#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P01258	uniprotkb:Q01814	intact:EBI-1018474|uniprotkb:Q13935|uniprotkb:Q13937|uniprotkb:Q52LX7|uniprotkb:B7ZL39|ensembl:ENSP00000331746|ensembl:ENSP00000379657	intact:EBI-1174243|uniprotkb:O00766|uniprotkb:Q12994|uniprotkb:Q16818|ensembl:ENSP00000353414|ensembl:ENSP00000494716	psi-mi:calc_human(display_long)|uniprotkb:CALCA(gene name)|psi-mi:CALCA(display_short)|uniprotkb:CALC1(gene name synonym)	psi-mi:at2b2_human(display_long)|uniprotkb:ATP2B2(gene name)|psi-mi:ATP2B2(display_short)|uniprotkb:PMCA2(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 2(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Holton et al. (2007)	pubmed:17689535|imex:IM-10991|mint:MINT-5220120	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7542762|mint:MINT-5203983|imex:IM-10991-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001029124.1|refseq:NP_001732.1|ensembl:ENSG00000110680(gene)|ensembl:ENST00000331587(transcript)|ensembl:ENST00000396372(transcript)|go:"GO:0001984"(artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007566"(embryo implantation)|go:"GO:0007631"(feeding behavior)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0009408"(response to heat)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0031716"(calcitonin receptor binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045986"(negative regulation of smooth muscle contraction)|go:"GO:0048265"(response to pain)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001693(Calcitonin-like)|interpro:IPR018360|interpro:IPR021116|interpro:IPR021117|interpro:IPR021118|mint:P01258|rcsb pdb:2JXZ|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|reactome:R-HSA-977225|refseq:XP_016873772.1|refseq:XP_016873773.1|mint:MINT-5203984(identity)	refseq:NP_001001331.1|refseq:XP_005265236.1|refseq:XP_011532054.1|refseq:XP_006713238.1|ensembl:ENSG00000157087(gene)|ensembl:ENST00000360273(transcript)|ensembl:ENST00000645850(transcript)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1905059"(P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030322|interpro:IPR036412|interpro:IPR044492|mint:Q01814|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_001317540.1|refseq:XP_016861970.1|refseq:XP_016861971.1|refseq:XP_016861972.1|refseq:XP_016861973.1|refseq:XP_016861975.1|refseq:XP_016861978.1|mint:MINT-5203986(identity)	-	-	-	figure legend:F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2007/10/01	2018/09/18	rogid:LMHetYvCTJzVQ6Gu2beLPywSwtg9606	rogid:bCD7j13UJUgWoSHShHLKJBiVGJM9606	intact-crc:05F13A2A0E25E583|rigid:LkU9Ch1XSLzupB7ouKpNVEeIAqo	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P01258	uniprotkb:P23634	intact:EBI-1018474|uniprotkb:Q13935|uniprotkb:Q13937|uniprotkb:Q52LX7|uniprotkb:B7ZL39|ensembl:ENSP00000331746|ensembl:ENSP00000379657	intact:EBI-1174388|uniprotkb:Q13450|uniprotkb:Q13452|uniprotkb:Q13455|uniprotkb:Q16817|uniprotkb:Q7Z3S1|uniprotkb:B1APW6|uniprotkb:B1APW5	psi-mi:calc_human(display_long)|uniprotkb:CALCA(gene name)|psi-mi:CALCA(display_short)|uniprotkb:CALC1(gene name synonym)	psi-mi:at2b4_human(display_long)|uniprotkb:Plasma membrane calcium ATPase isoform 4(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 4(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 1(gene name synonym)|uniprotkb:ATP2B4(gene name)|psi-mi:ATP2B4(display_short)|uniprotkb:ATP2B2(gene name synonym)|uniprotkb:MXRA1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Holton et al. (2007)	pubmed:17689535|imex:IM-10991|mint:MINT-5220120	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7542762|mint:MINT-5203983|imex:IM-10991-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001029124.1|refseq:NP_001732.1|ensembl:ENSG00000110680(gene)|ensembl:ENST00000331587(transcript)|ensembl:ENST00000396372(transcript)|go:"GO:0001984"(artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007566"(embryo implantation)|go:"GO:0007631"(feeding behavior)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0009408"(response to heat)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0031716"(calcitonin receptor binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045986"(negative regulation of smooth muscle contraction)|go:"GO:0048265"(response to pain)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001693(Calcitonin-like)|interpro:IPR018360|interpro:IPR021116|interpro:IPR021117|interpro:IPR021118|mint:P01258|rcsb pdb:2JXZ|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|reactome:R-HSA-977225|refseq:XP_016873772.1|refseq:XP_016873773.1|mint:MINT-5203984(identity)	refseq:NP_001001396.1|refseq:NP_001675.3|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030018"(Z disc)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036487"(nitric-oxide synthase inhibitor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097228"(sperm principal piece)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098736"(negative regulation of the force of heart contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900082"(negative regulation of arginine catabolic process)|go:"GO:1901660"(calcium ion export)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902548"(negative regulation of cellular response to vascular endothelial growth factor stimulus)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903249"(negative regulation of citrulline biosynthetic process)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905145"(cellular response to acetylcholine)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|rcsb pdb:1CFF|rcsb pdb:2KNE|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|mint:P23634|dip:DIP-6128N|mint:MINT-5203985(identity)	-	-	-	figure legend:F1|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mcf7)|taxid:9606(Homo sapiens  mammary carcinoma cells)	-	2007/10/01	2018/09/18	rogid:LMHetYvCTJzVQ6Gu2beLPywSwtg9606	rogid:XAjzRea7vq4vsbCVKdZRYIWvfBM9606	intact-crc:05F13A2A0E25E583|rigid:LkU9Ch1XSLzupB7ouKpNVEeIAqo	false	-	-	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P23634	uniprotkb:P01258	intact:EBI-1174388|uniprotkb:Q13450|uniprotkb:Q13452|uniprotkb:Q13455|uniprotkb:Q16817|uniprotkb:Q7Z3S1|uniprotkb:B1APW6|uniprotkb:B1APW5	intact:EBI-1018474|uniprotkb:Q13935|uniprotkb:Q13937|uniprotkb:Q52LX7|uniprotkb:B7ZL39|ensembl:ENSP00000331746|ensembl:ENSP00000379657	psi-mi:at2b4_human(display_long)|uniprotkb:Plasma membrane calcium ATPase isoform 4(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 4(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 1(gene name synonym)|uniprotkb:ATP2B4(gene name)|psi-mi:ATP2B4(display_short)|uniprotkb:ATP2B2(gene name synonym)|uniprotkb:MXRA1(gene name synonym)	psi-mi:calc_human(display_long)|uniprotkb:CALCA(gene name)|psi-mi:CALCA(display_short)|uniprotkb:CALC1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Holton et al. (2007)	pubmed:17689535|imex:IM-10991|mint:MINT-5220120	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7542824|mint:MINT-5204003|imex:IM-10991-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001001396.1|refseq:NP_001675.3|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030018"(Z disc)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036487"(nitric-oxide synthase inhibitor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097228"(sperm principal piece)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098736"(negative regulation of the force of heart contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900082"(negative regulation of arginine catabolic process)|go:"GO:1901660"(calcium ion export)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902548"(negative regulation of cellular response to vascular endothelial growth factor stimulus)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903249"(negative regulation of citrulline biosynthetic process)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905145"(cellular response to acetylcholine)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|rcsb pdb:1CFF|rcsb pdb:2KNE|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|mint:P23634|dip:DIP-6128N|mint:MINT-5204008(identity)	refseq:NP_001029124.1|refseq:NP_001732.1|ensembl:ENSG00000110680(gene)|ensembl:ENST00000331587(transcript)|ensembl:ENST00000396372(transcript)|go:"GO:0001984"(artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007566"(embryo implantation)|go:"GO:0007631"(feeding behavior)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0009408"(response to heat)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0031716"(calcitonin receptor binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045986"(negative regulation of smooth muscle contraction)|go:"GO:0048265"(response to pain)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001693(Calcitonin-like)|interpro:IPR018360|interpro:IPR021116|interpro:IPR021117|interpro:IPR021118|mint:P01258|rcsb pdb:2JXZ|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|reactome:R-HSA-977225|refseq:XP_016873772.1|refseq:XP_016873773.1|mint:MINT-5204004(identity)	-	-	-	figure legend:F2B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/10/01	2018/09/18	rogid:XAjzRea7vq4vsbCVKdZRYIWvfBM9606	rogid:LMHetYvCTJzVQ6Gu2beLPywSwtg9606	intact-crc:C7C0817B0D85AC03|rigid:C0c9+KYl5H5nyzvljTp0DLvx/s4	false	binding-associated region:428-651(MINT-5204024)|flag tag:?-?(MINT-5204022)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0072"(monoclonal antibody western blot)
uniprotkb:P01258	uniprotkb:Q01814	intact:EBI-1018474|uniprotkb:Q13935|uniprotkb:Q13937|uniprotkb:Q52LX7|uniprotkb:B7ZL39|ensembl:ENSP00000331746|ensembl:ENSP00000379657	intact:EBI-1174243|uniprotkb:O00766|uniprotkb:Q12994|uniprotkb:Q16818|ensembl:ENSP00000353414|ensembl:ENSP00000494716	psi-mi:calc_human(display_long)|uniprotkb:CALCA(gene name)|psi-mi:CALCA(display_short)|uniprotkb:CALC1(gene name synonym)	psi-mi:at2b2_human(display_long)|uniprotkb:ATP2B2(gene name)|psi-mi:ATP2B2(display_short)|uniprotkb:PMCA2(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 2(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Holton et al. (2007)	pubmed:17689535|imex:IM-10991|mint:MINT-5220120	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7542860|mint:MINT-5204027|imex:IM-10991-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001029124.1|refseq:NP_001732.1|ensembl:ENSG00000110680(gene)|ensembl:ENST00000331587(transcript)|ensembl:ENST00000396372(transcript)|go:"GO:0001984"(artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007566"(embryo implantation)|go:"GO:0007631"(feeding behavior)|go:"GO:0007568"(aging)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0009408"(response to heat)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0031716"(calcitonin receptor binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045986"(negative regulation of smooth muscle contraction)|go:"GO:0048265"(response to pain)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001693(Calcitonin-like)|interpro:IPR018360|interpro:IPR021116|interpro:IPR021117|interpro:IPR021118|mint:P01258|rcsb pdb:2JXZ|reactome:R-HSA-418555|reactome:R-HSA-419812|reactome:R-HSA-9660821|reactome:R-HSA-977225|refseq:XP_016873772.1|refseq:XP_016873773.1|mint:MINT-5204028(identity)	refseq:NP_001001331.1|refseq:XP_005265236.1|refseq:XP_011532054.1|refseq:XP_006713238.1|ensembl:ENSG00000157087(gene)|ensembl:ENST00000360273(transcript)|ensembl:ENST00000645850(transcript)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1905059"(P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030322|interpro:IPR036412|interpro:IPR044492|mint:Q01814|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_001317540.1|refseq:XP_016861970.1|refseq:XP_016861971.1|refseq:XP_016861972.1|refseq:XP_016861973.1|refseq:XP_016861975.1|refseq:XP_016861978.1|mint:MINT-5204031(identity)	-	-	-	figure legend:F2B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/10/01	2018/09/18	rogid:LMHetYvCTJzVQ6Gu2beLPywSwtg9606	rogid:bCD7j13UJUgWoSHShHLKJBiVGJM9606	intact-crc:172F3BE09B414C5B|rigid:7bZAtC6OGdyia5gXGufWAkwcsuw	false	-	flag tag:?-?(MINT-5204036)|binding-associated region:462-684(MINT-5204032)	-	-	psi-mi:"MI:0072"(monoclonal antibody western blot)	psi-mi:"MI:0705"(anti tag western blot)