID 105 kDa subunit(gene name synonym)|uniprotkb:TAF4B(gene name)|psi-mi:TAF4B(display_short)|uniprotkb:TAF2C2(gene name synonym)|uniprotkb:TAFII105(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005631.1|refseq:NP_001280654.1|ensembl:ENSG00000141384(gene)|ensembl:ENST00000269142(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0051059"(NF-kappaB binding)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR007900(Transcription initiation factor TFIID component TAF4)|interpro:IPR009072(Histone-fold)|interpro:IPR037249|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:Su6O6Yx9/bvXYqygo2HKWtD4syg9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:Q16514	-	intact:EBI-1034238|uniprotkb:Q15775|uniprotkb:Q5T077|uniprotkb:D3DPM5|ensembl:ENSP00000263974|ensembl:ENSP00000362930	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf12_human(display_long)|uniprotkb:TAF12(gene name)|psi-mi:TAF12(display_short)|uniprotkb:TAF15(gene name synonym)|uniprotkb:TAF2J(gene name synonym)|uniprotkb:TAFII20(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 20/15 kDa subunits(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001128690.1|refseq:NP_005635.1|ensembl:ENSG00000120656(gene)|ensembl:ENST00000263974(transcript)|ensembl:ENST00000373824(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003228(Transcription initiation factor TFIID)|interpro:IPR009072(Histone-fold)|interpro:IPR037794|mint:Q16514|rcsb pdb:1H3O|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-3214847|dip:DIP-496N	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:nzWJez/7zwBDPSEGXSPgCO46nng9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:Q15543	-	intact:EBI-1026992|uniprotkb:Q5TYV6|uniprotkb:B2R5E5|ensembl:ENSP00000355051|ensembl:ENSP00000433883	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf13_human(display_long)|uniprotkb:TAF13(gene name)|psi-mi:TAF13(display_short)|uniprotkb:TAF2K(gene name synonym)|uniprotkb:TAFII18(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 18 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005636.1|ensembl:ENSG00000197780(gene)|ensembl:ENST00000338366(transcript)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|ensembl:ENST00000461096(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003195(Transcription initiation factor IID, 18 kDa subunit)|interpro:IPR009072(Histone-fold)|rcsb pdb:1BH8|rcsb pdb:1BH9|go:"GO:0005654"(nucleoplasm)|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:7EDX|rcsb pdb:7EG7|go:"GO:0005669"(transcription factor TFIID complex)|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|go:"GO:0005730"(nucleolus)|rcsb pdb:7EGB|rcsb pdb:7EGC|go:"GO:0006352"(DNA-templated transcription, initiation)|rcsb pdb:7EGD|rcsb pdb:7EGE|go:"GO:0006366"(transcription by RNA polymerase II)|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|dip:DIP-900N	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:7pXO1SLH76kWulpTOtxekJGU8ac9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:Q9HBM6	-	intact:EBI-751601|uniprotkb:Q9Y2S3|uniprotkb:B2RUZ9|ensembl:ENSP00000339917	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf9b_human(display_long)|uniprotkb:Transcription initiation factor TFIID subunit 9-like(gene name synonym)|uniprotkb:Transcription-associated factor TAFII31L(gene name synonym)|uniprotkb:Neuronal cell death-related protein 7(gene name synonym)|uniprotkb:TAF9B(gene name)|psi-mi:TAF9B(display_short)|uniprotkb:TAF9L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_057059.2|ensembl:ENSG00000187325(gene)|ensembl:ENST00000341864(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|mint:Q9HBM6|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-5689880|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:8+i5lmcx4OcgCEbk2F9MS8bYhos9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:Q53T94	-	intact:EBI-1560239|uniprotkb:Q15574|uniprotkb:Q8WVC3|uniprotkb:B4DI42|uniprotkb:F8WD72|ensembl:ENSP00000263663	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf1b_human(display_long)|uniprotkb:TATA box-binding protein-associated factor 1B(gene name synonym)|uniprotkb:Transcription initiation factor SL1/TIF-IB subunit B(gene name synonym)|uniprotkb:RNA polymerase I-specific TBP-associated factor 63 kDa(gene name synonym)|uniprotkb:TAF1B(gene name)|psi-mi:TAF1B(display_short)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005671.2|refseq:NP_001305905.1|ensembl:ENSG00000115750(gene)|ensembl:ENST00000263663(transcript)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005668"(RNA polymerase transcription factor SL1 complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|go:"GO:0046872"(metal ion binding)|go:"GO:0070860"(RNA polymerase I core factor complex)|interpro:IPR021752|interpro:IPR033599|mint:Q53T94|reactome:R-HSA-427359|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73863	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:nYrFuCrXHEM0PC8bF8G5OjDiiT49606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:Q15545	-	intact:EBI-1560194|uniprotkb:Q13036|uniprotkb:B2RBV9|ensembl:ENSP00000312709	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf7_human(display_long)|uniprotkb:Transcription initiation factor TFIID 55 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit F(gene name synonym)|uniprotkb:TAF7(gene name)|psi-mi:TAF7(display_short)|uniprotkb:TAF2F(gene name synonym)|uniprotkb:TAFII55(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005633.2|dip:DIP-29047N|ensembl:ENSG00000178913(gene)|ensembl:ENST00000313368(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000296"(spermine transport)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045344"(negative regulation of MHC class I biosynthetic process)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0106140"(P-TEFb complex binding)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|rcsb pdb:4RGW|rcsb pdb:5FUR|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:FFk04k421YC/B0n/5GXpDK9uhBU9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:Q16594	-	intact:EBI-712521|ensembl:ENSP00000370193|ensembl:ENSP00000421873|ensembl:ENSP00000477611|ensembl:ENSP00000477750|ensembl:ENSP00000478935|ensembl:ENSP00000217893|uniprotkb:Q5U0D1|uniprotkb:Q9BTS1|uniprotkb:D3DWA3|intact:EBI-8645823|intact:MINT-8163548	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf9_human(display_long)|uniprotkb:Transcription initiation factor TFIID 31 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 32 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit G(gene name synonym)|uniprotkb:STAF31/32(gene name synonym)|uniprotkb:TAF9(gene name)|psi-mi:TAF9(display_short)|uniprotkb:TAF2G(gene name synonym)|uniprotkb:TAFII31(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	ensembl:ENST00000217893(transcript)|ensembl:ENST00000328663(transcript)|ensembl:ENST00000506736(transcript)|ensembl:ENST00000615404(transcript)|ensembl:ENST00000616867(transcript)|ensembl:ENST00000617893(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030914"|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:0071339"(MLL1 complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|mint:Q16594|rcsb pdb:6F3T|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-3214847|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|ensembl:ENSG00000273841(gene)|ensembl:ENSG00000276463(gene)|refseq:NP_001015892.1|refseq:NP_003178.1|dip:DIP-435N	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:Drikn9IwpWQXbTTXGqwf1hlRNE09606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
intact:EBI-1173115	uniprotkb:P21675	-	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560048|imex:IM-11882-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	comment:All these proteins bound most favourably to the trimethylated peptide|figure legend:Fig 1, 5, Sup Table 2|comment:H3K4me3 binding by TAF1 and TAF7 is compromised by the asymmetric dimethylation of Arg-2. Binding of the BPTF protein was not affected.|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	intact-crc:9E47F2EA95A7645E|rigid:JQoh/T+R9UJ3tt6wCRGt8yFQxp8	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)	psi-mi:"MI:0032"(de novo protein sequencing by mass spectrometry)
uniprotkb:P20226	ensembl:ENSG00000113161	intact:EBI-355371|uniprotkb:Q16845|uniprotkb:Q9UC02|intact:EBI-1056192|uniprotkb:Q6IBM6|ensembl:ENSP00000230354|ensembl:ENSP00000375942|intact:EBI-11019728|uniprotkb:B4E3B3|uniprotkb:F5H869	intact:EBI-1560912	psi-mi:tbp_human(display_long)|uniprotkb:TBP(gene name)|psi-mi:TBP(display_short)|uniprotkb:TF2D(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:GTF2D1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:hmdh_human_gene(display_short)|psi-mi:ENSG00000113161(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560969|imex:IM-11882-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001165556.1|refseq:NP_003185.1|ensembl:ENSP00000230354|ensembl:ENSP00000375942|ensembl:ENST00000540980|ensembl:ENSP00000442132|ensembl:ENSG00000112592(gene)|ensembl:ENST00000230354(transcript)|ensembl:ENST00000392092(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|mint:P20226|rcsb pdb:1C9B|rcsb pdb:1CDW|rcsb pdb:1JFI|rcsb pdb:1NVP|rcsb pdb:1TGH|rcsb pdb:4ROC|rcsb pdb:4ROD|rcsb pdb:4ROE|rcsb pdb:5FUR|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5N9G|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-427359|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-9018519|dip:DIP-1078N	-	-	-	-	figure legend:Figure 2C|comment:"Interaction requires presence of WDR5 protein (P61964)"|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2007/11/29	2014/10/16	rogid:tH4ckPOwO4Icr1YsnJ1Ck/6Cgmo9606	-	intact-crc:BAA1D67604F7C2C4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
ensembl:ENSG00000115414	uniprotkb:P20226	intact:EBI-1560930	intact:EBI-355371|uniprotkb:Q16845|uniprotkb:Q9UC02|intact:EBI-1056192|uniprotkb:Q6IBM6|ensembl:ENSP00000230354|ensembl:ENSP00000375942|intact:EBI-11019728|uniprotkb:B4E3B3|uniprotkb:F5H869	psi-mi:finc_human_gene(display_short)|psi-mi:ENSG00000115414(display_long)	psi-mi:tbp_human(display_long)|uniprotkb:TBP(gene name)|psi-mi:TBP(display_short)|uniprotkb:TF2D(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:GTF2D1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1560974|imex:IM-11882-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001165556.1|refseq:NP_003185.1|ensembl:ENSP00000230354|ensembl:ENSP00000375942|ensembl:ENST00000540980|ensembl:ENSP00000442132|ensembl:ENSG00000112592(gene)|ensembl:ENST00000230354(transcript)|ensembl:ENST00000392092(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|mint:P20226|rcsb pdb:1C9B|rcsb pdb:1CDW|rcsb pdb:1JFI|rcsb pdb:1NVP|rcsb pdb:1TGH|rcsb pdb:4ROC|rcsb pdb:4ROD|rcsb pdb:4ROE|rcsb pdb:5FUR|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5N9G|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-427359|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-9018519|dip:DIP-1078N	-	-	-	figure legend:Figure 2C|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2007/11/29	2014/10/16	-	rogid:tH4ckPOwO4Icr1YsnJ1Ck/6Cgmo9606	intact-crc:0B8ABB2E7BEA8A5F	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P20226	ensembl:ENSG00000109475	intact:EBI-355371|uniprotkb:Q16845|uniprotkb:Q9UC02|intact:EBI-1056192|uniprotkb:Q6IBM6|ensembl:ENSP00000230354|ensembl:ENSP00000375942|intact:EBI-11019728|uniprotkb:B4E3B3|uniprotkb:F5H869	intact:EBI-1560937	psi-mi:tbp_human(display_long)|uniprotkb:TBP(gene name)|psi-mi:TBP(display_short)|uniprotkb:TF2D(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:GTF2D1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:rl34_human_gene(display_short)|psi-mi:ENSG00000109475(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561004|imex:IM-11882-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001165556.1|refseq:NP_003185.1|ensembl:ENSP00000230354|ensembl:ENSP00000375942|ensembl:ENST00000540980|ensembl:ENSP00000442132|ensembl:ENSG00000112592(gene)|ensembl:ENST00000230354(transcript)|ensembl:ENST00000392092(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|mint:P20226|rcsb pdb:1C9B|rcsb pdb:1CDW|rcsb pdb:1JFI|rcsb pdb:1NVP|rcsb pdb:1TGH|rcsb pdb:4ROC|rcsb pdb:4ROD|rcsb pdb:4ROE|rcsb pdb:5FUR|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5N9G|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-427359|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-9018519|dip:DIP-1078N	-	-	-	-	figure legend:Figure 2D|comment:"Interaction requires presence of WDR5 protein (P61964)"|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2007/11/29	2014/10/16	rogid:tH4ckPOwO4Icr1YsnJ1Ck/6Cgmo9606	-	intact-crc:8E8E67AF4D15929C	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
ensembl:ENSG00000109475	uniprotkb:P21675	intact:EBI-1560937	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	psi-mi:rl34_human_gene(display_short)|psi-mi:ENSG00000109475(display_long)	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561021|imex:IM-11882-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N	-	-	-	figure legend:Figure 2D|comment:"Interaction requires presence of WDR5 protein (P61964)"|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2007/11/29	2014/10/16	-	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	intact-crc:92B1B4BB1433F574	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
ensembl:ENSG00000071082	uniprotkb:P21675	intact:EBI-1560948	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	psi-mi:rpl31_human_gene(display_short)|psi-mi:ENSG00000071082(display_long)	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561027|imex:IM-11882-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N	-	-	-	figure legend:Figure 2E|comment:"Interaction requires presence of WDR5 protein (P61964)"|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2007/11/29	2014/10/16	-	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	intact-crc:4EAC30FA34907DC2	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
ensembl:ENSG00000071082	uniprotkb:P20226	intact:EBI-1560948	intact:EBI-355371|uniprotkb:Q16845|uniprotkb:Q9UC02|intact:EBI-1056192|uniprotkb:Q6IBM6|ensembl:ENSP00000230354|ensembl:ENSP00000375942|intact:EBI-11019728|uniprotkb:B4E3B3|uniprotkb:F5H869	psi-mi:rpl31_human_gene(display_short)|psi-mi:ENSG00000071082(display_long)	psi-mi:tbp_human(display_long)|uniprotkb:TBP(gene name)|psi-mi:TBP(display_short)|uniprotkb:TF2D(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:GTF2D1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561033|imex:IM-11882-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001165556.1|refseq:NP_003185.1|ensembl:ENSP00000230354|ensembl:ENSP00000375942|ensembl:ENST00000540980|ensembl:ENSP00000442132|ensembl:ENSG00000112592(gene)|ensembl:ENST00000230354(transcript)|ensembl:ENST00000392092(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|mint:P20226|rcsb pdb:1C9B|rcsb pdb:1CDW|rcsb pdb:1JFI|rcsb pdb:1NVP|rcsb pdb:1TGH|rcsb pdb:4ROC|rcsb pdb:4ROD|rcsb pdb:4ROE|rcsb pdb:5FUR|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5N9G|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-427359|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-9018519|dip:DIP-1078N	-	-	-	figure legend:Figure 2E|comment:"Interaction requires presence of WDR5 protein (P61964)"|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2007/11/29	2014/10/16	-	rogid:tH4ckPOwO4Icr1YsnJ1Ck/6Cgmo9606	intact-crc:5293E3EE6DB61A2A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
ensembl:ENSG00000124614	uniprotkb:P20226	intact:EBI-1561047	intact:EBI-355371|uniprotkb:Q16845|uniprotkb:Q9UC02|intact:EBI-1056192|uniprotkb:Q6IBM6|ensembl:ENSP00000230354|ensembl:ENSP00000375942|intact:EBI-11019728|uniprotkb:B4E3B3|uniprotkb:F5H869	psi-mi:rps10_human_gene(display_short)|psi-mi:ENSG00000124614(display_long)	psi-mi:tbp_human(display_long)|uniprotkb:TBP(gene name)|psi-mi:TBP(display_short)|uniprotkb:TF2D(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:GTF2D1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561060|imex:IM-11882-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0250"(gene)	psi-mi:"MI:0326"(protein)	-	refseq:NP_001165556.1|refseq:NP_003185.1|ensembl:ENSP00000230354|ensembl:ENSP00000375942|ensembl:ENST00000540980|ensembl:ENSP00000442132|ensembl:ENSG00000112592(gene)|ensembl:ENST00000230354(transcript)|ensembl:ENST00000392092(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|mint:P20226|rcsb pdb:1C9B|rcsb pdb:1CDW|rcsb pdb:1JFI|rcsb pdb:1NVP|rcsb pdb:1TGH|rcsb pdb:4ROC|rcsb pdb:4ROD|rcsb pdb:4ROE|rcsb pdb:5FUR|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5N9G|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-427359|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-9018519|dip:DIP-1078N	-	-	-	figure legend:Figure S6|comment:"Interaction requires presence of WDR5 protein (P61964)"|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2007/11/29	2014/10/16	-	rogid:tH4ckPOwO4Icr1YsnJ1Ck/6Cgmo9606	intact-crc:1D098972FF05F3FE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P21675	ensembl:ENSG00000124614	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	intact:EBI-1561047	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:rps10_human_gene(display_short)|psi-mi:ENSG00000124614(display_long)	psi-mi:"MI:0413"(electrophoretic mobility shift assay)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561066|imex:IM-11882-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N	-	-	-	-	figure legend:Figure S6|comment:"Interaction requires presence of WDR5 protein (P61964)"|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-u2-os)|taxid:9606(Human U2-OS osteosarcoma cell line)	-	2007/11/29	2014/10/16	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	-	intact-crc:01365A66A6239416	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-1173115	uniprotkb:Q5HZG4	-	intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561079|imex:IM-11882-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042	psi-mi:"MI:0469"(intact)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	figure legend:Figure 3B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090	intact-crc:65B5AA77F0A9DDC9|rigid:6IOYvFdo7Il/7aqO7ys8aNKli24	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	necessary binding region:862-918(IPR001965)|ha tag:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-1173115	uniprotkb:Q15545	-	intact:EBI-1560194|uniprotkb:Q13036|uniprotkb:B2RBV9|ensembl:ENSP00000312709	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf7_human(display_long)|uniprotkb:Transcription initiation factor TFIID 55 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit F(gene name synonym)|uniprotkb:TAF7(gene name)|psi-mi:TAF7(display_short)|uniprotkb:TAF2F(gene name synonym)|uniprotkb:TAFII55(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561079|imex:IM-11882-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_005633.2|dip:DIP-29047N|ensembl:ENSG00000178913(gene)|ensembl:ENST00000313368(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000296"(spermine transport)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045344"(negative regulation of MHC class I biosynthetic process)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0106140"(P-TEFb complex binding)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|rcsb pdb:4RGW|rcsb pdb:5FUR|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	psi-mi:"MI:0469"(intact)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	figure legend:Figure 3B|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:FFk04k421YC/B0n/5GXpDK9uhBU9606	intact-crc:65B5AA77F0A9DDC9|rigid:6IOYvFdo7Il/7aqO7ys8aNKli24	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-1173115	uniprotkb:Q5HZG4	-	intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561323|imex:IM-11882-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042	go:"GO:0035064"(methylated histone binding)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	figure legend:Figure 3C and 3D|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090	intact-crc:9277867EA3829A62|rigid:jllf65NkBhq0ql4nXFMV/NuM3Yo	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	necessary binding region:857-924(IPR001965)|glutathione s tranferase tag:?-?|mutation decreasing interaction:882-882|mutation decreasing interaction:886-886|mutation decreasing interaction:890-891	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-1173115	uniprotkb:Q5HZG4	-	intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561372|imex:IM-11882-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042	psi-mi:"MI:0469"(intact)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	figure legend:Figure 3E, 5B|comment:"The TAF3 PHD domain has a much higher affinity for H3K4me3 compared to the ING2 PHD domain. ING2 and TAF3-PHD finger have a similar affinity for the doubly methylated peptide (R2me2a/K4me3)."|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090	intact-crc:6C1737159957050F|rigid:IEmGbdAcSW6ipFKEdaLUqYYBEbY	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c|asymmetric dimethyl-L-arginine:2-2	necessary binding region:857-924(IPR001965)|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-1173115	uniprotkb:Q9ESK4	-	intact:EBI-1561388|uniprotkb:Q80VI5|uniprotkb:Q8BGU8|uniprotkb:Q4VAD7|ensembl:ENSMUSP00000079226	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:ing2_mouse(display_long)|uniprotkb:p33ING2(gene name synonym)|uniprotkb:Inhibitor of growth 1-like protein(gene name synonym)|uniprotkb:Ing2(gene name)|psi-mi:Ing2(display_short)|uniprotkb:Ing1l(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561372|imex:IM-11882-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_075992.2|dip:DIP-38912N|ensembl:ENSMUSG00000063049(gene)|ensembl:ENSMUST00000080353(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028639|interpro:IPR028651|interpro:IPR042019|rcsb pdb:1WES|rcsb pdb:2G6Q|reactome:R-MMU-3899300|reactome:R-MMU-6811555	psi-mi:"MI:0469"(intact)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	figure legend:Figure 3E, 5B|comment:"The TAF3 PHD domain has a much higher affinity for H3K4me3 compared to the ING2 PHD domain. ING2 and TAF3-PHD finger have a similar affinity for the doubly methylated peptide (R2me2a/K4me3)."|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:9pxLKzNNiUMtG+a2Z4SLTaiaUNQ10090	intact-crc:6C1737159957050F|rigid:IEmGbdAcSW6ipFKEdaLUqYYBEbY	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c|asymmetric dimethyl-L-arginine:2-2	sufficient binding region:213..213-262..262(IPR001965)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9ESK4	intact:EBI-1173115	intact:EBI-1561388|uniprotkb:Q80VI5|uniprotkb:Q8BGU8|uniprotkb:Q4VAD7|ensembl:ENSMUSP00000079226	-	psi-mi:ing2_mouse(display_long)|uniprotkb:p33ING2(gene name synonym)|uniprotkb:Inhibitor of growth 1-like protein(gene name synonym)|uniprotkb:Ing2(gene name)|psi-mi:Ing2(display_short)|uniprotkb:Ing1l(gene name synonym)	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:-1(in vitro)|taxid:-1(In vitro)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561420|imex:IM-11882-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	refseq:NP_075992.2|dip:DIP-38912N|ensembl:ENSMUSG00000063049(gene)|ensembl:ENSMUST00000080353(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028639|interpro:IPR028651|interpro:IPR042019|rcsb pdb:1WES|rcsb pdb:2G6Q|reactome:R-MMU-3899300|reactome:R-MMU-6811555	-	psi-mi:"MI:0469"(intact)	-	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	figure legend:Figure 3E|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/29	2014/10/16	rogid:9pxLKzNNiUMtG+a2Z4SLTaiaUNQ10090	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	intact-crc:45511B8DA7B60356|rigid:C9uHEHuCIYfWlhGf0KTuzJ8lEV0	false	sufficient binding region:213..213-262..262(IPR001965)	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9ESK4	intact:EBI-1173115	intact:EBI-1561388|uniprotkb:Q80VI5|uniprotkb:Q8BGU8|uniprotkb:Q4VAD7|ensembl:ENSMUSP00000079226	-	psi-mi:ing2_mouse(display_long)|uniprotkb:p33ING2(gene name synonym)|uniprotkb:Inhibitor of growth 1-like protein(gene name synonym)|uniprotkb:Ing2(gene name)|psi-mi:Ing2(display_short)|uniprotkb:Ing1l(gene name synonym)	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:-1(in vitro)|taxid:-1(In vitro)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561439|imex:IM-11882-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	refseq:NP_075992.2|dip:DIP-38912N|ensembl:ENSMUSG00000063049(gene)|ensembl:ENSMUST00000080353(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028639|interpro:IPR028651|interpro:IPR042019|rcsb pdb:1WES|rcsb pdb:2G6Q|reactome:R-MMU-3899300|reactome:R-MMU-6811555	-	psi-mi:"MI:0469"(intact)	-	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	figure legend:Figure 3E|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/29	2014/10/16	rogid:9pxLKzNNiUMtG+a2Z4SLTaiaUNQ10090	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	intact-crc:3AE50AE0D6CAD3AB|rigid:C9uHEHuCIYfWlhGf0KTuzJ8lEV0	false	sufficient binding region:213..213-262..262(IPR001965)	N6,N6-dimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-1173115	uniprotkb:Q9ESK4	-	intact:EBI-1561388|uniprotkb:Q80VI5|uniprotkb:Q8BGU8|uniprotkb:Q4VAD7|ensembl:ENSMUSP00000079226	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:ing2_mouse(display_long)|uniprotkb:p33ING2(gene name synonym)|uniprotkb:Inhibitor of growth 1-like protein(gene name synonym)|uniprotkb:Ing2(gene name)|psi-mi:Ing2(display_short)|uniprotkb:Ing1l(gene name synonym)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561453|imex:IM-11882-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0586"(inhibitor)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	refseq:NP_075992.2|dip:DIP-38912N|ensembl:ENSMUSG00000063049(gene)|ensembl:ENSMUST00000080353(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016602"(CCAAT-binding factor complex)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028639|interpro:IPR028651|interpro:IPR042019|rcsb pdb:1WES|rcsb pdb:2G6Q|reactome:R-MMU-3899300|reactome:R-MMU-6811555	psi-mi:"MI:0469"(intact)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	figure legend:Figure 3E|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:9pxLKzNNiUMtG+a2Z4SLTaiaUNQ10090	intact-crc:1D1EFD21B6B834F2|rigid:IEmGbdAcSW6ipFKEdaLUqYYBEbY	false	N6,N6-dimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	sufficient binding region:213..213-262..262(IPR001965)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
intact:EBI-1173115	uniprotkb:Q5HZG4	-	intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561453|imex:IM-11882-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042	psi-mi:"MI:0469"(intact)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	figure legend:Figure 3E|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090	intact-crc:1D1EFD21B6B834F2|rigid:IEmGbdAcSW6ipFKEdaLUqYYBEbY	false	N6,N6-dimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	necessary binding region:857-924(IPR001965)|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5HZG4	intact:EBI-1173115	intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888	-	psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:-1(in vitro)|taxid:-1(In vitro)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561592|imex:IM-11882-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042	-	psi-mi:"MI:0469"(intact)	-	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	figure legend:Figure 3C, 5A|comment:Asymmetric dimethylation of H3R2 drastically reduces the binding of the TAF3 PHD domain to H3K4me3,|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/29	2014/10/16	rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	intact-crc:D87E52DEA0B0A47D|rigid:jllf65NkBhq0ql4nXFMV/NuM3Yo	false	mutation decreasing interaction:882-882|mutation decreasing interaction:886-886|mutation decreasing interaction:890-891|necessary binding region:857-924(IPR001965)|glutathione s tranferase tag:?-?	N6,N6-dimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c|asymmetric dimethyl-L-arginine:2-2	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5HZG4	uniprotkb:P61830	intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888	intact:EBI-8098|uniprotkb:E9PAG1|uniprotkb:P02303|uniprotkb:P13996|uniprotkb:Q6B1U3|uniprotkb:Q6Q7G9|uniprotkb:D6VQ11|ensemblfungi:YBR010W|ensemblfungi:YNL031C	psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)	psi-mi:h3_yeast(display_long)|uniprotkb:SIN2(gene name synonym)|uniprotkb:YNL031C(locus name)|uniprotkb:N2749(orf name)|uniprotkb:HHT1(gene name)|psi-mi:HHT1(display_short)|uniprotkb:YBR010W(locus name)|uniprotkb:YBR0201(orf name)|uniprotkb:HHT2(gene name)|psi-mi:HHT2(display_short)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561621|imex:IM-11882-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042	refseq:NP_009564.1|refseq:NP_014367.1|sgd:S000000214|sgd:S000004976|mint:P61830|dip:DIP-417N|ensemblfungi:YBR010W(gene)|ensemblfungi:YBR010W_mRNA(transcript)|ensemblfungi:YNL031C(gene)|ensemblfungi:YNL031C_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0009303"(rRNA transcription)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0043505"(CENP-A containing nucleosome)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070911"(global genome nucleotide-excision repair)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|rcsb pdb:1ID3|rcsb pdb:1M1D|rcsb pdb:1PEG|rcsb pdb:1PU9|rcsb pdb:1PUA|rcsb pdb:1QSN|rcsb pdb:2CNX|rcsb pdb:2H2G|rcsb pdb:2IDC|rcsb pdb:2JMJ|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:2RSN|rcsb pdb:3MP1|rcsb pdb:3MP6|rcsb pdb:3Q33|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:5D7E|rcsb pdb:5IOK|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6J2P|rcsb pdb:6KMJ|rcsb pdb:7K7G	psi-mi:"MI:0469"(intact)	-	crc64:A6115FEB480AC67A	figure legend:Figure 4C, 4E|comment:Deletion of enzymes responsible for methylating H3 at lys-5 result in a loss of the interaction|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/29	2014/10/16	rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090	rogid:jtDVNjrs2tJMmr/dqrvnNiQ2ppQ559292	intact-crc:543A7DCBAFE7125B|rigid:hJeuKatlrv/fyIgiAAPxYZA/TM0	false	mutation decreasing interaction:882-882|mutation decreasing interaction:886-886|mutation decreasing interaction:890-891|necessary binding region:857-924(IPR001965)|glutathione s tranferase tag:?-?	N6,N6,N6-trimethyl-L-lysine:5-5	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5HZG4	uniprotkb:P02309	intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888	intact:EBI-8113|uniprotkb:D6VQ10|ensemblfungi:YBR009C|ensemblfungi:YNL030W	psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)	psi-mi:h4_yeast(display_long)|uniprotkb:N2752(orf name)|uniprotkb:YBR0122(orf name)|uniprotkb:YBR009C(locus name)|uniprotkb:YNL030W(locus name)|uniprotkb:HHF1(gene name)|psi-mi:HHF1(display_short)|uniprotkb:HHF2(gene name)|psi-mi:HHF2(display_short)	psi-mi:"MI:0096"(pull down)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561621|imex:IM-11882-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042	refseq:NP_009563.1|refseq:NP_014368.1|sgd:S000000213|sgd:S000004975|dip:DIP-418N|mint:P02309|ensemblfungi:YBR009C(gene)|ensemblfungi:YBR009C_mRNA(transcript)|ensemblfungi:YNL030W(gene)|ensemblfungi:YNL030W_mRNA(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031298"(replication fork protection complex)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0043935"(sexual sporulation resulting in formation of a cellular spore)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061587"(transfer RNA gene-mediated silencing)|interpro:IPR001951(Histone H4)|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|rcsb pdb:1E6I|rcsb pdb:1ID3|rcsb pdb:1Q1A|rcsb pdb:1SZC|rcsb pdb:1SZD|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2E3K|rcsb pdb:2FSB|rcsb pdb:2H2H|rcsb pdb:2L5A|rcsb pdb:2QQF|rcsb pdb:2QQG|rcsb pdb:3TO6|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4PSX|rcsb pdb:4TWI|rcsb pdb:4TWJ|rcsb pdb:5W0V|rcsb pdb:5ZBA|rcsb pdb:5ZBB|rcsb pdb:6GEJ|rcsb pdb:6GEN|rcsb pdb:6QLD|rcsb pdb:6RXJ|rcsb pdb:6RXK|rcsb pdb:6RXL|rcsb pdb:6RXM|rcsb pdb:6RXO|rcsb pdb:6RXP|rcsb pdb:6RXQ|rcsb pdb:6RXR|rcsb pdb:7K78|rcsb pdb:7K7G|reactome:R-SCE-2299718|reactome:R-SCE-2559580|reactome:R-SCE-3214842|reactome:R-SCE-3214847|reactome:R-SCE-3214858|reactome:R-SCE-4551638|reactome:R-SCE-9018519	psi-mi:"MI:0469"(intact)	-	crc64:69B7D1F89E62DE41	figure legend:Figure 4C, 4E|comment:Deletion of enzymes responsible for methylating H3 at lys-5 result in a loss of the interaction|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/29	2014/10/16	rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090	rogid:wGtUrumyxGKsW9BEzkBW3FwvwUo559292	intact-crc:543A7DCBAFE7125B|rigid:hJeuKatlrv/fyIgiAAPxYZA/TM0	false	mutation decreasing interaction:882-882|mutation decreasing interaction:886-886|mutation decreasing interaction:890-891|necessary binding region:857-924(IPR001965)|glutathione s tranferase tag:?-?	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q5HZG4	intact:EBI-1173115	intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888	-	psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:-1(in vitro)|taxid:-1(In vitro)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561481|imex:IM-11882-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0327"(peptide)	ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042	-	psi-mi:"MI:0469"(intact)	-	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	figure legend:Figure 3F|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/29	2014/10/16	rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	intact-crc:9F6632FA6285DE8E|rigid:jllf65NkBhq0ql4nXFMV/NuM3Yo	false	necessary binding region:857-924(IPR001965)|glutathione s tranferase tag:?-?	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-1173115	uniprotkb:Q5HZG4	-	intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561497|imex:IM-11882-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042	psi-mi:"MI:0469"(intact)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	figure legend:Figure 3F|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090	intact-crc:1412EC5198011075|rigid:jllf65NkBhq0ql4nXFMV/NuM3Yo	false	N6,N6-dimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c	necessary binding region:857-924(IPR001965)|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-1173115	uniprotkb:Q5HZG4	-	intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561513|imex:IM-11882-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042	psi-mi:"MI:0469"(intact)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	figure legend:Figure 3F|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090	intact-crc:1AFC6A72C9744407|rigid:jllf65NkBhq0ql4nXFMV/NuM3Yo	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c|omega-N-methyl-L-arginine:2-2	necessary binding region:857-924(IPR001965)|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-1173115	uniprotkb:Q5HZG4	-	intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561531|imex:IM-11882-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042	psi-mi:"MI:0469"(intact)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	figure legend:Figure 3F|comment:Kd=4.2E-6M for the asymmetric substitution,  3.0E-7M for the symmetric|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090	intact-crc:E776AF24304D1D56|rigid:jllf65NkBhq0ql4nXFMV/NuM3Yo	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c|asymmetric dimethyl-L-arginine:2-2	necessary binding region:857-924(IPR001965)|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
intact:EBI-1173115	uniprotkb:Q5HZG4	-	intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888	psi-mi:h3_peptide_2-18(display_short)|psi-mi:EBI-1173115(display_long)	psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)	psi-mi:"MI:0017"(classical fluorescence spectroscopy)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:-1(in vitro)|taxid:-1(In vitro)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561550|imex:IM-11882-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0327"(peptide)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042	psi-mi:"MI:0469"(intact)	no-uniprot-update:An amino acid sequence which is not represented in UniProt|comment:Conserved n-terminal sequence in mouse, human, arath, encal, chick, brana, eupes, crilo, calmo, cicin, rat, bovin, ictu, schpo, xentr and more corresponds to AA 1-18 of histone H3.|no-uniprot-update:	-	figure legend:Figure 3F|comment:Kd=4.2E-6M for the asymmetric substitution,  3.0E-7M for the symmetric|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/29	2014/10/16	rogid:5/B2Q2AosP2VbBsA3uM0whjxnbM-1	rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090	intact-crc:B78C64FAC52E46CC|rigid:jllf65NkBhq0ql4nXFMV/NuM3Yo	false	N6,N6,N6-trimethyl-L-lysine:4-4|mutation:17-17|biotin tag:c-c|N-acetylated L-lysine:9-9|N-acetylated L-lysine:14-14	necessary binding region:857-924(IPR001965)|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q5HZG4	uniprotkb:Q15542	intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888	intact:EBI-1560145|uniprotkb:Q53EM4|uniprotkb:Q5SYD5|uniprotkb:Q86UZ7|uniprotkb:Q9Y4K5|uniprotkb:A8K5B4|uniprotkb:B2RMR0|uniprotkb:B7ZKJ6|ensembl:ENSP00000358854	psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)	psi-mi:taf5_human(display_long)|uniprotkb:Transcription initiation factor TFIID 100 kDa subunit(gene name synonym)|uniprotkb:TAF5(gene name)|psi-mi:TAF5(display_short)|uniprotkb:TAF2D(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561735|imex:IM-11882-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042	refseq:NP_008882.2|refseq:NP_620640.1|dip:DIP-28150N|ensembl:ENSG00000148835(gene)|ensembl:ENST00000369839(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007582(WD40 associated region in TFIID subunit)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037264|interpro:IPR037783|rcsb pdb:2NXP|rcsb pdb:6F3T|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	psi-mi:"MI:0469"(intact)	-	-	figure legend:Supp. Fig. S7|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090	rogid:PKpggshlmaWo83aeQNxZ4PDb1Eo9606	intact-crc:C9C7773DF207D2FA|rigid:55tyhvohKh0wFJvernmz2TIYj2I	false	sufficient binding region:1-850|flag tag:c-c|ha tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5HZG4	uniprotkb:P20226	intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888	intact:EBI-355371|uniprotkb:Q16845|uniprotkb:Q9UC02|intact:EBI-1056192|uniprotkb:Q6IBM6|ensembl:ENSP00000230354|ensembl:ENSP00000375942|intact:EBI-11019728|uniprotkb:B4E3B3|uniprotkb:F5H869	psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)	psi-mi:tbp_human(display_long)|uniprotkb:TBP(gene name)|psi-mi:TBP(display_short)|uniprotkb:TF2D(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:GTF2D1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561735|imex:IM-11882-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042	refseq:NP_001165556.1|refseq:NP_003185.1|ensembl:ENSP00000230354|ensembl:ENSP00000375942|ensembl:ENST00000540980|ensembl:ENSP00000442132|ensembl:ENSG00000112592(gene)|ensembl:ENST00000230354(transcript)|ensembl:ENST00000392092(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|mint:P20226|rcsb pdb:1C9B|rcsb pdb:1CDW|rcsb pdb:1JFI|rcsb pdb:1NVP|rcsb pdb:1TGH|rcsb pdb:4ROC|rcsb pdb:4ROD|rcsb pdb:4ROE|rcsb pdb:5FUR|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5N9G|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-427359|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-9018519|dip:DIP-1078N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Supp. Fig. S7|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090	rogid:tH4ckPOwO4Icr1YsnJ1Ck/6Cgmo9606	intact-crc:C9C7773DF207D2FA|rigid:55tyhvohKh0wFJvernmz2TIYj2I	false	sufficient binding region:1-850|flag tag:c-c|ha tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5HZG4	uniprotkb:P21675	intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1561735|imex:IM-11882-16	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Supp. Fig. S7|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	intact-crc:C9C7773DF207D2FA|rigid:55tyhvohKh0wFJvernmz2TIYj2I	false	sufficient binding region:1-850|flag tag:c-c|ha tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P20226	uniprotkb:Q5HZG4	intact:EBI-355371|uniprotkb:Q16845|uniprotkb:Q9UC02|intact:EBI-1056192|uniprotkb:Q6IBM6|ensembl:ENSP00000230354|ensembl:ENSP00000375942|intact:EBI-11019728|uniprotkb:B4E3B3|uniprotkb:F5H869	intact:EBI-1561080|uniprotkb:Q3U490|uniprotkb:Q3UWX2|uniprotkb:Q8BIU8|uniprotkb:Q99JH4|ensembl:ENSMUSP00000026888	psi-mi:tbp_human(display_long)|uniprotkb:TBP(gene name)|psi-mi:TBP(display_short)|uniprotkb:TF2D(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:GTF2D1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:taf3_mouse(display_long)|uniprotkb:TBP-associated factor 3(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 140 kDa subunit(gene name synonym)|uniprotkb:140 kDa TATA box-binding protein-associated factor(gene name synonym)|uniprotkb:Taf3(gene name)|psi-mi:Taf3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1565027|imex:IM-11882-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001165556.1|refseq:NP_003185.1|ensembl:ENSP00000230354|ensembl:ENSP00000375942|ensembl:ENST00000540980|ensembl:ENSP00000442132|ensembl:ENSG00000112592(gene)|ensembl:ENST00000230354(transcript)|ensembl:ENST00000392092(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|mint:P20226|rcsb pdb:1C9B|rcsb pdb:1CDW|rcsb pdb:1JFI|rcsb pdb:1NVP|rcsb pdb:1TGH|rcsb pdb:4ROC|rcsb pdb:4ROD|rcsb pdb:4ROE|rcsb pdb:5FUR|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5N9G|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-427359|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-9018519|dip:DIP-1078N	ensembl:ENSMUSG00000025782(gene)|ensembl:ENSMUST00000026888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR001965(Zinc finger, PHD-type)|refseq:NP_082024.2|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q5HZG4|rcsb pdb:2K16|rcsb pdb:2K17|reactome:R-MMU-674695|reactome:R-MMU-6804756|reactome:R-MMU-73776|reactome:R-MMU-73779|reactome:R-MMU-75953|reactome:R-MMU-76042	psi-mi:"MI:0469"(intact)	-	-	figure legend:Supp. Fig. S7|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:tH4ckPOwO4Icr1YsnJ1Ck/6Cgmo9606	rogid:DbdYFYkZWMcfYWOQmL+j88K3s2o10090	intact-crc:2B53B6DAA0F613AD|rigid:55tyhvohKh0wFJvernmz2TIYj2I	false	-	flag tag:c-c|ha tag:c-c|sufficient binding region:1-850	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P20226	uniprotkb:P21675	intact:EBI-355371|uniprotkb:Q16845|uniprotkb:Q9UC02|intact:EBI-1056192|uniprotkb:Q6IBM6|ensembl:ENSP00000230354|ensembl:ENSP00000375942|intact:EBI-11019728|uniprotkb:B4E3B3|uniprotkb:F5H869	intact:EBI-491289|uniprotkb:A5CVD0|uniprotkb:Q6IUZ1|uniprotkb:Q70Q86|uniprotkb:Q70Q87|uniprotkb:Q70T00|uniprotkb:Q70T01|uniprotkb:Q70T02|uniprotkb:Q70T03|uniprotkb:Q59FZ3|ensembl:ENSP00000276072|ensembl:ENSP00000362895|ensembl:ENSP00000406549|uniprotkb:A5CVC8|uniprotkb:A5CVC9|uniprotkb:A5CVD1|uniprotkb:B1Q2X3	psi-mi:tbp_human(display_long)|uniprotkb:TBP(gene name)|psi-mi:TBP(display_short)|uniprotkb:TF2D(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:GTF2D1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:taf1_human(display_long)|uniprotkb:TAF1(gene name)|psi-mi:TAF1(display_short)|uniprotkb:BA2R(gene name synonym)|uniprotkb:CCG1(gene name synonym)|uniprotkb:TAF2A(gene name synonym)|uniprotkb:CCGS(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 250 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 250 kDa(gene name synonym)|uniprotkb:Cell cycle gene 1 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1565027|imex:IM-11882-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001165556.1|refseq:NP_003185.1|ensembl:ENSP00000230354|ensembl:ENSP00000375942|ensembl:ENST00000540980|ensembl:ENSP00000442132|ensembl:ENSG00000112592(gene)|ensembl:ENST00000230354(transcript)|ensembl:ENST00000392092(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|mint:P20226|rcsb pdb:1C9B|rcsb pdb:1CDW|rcsb pdb:1JFI|rcsb pdb:1NVP|rcsb pdb:1TGH|rcsb pdb:4ROC|rcsb pdb:4ROD|rcsb pdb:4ROE|rcsb pdb:5FUR|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5N9G|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-427359|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-9018519|dip:DIP-1078N	refseq:NP_001273003.1|rcsb pdb:6MZM|refseq:NP_004597.2|refseq:NP_620278.1|rcsb pdb:6P38|rcsb pdb:6P39|rcsb pdb:6P3A|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7JJH|rcsb pdb:7L6X|rcsb pdb:7N42|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-167172|ensembl:ENSG00000147133(gene)|ensembl:ENST00000276072(transcript)|ensembl:ENST00000373790(transcript)|ensembl:ENST00000423759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001181"(RNA polymerase I general transcription initiation factor activity)|go:"GO:0002039"(p53 binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006361"(transcription initiation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030901"(midbrain development)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0016301"(kinase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071339"(MLL1 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903026"(negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1905524"(negative regulation of protein autoubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|interpro:IPR001487(Bromodomain)|interpro:IPR009067(TAFII-230 TBP-binding)|interpro:IPR011177(Transcription initiation factor TFIID subunit 1, animal)|interpro:IPR018359|interpro:IPR022591|interpro:IPR036427|interpro:IPR036741|interpro:IPR040240|interpro:IPR041670|mint:P21675|rcsb pdb:1EQF|rcsb pdb:3AAD|rcsb pdb:3UV4|rcsb pdb:3UV5|rcsb pdb:4RGW|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:5FUR|rcsb pdb:5I1Q|rcsb pdb:5I29|rcsb pdb:5MG2|rcsb pdb:6BQD|rcsb pdb:6FIC|rcsb pdb:6MZD|rcsb pdb:6MZL|refseq:XP_005262354.1|dip:DIP-147N	psi-mi:"MI:0469"(intact)	-	-	figure legend:Supp. Fig. S7|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:tH4ckPOwO4Icr1YsnJ1Ck/6Cgmo9606	rogid:P0LoULOvon+Wp2G17lBlqn3Fo4E9606	intact-crc:2B53B6DAA0F613AD|rigid:55tyhvohKh0wFJvernmz2TIYj2I	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P20226	uniprotkb:Q15542	intact:EBI-355371|uniprotkb:Q16845|uniprotkb:Q9UC02|intact:EBI-1056192|uniprotkb:Q6IBM6|ensembl:ENSP00000230354|ensembl:ENSP00000375942|intact:EBI-11019728|uniprotkb:B4E3B3|uniprotkb:F5H869	intact:EBI-1560145|uniprotkb:Q53EM4|uniprotkb:Q5SYD5|uniprotkb:Q86UZ7|uniprotkb:Q9Y4K5|uniprotkb:A8K5B4|uniprotkb:B2RMR0|uniprotkb:B7ZKJ6|ensembl:ENSP00000358854	psi-mi:tbp_human(display_long)|uniprotkb:TBP(gene name)|psi-mi:TBP(display_short)|uniprotkb:TF2D(gene name synonym)|uniprotkb:TFIID(gene name synonym)|uniprotkb:GTF2D1(gene name synonym)|uniprotkb:TATA-box factor(gene name synonym)|uniprotkb:TATA-binding factor(gene name synonym)|uniprotkb:TATA sequence-binding protein(gene name synonym)|uniprotkb:Transcription initiation factor TFIID TBP subunit(gene name synonym)	psi-mi:taf5_human(display_long)|uniprotkb:Transcription initiation factor TFIID 100 kDa subunit(gene name synonym)|uniprotkb:TAF5(gene name)|psi-mi:TAF5(display_short)|uniprotkb:TAF2D(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Vermeulen et al. (2007)	imex:IM-11882|pubmed:17884155	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1565027|imex:IM-11882-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001165556.1|refseq:NP_003185.1|ensembl:ENSP00000230354|ensembl:ENSP00000375942|ensembl:ENST00000540980|ensembl:ENSP00000442132|ensembl:ENSG00000112592(gene)|ensembl:ENST00000230354(transcript)|ensembl:ENST00000392092(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000995"(RNA polymerase III general transcription initiation factor activity)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001091"(RNA polymerase II general transcription initiation factor binding)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005672"(transcription factor TFIIA complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140223"(general transcription initiation factor activity)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000814(TATA-box binding)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR030491|interpro:IPR033710|mint:P20226|rcsb pdb:1C9B|rcsb pdb:1CDW|rcsb pdb:1JFI|rcsb pdb:1NVP|rcsb pdb:1TGH|rcsb pdb:4ROC|rcsb pdb:4ROD|rcsb pdb:4ROE|rcsb pdb:5FUR|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5N9G|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-427359|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-9018519|dip:DIP-1078N	refseq:NP_008882.2|refseq:NP_620640.1|dip:DIP-28150N|ensembl:ENSG00000148835(gene)|ensembl:ENST00000369839(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007582(WD40 associated region in TFIID subunit)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037264|interpro:IPR037783|rcsb pdb:2NXP|rcsb pdb:6F3T|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042	psi-mi:"MI:0469"(intact)	-	-	figure legend:Supp. Fig. S7|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/11/29	2014/10/16	rogid:tH4ckPOwO4Icr1YsnJ1Ck/6Cgmo9606	rogid:PKpggshlmaWo83aeQNxZ4PDb1Eo9606	intact-crc:2B53B6DAA0F613AD|rigid:55tyhvohKh0wFJvernmz2TIYj2I	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)