#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P50874	uniprotkb:P54791	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	intact:EBI-12580|uniprotkb:D6W4G3|ensemblfungi:YPR162C	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:orc4_yeast(display_long)|uniprotkb:ORC4(gene name)|psi-mi:ORC4(display_short)|uniprotkb:YPR162C(locus name)|uniprotkb:P9325.5(orf name)|uniprotkb:Origin recognition complex 56 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1532887|imex:IM-19741-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	ensemblfungi:YPR162C(gene)|ensemblfungi:YPR162C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68962|reactome:R-SCE-68949|refseq:NP_015488.1|sgd:S000006366|dip:DIP-2287N|mint:P54791	-	crc64:1FE5DE28AFF6B41C	crc64:ACF064F2C633F13F	figure legend:1 A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	rogid:kJZ5UJVsvZNFQEkBR9tmPOJ+Iv8559292	intact-crc:CDA9189E0B88D2C1|rigid:VcgGZc20PLK5diO6+LXtaRXojZw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54791	uniprotkb:P50874	intact:EBI-12580|uniprotkb:D6W4G3|ensemblfungi:YPR162C	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	psi-mi:orc4_yeast(display_long)|uniprotkb:ORC4(gene name)|psi-mi:ORC4(display_short)|uniprotkb:YPR162C(locus name)|uniprotkb:P9325.5(orf name)|uniprotkb:Origin recognition complex 56 kDa subunit(gene name synonym)	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1532894|imex:IM-19741-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR162C(gene)|ensemblfungi:YPR162C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68962|reactome:R-SCE-68949|refseq:NP_015488.1|sgd:S000006366|dip:DIP-2287N|mint:P54791	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	-	crc64:ACF064F2C633F13F	crc64:1FE5DE28AFF6B41C	figure legend:1 A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:kJZ5UJVsvZNFQEkBR9tmPOJ+Iv8559292	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	intact-crc:7E3DB27F01BD534B|rigid:VcgGZc20PLK5diO6+LXtaRXojZw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50874	uniprotkb:P32833	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	intact:EBI-12572|uniprotkb:D6VQ60|ensemblfungi:YBR060C	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:orc2_yeast(display_long)|uniprotkb:ORC2(gene name)|psi-mi:ORC2(display_short)|uniprotkb:RRR1(gene name synonym)|uniprotkb:SIR5(gene name synonym)|uniprotkb:YBR060C(locus name)|uniprotkb:YBR0523(orf name)|uniprotkb:Origin recognition complex 71 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1532907|imex:IM-19741-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0005664"(nuclear origin of replication recognition complex)|ensemblfungi:YBR060C(gene)|ensemblfungi:YBR060C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|refseq:NP_009616.1|sgd:S000000264|dip:DIP-2285N|mint:P32833	-	crc64:1FE5DE28AFF6B41C	crc64:486E3E5CE353807F	figure legend:1 A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	rogid:DO4QfmfwiE4RgbqHp4NRl5ryJhY559292	intact-crc:80F0DC4DD291160F|rigid:XBG9nkuF3uND+L7f5BhKl55gtBU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32833	uniprotkb:P50874	intact:EBI-12572|uniprotkb:D6VQ60|ensemblfungi:YBR060C	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	psi-mi:orc2_yeast(display_long)|uniprotkb:ORC2(gene name)|psi-mi:ORC2(display_short)|uniprotkb:RRR1(gene name synonym)|uniprotkb:SIR5(gene name synonym)|uniprotkb:YBR060C(locus name)|uniprotkb:YBR0523(orf name)|uniprotkb:Origin recognition complex 71 kDa subunit(gene name synonym)	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1532912|imex:IM-19741-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0005664"(nuclear origin of replication recognition complex)|ensemblfungi:YBR060C(gene)|ensemblfungi:YBR060C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|refseq:NP_009616.1|sgd:S000000264|dip:DIP-2285N|mint:P32833	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	-	crc64:486E3E5CE353807F	crc64:1FE5DE28AFF6B41C	figure legend:1 A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:DO4QfmfwiE4RgbqHp4NRl5ryJhY559292	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	intact-crc:63B37C000B9ADCAA|rigid:XBG9nkuF3uND+L7f5BhKl55gtBU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38826	uniprotkb:P32833	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	intact:EBI-12572|uniprotkb:D6VQ60|ensemblfungi:YBR060C	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:orc2_yeast(display_long)|uniprotkb:ORC2(gene name)|psi-mi:ORC2(display_short)|uniprotkb:RRR1(gene name synonym)|uniprotkb:SIR5(gene name synonym)|uniprotkb:YBR060C(locus name)|uniprotkb:YBR0523(orf name)|uniprotkb:Origin recognition complex 71 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1532969|imex:IM-19741-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0005664"(nuclear origin of replication recognition complex)|ensemblfungi:YBR060C(gene)|ensemblfungi:YBR060C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|refseq:NP_009616.1|sgd:S000000264|dip:DIP-2285N|mint:P32833	-	crc64:22803C70378B7E85	crc64:486E3E5CE353807F	figure legend:1 A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	rogid:DO4QfmfwiE4RgbqHp4NRl5ryJhY559292	intact-crc:5E247C1B6512238B|rigid:ZYTG5zpeAGvgWx3MHm3ih4HMRK4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32833	uniprotkb:P38826	intact:EBI-12572|uniprotkb:D6VQ60|ensemblfungi:YBR060C	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	psi-mi:orc2_yeast(display_long)|uniprotkb:ORC2(gene name)|psi-mi:ORC2(display_short)|uniprotkb:RRR1(gene name synonym)|uniprotkb:SIR5(gene name synonym)|uniprotkb:YBR060C(locus name)|uniprotkb:YBR0523(orf name)|uniprotkb:Origin recognition complex 71 kDa subunit(gene name synonym)	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1532974|imex:IM-19741-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0005664"(nuclear origin of replication recognition complex)|ensemblfungi:YBR060C(gene)|ensemblfungi:YBR060C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|refseq:NP_009616.1|sgd:S000000264|dip:DIP-2285N|mint:P32833	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	-	crc64:486E3E5CE353807F	crc64:22803C70378B7E85	figure legend:1 A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:DO4QfmfwiE4RgbqHp4NRl5ryJhY559292	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	intact-crc:FCC28B235DFDF342|rigid:ZYTG5zpeAGvgWx3MHm3ih4HMRK4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32833	uniprotkb:P54790	intact:EBI-12572|uniprotkb:D6VQ60|ensemblfungi:YBR060C	intact:EBI-12576|uniprotkb:D6VXZ9|ensemblfungi:YLL004W	psi-mi:orc2_yeast(display_long)|uniprotkb:ORC2(gene name)|psi-mi:ORC2(display_short)|uniprotkb:RRR1(gene name synonym)|uniprotkb:SIR5(gene name synonym)|uniprotkb:YBR060C(locus name)|uniprotkb:YBR0523(orf name)|uniprotkb:Origin recognition complex 71 kDa subunit(gene name synonym)	psi-mi:orc3_yeast(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:OAF1(gene name synonym)|uniprotkb:OIF1(gene name synonym)|uniprotkb:YLL004W(locus name)|uniprotkb:L1365(orf name)|uniprotkb:Origin recognition complex 62 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1532979|imex:IM-19741-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0005664"(nuclear origin of replication recognition complex)|ensemblfungi:YBR060C(gene)|ensemblfungi:YBR060C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|refseq:NP_009616.1|sgd:S000000264|dip:DIP-2285N|mint:P32833	ensemblfungi:YLL004W(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR018247|interpro:IPR020795|interpro:IPR040855|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|ensemblfungi:YLL004W_mRNA(transcript)|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|rcsb pdb:7MCA|refseq:NP_013097.1|sgd:S000003927|dip:DIP-2286N|mint:P54790	-	crc64:486E3E5CE353807F	crc64:3FAAEE3F645D3F9C	figure legend:1 A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:DO4QfmfwiE4RgbqHp4NRl5ryJhY559292	rogid:OHTvxxS+UI2qEDyZ+wyi2v0nhlI559292	intact-crc:51CA29A0033D05E5|rigid:DyDVTuLRgPBwiZUbsdGthYKu4UE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38826	uniprotkb:P54790	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	intact:EBI-12576|uniprotkb:D6VXZ9|ensemblfungi:YLL004W	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:orc3_yeast(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:OAF1(gene name synonym)|uniprotkb:OIF1(gene name synonym)|uniprotkb:YLL004W(locus name)|uniprotkb:L1365(orf name)|uniprotkb:Origin recognition complex 62 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1532985|imex:IM-19741-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	ensemblfungi:YLL004W(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR018247|interpro:IPR020795|interpro:IPR040855|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|ensemblfungi:YLL004W_mRNA(transcript)|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|rcsb pdb:7MCA|refseq:NP_013097.1|sgd:S000003927|dip:DIP-2286N|mint:P54790	-	crc64:22803C70378B7E85	crc64:3FAAEE3F645D3F9C	figure legend:1 A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	rogid:OHTvxxS+UI2qEDyZ+wyi2v0nhlI559292	intact-crc:479CAF8475332A22|rigid:ZA3gbWrQCgj5+Zn40nSeP2cQTGo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38826	uniprotkb:P38826	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1532991|imex:IM-19741-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	-	crc64:22803C70378B7E85	crc64:22803C70378B7E85	figure legend:1 A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	intact-crc:1A64AAB20198D04A|rigid:PHsVNBxD7OZVK+SajfGbWtuJ8tY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50874	uniprotkb:P50874	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533000|imex:IM-19741-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	-	crc64:1FE5DE28AFF6B41C	crc64:1FE5DE28AFF6B41C	figure legend:1 A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	intact-crc:49DE22A0ABA5CA05|rigid:ebBBwELYxgKK9ZDNFxvXkOjIf/k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54790	uniprotkb:Q12495	intact:EBI-12576|uniprotkb:D6VXZ9|ensemblfungi:YLL004W	intact:EBI-3913|uniprotkb:D6W428|ensemblfungi:YPR018W	psi-mi:orc3_yeast(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:OAF1(gene name synonym)|uniprotkb:OIF1(gene name synonym)|uniprotkb:YLL004W(locus name)|uniprotkb:L1365(orf name)|uniprotkb:Origin recognition complex 62 kDa subunit(gene name synonym)	psi-mi:rlf2_yeast(display_long)|uniprotkb:RLF2(gene name)|psi-mi:RLF2(display_short)|uniprotkb:CAC1(gene name synonym)|uniprotkb:YPR018W(locus name)|uniprotkb:YP9531.12(orf name)|uniprotkb:CAF-1 90 kDa subunit(gene name synonym)|uniprotkb:RAP1 localization factor 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533260|imex:IM-19741-34	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLL004W(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR018247|interpro:IPR020795|interpro:IPR040855|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|ensemblfungi:YLL004W_mRNA(transcript)|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|rcsb pdb:7MCA|refseq:NP_013097.1|sgd:S000003927|dip:DIP-2286N|mint:P54790	refseq:NP_015343.1|sgd:S000006222|dip:DIP-923N|mint:Q12495|ensemblfungi:YPR018W(gene)|ensemblfungi:YPR018W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0033186"(CAF-1 complex)|interpro:IPR022043|rcsb pdb:5EJO|rcsb pdb:5JBM	-	crc64:3FAAEE3F645D3F9C	crc64:C593E6E4FE5FD778	figure legend:4 A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:OHTvxxS+UI2qEDyZ+wyi2v0nhlI559292	rogid:0H5tFVg8cIEf8p/PMPA5yqVTVl8559292	intact-crc:87C2D6A342BBA988|rigid:MbKhcImvje5GIg+cr7wdZl1Nsvw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50874	uniprotkb:Q12495	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	intact:EBI-3913|uniprotkb:D6W428|ensemblfungi:YPR018W	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:rlf2_yeast(display_long)|uniprotkb:RLF2(gene name)|psi-mi:RLF2(display_short)|uniprotkb:CAC1(gene name synonym)|uniprotkb:YPR018W(locus name)|uniprotkb:YP9531.12(orf name)|uniprotkb:CAF-1 90 kDa subunit(gene name synonym)|uniprotkb:RAP1 localization factor 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533266|imex:IM-19741-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	refseq:NP_015343.1|sgd:S000006222|dip:DIP-923N|mint:Q12495|ensemblfungi:YPR018W(gene)|ensemblfungi:YPR018W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0033186"(CAF-1 complex)|interpro:IPR022043|rcsb pdb:5EJO|rcsb pdb:5JBM	-	crc64:1FE5DE28AFF6B41C	crc64:C593E6E4FE5FD778	figure legend:4 A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	rogid:0H5tFVg8cIEf8p/PMPA5yqVTVl8559292	intact-crc:660B6BFA3F38DC26|rigid:ZVRYPd1/szJKuv/4wh88jAcdOnY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38826	uniprotkb:Q12495	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	intact:EBI-3913|uniprotkb:D6W428|ensemblfungi:YPR018W	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:rlf2_yeast(display_long)|uniprotkb:RLF2(gene name)|psi-mi:RLF2(display_short)|uniprotkb:CAC1(gene name synonym)|uniprotkb:YPR018W(locus name)|uniprotkb:YP9531.12(orf name)|uniprotkb:CAF-1 90 kDa subunit(gene name synonym)|uniprotkb:RAP1 localization factor 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533271|imex:IM-19741-36	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	refseq:NP_015343.1|sgd:S000006222|dip:DIP-923N|mint:Q12495|ensemblfungi:YPR018W(gene)|ensemblfungi:YPR018W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0033186"(CAF-1 complex)|interpro:IPR022043|rcsb pdb:5EJO|rcsb pdb:5JBM	-	crc64:22803C70378B7E85	crc64:C593E6E4FE5FD778	figure legend:4 A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	rogid:0H5tFVg8cIEf8p/PMPA5yqVTVl8559292	intact-crc:54B955755123CF74|rigid:qZK+kQZG5wOC4EEXvDuZmzhjinE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38826	uniprotkb:P23748	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	intact:EBI-11200|uniprotkb:D6VZL1|ensemblfungi:YMR036C	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:mpip_yeast(display_long)|uniprotkb:MIH1(gene name)|psi-mi:MIH1(display_short)|uniprotkb:YMR036C(locus name)|uniprotkb:YM9532.01C(orf name)|uniprotkb:YM9973.10C(orf name)|uniprotkb:Mitosis initiation protein MIH1(gene name synonym)|uniprotkb:Mitotic inducer homolog(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533276|imex:IM-19741-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	ensemblfungi:YMR036C(gene)|ensemblfungi:YMR036C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0110032"(positive regulation of G2/MI transition of meiotic cell cycle)|interpro:IPR000751(M-phase inducer phosphatase)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|reactome:R-SCE-69656|refseq:NP_013750.1|sgd:S000004639|reactome:R-SCE-156711|reactome:R-SCE-176187|reactome:R-SCE-5625740|reactome:R-SCE-69202|reactome:R-SCE-69273|reactome:R-SCE-69601|reactome:R-SCE-75035|reactome:R-SCE-6804115|dip:DIP-2713N	-	crc64:22803C70378B7E85	crc64:DBD85D02CF48CA6F	figure legend:4 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	rogid:u16rAnZ+C22fjdaoVw2KAigE8zg559292	intact-crc:7CA17DEBDE64A18C|rigid:o+fhfTZ7asv3YftSaArQZkKD+nU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23748	uniprotkb:P32833	intact:EBI-11200|uniprotkb:D6VZL1|ensemblfungi:YMR036C	intact:EBI-12572|uniprotkb:D6VQ60|ensemblfungi:YBR060C	psi-mi:mpip_yeast(display_long)|uniprotkb:MIH1(gene name)|psi-mi:MIH1(display_short)|uniprotkb:YMR036C(locus name)|uniprotkb:YM9532.01C(orf name)|uniprotkb:YM9973.10C(orf name)|uniprotkb:Mitosis initiation protein MIH1(gene name synonym)|uniprotkb:Mitotic inducer homolog(gene name synonym)	psi-mi:orc2_yeast(display_long)|uniprotkb:ORC2(gene name)|psi-mi:ORC2(display_short)|uniprotkb:RRR1(gene name synonym)|uniprotkb:SIR5(gene name synonym)|uniprotkb:YBR060C(locus name)|uniprotkb:YBR0523(orf name)|uniprotkb:Origin recognition complex 71 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533282|imex:IM-19741-38	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR036C(gene)|ensemblfungi:YMR036C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0110032"(positive regulation of G2/MI transition of meiotic cell cycle)|interpro:IPR000751(M-phase inducer phosphatase)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|reactome:R-SCE-69656|refseq:NP_013750.1|sgd:S000004639|reactome:R-SCE-156711|reactome:R-SCE-176187|reactome:R-SCE-5625740|reactome:R-SCE-69202|reactome:R-SCE-69273|reactome:R-SCE-69601|reactome:R-SCE-75035|reactome:R-SCE-6804115|dip:DIP-2713N	go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0005664"(nuclear origin of replication recognition complex)|ensemblfungi:YBR060C(gene)|ensemblfungi:YBR060C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|refseq:NP_009616.1|sgd:S000000264|dip:DIP-2285N|mint:P32833	-	crc64:DBD85D02CF48CA6F	crc64:486E3E5CE353807F	figure legend:4 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:u16rAnZ+C22fjdaoVw2KAigE8zg559292	rogid:DO4QfmfwiE4RgbqHp4NRl5ryJhY559292	intact-crc:98207EA3603B0552|rigid:q2u9zTOJw5YZtfSvU9upg37in2A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P23748	uniprotkb:P54790	intact:EBI-11200|uniprotkb:D6VZL1|ensemblfungi:YMR036C	intact:EBI-12576|uniprotkb:D6VXZ9|ensemblfungi:YLL004W	psi-mi:mpip_yeast(display_long)|uniprotkb:MIH1(gene name)|psi-mi:MIH1(display_short)|uniprotkb:YMR036C(locus name)|uniprotkb:YM9532.01C(orf name)|uniprotkb:YM9973.10C(orf name)|uniprotkb:Mitosis initiation protein MIH1(gene name synonym)|uniprotkb:Mitotic inducer homolog(gene name synonym)	psi-mi:orc3_yeast(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:OAF1(gene name synonym)|uniprotkb:OIF1(gene name synonym)|uniprotkb:YLL004W(locus name)|uniprotkb:L1365(orf name)|uniprotkb:Origin recognition complex 62 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533287|imex:IM-19741-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YMR036C(gene)|ensemblfungi:YMR036C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0110032"(positive regulation of G2/MI transition of meiotic cell cycle)|interpro:IPR000751(M-phase inducer phosphatase)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|reactome:R-SCE-69656|refseq:NP_013750.1|sgd:S000004639|reactome:R-SCE-156711|reactome:R-SCE-176187|reactome:R-SCE-5625740|reactome:R-SCE-69202|reactome:R-SCE-69273|reactome:R-SCE-69601|reactome:R-SCE-75035|reactome:R-SCE-6804115|dip:DIP-2713N	ensemblfungi:YLL004W(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR018247|interpro:IPR020795|interpro:IPR040855|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|ensemblfungi:YLL004W_mRNA(transcript)|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|rcsb pdb:7MCA|refseq:NP_013097.1|sgd:S000003927|dip:DIP-2286N|mint:P54790	-	crc64:DBD85D02CF48CA6F	crc64:3FAAEE3F645D3F9C	figure legend:4 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:u16rAnZ+C22fjdaoVw2KAigE8zg559292	rogid:OHTvxxS+UI2qEDyZ+wyi2v0nhlI559292	intact-crc:50CF825212C8172A|rigid:0Spl5EHDM6+nAc2+K1O0UQbx/C0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50874	uniprotkb:P23748	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	intact:EBI-11200|uniprotkb:D6VZL1|ensemblfungi:YMR036C	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:mpip_yeast(display_long)|uniprotkb:MIH1(gene name)|psi-mi:MIH1(display_short)|uniprotkb:YMR036C(locus name)|uniprotkb:YM9532.01C(orf name)|uniprotkb:YM9973.10C(orf name)|uniprotkb:Mitosis initiation protein MIH1(gene name synonym)|uniprotkb:Mitotic inducer homolog(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533292|imex:IM-19741-40	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	ensemblfungi:YMR036C(gene)|ensemblfungi:YMR036C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0110032"(positive regulation of G2/MI transition of meiotic cell cycle)|interpro:IPR000751(M-phase inducer phosphatase)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|reactome:R-SCE-69656|refseq:NP_013750.1|sgd:S000004639|reactome:R-SCE-156711|reactome:R-SCE-176187|reactome:R-SCE-5625740|reactome:R-SCE-69202|reactome:R-SCE-69273|reactome:R-SCE-69601|reactome:R-SCE-75035|reactome:R-SCE-6804115|dip:DIP-2713N	-	crc64:1FE5DE28AFF6B41C	crc64:DBD85D02CF48CA6F	figure legend:4 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	rogid:u16rAnZ+C22fjdaoVw2KAigE8zg559292	intact-crc:248C0A3E65047233|rigid:su7wXro6DRQhQNi3et6Gt8a5RDU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54791	uniprotkb:P50874	intact:EBI-12580|uniprotkb:D6W4G3|ensemblfungi:YPR162C	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	psi-mi:orc4_yeast(display_long)|uniprotkb:ORC4(gene name)|psi-mi:ORC4(display_short)|uniprotkb:YPR162C(locus name)|uniprotkb:P9325.5(orf name)|uniprotkb:Origin recognition complex 56 kDa subunit(gene name synonym)	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533015|imex:IM-19741-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR162C(gene)|ensemblfungi:YPR162C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68962|reactome:R-SCE-68949|refseq:NP_015488.1|sgd:S000006366|dip:DIP-2287N|mint:P54791	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	-	crc64:ACF064F2C633F13F	crc64:1FE5DE28AFF6B41C	figure legend:1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:kJZ5UJVsvZNFQEkBR9tmPOJ+Iv8559292	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	intact-crc:698FF91A62FF085D|rigid:VcgGZc20PLK5diO6+LXtaRXojZw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54791	uniprotkb:P50874	intact:EBI-12580|uniprotkb:D6W4G3|ensemblfungi:YPR162C	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	psi-mi:orc4_yeast(display_long)|uniprotkb:ORC4(gene name)|psi-mi:ORC4(display_short)|uniprotkb:YPR162C(locus name)|uniprotkb:P9325.5(orf name)|uniprotkb:Origin recognition complex 56 kDa subunit(gene name synonym)	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533020|imex:IM-19741-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR162C(gene)|ensemblfungi:YPR162C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68962|reactome:R-SCE-68949|refseq:NP_015488.1|sgd:S000006366|dip:DIP-2287N|mint:P54791	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	-	crc64:ACF064F2C633F13F	crc64:1FE5DE28AFF6B41C	figure legend:1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:kJZ5UJVsvZNFQEkBR9tmPOJ+Iv8559292	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	intact-crc:37BD5176A07144B1|rigid:VcgGZc20PLK5diO6+LXtaRXojZw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38826	uniprotkb:P54790	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	intact:EBI-12576|uniprotkb:D6VXZ9|ensemblfungi:YLL004W	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:orc3_yeast(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:OAF1(gene name synonym)|uniprotkb:OIF1(gene name synonym)|uniprotkb:YLL004W(locus name)|uniprotkb:L1365(orf name)|uniprotkb:Origin recognition complex 62 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533025|imex:IM-19741-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	ensemblfungi:YLL004W(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR018247|interpro:IPR020795|interpro:IPR040855|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|ensemblfungi:YLL004W_mRNA(transcript)|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|rcsb pdb:7MCA|refseq:NP_013097.1|sgd:S000003927|dip:DIP-2286N|mint:P54790	-	crc64:22803C70378B7E85	crc64:3FAAEE3F645D3F9C	figure legend:1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	rogid:OHTvxxS+UI2qEDyZ+wyi2v0nhlI559292	intact-crc:4D2609AEE75CBA72|rigid:ZA3gbWrQCgj5+Zn40nSeP2cQTGo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54790	uniprotkb:P38826	intact:EBI-12576|uniprotkb:D6VXZ9|ensemblfungi:YLL004W	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	psi-mi:orc3_yeast(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:OAF1(gene name synonym)|uniprotkb:OIF1(gene name synonym)|uniprotkb:YLL004W(locus name)|uniprotkb:L1365(orf name)|uniprotkb:Origin recognition complex 62 kDa subunit(gene name synonym)	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533030|imex:IM-19741-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLL004W(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR018247|interpro:IPR020795|interpro:IPR040855|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|ensemblfungi:YLL004W_mRNA(transcript)|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|rcsb pdb:7MCA|refseq:NP_013097.1|sgd:S000003927|dip:DIP-2286N|mint:P54790	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	-	crc64:3FAAEE3F645D3F9C	crc64:22803C70378B7E85	figure legend:1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:OHTvxxS+UI2qEDyZ+wyi2v0nhlI559292	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	intact-crc:6859DC5AFBB04BCC|rigid:ZA3gbWrQCgj5+Zn40nSeP2cQTGo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32833	uniprotkb:P54790	intact:EBI-12572|uniprotkb:D6VQ60|ensemblfungi:YBR060C	intact:EBI-12576|uniprotkb:D6VXZ9|ensemblfungi:YLL004W	psi-mi:orc2_yeast(display_long)|uniprotkb:ORC2(gene name)|psi-mi:ORC2(display_short)|uniprotkb:RRR1(gene name synonym)|uniprotkb:SIR5(gene name synonym)|uniprotkb:YBR060C(locus name)|uniprotkb:YBR0523(orf name)|uniprotkb:Origin recognition complex 71 kDa subunit(gene name synonym)	psi-mi:orc3_yeast(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:OAF1(gene name synonym)|uniprotkb:OIF1(gene name synonym)|uniprotkb:YLL004W(locus name)|uniprotkb:L1365(orf name)|uniprotkb:Origin recognition complex 62 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533035|imex:IM-19741-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0005664"(nuclear origin of replication recognition complex)|ensemblfungi:YBR060C(gene)|ensemblfungi:YBR060C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|refseq:NP_009616.1|sgd:S000000264|dip:DIP-2285N|mint:P32833	ensemblfungi:YLL004W(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR018247|interpro:IPR020795|interpro:IPR040855|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|ensemblfungi:YLL004W_mRNA(transcript)|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|rcsb pdb:7MCA|refseq:NP_013097.1|sgd:S000003927|dip:DIP-2286N|mint:P54790	-	crc64:486E3E5CE353807F	crc64:3FAAEE3F645D3F9C	figure legend:1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:DO4QfmfwiE4RgbqHp4NRl5ryJhY559292	rogid:OHTvxxS+UI2qEDyZ+wyi2v0nhlI559292	intact-crc:E9B980645963D293|rigid:DyDVTuLRgPBwiZUbsdGthYKu4UE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54790	uniprotkb:P32833	intact:EBI-12576|uniprotkb:D6VXZ9|ensemblfungi:YLL004W	intact:EBI-12572|uniprotkb:D6VQ60|ensemblfungi:YBR060C	psi-mi:orc3_yeast(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:OAF1(gene name synonym)|uniprotkb:OIF1(gene name synonym)|uniprotkb:YLL004W(locus name)|uniprotkb:L1365(orf name)|uniprotkb:Origin recognition complex 62 kDa subunit(gene name synonym)	psi-mi:orc2_yeast(display_long)|uniprotkb:ORC2(gene name)|psi-mi:ORC2(display_short)|uniprotkb:RRR1(gene name synonym)|uniprotkb:SIR5(gene name synonym)|uniprotkb:YBR060C(locus name)|uniprotkb:YBR0523(orf name)|uniprotkb:Origin recognition complex 71 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533040|imex:IM-19741-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLL004W(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR018247|interpro:IPR020795|interpro:IPR040855|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|ensemblfungi:YLL004W_mRNA(transcript)|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|rcsb pdb:7MCA|refseq:NP_013097.1|sgd:S000003927|dip:DIP-2286N|mint:P54790	go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0005664"(nuclear origin of replication recognition complex)|ensemblfungi:YBR060C(gene)|ensemblfungi:YBR060C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|refseq:NP_009616.1|sgd:S000000264|dip:DIP-2285N|mint:P32833	-	crc64:3FAAEE3F645D3F9C	crc64:486E3E5CE353807F	figure legend:1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:OHTvxxS+UI2qEDyZ+wyi2v0nhlI559292	rogid:DO4QfmfwiE4RgbqHp4NRl5ryJhY559292	intact-crc:519A8EE7889462D4|rigid:DyDVTuLRgPBwiZUbsdGthYKu4UE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38826	uniprotkb:P32833	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	intact:EBI-12572|uniprotkb:D6VQ60|ensemblfungi:YBR060C	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:orc2_yeast(display_long)|uniprotkb:ORC2(gene name)|psi-mi:ORC2(display_short)|uniprotkb:RRR1(gene name synonym)|uniprotkb:SIR5(gene name synonym)|uniprotkb:YBR060C(locus name)|uniprotkb:YBR0523(orf name)|uniprotkb:Origin recognition complex 71 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533047|imex:IM-19741-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0005664"(nuclear origin of replication recognition complex)|ensemblfungi:YBR060C(gene)|ensemblfungi:YBR060C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|refseq:NP_009616.1|sgd:S000000264|dip:DIP-2285N|mint:P32833	-	crc64:22803C70378B7E85	crc64:486E3E5CE353807F	figure legend:1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	rogid:DO4QfmfwiE4RgbqHp4NRl5ryJhY559292	intact-crc:DD73718397F07FC3|rigid:ZYTG5zpeAGvgWx3MHm3ih4HMRK4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50874	uniprotkb:P32833	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	intact:EBI-12572|uniprotkb:D6VQ60|ensemblfungi:YBR060C	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:orc2_yeast(display_long)|uniprotkb:ORC2(gene name)|psi-mi:ORC2(display_short)|uniprotkb:RRR1(gene name synonym)|uniprotkb:SIR5(gene name synonym)|uniprotkb:YBR060C(locus name)|uniprotkb:YBR0523(orf name)|uniprotkb:Origin recognition complex 71 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533052|imex:IM-19741-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0005664"(nuclear origin of replication recognition complex)|ensemblfungi:YBR060C(gene)|ensemblfungi:YBR060C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|refseq:NP_009616.1|sgd:S000000264|dip:DIP-2285N|mint:P32833	-	crc64:1FE5DE28AFF6B41C	crc64:486E3E5CE353807F	figure legend:1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	rogid:DO4QfmfwiE4RgbqHp4NRl5ryJhY559292	intact-crc:9CA94BEB922F9389|rigid:XBG9nkuF3uND+L7f5BhKl55gtBU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54791	uniprotkb:P54784	intact:EBI-12580|uniprotkb:D6W4G3|ensemblfungi:YPR162C	intact:EBI-12568|uniprotkb:D6VZA8|ensemblfungi:YML065W	psi-mi:orc4_yeast(display_long)|uniprotkb:ORC4(gene name)|psi-mi:ORC4(display_short)|uniprotkb:YPR162C(locus name)|uniprotkb:P9325.5(orf name)|uniprotkb:Origin recognition complex 56 kDa subunit(gene name synonym)	psi-mi:orc1_yeast(display_long)|uniprotkb:ORC1(gene name)|psi-mi:ORC1(display_short)|uniprotkb:YML065W(locus name)|uniprotkb:Origin recognition complex 120 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533094|imex:IM-19741-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YPR162C(gene)|ensemblfungi:YPR162C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68962|reactome:R-SCE-68949|refseq:NP_015488.1|sgd:S000006366|dip:DIP-2287N|mint:P54791	rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|rcsb pdb:6WGC|reactome:R-SCE-68949|reactome:R-SCE-68962|ensemblfungi:YML065W(gene)|ensemblfungi:YML065W_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:1M4Z|rcsb pdb:1ZBX|rcsb pdb:1ZHI|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6OM3|rcsb pdb:6RQC|refseq:NP_013646.1|sgd:S000004530|dip:DIP-2284N|mint:P54784	-	crc64:ACF064F2C633F13F	crc64:BDAA9D3E40B4B76A	figure legend:1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:kJZ5UJVsvZNFQEkBR9tmPOJ+Iv8559292	rogid:ZTOvWqU+Rxwll7cRwOUsRqJC08M559292	intact-crc:EC7331D77273401F|rigid:ZtEG42RqOjiLzz74WmPfocWnBoE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54784	uniprotkb:P54791	intact:EBI-12568|uniprotkb:D6VZA8|ensemblfungi:YML065W	intact:EBI-12580|uniprotkb:D6W4G3|ensemblfungi:YPR162C	psi-mi:orc1_yeast(display_long)|uniprotkb:ORC1(gene name)|psi-mi:ORC1(display_short)|uniprotkb:YML065W(locus name)|uniprotkb:Origin recognition complex 120 kDa subunit(gene name synonym)	psi-mi:orc4_yeast(display_long)|uniprotkb:ORC4(gene name)|psi-mi:ORC4(display_short)|uniprotkb:YPR162C(locus name)|uniprotkb:P9325.5(orf name)|uniprotkb:Origin recognition complex 56 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533098|imex:IM-19741-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|rcsb pdb:6WGC|reactome:R-SCE-68949|reactome:R-SCE-68962|ensemblfungi:YML065W(gene)|ensemblfungi:YML065W_mRNA(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0046872"(metal ion binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:1M4Z|rcsb pdb:1ZBX|rcsb pdb:1ZHI|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6OM3|rcsb pdb:6RQC|refseq:NP_013646.1|sgd:S000004530|dip:DIP-2284N|mint:P54784	ensemblfungi:YPR162C(gene)|ensemblfungi:YPR162C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68962|reactome:R-SCE-68949|refseq:NP_015488.1|sgd:S000006366|dip:DIP-2287N|mint:P54791	-	crc64:BDAA9D3E40B4B76A	crc64:ACF064F2C633F13F	figure legend:1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:ZTOvWqU+Rxwll7cRwOUsRqJC08M559292	rogid:kJZ5UJVsvZNFQEkBR9tmPOJ+Iv8559292	intact-crc:5BA3B4A8CAD72A9F|rigid:ZtEG42RqOjiLzz74WmPfocWnBoE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54790	uniprotkb:P54791	intact:EBI-12576|uniprotkb:D6VXZ9|ensemblfungi:YLL004W	intact:EBI-12580|uniprotkb:D6W4G3|ensemblfungi:YPR162C	psi-mi:orc3_yeast(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:OAF1(gene name synonym)|uniprotkb:OIF1(gene name synonym)|uniprotkb:YLL004W(locus name)|uniprotkb:L1365(orf name)|uniprotkb:Origin recognition complex 62 kDa subunit(gene name synonym)	psi-mi:orc4_yeast(display_long)|uniprotkb:ORC4(gene name)|psi-mi:ORC4(display_short)|uniprotkb:YPR162C(locus name)|uniprotkb:P9325.5(orf name)|uniprotkb:Origin recognition complex 56 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533102|imex:IM-19741-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLL004W(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR018247|interpro:IPR020795|interpro:IPR040855|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|ensemblfungi:YLL004W_mRNA(transcript)|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|rcsb pdb:7MCA|refseq:NP_013097.1|sgd:S000003927|dip:DIP-2286N|mint:P54790	ensemblfungi:YPR162C(gene)|ensemblfungi:YPR162C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR016527(Origin recognition complex, subunit 4)|interpro:IPR027417|interpro:IPR032705|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68962|reactome:R-SCE-68949|refseq:NP_015488.1|sgd:S000006366|dip:DIP-2287N|mint:P54791	-	crc64:3FAAEE3F645D3F9C	crc64:ACF064F2C633F13F	figure legend:1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:OHTvxxS+UI2qEDyZ+wyi2v0nhlI559292	rogid:kJZ5UJVsvZNFQEkBR9tmPOJ+Iv8559292	intact-crc:64CEA127FED354E3|rigid:5u5YfD/qS9g60G9l4ArG8LA7caU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54790	uniprotkb:P50874	intact:EBI-12576|uniprotkb:D6VXZ9|ensemblfungi:YLL004W	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	psi-mi:orc3_yeast(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:OAF1(gene name synonym)|uniprotkb:OIF1(gene name synonym)|uniprotkb:YLL004W(locus name)|uniprotkb:L1365(orf name)|uniprotkb:Origin recognition complex 62 kDa subunit(gene name synonym)	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533107|imex:IM-19741-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLL004W(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR018247|interpro:IPR020795|interpro:IPR040855|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|ensemblfungi:YLL004W_mRNA(transcript)|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|rcsb pdb:7MCA|refseq:NP_013097.1|sgd:S000003927|dip:DIP-2286N|mint:P54790	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	-	crc64:3FAAEE3F645D3F9C	crc64:1FE5DE28AFF6B41C	figure legend:1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:OHTvxxS+UI2qEDyZ+wyi2v0nhlI559292	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	intact-crc:E55EF25AE6C95F5F|rigid:sMU9bSuCb9qhztI4X7KdCdv7Mvo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50874	uniprotkb:P38826	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533112|imex:IM-19741-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	-	crc64:1FE5DE28AFF6B41C	crc64:22803C70378B7E85	figure legend:1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	intact-crc:10043E92FDF23517|rigid:x+3BtDa6MYZwU4cs7xa44Ipkzv0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P54790	uniprotkb:P54790	intact:EBI-12576|uniprotkb:D6VXZ9|ensemblfungi:YLL004W	intact:EBI-12576|uniprotkb:D6VXZ9|ensemblfungi:YLL004W	psi-mi:orc3_yeast(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:OAF1(gene name synonym)|uniprotkb:OIF1(gene name synonym)|uniprotkb:YLL004W(locus name)|uniprotkb:L1365(orf name)|uniprotkb:Origin recognition complex 62 kDa subunit(gene name synonym)	psi-mi:orc3_yeast(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:OAF1(gene name synonym)|uniprotkb:OIF1(gene name synonym)|uniprotkb:YLL004W(locus name)|uniprotkb:L1365(orf name)|uniprotkb:Origin recognition complex 62 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533127|imex:IM-19741-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLL004W(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR018247|interpro:IPR020795|interpro:IPR040855|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|ensemblfungi:YLL004W_mRNA(transcript)|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|rcsb pdb:7MCA|refseq:NP_013097.1|sgd:S000003927|dip:DIP-2286N|mint:P54790	ensemblfungi:YLL004W(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR018247|interpro:IPR020795|interpro:IPR040855|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|ensemblfungi:YLL004W_mRNA(transcript)|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|rcsb pdb:7MCA|refseq:NP_013097.1|sgd:S000003927|dip:DIP-2286N|mint:P54790	-	crc64:3FAAEE3F645D3F9C	crc64:3FAAEE3F645D3F9C	figure legend:1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:OHTvxxS+UI2qEDyZ+wyi2v0nhlI559292	rogid:OHTvxxS+UI2qEDyZ+wyi2v0nhlI559292	intact-crc:D39B1ABAD9AC2DDC|rigid:GdcyK8y0UlkS72J8PRolTco4wWE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P50874	uniprotkb:P50874	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533133|imex:IM-19741-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	-	crc64:1FE5DE28AFF6B41C	crc64:1FE5DE28AFF6B41C	figure legend:1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	intact-crc:A2D3A3465AF5A08E|rigid:ebBBwELYxgKK9ZDNFxvXkOjIf/k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P38826	uniprotkb:P38826	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533137|imex:IM-19741-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	-	crc64:22803C70378B7E85	crc64:22803C70378B7E85	figure legend:1 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	intact-crc:046C36E918DA8B8A|rigid:PHsVNBxD7OZVK+SajfGbWtuJ8tY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11978	uniprotkb:P32833	intact:EBI-17237|uniprotkb:D6VSK9|ensemblfungi:YDR227W	intact:EBI-12572|uniprotkb:D6VQ60|ensemblfungi:YBR060C	psi-mi:sir4_yeast(display_long)|uniprotkb:STE9(gene name synonym)|uniprotkb:SIR4(gene name)|psi-mi:SIR4(display_short)|uniprotkb:ASD1(gene name synonym)|uniprotkb:UTH2(gene name synonym)|uniprotkb:YDR227W(locus name)|uniprotkb:YD9934.12(orf name)|uniprotkb:Silent information regulator 4(gene name synonym)	psi-mi:orc2_yeast(display_long)|uniprotkb:ORC2(gene name)|psi-mi:ORC2(display_short)|uniprotkb:RRR1(gene name synonym)|uniprotkb:SIR5(gene name synonym)|uniprotkb:YBR060C(locus name)|uniprotkb:YBR0523(orf name)|uniprotkb:Origin recognition complex 71 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533207|imex:IM-19741-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010513.1|sgd:S000002635|ensemblfungi:YDR227W(gene)|ensemblfungi:YDR227W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR031556|rcsb pdb:1NYH|rcsb pdb:1PL5|rcsb pdb:4IAO|rcsb pdb:6QSZ|rcsb pdb:6QTM|rcsb pdb:6RR0|rcsb pdb:6RRV|dip:DIP-33N|mint:P11978	go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0005664"(nuclear origin of replication recognition complex)|ensemblfungi:YBR060C(gene)|ensemblfungi:YBR060C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|refseq:NP_009616.1|sgd:S000000264|dip:DIP-2285N|mint:P32833	-	crc64:9C698765964F094E	crc64:486E3E5CE353807F	figure legend:3 A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:C1HZEbdzRxwODKN1FHzmhYMCl+M559292	rogid:DO4QfmfwiE4RgbqHp4NRl5ryJhY559292	intact-crc:96C20984F0C2AE8B|rigid:IkNu92QpTBHFd8EnH13ML+x+t5g	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P40957	uniprotkb:P32833	intact:EBI-10354|ensemblfungi:YGL086W|uniprotkb:D6VU58	intact:EBI-12572|uniprotkb:D6VQ60|ensemblfungi:YBR060C	psi-mi:mad1_yeast(display_long)|uniprotkb:MAD1(gene name)|psi-mi:MAD1(display_short)|uniprotkb:Mitotic arrest deficient protein 1(gene name synonym)|uniprotkb:YGL086W(locus name)	psi-mi:orc2_yeast(display_long)|uniprotkb:ORC2(gene name)|psi-mi:ORC2(display_short)|uniprotkb:RRR1(gene name synonym)|uniprotkb:SIR5(gene name synonym)|uniprotkb:YBR060C(locus name)|uniprotkb:YBR0523(orf name)|uniprotkb:Origin recognition complex 71 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533219|imex:IM-19741-28	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000003054|ensemblfungi:YGL086W(gene)|ensemblfungi:YGL086W_mRNA(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090268"(activation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1901925"(negative regulation of protein import into nucleus during spindle assembly checkpoint)|interpro:IPR008672(Mitotic checkpoint)|refseq:NP_011429.3|dip:DIP-293N|mint:P40957	go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007220(Origin recognition complex subunit 2)|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0005664"(nuclear origin of replication recognition complex)|ensemblfungi:YBR060C(gene)|ensemblfungi:YBR060C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|refseq:NP_009616.1|sgd:S000000264|dip:DIP-2285N|mint:P32833	-	-	crc64:486E3E5CE353807F	figure legend:3 A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:KN5bSe+qhWpvc7W6Sh2IolgtLXE559292	rogid:DO4QfmfwiE4RgbqHp4NRl5ryJhY559292	intact-crc:3F97656C09814E5C|rigid:GrGcnnhxQHT9gHPeV8n8hbkKenI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12495	uniprotkb:P54790	intact:EBI-3913|uniprotkb:D6W428|ensemblfungi:YPR018W	intact:EBI-12576|uniprotkb:D6VXZ9|ensemblfungi:YLL004W	psi-mi:rlf2_yeast(display_long)|uniprotkb:RLF2(gene name)|psi-mi:RLF2(display_short)|uniprotkb:CAC1(gene name synonym)|uniprotkb:YPR018W(locus name)|uniprotkb:YP9531.12(orf name)|uniprotkb:CAF-1 90 kDa subunit(gene name synonym)|uniprotkb:RAP1 localization factor 2(gene name synonym)	psi-mi:orc3_yeast(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:OAF1(gene name synonym)|uniprotkb:OIF1(gene name synonym)|uniprotkb:YLL004W(locus name)|uniprotkb:L1365(orf name)|uniprotkb:Origin recognition complex 62 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533224|imex:IM-19741-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_015343.1|sgd:S000006222|dip:DIP-923N|mint:Q12495|ensemblfungi:YPR018W(gene)|ensemblfungi:YPR018W_mRNA(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0033186"(CAF-1 complex)|interpro:IPR022043|rcsb pdb:5EJO|rcsb pdb:5JBM	ensemblfungi:YLL004W(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR018247|interpro:IPR020795|interpro:IPR040855|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|ensemblfungi:YLL004W_mRNA(transcript)|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|rcsb pdb:7MCA|refseq:NP_013097.1|sgd:S000003927|dip:DIP-2286N|mint:P54790	-	crc64:C593E6E4FE5FD778	crc64:3FAAEE3F645D3F9C	figure legend:3 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:0H5tFVg8cIEf8p/PMPA5yqVTVl8559292	rogid:OHTvxxS+UI2qEDyZ+wyi2v0nhlI559292	intact-crc:5747F4C821F8F8F3|rigid:MbKhcImvje5GIg+cr7wdZl1Nsvw	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P36157	uniprotkb:P54790	intact:EBI-26503|uniprotkb:D6VXD7|uniprotkb:Q6Q5M8|ensemblfungi:YKR077W	intact:EBI-12576|uniprotkb:D6VXZ9|ensemblfungi:YLL004W	psi-mi:msa2_yeast(display_long)|uniprotkb:YKR077W(locus name)|uniprotkb:MSA2(gene name)|psi-mi:MSA2(display_short)|uniprotkb:MBF and SBF-associated protein 2(gene name synonym)	psi-mi:orc3_yeast(display_long)|uniprotkb:ORC3(gene name)|psi-mi:ORC3(display_short)|uniprotkb:OAF1(gene name synonym)|uniprotkb:OIF1(gene name synonym)|uniprotkb:YLL004W(locus name)|uniprotkb:L1365(orf name)|uniprotkb:Origin recognition complex 62 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533231|imex:IM-19741-30	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	sgd:S000001785|refseq:NP_013003.1|mint:P36157|dip:DIP-2702N|ensemblfungi:YKR077W(gene)|ensemblfungi:YKR077W_mRNA(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)	ensemblfungi:YLL004W(gene)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR018247|interpro:IPR020795|interpro:IPR040855|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|ensemblfungi:YLL004W_mRNA(transcript)|rcsb pdb:6WGG|rcsb pdb:6WGI|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|rcsb pdb:7MCA|refseq:NP_013097.1|sgd:S000003927|dip:DIP-2286N|mint:P54790	-	-	crc64:3FAAEE3F645D3F9C	figure legend:3 B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:9+B/TYMa+nsSzo0mpMakOucqB5A559292	rogid:OHTvxxS+UI2qEDyZ+wyi2v0nhlI559292	intact-crc:A7403AA716328764|rigid:KeoQ97+TKQmeFHxe57czpGM0tbI	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38766	uniprotkb:P50874	intact:EBI-24483|uniprotkb:D3DKX8|ensemblfungi:YHR031C	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	psi-mi:rrm3_yeast(display_long)|uniprotkb:RRM3(gene name)|psi-mi:RRM3(display_short)|uniprotkb:rDNA recombination mutation protein 3(gene name synonym)|uniprotkb:RTT104(gene name synonym)|uniprotkb:Regulation of Ty1 transposition protein 104(gene name synonym)|uniprotkb:YHR031C(locus name)	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533238|imex:IM-19741-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_011896.1|sgd:S000001073|dip:DIP-2858N|mint:P38766|ensemblfungi:YHR031C(gene)|ensemblfungi:YHR031C_mRNA(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005657"(replication fork)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0071932"(replication fork reversal)|go:"GO:0097046"(replication fork progression beyond termination site)|go:"GO:0098781"(ncRNA transcription)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010285(Protein of unknown function DUF889, eukaryote)|interpro:IPR027417|interpro:IPR028880|go:"GO:0000723"(telomere maintenance)	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	-	crc64:8E0010ABB870CAB6	crc64:1FE5DE28AFF6B41C	figure legend:3 C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:oeSWlcHOD6pwziM851GHEwR2sB0559292	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	intact-crc:BEF825619311E262|rigid:2ZvFXhfvGpdgF8aWa9wSQn1Sb+A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P09959	uniprotkb:P50874	intact:EBI-18641|uniprotkb:D6VYI6|ensemblfungi:YLR182W	intact:EBI-12584|uniprotkb:D6W0T2|ensemblfungi:YNL261W	psi-mi:swi6_yeast(display_long)|uniprotkb:SWI6(gene name)|psi-mi:SWI6(display_short)|uniprotkb:YLR182W(locus name)|uniprotkb:L9470.8(orf name)|uniprotkb:Cell-cycle box factor subunit SWI6(gene name synonym)|uniprotkb:Trans-acting activator of HO endonuclease gene(gene name synonym)|uniprotkb:MBF subunit P90(gene name synonym)	psi-mi:orc5_yeast(display_long)|uniprotkb:ORC5(gene name)|psi-mi:ORC5(display_short)|uniprotkb:YNL261W(locus name)|uniprotkb:N0834(orf name)|uniprotkb:Origin recognition complex 53 kDa subunit(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533243|imex:IM-19741-32	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YLR182W(gene)|ensemblfungi:YLR182W_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0030907"(MBF transcription complex)|go:"GO:0033309"(SBF transcription complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061408"(positive regulation of transcription from RNA polymerase II promoter in response to heat stress)|go:"GO:0071931"(positive regulation of transcription involved in G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|interpro:IPR040822|rcsb pdb:1SW6|rcsb pdb:2XFV|rcsb pdb:5XW5|refseq:NP_013283.1|sgd:S000004172|dip:DIP-598N|mint:P09959	ensemblfungi:YNL261W(gene)|ensemblfungi:YNL261W_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0031261"(DNA replication preinitiation complex)|go:"GO:0031938"(obsolete regulation of chromatin silencing at telomere)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR020796|interpro:IPR027417|rcsb pdb:5V8F|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|reactome:R-SCE-68616|reactome:R-SCE-68949|reactome:R-SCE-68962|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|refseq:NP_014138.1|sgd:S000005205|dip:DIP-2288N|mint:P50874	-	crc64:9B317FCACEEC493C	crc64:1FE5DE28AFF6B41C	figure legend:3 C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:rtovwtMGdOLKrOttgos4Ej9V160559292	rogid:iNQ8Wz9QbJKyfMFfErjd+Nta8ok559292	intact-crc:C4EF50B47C1278DC|rigid:+GkCe2uBkr6dRZRLYBKIBfbSIpA	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P38826	uniprotkb:P23748	intact:EBI-12588|uniprotkb:D3DL68|ensemblfungi:YHR118C	intact:EBI-11200|uniprotkb:D6VZL1|ensemblfungi:YMR036C	psi-mi:orc6_yeast(display_long)|uniprotkb:YHR118C(locus name)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:AAP1(gene name synonym)|uniprotkb:Origin recognition complex 50 kDa subunit(gene name synonym)|uniprotkb:ACS-associated protein 1(gene name synonym)	psi-mi:mpip_yeast(display_long)|uniprotkb:MIH1(gene name)|psi-mi:MIH1(display_short)|uniprotkb:YMR036C(locus name)|uniprotkb:YM9532.01C(orf name)|uniprotkb:YM9973.10C(orf name)|uniprotkb:Mitosis initiation protein MIH1(gene name synonym)|uniprotkb:Mitotic inducer homolog(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Matsuda et al. (2007)	pubmed:17825065|imex:IM-19741	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1533249|imex:IM-19741-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensemblfungi:YHR118C(gene)|ensemblfungi:YHR118C_mRNA(transcript)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031261"(DNA replication preinitiation complex)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR016811(Origin recognition complex, subunit 6, fungi)|rcsb pdb:5ZR1|rcsb pdb:6RQC|rcsb pdb:6WGC|rcsb pdb:6WGG|rcsb pdb:6WGI|rcsb pdb:7MCA|rcsb pdb:5V8F|refseq:NP_011986.1|sgd:S000001160|mint:P38826|dip:DIP-2289N	ensemblfungi:YMR036C(gene)|ensemblfungi:YMR036C_mRNA(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0051301"(cell division)|go:"GO:0110032"(positive regulation of G2/MI transition of meiotic cell cycle)|interpro:IPR000751(M-phase inducer phosphatase)|interpro:IPR001763(Rhodanese-like)|interpro:IPR036873|reactome:R-SCE-69656|refseq:NP_013750.1|sgd:S000004639|reactome:R-SCE-156711|reactome:R-SCE-176187|reactome:R-SCE-5625740|reactome:R-SCE-69202|reactome:R-SCE-69273|reactome:R-SCE-69601|reactome:R-SCE-75035|reactome:R-SCE-6804115|dip:DIP-2713N	-	crc64:22803C70378B7E85	crc64:DBD85D02CF48CA6F	figure legend:3 D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/18	2014/10/16	rogid:ILyMHgAPh2Rb4e5fyS3gmdVaQjk559292	rogid:u16rAnZ+C22fjdaoVw2KAigE8zg559292	intact-crc:31B2F63980284ED9|rigid:o+fhfTZ7asv3YftSaArQZkKD+nU	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)