#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P27694	uniprotkb:P03070	intact:EBI-621389|ensembl:ENSP00000254719|uniprotkb:Q59ES9|uniprotkb:A8K0Y9	intact:EBI-617698	psi-mi:rfa1_human(display_long)|uniprotkb:Replication factor A protein 1(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:RPA1(gene name)|psi-mi:RPA1(display_short)|uniprotkb:REPA1(gene name synonym)|uniprotkb:RPA70(gene name synonym)	psi-mi:lt_sv40(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Taneja et al. (2007)	pubmed:17673209|imex:IM-14006|mint:MINT-5222806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:1891767(sv40)|taxid:1891767(sv40)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7531802|mint:MINT-5222830|imex:IM-14006-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132383(gene)|ensembl:ENST00000254719(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016605"(PML body)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090734"(site of DNA damage)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|go:"GO:0006268"(DNA unwinding involved in DNA replication)|mint:P27694|rcsb pdb:1EWI|rcsb pdb:1FGU|rcsb pdb:1JMC|rcsb pdb:1L1O|rcsb pdb:2B29|rcsb pdb:2B3G|rcsb pdb:4IJH|rcsb pdb:4IJL|rcsb pdb:4IPC|rcsb pdb:4IPD|rcsb pdb:4IPG|rcsb pdb:4IPH|rcsb pdb:4LUO|rcsb pdb:4LUV|rcsb pdb:4LUZ|rcsb pdb:4LW1|rcsb pdb:4LWC|rcsb pdb:4NB3|rcsb pdb:4O0A|rcsb pdb:4R4C|rcsb pdb:4R4I|rcsb pdb:4R4O|rcsb pdb:4R4Q|rcsb pdb:4R4T|rcsb pdb:5E7N|rcsb pdb:5EAY|rcsb pdb:5N85|rcsb pdb:5N8A|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-3108214|refseq:NP_002936.1|dip:DIP-24189N|mint:MINT-5222832(identity)	go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0016787"(hydrolase activity)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039576"(suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR003133(T antigen, Ori-binding)|interpro:IPR010932(Large T antigen, polyomavirus,  C-terminus)|interpro:IPR016392(Large T antigen, polyomaviridae)|interpro:IPR017910|interpro:IPR027417|interpro:IPR036869|rcsb pdb:1EJL|rcsb pdb:1GH6|rcsb pdb:1N25|rcsb pdb:1Q1S|rcsb pdb:1Q1T|rcsb pdb:1SVL|rcsb pdb:1SVM|rcsb pdb:1SVO|rcsb pdb:1TBD|rcsb pdb:1Z1D|rcsb pdb:2FUF|rcsb pdb:2H1L|rcsb pdb:2IF9|rcsb pdb:2IPR|rcsb pdb:2ITJ|rcsb pdb:2ITL|rcsb pdb:2NL8|rcsb pdb:2NTC|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|rcsb pdb:2TBD|rcsb pdb:3QK2|rcsb pdb:3QN2|rcsb pdb:4E2I|rcsb pdb:4FGN|rcsb pdb:4GDF|rcsb pdb:4RXH|rcsb pdb:5D9I|refseq:YP_003708382.1|mint:P03070|dip:DIP-24251N|mint:MINT-5222831(identity)	-	-	-	figure legend:F1A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/19	2019/10/18	rogid:DRZpMUlGyS0Qa5XFEtx71k0iPig9606	rogid:IMcAp2PRxZXkbJ1eiXhJU9rD2JM1891767	intact-crc:4EFD3A415A97F4C5|rigid:lDmg6FohAnPsTm2rcot3niKZPkw	false	his tag:?-?(MINT-5223411)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P27694	uniprotkb:P49643	intact:EBI-621389|ensembl:ENSP00000254719|uniprotkb:Q59ES9|uniprotkb:A8K0Y9	intact:EBI-850004|uniprotkb:Q53FJ8|uniprotkb:Q6P1Q7|uniprotkb:Q8WVL2|uniprotkb:Q9H413|ensembl:ENSP00000484105	psi-mi:rfa1_human(display_long)|uniprotkb:Replication factor A protein 1(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:RPA1(gene name)|psi-mi:RPA1(display_short)|uniprotkb:REPA1(gene name synonym)|uniprotkb:RPA70(gene name synonym)	psi-mi:pri2_human(display_long)|uniprotkb:DNA primase 58 kDa subunit(gene name synonym)|uniprotkb:PRIM2(gene name)|psi-mi:PRIM2(display_short)|uniprotkb:PRIM2A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Taneja et al. (2007)	pubmed:17673209|imex:IM-14006|mint:MINT-5222806	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7531827|mint:MINT-5223474|imex:IM-14006-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000132383(gene)|ensembl:ENST00000254719(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016605"(PML body)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090734"(site of DNA damage)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|go:"GO:0006268"(DNA unwinding involved in DNA replication)|mint:P27694|rcsb pdb:1EWI|rcsb pdb:1FGU|rcsb pdb:1JMC|rcsb pdb:1L1O|rcsb pdb:2B29|rcsb pdb:2B3G|rcsb pdb:4IJH|rcsb pdb:4IJL|rcsb pdb:4IPC|rcsb pdb:4IPD|rcsb pdb:4IPG|rcsb pdb:4IPH|rcsb pdb:4LUO|rcsb pdb:4LUV|rcsb pdb:4LUZ|rcsb pdb:4LW1|rcsb pdb:4LWC|rcsb pdb:4NB3|rcsb pdb:4O0A|rcsb pdb:4R4C|rcsb pdb:4R4I|rcsb pdb:4R4O|rcsb pdb:4R4Q|rcsb pdb:4R4T|rcsb pdb:5E7N|rcsb pdb:5EAY|rcsb pdb:5N85|rcsb pdb:5N8A|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-3108214|refseq:NP_002936.1|dip:DIP-24189N|mint:MINT-5223476(identity)	refseq:NP_001269416.1|refseq:NP_001269417.1|refseq:NP_000938.2|dip:DIP-36438N|ensembl:ENSG00000146143(gene)|ensembl:ENST00000615550(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006269"(DNA replication, synthesis of RNA primer)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0071667"(DNA/RNA hybrid binding)|interpro:IPR007238(DNA primase, large subunit, eukaryotic/archaeal)|interpro:IPR016558(DNA primase, large subunit, eukaryotic)|mint:P49643|rcsb pdb:3L9Q|rcsb pdb:3Q36|rcsb pdb:4BPU|rcsb pdb:4BPW|rcsb pdb:4BPX|rcsb pdb:4RR2|rcsb pdb:5DQO|rcsb pdb:5EXR|rcsb pdb:5F0Q|rcsb pdb:5F0S|rcsb pdb:5I7M|rcsb pdb:6DHW|reactome:R-HSA-113501|reactome:R-HSA-174411|reactome:R-HSA-174430|reactome:R-HSA-68952|reactome:R-HSA-68962|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-9710421|mint:MINT-5223481(identity)	-	-	-	figure legend:F1B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/11/19	2014/10/16	rogid:DRZpMUlGyS0Qa5XFEtx71k0iPig9606	rogid:WL5i+CvK52C93/3X4a3MFQvD0JQ9606	intact-crc:AA7A907FA5FD0AAB|rigid:xE/rxrdLiGTd5UN8vUBm6d9GsP8	false	his tag:?-?(MINT-5223477)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)