#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P21731 uniprotkb:Q13162 intact:EBI-2625082|uniprotkb:O75228|uniprotkb:Q6DK52|uniprotkb:Q9UCY1|uniprotkb:Q9UCY2|ensembl:ENSP00000364336 intact:EBI-2211957|uniprotkb:Q6FHT3|ensembl:ENSP00000368646 psi-mi:ta2r_human(display_long)|uniprotkb:TBXA2R(gene name)|psi-mi:TBXA2R(display_short)|uniprotkb:Prostanoid TP receptor(gene name synonym) psi-mi:prdx4_human(display_long)|uniprotkb:PRDX4(gene name)|psi-mi:PRDX4(display_short)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym) psi-mi:"MI:0018"(two hybrid) Giguère et al. (2007) pubmed:17644091|imex:IM-10942|mint:MINT-5220101 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7507842|mint:MINT-4980980|imex:IM-10942-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011526516.1|refseq:NP_001051.1|refseq:NP_963998.2|ensembl:ENSG00000006638(gene)|ensembl:ENST00000375190(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007584"(response to nutrient)|go:"GO:0004961"(thromboxane A2 receptor activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0033574"(response to testosterone)|go:"GO:0042493"|go:"GO:0045471"(response to ethanol)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001105(Thromboxane receptor)|interpro:IPR008365(Prostanoid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P21731|rcsb pdb:1LBN|reactome:R-HSA-391908|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-428930|dip:DIP-41465N|mint:MINT-4980981(identity) refseq:NP_006397.1|ensembl:ENSG00000123131(gene)|ensembl:ENST00000379341(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:Q13162|rcsb pdb:2PN8|rcsb pdb:3TJB|rcsb pdb:3TJF|rcsb pdb:3TJG|rcsb pdb:3TJJ|rcsb pdb:3TJK|rcsb pdb:3TKP|rcsb pdb:3TKQ|rcsb pdb:3TKR|rcsb pdb:3TKS|rcsb pdb:4RQX|rcsb pdb:5HQP|reactome:R-HSA-6798695|mint:MINT-4980982(identity) - - - figure legend:NFA|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/09/11 2014/10/16 rogid:ee/bWzyKVAxt3HIuVZPQ4KNQKNs9606 rogid:5KWl3YuUpRDrSUxWlJS6sP7CLAs9606 intact-crc:A519193277DE40B0|rigid:ntFoHGAieJkntdYT1zC0YoefCA0 false tag:?-?(MINT-4980987) tag:?-?(MINT-4980993) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P21731 uniprotkb:Q13162 intact:EBI-2625082|uniprotkb:O75228|uniprotkb:Q6DK52|uniprotkb:Q9UCY1|uniprotkb:Q9UCY2|ensembl:ENSP00000364336 intact:EBI-2211957|uniprotkb:Q6FHT3|ensembl:ENSP00000368646 psi-mi:ta2r_human(display_long)|uniprotkb:TBXA2R(gene name)|psi-mi:TBXA2R(display_short)|uniprotkb:Prostanoid TP receptor(gene name synonym) psi-mi:prdx4_human(display_long)|uniprotkb:PRDX4(gene name)|psi-mi:PRDX4(display_short)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Giguère et al. (2007) pubmed:17644091|imex:IM-10942|mint:MINT-5220101 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7507900|mint:MINT-4980999|imex:IM-10942-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011526516.1|refseq:NP_001051.1|refseq:NP_963998.2|ensembl:ENSG00000006638(gene)|ensembl:ENST00000375190(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007584"(response to nutrient)|go:"GO:0004961"(thromboxane A2 receptor activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0033574"(response to testosterone)|go:"GO:0042493"|go:"GO:0045471"(response to ethanol)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001105(Thromboxane receptor)|interpro:IPR008365(Prostanoid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P21731|rcsb pdb:1LBN|reactome:R-HSA-391908|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-428930|dip:DIP-41465N|mint:MINT-4981000(identity) refseq:NP_006397.1|ensembl:ENSG00000123131(gene)|ensembl:ENST00000379341(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:Q13162|rcsb pdb:2PN8|rcsb pdb:3TJB|rcsb pdb:3TJF|rcsb pdb:3TJG|rcsb pdb:3TJJ|rcsb pdb:3TJK|rcsb pdb:3TKP|rcsb pdb:3TKQ|rcsb pdb:3TKR|rcsb pdb:3TKS|rcsb pdb:4RQX|rcsb pdb:5HQP|reactome:R-HSA-6798695|mint:MINT-4981006(identity) - - - figure legend:F1|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/09/11 2014/10/16 rogid:ee/bWzyKVAxt3HIuVZPQ4KNQKNs9606 rogid:5KWl3YuUpRDrSUxWlJS6sP7CLAs9606 intact-crc:9CFC81990E6B5CBF|rigid:ntFoHGAieJkntdYT1zC0YoefCA0 false ha tag:?-?(MINT-4981003) myc tag:?-?(MINT-4981009) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P21731 uniprotkb:Q13162 intact:EBI-2625082|uniprotkb:O75228|uniprotkb:Q6DK52|uniprotkb:Q9UCY1|uniprotkb:Q9UCY2|ensembl:ENSP00000364336 intact:EBI-2211957|uniprotkb:Q6FHT3|ensembl:ENSP00000368646 psi-mi:ta2r_human(display_long)|uniprotkb:TBXA2R(gene name)|psi-mi:TBXA2R(display_short)|uniprotkb:Prostanoid TP receptor(gene name synonym) psi-mi:prdx4_human(display_long)|uniprotkb:PRDX4(gene name)|psi-mi:PRDX4(display_short)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym) psi-mi:"MI:0096"(pull down) Giguère et al. (2007) pubmed:17644091|imex:IM-10942|mint:MINT-5220101 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7507968|mint:MINT-4981021|imex:IM-10942-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011526516.1|refseq:NP_001051.1|refseq:NP_963998.2|ensembl:ENSG00000006638(gene)|ensembl:ENST00000375190(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007584"(response to nutrient)|go:"GO:0004961"(thromboxane A2 receptor activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0033574"(response to testosterone)|go:"GO:0042493"|go:"GO:0045471"(response to ethanol)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001105(Thromboxane receptor)|interpro:IPR008365(Prostanoid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P21731|rcsb pdb:1LBN|reactome:R-HSA-391908|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-428930|dip:DIP-41465N|mint:MINT-4981022(identity) refseq:NP_006397.1|ensembl:ENSG00000123131(gene)|ensembl:ENST00000379341(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:Q13162|rcsb pdb:2PN8|rcsb pdb:3TJB|rcsb pdb:3TJF|rcsb pdb:3TJG|rcsb pdb:3TJJ|rcsb pdb:3TJK|rcsb pdb:3TKP|rcsb pdb:3TKQ|rcsb pdb:3TKR|rcsb pdb:3TKS|rcsb pdb:4RQX|rcsb pdb:5HQP|reactome:R-HSA-6798695|mint:MINT-4981028(identity) - - - figure legend:F2B|comment:"TF beta can interact through the following fragments with Prx4: 129-150, 217-244, 312-407"|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/11 2014/10/16 rogid:ee/bWzyKVAxt3HIuVZPQ4KNQKNs9606 rogid:5KWl3YuUpRDrSUxWlJS6sP7CLAs9606 intact-crc:C495284D612370A6|rigid:ntFoHGAieJkntdYT1zC0YoefCA0 false glutathione s tranferase tag:?-?(MINT-4981023) myc tag:?-?(MINT-4981029) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P27824 uniprotkb:Q13162 intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3 intact:EBI-2211957|uniprotkb:Q6FHT3|ensembl:ENSP00000368646 psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym) psi-mi:prdx4_human(display_long)|uniprotkb:PRDX4(gene name)|psi-mi:PRDX4(display_short)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Giguère et al. (2007) pubmed:17644091|imex:IM-10942|mint:MINT-5220101 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7508029|mint:MINT-4981047|imex:IM-10942-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N|mint:MINT-4981067(identity) refseq:NP_006397.1|ensembl:ENSG00000123131(gene)|ensembl:ENST00000379341(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:Q13162|rcsb pdb:2PN8|rcsb pdb:3TJB|rcsb pdb:3TJF|rcsb pdb:3TJG|rcsb pdb:3TJJ|rcsb pdb:3TJK|rcsb pdb:3TKP|rcsb pdb:3TKQ|rcsb pdb:3TKR|rcsb pdb:3TKS|rcsb pdb:4RQX|rcsb pdb:5HQP|reactome:R-HSA-6798695|mint:MINT-4981053(identity) go:"GO:0005783"(endoplasmic reticulum) - - figure legend:F5|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/09/11 2014/10/16 rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606 rogid:5KWl3YuUpRDrSUxWlJS6sP7CLAs9606 intact-crc:964F8A72EFC2E7AA|rigid:XVZcAboZ2OHQEI8YeOByliwZ6+c false - myc tag:?-?(MINT-4981055) - - psi-mi:"MI:0709"(polyclonal antibody immunostaining) psi-mi:"MI:0707"(anti tag immunostaining) uniprotkb:P27824 uniprotkb:P21731 intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3 intact:EBI-2625082|uniprotkb:O75228|uniprotkb:Q6DK52|uniprotkb:Q9UCY1|uniprotkb:Q9UCY2|ensembl:ENSP00000364336 psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym) psi-mi:ta2r_human(display_long)|uniprotkb:TBXA2R(gene name)|psi-mi:TBXA2R(display_short)|uniprotkb:Prostanoid TP receptor(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Giguère et al. (2007) pubmed:17644091|imex:IM-10942|mint:MINT-5220101 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7508029|mint:MINT-4981047|imex:IM-10942-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N|mint:MINT-4981067(identity) refseq:XP_011526516.1|refseq:NP_001051.1|refseq:NP_963998.2|ensembl:ENSG00000006638(gene)|ensembl:ENST00000375190(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007584"(response to nutrient)|go:"GO:0004961"(thromboxane A2 receptor activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0033574"(response to testosterone)|go:"GO:0042493"|go:"GO:0045471"(response to ethanol)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR001105(Thromboxane receptor)|interpro:IPR008365(Prostanoid receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:P21731|rcsb pdb:1LBN|reactome:R-HSA-391908|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-428930|dip:DIP-41465N|mint:MINT-4981048(identity) go:"GO:0005783"(endoplasmic reticulum) - - figure legend:F5|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/09/11 2014/10/16 rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606 rogid:ee/bWzyKVAxt3HIuVZPQ4KNQKNs9606 intact-crc:964F8A72EFC2E7AA|rigid:XVZcAboZ2OHQEI8YeOByliwZ6+c false - green fluorescent protein tag:?-?(MINT-4981049) - - psi-mi:"MI:0709"(polyclonal antibody immunostaining) psi-mi:"MI:0396"(predetermined participant)