#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9CR95	uniprotkb:O08838	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-80080	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:amph_rat(display_long)|uniprotkb:Amph(gene name)|psi-mi:Amph(display_short)|uniprotkb:Amph1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7592499|mint:MINT-5223049|imex:IM-11281-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-5223051(identity)	go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|rcsb pdb:2VJ0|rcsb pdb:5M5T|reactome:R-RNO-8856828|rgd:620274|refseq:NP_071553.1|mint:O08838|dip:DIP-30977N|mint:MINT-5223050(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:f2a f6a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:wTANhsy4BxCZYbSIhwlrr+m9Tt810116	intact-crc:7C9BA2D811159DF3|rigid:ugoMPDEZu9l5exSEYlbANmcUfWA	false	glutathione s tranferase tag:?-?(MINT-5260857)|binding-associated region:1-178(MINT-5260860)	mutation disrupting interaction:21-21(MINT-5260903)|mutation disrupting interaction:102-102(MINT-5260906)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49418	uniprotkb:Q9CR95	intact:EBI-7121510|ensembl:ENSP00000348602|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7592526|mint:MINT-5260976|imex:IM-11281-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|mint:P49418|rcsb pdb:1KY7|rcsb pdb:1UTC|rcsb pdb:3SOG|rcsb pdb:4ATM|rcsb pdb:5M5S|rcsb pdb:5M61|reactome:R-HSA-8856828|refseq:NP_001626.1|refseq:NP_647477.1|dip:DIP-40729N|mint:MINT-5260983(identity)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-5260978(identity)	-	function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms	comment:mint|function:Involved in endocytosis	figure legend:f2a f6a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	intact-crc:B4B8135F56A774C2|rigid:wvizuqsoMhggEMIP556aF4QBsxc	false	-	glutathione s tranferase tag:?-?(MINT-5260981)|binding-associated region:1-178(MINT-5260979)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9CR95	uniprotkb:O08839	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-80095	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:bin1_rat(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:Amph2(gene name synonym)|uniprotkb:Amphl(gene name synonym)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7592581|mint:MINT-5260993|imex:IM-11281-36	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-5260995(identity)	go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005768"(endosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0043196"(varicosity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060987"(lipid tube)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|rcsb pdb:1BB9|reactome:R-RNO-8856828|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|rgd:621786|refseq:NP_446411.1|mint:O08839|dip:DIP-30979N|mint:MINT-5261000(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:f2a f6a|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:xqcXQWo+FXHjCGGI0Q9agaz9LMk10116	intact-crc:B98BC14B396D3F35|rigid:/m5OOuYzOWHSZ+5/8G76Lud0mLg	false	binding-associated region:1-178(MINT-5260998)|glutathione s tranferase tag:?-?(MINT-5260996)	mutation disrupting interaction:102-102(MINT-5261007)|mutation disrupting interaction:21-21(MINT-5261001)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9D1J1	uniprotkb:O08838	intact:EBI-7592608|intact:MINT-4126596|uniprotkb:Q3U1M1|uniprotkb:Q9CV41|ensembl:ENSMUSP00000030760	intact:EBI-80080	psi-mi:necp2_mouse(display_long)|uniprotkb:Necap2(gene name)|psi-mi:Necap2(display_short)|uniprotkb:NECAP endocytosis-associated protein 2(gene name synonym)	psi-mi:amph_rat(display_long)|uniprotkb:Amph(gene name)|psi-mi:Amph(display_short)|uniprotkb:Amph1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7592627|mint:MINT-5261275|imex:IM-11281-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079659.1|ensembl:ENSMUSG00000028923(gene)|ensembl:ENSMUST00000030760(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9D1J1|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-8856825|reactome:R-MMU-8856828|mint:MINT-5261277(identity)	go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|rcsb pdb:2VJ0|rcsb pdb:5M5T|reactome:R-RNO-8856828|rgd:620274|refseq:NP_071553.1|mint:O08838|dip:DIP-30977N|mint:MINT-5261282(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:f2b f6a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:9hf6YTpQlYFB4HyGB+xkn72/8hI10090	rogid:wTANhsy4BxCZYbSIhwlrr+m9Tt810116	intact-crc:4DA951CBABB62F02|rigid:GxIuQqTLY2hfPIx+3QKT4JcQ9Bg	false	glutathione s tranferase tag:?-?(MINT-5261280)|binding-associated region:1-177(MINT-5261278)	mutation disrupting interaction:20-20(MINT-5261287)|mutation disrupting interaction:101-101(MINT-5261283)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9D1J1	uniprotkb:O08839	intact:EBI-7592608|intact:MINT-4126596|uniprotkb:Q3U1M1|uniprotkb:Q9CV41|ensembl:ENSMUSP00000030760	intact:EBI-80095	psi-mi:necp2_mouse(display_long)|uniprotkb:Necap2(gene name)|psi-mi:Necap2(display_short)|uniprotkb:NECAP endocytosis-associated protein 2(gene name synonym)	psi-mi:bin1_rat(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:Amph2(gene name synonym)|uniprotkb:Amphl(gene name synonym)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7592655|mint:MINT-5261294|imex:IM-11281-38	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079659.1|ensembl:ENSMUSG00000028923(gene)|ensembl:ENSMUST00000030760(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9D1J1|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-8856825|reactome:R-MMU-8856828|mint:MINT-5261296(identity)	go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005768"(endosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0043196"(varicosity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060987"(lipid tube)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|rcsb pdb:1BB9|reactome:R-RNO-8856828|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|rgd:621786|refseq:NP_446411.1|mint:O08839|dip:DIP-30979N|mint:MINT-5261301(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:f2a f6a|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:9hf6YTpQlYFB4HyGB+xkn72/8hI10090	rogid:xqcXQWo+FXHjCGGI0Q9agaz9LMk10116	intact-crc:5F925601F83D6651|rigid:DjKThjl0QciE+JY1gqL0mwzaCpY	false	glutathione s tranferase tag:?-?(MINT-5261299)|binding-associated region:1-177(MINT-5261297)	mutation disrupting interaction:101-101(MINT-5261302)|mutation disrupting interaction:20-20(MINT-5261312)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49418	uniprotkb:P08081	intact:EBI-7121510|ensembl:ENSP00000348602|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0	intact:EBI-916140|ensembl:ENSRNOP00000019737	psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)	psi-mi:clca_rat(display_long)|uniprotkb:Clta(gene name)|psi-mi:Clta(display_short)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7592701|mint:MINT-5262254|imex:IM-11281-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|mint:P49418|rcsb pdb:1KY7|rcsb pdb:1UTC|rcsb pdb:3SOG|rcsb pdb:4ATM|rcsb pdb:5M5S|rcsb pdb:5M61|reactome:R-HSA-8856828|refseq:NP_001626.1|refseq:NP_647477.1|dip:DIP-40729N|mint:MINT-5262256(identity)	ensembl:ENSRNOG00000014635(gene)|ensembl:ENSRNOT00000019737(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007049"(cell cycle)|go:"GO:0030118"(clathrin coat)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0042277"(peptide binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099631"(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|mint:P08081|reactome:R-RNO-177504|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|rgd:70919|refseq:NP_114180.1|refseq:XP_006238166.1|refseq:XP_006238168.1|dip:DIP-36947N|mint:MINT-5262257(identity)	-	function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms	-	figure legend:F3B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606	rogid:josnOtPnIhM+WCMg+3/jsbSvdec10116	intact-crc:7882CA8BEE420372|rigid:QlWoLMQ+xTDC7fgAcMlob6uVpqg	false	glutathione s tranferase tag:?-?(MINT-5262317)|binding-associated region:297-695(MINT-5262320)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49418	uniprotkb:P08081	intact:EBI-7121510|ensembl:ENSP00000348602|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0	intact:EBI-916140|ensembl:ENSRNOP00000019737	psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)	psi-mi:clca_rat(display_long)|uniprotkb:Clta(gene name)|psi-mi:Clta(display_short)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7592755|mint:MINT-5262504|imex:IM-11281-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|mint:P49418|rcsb pdb:1KY7|rcsb pdb:1UTC|rcsb pdb:3SOG|rcsb pdb:4ATM|rcsb pdb:5M5S|rcsb pdb:5M61|reactome:R-HSA-8856828|refseq:NP_001626.1|refseq:NP_647477.1|dip:DIP-40729N|mint:MINT-5262506(identity)	ensembl:ENSRNOG00000014635(gene)|ensembl:ENSRNOT00000019737(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007049"(cell cycle)|go:"GO:0030118"(clathrin coat)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0042277"(peptide binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099631"(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|mint:P08081|reactome:R-RNO-177504|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|rgd:70919|refseq:NP_114180.1|refseq:XP_006238166.1|refseq:XP_006238168.1|dip:DIP-36947N|mint:MINT-5262511(identity)	-	function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms	-	figure legend:F3d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606	rogid:josnOtPnIhM+WCMg+3/jsbSvdec10116	intact-crc:8D77079C5CFFDC61|rigid:QlWoLMQ+xTDC7fgAcMlob6uVpqg	false	glutathione s tranferase tag:?-?(MINT-5262509)|binding-associated region:291-360(MINT-5262507)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P69682	uniprotkb:P49418	intact:EBI-7592718|intact:MINT-5260811|uniprotkb:Q4QR67|ensembl:ENSRNOP00000013272	intact:EBI-7121510|ensembl:ENSP00000348602|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0	psi-mi:necp1_rat(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7592738|mint:MINT-5262424|imex:IM-11281-40	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001025090.1|rgd:1306053|ensembl:ENSRNOG00000009236(gene)|ensembl:ENSRNOT00000013272(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:P69682|reactome:R-RNO-432722|reactome:R-RNO-8856825|reactome:R-RNO-8856828|dip:DIP-44064N|mint:MINT-5262431(identity)	ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|mint:P49418|rcsb pdb:1KY7|rcsb pdb:1UTC|rcsb pdb:3SOG|rcsb pdb:4ATM|rcsb pdb:5M5S|rcsb pdb:5M61|reactome:R-HSA-8856828|refseq:NP_001626.1|refseq:NP_647477.1|dip:DIP-40729N|mint:MINT-5262426(identity)	-	comment:mint|function:Involved in endocytosis	function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms	figure legend:F3B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:KwuJp3lG7BL4q4Fzy7YtThmdCso10116	rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606	intact-crc:843ED06EEF4BDC31|rigid:RmlobWePmZC9IoQl1o0fSwFhbdg	false	-	binding-associated region:297-695(MINT-5262427)|glutathione s tranferase tag:?-?(MINT-5262429)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49418	uniprotkb:P08081	intact:EBI-7121510|ensembl:ENSP00000348602|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0	intact:EBI-916140|ensembl:ENSRNOP00000019737	psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)	psi-mi:clca_rat(display_long)|uniprotkb:Clta(gene name)|psi-mi:Clta(display_short)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7592772|mint:MINT-5262512|imex:IM-11281-42	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|mint:P49418|rcsb pdb:1KY7|rcsb pdb:1UTC|rcsb pdb:3SOG|rcsb pdb:4ATM|rcsb pdb:5M5S|rcsb pdb:5M61|reactome:R-HSA-8856828|refseq:NP_001626.1|refseq:NP_647477.1|dip:DIP-40729N|mint:MINT-5262514(identity)	ensembl:ENSRNOG00000014635(gene)|ensembl:ENSRNOT00000019737(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007049"(cell cycle)|go:"GO:0030118"(clathrin coat)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0042277"(peptide binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099631"(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|mint:P08081|reactome:R-RNO-177504|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|rgd:70919|refseq:NP_114180.1|refseq:XP_006238166.1|refseq:XP_006238168.1|dip:DIP-36947N|mint:MINT-5262519(identity)	-	function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms	-	figure legend:F3d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606	rogid:josnOtPnIhM+WCMg+3/jsbSvdec10116	intact-crc:5B72A0925CF47A11|rigid:QlWoLMQ+xTDC7fgAcMlob6uVpqg	false	glutathione s tranferase tag:?-?(MINT-5262515)|binding-associated region:351-445(MINT-5262517)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49418	uniprotkb:P69682	intact:EBI-7121510|ensembl:ENSP00000348602|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0	intact:EBI-7592718|intact:MINT-5260811|uniprotkb:Q4QR67|ensembl:ENSRNOP00000013272	psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)	psi-mi:necp1_rat(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7592789|mint:MINT-5262539|imex:IM-11281-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|mint:P49418|rcsb pdb:1KY7|rcsb pdb:1UTC|rcsb pdb:3SOG|rcsb pdb:4ATM|rcsb pdb:5M5S|rcsb pdb:5M61|reactome:R-HSA-8856828|refseq:NP_001626.1|refseq:NP_647477.1|dip:DIP-40729N|mint:MINT-5262541(identity)	refseq:NP_001025090.1|rgd:1306053|ensembl:ENSRNOG00000009236(gene)|ensembl:ENSRNOT00000013272(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:P69682|reactome:R-RNO-432722|reactome:R-RNO-8856825|reactome:R-RNO-8856828|dip:DIP-44064N|mint:MINT-5262546(identity)	-	function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms	comment:mint|function:Involved in endocytosis	figure legend:f3d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606	rogid:KwuJp3lG7BL4q4Fzy7YtThmdCso10116	intact-crc:0D812D5561900D57|rigid:RmlobWePmZC9IoQl1o0fSwFhbdg	false	binding-associated region:291-329(MINT-5262544)|glutathione s tranferase tag:?-?(MINT-5262542)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P69682	uniprotkb:P49418	intact:EBI-7592718|intact:MINT-5260811|uniprotkb:Q4QR67|ensembl:ENSRNOP00000013272	intact:EBI-7121510|ensembl:ENSP00000348602|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0	psi-mi:necp1_rat(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7592824|mint:MINT-5262553|imex:IM-11281-44	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001025090.1|rgd:1306053|ensembl:ENSRNOG00000009236(gene)|ensembl:ENSRNOT00000013272(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:P69682|reactome:R-RNO-432722|reactome:R-RNO-8856825|reactome:R-RNO-8856828|dip:DIP-44064N|mint:MINT-5262560(identity)	ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|mint:P49418|rcsb pdb:1KY7|rcsb pdb:1UTC|rcsb pdb:3SOG|rcsb pdb:4ATM|rcsb pdb:5M5S|rcsb pdb:5M61|reactome:R-HSA-8856828|refseq:NP_001626.1|refseq:NP_647477.1|dip:DIP-40729N|mint:MINT-5262555(identity)	-	comment:mint|function:Involved in endocytosis	function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms	figure legend:F3d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:KwuJp3lG7BL4q4Fzy7YtThmdCso10116	rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606	intact-crc:30EDD5A95500C35F|rigid:RmlobWePmZC9IoQl1o0fSwFhbdg	false	-	glutathione s tranferase tag:?-?(MINT-5262558)|binding-associated region:324-445(MINT-5262556)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P58197	uniprotkb:P49418	intact:EBI-7069641|intact:MINT-5262844	intact:EBI-7121510|ensembl:ENSP00000348602|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0	psi-mi:ap2a_rat(display_long)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:Tfap2a(gene name)|psi-mi:Tfap2a(display_short)|uniprotkb:Tcfap2a(gene name synonym)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym)	psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7592878|mint:MINT-5262894|imex:IM-11281-46	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P58197|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014032"(neural crest cell development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0021506"(anterior neuropore closure)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043588"(skin development)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071711"(basement membrane organization)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|reactome:R-RNO-8864260|reactome:R-RNO-8866904|reactome:R-RNO-8866907|reactome:R-RNO-8869496|go:"GO:0072210"(metanephric nephron development)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|rgd:1310267|interpro:IPR013854(Transcription factor AP-2, C-terminal)|mint:MINT-5262901(identity)	ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|mint:P49418|rcsb pdb:1KY7|rcsb pdb:1UTC|rcsb pdb:3SOG|rcsb pdb:4ATM|rcsb pdb:5M5S|rcsb pdb:5M61|reactome:R-HSA-8856828|refseq:NP_001626.1|refseq:NP_647477.1|dip:DIP-40729N|mint:MINT-5262896(identity)	-	comment:mint|function:Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and c-Myc. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle	function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms	figure legend:F3d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:oeWxfD0s7oOqM/z8+goxvVCml6810116	rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606	intact-crc:8A6DF334B646CF57|rigid:pQIq/SbOOPEhvg3mozETcfNMhMc	false	-	binding-associated region:291-329(MINT-5262897)|glutathione s tranferase tag:?-?(MINT-5262899)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P49418	uniprotkb:P58197	intact:EBI-7121510|ensembl:ENSP00000348602|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0	intact:EBI-7069641|intact:MINT-5262844	psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)	psi-mi:ap2a_rat(display_long)|uniprotkb:Activating enhancer-binding protein 2-alpha(gene name synonym)|uniprotkb:Tfap2a(gene name)|psi-mi:Tfap2a(display_short)|uniprotkb:Tcfap2a(gene name synonym)|uniprotkb:AP-2 transcription factor(gene name synonym)|uniprotkb:Activator protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7592841|mint:MINT-5262742|imex:IM-11281-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|mint:P49418|rcsb pdb:1KY7|rcsb pdb:1UTC|rcsb pdb:3SOG|rcsb pdb:4ATM|rcsb pdb:5M5S|rcsb pdb:5M61|reactome:R-HSA-8856828|refseq:NP_001626.1|refseq:NP_647477.1|dip:DIP-40729N|mint:MINT-5262744(identity)	mint:P58197|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0001843"(neural tube closure)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003404"(optic vesicle morphogenesis)|go:"GO:0003409"(optic cup structural organization)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0007423"(sensory organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010172"(embryonic body morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010842"(retina layer formation)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014032"(neural crest cell development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0021506"(anterior neuropore closure)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021623"(oculomotor nerve formation)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043588"(skin development)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048485"(sympathetic nervous system development)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048730"(epidermis morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060235"(lens induction in camera-type eye)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061303"(cornea development in camera-type eye)|go:"GO:0070172"(positive regulation of tooth mineralization)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071711"(basement membrane organization)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|reactome:R-RNO-8864260|reactome:R-RNO-8866904|reactome:R-RNO-8866907|reactome:R-RNO-8869496|go:"GO:0072210"(metanephric nephron development)|go:"GO:0140536"(nuclear receptor corepressor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004979(Transcription factor AP-2)|interpro:IPR008121(Transcription factor AP-2 alpha, N-terminal)|rgd:1310267|interpro:IPR013854(Transcription factor AP-2, C-terminal)|mint:MINT-5262749(identity)	-	function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms	comment:mint|function:Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and c-Myc. AP-2 alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle	figure legend:F3d|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606	rogid:oeWxfD0s7oOqM/z8+goxvVCml6810116	intact-crc:B7010BC882D6015F|rigid:pQIq/SbOOPEhvg3mozETcfNMhMc	false	glutathione s tranferase tag:?-?(MINT-5262745)|binding-associated region:324-445(MINT-5262747)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49418	uniprotkb:Q9CR95	intact:EBI-7121510|ensembl:ENSP00000348602|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7592895|mint:MINT-6168166|imex:IM-11281-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|mint:P49418|rcsb pdb:1KY7|rcsb pdb:1UTC|rcsb pdb:3SOG|rcsb pdb:4ATM|rcsb pdb:5M5S|rcsb pdb:5M61|reactome:R-HSA-8856828|refseq:NP_001626.1|refseq:NP_647477.1|dip:DIP-40729N|mint:MINT-6168168(identity)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168173(identity)	-	function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms	comment:mint|function:Involved in endocytosis	figure legend:F4C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	intact-crc:330E111D776D8AC7|rigid:wvizuqsoMhggEMIP556aF4QBsxc	false	mutation disrupting interaction:322-322,324-324,328-328(MINT-6168186)|glutathione s tranferase tag:?-?(MINT-6168169)|binding-associated region:311-329(MINT-6168171)	his tag:?-?(MINT-6168192)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P49418	uniprotkb:P17427	intact:EBI-7121510|ensembl:ENSP00000348602|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0	intact:EBI-775215|uniprotkb:Q8C2J5|uniprotkb:Q921V0|ensembl:ENSMUSP00000003038	psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)	psi-mi:ap2a2_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Ap2a2(gene name)|psi-mi:Ap2a2(display_short)|uniprotkb:Adtab(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7592942|mint:MINT-6168411|imex:IM-11281-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|mint:P49418|rcsb pdb:1KY7|rcsb pdb:1UTC|rcsb pdb:3SOG|rcsb pdb:4ATM|rcsb pdb:5M5S|rcsb pdb:5M61|reactome:R-HSA-8856828|refseq:NP_001626.1|refseq:NP_647477.1|dip:DIP-40729N|mint:MINT-6168413(identity)	refseq:NP_031485.3|dip:DIP-32160N|ensembl:ENSMUSG00000002957(gene)|ensembl:ENSMUST00000003038(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030141"(secretory granule)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17427|rcsb pdb:1B9K|rcsb pdb:1KY6|rcsb pdb:1KY7|rcsb pdb:1KYD|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QTP|rcsb pdb:1QTS|rcsb pdb:1W80|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2VJ0|rcsb pdb:3HS8|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-6798695|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|mint:MINT-6168422(identity)	-	function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms	-	figure legend:F4C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606	rogid:KlOjm5d8qxxQkcuD2Hukoj8DLss10090	intact-crc:8ED21E0D967ABFC7|rigid:b9sxAc6dbrZrMmtvObaNPpn7+sI	false	binding-associated region:321-329(MINT-6168418)|mutation decreasing interaction:322-322(MINT-6168425)|glutathione s tranferase tag:?-?(MINT-6168420)|mutation disrupting interaction:324-324,328-328(MINT-6168414)	his tag:?-?(MINT-6168423)|binding-associated region:701-938(MINT-6168430)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9CR95	uniprotkb:O08838	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-80080	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:amph_rat(display_long)|uniprotkb:Amph(gene name)|psi-mi:Amph(display_short)|uniprotkb:Amph1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7592979|mint:MINT-6168439|imex:IM-11281-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168441(identity)	go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|rcsb pdb:2VJ0|rcsb pdb:5M5T|reactome:R-RNO-8856828|rgd:620274|refseq:NP_071553.1|mint:O08838|dip:DIP-30977N|mint:MINT-6168451(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:F5E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:wTANhsy4BxCZYbSIhwlrr+m9Tt810116	intact-crc:BF1A698871127B69|rigid:KacOaEevugConr7OXVcDgoYDE7o	false	binding-associated region:1-133(MINT-6168442)|glutathione s tranferase tag:?-?(MINT-6168444)|mutation disrupting interaction:21-21(MINT-6168455)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CR95	uniprotkb:O08839	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-80095	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:bin1_rat(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:Amph2(gene name synonym)|uniprotkb:Amphl(gene name synonym)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7592979|mint:MINT-6168439|imex:IM-11281-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168441(identity)	go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005768"(endosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0043196"(varicosity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060987"(lipid tube)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|rcsb pdb:1BB9|reactome:R-RNO-8856828|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|rgd:621786|refseq:NP_446411.1|mint:O08839|dip:DIP-30979N|mint:MINT-6168446(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:F5E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:xqcXQWo+FXHjCGGI0Q9agaz9LMk10116	intact-crc:BF1A698871127B69|rigid:KacOaEevugConr7OXVcDgoYDE7o	false	binding-associated region:1-133(MINT-6168442)|glutathione s tranferase tag:?-?(MINT-6168444)|mutation disrupting interaction:21-21(MINT-6168455)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CR95	uniprotkb:O08838	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-80080	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:amph_rat(display_long)|uniprotkb:Amph(gene name)|psi-mi:Amph(display_short)|uniprotkb:Amph1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593022|mint:MINT-6168473|imex:IM-11281-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168475(identity)	go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|rcsb pdb:2VJ0|rcsb pdb:5M5T|reactome:R-RNO-8856828|rgd:620274|refseq:NP_071553.1|mint:O08838|dip:DIP-30977N|mint:MINT-6168484(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:F5E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:wTANhsy4BxCZYbSIhwlrr+m9Tt810116	intact-crc:F5DD298E89915E21|rigid:KacOaEevugConr7OXVcDgoYDE7o	false	binding-associated region:1-133(MINT-6168476)|glutathione s tranferase tag:?-?(MINT-6168479)|mutation disrupting interaction:95-95(MINT-6168481)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CR95	uniprotkb:O08839	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-80095	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:bin1_rat(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:Amph2(gene name synonym)|uniprotkb:Amphl(gene name synonym)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593022|mint:MINT-6168473|imex:IM-11281-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168475(identity)	go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005768"(endosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0043196"(varicosity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060987"(lipid tube)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|rcsb pdb:1BB9|reactome:R-RNO-8856828|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|rgd:621786|refseq:NP_446411.1|mint:O08839|dip:DIP-30979N|mint:MINT-6168483(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:F5E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:xqcXQWo+FXHjCGGI0Q9agaz9LMk10116	intact-crc:F5DD298E89915E21|rigid:KacOaEevugConr7OXVcDgoYDE7o	false	binding-associated region:1-133(MINT-6168476)|glutathione s tranferase tag:?-?(MINT-6168479)|mutation disrupting interaction:95-95(MINT-6168481)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CR95	uniprotkb:O08838	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-80080	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:amph_rat(display_long)|uniprotkb:Amph(gene name)|psi-mi:Amph(display_short)|uniprotkb:Amph1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593047|mint:MINT-6168497|imex:IM-11281-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168499(identity)	go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|rcsb pdb:2VJ0|rcsb pdb:5M5T|reactome:R-RNO-8856828|rgd:620274|refseq:NP_071553.1|mint:O08838|dip:DIP-30977N|mint:MINT-6168508(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:F5E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:wTANhsy4BxCZYbSIhwlrr+m9Tt810116	intact-crc:35BC39557F2DE0AA|rigid:KacOaEevugConr7OXVcDgoYDE7o	false	mutation disrupting interaction:102-102(MINT-6168505)|glutathione s tranferase tag:?-?(MINT-6168503)|binding-associated region:1-133(MINT-6168500)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CR95	uniprotkb:O08839	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-80095	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:bin1_rat(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:Amph2(gene name synonym)|uniprotkb:Amphl(gene name synonym)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593047|mint:MINT-6168497|imex:IM-11281-12	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168499(identity)	go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005768"(endosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0043196"(varicosity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060987"(lipid tube)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|rcsb pdb:1BB9|reactome:R-RNO-8856828|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|rgd:621786|refseq:NP_446411.1|mint:O08839|dip:DIP-30979N|mint:MINT-6168507(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:F5E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:xqcXQWo+FXHjCGGI0Q9agaz9LMk10116	intact-crc:35BC39557F2DE0AA|rigid:KacOaEevugConr7OXVcDgoYDE7o	false	mutation disrupting interaction:102-102(MINT-6168505)|glutathione s tranferase tag:?-?(MINT-6168503)|binding-associated region:1-133(MINT-6168500)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CR95	uniprotkb:O08838	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-80080	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:amph_rat(display_long)|uniprotkb:Amph(gene name)|psi-mi:Amph(display_short)|uniprotkb:Amph1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593072|mint:MINT-6168530|imex:IM-11281-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168532(identity)	go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|rcsb pdb:2VJ0|rcsb pdb:5M5T|reactome:R-RNO-8856828|rgd:620274|refseq:NP_071553.1|mint:O08838|dip:DIP-30977N|mint:MINT-6168541(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:F5E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:wTANhsy4BxCZYbSIhwlrr+m9Tt810116	intact-crc:EFA1B7BE440175E4|rigid:KacOaEevugConr7OXVcDgoYDE7o	false	glutathione s tranferase tag:?-?(MINT-6168536)|binding-associated region:1-133(MINT-6168533)|mutation decreasing interaction:102-102(MINT-6168538)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CR95	uniprotkb:O08839	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-80095	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:bin1_rat(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:Amph2(gene name synonym)|uniprotkb:Amphl(gene name synonym)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593072|mint:MINT-6168530|imex:IM-11281-14	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168532(identity)	go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005768"(endosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0043196"(varicosity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060987"(lipid tube)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|rcsb pdb:1BB9|reactome:R-RNO-8856828|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|rgd:621786|refseq:NP_446411.1|mint:O08839|dip:DIP-30979N|mint:MINT-6168540(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:F5E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:xqcXQWo+FXHjCGGI0Q9agaz9LMk10116	intact-crc:EFA1B7BE440175E4|rigid:KacOaEevugConr7OXVcDgoYDE7o	false	glutathione s tranferase tag:?-?(MINT-6168536)|binding-associated region:1-133(MINT-6168533)|mutation decreasing interaction:102-102(MINT-6168538)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CR95	uniprotkb:O08839	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-80095	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:bin1_rat(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:Amph2(gene name synonym)|uniprotkb:Amphl(gene name synonym)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593147|mint:MINT-6168542|imex:IM-11281-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168544(identity)	go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005768"(endosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0043196"(varicosity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060987"(lipid tube)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|rcsb pdb:1BB9|reactome:R-RNO-8856828|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|rgd:621786|refseq:NP_446411.1|mint:O08839|dip:DIP-30979N|mint:MINT-6168553(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:F5E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:xqcXQWo+FXHjCGGI0Q9agaz9LMk10116	intact-crc:B7840613024338EF|rigid:KacOaEevugConr7OXVcDgoYDE7o	false	binding-associated region:1-133(MINT-6168549)|mutation decreasing interaction:98-98(MINT-6168545)|glutathione s tranferase tag:?-?(MINT-6168547)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CR95	uniprotkb:O08838	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-80080	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:amph_rat(display_long)|uniprotkb:Amph(gene name)|psi-mi:Amph(display_short)|uniprotkb:Amph1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593147|mint:MINT-6168542|imex:IM-11281-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168544(identity)	go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|rcsb pdb:2VJ0|rcsb pdb:5M5T|reactome:R-RNO-8856828|rgd:620274|refseq:NP_071553.1|mint:O08838|dip:DIP-30977N|mint:MINT-6168552(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:F5E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:wTANhsy4BxCZYbSIhwlrr+m9Tt810116	intact-crc:B7840613024338EF|rigid:KacOaEevugConr7OXVcDgoYDE7o	false	binding-associated region:1-133(MINT-6168549)|mutation decreasing interaction:98-98(MINT-6168545)|glutathione s tranferase tag:?-?(MINT-6168547)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CR95	uniprotkb:O08838	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-80080	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:amph_rat(display_long)|uniprotkb:Amph(gene name)|psi-mi:Amph(display_short)|uniprotkb:Amph1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593172|mint:MINT-6168566|imex:IM-11281-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168568(identity)	go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|rcsb pdb:2VJ0|rcsb pdb:5M5T|reactome:R-RNO-8856828|rgd:620274|refseq:NP_071553.1|mint:O08838|dip:DIP-30977N|mint:MINT-6168576(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:F5E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:wTANhsy4BxCZYbSIhwlrr+m9Tt810116	intact-crc:2D9DE1D0A1E0FA15|rigid:KacOaEevugConr7OXVcDgoYDE7o	false	glutathione s tranferase tag:?-?(MINT-6168571)|mutation decreasing interaction:70-70(MINT-6168569)|binding-associated region:1-133(MINT-6168573)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CR95	uniprotkb:O08839	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-80095	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:bin1_rat(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:Amph2(gene name synonym)|uniprotkb:Amphl(gene name synonym)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593172|mint:MINT-6168566|imex:IM-11281-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168568(identity)	go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005768"(endosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0043196"(varicosity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060987"(lipid tube)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|rcsb pdb:1BB9|reactome:R-RNO-8856828|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|rgd:621786|refseq:NP_446411.1|mint:O08839|dip:DIP-30979N|mint:MINT-6168577(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:F5E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:xqcXQWo+FXHjCGGI0Q9agaz9LMk10116	intact-crc:2D9DE1D0A1E0FA15|rigid:KacOaEevugConr7OXVcDgoYDE7o	false	glutathione s tranferase tag:?-?(MINT-6168571)|mutation decreasing interaction:70-70(MINT-6168569)|binding-associated region:1-133(MINT-6168573)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17427	uniprotkb:O88339	intact:EBI-775215|uniprotkb:Q8C2J5|uniprotkb:Q921V0|ensembl:ENSMUSP00000003038	intact:EBI-7066728|intact:MINT-101104	psi-mi:ap2a2_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Ap2a2(gene name)|psi-mi:Ap2a2(display_short)|uniprotkb:Adtab(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	psi-mi:epn1_rat(display_long)|uniprotkb:Epn1(gene name)|psi-mi:Epn1(display_short)|uniprotkb:EPS-15-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593197|mint:MINT-6168614|imex:IM-11281-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_031485.3|dip:DIP-32160N|ensembl:ENSMUSG00000002957(gene)|ensembl:ENSMUST00000003038(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030141"(secretory granule)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17427|rcsb pdb:1B9K|rcsb pdb:1KY6|rcsb pdb:1KY7|rcsb pdb:1KYD|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QTP|rcsb pdb:1QTS|rcsb pdb:1W80|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2VJ0|rcsb pdb:3HS8|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-6798695|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|mint:MINT-6168618(identity)	mint:O88339|go:"GO:1905445"(positive regulation of clathrin coat assembly)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:1EDU|rcsb pdb:1EYH|rcsb pdb:1H0A|rcsb pdb:1KY6|reactome:R-RNO-182971|reactome:R-RNO-8856825|reactome:R-RNO-8856828|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0090148"(membrane fission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|rgd:619772|refseq:NP_476477.1|dip:DIP-40738N|mint:MINT-6168623(identity)	-	-	comment:mint|function:"Binds to membranes enriched in phosphatidylinositol-4,5-biphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis"	figure legend:F6A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:KlOjm5d8qxxQkcuD2Hukoj8DLss10090	rogid:HSxImXvS6/UJyI9kGWz36B0oxiM10116	intact-crc:701C45460D433506|rigid:q9r10ry+n6odZt7zt55KKPAsbC8	false	binding-associated region:701-938(MINT-6168628)|glutathione s tranferase tag:?-?(MINT-6168625)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17427	uniprotkb:P69682	intact:EBI-775215|uniprotkb:Q8C2J5|uniprotkb:Q921V0|ensembl:ENSMUSP00000003038	intact:EBI-7592718|intact:MINT-5260811|uniprotkb:Q4QR67|ensembl:ENSRNOP00000013272	psi-mi:ap2a2_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Ap2a2(gene name)|psi-mi:Ap2a2(display_short)|uniprotkb:Adtab(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	psi-mi:necp1_rat(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593197|mint:MINT-6168614|imex:IM-11281-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_031485.3|dip:DIP-32160N|ensembl:ENSMUSG00000002957(gene)|ensembl:ENSMUST00000003038(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030141"(secretory granule)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17427|rcsb pdb:1B9K|rcsb pdb:1KY6|rcsb pdb:1KY7|rcsb pdb:1KYD|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QTP|rcsb pdb:1QTS|rcsb pdb:1W80|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2VJ0|rcsb pdb:3HS8|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-6798695|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|mint:MINT-6168618(identity)	refseq:NP_001025090.1|rgd:1306053|ensembl:ENSRNOG00000009236(gene)|ensembl:ENSRNOT00000013272(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:P69682|reactome:R-RNO-432722|reactome:R-RNO-8856825|reactome:R-RNO-8856828|dip:DIP-44064N|mint:MINT-6168619(identity)	-	-	comment:mint|function:Involved in endocytosis	figure legend:F6A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:KlOjm5d8qxxQkcuD2Hukoj8DLss10090	rogid:KwuJp3lG7BL4q4Fzy7YtThmdCso10116	intact-crc:701C45460D433506|rigid:q9r10ry+n6odZt7zt55KKPAsbC8	false	binding-associated region:701-938(MINT-6168628)|glutathione s tranferase tag:?-?(MINT-6168625)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17427	uniprotkb:Q62910-1	intact:EBI-775215|uniprotkb:Q8C2J5|uniprotkb:Q921V0|ensembl:ENSMUSP00000003038	intact:EBI-7593203|intact:MINT-128591|ensembl:ENSRNOP00000060346	psi-mi:ap2a2_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Ap2a2(gene name)|psi-mi:Ap2a2(display_short)|uniprotkb:Adtab(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	psi-mi:q62910-1(display_long)|uniprotkb:Synj1(gene name)|psi-mi:Synj1(display_short)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1(gene name synonym)|uniprotkb:170 kDa(isoform synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593197|mint:MINT-6168614|imex:IM-11281-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_031485.3|dip:DIP-32160N|ensembl:ENSMUSG00000002957(gene)|ensembl:ENSMUST00000003038(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030141"(secretory granule)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17427|rcsb pdb:1B9K|rcsb pdb:1KY6|rcsb pdb:1KY7|rcsb pdb:1KYD|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QTP|rcsb pdb:1QTS|rcsb pdb:1W80|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2VJ0|rcsb pdb:3HS8|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-6798695|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|mint:MINT-6168618(identity)	intact:EBI-1149123(isoform-parent)|ensembl:ENSRNOG00000002051(gene)|ensembl:ENSRNOT00000065535(transcript)|mint:MINT-6168622(identity)	-	-	isoform-comment:A stop codon in position 1309 is suppressed due to alternative splicing|comment:mint	figure legend:F6A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:KlOjm5d8qxxQkcuD2Hukoj8DLss10090	rogid:EJnYHctzzxfhvA7evwx+c2HKuIE10116	intact-crc:701C45460D433506|rigid:q9r10ry+n6odZt7zt55KKPAsbC8	false	binding-associated region:701-938(MINT-6168628)|glutathione s tranferase tag:?-?(MINT-6168625)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17427	uniprotkb:O08839	intact:EBI-775215|uniprotkb:Q8C2J5|uniprotkb:Q921V0|ensembl:ENSMUSP00000003038	intact:EBI-80095	psi-mi:ap2a2_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Ap2a2(gene name)|psi-mi:Ap2a2(display_short)|uniprotkb:Adtab(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	psi-mi:bin1_rat(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:Amph2(gene name synonym)|uniprotkb:Amphl(gene name synonym)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593197|mint:MINT-6168614|imex:IM-11281-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_031485.3|dip:DIP-32160N|ensembl:ENSMUSG00000002957(gene)|ensembl:ENSMUST00000003038(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030141"(secretory granule)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17427|rcsb pdb:1B9K|rcsb pdb:1KY6|rcsb pdb:1KY7|rcsb pdb:1KYD|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QTP|rcsb pdb:1QTS|rcsb pdb:1W80|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2VJ0|rcsb pdb:3HS8|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-6798695|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|mint:MINT-6168618(identity)	go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005768"(endosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0043196"(varicosity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060987"(lipid tube)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|rcsb pdb:1BB9|reactome:R-RNO-8856828|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|rgd:621786|refseq:NP_446411.1|mint:O08839|dip:DIP-30979N|mint:MINT-6168616(identity)	-	-	-	figure legend:F6A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:KlOjm5d8qxxQkcuD2Hukoj8DLss10090	rogid:xqcXQWo+FXHjCGGI0Q9agaz9LMk10116	intact-crc:701C45460D433506|rigid:q9r10ry+n6odZt7zt55KKPAsbC8	false	binding-associated region:701-938(MINT-6168628)|glutathione s tranferase tag:?-?(MINT-6168625)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17427	uniprotkb:O08838	intact:EBI-775215|uniprotkb:Q8C2J5|uniprotkb:Q921V0|ensembl:ENSMUSP00000003038	intact:EBI-80080	psi-mi:ap2a2_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Ap2a2(gene name)|psi-mi:Ap2a2(display_short)|uniprotkb:Adtab(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	psi-mi:amph_rat(display_long)|uniprotkb:Amph(gene name)|psi-mi:Amph(display_short)|uniprotkb:Amph1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593197|mint:MINT-6168614|imex:IM-11281-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_031485.3|dip:DIP-32160N|ensembl:ENSMUSG00000002957(gene)|ensembl:ENSMUST00000003038(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030141"(secretory granule)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17427|rcsb pdb:1B9K|rcsb pdb:1KY6|rcsb pdb:1KY7|rcsb pdb:1KYD|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QTP|rcsb pdb:1QTS|rcsb pdb:1W80|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2VJ0|rcsb pdb:3HS8|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-6798695|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|mint:MINT-6168618(identity)	go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|rcsb pdb:2VJ0|rcsb pdb:5M5T|reactome:R-RNO-8856828|rgd:620274|refseq:NP_071553.1|mint:O08838|dip:DIP-30977N|mint:MINT-6168617(identity)	-	-	-	figure legend:F6A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:KlOjm5d8qxxQkcuD2Hukoj8DLss10090	rogid:wTANhsy4BxCZYbSIhwlrr+m9Tt810116	intact-crc:701C45460D433506|rigid:q9r10ry+n6odZt7zt55KKPAsbC8	false	binding-associated region:701-938(MINT-6168628)|glutathione s tranferase tag:?-?(MINT-6168625)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17427	uniprotkb:Q05140	intact:EBI-775215|uniprotkb:Q8C2J5|uniprotkb:Q921V0|ensembl:ENSMUSP00000003038	intact:EBI-1374805	psi-mi:ap2a2_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Ap2a2(gene name)|psi-mi:Ap2a2(display_short)|uniprotkb:Adtab(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	psi-mi:ap180_rat(display_long)|uniprotkb:Snap91(gene name)|psi-mi:Snap91(display_short)|uniprotkb:Clathrin coat-associated protein AP180(gene name synonym)|uniprotkb:91 kDa synaptosomal-associated protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593197|mint:MINT-6168614|imex:IM-11281-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_031485.3|dip:DIP-32160N|ensembl:ENSMUSG00000002957(gene)|ensembl:ENSMUST00000003038(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030141"(secretory granule)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17427|rcsb pdb:1B9K|rcsb pdb:1KY6|rcsb pdb:1KY7|rcsb pdb:1KYD|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QTP|rcsb pdb:1QTS|rcsb pdb:1W80|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2VJ0|rcsb pdb:3HS8|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-6798695|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|mint:MINT-6168618(identity)	rgd:69276|refseq:NP_113916.1|interpro:IPR011417(ANTH)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|mint:Q05140|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098894"(extrinsic component of presynaptic endocytic zone membrane)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1900275"(negative regulation of phospholipase C activity)|go:"GO:1904006"(negative regulation of phospholipase D activity)|go:"GO:1905445"(positive regulation of clathrin coat assembly)|go:"GO:2000331"(regulation of terminal button organization)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|reactome:R-RNO-8856825|reactome:R-RNO-8856828|go:"GO:0000149"(SNARE binding)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043679"(axon terminus)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048666"(neuron development)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051899"(membrane depolarization)|interpro:IPR030428|mint:MINT-6168620(identity)	-	-	-	figure legend:F6A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:KlOjm5d8qxxQkcuD2Hukoj8DLss10090	rogid:LXxIlR8jL+mLJ94McATz+sj4xF410116	intact-crc:701C45460D433506|rigid:q9r10ry+n6odZt7zt55KKPAsbC8	false	binding-associated region:701-938(MINT-6168628)|glutathione s tranferase tag:?-?(MINT-6168625)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P17427	uniprotkb:A7BFV9	intact:EBI-775215|uniprotkb:Q8C2J5|uniprotkb:Q921V0|ensembl:ENSMUSP00000003038	intact:EBI-6095043	psi-mi:ap2a2_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Ap2a2(gene name)|psi-mi:Ap2a2(display_short)|uniprotkb:Adtab(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	psi-mi:a7bfv9_rat(display_long)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593197|mint:MINT-6168614|imex:IM-11281-18	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_031485.3|dip:DIP-32160N|ensembl:ENSMUSG00000002957(gene)|ensembl:ENSMUST00000003038(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030141"(secretory granule)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17427|rcsb pdb:1B9K|rcsb pdb:1KY6|rcsb pdb:1KY7|rcsb pdb:1KYD|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QTP|rcsb pdb:1QTS|rcsb pdb:1W80|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2VJ0|rcsb pdb:3HS8|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-6798695|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038|mint:MINT-6168618(identity)	mint:A7BFV9|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR003903(Ubiquitin interacting motif)|go:"GO:0005509"(calcium ion binding)|mint:MINT-6168621(identity)	-	-	-	figure legend:F6A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:KlOjm5d8qxxQkcuD2Hukoj8DLss10090	rogid:R3E+FrsPBjI+M4QkNZ8lboaInKw10116	intact-crc:701C45460D433506|rigid:q9r10ry+n6odZt7zt55KKPAsbC8	false	binding-associated region:701-938(MINT-6168628)|glutathione s tranferase tag:?-?(MINT-6168625)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CR95	uniprotkb:A7BFV9	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-6095043	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:a7bfv9_rat(display_long)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593256|mint:MINT-6168646|imex:IM-11281-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168656(identity)	mint:A7BFV9|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR003903(Ubiquitin interacting motif)|go:"GO:0005509"(calcium ion binding)|mint:MINT-6168658(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:F6A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:R3E+FrsPBjI+M4QkNZ8lboaInKw10116	intact-crc:B8610F5F408F244D|rigid:Zr1SYBK+4SHv20O56csf3hopR44	false	mutation disrupting interaction:21-21(MINT-6168675)|mutation disrupting interaction:102-102(MINT-6168677)|binding-associated region:1-178(MINT-6168668)|glutathione s tranferase tag:?-?(MINT-6168665)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CR95	uniprotkb:Q05140	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-1374805	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:ap180_rat(display_long)|uniprotkb:Snap91(gene name)|psi-mi:Snap91(display_short)|uniprotkb:Clathrin coat-associated protein AP180(gene name synonym)|uniprotkb:91 kDa synaptosomal-associated protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593256|mint:MINT-6168646|imex:IM-11281-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168656(identity)	rgd:69276|refseq:NP_113916.1|interpro:IPR011417(ANTH)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|mint:Q05140|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098894"(extrinsic component of presynaptic endocytic zone membrane)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1900275"(negative regulation of phospholipase C activity)|go:"GO:1904006"(negative regulation of phospholipase D activity)|go:"GO:1905445"(positive regulation of clathrin coat assembly)|go:"GO:2000331"(regulation of terminal button organization)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|reactome:R-RNO-8856825|reactome:R-RNO-8856828|go:"GO:0000149"(SNARE binding)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043679"(axon terminus)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048666"(neuron development)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051899"(membrane depolarization)|interpro:IPR030428|mint:MINT-6168657(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:F6A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:LXxIlR8jL+mLJ94McATz+sj4xF410116	intact-crc:B8610F5F408F244D|rigid:Zr1SYBK+4SHv20O56csf3hopR44	false	mutation disrupting interaction:21-21(MINT-6168675)|mutation disrupting interaction:102-102(MINT-6168677)|binding-associated region:1-178(MINT-6168668)|glutathione s tranferase tag:?-?(MINT-6168665)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q62910-1	uniprotkb:Q9CR95	intact:EBI-7593203|intact:MINT-128591|ensembl:ENSRNOP00000060346	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	psi-mi:q62910-1(display_long)|uniprotkb:Synj1(gene name)|psi-mi:Synj1(display_short)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1(gene name synonym)|uniprotkb:170 kDa(isoform synonym)	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593299|mint:MINT-6168680|imex:IM-11281-20	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1149123(isoform-parent)|ensembl:ENSRNOG00000002051(gene)|ensembl:ENSRNOT00000065535(transcript)|mint:MINT-6168691(identity)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168682(identity)	-	isoform-comment:A stop codon in position 1309 is suppressed due to alternative splicing|comment:mint	comment:mint|function:Involved in endocytosis	figure legend:F6A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:EJnYHctzzxfhvA7evwx+c2HKuIE10116	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	intact-crc:E2D9D43DDA7B8FA9|rigid:0WB7S/dH2GEQ+gJUtgEPkf1Hk+I	false	-	glutathione s tranferase tag:?-?(MINT-6168689)|mutation decreasing interaction:21-21(MINT-6168685)|binding-associated region:1-178(MINT-6168687)|mutation disrupting interaction:102-102(MINT-6168683)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9D1J1	uniprotkb:Q05140	intact:EBI-7592608|intact:MINT-4126596|uniprotkb:Q3U1M1|uniprotkb:Q9CV41|ensembl:ENSMUSP00000030760	intact:EBI-1374805	psi-mi:necp2_mouse(display_long)|uniprotkb:Necap2(gene name)|psi-mi:Necap2(display_short)|uniprotkb:NECAP endocytosis-associated protein 2(gene name synonym)	psi-mi:ap180_rat(display_long)|uniprotkb:Snap91(gene name)|psi-mi:Snap91(display_short)|uniprotkb:Clathrin coat-associated protein AP180(gene name synonym)|uniprotkb:91 kDa synaptosomal-associated protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593350|mint:MINT-6168697|imex:IM-11281-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079659.1|ensembl:ENSMUSG00000028923(gene)|ensembl:ENSMUST00000030760(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9D1J1|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-8856825|reactome:R-MMU-8856828|mint:MINT-6168699(identity)	rgd:69276|refseq:NP_113916.1|interpro:IPR011417(ANTH)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|mint:Q05140|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098894"(extrinsic component of presynaptic endocytic zone membrane)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1900275"(negative regulation of phospholipase C activity)|go:"GO:1904006"(negative regulation of phospholipase D activity)|go:"GO:1905445"(positive regulation of clathrin coat assembly)|go:"GO:2000331"(regulation of terminal button organization)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|reactome:R-RNO-8856825|reactome:R-RNO-8856828|go:"GO:0000149"(SNARE binding)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043679"(axon terminus)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048666"(neuron development)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051899"(membrane depolarization)|interpro:IPR030428|mint:MINT-6168709(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:F6A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:9hf6YTpQlYFB4HyGB+xkn72/8hI10090	rogid:LXxIlR8jL+mLJ94McATz+sj4xF410116	intact-crc:B39EA90B24A4E29B|rigid:mXmk6Mv0zpsAcuGajbQFvTsYwF8	false	mutation disrupting interaction:20-20(MINT-6168702)|binding-associated region:1-177(MINT-6168704)|mutation increasing interaction:41-41(MINT-6168749)|glutathione s tranferase tag:?-?(MINT-6168706)|mutation disrupting interaction:101-101(MINT-6168700)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:O88339	uniprotkb:Q9D1J1	intact:EBI-7066728|intact:MINT-101104	intact:EBI-7592608|intact:MINT-4126596|uniprotkb:Q3U1M1|uniprotkb:Q9CV41|ensembl:ENSMUSP00000030760	psi-mi:epn1_rat(display_long)|uniprotkb:Epn1(gene name)|psi-mi:Epn1(display_short)|uniprotkb:EPS-15-interacting protein 1(gene name synonym)	psi-mi:necp2_mouse(display_long)|uniprotkb:Necap2(gene name)|psi-mi:Necap2(display_short)|uniprotkb:NECAP endocytosis-associated protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593449|mint:MINT-6168722|imex:IM-11281-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:O88339|go:"GO:1905445"(positive regulation of clathrin coat assembly)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:1EDU|rcsb pdb:1EYH|rcsb pdb:1H0A|rcsb pdb:1KY6|reactome:R-RNO-182971|reactome:R-RNO-8856825|reactome:R-RNO-8856828|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0090148"(membrane fission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|rgd:619772|refseq:NP_476477.1|dip:DIP-40738N|mint:MINT-6168733(identity)	refseq:NP_079659.1|ensembl:ENSMUSG00000028923(gene)|ensembl:ENSMUST00000030760(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9D1J1|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-8856825|reactome:R-MMU-8856828|mint:MINT-6168724(identity)	-	comment:mint|function:"Binds to membranes enriched in phosphatidylinositol-4,5-biphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis"	comment:mint|function:Involved in endocytosis	figure legend:F6A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:HSxImXvS6/UJyI9kGWz36B0oxiM10116	rogid:9hf6YTpQlYFB4HyGB+xkn72/8hI10090	intact-crc:8A8993755936956F|rigid:ZSLYdGsmlkZFkzV5DfrrcplqOZ4	false	-	mutation disrupting interaction:101-101(MINT-6168731)|binding-associated region:1-177(MINT-6168729)|glutathione s tranferase tag:?-?(MINT-6168727)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q62910-1	uniprotkb:Q9D1J1	intact:EBI-7593203|intact:MINT-128591|ensembl:ENSRNOP00000060346	intact:EBI-7592608|intact:MINT-4126596|uniprotkb:Q3U1M1|uniprotkb:Q9CV41|ensembl:ENSMUSP00000030760	psi-mi:q62910-1(display_long)|uniprotkb:Synj1(gene name)|psi-mi:Synj1(display_short)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1(gene name synonym)|uniprotkb:170 kDa(isoform synonym)	psi-mi:necp2_mouse(display_long)|uniprotkb:Necap2(gene name)|psi-mi:Necap2(display_short)|uniprotkb:NECAP endocytosis-associated protein 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593405|mint:MINT-6168710|imex:IM-11281-22	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-1149123(isoform-parent)|ensembl:ENSRNOG00000002051(gene)|ensembl:ENSRNOT00000065535(transcript)|mint:MINT-6168721(identity)	refseq:NP_079659.1|ensembl:ENSMUSG00000028923(gene)|ensembl:ENSMUST00000030760(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9D1J1|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-8856825|reactome:R-MMU-8856828|mint:MINT-6168712(identity)	-	isoform-comment:A stop codon in position 1309 is suppressed due to alternative splicing|comment:mint	comment:mint|function:Involved in endocytosis	figure legend:F6A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:EJnYHctzzxfhvA7evwx+c2HKuIE10116	rogid:9hf6YTpQlYFB4HyGB+xkn72/8hI10090	intact-crc:0EFC26EFC1B6170F|rigid:bB50QMutZSDikNaE1jFgjLF3OII	false	-	binding-associated region:1-177(MINT-6168717)|glutathione s tranferase tag:?-?(MINT-6168715)|mutation decreasing interaction:20-20(MINT-6168713)|mutation disrupting interaction:101-101(MINT-6168719)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9CR95	uniprotkb:O60641	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-1105187|uniprotkb:Q5JX13|uniprotkb:Q68DL9|uniprotkb:Q6P9D3|uniprotkb:Q9NTY7|uniprotkb:A8K0L7|ensembl:ENSP00000358708|ensembl:ENSP00000400459|ensembl:ENSP00000428215|uniprotkb:E5RI02	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:ap180_human(display_long)|uniprotkb:SNAP91(gene name)|psi-mi:SNAP91(display_short)|uniprotkb:KIAA0656(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP180(gene name synonym)|uniprotkb:91 kDa synaptosomal-associated protein(gene name synonym)|uniprotkb:Phosphoprotein F1-20(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593496|mint:MINT-6168787|imex:IM-11281-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168794(identity)	refseq:NP_001243646.1|refseq:XP_011534567.1|refseq:XP_011534568.1|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015031"(protein transport)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098894"(extrinsic component of presynaptic endocytic zone membrane)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|interpro:IPR030428|mint:O60641|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0006900"(vesicle budding from membrane)|ensembl:ENSG00000065609(gene)|ensembl:ENST00000369694(transcript)|ensembl:ENST00000439399(transcript)|ensembl:ENST00000521743(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005905"(clathrin-coated pit)|refseq:NP_001229721.1|refseq:NP_001229722.1|refseq:NP_001229723.1|refseq:NP_055656.1|refseq:NP_001243647.1|refseq:XP_006715678.1|refseq:XP_005248827.1|mint:MINT-6168789(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:SF2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:aDVpucWv2pzqFDsgf9u6uQWtz6U9606	intact-crc:B14DAB5BC87F424C|rigid:SL3ENi9HARlSKa7cSkonc0QtQ34	false	his tag:?-?(MINT-6168795)	binding-associated region:558-573(MINT-6168790)|glutathione s tranferase tag:?-?(MINT-6168792)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9D1J1	uniprotkb:A7BFV9	intact:EBI-7592608|intact:MINT-4126596|uniprotkb:Q3U1M1|uniprotkb:Q9CV41|ensembl:ENSMUSP00000030760	intact:EBI-6095043	psi-mi:necp2_mouse(display_long)|uniprotkb:Necap2(gene name)|psi-mi:Necap2(display_short)|uniprotkb:NECAP endocytosis-associated protein 2(gene name synonym)	psi-mi:a7bfv9_rat(display_long)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593470|mint:MINT-6168734|imex:IM-11281-24	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_079659.1|ensembl:ENSMUSG00000028923(gene)|ensembl:ENSMUST00000030760(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9D1J1|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-8856825|reactome:R-MMU-8856828|mint:MINT-6168736(identity)	mint:A7BFV9|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR003903(Ubiquitin interacting motif)|go:"GO:0005509"(calcium ion binding)|mint:MINT-6168746(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:F6A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:9hf6YTpQlYFB4HyGB+xkn72/8hI10090	rogid:R3E+FrsPBjI+M4QkNZ8lboaInKw10116	intact-crc:C503B852A28102F1|rigid:ADgxJqvEowjjhjeYtIEXG7/37Tw	false	binding-associated region:1-178(MINT-6168739)|mutation disrupting interaction:20-20(MINT-6168741)|mutation disrupting interaction:101-101(MINT-6168743)|glutathione s tranferase tag:?-?(MINT-6168737)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P98078	uniprotkb:Q9CR95	intact:EBI-1391846|uniprotkb:Q3U3K1|uniprotkb:Q91W56|uniprotkb:Q923E1	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	psi-mi:dab2_mouse(display_long)|uniprotkb:Mitogen-responsive phosphoprotein(gene name synonym)|uniprotkb:Dab2(gene name)|psi-mi:Dab2(display_short)|uniprotkb:Doc2(gene name synonym)|uniprotkb:Adaptor molecule disabled-2(gene name synonym)|uniprotkb:Differentially expressed in ovarian carcinoma 2(gene name synonym)	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593629|mint:MINT-6168807|imex:IM-11281-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008702.1|refseq:NP_001032994.1|refseq:NP_075607.2|mint:P98078|refseq:XP_011243626.1|refseq:XP_017171913.1|dip:DIP-39422N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005178"(integrin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007588"(excretion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032349"(positive regulation of aldosterone biosynthetic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035026"(leading edge cell differentiation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000298"(regulation of Rho-dependent protein serine/threonine kinase activity)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|go:"GO:2000860"(positive regulation of aldosterone secretion)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:1M7E|rcsb pdb:1P3R|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-8856825|reactome:R-MMU-8856828|mint:MINT-6168809(identity)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168814(identity)	-	-	comment:mint|function:Involved in endocytosis	figure legend:SF2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:CCerpRI40+Lf1+uFkDr1xJwM5Wg10090	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	intact-crc:8C57C45314957C74|rigid:HhpA1Z9gYbeFcH1eGaGDOtsuoyA	false	binding-associated region:475-489(MINT-6168810)|glutathione s tranferase tag:?-?(MINT-6168812)	his tag:?-?(MINT-6168815)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9CR95	uniprotkb:O60641	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-1105187|uniprotkb:Q5JX13|uniprotkb:Q68DL9|uniprotkb:Q6P9D3|uniprotkb:Q9NTY7|uniprotkb:A8K0L7|ensembl:ENSP00000358708|ensembl:ENSP00000400459|ensembl:ENSP00000428215|uniprotkb:E5RI02	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:ap180_human(display_long)|uniprotkb:SNAP91(gene name)|psi-mi:SNAP91(display_short)|uniprotkb:KIAA0656(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP180(gene name synonym)|uniprotkb:91 kDa synaptosomal-associated protein(gene name synonym)|uniprotkb:Phosphoprotein F1-20(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593546|mint:MINT-6168797|imex:IM-11281-26	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168804(identity)	refseq:NP_001243646.1|refseq:XP_011534567.1|refseq:XP_011534568.1|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015031"(protein transport)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098894"(extrinsic component of presynaptic endocytic zone membrane)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|interpro:IPR030428|mint:O60641|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0006900"(vesicle budding from membrane)|ensembl:ENSG00000065609(gene)|ensembl:ENST00000369694(transcript)|ensembl:ENST00000439399(transcript)|ensembl:ENST00000521743(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005905"(clathrin-coated pit)|refseq:NP_001229721.1|refseq:NP_001229722.1|refseq:NP_001229723.1|refseq:NP_055656.1|refseq:NP_001243647.1|refseq:XP_006715678.1|refseq:XP_005248827.1|mint:MINT-6168799(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:SF2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:aDVpucWv2pzqFDsgf9u6uQWtz6U9606	intact-crc:D020D2C27E1ECB2F|rigid:SL3ENi9HARlSKa7cSkonc0QtQ34	false	his tag:?-?(MINT-6168805)	glutathione s tranferase tag:?-?(MINT-6168800)|binding-associated region:637-651(MINT-6168802)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P98078	uniprotkb:Q9CR95	intact:EBI-1391846|uniprotkb:Q3U3K1|uniprotkb:Q91W56|uniprotkb:Q923E1	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	psi-mi:dab2_mouse(display_long)|uniprotkb:Mitogen-responsive phosphoprotein(gene name synonym)|uniprotkb:Dab2(gene name)|psi-mi:Dab2(display_short)|uniprotkb:Doc2(gene name synonym)|uniprotkb:Adaptor molecule disabled-2(gene name synonym)|uniprotkb:Differentially expressed in ovarian carcinoma 2(gene name synonym)	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593676|mint:MINT-6168817|imex:IM-11281-28	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001008702.1|refseq:NP_001032994.1|refseq:NP_075607.2|mint:P98078|refseq:XP_011243626.1|refseq:XP_017171913.1|dip:DIP-39422N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001650"(fibrillar center)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005178"(integrin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007588"(excretion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015031"(protein transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032349"(positive regulation of aldosterone biosynthetic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035026"(leading edge cell differentiation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|go:"GO:2000298"(regulation of Rho-dependent protein serine/threonine kinase activity)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|go:"GO:2000860"(positive regulation of aldosterone secretion)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:1M7E|rcsb pdb:1P3R|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-8856825|reactome:R-MMU-8856828|mint:MINT-6168819(identity)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168824(identity)	-	-	comment:mint|function:Involved in endocytosis	figure legend:SF2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:CCerpRI40+Lf1+uFkDr1xJwM5Wg10090	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	intact-crc:992156A4E0555ED7|rigid:HhpA1Z9gYbeFcH1eGaGDOtsuoyA	false	glutathione s tranferase tag:?-?(MINT-6168820)|binding-associated region:?-?(MINT-6168822)	his tag:?-?(MINT-6168825)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q9CR95	uniprotkb:P49418	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-7121510|ensembl:ENSP00000348602|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593747|mint:MINT-6168827|imex:IM-11281-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168834(identity)	ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|mint:P49418|rcsb pdb:1KY7|rcsb pdb:1UTC|rcsb pdb:3SOG|rcsb pdb:4ATM|rcsb pdb:5M5S|rcsb pdb:5M61|reactome:R-HSA-8856828|refseq:NP_001626.1|refseq:NP_647477.1|dip:DIP-40729N|mint:MINT-6168829(identity)	-	comment:mint|function:Involved in endocytosis	function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms	figure legend:SF2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606	intact-crc:5172886BCC1C4A47|rigid:wvizuqsoMhggEMIP556aF4QBsxc	false	his tag:?-?(MINT-6168835)	glutathione s tranferase tag:?-?(MINT-6168832)|binding-associated region:319-333(MINT-6168830)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9CR95	uniprotkb:O00291	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-473886|uniprotkb:O00328|uniprotkb:Q8TDL4|uniprotkb:Q2TB58|uniprotkb:V5LU97|uniprotkb:B4E3I7|uniprotkb:E7ES17|ensembl:ENSP00000336747	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:hip1_human(display_long)|uniprotkb:HIP1(gene name)|psi-mi:HIP1(display_short)|uniprotkb:Huntingtin-interacting protein I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593782|mint:MINT-6168837|imex:IM-11281-30	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168844(identity)	go:"GO:0051015"(actin filament binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099637"(neurotransmitter receptor transport)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR002558(I/LWEQ)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030224|interpro:IPR030554|interpro:IPR032422|interpro:IPR035964|mint:O00291|rcsb pdb:2NO2|rcsb pdb:2QA7|rcsb pdb:3I00|reactome:R-HSA-8856828|refseq:NP_005329.3|refseq:NP_001230127.1|refseq:XP_005250361.1|refseq:XP_011514418.1|ensembl:ENSG00000127946(gene)|ensembl:ENST00000336926(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0016020"(membrane)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030276"(clathrin binding)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0050821"(protein stabilization)|dip:DIP-17041N|mint:MINT-6168839(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:SF2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:tv7gJyUeUPo98+42G8L980EnE/c9606	intact-crc:EC6A3BCA2B8C31A5|rigid:6jjFDjdboU4STPI8GwPiXaRacUw	false	his tag:?-?(MINT-6168845)	binding-associated region:338-350(MINT-6168842)|glutathione s tranferase tag:?-?(MINT-6168840)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9CR95	uniprotkb:O00291	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-473886|uniprotkb:O00328|uniprotkb:Q8TDL4|uniprotkb:Q2TB58|uniprotkb:V5LU97|uniprotkb:B4E3I7|uniprotkb:E7ES17|ensembl:ENSP00000336747	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:hip1_human(display_long)|uniprotkb:HIP1(gene name)|psi-mi:HIP1(display_short)|uniprotkb:Huntingtin-interacting protein I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593838|mint:MINT-6168847|imex:IM-11281-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168854(identity)	go:"GO:0051015"(actin filament binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099637"(neurotransmitter receptor transport)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR002558(I/LWEQ)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030224|interpro:IPR030554|interpro:IPR032422|interpro:IPR035964|mint:O00291|rcsb pdb:2NO2|rcsb pdb:2QA7|rcsb pdb:3I00|reactome:R-HSA-8856828|refseq:NP_005329.3|refseq:NP_001230127.1|refseq:XP_005250361.1|refseq:XP_011514418.1|ensembl:ENSG00000127946(gene)|ensembl:ENST00000336926(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0016020"(membrane)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030276"(clathrin binding)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0050821"(protein stabilization)|dip:DIP-17041N|mint:MINT-6168849(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:SF2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:tv7gJyUeUPo98+42G8L980EnE/c9606	intact-crc:8FEE588AE44D92EF|rigid:6jjFDjdboU4STPI8GwPiXaRacUw	false	his tag:?-?(MINT-6168855)	glutathione s tranferase tag:?-?(MINT-6168852)|binding-associated region:344-354(MINT-6168850)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9CR95	uniprotkb:O00291	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-473886|uniprotkb:O00328|uniprotkb:Q8TDL4|uniprotkb:Q2TB58|uniprotkb:V5LU97|uniprotkb:B4E3I7|uniprotkb:E7ES17|ensembl:ENSP00000336747	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:hip1_human(display_long)|uniprotkb:HIP1(gene name)|psi-mi:HIP1(display_short)|uniprotkb:Huntingtin-interacting protein I(gene name synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593876|mint:MINT-6168857|imex:IM-11281-32	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168864(identity)	go:"GO:0051015"(actin filament binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099637"(neurotransmitter receptor transport)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR002558(I/LWEQ)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030224|interpro:IPR030554|interpro:IPR032422|interpro:IPR035964|mint:O00291|rcsb pdb:2NO2|rcsb pdb:2QA7|rcsb pdb:3I00|reactome:R-HSA-8856828|refseq:NP_005329.3|refseq:NP_001230127.1|refseq:XP_005250361.1|refseq:XP_011514418.1|ensembl:ENSG00000127946(gene)|ensembl:ENST00000336926(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007015"(actin filament organization)|go:"GO:0016020"(membrane)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030276"(clathrin binding)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0050821"(protein stabilization)|dip:DIP-17041N|mint:MINT-6168859(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:SF2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:tv7gJyUeUPo98+42G8L980EnE/c9606	intact-crc:B9CC4B3D0C515AC8|rigid:6jjFDjdboU4STPI8GwPiXaRacUw	false	his tag:?-?(MINT-6168865)	binding-associated region:348-359(MINT-6168862)|glutathione s tranferase tag:?-?(MINT-6168860)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9CR95	uniprotkb:O43426-1	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-7237240|intact:MINT-109231|ensembl:ENSP00000501426	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:o43426-1(display_long)|uniprotkb:SYNJ1(gene name)|psi-mi:SYNJ1(display_short)|uniprotkb:KIAA0910(gene name synonym)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1(gene name synonym)|uniprotkb:Synaptojanin-170(isoform synonym)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593929|mint:MINT-6168867|imex:IM-11281-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168874(identity)	intact:EBI-2821539(isoform-parent)|ensembl:ENSG00000159082(gene)|ensembl:ENST00000674308(transcript)|mint:MINT-6168869(identity)	-	comment:mint|function:Involved in endocytosis	comment:mint	figure legend:SF2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:RA73eMbCn6F7MD0ItxF/V7QbjqM9606	intact-crc:AB619355F7901DAC|rigid:WSvBLM54o5s2mnNKyHQ+7LWGnhU	false	his tag:?-?(MINT-6168875)	glutathione s tranferase tag:?-?(MINT-6168872)|binding-associated region:1456-1470(MINT-6168870)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9CR95	uniprotkb:Q13492	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-2803688|uniprotkb:Q86XZ9|uniprotkb:O60700|uniprotkb:Q6GMQ6|intact:EBI-28967113|ensembl:ENSP00000377015|uniprotkb:B4DTM3|uniprotkb:E9PN05|uniprotkb:F8VPG7|uniprotkb:Q4LE54	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:pical_human(display_long)|uniprotkb:CALM(gene name synonym)|uniprotkb:Clathrin assembly lymphoid myeloid leukemia protein(gene name synonym)|uniprotkb:PICALM(gene name)|psi-mi:PICALM(display_short)	psi-mi:"MI:0096"(pull down)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7593981|mint:MINT-6168877|imex:IM-11281-34	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168884(identity)	ensembl:ENST00000356360|ensembl:ENSP00000348718|ensembl:ENSP00000377015|ensembl:ENST00000526033|ensembl:ENSP00000433846|ensembl:ENST00000528398|ensembl:ENSP00000434884|ensembl:ENST00000532317|ensembl:ENSP00000436958|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007409"(axonogenesis)|go:"GO:0007611"(learning or memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0031982"(vesicle)|go:"GO:0005634"(nucleus)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1905224"(clathrin-coated pit assembly)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|interpro:IPR030412|mint:Q13492|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9696264|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048156"(tau protein binding)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0032050"(clathrin heavy chain binding)|ensembl:ENSG00000073921(gene)|ensembl:ENST00000393346(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070381"(endosome to plasma membrane transport vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0097753"(membrane bending)|go:"GO:0098894"(extrinsic component of presynaptic endocytic zone membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902959"(regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902963"(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:0055072"(iron ion homeostasis)|refseq:NP_001008660.1|refseq:NP_001193875.1|refseq:NP_001193876.1|refseq:NP_009097.2|refseq:XP_005274388.1|mint:MINT-6168879(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:SF2|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:UIZhYyYqmBCyN4xwPCl9PeCdK8Q9606	intact-crc:3C8B919C00EBBD6C|rigid:oMdsuymGiKmeX+LQrlZmY7z6SC4	false	his tag:?-?(MINT-6168885)	glutathione s tranferase tag:?-?(MINT-6168880)|binding-associated region:484-498(MINT-6168882)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P69682	uniprotkb:O08838	intact:EBI-7592718|intact:MINT-5260811|uniprotkb:Q4QR67|ensembl:ENSRNOP00000013272	intact:EBI-80080	psi-mi:necp1_rat(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:amph_rat(display_long)|uniprotkb:Amph(gene name)|psi-mi:Amph(display_short)|uniprotkb:Amph1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594011|mint:MINT-5261856|imex:IM-11281-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001025090.1|rgd:1306053|ensembl:ENSRNOG00000009236(gene)|ensembl:ENSRNOT00000013272(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:P69682|reactome:R-RNO-432722|reactome:R-RNO-8856825|reactome:R-RNO-8856828|dip:DIP-44064N|mint:MINT-5261858(identity)	go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|rcsb pdb:2VJ0|rcsb pdb:5M5T|reactome:R-RNO-8856828|rgd:620274|refseq:NP_071553.1|mint:O08838|dip:DIP-30977N|mint:MINT-5261863(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:f2c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2007/11/20	2014/10/16	rogid:KwuJp3lG7BL4q4Fzy7YtThmdCso10116	rogid:wTANhsy4BxCZYbSIhwlrr+m9Tt810116	intact-crc:4F926674EDBAF2A5|rigid:j/QQ0TW8NngU/7k3Ny7iFUarSJg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P69682	uniprotkb:O08839	intact:EBI-7592718|intact:MINT-5260811|uniprotkb:Q4QR67|ensembl:ENSRNOP00000013272	intact:EBI-80095	psi-mi:necp1_rat(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:bin1_rat(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:Amph2(gene name synonym)|uniprotkb:Amphl(gene name synonym)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594011|mint:MINT-5261856|imex:IM-11281-4	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001025090.1|rgd:1306053|ensembl:ENSRNOG00000009236(gene)|ensembl:ENSRNOT00000013272(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:P69682|reactome:R-RNO-432722|reactome:R-RNO-8856825|reactome:R-RNO-8856828|dip:DIP-44064N|mint:MINT-5261858(identity)	go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005768"(endosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0043196"(varicosity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060987"(lipid tube)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|rcsb pdb:1BB9|reactome:R-RNO-8856828|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|rgd:621786|refseq:NP_446411.1|mint:O08839|dip:DIP-30979N|mint:MINT-5261912(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:f2c|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain)|taxid:10116(Rattus norvegicus brain)	-	2007/11/20	2014/10/16	rogid:KwuJp3lG7BL4q4Fzy7YtThmdCso10116	rogid:xqcXQWo+FXHjCGGI0Q9agaz9LMk10116	intact-crc:4F926674EDBAF2A5|rigid:j/QQ0TW8NngU/7k3Ny7iFUarSJg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CR95	uniprotkb:P49418	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-7121510|ensembl:ENSP00000348602|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)	psi-mi:"MI:0405"(competition binding)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594051|mint:MINT-6167796|imex:IM-11281-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6167798(identity)	ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|mint:P49418|rcsb pdb:1KY7|rcsb pdb:1UTC|rcsb pdb:3SOG|rcsb pdb:4ATM|rcsb pdb:5M5S|rcsb pdb:5M61|reactome:R-HSA-8856828|refseq:NP_001626.1|refseq:NP_647477.1|dip:DIP-40729N|mint:MINT-6167800(identity)	-	comment:mint|function:Involved in endocytosis	function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms	figure legend:F3E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606	intact-crc:3CC585F508DCC63B|rigid:Uazrmz8wmG+GD3c/Cq1QPlXf6NQ	false	binding-associated region:1-133(MINT-6168025)|glutathione s tranferase tag:?-?(MINT-6168022)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CR95	uniprotkb:O08839	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-80095	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:bin1_rat(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:Amph2(gene name synonym)|uniprotkb:Amphl(gene name synonym)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:"MI:0405"(competition binding)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594051|mint:MINT-6167796|imex:IM-11281-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6167798(identity)	go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005768"(endosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0043196"(varicosity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060987"(lipid tube)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|rcsb pdb:1BB9|reactome:R-RNO-8856828|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|rgd:621786|refseq:NP_446411.1|mint:O08839|dip:DIP-30979N|mint:MINT-6167799(identity)	-	comment:mint|function:Involved in endocytosis	-	figure legend:F3E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:xqcXQWo+FXHjCGGI0Q9agaz9LMk10116	intact-crc:3CC585F508DCC63B|rigid:Uazrmz8wmG+GD3c/Cq1QPlXf6NQ	false	binding-associated region:1-133(MINT-6168025)|glutathione s tranferase tag:?-?(MINT-6168022)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9CR95	uniprotkb:P49418	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-7121510|ensembl:ENSP00000348602|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594103|mint:MINT-6168042|imex:IM-11281-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168044(identity)	ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|mint:P49418|rcsb pdb:1KY7|rcsb pdb:1UTC|rcsb pdb:3SOG|rcsb pdb:4ATM|rcsb pdb:5M5S|rcsb pdb:5M61|reactome:R-HSA-8856828|refseq:NP_001626.1|refseq:NP_647477.1|dip:DIP-40729N|mint:MINT-6168049(identity)	-	comment:mint|function:Involved in endocytosis	function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms	figure legend:F4A F4B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606	intact-crc:268A5F6EA2F3D781|rigid:wvizuqsoMhggEMIP556aF4QBsxc	false	-	binding-associated region:291-329(MINT-6168084)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9CR95	uniprotkb:P49418	intact:EBI-7592476|uniprotkb:Q3TH13|uniprotkb:Q78JW3|uniprotkb:Q8C4P1|intact:MINT-4125077|ensembl:ENSMUSP00000032477	intact:EBI-7121510|ensembl:ENSP00000348602|uniprotkb:Q75MK5|uniprotkb:Q75MM3|uniprotkb:A4D1X9|intact:MINT-109264|uniprotkb:O43538|uniprotkb:A4D1X8|uniprotkb:Q75MJ8|uniprotkb:Q8N4G0	psi-mi:necp1_mouse(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:amph_human(display_long)|uniprotkb:AMPH(gene name)|psi-mi:AMPH(display_short)|uniprotkb:AMPH1(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Ritter et al. (2007)	pubmed:17762867|imex:IM-11281|mint:MINT-5223036	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7594117|mint:MINT-6168089|imex:IM-11281-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_080543.2|ensembl:ENSMUSG00000030327(gene)|ensembl:ENSMUST00000032477(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:Q9CR95|rcsb pdb:1TQZ|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|dip:DIP-44062N|mint:MINT-6168094(identity)	ensembl:ENSG00000078053(gene)|ensembl:ENST00000356264(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031256"(leading edge membrane)|go:"GO:0048488"(synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|mint:P49418|rcsb pdb:1KY7|rcsb pdb:1UTC|rcsb pdb:3SOG|rcsb pdb:4ATM|rcsb pdb:5M5S|rcsb pdb:5M61|reactome:R-HSA-8856828|refseq:NP_001626.1|refseq:NP_647477.1|dip:DIP-40729N|mint:MINT-6168091(identity)	-	comment:mint|function:Involved in endocytosis	function:May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton|comment:mint|comment:homomint|function:Antibodies against AMPH are detected in patients with stiff-man syndrome, a rare disease of the central nervous system characterized by progressive rigidity of the body musculature with superimposed painful spasms	figure legend:F5A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/20	2014/10/16	rogid:K6TGVkeAIMEFvb9sM1SS5bSdvjU10090	rogid:vrgVrVoYr45cUe4X6L/zBAE1RtU9606	intact-crc:BF676F9F5C20C98C|rigid:wvizuqsoMhggEMIP556aF4QBsxc	false	-	binding-associated region:291-445(MINT-6168092)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)