#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P03070 uniprotkb:P04637 intact:EBI-617698 intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5 psi-mi:lt_sv40(display_long) psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:1891767(sv40)|taxid:1891767(sv40) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368391 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0016787"(hydrolase activity)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039576"(suppression by virus of host JAK-STAT cascade via inhibition of JAK1 activity)|go:"GO:0039645"(modulation by virus of host G1/S transition checkpoint)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039649"(modulation by virus of host ubiquitin-protein ligase activity)|go:"GO:0039686"(bidirectional double-stranded viral DNA replication)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR003133(T antigen, Ori-binding)|interpro:IPR010932(Large T antigen, polyomavirus, C-terminus)|interpro:IPR016392(Large T antigen, polyomaviridae)|interpro:IPR017910|interpro:IPR027417|interpro:IPR036869|rcsb pdb:1EJL|rcsb pdb:1GH6|rcsb pdb:1N25|rcsb pdb:1Q1S|rcsb pdb:1Q1T|rcsb pdb:1SVL|rcsb pdb:1SVM|rcsb pdb:1SVO|rcsb pdb:1TBD|rcsb pdb:1Z1D|rcsb pdb:2FUF|rcsb pdb:2H1L|rcsb pdb:2IF9|rcsb pdb:2IPR|rcsb pdb:2ITJ|rcsb pdb:2ITL|rcsb pdb:2NL8|rcsb pdb:2NTC|interpro:IPR014015(Helicase, superfamily 3, DNA virus)|rcsb pdb:2TBD|rcsb pdb:3QK2|rcsb pdb:3QN2|rcsb pdb:4E2I|rcsb pdb:4FGN|rcsb pdb:4GDF|rcsb pdb:4RXH|rcsb pdb:5D9I|refseq:YP_003708382.1|mint:P03070|dip:DIP-24251N refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N - - - figure legend:Fig. 1B|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2019/10/18 rogid:IMcAp2PRxZXkbJ1eiXhJU9rD2JM1891767 rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606 intact-crc:8716B6C0A591606E|rigid:VZOTDTO282G04bb2R4V1QRGy4IU false - binding-associated region:72-390 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P04637 uniprotkb:P04637 intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5 intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5 psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym) psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368406 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N - - - figure legend:Fig. 1C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606 rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606 intact-crc:101511FA25F771EA|rigid:kC/rRAoXaTQ6ZyHhb+8kNLI3lSs false - binding-associated region:72-390 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P52553 uniprotkb:P43573 intact:EBI-13260|uniprotkb:D6VYK2|ensemblfungi:YLR200W intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W psi-mi:pfd6_yeast(display_long)|uniprotkb:YKE2(gene name)|psi-mi:YKE2(display_short)|uniprotkb:PFD6(gene name synonym)|uniprotkb:YLR200W(locus name)|uniprotkb:L8167.8(orf name)|uniprotkb:GIM1(gene name synonym)|uniprotkb:Genes involved in microtubule biogenesis protein 1(gene name synonym)|uniprotkb:Gim complex subunit 1(gene name synonym) psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368413 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013301.1|sgd:S000004190|mint:P52553|dip:DIP-1333N|ensemblfungi:YLR200W(gene)|ensemblfungi:YLR200W_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin) refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 - - crc64:7E2EE2CEB4708BC3 figure legend:Fig. 1E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:XXTSrL5Q5CrSqYzKV3j3h5/7d10559292 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 intact-crc:6C6CD04ADA6F114A|rigid:tzyZMizCodjf5J6TMev4P2t9/DE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43573 uniprotkb:P20434 intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W intact:EBI-15781|uniprotkb:Q02121|ensemblfungi:YBR154C|uniprotkb:D6VQE9 psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:rpab1_yeast(display_long)|uniprotkb:RPB5(gene name)|psi-mi:RPB5(display_short)|uniprotkb:YBR154C(locus name)|uniprotkb:YBR1204(orf name)|uniprotkb:RPA7(gene name synonym)|uniprotkb:RPC9(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 27 kDa polypeptide(gene name synonym)|uniprotkb:ABC27(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368422 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 rcsb pdb:1I50|rcsb pdb:1I6H|rcsb pdb:1K83|rcsb pdb:1NIK|rcsb pdb:1NT9|rcsb pdb:1PQV|rcsb pdb:1R5U|rcsb pdb:1R9S|rcsb pdb:1R9T|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|rcsb pdb:1SFO|rcsb pdb:1TWA|rcsb pdb:1TWC|rcsb pdb:1TWF|rcsb pdb:1TWG|rcsb pdb:1TWH|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|rcsb pdb:1WCM|rcsb pdb:1Y1V|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|rcsb pdb:1Y1W|rcsb pdb:1Y1Y|rcsb pdb:1Y77|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|rcsb pdb:2B63|rcsb pdb:2B8K|interpro:IPR020608|interpro:IPR020609|rcsb pdb:2E2H|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:1DZF|rcsb pdb:1I3Q|rcsb pdb:2E2I|rcsb pdb:5M64|rcsb pdb:5N5Y|rcsb pdb:5N5Z|rcsb pdb:5N60|rcsb pdb:5N61|rcsb pdb:5OA1|rcsb pdb:5OQJ|rcsb pdb:5OQM|rcsb pdb:5OT2|rcsb pdb:5SVA|rcsb pdb:5U5Q|rcsb pdb:5VVR|rcsb pdb:5VVS|rcsb pdb:5W4U|rcsb pdb:5W51|rcsb pdb:5W5Y|rcsb pdb:5W64|rcsb pdb:5W65|rcsb pdb:5W66|rcsb pdb:6BLO|rcsb pdb:6BLP|rcsb pdb:6BM2|rcsb pdb:6BM4|rcsb pdb:6BQF|rcsb pdb:6CNB|rcsb pdb:6CNC|rcsb pdb:6CND|rcsb pdb:6CNF|rcsb pdb:6EU0|rcsb pdb:6EU1|rcsb pdb:6EU2|rcsb pdb:6EU3|rcsb pdb:6F40|rcsb pdb:6F41|rcsb pdb:5M5Y|rcsb pdb:6F42|rcsb pdb:6F44|rcsb pdb:6GYK|rcsb pdb:6GYL|rcsb pdb:6GYM|rcsb pdb:6H67|rcsb pdb:3I4M|rcsb pdb:3I4N|rcsb pdb:3J0K|rcsb pdb:3J1N|rcsb pdb:3K1F|rcsb pdb:3K7A|rcsb pdb:3M3Y|rcsb pdb:3M4O|rcsb pdb:3PO2|rcsb pdb:3PO3|rcsb pdb:3QT1|rcsb pdb:3RZD|rcsb pdb:3RZO|rcsb pdb:3S14|rcsb pdb:3S15|rcsb pdb:3S16|rcsb pdb:3S17|rcsb pdb:2E2J|rcsb pdb:3S1M|rcsb pdb:3S1N|rcsb pdb:3S1Q|rcsb pdb:3S1R|rcsb pdb:3S2D|ensemblfungi:YBR154C(gene)|ensemblfungi:YBR154C_mRNA(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001172"(transcription, RNA-templated)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042254"(ribosome biogenesis)|rcsb pdb:4A3F|rcsb pdb:4A3G|rcsb pdb:4A3I|rcsb pdb:4A3J|rcsb pdb:4A3K|rcsb pdb:4A3L|rcsb pdb:4A3M|rcsb pdb:4A93|rcsb pdb:4BBR|rcsb pdb:4BBS|rcsb pdb:4BXX|rcsb pdb:4BXZ|rcsb pdb:4BY1|rcsb pdb:4BY7|rcsb pdb:4C2M|rcsb pdb:4C3H|rcsb pdb:3S2H|rcsb pdb:4A3B|rcsb pdb:4A3C|rcsb pdb:4A3D|rcsb pdb:4A3E|rcsb pdb:4C3I|rcsb pdb:4C3J|rcsb pdb:4V1M|rcsb pdb:2JA5|rcsb pdb:2NVZ|rcsb pdb:2R7Z|rcsb pdb:2R92|rcsb pdb:2JA6|rcsb pdb:2R93|rcsb pdb:2VUM|rcsb pdb:2YU9|rcsb pdb:3CQZ|rcsb pdb:3FKI|rcsb pdb:2JA7|rcsb pdb:3GTG|rcsb pdb:2JA8|rcsb pdb:3GTJ|rcsb pdb:3GTK|rcsb pdb:3GTL|rcsb pdb:3GTM|rcsb pdb:3GTO|rcsb pdb:2NVQ|rcsb pdb:3GTP|rcsb pdb:3GTQ|rcsb pdb:3H3V|rcsb pdb:3HOU|rcsb pdb:2NVT|rcsb pdb:2NVX|rcsb pdb:2NVY|rcsb pdb:3HOV|rcsb pdb:3HOW|rcsb pdb:3HOX|rcsb pdb:3HOY|rcsb pdb:3HOZ|rcsb pdb:4X67|rcsb pdb:4X6A|rcsb pdb:4Y52|rcsb pdb:4Y7N|rcsb pdb:4YM7|rcsb pdb:5C3E|rcsb pdb:4V1N|rcsb pdb:4V1O|rcsb pdb:5C44|rcsb pdb:5C4A|rcsb pdb:5C4J|rcsb pdb:5C4X|rcsb pdb:5FJ8|rcsb pdb:5FJ9|rcsb pdb:5FJA|rcsb pdb:5FMF|rcsb pdb:5FYW|rcsb pdb:5FZ5|rcsb pdb:5G5L|rcsb pdb:5IP7|rcsb pdb:5IP9|rcsb pdb:5LMX|rcsb pdb:5M3F|rcsb pdb:5M3M|rcsb pdb:5M5W|rcsb pdb:5M5X|rcsb pdb:6HKO|rcsb pdb:6HLQ|rcsb pdb:6HLR|rcsb pdb:6HLS|rcsb pdb:6I84|rcsb pdb:6O6C|rcsb pdb:6RQH|rcsb pdb:6RQL|rcsb pdb:6RQT|rcsb pdb:6RRD|rcsb pdb:6H68|rcsb pdb:6RUI|rcsb pdb:6RUO|rcsb pdb:6RWE|rcsb pdb:6TPS|rcsb pdb:6TUT|rcsb pdb:6UPX|rcsb pdb:6UPY|rcsb pdb:6UPZ|rcsb pdb:6UQ0|rcsb pdb:6UQ1|rcsb pdb:6UQ3|rcsb pdb:7KED|rcsb pdb:7KEE|rcsb pdb:7KEF|rcsb pdb:7O4I|rcsb pdb:7O4J|rcsb pdb:7O72|rcsb pdb:7O73|rcsb pdb:7O75|reactome:R-SCE-113418|reactome:R-SCE-674695|rcsb pdb:6UQ2|reactome:R-SCE-6781823|reactome:R-SCE-6782135|reactome:R-SCE-6782210|reactome:R-SCE-6796648|reactome:R-SCE-6807505|reactome:R-SCE-72086|reactome:R-SCE-73762|reactome:R-SCE-73772|reactome:R-SCE-73776|reactome:R-SCE-73779|reactome:R-SCE-75953|reactome:R-SCE-75955|reactome:R-SCE-76042|reactome:R-SCE-76061|reactome:R-SCE-76066|reactome:R-SCE-77075|reactome:R-SCE-9018519|refseq:NP_009712.1|sgd:S000000358|dip:DIP-71N|mint:P20434 - crc64:7E2EE2CEB4708BC3 crc64:2A15F7114D69D829 figure legend:Fig. 1E|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 rogid:j/jAJ2fXWf4ebK1aWTWrKERGUpM559292 intact-crc:644B88DEDA47F7A1|rigid:tnQ9o2xDBu/KUtAB/R6yvh40lOI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P25963 uniprotkb:Q04206 intact:EBI-307386|ensembl:ENSP00000216797|uniprotkb:B2R8L6 intact:EBI-73886|ensembl:ENSP00000384273|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1 psi-mi:ikba_human(display_long)|uniprotkb:NFKBIA(gene name)|psi-mi:NFKBIA(display_short)|uniprotkb:IKBA(gene name synonym)|uniprotkb:MAD3(gene name synonym)|uniprotkb:NFKBI(gene name synonym)|uniprotkb:I-kappa-B-alpha(gene name synonym)|uniprotkb:Major histocompatibility complex enhancer-binding protein MAD3(gene name synonym) psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368428 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100906(gene)|ensembl:ENST00000216797(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006915"(apoptotic process)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|refseq:NP_065390.1|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033256"(I-kappaB/NF-kappaB complex)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070427"(nucleotide-binding oligomerization domain containing 1 signaling pathway)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P25963|rcsb pdb:1IKN|rcsb pdb:1NFI|rcsb pdb:6TTU|rcsb pdb:6Y1J|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607764|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-5689880|reactome:R-HSA-9020702|reactome:R-HSA-933542|dip:DIP-139N ensembl:ENSG00000173039(gene)|ensembl:ENST00000406246(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_001138610.1|refseq:NP_068810.3|refseq:NP_001230913.1|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0070301"(cellular response to hydrogen peroxide)|dip:DIP-24238N|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0051607"(defense response to virus)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826 - - - figure legend:Fig. 1D|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:LXYgOHjWhEj5sPeyBEi9kV4ZBP89606 rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606 intact-crc:D8A562FB3A632FA4|rigid:G8PGHZoykwooQXMJhnO7uPyTtq0 false - necessary binding region:303-551 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P43573 uniprotkb:P05753 intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W intact:EBI-16145|uniprotkb:D3DLF2 psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:rs4_yeast(display_long)|uniprotkb:RPS4A(gene name)|psi-mi:RPS4A(display_short)|uniprotkb:RPS7B(gene name synonym)|uniprotkb:YJR145C(locus name)|uniprotkb:J2186(orf name)|uniprotkb:RPS4B(gene name)|psi-mi:RPS4B(display_short)|uniprotkb:RPS7A(gene name synonym)|uniprotkb:YHR203C(locus name)|uniprotkb:S7(gene name synonym)|uniprotkb:YS6(gene name synonym)|uniprotkb:RP5(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368441 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 sgd:S000003906(RPS4A)|sgd:S000001246(RPS4B)|go:"GO:0030686"(90S preribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|interpro:IPR005824(KOW)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|go:"GO:0019843"(rRNA binding)|interpro:IPR013845(Ribosomal protein S4e, central)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR018199|rcsb pdb:3IZB|refseq:NP_012073.1|refseq:NP_012679.1 - crc64:7E2EE2CEB4708BC3 - figure legend:Figure 2A, Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 rogid:0/1PAh0d9haBkt8sGtOf/pKOorg559292 intact-crc:671F32943674DF2F|rigid:QeDAApQ3Z/9VKzMHBm6nCB4hJiQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P36008 uniprotkb:P43573 intact:EBI-6329|uniprotkb:D6VXK6|ensemblfungi:YKL081W intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W psi-mi:ef1g2_yeast(display_long)|uniprotkb:TEF4(gene name)|psi-mi:TEF4(display_short)|uniprotkb:EFC1(gene name synonym)|uniprotkb:Translation elongation factor 1B gamma 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1Bgamma 2(gene name synonym)|uniprotkb:YKL081W(locus name) psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368445 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012842.1|sgd:S000001564|mint:P36008|dip:DIP-6386N|ensemblfungi:YKL081W(gene)|ensemblfungi:YKL081W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433 refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 - crc64:42F1B5B25EF66189 crc64:7E2EE2CEB4708BC3 figure legend:Figure 2A, Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:xGWGR4C1CCep5RzmclTw2JWUroM559292 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 intact-crc:E5A1EC1C4B4BA241|rigid:4SpUfGHpJaQ895e3aCEUj7/eeAA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43573 uniprotkb:P23301 intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W intact:EBI-9033|ensemblfungi:YEL034W|uniprotkb:D3DLL5 psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:if5a1_yeast(display_long)|uniprotkb:Hypusine-containing protein HP2(gene name synonym)|uniprotkb:TIF51A(gene name synonym)|uniprotkb:SYGP-ORF21(orf name)|uniprotkb:YEL034W(locus name)|uniprotkb:HYP2(gene name)|psi-mi:HYP2(display_short)|uniprotkb:eIF-4D(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368449 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|rcsb pdb:3ER0|rcsb pdb:5DAT|rcsb pdb:5DC3|rcsb pdb:5DGE|rcsb pdb:5DGF|rcsb pdb:5GAK|rcsb pdb:5MC6|rcsb pdb:6Q84|rcsb pdb:6TNU|rcsb pdb:7NRC|reactome:R-SCE-204626|ensemblfungi:YEL034W(gene)|ensemblfungi:YEL034W_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006452"(translational frameshifting)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1903272"(positive regulation of cytoplasmic translational elongation through polyproline stretches)|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|refseq:NP_010880.3|sgd:S000000760|mint:P23301|dip:DIP-4230N - crc64:7E2EE2CEB4708BC3 crc64:738F29CCC7820C47 figure legend:Figure 2A, Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 rogid:B9tQQwPUHYgFdA1V67iSN7G/PtY559292 intact-crc:852A6493AC954AC6|rigid:ermj5IlNSiaqmKDxFGDJMKEn180 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43573 uniprotkb:P38912 intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W intact:EBI-8911|ensemblfungi:YMR260C|uniprotkb:D6W086 psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:if1a_yeast(display_long)|uniprotkb:Eukaryotic translation initiation factor 4C(gene name synonym)|uniprotkb:TIF11(gene name)|psi-mi:TIF11(display_short)|uniprotkb:YMR260C(locus name)|uniprotkb:YM8156.02C(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368453 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 ensemblfungi:YMR260C(gene)|ensemblfungi:YMR260C_mRNA(transcript)|go:"GO:0001677"(formation of translation initiation ternary complex)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR001253("Eukaryotic initiation factor 1A (eIF-1A)")|interpro:IPR006196(S1, IF1 type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018104|rcsb pdb:3J80|rcsb pdb:3J81|rcsb pdb:3JAM|rcsb pdb:3JAP|rcsb pdb:3JAQ|rcsb pdb:3WBK|rcsb pdb:6FYX|rcsb pdb:6FYY|rcsb pdb:6GSM|rcsb pdb:6GSN|rcsb pdb:6ZCE|rcsb pdb:6ZU9|reactome:R-SCE-72649|refseq:NP_013987.1|sgd:S000004873|reactome:R-SCE-156827|reactome:R-SCE-72689|reactome:R-SCE-72695|reactome:R-SCE-72702|dip:DIP-4401N - crc64:7E2EE2CEB4708BC3 - figure legend:Figure 2A, Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 rogid:OF3lyXw8ybownFhcLtXCSW19wYU559292 intact-crc:FF6829A8F88EB7BD|rigid:AQZ1RfUukD9RACwBkidS56MwWMU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P11484 uniprotkb:P43573 intact:EBI-8627|uniprotkb:Q05834|uniprotkb:D6VRC7|intact:EBI-29890|ensemblfungi:YDL229W intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W psi-mi:ssb1_yeast(display_long)|uniprotkb:YDL229W(locus name)|uniprotkb:SSB1(gene name)|psi-mi:SSB1(display_short)|uniprotkb:YG101(gene name synonym)|uniprotkb:Cold-inducible protein YG101(gene name synonym)|uniprotkb:Heat shock protein SSB1(gene name synonym)|uniprotkb:Hsp70 chaperone Ssb(gene name synonym) psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368458 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010052.1|sgd:S000002388|mint:P11484|dip:DIP-2254N|ensemblfungi:YDL229W(gene)|ensemblfungi:YDL229W_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006364"(rRNA processing)|go:"GO:0006415"(translational termination)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0006452"(translational frameshifting)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:3GL1 refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 - crc64:F16FA7C25A40321A crc64:7E2EE2CEB4708BC3 figure legend:Figure 2A, Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:JcQIYqdT2cRb6LK9aEQubo2pkkE559292 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 intact-crc:871BB1440A419638|rigid:dz74uimAhBZ/0DcVAu6EioB7Ovw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43573 uniprotkb:P25294 intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W intact:EBI-17244|uniprotkb:D6W1H0|ensemblfungi:YNL007C psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:sis1_yeast(display_long)|uniprotkb:YNL007C(locus name)|uniprotkb:SIS1(gene name)|psi-mi:SIS1(display_short)|uniprotkb:N2879(orf name) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368463 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 refseq:NP_014391.1|sgd:S000004952|ensemblfungi:YNL007C(gene)|ensemblfungi:YNL007C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006413"(translational initiation)|go:"GO:0006457"(protein folding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0035719"(tRNA import into nucleus)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070843"(misfolded protein transport)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072671"(mitochondria-associated ubiquitin-dependent protein catabolic process)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR018253|interpro:IPR036869|rcsb pdb:1C3G|rcsb pdb:2B26|rcsb pdb:4RWU|rcsb pdb:6D6X|go:"GO:0007049"(cell cycle)|dip:DIP-4385N|mint:P25294 - crc64:7E2EE2CEB4708BC3 crc64:642D3709C0FD5682 figure legend:Figure 2A, Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 rogid:gp39i5OLzpajm1XnD9cYtGKD6kU559292 intact-crc:D017F4A225400985|rigid:p7PVN/YTpJfZZ+Nc9ExfdpnwSv4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43573 uniprotkb:P14832 intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W intact:EBI-5463|uniprotkb:D6VSD6|ensemblfungi:YDR155C psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:cyph_yeast(display_long)|uniprotkb:CPR1(gene name)|psi-mi:CPR1(display_short)|uniprotkb:CPH1(gene name synonym)|uniprotkb:SCC1(gene name synonym)|uniprotkb:YDR155C(locus name)|uniprotkb:YD8358.10C(orf name)|uniprotkb:CYP1(gene name synonym)|uniprotkb:Cyclophilin(gene name synonym)|uniprotkb:Cyclosporin A-binding protein(gene name synonym)|uniprotkb:PPI-II(gene name synonym)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368467 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 refseq:NP_010439.1|sgd:S000002562|dip:DIP-5203N|mint:P14832|ensemblfungi:YDR155C(gene)|ensemblfungi:YDR155C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006457"(protein folding)|go:"GO:0015031"(protein transport)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016575"(histone deacetylation)|go:"GO:0030437"(ascospore formation)|go:"GO:0034967"(Set3 complex)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000|rcsb pdb:1IST|rcsb pdb:1VDN - crc64:7E2EE2CEB4708BC3 crc64:012D8E8E4D85B4B7 figure legend:Figure 2A, Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 rogid:ytAesNyLcntrLis8Ts7FuX0lNkw559292 intact-crc:870DD6A106A28B35|rigid:RelMVPdQlhN+RTnLr2IYmpDnRYo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P20081 uniprotkb:P43573 intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym) psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368471 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 - crc64:65C134830D300C06 crc64:7E2EE2CEB4708BC3 figure legend:Figure 2A, Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 intact-crc:C7300E79C88C3D77|rigid:c9Gq/VCFuNXmo2pmBWrEovU3EmM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P38879 uniprotkb:P43573 intact:EBI-6379|uniprotkb:D3DLE1|ensemblfungi:YHR193C intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W psi-mi:naca_yeast(display_long)|uniprotkb:EGD2(gene name)|psi-mi:EGD2(display_short)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:GAL4 DNA-binding enhancer protein 2(gene name synonym)|uniprotkb:YHR193C(locus name) psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368660 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000001236|refseq:NP_012063.3|mint:P38879|dip:DIP-2098N|ensemblfungi:YHR193C(gene)|ensemblfungi:YHR193C_mRNA(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR009060(UBA-like)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034 refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 - crc64:86CE0C4E6194C286 crc64:7E2EE2CEB4708BC3 figure legend:Figure 2A, Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:IjsgR+hZDgTQDvy2Wf8JEX4kF+A559292 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 intact-crc:9A19E5236BE95A14|rigid:YPw0Rna5msriHH9oWWyNp1+5tjA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P00560 uniprotkb:P43573 intact:EBI-13275|uniprotkb:D6VR21|ensemblfungi:YCR012W intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W psi-mi:pgk_yeast(display_long)|uniprotkb:PGK1(gene name)|psi-mi:PGK1(display_short)|uniprotkb:YCR12W(orf name)|uniprotkb:YCR012W(locus name) psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368665 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009938.2|sgd:S000000605|mint:P00560|dip:DIP-4152N|ensemblfungi:YCR012W(gene)|ensemblfungi:YCR012W_mRNA(transcript)|go:"GO:0004618"(phosphoglycerate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0043531"(ADP binding)|interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR036043|rcsb pdb:1FW8|rcsb pdb:1QPG|rcsb pdb:3PGK|reactome:R-SCE-70171|reactome:R-SCE-70263 refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 - crc64:378AB944DB34EFF0 crc64:7E2EE2CEB4708BC3 figure legend:Figure 2A, Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:YvdII56D8+8lpnsTePzSqOlMcBI559292 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 intact-crc:858E15E9F9C91C45|rigid:8t1hdL3CbUFKjDAhvMzhSreWfOg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43573 uniprotkb:P35732 intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W intact:EBI-26695|uniprotkb:D6VXN3|ensemblfungi:YKL054C psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:def1_yeast(display_long)|uniprotkb:YKL054C(locus name)|uniprotkb:YKL308(orf name)|uniprotkb:DEF1(gene name)|psi-mi:DEF1(display_short)|uniprotkb:RIP1(gene name synonym)|uniprotkb:VID31(gene name synonym)|uniprotkb:RRM3-interacting protein 1(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368690 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 refseq:NP_012869.1|sgd:S000001537|mint:P35732|dip:DIP-6354N|ensemblfungi:YKL054C(gene)|ensemblfungi:YKL054C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR003892(Ubiquitin system component Cue)|interpro:IPR041803 - crc64:7E2EE2CEB4708BC3 crc64:05734E2D0B7389AC figure legend:Figure 2A, Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 rogid:2MGY7dFkcxjXHgm+k9iBW8E7tuk559292 intact-crc:705172D79B0145C6|rigid:xOCJOTeMRXz+H4BmWuYep0Z/G9s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P22203 uniprotkb:P43573 intact:EBI-20268|uniprotkb:D6W328|ensemblfungi:YOR332W intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W psi-mi:vate_yeast(display_long)|uniprotkb:VMA4(gene name)|psi-mi:VMA4(display_short)|uniprotkb:VAT5(gene name synonym)|uniprotkb:O6241(orf name)|uniprotkb:YOR332W(locus name)|uniprotkb:Vacuolar proton pump subunit E(gene name synonym)|uniprotkb:V-ATPase 27 kDa subunit(gene name synonym) psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368701 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) reactome:R-SCE-77387|sgd:S000005859|reactome:R-SCE-1222556|refseq:NP_014977.3|ensemblfungi:YOR332W(gene)|ensemblfungi:YOR332W_mRNA(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|interpro:IPR002842(ATPase, V1/A1 complex, subunit E)|interpro:IPR038495|rcsb pdb:2KZ9|rcsb pdb:3J9T|rcsb pdb:3J9U|rcsb pdb:3J9V|rcsb pdb:4DL0|rcsb pdb:4EFA|rcsb pdb:5BW9|rcsb pdb:5D80|rcsb pdb:5VOX|rcsb pdb:5VOY|rcsb pdb:5VOZ|rcsb pdb:6O7V|rcsb pdb:6O7W|rcsb pdb:6O7X|dip:DIP-4595N|reactome:R-SCE-917977|reactome:R-SCE-9639288 refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 - crc64:7AC5169FF7E5A39C crc64:7E2EE2CEB4708BC3 figure legend:Figure 2A, Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:g5fE3fwOSqcB4fXde9P8p6BD4T8559292 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 intact-crc:34900A8B29ADB1FF|rigid:pzJe7t7YNFA44Z+64WBaoBn82ug false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43573 uniprotkb:P32319 intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W intact:EBI-13123|uniprotkb:D6VPY3|ensemblfungi:YBL017C psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:vps10_yeast(display_long)|uniprotkb:PEP1(gene name)|psi-mi:PEP1(display_short)|uniprotkb:Vacuolar carboxypeptidase sorting receptor VPS10(gene name synonym)|uniprotkb:Carboxypeptidase Y receptor(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 10(gene name synonym)|uniprotkb:Vacuolar protein-targeting protein 1(gene name synonym)|uniprotkb:Carboxypeptidase Y-deficient protein 1(gene name synonym)|uniprotkb:Sortilin VPS10(gene name synonym)|uniprotkb:VPS10(gene name synonym)|uniprotkb:VPT1(gene name synonym)|uniprotkb:YBL03.22(orf name)|uniprotkb:YBL0302(orf name)|uniprotkb:YBL017C(locus name) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368721 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 refseq:NP_009536.1|sgd:S000000113|mint:P32319|dip:DIP-5900N|ensemblfungi:YBL017C(gene)|ensemblfungi:YBL017C_mRNA(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0000423"(mitophagy)|go:"GO:0000425"(pexophagy)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006896"(Golgi to vacuole transport)|go:"GO:0007034"(vacuolar transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048203"(vesicle targeting, trans-Golgi to endosome)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR036278 - crc64:7E2EE2CEB4708BC3 crc64:C778A0400612ECF4 figure legend:Figure 2A, Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 rogid:dYYsekAaDw4SzmEUSe5tYb5a43M559292 intact-crc:1D3F5B983CC44CF2|rigid:H7fLwgsHlWts2swnAoB7ekt8TTM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P32476 uniprotkb:P43573 intact:EBI-6545|uniprotkb:D6VUW0|ensemblfungi:YGR175C intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W psi-mi:erg1_yeast(display_long)|uniprotkb:YGR175C(locus name)|uniprotkb:ERG1(gene name)|psi-mi:ERG1(display_short)|uniprotkb:Squalene epoxidase(gene name synonym) psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368730 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_011691.1|sgd:S000003407|reactome:R-SCE-191273|dip:DIP-6325N|ensemblfungi:YGR175C(gene)|ensemblfungi:YGR175C_mRNA(transcript)|go:"GO:0004506"(squalene monooxygenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0006696"(ergosterol biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR013698(Squalene epoxidase)|interpro:IPR036188|interpro:IPR040125 refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 - crc64:BBEFD766634855E8 crc64:7E2EE2CEB4708BC3 figure legend:Figure 2A, Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:vKJFukN2Wlwj1Rcv9t4zgCcCrJ4559292 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 intact-crc:B44F8B6A99497F8F|rigid:G5+iWcQhRUPZe3JD8Aoh15yuGE0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43573 uniprotkb:P02994 intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W intact:EBI-6314|uniprotkb:Q7Z7U8|uniprotkb:Q7Z8Q8|uniprotkb:Q7Z8Q9|uniprotkb:D6VQB6|ensemblfungi:YBR118W|ensemblfungi:YPR080W psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:ef1a_yeast(display_long)|uniprotkb:TEF1(gene name)|psi-mi:TEF1(display_short)|uniprotkb:YPR080W(locus name)|uniprotkb:P9513.7(orf name)|uniprotkb:TEF2(gene name)|psi-mi:TEF2(display_short)|uniprotkb:YBR118W(locus name)|uniprotkb:YBR0913(orf name)|uniprotkb:Translation elongation factor 1A(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1A(gene name synonym) psi-mi:"MI:0112"(ubiquitin reconstruction) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368758 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 refseq:NP_009676.1|refseq:NP_015405.1|sgd:S000006284|sgd:S000000322|mint:P02994|dip:DIP-2250N|ensemblfungi:YBR118W(gene)|ensemblfungi:YBR118W_mRNA(transcript)|ensemblfungi:YPR080W(gene)|ensemblfungi:YPR080W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043022"(ribosome binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:1904408"(melatonin binding)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|rcsb pdb:1F60|rcsb pdb:1G7C|rcsb pdb:1IJE|rcsb pdb:1IJF|rcsb pdb:2B7B|rcsb pdb:2B7C|rcsb pdb:5O8W|reactome:R-SCE-156842|reactome:R-SCE-3371511|reactome:R-SCE-6798695|reactome:R-SCE-8876725 - crc64:7E2EE2CEB4708BC3 crc64:411C66D830716576 figure legend:Figure 2A, Table 1|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 rogid:u3vFHdbpfo8w7GJh4nHkx/KQRAk559292 intact-crc:DC7BC7F779BA95C4|rigid:XTcT1qKStRIbELqueuBxgVRn4V4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P43573 uniprotkb:P11484 intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W intact:EBI-8627|uniprotkb:Q05834|uniprotkb:D6VRC7|intact:EBI-29890|ensemblfungi:YDL229W psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:ssb1_yeast(display_long)|uniprotkb:YDL229W(locus name)|uniprotkb:SSB1(gene name)|psi-mi:SSB1(display_short)|uniprotkb:YG101(gene name synonym)|uniprotkb:Cold-inducible protein YG101(gene name synonym)|uniprotkb:Heat shock protein SSB1(gene name synonym)|uniprotkb:Hsp70 chaperone Ssb(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368769 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 refseq:NP_010052.1|sgd:S000002388|mint:P11484|dip:DIP-2254N|ensemblfungi:YDL229W(gene)|ensemblfungi:YDL229W_mRNA(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006364"(rRNA processing)|go:"GO:0006415"(translational termination)|go:"GO:0006450"(regulation of translational fidelity)|go:"GO:0006452"(translational frameshifting)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051083"('de novo' cotranslational protein folding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:3GL1 - crc64:7E2EE2CEB4708BC3 crc64:F16FA7C25A40321A figure legend:Figure 2C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 rogid:JcQIYqdT2cRb6LK9aEQubo2pkkE559292 intact-crc:28F3B4D1C1DC5710|rigid:dz74uimAhBZ/0DcVAu6EioB7Ovw false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P43573 uniprotkb:P20081 intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368780 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT - crc64:7E2EE2CEB4708BC3 crc64:65C134830D300C06 figure legend:Figure 2C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292 intact-crc:DB4DCEC661C67098|rigid:c9Gq/VCFuNXmo2pmBWrEovU3EmM false myc tag:?-? ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P02994 uniprotkb:P43573 intact:EBI-6314|uniprotkb:Q7Z7U8|uniprotkb:Q7Z8Q8|uniprotkb:Q7Z8Q9|uniprotkb:D6VQB6|ensemblfungi:YBR118W|ensemblfungi:YPR080W intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W psi-mi:ef1a_yeast(display_long)|uniprotkb:TEF1(gene name)|psi-mi:TEF1(display_short)|uniprotkb:YPR080W(locus name)|uniprotkb:P9513.7(orf name)|uniprotkb:TEF2(gene name)|psi-mi:TEF2(display_short)|uniprotkb:YBR118W(locus name)|uniprotkb:YBR0913(orf name)|uniprotkb:Translation elongation factor 1A(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1A(gene name synonym) psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368789 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009676.1|refseq:NP_015405.1|sgd:S000006284|sgd:S000000322|mint:P02994|dip:DIP-2250N|ensemblfungi:YBR118W(gene)|ensemblfungi:YBR118W_mRNA(transcript)|ensemblfungi:YPR080W(gene)|ensemblfungi:YPR080W_mRNA(transcript)|go:"GO:0000329"(fungal-type vacuole membrane)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043022"(ribosome binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:1904408"(melatonin binding)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|rcsb pdb:1F60|rcsb pdb:1G7C|rcsb pdb:1IJE|rcsb pdb:1IJF|rcsb pdb:2B7B|rcsb pdb:2B7C|rcsb pdb:5O8W|reactome:R-SCE-156842|reactome:R-SCE-3371511|reactome:R-SCE-6798695|reactome:R-SCE-8876725 refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 - crc64:411C66D830716576 crc64:7E2EE2CEB4708BC3 figure legend:Figure 2C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:u3vFHdbpfo8w7GJh4nHkx/KQRAk559292 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 intact-crc:08EC4A7E2B22B16A|rigid:XTcT1qKStRIbELqueuBxgVRn4V4 false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P36008 uniprotkb:P43573 intact:EBI-6329|uniprotkb:D6VXK6|ensemblfungi:YKL081W intact:EBI-22787|uniprotkb:D6VTK7|ensemblfungi:YFL023W psi-mi:ef1g2_yeast(display_long)|uniprotkb:TEF4(gene name)|psi-mi:TEF4(display_short)|uniprotkb:EFC1(gene name synonym)|uniprotkb:Translation elongation factor 1B gamma 2(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1Bgamma 2(gene name synonym)|uniprotkb:YKL081W(locus name) psi-mi:bud27_yeast(display_long)|uniprotkb:YFL023W(locus name)|uniprotkb:BUD27(gene name)|psi-mi:BUD27(display_short)|uniprotkb:URI(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mockli et al. (2007) pubmed:17612295 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1368798 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_012842.1|sgd:S000001564|mint:P36008|dip:DIP-6386N|ensemblfungi:YKL081W(gene)|ensemblfungi:YKL081W_mRNA(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010494"(cytoplasmic stress granule)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433 refseq:NP_683715.1|sgd:S000001871|dip:DIP-4929N|mint:P43573|ensemblfungi:YFL023W(gene)|ensemblfungi:YFL023W_mRNA(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0005737"(cytoplasm)|go:"GO:1990113"(RNA polymerase I assembly)|go:"GO:1990114"(RNA polymerase II core complex assembly)|go:"GO:1990115"(RNA polymerase III assembly)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR024325 - crc64:42F1B5B25EF66189 crc64:7E2EE2CEB4708BC3 figure legend:Figure 2C|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/07/11 2014/10/16 rogid:xGWGR4C1CCep5RzmclTw2JWUroM559292 rogid:suEOJpZPQ5o+NkxiPl9X0Yqt+Nc559292 intact-crc:B870124BAB07257E|rigid:4SpUfGHpJaQ895e3aCEUj7/eeAA false ha tag:?-? myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)