#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q8VD04	uniprotkb:A3KBF5	intact:EBI-7585099|uniprotkb:A2AEW7|uniprotkb:O35693|uniprotkb:Q69ZP9|uniprotkb:Q3T9C3|intact:MINT-4609304|ensembl:ENSMUSP00000068789	intact:EBI-7585074|intact:MINT-5209596	psi-mi:grap1_mouse(display_long)|uniprotkb:Gripap1(gene name)|psi-mi:Gripap1(display_short)|uniprotkb:DXImx47e(gene name synonym)|uniprotkb:Kiaa1167(gene name synonym)|uniprotkb:HCMV-interacting protein(gene name synonym)	psi-mi:a3kbf5_mouse(display_long)|uniprotkb:Mapk8(gene name)|psi-mi:Mapk8(display_short)|uniprotkb:jnk1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ye et al. (2007)	pubmed:17761173|imex:IM-11469|mint:MINT-5220148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7585117|mint:MINT-5209607|imex:IM-11469-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_997553.1|ensembl:ENSMUSG00000031153(gene)|ensembl:ENSMUST00000065932(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098998"(extrinsic component of postsynaptic early endosome membrane)|go:"GO:0099152"(regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0099158"(regulation of recycling endosome localization within postsynapse)|go:"GO:1905244"(regulation of modification of synaptic structure)|interpro:IPR026204|mint:Q8VD04|mint:MINT-5209608(identity)	mint:A3KBF5|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|mint:MINT-5209609(identity)	-	comment:mint	comment:mint	figure legend:F2A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/10/23	2014/10/16	rogid:if5RPMbiuuu/rqXtkhbJg8X0Z2w10090	rogid:KpAkFAQvmUt+CUN9mFgvEdDyuUM10090	intact-crc:0AE4719BD99E9250|rigid:e4k/oqaRgj8cis17J4nF0twLAmI	false	myc tag:?-?(MINT-5209613)	ha tag:?-?(MINT-5209620)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8VD04	uniprotkb:Q62925	intact:EBI-7585099|uniprotkb:A2AEW7|uniprotkb:O35693|uniprotkb:Q69ZP9|uniprotkb:Q3T9C3|intact:MINT-4609304|ensembl:ENSMUSP00000068789	intact:EBI-636664	psi-mi:grap1_mouse(display_long)|uniprotkb:Gripap1(gene name)|psi-mi:Gripap1(display_short)|uniprotkb:DXImx47e(gene name synonym)|uniprotkb:Kiaa1167(gene name synonym)|uniprotkb:HCMV-interacting protein(gene name synonym)	psi-mi:m3k1_rat(display_long)|uniprotkb:MAPK/ERK kinase kinase 1(gene name synonym)|uniprotkb:Map3k1(gene name)|psi-mi:Map3k1(display_short)|uniprotkb:Mekk(gene name synonym)|uniprotkb:Mekk1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Ye et al. (2007)	pubmed:17761173|imex:IM-11469|mint:MINT-5220148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7585153|mint:MINT-5209624|imex:IM-11469-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_997553.1|ensembl:ENSMUSG00000031153(gene)|ensembl:ENSMUST00000065932(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098998"(extrinsic component of postsynaptic early endosome membrane)|go:"GO:0099152"(regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0099158"(regulation of recycling endosome localization within postsynapse)|go:"GO:1905244"(regulation of modification of synaptic structure)|interpro:IPR026204|mint:Q8VD04|mint:MINT-5209625(identity)	rgd:620966|refseq:NP_446339.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR007527(Zinc finger, SWIM-type)|go:"GO:0000165"(MAPK cascade)|interpro:IPR016024(Armadillo-type fold)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007254"(JNK cascade)|go:"GO:0007256"(obsolete activation of JNKK activity)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0042060"(wound healing)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|reactome:R-RNO-166058|reactome:R-RNO-2871796|reactome:R-RNO-975138|reactome:R-RNO-975871|interpro:IPR011989(Armadillo-like helical)|mint:Q62925|mint:MINT-5209629(identity)	-	comment:mint	-	figure legend:F2B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/10/23	2014/10/16	rogid:if5RPMbiuuu/rqXtkhbJg8X0Z2w10090	rogid:EwhjYjowkZIAt4UyPcZBUtf9uak10116	intact-crc:4C8F20AA7E469A3E|rigid:Bh7AqkQqCiUmzLH8E2BUbeZoFNQ	false	myc tag:?-?(MINT-5209626)	ha tag:?-?(MINT-5209630)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q8VD04	uniprotkb:P53349	intact:EBI-7585099|uniprotkb:A2AEW7|uniprotkb:O35693|uniprotkb:Q69ZP9|uniprotkb:Q3T9C3|intact:MINT-4609304|ensembl:ENSMUSP00000068789	intact:EBI-447913|uniprotkb:Q60831|uniprotkb:Q9R0U3|uniprotkb:Q9R256	psi-mi:grap1_mouse(display_long)|uniprotkb:Gripap1(gene name)|psi-mi:Gripap1(display_short)|uniprotkb:DXImx47e(gene name synonym)|uniprotkb:Kiaa1167(gene name synonym)|uniprotkb:HCMV-interacting protein(gene name synonym)	psi-mi:m3k1_mouse(display_long)|uniprotkb:MAPK/ERK kinase kinase 1(gene name synonym)|uniprotkb:Map3k1(gene name)|psi-mi:Map3k1(display_short)|uniprotkb:Mekk(gene name synonym)|uniprotkb:Mekk1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ye et al. (2007)	pubmed:17761173|imex:IM-11469|mint:MINT-5220148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7585245|mint:MINT-5209635|imex:IM-11469-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_997553.1|ensembl:ENSMUSG00000031153(gene)|ensembl:ENSMUST00000065932(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098998"(extrinsic component of postsynaptic early endosome membrane)|go:"GO:0099152"(regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0099158"(regulation of recycling endosome localization within postsynapse)|go:"GO:1905244"(regulation of modification of synaptic structure)|interpro:IPR026204|mint:Q8VD04|mint:MINT-5209636(identity)	go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007254"(JNK cascade)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008432"(JUN kinase binding)|dip:DIP-32487N|mint:P53349|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042060"(wound healing)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR007527(Zinc finger, SWIM-type)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|reactome:R-MMU-166058|reactome:R-MMU-2871796|reactome:R-MMU-975138|reactome:R-MMU-975871|interpro:IPR000719(Protein kinase, core)|mint:MINT-5209640(identity)	-	comment:mint	-	figure legend:F2C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-neuron)|taxid:10090(Mus musculus neuronal cell)	-	2007/10/23	2014/10/16	rogid:if5RPMbiuuu/rqXtkhbJg8X0Z2w10090	rogid:DR/c3qeWhJ76oKsNMEVhcUPmpXE10090	intact-crc:E0CEFCBE8ED0B2FA|rigid:1FmxssotdftAq1m1vkWSK70Ux8Q	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:A3KBF5	uniprotkb:Q8VD04	intact:EBI-7585074|intact:MINT-5209596	intact:EBI-7585099|uniprotkb:A2AEW7|uniprotkb:O35693|uniprotkb:Q69ZP9|uniprotkb:Q3T9C3|intact:MINT-4609304|ensembl:ENSMUSP00000068789	psi-mi:a3kbf5_mouse(display_long)|uniprotkb:Mapk8(gene name)|psi-mi:Mapk8(display_short)|uniprotkb:jnk1(gene name synonym)	psi-mi:grap1_mouse(display_long)|uniprotkb:Gripap1(gene name)|psi-mi:Gripap1(display_short)|uniprotkb:DXImx47e(gene name synonym)|uniprotkb:Kiaa1167(gene name synonym)|uniprotkb:HCMV-interacting protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Ye et al. (2007)	pubmed:17761173|imex:IM-11469|mint:MINT-5220148	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7585256|mint:MINT-5209670|imex:IM-11469-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:A3KBF5|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008351(JNK MAP kinase)|interpro:IPR011009(Protein kinase-like)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|mint:MINT-5209673(identity)	refseq:NP_997553.1|ensembl:ENSMUSG00000031153(gene)|ensembl:ENSMUST00000065932(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0098837"(postsynaptic recycling endosome)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098998"(extrinsic component of postsynaptic early endosome membrane)|go:"GO:0099152"(regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0099158"(regulation of recycling endosome localization within postsynapse)|go:"GO:1905244"(regulation of modification of synaptic structure)|interpro:IPR026204|mint:Q8VD04|mint:MINT-5209671(identity)	-	comment:mint	comment:mint	figure legend:F2C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-neuron)|taxid:10090(Mus musculus neuronal cell)	-	2007/10/23	2014/10/16	rogid:KpAkFAQvmUt+CUN9mFgvEdDyuUM10090	rogid:if5RPMbiuuu/rqXtkhbJg8X0Z2w10090	intact-crc:62FB374CA6F91B73|rigid:e4k/oqaRgj8cis17J4nF0twLAmI	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)