#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P50580 uniprotkb:P19339 intact:EBI-7550171|intact:MINT-1857756|ensembl:ENSMUSP00000026425|ensembl:ENSMUSP00000114434 intact:EBI-199576|uniprotkb:P19340|uniprotkb:Q0KHV2|uniprotkb:Q26466|uniprotkb:Q2MGN7|uniprotkb:Q2MGN8|uniprotkb:Q2MGN9|uniprotkb:Q2MGP1|uniprotkb:Q7KVU6|uniprotkb:Q7YZ92|uniprotkb:Q8IRQ1|uniprotkb:Q99141|uniprotkb:Q9TYF5|uniprotkb:Q9W3S6|uniprotkb:A4V435|uniprotkb:A4V437|uniprotkb:A4V434|uniprotkb:A4V436|uniprotkb:C9QP40|uniprotkb:D0IQK2|uniprotkb:D3PFI6|uniprotkb:E1JJI8|uniprotkb:E1JJI9|uniprotkb:E1JJJ0|uniprotkb:E1JJJ2|uniprotkb:E1JJJ3|ensemblmetazoa:FBpp0303697|ensemblmetazoa:FBpp0303704|ensemblmetazoa:FBpp0303710 psi-mi:pa2g4_mouse(display_long)|uniprotkb:Ebp1(gene name synonym)|uniprotkb:Pa2g4(gene name)|psi-mi:Pa2g4(display_short)|uniprotkb:Plfap(gene name synonym)|uniprotkb:Proliferation-associated protein 1(gene name synonym)|uniprotkb:Protein p38-2G4(gene name synonym)|uniprotkb:Mpp1(gene name synonym)|uniprotkb:IRES-specific cellular trans-acting factor 45 kDa(gene name synonym) psi-mi:sxl_drome(display_long)|uniprotkb:Sxl(gene name)|psi-mi:Sxl(display_short)|uniprotkb:Sx1(gene name synonym)|uniprotkb:CG43770(orf name) psi-mi:"MI:0096"(pull down) Monie et al. (2007) pubmed:17690690|imex:IM-14007|mint:MINT-5226334 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7550205|mint:MINT-5226344|imex:IM-14007-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035249.1|ensembl:ENSMUSG00000025364(gene)|ensembl:ENSMUST00000026425(transcript)|ensembl:ENSMUST00000131728(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR018349|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:P50580|rcsb pdb:2V6C|rcsb pdb:6SWA|reactome:R-MMU-6798695|mint:MINT-5226346(identity) refseq:NP_727161.3|refseq:NP_001027062.1|refseq:NP_001027063.1|refseq:NP_001027064.1|refseq:NP_001027065.1|refseq:NP_001027066.1|refseq:NP_001162686.1|refseq:NP_001162687.1|refseq:NP_001162688.1|refseq:NP_001162689.1|refseq:NP_001162690.1|refseq:NP_524791.3|refseq:NP_727160.2|refseq:NP_727162.2|refseq:NP_727163.2|refseq:NP_727164.2|refseq:NP_727165.2|refseq:NP_727166.2|refseq:NP_727167.2|refseq:NP_727168.1|refseq:NP_001259305.1|refseq:NP_001259306.1|flybase:FBgn0264270|dip:DIP-44607N|ensemblmetazoa:FBgn0264270(gene)|ensemblmetazoa:FBtr0331255(transcript)|ensemblmetazoa:FBtr0331262(transcript)|ensemblmetazoa:FBtr0331268(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007530"(sex determination)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0007548"(sex differentiation)|go:"GO:0007549"(dosage compensation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0009994"(oocyte differentiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018993"(somatic sex determination)|go:"GO:0030237"(female sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990399"(epithelium regeneration)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006546(Sex-lethal splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P19339|rcsb pdb:1B7F|rcsb pdb:1SXL|rcsb pdb:2SXL|rcsb pdb:3SXL|rcsb pdb:4QQB|mint:MINT-5226347(identity) - comment:mint|function:"May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly (By similarity). Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site). Together with PTBP1 is required for the translation initiation on the foot-and-mouth disease virus (FMDV) IRES" - figure legend:F3|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/27 2014/10/16 rogid:00qNeBIV6MQIU5EgEQI6zWdyPJ010090 rogid:OOLyyjkFbL8POQarQfx8Yhy8SV47227 intact-crc:8286F14E62085E3C|rigid:wYBsamXaHnne0l2zaRtn637OuvU false binding-associated region:1-360(MINT-5226349) glutathione s tranferase tag:?-?(MINT-5226395) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19339 uniprotkb:Q9CW46 intact:EBI-199576|uniprotkb:P19340|uniprotkb:Q0KHV2|uniprotkb:Q26466|uniprotkb:Q2MGN7|uniprotkb:Q2MGN8|uniprotkb:Q2MGN9|uniprotkb:Q2MGP1|uniprotkb:Q7KVU6|uniprotkb:Q7YZ92|uniprotkb:Q8IRQ1|uniprotkb:Q99141|uniprotkb:Q9TYF5|uniprotkb:Q9W3S6|uniprotkb:A4V435|uniprotkb:A4V437|uniprotkb:A4V434|uniprotkb:A4V436|uniprotkb:C9QP40|uniprotkb:D0IQK2|uniprotkb:D3PFI6|uniprotkb:E1JJI8|uniprotkb:E1JJI9|uniprotkb:E1JJJ0|uniprotkb:E1JJJ2|uniprotkb:E1JJJ3|ensemblmetazoa:FBpp0303697|ensemblmetazoa:FBpp0303704|ensemblmetazoa:FBpp0303710 intact:EBI-644967|uniprotkb:Q5DTT6|uniprotkb:Q811K0|uniprotkb:Q8C3Z1|uniprotkb:Q8CA14|ensembl:ENSMUSP00000111150|ensembl:ENSMUSP00000151195 psi-mi:sxl_drome(display_long)|uniprotkb:Sxl(gene name)|psi-mi:Sxl(display_short)|uniprotkb:Sx1(gene name synonym)|uniprotkb:CG43770(orf name) psi-mi:ravr1_mouse(display_long)|uniprotkb:Protein raver-1(gene name synonym)|uniprotkb:Raver1(gene name)|psi-mi:Raver1(display_short)|uniprotkb:Kiaa1978(gene name synonym) psi-mi:"MI:0096"(pull down) Monie et al. (2007) pubmed:17690690|imex:IM-14007|mint:MINT-5226334 taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7550312|mint:MINT-5226399|imex:IM-14007-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_727161.3|refseq:NP_001027062.1|refseq:NP_001027063.1|refseq:NP_001027064.1|refseq:NP_001027065.1|refseq:NP_001027066.1|refseq:NP_001162686.1|refseq:NP_001162687.1|refseq:NP_001162688.1|refseq:NP_001162689.1|refseq:NP_001162690.1|refseq:NP_524791.3|refseq:NP_727160.2|refseq:NP_727162.2|refseq:NP_727163.2|refseq:NP_727164.2|refseq:NP_727165.2|refseq:NP_727166.2|refseq:NP_727167.2|refseq:NP_727168.1|refseq:NP_001259305.1|refseq:NP_001259306.1|flybase:FBgn0264270|dip:DIP-44607N|ensemblmetazoa:FBgn0264270(gene)|ensemblmetazoa:FBtr0331255(transcript)|ensemblmetazoa:FBtr0331262(transcript)|ensemblmetazoa:FBtr0331268(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007446"(imaginal disc growth)|go:"GO:0007530"(sex determination)|go:"GO:0007541"("sex determination, primary response to X:A ratio")|go:"GO:0007548"(sex differentiation)|go:"GO:0007549"(dosage compensation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0009994"(oocyte differentiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018993"(somatic sex determination)|go:"GO:0030237"(female sex determination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990399"(epithelium regeneration)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000035"(regulation of stem cell division)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006546(Sex-lethal splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P19339|rcsb pdb:1B7F|rcsb pdb:1SXL|rcsb pdb:2SXL|rcsb pdb:3SXL|rcsb pdb:4QQB|mint:MINT-5226406(identity) refseq:NP_082187.1|ensembl:ENSMUSG00000010205(gene)|ensembl:ENSMUSG00000111497(gene)|ensembl:ENSMUST00000115487(transcript)|ensembl:ENSMUST00000217359(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034633|interpro:IPR034635|interpro:IPR035979|mint:Q9CW46|rcsb pdb:1WI6|rcsb pdb:3ZZY|rcsb pdb:3ZZZ|dip:DIP-44609N|mint:MINT-5226401(identity) - - - figure legend:F3|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/27 2014/10/16 rogid:OOLyyjkFbL8POQarQfx8Yhy8SV47227 rogid:8tlOX5yFmrXkpW1qGwJLK4alHqM10090 intact-crc:5BCF8A9C9E8103D2|rigid:J7m12cF7Fewobcn6K28jhcUzGHU false glutathione s tranferase tag:?-?(MINT-5226407) binding-associated region:1-455(MINT-5226402) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P50580 uniprotkb:P17225 intact:EBI-7550171|intact:MINT-1857756|ensembl:ENSMUSP00000026425|ensembl:ENSMUSP00000114434 intact:EBI-7550348|intact:MINT-1862139 psi-mi:pa2g4_mouse(display_long)|uniprotkb:Ebp1(gene name synonym)|uniprotkb:Pa2g4(gene name)|psi-mi:Pa2g4(display_short)|uniprotkb:Plfap(gene name synonym)|uniprotkb:Proliferation-associated protein 1(gene name synonym)|uniprotkb:Protein p38-2G4(gene name synonym)|uniprotkb:Mpp1(gene name synonym)|uniprotkb:IRES-specific cellular trans-acting factor 45 kDa(gene name synonym) psi-mi:ptbp1_mouse(display_long)|uniprotkb:Ptbp1(gene name)|psi-mi:Ptbp1(display_short)|uniprotkb:Ptb(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein I(gene name synonym) psi-mi:"MI:0096"(pull down) Monie et al. (2007) pubmed:17690690|imex:IM-14007|mint:MINT-5226334 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7550369|mint:MINT-5226412|imex:IM-14007-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035249.1|ensembl:ENSMUSG00000025364(gene)|ensembl:ENSMUST00000026425(transcript)|ensembl:ENSMUST00000131728(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR018349|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:P50580|rcsb pdb:2V6C|rcsb pdb:6SWA|reactome:R-MMU-6798695|mint:MINT-5226414(identity) interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P17225|interpro:IPR035979|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0022008"(neurogenesis)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1904411"(positive regulation of secretory granule organization)|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|interpro:IPR034798|interpro:IPR035000|interpro:IPR021790|mint:MINT-5226419(identity) - comment:mint|function:"May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly (By similarity). Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site). Together with PTBP1 is required for the translation initiation on the foot-and-mouth disease virus (FMDV) IRES" comment:mint|function:Plays a role in pre-mRNA splicing. Binds to the polypyrimidine tract of introns. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA figure legend:F3|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/27 2014/10/16 rogid:00qNeBIV6MQIU5EgEQI6zWdyPJ010090 rogid:u6aYhdXA91t5/EZlGcvlP0OAimg10090 intact-crc:2B98ABBC13E07615|rigid:DVOFgQNnRTh63I9Qf2N7yF1cnLk false binding-associated region:1-375(MINT-5226415) glutathione s tranferase tag:?-?(MINT-5226420) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P17225 uniprotkb:Q9CW46 intact:EBI-7550348|intact:MINT-1862139 intact:EBI-644967|uniprotkb:Q5DTT6|uniprotkb:Q811K0|uniprotkb:Q8C3Z1|uniprotkb:Q8CA14|ensembl:ENSMUSP00000111150|ensembl:ENSMUSP00000151195 psi-mi:ptbp1_mouse(display_long)|uniprotkb:Ptbp1(gene name)|psi-mi:Ptbp1(display_short)|uniprotkb:Ptb(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein I(gene name synonym) psi-mi:ravr1_mouse(display_long)|uniprotkb:Protein raver-1(gene name synonym)|uniprotkb:Raver1(gene name)|psi-mi:Raver1(display_short)|uniprotkb:Kiaa1978(gene name synonym) psi-mi:"MI:0096"(pull down) Monie et al. (2007) pubmed:17690690|imex:IM-14007|mint:MINT-5226334 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7550405|mint:MINT-5226424|imex:IM-14007-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P17225|interpro:IPR035979|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0022008"(neurogenesis)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1904411"(positive regulation of secretory granule organization)|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|interpro:IPR034798|interpro:IPR035000|interpro:IPR021790|mint:MINT-5226433(identity) refseq:NP_082187.1|ensembl:ENSMUSG00000010205(gene)|ensembl:ENSMUSG00000111497(gene)|ensembl:ENSMUST00000115487(transcript)|ensembl:ENSMUST00000217359(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034633|interpro:IPR034635|interpro:IPR035979|mint:Q9CW46|rcsb pdb:1WI6|rcsb pdb:3ZZY|rcsb pdb:3ZZZ|dip:DIP-44609N|mint:MINT-5226426(identity) - comment:mint|function:Plays a role in pre-mRNA splicing. Binds to the polypyrimidine tract of introns. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA - figure legend:F3|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/27 2014/10/16 rogid:u6aYhdXA91t5/EZlGcvlP0OAimg10090 rogid:8tlOX5yFmrXkpW1qGwJLK4alHqM10090 intact-crc:293F0FA6AEEAC494|rigid:xevFF/4KZ9bwZcyRE4HVssO00lY false glutathione s tranferase tag:?-?(MINT-5226434) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)