#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:F1MKY4	uniprotkb:P08100	intact:EBI-1394240|uniprotkb:G3MXR1|ensembl:ENSBTAP00000018986|ensembl:ENSBTAP00000054330	intact:EBI-1394177|uniprotkb:Q16414|uniprotkb:Q2M249|ensembl:ENSP00000296271	psi-mi:f1mky4_bovin(display_long)|uniprotkb:ZFYVE9(gene name)|psi-mi:ZFYVE9(display_short)	psi-mi:opsd_human(display_long)|uniprotkb:RHO(gene name)|psi-mi:RHO(display_short)|uniprotkb:OPN2(gene name synonym)|uniprotkb:Opsin-2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chuang et al. (2007)	imex:IM-11880|pubmed:17693260	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1394192|imex:IM-11880-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_002686450.1|refseq:XP_015318256.1|ensembl:ENSBTAG00000014289(gene)|ensembl:ENSBTAT00000018986(transcript)|ensembl:ENSBTAT00000063202(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005829"(cytosol)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR024608|interpro:IPR035438|interpro:IPR037145	refseq:NP_000530.1|ensembl:ENSG00000163914(gene)|ensembl:ENST00000296271(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016038"(absorption of visible light)|go:"GO:0016056"(rhodopsin mediated signaling pathway)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0043052"(thermotaxis)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097381"(photoreceptor disc membrane)|go:"GO:1990913"(sperm head plasma membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000732(Rhodopsin)|interpro:IPR001760(Opsin)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR019477|interpro:IPR027430|rcsb pdb:4ZWJ|rcsb pdb:5DGY|rcsb pdb:5W0P|rcsb pdb:6CMO|reactome:R-HSA-2453902|reactome:R-HSA-2485179|reactome:R-HSA-2514859|reactome:R-HSA-418594|reactome:R-HSA-419771|reactome:R-HSA-5620916	psi-mi:"MI:0469"(intact)	comment:Homologous to O95405	-	comment:The bovine SARA protein aligned to residues 729-1425 of the human protein|figure legend:1C|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/12	2019/04/15	rogid:cEfXHvDsIK5z58kBAcTfJn3ZhdQ9913	rogid:ArgelSeCG9p+UzlgL9Ut843jZkA9606	intact-crc:737455035AF28AB4|rigid:VPDw14onmVRtd3quB78VIOUkT1k	false	sufficient binding region:?-?	sufficient binding region:310-348	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O95405	uniprotkb:P08100	intact:EBI-296817|ensembl:ENSP00000287727|ensembl:ENSP00000360647|uniprotkb:Q9UNE1|uniprotkb:Q9Y5R7|uniprotkb:Q5T0F6|uniprotkb:Q5T0F7	intact:EBI-1394177|uniprotkb:Q16414|uniprotkb:Q2M249|ensembl:ENSP00000296271	psi-mi:zfyv9_human(display_long)|uniprotkb:ZFYVE9(gene name)|psi-mi:ZFYVE9(display_short)|uniprotkb:MADHIP(gene name synonym)|uniprotkb:SARA(gene name synonym)|uniprotkb:SMADIP(gene name synonym)|uniprotkb:Mothers against decapentaplegic homolog-interacting protein(gene name synonym)|uniprotkb:Smad anchor for receptor activation(gene name synonym)|uniprotkb:Receptor activation anchor(gene name synonym)|uniprotkb:Novel serine protease(gene name synonym)	psi-mi:opsd_human(display_long)|uniprotkb:RHO(gene name)|psi-mi:RHO(display_short)|uniprotkb:OPN2(gene name synonym)|uniprotkb:Opsin-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chuang et al. (2007)	imex:IM-11880|pubmed:17693260	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1394254|imex:IM-11880-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157077(gene)|ensembl:ENST00000287727(transcript)|ensembl:ENST00000371591(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR024608|interpro:IPR035438|interpro:IPR037145|mint:O95405|rcsb pdb:1DEV|rcsb pdb:1MK2|rcsb pdb:4BKW|rcsb pdb:5MJY|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-3304356|reactome:R-HSA-3656532|refseq:NP_004790.2|refseq:NP_015563.2|refseq:XP_011540739.1	refseq:NP_000530.1|ensembl:ENSG00000163914(gene)|ensembl:ENST00000296271(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016038"(absorption of visible light)|go:"GO:0016056"(rhodopsin mediated signaling pathway)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0043052"(thermotaxis)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097381"(photoreceptor disc membrane)|go:"GO:1990913"(sperm head plasma membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000732(Rhodopsin)|interpro:IPR001760(Opsin)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR019477|interpro:IPR027430|rcsb pdb:4ZWJ|rcsb pdb:5DGY|rcsb pdb:5W0P|rcsb pdb:6CMO|reactome:R-HSA-2453902|reactome:R-HSA-2485179|reactome:R-HSA-2514859|reactome:R-HSA-418594|reactome:R-HSA-419771|reactome:R-HSA-5620916	psi-mi:"MI:0469"(intact)	-	-	figure legend:1E|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/12	2014/10/16	rogid:v3GnwyZAswVd59VtF27Ny2k7Ujc9606	rogid:ArgelSeCG9p+UzlgL9Ut843jZkA9606	intact-crc:E7DFA16A4B9CD758|rigid:o+pccnAy6CsiEnjZCeR3N9c8N+c	false	his tag:?-?	sufficient binding region:310-348|glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O95405	uniprotkb:Q13277	intact:EBI-296817|ensembl:ENSP00000287727|ensembl:ENSP00000360647|uniprotkb:Q9UNE1|uniprotkb:Q9Y5R7|uniprotkb:Q5T0F6|uniprotkb:Q5T0F7	intact:EBI-1394295|uniprotkb:O43750|uniprotkb:O43751|uniprotkb:Q15360|uniprotkb:B4DME0|ensembl:ENSP00000338562	psi-mi:zfyv9_human(display_long)|uniprotkb:ZFYVE9(gene name)|psi-mi:ZFYVE9(display_short)|uniprotkb:MADHIP(gene name synonym)|uniprotkb:SARA(gene name synonym)|uniprotkb:SMADIP(gene name synonym)|uniprotkb:Mothers against decapentaplegic homolog-interacting protein(gene name synonym)|uniprotkb:Smad anchor for receptor activation(gene name synonym)|uniprotkb:Receptor activation anchor(gene name synonym)|uniprotkb:Novel serine protease(gene name synonym)	psi-mi:stx3_human(display_long)|uniprotkb:STX3(gene name)|psi-mi:STX3(display_short)|uniprotkb:STX3A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chuang et al. (2007)	imex:IM-11880|pubmed:17693260	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1394323|imex:IM-11880-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157077(gene)|ensembl:ENST00000287727(transcript)|ensembl:ENST00000371591(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR024608|interpro:IPR035438|interpro:IPR037145|mint:O95405|rcsb pdb:1DEV|rcsb pdb:1MK2|rcsb pdb:4BKW|rcsb pdb:5MJY|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-3304356|reactome:R-HSA-3656532|refseq:NP_004790.2|refseq:NP_015563.2|refseq:XP_011540739.1	refseq:NP_004168.1|refseq:NP_001171511.1|refseq:XP_005274252.1|refseq:XP_005274257.1|ensembl:ENSG00000166900(gene)|ensembl:ENST00000337979(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031175"(neuron projection development)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR031186|mint:Q13277|reactome:R-HSA-449836	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 6C|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/12	2014/10/16	rogid:v3GnwyZAswVd59VtF27Ny2k7Ujc9606	rogid:M/ue1L+l8LnUJNpEWVZ/KWR5UjM9606	intact-crc:92D0194838DB7717|rigid:lddysuAyC/TkyB3qB5TnVqqbwLM	false	his tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P08100	uniprotkb:O95405	intact:EBI-1394177|uniprotkb:Q16414|uniprotkb:Q2M249|ensembl:ENSP00000296271	intact:EBI-296817|ensembl:ENSP00000287727|ensembl:ENSP00000360647|uniprotkb:Q9UNE1|uniprotkb:Q9Y5R7|uniprotkb:Q5T0F6|uniprotkb:Q5T0F7	psi-mi:opsd_human(display_long)|uniprotkb:RHO(gene name)|psi-mi:RHO(display_short)|uniprotkb:OPN2(gene name synonym)|uniprotkb:Opsin-2(gene name synonym)	psi-mi:zfyv9_human(display_long)|uniprotkb:ZFYVE9(gene name)|psi-mi:ZFYVE9(display_short)|uniprotkb:MADHIP(gene name synonym)|uniprotkb:SARA(gene name synonym)|uniprotkb:SMADIP(gene name synonym)|uniprotkb:Mothers against decapentaplegic homolog-interacting protein(gene name synonym)|uniprotkb:Smad anchor for receptor activation(gene name synonym)|uniprotkb:Receptor activation anchor(gene name synonym)|uniprotkb:Novel serine protease(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chuang et al. (2007)	imex:IM-11880|pubmed:17693260	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1394272|imex:IM-11880-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000530.1|ensembl:ENSG00000163914(gene)|ensembl:ENST00000296271(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016038"(absorption of visible light)|go:"GO:0016056"(rhodopsin mediated signaling pathway)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0043052"(thermotaxis)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097381"(photoreceptor disc membrane)|go:"GO:1990913"(sperm head plasma membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000732(Rhodopsin)|interpro:IPR001760(Opsin)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR019477|interpro:IPR027430|rcsb pdb:4ZWJ|rcsb pdb:5DGY|rcsb pdb:5W0P|rcsb pdb:6CMO|reactome:R-HSA-2453902|reactome:R-HSA-2485179|reactome:R-HSA-2514859|reactome:R-HSA-418594|reactome:R-HSA-419771|reactome:R-HSA-5620916	ensembl:ENSG00000157077(gene)|ensembl:ENST00000287727(transcript)|ensembl:ENST00000371591(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR024608|interpro:IPR035438|interpro:IPR037145|mint:O95405|rcsb pdb:1DEV|rcsb pdb:1MK2|rcsb pdb:4BKW|rcsb pdb:5MJY|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-3304356|reactome:R-HSA-3656532|refseq:NP_004790.2|refseq:NP_015563.2|refseq:XP_011540739.1	psi-mi:"MI:0469"(intact)	-	-	figure legend:1F|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-retina)|taxid:10090(Mus musculus retina)	-	2007/09/12	2014/10/16	rogid:ArgelSeCG9p+UzlgL9Ut843jZkA9606	rogid:v3GnwyZAswVd59VtF27Ny2k7Ujc9606	intact-crc:8704D31C4FCE4947|rigid:o+pccnAy6CsiEnjZCeR3N9c8N+c	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q15075	uniprotkb:P08100	intact:EBI-298113|uniprotkb:Q14221|ensembl:ENSP00000317955	intact:EBI-1394177|uniprotkb:Q16414|uniprotkb:Q2M249|ensembl:ENSP00000296271	psi-mi:eea1_human(display_long)|uniprotkb:EEA1(gene name)|psi-mi:EEA1(display_short)|uniprotkb:ZFYVE2(gene name synonym)|uniprotkb:Endosome-associated protein p162(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 2(gene name synonym)	psi-mi:opsd_human(display_long)|uniprotkb:RHO(gene name)|psi-mi:RHO(display_short)|uniprotkb:OPN2(gene name synonym)|uniprotkb:Opsin-2(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chuang et al. (2007)	imex:IM-11880|pubmed:17693260	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1394288|imex:IM-11880-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102189(gene)|ensembl:ENST00000322349(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005969"(serine-pyruvate aminotransferase complex)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044308"(axonal spine)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|mint:Q15075|rcsb pdb:1HYI|rcsb pdb:1HYJ|rcsb pdb:1JOC|rcsb pdb:3MJH|reactome:R-HSA-168138|refseq:NP_003557.2	refseq:NP_000530.1|ensembl:ENSG00000163914(gene)|ensembl:ENST00000296271(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005502"(11-cis retinal binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007601"(visual perception)|go:"GO:0007602"(phototransduction)|go:"GO:0007603"(phototransduction, visible light)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016038"(absorption of visible light)|go:"GO:0016056"(rhodopsin mediated signaling pathway)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0043052"(thermotaxis)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0050960"(detection of temperature stimulus involved in thermoception)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097381"(photoreceptor disc membrane)|go:"GO:1990913"(sperm head plasma membrane)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000732(Rhodopsin)|interpro:IPR001760(Opsin)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR019477|interpro:IPR027430|rcsb pdb:4ZWJ|rcsb pdb:5DGY|rcsb pdb:5W0P|rcsb pdb:6CMO|reactome:R-HSA-2453902|reactome:R-HSA-2485179|reactome:R-HSA-2514859|reactome:R-HSA-418594|reactome:R-HSA-419771|reactome:R-HSA-5620916	go:"GO:0005769"(early endosome)	-	-	figure legend:1G|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/09/12	2014/10/16	rogid:aKGquyBsTFm+hhbJiIbz1Lv88Hw9606	rogid:ArgelSeCG9p+UzlgL9Ut843jZkA9606	intact-crc:5F0BE7311732406D|rigid:JvcLHDwVKLU7Uqkzbu1+hFxfnZs	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q15075	uniprotkb:O95405	intact:EBI-298113|uniprotkb:Q14221|ensembl:ENSP00000317955	intact:EBI-296817|ensembl:ENSP00000287727|ensembl:ENSP00000360647|uniprotkb:Q9UNE1|uniprotkb:Q9Y5R7|uniprotkb:Q5T0F6|uniprotkb:Q5T0F7	psi-mi:eea1_human(display_long)|uniprotkb:EEA1(gene name)|psi-mi:EEA1(display_short)|uniprotkb:ZFYVE2(gene name synonym)|uniprotkb:Endosome-associated protein p162(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 2(gene name synonym)	psi-mi:zfyv9_human(display_long)|uniprotkb:ZFYVE9(gene name)|psi-mi:ZFYVE9(display_short)|uniprotkb:MADHIP(gene name synonym)|uniprotkb:SARA(gene name synonym)|uniprotkb:SMADIP(gene name synonym)|uniprotkb:Mothers against decapentaplegic homolog-interacting protein(gene name synonym)|uniprotkb:Smad anchor for receptor activation(gene name synonym)|uniprotkb:Receptor activation anchor(gene name synonym)|uniprotkb:Novel serine protease(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chuang et al. (2007)	imex:IM-11880|pubmed:17693260	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1394288|imex:IM-11880-6	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000102189(gene)|ensembl:ENST00000322349(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005969"(serine-pyruvate aminotransferase complex)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044308"(axonal spine)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017455(Zinc finger, FYVE-related)|mint:Q15075|rcsb pdb:1HYI|rcsb pdb:1HYJ|rcsb pdb:1JOC|rcsb pdb:3MJH|reactome:R-HSA-168138|refseq:NP_003557.2	ensembl:ENSG00000157077(gene)|ensembl:ENST00000287727(transcript)|ensembl:ENST00000371591(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR024608|interpro:IPR035438|interpro:IPR037145|mint:O95405|rcsb pdb:1DEV|rcsb pdb:1MK2|rcsb pdb:4BKW|rcsb pdb:5MJY|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-3304356|reactome:R-HSA-3656532|refseq:NP_004790.2|refseq:NP_015563.2|refseq:XP_011540739.1	go:"GO:0005769"(early endosome)	-	-	figure legend:1G|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/09/12	2014/10/16	rogid:aKGquyBsTFm+hhbJiIbz1Lv88Hw9606	rogid:v3GnwyZAswVd59VtF27Ny2k7Ujc9606	intact-crc:5F0BE7311732406D|rigid:JvcLHDwVKLU7Uqkzbu1+hFxfnZs	false	-	flag tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:Q13277	uniprotkb:O95405	intact:EBI-1394295|uniprotkb:O43750|uniprotkb:O43751|uniprotkb:Q15360|uniprotkb:B4DME0|ensembl:ENSP00000338562	intact:EBI-296817|ensembl:ENSP00000287727|ensembl:ENSP00000360647|uniprotkb:Q9UNE1|uniprotkb:Q9Y5R7|uniprotkb:Q5T0F6|uniprotkb:Q5T0F7	psi-mi:stx3_human(display_long)|uniprotkb:STX3(gene name)|psi-mi:STX3(display_short)|uniprotkb:STX3A(gene name synonym)	psi-mi:zfyv9_human(display_long)|uniprotkb:ZFYVE9(gene name)|psi-mi:ZFYVE9(display_short)|uniprotkb:MADHIP(gene name synonym)|uniprotkb:SARA(gene name synonym)|uniprotkb:SMADIP(gene name synonym)|uniprotkb:Mothers against decapentaplegic homolog-interacting protein(gene name synonym)|uniprotkb:Smad anchor for receptor activation(gene name synonym)|uniprotkb:Receptor activation anchor(gene name synonym)|uniprotkb:Novel serine protease(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chuang et al. (2007)	imex:IM-11880|pubmed:17693260	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1394315|imex:IM-11880-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004168.1|refseq:NP_001171511.1|refseq:XP_005274252.1|refseq:XP_005274257.1|ensembl:ENSG00000166900(gene)|ensembl:ENST00000337979(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031175"(neuron projection development)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR031186|mint:Q13277|reactome:R-HSA-449836	ensembl:ENSG00000157077(gene)|ensembl:ENST00000287727(transcript)|ensembl:ENST00000371591(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR024608|interpro:IPR035438|interpro:IPR037145|mint:O95405|rcsb pdb:1DEV|rcsb pdb:1MK2|rcsb pdb:4BKW|rcsb pdb:5MJY|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-3304356|reactome:R-HSA-3656532|refseq:NP_004790.2|refseq:NP_015563.2|refseq:XP_011540739.1	go:"GO:0005769"(early endosome)|go:"GO:0031410"(cytoplasmic vesicle)	-	-	figure legend:Fig. 6B and Supp. Fig. 9|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/09/12	2014/10/16	rogid:M/ue1L+l8LnUJNpEWVZ/KWR5UjM9606	rogid:v3GnwyZAswVd59VtF27Ny2k7Ujc9606	intact-crc:6B1CBB8BF870100E|rigid:lddysuAyC/TkyB3qB5TnVqqbwLM	false	myc tag:?-?	flag tag:?-?	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)
uniprotkb:O95405	uniprotkb:Q13277	intact:EBI-296817|ensembl:ENSP00000287727|ensembl:ENSP00000360647|uniprotkb:Q9UNE1|uniprotkb:Q9Y5R7|uniprotkb:Q5T0F6|uniprotkb:Q5T0F7	intact:EBI-1394295|uniprotkb:O43750|uniprotkb:O43751|uniprotkb:Q15360|uniprotkb:B4DME0|ensembl:ENSP00000338562	psi-mi:zfyv9_human(display_long)|uniprotkb:ZFYVE9(gene name)|psi-mi:ZFYVE9(display_short)|uniprotkb:MADHIP(gene name synonym)|uniprotkb:SARA(gene name synonym)|uniprotkb:SMADIP(gene name synonym)|uniprotkb:Mothers against decapentaplegic homolog-interacting protein(gene name synonym)|uniprotkb:Smad anchor for receptor activation(gene name synonym)|uniprotkb:Receptor activation anchor(gene name synonym)|uniprotkb:Novel serine protease(gene name synonym)	psi-mi:stx3_human(display_long)|uniprotkb:STX3(gene name)|psi-mi:STX3(display_short)|uniprotkb:STX3A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chuang et al. (2007)	imex:IM-11880|pubmed:17693260	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1394347|imex:IM-11880-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000157077(gene)|ensembl:ENST00000287727(transcript)|ensembl:ENST00000371591(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR024608|interpro:IPR035438|interpro:IPR037145|mint:O95405|rcsb pdb:1DEV|rcsb pdb:1MK2|rcsb pdb:4BKW|rcsb pdb:5MJY|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-3304356|reactome:R-HSA-3656532|refseq:NP_004790.2|refseq:NP_015563.2|refseq:XP_011540739.1	refseq:NP_004168.1|refseq:NP_001171511.1|refseq:XP_005274252.1|refseq:XP_005274257.1|ensembl:ENSG00000166900(gene)|ensembl:ENST00000337979(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031175"(neuron projection development)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0042470"(melanosome)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR031186|mint:Q13277|reactome:R-HSA-449836	psi-mi:"MI:0469"(intact)	-	-	figure legend:Fig. 6D|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/09/12	2014/10/16	rogid:v3GnwyZAswVd59VtF27Ny2k7Ujc9606	rogid:M/ue1L+l8LnUJNpEWVZ/KWR5UjM9606	intact-crc:57721452C3D28CBA|rigid:lddysuAyC/TkyB3qB5TnVqqbwLM	false	flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
chebi:"CHEBI:17283"	uniprotkb:O95405	intact:EBI-1257113	intact:EBI-296817|ensembl:ENSP00000287727|ensembl:ENSP00000360647|uniprotkb:Q9UNE1|uniprotkb:Q9Y5R7|uniprotkb:Q5T0F6|uniprotkb:Q5T0F7	psi-mi:pi3p(display_short)|psi-mi:"CHEBI:17283"(display_long)	psi-mi:zfyv9_human(display_long)|uniprotkb:ZFYVE9(gene name)|psi-mi:ZFYVE9(display_short)|uniprotkb:MADHIP(gene name synonym)|uniprotkb:SARA(gene name synonym)|uniprotkb:SMADIP(gene name synonym)|uniprotkb:Mothers against decapentaplegic homolog-interacting protein(gene name synonym)|uniprotkb:Smad anchor for receptor activation(gene name synonym)|uniprotkb:Receptor activation anchor(gene name synonym)|uniprotkb:Novel serine protease(gene name synonym)	psi-mi:"MI:0049"(filter binding)	Chuang et al. (2007)	imex:IM-11880|pubmed:17693260	taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1394382|imex:IM-11880-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0328"(small molecule)	psi-mi:"MI:0326"(protein)	-	ensembl:ENSG00000157077(gene)|ensembl:ENST00000287727(transcript)|ensembl:ENST00000371591(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005769"(early endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR024608|interpro:IPR035438|interpro:IPR037145|mint:O95405|rcsb pdb:1DEV|rcsb pdb:1MK2|rcsb pdb:4BKW|rcsb pdb:5MJY|reactome:R-HSA-2173788|reactome:R-HSA-2173789|reactome:R-HSA-3304356|reactome:R-HSA-3656532|refseq:NP_004790.2|refseq:NP_015563.2|refseq:XP_011540739.1	go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)	-	-	figure legend:Supp. Fig. 2|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/12	2014/10/16	-	rogid:v3GnwyZAswVd59VtF27Ny2k7Ujc9606	intact-crc:8B613E1F4C5CD10A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)