#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q15119 uniprotkb:O08852 intact:EBI-726271|uniprotkb:B3KNW0|uniprotkb:Q6P515|uniprotkb:Q9BS05|uniprotkb:A8K3A7|ensembl:ENSP00000420927 intact:EBI-6666305|ensembl:ENSMUSP00000049296|uniprotkb:E9QJR6 psi-mi:pdk2_human(display_long)|uniprotkb:Pyruvate dehydrogenase kinase isoform 2(gene name synonym)|uniprotkb:PDK2(gene name)|psi-mi:PDK2(display_short)|uniprotkb:PDHK2(gene name synonym) psi-mi:pkd1_mouse(display_long)|uniprotkb:Pkd1(gene name)|psi-mi:Pkd1(display_short)|uniprotkb:Autosomal dominant polycystic kidney disease 1 protein homolog(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Eiseler et al. (2007) pubmed:17707375|imex:IM-10904|mint:MINT-5222632 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7565229|mint:MINT-5222647|imex:IM-10904-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186828.1|refseq:NP_002602.2|refseq:NP_001186827.1|rcsb pdb:6LIO|rcsb pdb:6TMP|rcsb pdb:6TMQ|rcsb pdb:6TMZ|rcsb pdb:6TN0|rcsb pdb:6TN2|reactome:R-HSA-204174|reactome:R-HSA-5362517|ensembl:ENSG00000005882(gene)|ensembl:ENST00000503176(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004740"("pyruvate dehydrogenase (acetyl-transferring) kinase activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006885"(regulation of pH)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010510"(regulation of acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0010565"(regulation of cellular ketone metabolic process)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR018955|interpro:IPR036784|interpro:IPR036890|interpro:IPR039028|mint:Q15119|rcsb pdb:2BTZ|rcsb pdb:2BU2|rcsb pdb:2BU5|rcsb pdb:2BU6|rcsb pdb:2BU7|rcsb pdb:2BU8|rcsb pdb:4MP2|rcsb pdb:4MP7|rcsb pdb:4MPC|rcsb pdb:4MPE|rcsb pdb:4MPN|rcsb pdb:4V25|rcsb pdb:4V26|rcsb pdb:5J6A|rcsb pdb:5J71|rcsb pdb:5M4K|rcsb pdb:5M4M|rcsb pdb:5M4N|rcsb pdb:5M4P|rcsb pdb:6LIL|rcsb pdb:6LIN|mint:MINT-5222650(identity) ensembl:ENSMUSG00000032855(gene)|ensembl:ENSMUST00000035565(transcript)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002133"(polycystin complex)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007507"(heart development)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021915"(neural tube development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031514"(motile cilium)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034703"(cation channel complex)|go:"GO:0034704"(calcium channel complex)|go:"GO:0036303"(lymph vessel morphogenesis)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048806"(genitalia development)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0072177"(mesonephric duct development)|go:"GO:0072205"(metanephric collecting duct development)|go:"GO:0072218"(metanephric ascending thin limb development)|go:"GO:0072237"(metanephric proximal tubule development)|go:"GO:0072287"(metanephric distal tubule morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0198738"(cell-cell signaling by wnt)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000203(GPS)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000434(Polycystic kidney disease type 1 protein)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001304(C-type lectin)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002859(PKD/REJ-like protein)|interpro:IPR002889(Carbohydrate-binding WSC)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR006228(Polycystin cation channel)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014010(Egg jelly receptor, REJ-like)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR022409|interpro:IPR032675|interpro:IPR035986|interpro:IPR036392|interpro:IPR042060|mint:O08852|interpro:IPR000601(PKD)|refseq:NP_038658.2|dip:DIP-44233N|mint:MINT-5222648(identity) - - - figure legend:F2A F2C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/15 2014/10/16 rogid:mGS3AxBLzr8a/x1q6z7RkS99WkQ9606 rogid:GuuAhfakEvak5k2Zry2YxCjrQVk10090 intact-crc:FFFCAC5AF5D81DCB|rigid:LQu2SsC6rPOt1v9BkK3NUmybcfI false - mutation decreasing interaction:?-?(MINT-5222660) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q15119 uniprotkb:Q14247 intact:EBI-726271|uniprotkb:B3KNW0|uniprotkb:Q6P515|uniprotkb:Q9BS05|uniprotkb:A8K3A7|ensembl:ENSP00000420927 intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99 psi-mi:pdk2_human(display_long)|uniprotkb:Pyruvate dehydrogenase kinase isoform 2(gene name synonym)|uniprotkb:PDK2(gene name)|psi-mi:PDK2(display_short)|uniprotkb:PDHK2(gene name synonym) psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Eiseler et al. (2007) pubmed:17707375|imex:IM-10904|mint:MINT-5222632 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7565229|mint:MINT-5222647|imex:IM-10904-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186828.1|refseq:NP_002602.2|refseq:NP_001186827.1|rcsb pdb:6LIO|rcsb pdb:6TMP|rcsb pdb:6TMQ|rcsb pdb:6TMZ|rcsb pdb:6TN0|rcsb pdb:6TN2|reactome:R-HSA-204174|reactome:R-HSA-5362517|ensembl:ENSG00000005882(gene)|ensembl:ENST00000503176(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004740"("pyruvate dehydrogenase (acetyl-transferring) kinase activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006885"(regulation of pH)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010510"(regulation of acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0010565"(regulation of cellular ketone metabolic process)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR018955|interpro:IPR036784|interpro:IPR036890|interpro:IPR039028|mint:Q15119|rcsb pdb:2BTZ|rcsb pdb:2BU2|rcsb pdb:2BU5|rcsb pdb:2BU6|rcsb pdb:2BU7|rcsb pdb:2BU8|rcsb pdb:4MP2|rcsb pdb:4MP7|rcsb pdb:4MPC|rcsb pdb:4MPE|rcsb pdb:4MPN|rcsb pdb:4V25|rcsb pdb:4V26|rcsb pdb:5J6A|rcsb pdb:5J71|rcsb pdb:5M4K|rcsb pdb:5M4M|rcsb pdb:5M4N|rcsb pdb:5M4P|rcsb pdb:6LIL|rcsb pdb:6LIN|mint:MINT-5222650(identity) refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-5222649(identity) - - - figure legend:F2A F2C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/15 2014/10/16 rogid:mGS3AxBLzr8a/x1q6z7RkS99WkQ9606 rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606 intact-crc:FFFCAC5AF5D81DCB|rigid:LQu2SsC6rPOt1v9BkK3NUmybcfI false - flag tag:?-?(MINT-5222655) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P60709 uniprotkb:O08852 intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821 intact:EBI-6666305|ensembl:ENSMUSP00000049296|uniprotkb:E9QJR6 psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:pkd1_mouse(display_long)|uniprotkb:Pkd1(gene name)|psi-mi:Pkd1(display_short)|uniprotkb:Autosomal dominant polycystic kidney disease 1 protein homolog(gene name synonym) psi-mi:"MI:0027"(cosedimentation) Eiseler et al. (2007) pubmed:17707375|imex:IM-10904|mint:MINT-5222632 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7565272|mint:MINT-5222699|imex:IM-10904-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N|mint:MINT-5222701(identity) ensembl:ENSMUSG00000032855(gene)|ensembl:ENSMUST00000035565(transcript)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002133"(polycystin complex)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007507"(heart development)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021915"(neural tube development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031514"(motile cilium)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034703"(cation channel complex)|go:"GO:0034704"(calcium channel complex)|go:"GO:0036303"(lymph vessel morphogenesis)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048806"(genitalia development)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0072177"(mesonephric duct development)|go:"GO:0072205"(metanephric collecting duct development)|go:"GO:0072218"(metanephric ascending thin limb development)|go:"GO:0072237"(metanephric proximal tubule development)|go:"GO:0072287"(metanephric distal tubule morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0198738"(cell-cell signaling by wnt)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000203(GPS)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000434(Polycystic kidney disease type 1 protein)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001304(C-type lectin)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002859(PKD/REJ-like protein)|interpro:IPR002889(Carbohydrate-binding WSC)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR006228(Polycystin cation channel)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014010(Egg jelly receptor, REJ-like)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR022409|interpro:IPR032675|interpro:IPR035986|interpro:IPR036392|interpro:IPR042060|mint:O08852|interpro:IPR000601(PKD)|refseq:NP_038658.2|dip:DIP-44233N|mint:MINT-5222706(identity) - - - figure legend:F2D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/15 2014/10/16 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606 rogid:GuuAhfakEvak5k2Zry2YxCjrQVk10090 intact-crc:9625BA6E5CB42433|rigid:LsMDSn7YOXLTVeiNJ2kIdCuNlcY false - mutation disrupting interaction:?-?(MINT-5222707) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O08852 uniprotkb:P60710 intact:EBI-6666305|ensembl:ENSMUSP00000049296|uniprotkb:E9QJR6 intact:EBI-353957|ensembl:ENSMUSP00000098066|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q3TI89|uniprotkb:Q3TVP6|uniprotkb:Q64316|uniprotkb:Q6ZWM3 psi-mi:pkd1_mouse(display_long)|uniprotkb:Pkd1(gene name)|psi-mi:Pkd1(display_short)|uniprotkb:Autosomal dominant polycystic kidney disease 1 protein homolog(gene name synonym) psi-mi:actb_mouse(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Eiseler et al. (2007) pubmed:17707375|imex:IM-10904|mint:MINT-5222632 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7565340|mint:MINT-5222669|imex:IM-10904-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032855(gene)|ensembl:ENSMUST00000035565(transcript)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002133"(polycystin complex)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007507"(heart development)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021915"(neural tube development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031514"(motile cilium)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034703"(cation channel complex)|go:"GO:0034704"(calcium channel complex)|go:"GO:0036303"(lymph vessel morphogenesis)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048806"(genitalia development)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0072177"(mesonephric duct development)|go:"GO:0072205"(metanephric collecting duct development)|go:"GO:0072218"(metanephric ascending thin limb development)|go:"GO:0072237"(metanephric proximal tubule development)|go:"GO:0072287"(metanephric distal tubule morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0198738"(cell-cell signaling by wnt)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000203(GPS)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000434(Polycystic kidney disease type 1 protein)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001304(C-type lectin)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002859(PKD/REJ-like protein)|interpro:IPR002889(Carbohydrate-binding WSC)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR006228(Polycystin cation channel)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014010(Egg jelly receptor, REJ-like)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR022409|interpro:IPR032675|interpro:IPR035986|interpro:IPR036392|interpro:IPR042060|mint:O08852|interpro:IPR000601(PKD)|refseq:NP_038658.2|dip:DIP-44233N|mint:MINT-5222670(identity) ensembl:ENSMUSG00000029580(gene)|ensembl:ENSMUST00000100497(transcript)|refseq:NP_031419.1|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60710|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5250924|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8856828|reactome:R-MMU-9035034|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|dip:DIP-31574N|mint:MINT-5222671(identity) - - - figure legend:F3|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-b16-f1)|taxid:10090(Mus musculus) - 2007/11/15 2014/10/16 rogid:GuuAhfakEvak5k2Zry2YxCjrQVk10090 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10090 intact-crc:45E2202AE8ACA697|rigid:S76FVzhqZutzWOg8tNGl+1I1nYE false green fluorescent protein tag:?-?(MINT-5222714) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0422"(immunostaining) uniprotkb:Q14247 uniprotkb:O08852 intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99 intact:EBI-6666305|ensembl:ENSMUSP00000049296|uniprotkb:E9QJR6 psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym) psi-mi:pkd1_mouse(display_long)|uniprotkb:Pkd1(gene name)|psi-mi:Pkd1(display_short)|uniprotkb:Autosomal dominant polycystic kidney disease 1 protein homolog(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Eiseler et al. (2007) pubmed:17707375|imex:IM-10904|mint:MINT-5222632 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7565521|mint:MINT-5222726|imex:IM-10904-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N|mint:MINT-5222728(identity) ensembl:ENSMUSG00000032855(gene)|ensembl:ENSMUST00000035565(transcript)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002133"(polycystin complex)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007507"(heart development)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021915"(neural tube development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031514"(motile cilium)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034703"(cation channel complex)|go:"GO:0034704"(calcium channel complex)|go:"GO:0036303"(lymph vessel morphogenesis)|go:"GO:0042813"(Wnt-activated receptor activity)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043588"(skin development)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048806"(genitalia development)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0060428"(lung epithelium development)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0072177"(mesonephric duct development)|go:"GO:0072205"(metanephric collecting duct development)|go:"GO:0072218"(metanephric ascending thin limb development)|go:"GO:0072237"(metanephric proximal tubule development)|go:"GO:0072287"(metanephric distal tubule morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0198738"(cell-cell signaling by wnt)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000203(GPS)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000434(Polycystic kidney disease type 1 protein)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR001304(C-type lectin)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002859(PKD/REJ-like protein)|interpro:IPR002889(Carbohydrate-binding WSC)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR006228(Polycystin cation channel)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014010(Egg jelly receptor, REJ-like)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR022409|interpro:IPR032675|interpro:IPR035986|interpro:IPR036392|interpro:IPR042060|mint:O08852|interpro:IPR000601(PKD)|refseq:NP_038658.2|dip:DIP-44233N|mint:MINT-5222736(identity) - - - figure legend:F4B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-panc89)|taxid:9606(Homo sapiens) - 2007/11/15 2014/10/16 rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606 rogid:GuuAhfakEvak5k2Zry2YxCjrQVk10090 intact-crc:01AE1F7D2B1FE46A|rigid:G92fwW7d+YCscofvYrLI6doykIo false - green fluorescent protein tag:?-?(MINT-5222744) - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0396"(predetermined participant)