#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P10276 uniprotkb:Q15788 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 intact:EBI-455189|uniprotkb:O00150|uniprotkb:O43792|uniprotkb:O43793|uniprotkb:Q13071|uniprotkb:Q13420|uniprotkb:Q2T9G5|uniprotkb:Q53SX3|uniprotkb:Q6GVI5|uniprotkb:Q7KYV3|ensembl:ENSP00000320940|ensembl:ENSP00000385216 psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:ncoa1_human(display_long)|uniprotkb:Steroid receptor coactivator 1(gene name synonym)|uniprotkb:RIP160(gene name synonym)|uniprotkb:Protein Hin-2(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-52(gene name synonym)|uniprotkb:NCOA1(gene name)|psi-mi:NCOA1(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:BHLHE74(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 74(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7505413|mint:MINT-5209864|imex:IM-11094-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|mint:MINT-5209865(identity) refseq:NP_671756.1|refseq:NP_671766.1|refseq:NP_003734.3|ensembl:ENSP00000379197|ensembl:ENST00000405141|ensembl:ENSP00000385097|ensembl:ENSP00000385216|ensembl:ENSP00000320940|ensembl:ENST00000395856|ensembl:ENST00000288599|ensembl:ENSP00000288599|refseq:XP_005264682.1|refseq:XP_005264683.1|refseq:XP_005264685.1|refseq:XP_016860657.1|refseq:XP_016860658.1|dip:DIP-30877N|ensembl:ENSG00000084676(gene)|ensembl:ENST00000348332(transcript)|ensembl:ENST00000406961(transcript)|go:"GO:0000435"(positive regulation of transcription from RNA polymerase II promoter by galactose)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002155"(regulation of thyroid hormone mediated signaling pathway)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007595"(lactation)|go:"GO:0008584"(male gonad development)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0060179"(male mating behavior)|go:"GO:0060713"(labyrinthine layer morphogenesis)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2001038"(regulation of cellular response to drug)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|rcsb pdb:2NV7|rcsb pdb:2P54|rcsb pdb:2PRG|rcsb pdb:3BEJ|rcsb pdb:3BQD|rcsb pdb:3CTB|rcsb pdb:3CWD|rcsb pdb:3DCT|rcsb pdb:3DCU|rcsb pdb:3DR1|rcsb pdb:3ET1|rcsb pdb:3ET3|rcsb pdb:3FEI|rcsb pdb:3FEJ|rcsb pdb:3FUR|rcsb pdb:3FXV|rcsb pdb:3G8I|rcsb pdb:3G9E|rcsb pdb:3GYT|rcsb pdb:3GYU|rcsb pdb:3H0A|rcsb pdb:3HC5|rcsb pdb:3HC6|rcsb pdb:3HVL|rcsb pdb:3IPQ|rcsb pdb:3IPS|rcsb pdb:3IPU|rcsb pdb:3KMR|rcsb pdb:3LMP|rcsb pdb:3OKH|rcsb pdb:3OKI|rcsb pdb:3OLF|rcsb pdb:3OLL|rcsb pdb:3OLS|rcsb pdb:3OMK|rcsb pdb:3OMM|rcsb pdb:3OMO|rcsb pdb:3OMP|rcsb pdb:3OMQ|rcsb pdb:3OOF|rcsb pdb:3OOK|rcsb pdb:3P88|rcsb pdb:3P89|rcsb pdb:3QT0|rcsb pdb:3RUT|rcsb pdb:3RUU|rcsb pdb:3RVF|rcsb pdb:3S9S|rcsb pdb:3T03|rcsb pdb:3UU7|rcsb pdb:3UUA|rcsb pdb:3UUD|rcsb pdb:3V9Y|rcsb pdb:3VN2|rcsb pdb:4DK7|rcsb pdb:4DK8|rcsb pdb:4DM6|rcsb pdb:4DM8|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028819|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q15788|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1K4W|rcsb pdb:1K74|rcsb pdb:1K7L|rcsb pdb:1KV6|rcsb pdb:1N4H|rcsb pdb:1NQ7|rcsb pdb:1NRL|rcsb pdb:1P8D|rcsb pdb:1PZL|rcsb pdb:1RDT|rcsb pdb:1TFC|rcsb pdb:1U3R|rcsb pdb:1U3S|rcsb pdb:1X76|rcsb pdb:1X78|rcsb pdb:1X7B|rcsb pdb:1X7J|rcsb pdb:1XIU|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YY4|rcsb pdb:1YYE|rcsb pdb:1ZAF|rcsb pdb:2A3I|rcsb pdb:2C52|rcsb pdb:2FVJ|rcsb pdb:2GTK|rcsb pdb:2HBH|rcsb pdb:2HC4|rcsb pdb:2HCD|rcsb pdb:2HFP|rcsb pdb:2NPA|rcsb pdb:5Q0J|rcsb pdb:5Q0K|rcsb pdb:5Q0L|rcsb pdb:5Q0M|rcsb pdb:5Q0N|rcsb pdb:5Q0O|rcsb pdb:5Q0P|rcsb pdb:5Q0Q|rcsb pdb:5Q0R|rcsb pdb:5Q0S|rcsb pdb:5Q0T|rcsb pdb:5Q0U|rcsb pdb:5Q0V|rcsb pdb:5Q0W|rcsb pdb:5Q0X|rcsb pdb:5Q0Y|rcsb pdb:5Q0Z|rcsb pdb:5Q10|rcsb pdb:5Q11|rcsb pdb:5Q12|rcsb pdb:5Q13|rcsb pdb:5Q14|rcsb pdb:5Q15|rcsb pdb:5Q16|rcsb pdb:5Q18|rcsb pdb:5Q19|rcsb pdb:5Q1A|rcsb pdb:5Q1B|rcsb pdb:5Q1C|rcsb pdb:5DV6|rcsb pdb:5DV8|rcsb pdb:5DVC|rcsb pdb:5DWL|rcsb pdb:5E7V|rcsb pdb:5GTN|rcsb pdb:5GTO|rcsb pdb:5GTP|rcsb pdb:5HJS|rcsb pdb:5JI0|rcsb pdb:5JMM|rcsb pdb:5L7E|rcsb pdb:5L7G|rcsb pdb:5L7H|rcsb pdb:5MWP|rcsb pdb:5MWY|rcsb pdb:5MX7|rcsb pdb:5NKY|rcsb pdb:5NMA|rcsb pdb:5NMB|rcsb pdb:5NWM|rcsb pdb:5OW7|rcsb pdb:5OW9|rcsb pdb:5OWD|rcsb pdb:4G1Z|rcsb pdb:4G20|rcsb pdb:4G21|rcsb pdb:4G2H|rcsb pdb:4HEE|rcsb pdb:4J5X|rcsb pdb:4JYG|rcsb pdb:4JYH|rcsb pdb:4JYI|rcsb pdb:4MG5|rcsb pdb:4MG6|rcsb pdb:4MG7|rcsb pdb:4DQM|rcsb pdb:4MG8|rcsb pdb:4MG9|rcsb pdb:4MGA|rcsb pdb:4MGB|rcsb pdb:4MGC|rcsb pdb:4MGD|rcsb pdb:4RUJ|rcsb pdb:4RUP|rcsb pdb:4TUZ|rcsb pdb:4TV1|rcsb pdb:4UDA|rcsb pdb:4UDB|rcsb pdb:4Y29|rcsb pdb:5A86|rcsb pdb:5AVI|rcsb pdb:5AVL|rcsb pdb:4F9M|rcsb pdb:4FGY|rcsb pdb:4G1D|rcsb pdb:4G1Y|rcsb pdb:5AZT|rcsb pdb:5DSH|rcsb pdb:5DV3|rcsb pdb:6L96|rcsb pdb:6NX1|rcsb pdb:6P9F|rcsb pdb:6SSQ|rcsb pdb:6T2M|rcsb pdb:6TFI|rcsb pdb:6U25|rcsb pdb:6W9H|rcsb pdb:6W9I|rcsb pdb:6XP9|rcsb pdb:7BPY|rcsb pdb:7BPZ|rcsb pdb:7BQ0|rcsb pdb:7BQ1|rcsb pdb:7BQ2|rcsb pdb:7BQ3|rcsb pdb:7BQ4|rcsb pdb:7JYM|rcsb pdb:7KXD|rcsb pdb:7KXE|rcsb pdb:7KXF|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-1989781|reactome:R-HSA-211976|reactome:R-HSA-193807|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214847|reactome:R-HSA-381340|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6BNS|rcsb pdb:6E3G|rcsb pdb:6FO7|rcsb pdb:6FO8|rcsb pdb:6FO9|rcsb pdb:6FOB|rcsb pdb:6FOD|rcsb pdb:6GEV|rcsb pdb:6GG8|rcsb pdb:5Q1D|rcsb pdb:6HTY|rcsb pdb:6ICJ|rcsb pdb:5Q1E|rcsb pdb:6IJR|rcsb pdb:6IJS|rcsb pdb:6ILQ|rcsb pdb:6ITM|rcsb pdb:6JNR|rcsb pdb:6JQ7|rcsb pdb:5Q1F|rcsb pdb:5Q1G|rcsb pdb:5Q1H|rcsb pdb:5Q1I|rcsb pdb:5X0R|rcsb pdb:5X8U|rcsb pdb:5X8W|rcsb pdb:5Y44|rcsb pdb:5YCN|rcsb pdb:5YCP|rcsb pdb:5YP6|rcsb pdb:6A5W|rcsb pdb:6A5X|rcsb pdb:6A5Y|rcsb pdb:6KTM|rcsb pdb:6KTN|rcsb pdb:6L6K|interpro:IPR011598(Helix-loop-helix DNA-binding)|mint:MINT-5209866(identity) - - - figure legend:F1B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 rogid:OKjGLyCEDCW1kgUe6qB9bnKO4Rs9606 intact-crc:432C4DEC85A5CFDC|rigid:VAya5kpJqPVu9we7YVD/0hP4K08 false tag:?-?(MINT-5209870)|binding-associated region:212-403(MINT-5209873) binding-associated region:1205-1441(MINT-5209879)|tag:?-?(MINT-5209876) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10276 uniprotkb:Q71SY5 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7505457|mint:MINT-5209882|imex:IM-11094-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|mint:MINT-5209883(identity) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5209889(identity) - - - figure legend:F1B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 intact-crc:182B1F7AF44EDC5A|rigid:nBM0ym809y28TH0XEpcp7U8usRQ false binding-associated region:212-403(MINT-5209884)|tag:?-?(MINT-5209886) binding-associated region:564-747(MINT-5209890)|tag:?-?(MINT-5209892) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10276 uniprotkb:Q15648 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651 psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7505544|mint:MINT-5209905|imex:IM-11094-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|mint:MINT-5209906(identity) refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N|mint:MINT-5209912(identity) - - - figure legend:F1B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606 intact-crc:BDBC5D59389961BD|rigid:SDJ+TVwFjttr12V7/RpIUWAnwiQ false binding-associated region:212-403(MINT-5209909)|tag:?-?(MINT-5209907) tag:?-?(MINT-5209913)|binding-associated region:550-1581(MINT-5209915) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P48552 uniprotkb:P10276 intact:EBI-746484|uniprotkb:Q8IWE8|ensembl:ENSP00000327213|ensembl:ENSP00000383060|ensembl:ENSP00000383063 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 psi-mi:nrip1_human(display_long)|uniprotkb:Nuclear factor RIP140(gene name synonym)|uniprotkb:Receptor-interacting protein 140(gene name synonym)|uniprotkb:NRIP1(gene name)|psi-mi:NRIP1(display_short) psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7505595|mint:MINT-5209920|imex:IM-11094-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011528049.1|refseq:XP_011528050.1|refseq:XP_011528051.1|refseq:XP_011528053.1|refseq:XP_011528054.1|refseq:NP_003480.2|ensembl:ENSG00000180530(gene)|ensembl:ENST00000318948(transcript)|ensembl:ENST00000400199(transcript)|ensembl:ENST00000400202(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001543"(ovarian follicle rupture)|go:"GO:0001650"(fibrillar center)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR026649|interpro:IPR031405|interpro:IPR031406|interpro:IPR031407|interpro:IPR031408|mint:P48552|rcsb pdb:2GPO|rcsb pdb:2GPP|rcsb pdb:4S14|rcsb pdb:4S15|rcsb pdb:5NTI|rcsb pdb:5NTN|rcsb pdb:5NTW|rcsb pdb:5NU1|rcsb pdb:6FZU|rcsb pdb:6G05|rcsb pdb:6G07|reactome:R-HSA-3899300|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9029558|reactome:R-HSA-9632974|go:"GO:0019915"(lipid storage)|reactome:R-HSA-9707616|refseq:XP_005261120.1|refseq:XP_005261122.1|refseq:XP_016883962.1|refseq:XP_016883963.1|refseq:XP_016883964.1|refseq:XP_016883965.1|dip:DIP-5964N|mint:MINT-5209927(identity) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|mint:MINT-5209921(identity) - - - figure legend:NFA|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:Vo0KQPaqN9cxxqSDed0v7V94Dd09606 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 intact-crc:3BF1A08A8D026820|rigid:ddsHr5jvgkbAJUWbKX9hdAsl7/k false tag:?-?(MINT-5209930) tag:?-?(MINT-5209924)|binding-associated region:?-?(MINT-5209922) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q71SY5 uniprotkb:P10276 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7505618|mint:MINT-5209938|imex:IM-11094-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5209945(identity) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|mint:MINT-5209939(identity) - - - figure legend:NFA|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 intact-crc:52B2ABD335750371|rigid:nBM0ym809y28TH0XEpcp7U8usRQ false tag:?-?(MINT-5209946) tag:?-?(MINT-5209940)|binding-associated region:?-?(MINT-5209942) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10276 uniprotkb:Q71SY5 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7505679|mint:MINT-5209983|imex:IM-11094-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|mint:MINT-5209984(identity) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5209990(identity) - - - figure legend:F1C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 intact-crc:49C718B722CFADAE|rigid:nBM0ym809y28TH0XEpcp7U8usRQ false tag:?-?(MINT-5209985) tag:?-?(MINT-5209991) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q12796 uniprotkb:P10276 intact:EBI-2827376|uniprotkb:Q5T7J6|uniprotkb:B2R6Q0|ensembl:ENSP00000336931|uniprotkb:E1P515|uniprotkb:Q7Z5N0 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 psi-mi:pnrc1_human(display_long)|uniprotkb:PROL2(gene name synonym)|uniprotkb:Proline-rich protein 2(gene name synonym)|uniprotkb:Protein B4-2(gene name synonym)|uniprotkb:PNRC1(gene name)|psi-mi:PNRC1(display_short) psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7505641|mint:MINT-5209956|imex:IM-11094-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006804.1|ensembl:ENSG00000146278(gene)|go:"GO:0005634"(nucleus)|interpro:IPR026780|mint:Q12796|ensembl:ENST00000336032(transcript)|mint:MINT-5209963(identity) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|mint:MINT-5209957(identity) - - - figure legend:NFA|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:UltK56rTgcGIPUzX8WvV66EBD0U9606 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 intact-crc:43BCF41E92049F8C|rigid:MpAYPCQAodSJTewlMHaW6/EKvno false tag:?-?(MINT-5209964) tag:?-?(MINT-5209960)|binding-associated region:?-?(MINT-5209958) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10828 uniprotkb:Q71SY5 intact:EBI-78558|uniprotkb:P37243|uniprotkb:Q6WGL2|intact:EBI-452738|uniprotkb:Q13986|uniprotkb:Q3KP35|uniprotkb:B3KU79|uniprotkb:Q9UD41|ensembl:ENSP00000348827|ensembl:ENSP00000379904|ensembl:ENSP00000414444|ensembl:ENSP00000493709|ensembl:ENSP00000494618|ensembl:ENSP00000496029|ensembl:ENSP00000496509|ensembl:ENSP00000496616|ensembl:ENSP00000496686 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 psi-mi:thb_human(display_long)|uniprotkb:THRB(gene name)|psi-mi:THRB(display_short)|uniprotkb:c-erbA-beta(gene name synonym)|uniprotkb:c-erbA-2(gene name synonym)|uniprotkb:ERBA2(gene name synonym)|uniprotkb:NR1A2(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group A member 2(gene name synonym)|uniprotkb:THR1(gene name synonym) psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7505760|mint:MINT-5210013|imex:IM-11094-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011532348.1|refseq:XP_011532349.1|refseq:XP_011532350.1|refseq:NP_000452.2|refseq:NP_001121648.1|refseq:NP_001121649.1|refseq:XP_011532351.1|refseq:XP_011532352.1|refseq:XP_011532353.1|refseq:XP_011532354.1|refseq:NP_001239563.1|refseq:XP_006713380.1|refseq:XP_006713381.1|refseq:XP_005265478.1|refseq:XP_005265480.1|refseq:XP_005265481.1|refseq:XP_016862597.1|refseq:XP_016862598.1|refseq:XP_016862599.1|refseq:XP_016862600.1|refseq:XP_016862601.1|dip:DIP-5991N|ensembl:ENSG00000151090(gene)|ensembl:ENST00000356447(transcript)|ensembl:ENST00000396671(transcript)|ensembl:ENST00000416420(transcript)|ensembl:ENST00000642307(transcript)|ensembl:ENST00000643772(transcript)|ensembl:ENST00000644321(transcript)|ensembl:ENST00000645139(transcript)|ensembl:ENST00000646209(transcript)|ensembl:ENST00000646432(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007621"(negative regulation of female receptivity)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008050"(female courtship behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0097474"(retinal cone cell apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR001728(Thyroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10828|rcsb pdb:1BSX|rcsb pdb:1N46|rcsb pdb:1NAX|rcsb pdb:1NQ0|rcsb pdb:1NQ1|rcsb pdb:1NQ2|rcsb pdb:1NUO|rcsb pdb:1Q4X|rcsb pdb:1R6G|rcsb pdb:1XZX|rcsb pdb:1Y0X|rcsb pdb:2J4A|rcsb pdb:2NLL|rcsb pdb:2PIN|rcsb pdb:3D57|rcsb pdb:3GWS|rcsb pdb:3IMY|rcsb pdb:3JZC|rcsb pdb:4ZO1|rcsb pdb:6KKB|rcsb pdb:6KKE|rcsb pdb:6KNU|rcsb pdb:6KNV|rcsb pdb:6KNW|reactome:R-HSA-383280|reactome:R-HSA-4090294|mint:MINT-5210018(identity) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5210014(identity) - - - figure legend:F1C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:dR9VjMLXkNcIOL2a//S9CsBJHVE9606 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 intact-crc:33096955B798C2AE|rigid:hLAL2f7UFYs0jTvfHlGyuQsujwQ false tag:?-?(MINT-5210019) tag:?-?(MINT-5210015) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q71SY5 uniprotkb:P19793 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 intact:EBI-78598|uniprotkb:Q2V504|uniprotkb:B3KY83|uniprotkb:Q2NL52|ensembl:ENSP00000419692 psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:rxra_human(display_long)|uniprotkb:RXRA(gene name)|psi-mi:RXRA(display_short)|uniprotkb:NR2B1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7505724|mint:MINT-5210002|imex:IM-11094-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5210007(identity) refseq:NP_002948.1|refseq:NP_001278850.1|dip:DIP-641N|ensembl:ENSG00000186350(gene)|ensembl:ENST00000481739(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P19793|rcsb pdb:1BY4|rcsb pdb:1DSZ|rcsb pdb:1FBY|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1G1U|rcsb pdb:1G5Y|rcsb pdb:1K74|rcsb pdb:1MV9|rcsb pdb:1MVC|rcsb pdb:1MZN|rcsb pdb:1R0N|rcsb pdb:1RDT|rcsb pdb:1RXR|rcsb pdb:1XLS|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YNW|rcsb pdb:2ACL|rcsb pdb:2NLL|rcsb pdb:2P1T|rcsb pdb:2P1U|rcsb pdb:2P1V|rcsb pdb:2ZXZ|rcsb pdb:2ZY0|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3E94|rcsb pdb:3FAL|rcsb pdb:3FC6|rcsb pdb:3FUG|rcsb pdb:3H0A|rcsb pdb:3KWY|rcsb pdb:3NSP|rcsb pdb:3NSQ|rcsb pdb:3OAP|rcsb pdb:3OZJ|rcsb pdb:3PCU|rcsb pdb:3R2A|rcsb pdb:3R5M|rcsb pdb:3UVV|rcsb pdb:4CN2|rcsb pdb:4CN3|rcsb pdb:4CN5|rcsb pdb:4CN7|rcsb pdb:4J5W|rcsb pdb:4J5X|rcsb pdb:4K4J|rcsb pdb:4K6I|rcsb pdb:4M8E|rcsb pdb:4M8H|rcsb pdb:4N5G|rcsb pdb:4N8R|rcsb pdb:4NQA|rcsb pdb:4OC7|rcsb pdb:4POH|rcsb pdb:4POJ|rcsb pdb:4PP3|rcsb pdb:4PP5|rcsb pdb:4RFW|rcsb pdb:4RMC|rcsb pdb:4RMD|rcsb pdb:4RME|rcsb pdb:4ZO1|rcsb pdb:4ZSH|rcsb pdb:5EC9|rcsb pdb:5JI0|rcsb pdb:5LYQ|rcsb pdb:5MJ5|rcsb pdb:5MK4|rcsb pdb:5MKJ|rcsb pdb:5MKU|rcsb pdb:5MMW|rcsb pdb:5TBP|rcsb pdb:5UAN|rcsb pdb:5Z12|rcsb pdb:5ZQU|rcsb pdb:6A5Y|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6FBQ|rcsb pdb:6FBR|rcsb pdb:6HN6|rcsb pdb:6JNO|rcsb pdb:6JNR|rcsb pdb:6L6K|rcsb pdb:6LB4|rcsb pdb:6LB5|rcsb pdb:6LB6|rcsb pdb:6SJM|rcsb pdb:6STI|rcsb pdb:6XWG|rcsb pdb:6XWH|rcsb pdb:7A77|rcsb pdb:7B88|rcsb pdb:7B9O|rcsb pdb:7CFO|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-200425|reactome:R-HSA-204174|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9616222|reactome:R-HSA-9623433|reactome:R-HSA-9632974|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:3R29|mint:MINT-5210003(identity) - - - figure legend:F1C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 rogid:gKnKFur3dYudXOAePzqRZJxqzYQ9606 intact-crc:645E55F0EDA5E93A|rigid:Lqv7vUgJqYuV/ZDwQaecj4FWO3w false tag:?-?(MINT-5210008) tag:?-?(MINT-5210004) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9H2M2 uniprotkb:Q71SY5 intact:EBI-7505799|ensembl:ENSP00000415934|intact:MINT-4791372 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 psi-mi:q9h2m2_human(display_long)|uniprotkb:ESR1(gene name)|psi-mi:ESR1(display_short) psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7505811|mint:MINT-5210035|imex:IM-11094-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000091831(gene)|ensembl:ENST00000456483(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030284"(estrogen receptor activity)|interpro:IPR001292(Oestrogen receptor, AF1 modulatory)|mint:Q9H2M2|mint:MINT-5210040(identity) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5210036(identity) - comment:mint - figure legend:F1C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:2YxkzUs5DrCabuyBUWmPr5dO1lw9606 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 intact-crc:849CCD714F633296|rigid:dPgX2sP8+MoO5mCQSC7jFhjErxo false tag:?-?(MINT-5210041) tag:?-?(MINT-5210037) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04150 uniprotkb:Q71SY5 intact:EBI-493507|uniprotkb:P04151|uniprotkb:Q53EP5|uniprotkb:Q6N0A4|uniprotkb:B0LPG8|uniprotkb:D3DQF4|uniprotkb:A0ZXF9|uniprotkb:F5ATB7|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 psi-mi:gcr_human(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym) psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7505779|mint:MINT-5210024|imex:IM-11094-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000167.1|refseq:NP_001018084.1|refseq:NP_001018085.1|refseq:NP_001018086.1|refseq:NP_001018087.1|refseq:NP_001018661.1|refseq:NP_001019265.1|refseq:NP_001191187.1|refseq:NP_001191188.1|refseq:NP_001191189.1|refseq:NP_001191190.1|refseq:NP_001191191.1|refseq:NP_001191192.1|refseq:NP_001191193.1|refseq:XP_005268476.1|refseq:XP_005268477.1|refseq:XP_005268479.1|refseq:XP_005268480.1|ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|rcsb pdb:5E69|rcsb pdb:5E6A|rcsb pdb:5E6B|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|rcsb pdb:5E6C|rcsb pdb:5E6D|go:"GO:0019901"(protein kinase binding)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P04150|rcsb pdb:1M2Z|rcsb pdb:1NHZ|rcsb pdb:1P93|rcsb pdb:3BQD|rcsb pdb:3CLD|rcsb pdb:3E7C|rcsb pdb:3H52|rcsb pdb:3K22|rcsb pdb:3K23|rcsb pdb:4CSJ|rcsb pdb:4HN5|rcsb pdb:4HN6|rcsb pdb:4LSJ|rcsb pdb:4MDD|rcsb pdb:4P6W|rcsb pdb:4P6X|rcsb pdb:4UDC|rcsb pdb:4UDD|rcsb pdb:5CBX|rcsb pdb:5CBY|rcsb pdb:5CBZ|rcsb pdb:5CC1|refseq:XP_016864886.1|refseq:XP_016864887.1|rcsb pdb:5EMC|rcsb pdb:5EMP|rcsb pdb:5EMQ|rcsb pdb:5G3J|rcsb pdb:5G5W|rcsb pdb:5NFP|rcsb pdb:5NFT|rcsb pdb:5UC3|rcsb pdb:5VA0|rcsb pdb:5VA7|rcsb pdb:6BQU|rcsb pdb:6CFN|rcsb pdb:6DXK|rcsb pdb:6EL6|rcsb pdb:6EL7|rcsb pdb:6EL9|rcsb pdb:6X6D|rcsb pdb:6X6E|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6YOS|reactome:R-HSA-3371497|reactome:R-HSA-383280|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-8849473|reactome:R-HSA-8939902|reactome:R-HSA-9615017|reactome:R-HSA-9679191|dip:DIP-576N|mint:MINT-5210029(identity) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5210025(identity) - - - figure legend:F1C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 intact-crc:93C1C05DB8707943|rigid:t32bmU/NvE1rjJxffHLyTGYSSTY false tag:?-?(MINT-5210030) tag:?-?(MINT-5210026) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q71SY5 uniprotkb:P10276 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7505850|mint:MINT-5210046|imex:IM-11094-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5210051(identity) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|mint:MINT-5210047(identity) - - - figure legend:F1D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 intact-crc:548FBE34A62AAE98|rigid:nBM0ym809y28TH0XEpcp7U8usRQ false tag:?-?(MINT-5210052) mutation disrupting interaction:414-414(MINT-5210064)|tag:?-?(MINT-5210048)|binding-associated region:212-403(MINT-5210059)|mutation disrupting interaction:413-413(MINT-5210061) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10276 uniprotkb:Q71SY5 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7505900|mint:MINT-5210070|imex:IM-11094-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|mint:MINT-5210071(identity) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5210084(identity) - - - figure legend:F1D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 intact-crc:B530465DC1E3E9C6|rigid:nBM0ym809y28TH0XEpcp7U8usRQ false tag:?-?(MINT-5210081)|binding-associated region:212-403(MINT-5210072)|mutation disrupting interaction:409-409(MINT-5210075)|mutation disrupting interaction:410-410(MINT-5210078) tag:?-?(MINT-5210085) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q71SY5 uniprotkb:P10276 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7505954|mint:MINT-5210090|imex:IM-11094-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5210104(identity) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|mint:MINT-5210091(identity) - - - figure legend:F1D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 intact-crc:5F76BE5ECCEAC2FE|rigid:nBM0ym809y28TH0XEpcp7U8usRQ false tag:?-?(MINT-5210105) binding-associated region:212-403(MINT-5210100)|mutation disrupting interaction:412-412(MINT-5210094)|mutation disrupting interaction:415-415(MINT-5210097)|tag:?-?(MINT-5210092) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q71SY5 uniprotkb:P28700 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 intact:EBI-346715|ensembl:ENSMUSP00000076491|ensembl:ENSMUSP00000133044 psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:rxra_mouse(display_long)|uniprotkb:Rxra(gene name)|psi-mi:Rxra(display_short)|uniprotkb:Nr2b1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7505988|mint:MINT-5210116|imex:IM-11094-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5210130(identity) refseq:NP_035435.1|ensembl:ENSMUSG00000015846(gene)|ensembl:ENSMUST00000077257(transcript)|ensembl:ENSMUST00000166775(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045994"(positive regulation of translational initiation by iron)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060485"(mesenchyme development)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0061032"(visceral serous pericardium development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P28700|rcsb pdb:1DKF|rcsb pdb:1XDK|rcsb pdb:3A9E|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-200425|reactome:R-MMU-204174|reactome:R-MMU-211976|reactome:R-MMU-381340|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-4090294|reactome:R-MMU-5362517|reactome:R-MMU-9029569|reactome:R-MMU-9616222|reactome:R-MMU-9623433|reactome:R-MMU-9707564|mint:MINT-5210117(identity) - - - figure legend:F1D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 rogid:AYPX54m7lVs5Ls6EzBlOC9GBNyI10090 intact-crc:3B9C5005AF0348AC|rigid:EQVIvJNYdYPQu1oQceuQOXA6InE false tag:?-?(MINT-5210131) mutation disrupting interaction:455-455(MINT-5210121)|binding-associated region:237-448(MINT-5210118)|tag:?-?(MINT-5210127)|mutation disrupting interaction:456-456(MINT-5210124) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q71SY5 uniprotkb:P28700 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 intact:EBI-346715|ensembl:ENSMUSP00000076491|ensembl:ENSMUSP00000133044 psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:rxra_mouse(display_long)|uniprotkb:Rxra(gene name)|psi-mi:Rxra(display_short)|uniprotkb:Nr2b1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7506054|mint:MINT-5210136|imex:IM-11094-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5210137(identity) refseq:NP_035435.1|ensembl:ENSMUSG00000015846(gene)|ensembl:ENSMUST00000077257(transcript)|ensembl:ENSMUST00000166775(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045994"(positive regulation of translational initiation by iron)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060485"(mesenchyme development)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0061032"(visceral serous pericardium development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P28700|rcsb pdb:1DKF|rcsb pdb:1XDK|rcsb pdb:3A9E|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-200425|reactome:R-MMU-204174|reactome:R-MMU-211976|reactome:R-MMU-381340|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-4090294|reactome:R-MMU-5362517|reactome:R-MMU-9029569|reactome:R-MMU-9616222|reactome:R-MMU-9623433|reactome:R-MMU-9707564|mint:MINT-5210141(identity) - - - figure legend:F1D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 rogid:AYPX54m7lVs5Ls6EzBlOC9GBNyI10090 intact-crc:7E6DA0C63444DE78|rigid:EQVIvJNYdYPQu1oQceuQOXA6InE false tag:?-?(MINT-5210138) mutation disrupting interaction:460-460(MINT-5210147)|mutation disrupting interaction:459-459(MINT-5210144)|binding-associated region:237-448(MINT-5210150)|tag:?-?(MINT-5210142) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q71SY5 uniprotkb:P28700 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 intact:EBI-346715|ensembl:ENSMUSP00000076491|ensembl:ENSMUSP00000133044 psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:rxra_mouse(display_long)|uniprotkb:Rxra(gene name)|psi-mi:Rxra(display_short)|uniprotkb:Nr2b1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7506088|mint:MINT-5210156|imex:IM-11094-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5210157(identity) refseq:NP_035435.1|ensembl:ENSMUSG00000015846(gene)|ensembl:ENSMUST00000077257(transcript)|ensembl:ENSMUST00000166775(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045994"(positive regulation of translational initiation by iron)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060485"(mesenchyme development)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0061032"(visceral serous pericardium development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P28700|rcsb pdb:1DKF|rcsb pdb:1XDK|rcsb pdb:3A9E|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-200425|reactome:R-MMU-204174|reactome:R-MMU-211976|reactome:R-MMU-381340|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-4090294|reactome:R-MMU-5362517|reactome:R-MMU-9029569|reactome:R-MMU-9616222|reactome:R-MMU-9623433|reactome:R-MMU-9707564|mint:MINT-5210161(identity) - - - figure legend:F1D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 rogid:AYPX54m7lVs5Ls6EzBlOC9GBNyI10090 intact-crc:C2F6423635B21C6B|rigid:EQVIvJNYdYPQu1oQceuQOXA6InE false tag:?-?(MINT-5210158) mutation decreasing interaction:461-461(MINT-5210168)|tag:?-?(MINT-5210171)|binding-associated region:237-448(MINT-5210162) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VCB2 uniprotkb:P10276 intact:EBI-5745175|uniprotkb:Q3UDX6|uniprotkb:Q3UFQ1|uniprotkb:Q6IR27|ensembl:ENSMUSP00000003049 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 psi-mi:med25_mouse(display_long)|uniprotkb:Med25(gene name)|psi-mi:Med25(display_short)|uniprotkb:Mediator complex subunit 25(gene name synonym) psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7506168|mint:MINT-5210225|imex:IM-11094-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001318137.1|refseq:NP_083641.1|refseq:NP_001318135.1|ensembl:ENSMUSG00000002968(gene)|ensembl:ENSMUST00000003049(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q8VCB2|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:MINT-5210230(identity) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|mint:MINT-5210226(identity) - - - figure legend:F1E|figure legend:F1F|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:GKK8314k94deUs3Rh3Vi6Ubpw+o10090 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 intact-crc:5630325FD4A8CE4E|rigid:RLqJHHSEKyGaH1vcolAhRvjdGvA false binding-associated region:516-528(MINT-5210231)|mutation disrupting interaction:521-521,522-522,518-518(MINT-5210245)|tag:?-?(MINT-5210233) tag:?-?(MINT-5210227) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q71SY5 uniprotkb:P10276 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7506200|mint:MINT-5210176|imex:IM-11094-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5210190(identity) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|mint:MINT-5210177(identity) - - - figure legend:F1E|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 intact-crc:FF09C572EE1C0675|rigid:nBM0ym809y28TH0XEpcp7U8usRQ false binding-associated region:564-731(MINT-5210196)|tag:?-?(MINT-5210191) tag:?-?(MINT-5210187) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q71SY5 uniprotkb:P10276 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7506246|mint:MINT-5210199|imex:IM-11094-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5210204(identity) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|mint:MINT-5210200(identity) - - - figure legend:F1E|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 intact-crc:823A925B5C0DD59A|rigid:nBM0ym809y28TH0XEpcp7U8usRQ false binding-associated region:564-653(MINT-5210205)|tag:?-?(MINT-5210207) tag:?-?(MINT-5210201) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P10276 uniprotkb:Q71SY5 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:"MI:0018"(two hybrid) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7506306|mint:MINT-5210212|imex:IM-11094-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|mint:MINT-5210213(identity) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5210217(identity) - - - figure legend:F1E|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2007/10/24 2014/10/16 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 intact-crc:1AAD8AC12CAD0F62|rigid:nBM0ym809y28TH0XEpcp7U8usRQ false tag:?-?(MINT-5210214) binding-associated region:640-747(MINT-5210220)|tag:?-?(MINT-5210218) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8VCB2 uniprotkb:P11416 intact:EBI-5745175|uniprotkb:Q3UDX6|uniprotkb:Q3UFQ1|uniprotkb:Q6IR27|ensembl:ENSMUSP00000003049 intact:EBI-346736|uniprotkb:P22603|ensembl:ENSMUSP00000069744|ensembl:ENSMUSP00000103098|ensembl:ENSMUSP00000103099|ensembl:ENSMUSP00000129791 psi-mi:med25_mouse(display_long)|uniprotkb:Med25(gene name)|psi-mi:Med25(display_short)|uniprotkb:Mediator complex subunit 25(gene name synonym) psi-mi:rara_mouse(display_long)|uniprotkb:Rara(gene name)|psi-mi:Rara(display_short)|uniprotkb:Nr1b1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7506356|mint:MINT-5210263|imex:IM-11094-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001318137.1|refseq:NP_083641.1|refseq:NP_001318135.1|ensembl:ENSMUSG00000002968(gene)|ensembl:ENSMUST00000003049(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q8VCB2|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:MINT-5210268(identity) refseq:NP_001169999.1|refseq:NP_001170773.1|refseq:NP_001170774.1|refseq:NP_033050.2|refseq:XP_006532655.1|refseq:XP_006532656.1|refseq:XP_017169842.1|dip:DIP-31480N|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060348"(bone development)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|go:"GO:0030852"(regulation of granulocyte differentiation)|ensembl:ENSMUSG00000037992(gene)|ensembl:ENSMUST00000068133(transcript)|ensembl:ENSMUST00000107474(transcript)|ensembl:ENSMUST00000107475(transcript)|ensembl:ENSMUST00000164748(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P11416|reactome:R-MMU-383280|reactome:R-MMU-4090294|reactome:R-MMU-5362517|reactome:R-MMU-9616222|mint:MINT-5210264(identity) - - - figure legend:F2B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2007/10/24 2014/10/16 rogid:GKK8314k94deUs3Rh3Vi6Ubpw+o10090 rogid:Au9WAaW0hYj2SCVF3NjQMw0rGOw10090 intact-crc:FEA0E6CE5BC3FEA2|rigid:tZT5obwSbkYUenH+lK+/rsji1rs false flag tag:?-?(MINT-5210276) green fluorescent protein tag:?-?(MINT-5210265) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8VCB2 uniprotkb:P28700 intact:EBI-5745175|uniprotkb:Q3UDX6|uniprotkb:Q3UFQ1|uniprotkb:Q6IR27|ensembl:ENSMUSP00000003049 intact:EBI-346715|ensembl:ENSMUSP00000076491|ensembl:ENSMUSP00000133044 psi-mi:med25_mouse(display_long)|uniprotkb:Med25(gene name)|psi-mi:Med25(display_short)|uniprotkb:Mediator complex subunit 25(gene name synonym) psi-mi:rxra_mouse(display_long)|uniprotkb:Rxra(gene name)|psi-mi:Rxra(display_short)|uniprotkb:Nr2b1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7506374|mint:MINT-5210285|imex:IM-11094-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001318137.1|refseq:NP_083641.1|refseq:NP_001318135.1|ensembl:ENSMUSG00000002968(gene)|ensembl:ENSMUST00000003049(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q8VCB2|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:MINT-5210290(identity) refseq:NP_035435.1|ensembl:ENSMUSG00000015846(gene)|ensembl:ENSMUST00000077257(transcript)|ensembl:ENSMUST00000166775(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045994"(positive regulation of translational initiation by iron)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060485"(mesenchyme development)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060687"(regulation of branching involved in prostate gland morphogenesis)|go:"GO:0060978"(angiogenesis involved in coronary vascular morphogenesis)|go:"GO:0061032"(visceral serous pericardium development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P28700|rcsb pdb:1DKF|rcsb pdb:1XDK|rcsb pdb:3A9E|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-200425|reactome:R-MMU-204174|reactome:R-MMU-211976|reactome:R-MMU-381340|reactome:R-MMU-383280|reactome:R-MMU-400206|reactome:R-MMU-4090294|reactome:R-MMU-5362517|reactome:R-MMU-9029569|reactome:R-MMU-9616222|reactome:R-MMU-9623433|reactome:R-MMU-9707564|mint:MINT-5210286(identity) - - - figure legend:F2B|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-nih_3t3)|taxid:10090(Mus musculus Swiss NIH 3t3 embryo fibroblast cells) - 2007/10/24 2014/10/16 rogid:GKK8314k94deUs3Rh3Vi6Ubpw+o10090 rogid:AYPX54m7lVs5Ls6EzBlOC9GBNyI10090 intact-crc:4A7A63484C6B49A4|rigid:s0F7445pKkjmmvO911EK41nKExk false flag tag:?-?(MINT-5210291) green fluorescent protein tag:?-?(MINT-5210287) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P10276 uniprotkb:Q71SY5 intact:EBI-413374|uniprotkb:P78456|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q96S41|uniprotkb:Q9NQS0|uniprotkb:B8Y636|ensembl:ENSP00000254066|ensembl:ENSP00000377649 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 psi-mi:rara_human(display_long)|uniprotkb:RARA(gene name)|psi-mi:RARA(display_short)|uniprotkb:NR1B1(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group B member 1(gene name synonym) psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:"MI:0096"(pull down) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7506423|mint:MINT-5210334|imex:IM-11094-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000955.1|refseq:NP_001019980.1|refseq:NP_001138773.1|refseq:XP_011523397.1|refseq:NP_001138774.1|refseq:XP_005257610.1|refseq:XP_005257611.1|ensembl:ENSG00000131759(gene)|ensembl:ENST00000254066(transcript)|ensembl:ENST00000394089(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001843"(neural tube closure)|go:"GO:0001889"(liver development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007281"(germ cell development)|go:"GO:0007565"(female pregnancy)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030850"(prostate gland development)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032736"(positive regulation of interleukin-13 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0032754"(positive regulation of interleukin-5 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0034097"(response to cytokine)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045630"(positive regulation of T-helper 2 cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0055012"(ventricular cardiac muscle cell differentiation)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060010"(Sertoli cell fate commitment)|go:"GO:0060173"(limb development)|go:"GO:0060324"(face development)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060534"(trachea cartilage development)|go:"GO:0061037"(negative regulation of cartilage development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR003078(Retinoic acid receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P10276|rcsb pdb:1DKF|rcsb pdb:1DSZ|rcsb pdb:3A9E|rcsb pdb:3KMR|rcsb pdb:3KMZ|rcsb pdb:4DQM|rcsb pdb:5K13|rcsb pdb:6XWG|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9616222|reactome:R-HSA-383280|dip:DIP-34N|mint:MINT-5210335(identity) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5210339(identity) - - - figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/10/24 2014/10/16 rogid:hxW9W0aqa3qEJT5ZilJdJ4b+gEo9606 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 intact-crc:9C5EC01214365159|rigid:nBM0ym809y28TH0XEpcp7U8usRQ false - glutathione s tranferase tag:?-?(MINT-5210342)|binding-associated region:564-747(MINT-5210340) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19793 uniprotkb:Q71SY5 intact:EBI-78598|uniprotkb:Q2V504|uniprotkb:B3KY83|uniprotkb:Q2NL52|ensembl:ENSP00000419692 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 psi-mi:rxra_human(display_long)|uniprotkb:RXRA(gene name)|psi-mi:RXRA(display_short)|uniprotkb:NR2B1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:"MI:0096"(pull down) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7506443|mint:MINT-5210351|imex:IM-11094-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002948.1|refseq:NP_001278850.1|dip:DIP-641N|ensembl:ENSG00000186350(gene)|ensembl:ENST00000481739(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P19793|rcsb pdb:1BY4|rcsb pdb:1DSZ|rcsb pdb:1FBY|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1G1U|rcsb pdb:1G5Y|rcsb pdb:1K74|rcsb pdb:1MV9|rcsb pdb:1MVC|rcsb pdb:1MZN|rcsb pdb:1R0N|rcsb pdb:1RDT|rcsb pdb:1RXR|rcsb pdb:1XLS|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YNW|rcsb pdb:2ACL|rcsb pdb:2NLL|rcsb pdb:2P1T|rcsb pdb:2P1U|rcsb pdb:2P1V|rcsb pdb:2ZXZ|rcsb pdb:2ZY0|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3E94|rcsb pdb:3FAL|rcsb pdb:3FC6|rcsb pdb:3FUG|rcsb pdb:3H0A|rcsb pdb:3KWY|rcsb pdb:3NSP|rcsb pdb:3NSQ|rcsb pdb:3OAP|rcsb pdb:3OZJ|rcsb pdb:3PCU|rcsb pdb:3R2A|rcsb pdb:3R5M|rcsb pdb:3UVV|rcsb pdb:4CN2|rcsb pdb:4CN3|rcsb pdb:4CN5|rcsb pdb:4CN7|rcsb pdb:4J5W|rcsb pdb:4J5X|rcsb pdb:4K4J|rcsb pdb:4K6I|rcsb pdb:4M8E|rcsb pdb:4M8H|rcsb pdb:4N5G|rcsb pdb:4N8R|rcsb pdb:4NQA|rcsb pdb:4OC7|rcsb pdb:4POH|rcsb pdb:4POJ|rcsb pdb:4PP3|rcsb pdb:4PP5|rcsb pdb:4RFW|rcsb pdb:4RMC|rcsb pdb:4RMD|rcsb pdb:4RME|rcsb pdb:4ZO1|rcsb pdb:4ZSH|rcsb pdb:5EC9|rcsb pdb:5JI0|rcsb pdb:5LYQ|rcsb pdb:5MJ5|rcsb pdb:5MK4|rcsb pdb:5MKJ|rcsb pdb:5MKU|rcsb pdb:5MMW|rcsb pdb:5TBP|rcsb pdb:5UAN|rcsb pdb:5Z12|rcsb pdb:5ZQU|rcsb pdb:6A5Y|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6FBQ|rcsb pdb:6FBR|rcsb pdb:6HN6|rcsb pdb:6JNO|rcsb pdb:6JNR|rcsb pdb:6L6K|rcsb pdb:6LB4|rcsb pdb:6LB5|rcsb pdb:6LB6|rcsb pdb:6SJM|rcsb pdb:6STI|rcsb pdb:6XWG|rcsb pdb:6XWH|rcsb pdb:7A77|rcsb pdb:7B88|rcsb pdb:7B9O|rcsb pdb:7CFO|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-200425|reactome:R-HSA-204174|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9616222|reactome:R-HSA-9623433|reactome:R-HSA-9632974|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:3R29|mint:MINT-5210352(identity) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5210354(identity) - - - figure legend:F2A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/10/24 2014/10/16 rogid:gKnKFur3dYudXOAePzqRZJxqzYQ9606 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 intact-crc:F7DC53665EBB776B|rigid:Lqv7vUgJqYuV/ZDwQaecj4FWO3w false - binding-associated region:564-747(MINT-5210357)|glutathione s tranferase tag:?-?(MINT-5210355) - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q71SY5 uniprotkb:P19793 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 intact:EBI-78598|uniprotkb:Q2V504|uniprotkb:B3KY83|uniprotkb:Q2NL52|ensembl:ENSP00000419692 psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:rxra_human(display_long)|uniprotkb:RXRA(gene name)|psi-mi:RXRA(display_short)|uniprotkb:NR2B1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7506475|mint:MINT-5210362|imex:IM-11094-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5210363(identity) refseq:NP_002948.1|refseq:NP_001278850.1|dip:DIP-641N|ensembl:ENSG00000186350(gene)|ensembl:ENST00000481739(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P19793|rcsb pdb:1BY4|rcsb pdb:1DSZ|rcsb pdb:1FBY|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1G1U|rcsb pdb:1G5Y|rcsb pdb:1K74|rcsb pdb:1MV9|rcsb pdb:1MVC|rcsb pdb:1MZN|rcsb pdb:1R0N|rcsb pdb:1RDT|rcsb pdb:1RXR|rcsb pdb:1XLS|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YNW|rcsb pdb:2ACL|rcsb pdb:2NLL|rcsb pdb:2P1T|rcsb pdb:2P1U|rcsb pdb:2P1V|rcsb pdb:2ZXZ|rcsb pdb:2ZY0|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3E94|rcsb pdb:3FAL|rcsb pdb:3FC6|rcsb pdb:3FUG|rcsb pdb:3H0A|rcsb pdb:3KWY|rcsb pdb:3NSP|rcsb pdb:3NSQ|rcsb pdb:3OAP|rcsb pdb:3OZJ|rcsb pdb:3PCU|rcsb pdb:3R2A|rcsb pdb:3R5M|rcsb pdb:3UVV|rcsb pdb:4CN2|rcsb pdb:4CN3|rcsb pdb:4CN5|rcsb pdb:4CN7|rcsb pdb:4J5W|rcsb pdb:4J5X|rcsb pdb:4K4J|rcsb pdb:4K6I|rcsb pdb:4M8E|rcsb pdb:4M8H|rcsb pdb:4N5G|rcsb pdb:4N8R|rcsb pdb:4NQA|rcsb pdb:4OC7|rcsb pdb:4POH|rcsb pdb:4POJ|rcsb pdb:4PP3|rcsb pdb:4PP5|rcsb pdb:4RFW|rcsb pdb:4RMC|rcsb pdb:4RMD|rcsb pdb:4RME|rcsb pdb:4ZO1|rcsb pdb:4ZSH|rcsb pdb:5EC9|rcsb pdb:5JI0|rcsb pdb:5LYQ|rcsb pdb:5MJ5|rcsb pdb:5MK4|rcsb pdb:5MKJ|rcsb pdb:5MKU|rcsb pdb:5MMW|rcsb pdb:5TBP|rcsb pdb:5UAN|rcsb pdb:5Z12|rcsb pdb:5ZQU|rcsb pdb:6A5Y|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6FBQ|rcsb pdb:6FBR|rcsb pdb:6HN6|rcsb pdb:6JNO|rcsb pdb:6JNR|rcsb pdb:6L6K|rcsb pdb:6LB4|rcsb pdb:6LB5|rcsb pdb:6LB6|rcsb pdb:6SJM|rcsb pdb:6STI|rcsb pdb:6XWG|rcsb pdb:6XWH|rcsb pdb:7A77|rcsb pdb:7B88|rcsb pdb:7B9O|rcsb pdb:7CFO|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-200425|reactome:R-HSA-204174|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9616222|reactome:R-HSA-9623433|reactome:R-HSA-9632974|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:3R29|mint:MINT-5210369(identity) - - - figure legend:F2C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2007/10/24 2014/10/16 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 rogid:gKnKFur3dYudXOAePzqRZJxqzYQ9606 intact-crc:BDD9934F5D3F5F54|rigid:Lqv7vUgJqYuV/ZDwQaecj4FWO3w false green fluorescent protein tag:?-?(MINT-5210366) flag tag:?-?(MINT-5210376) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q71SY5 uniprotkb:P19793 intact:EBI-394558|intact:EBI-1534904|intact:EBI-399654|uniprotkb:O95783|uniprotkb:Q6P143|uniprotkb:Q6QMH5|uniprotkb:Q707U4|uniprotkb:Q8TB55|uniprotkb:Q9HB34|uniprotkb:Q9H0L5|uniprotkb:A8K095|uniprotkb:B9TX30|ensembl:ENSP00000326767 intact:EBI-78598|uniprotkb:Q2V504|uniprotkb:B3KY83|uniprotkb:Q2NL52|ensembl:ENSP00000419692 psi-mi:med25_human(display_long)|uniprotkb:MED25(gene name)|psi-mi:MED25(display_short)|uniprotkb:ACID1(gene name synonym)|uniprotkb:ARC92(gene name synonym)|uniprotkb:PTOV2(gene name synonym)|uniprotkb:Mediator complex subunit 25(gene name synonym)|uniprotkb:Activator-recruited cofactor 92 kDa component(gene name synonym)|uniprotkb:Activator interaction domain-containing protein 1(gene name synonym)|uniprotkb:p78(gene name synonym)|uniprotkb:TCBAP0758(orf name) psi-mi:rxra_human(display_long)|uniprotkb:RXRA(gene name)|psi-mi:RXRA(display_short)|uniprotkb:NR2B1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7506554|mint:MINT-5210379|imex:IM-11094-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_112235.2|ensembl:ENSG00000104973(gene)|ensembl:ENST00000312865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q71SY5|rcsb pdb:2KY6|rcsb pdb:2L23|rcsb pdb:2L6U|rcsb pdb:2XNF|rcsb pdb:7EMF|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSP00000326767|ensembl:ENST00000538643|ensembl:ENSP00000437496|dip:DIP-31454N|mint:MINT-5210380(identity) refseq:NP_002948.1|refseq:NP_001278850.1|dip:DIP-641N|ensembl:ENSG00000186350(gene)|ensembl:ENST00000481739(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P19793|rcsb pdb:1BY4|rcsb pdb:1DSZ|rcsb pdb:1FBY|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1G1U|rcsb pdb:1G5Y|rcsb pdb:1K74|rcsb pdb:1MV9|rcsb pdb:1MVC|rcsb pdb:1MZN|rcsb pdb:1R0N|rcsb pdb:1RDT|rcsb pdb:1RXR|rcsb pdb:1XLS|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YNW|rcsb pdb:2ACL|rcsb pdb:2NLL|rcsb pdb:2P1T|rcsb pdb:2P1U|rcsb pdb:2P1V|rcsb pdb:2ZXZ|rcsb pdb:2ZY0|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3E94|rcsb pdb:3FAL|rcsb pdb:3FC6|rcsb pdb:3FUG|rcsb pdb:3H0A|rcsb pdb:3KWY|rcsb pdb:3NSP|rcsb pdb:3NSQ|rcsb pdb:3OAP|rcsb pdb:3OZJ|rcsb pdb:3PCU|rcsb pdb:3R2A|rcsb pdb:3R5M|rcsb pdb:3UVV|rcsb pdb:4CN2|rcsb pdb:4CN3|rcsb pdb:4CN5|rcsb pdb:4CN7|rcsb pdb:4J5W|rcsb pdb:4J5X|rcsb pdb:4K4J|rcsb pdb:4K6I|rcsb pdb:4M8E|rcsb pdb:4M8H|rcsb pdb:4N5G|rcsb pdb:4N8R|rcsb pdb:4NQA|rcsb pdb:4OC7|rcsb pdb:4POH|rcsb pdb:4POJ|rcsb pdb:4PP3|rcsb pdb:4PP5|rcsb pdb:4RFW|rcsb pdb:4RMC|rcsb pdb:4RMD|rcsb pdb:4RME|rcsb pdb:4ZO1|rcsb pdb:4ZSH|rcsb pdb:5EC9|rcsb pdb:5JI0|rcsb pdb:5LYQ|rcsb pdb:5MJ5|rcsb pdb:5MK4|rcsb pdb:5MKJ|rcsb pdb:5MKU|rcsb pdb:5MMW|rcsb pdb:5TBP|rcsb pdb:5UAN|rcsb pdb:5Z12|rcsb pdb:5ZQU|rcsb pdb:6A5Y|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6FBQ|rcsb pdb:6FBR|rcsb pdb:6HN6|rcsb pdb:6JNO|rcsb pdb:6JNR|rcsb pdb:6L6K|rcsb pdb:6LB4|rcsb pdb:6LB5|rcsb pdb:6LB6|rcsb pdb:6SJM|rcsb pdb:6STI|rcsb pdb:6XWG|rcsb pdb:6XWH|rcsb pdb:7A77|rcsb pdb:7B88|rcsb pdb:7B9O|rcsb pdb:7CFO|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-200425|reactome:R-HSA-204174|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9616222|reactome:R-HSA-9623433|reactome:R-HSA-9632974|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:3R29|mint:MINT-5210386(identity) - - - figure legend:F2E|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2007/10/24 2014/10/16 rogid:oh/gQ7Xo30kPBJDKME6QDW448Dg9606 rogid:gKnKFur3dYudXOAePzqRZJxqzYQ9606 intact-crc:3F739F1659848633|rigid:Lqv7vUgJqYuV/ZDwQaecj4FWO3w false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P19793 uniprotkb:Q8VCB2 intact:EBI-78598|uniprotkb:Q2V504|uniprotkb:B3KY83|uniprotkb:Q2NL52|ensembl:ENSP00000419692 intact:EBI-5745175|uniprotkb:Q3UDX6|uniprotkb:Q3UFQ1|uniprotkb:Q6IR27|ensembl:ENSMUSP00000003049 psi-mi:rxra_human(display_long)|uniprotkb:RXRA(gene name)|psi-mi:RXRA(display_short)|uniprotkb:NR2B1(gene name synonym)|uniprotkb:Retinoid X receptor alpha(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group B member 1(gene name synonym) psi-mi:med25_mouse(display_long)|uniprotkb:Med25(gene name)|psi-mi:Med25(display_short)|uniprotkb:Mediator complex subunit 25(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Lee et al. (2007) pubmed:17641689|imex:IM-11094|mint:MINT-5220098 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7506568|mint:MINT-5210397|imex:IM-11094-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002948.1|refseq:NP_001278850.1|dip:DIP-641N|ensembl:ENSG00000186350(gene)|ensembl:ENST00000481739(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050692"(DNA binding domain binding)|go:"GO:0050693"(LBD domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR021780|interpro:IPR035500|mint:P19793|rcsb pdb:1BY4|rcsb pdb:1DSZ|rcsb pdb:1FBY|rcsb pdb:1FM6|rcsb pdb:1FM9|rcsb pdb:1G1U|rcsb pdb:1G5Y|rcsb pdb:1K74|rcsb pdb:1MV9|rcsb pdb:1MVC|rcsb pdb:1MZN|rcsb pdb:1R0N|rcsb pdb:1RDT|rcsb pdb:1RXR|rcsb pdb:1XLS|rcsb pdb:1XV9|rcsb pdb:1XVP|rcsb pdb:1YNW|rcsb pdb:2ACL|rcsb pdb:2NLL|rcsb pdb:2P1T|rcsb pdb:2P1U|rcsb pdb:2P1V|rcsb pdb:2ZXZ|rcsb pdb:2ZY0|rcsb pdb:3DZU|rcsb pdb:3DZY|rcsb pdb:3E00|rcsb pdb:3E94|rcsb pdb:3FAL|rcsb pdb:3FC6|rcsb pdb:3FUG|rcsb pdb:3H0A|rcsb pdb:3KWY|rcsb pdb:3NSP|rcsb pdb:3NSQ|rcsb pdb:3OAP|rcsb pdb:3OZJ|rcsb pdb:3PCU|rcsb pdb:3R2A|rcsb pdb:3R5M|rcsb pdb:3UVV|rcsb pdb:4CN2|rcsb pdb:4CN3|rcsb pdb:4CN5|rcsb pdb:4CN7|rcsb pdb:4J5W|rcsb pdb:4J5X|rcsb pdb:4K4J|rcsb pdb:4K6I|rcsb pdb:4M8E|rcsb pdb:4M8H|rcsb pdb:4N5G|rcsb pdb:4N8R|rcsb pdb:4NQA|rcsb pdb:4OC7|rcsb pdb:4POH|rcsb pdb:4POJ|rcsb pdb:4PP3|rcsb pdb:4PP5|rcsb pdb:4RFW|rcsb pdb:4RMC|rcsb pdb:4RMD|rcsb pdb:4RME|rcsb pdb:4ZO1|rcsb pdb:4ZSH|rcsb pdb:5EC9|rcsb pdb:5JI0|rcsb pdb:5LYQ|rcsb pdb:5MJ5|rcsb pdb:5MK4|rcsb pdb:5MKJ|rcsb pdb:5MKU|rcsb pdb:5MMW|rcsb pdb:5TBP|rcsb pdb:5UAN|rcsb pdb:5Z12|rcsb pdb:5ZQU|rcsb pdb:6A5Y|rcsb pdb:6A5Z|rcsb pdb:6A60|rcsb pdb:6FBQ|rcsb pdb:6FBR|rcsb pdb:6HN6|rcsb pdb:6JNO|rcsb pdb:6JNR|rcsb pdb:6L6K|rcsb pdb:6LB4|rcsb pdb:6LB5|rcsb pdb:6LB6|rcsb pdb:6SJM|rcsb pdb:6STI|rcsb pdb:6XWG|rcsb pdb:6XWH|rcsb pdb:7A77|rcsb pdb:7B88|rcsb pdb:7B9O|rcsb pdb:7CFO|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-159418|reactome:R-HSA-192105|reactome:R-HSA-193368|reactome:R-HSA-193807|reactome:R-HSA-1989781|reactome:R-HSA-200425|reactome:R-HSA-204174|reactome:R-HSA-211976|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-4090294|reactome:R-HSA-5362517|reactome:R-HSA-5617472|reactome:R-HSA-9029558|reactome:R-HSA-9029569|reactome:R-HSA-9031525|reactome:R-HSA-9031528|reactome:R-HSA-9616222|reactome:R-HSA-9623433|reactome:R-HSA-9632974|reactome:R-HSA-9707564|reactome:R-HSA-9707616|rcsb pdb:3R29|mint:MINT-5210400(identity) refseq:NP_001318137.1|refseq:NP_083641.1|refseq:NP_001318135.1|ensembl:ENSMUSG00000002968(gene)|ensembl:ENSMUST00000003049(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0016592"(mediator complex)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2001178"(positive regulation of mediator complex assembly)|interpro:IPR021394|interpro:IPR021397|interpro:IPR021406|interpro:IPR021419|interpro:IPR036465|interpro:IPR038196|mint:Q8VCB2|rcsb pdb:6W1S|reactome:R-MMU-212436|mint:MINT-5210398(identity) - - - figure legend:F2E|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2007/10/24 2014/10/16 rogid:gKnKFur3dYudXOAePzqRZJxqzYQ9606 rogid:GKK8314k94deUs3Rh3Vi6Ubpw+o10090 intact-crc:E506765F343BD837|rigid:R82OYjv6xDxjqCO4yCW/fiqREKA false - flag tag:?-?(MINT-5210406)|mutation disrupting interaction:646-649(MINT-5210408) - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0705"(anti tag western blot)