#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9UQ07 uniprotkb:P25815 intact:EBI-1388900|uniprotkb:B2R6Z4|uniprotkb:B7Z7P6|uniprotkb:E7ER76|uniprotkb:E7ERR8|uniprotkb:Q92790|uniprotkb:Q93067|ensembl:ENSP00000355304 intact:EBI-743700|uniprotkb:Q5J7W2|ensembl:ENSP00000296370 psi-mi:mok_human(display_long)|uniprotkb:RAGE1(gene name synonym)|uniprotkb:MOK protein kinase(gene name synonym)|uniprotkb:Renal tumor antigen 1(gene name synonym)|uniprotkb:MOK(gene name)|psi-mi:MOK(display_short)|uniprotkb:RAGE(gene name synonym) psi-mi:s100p_human(display_long)|uniprotkb:S100 calcium-binding protein P(gene name synonym)|uniprotkb:S100P(gene name)|psi-mi:S100P(display_short)|uniprotkb:S100E(gene name synonym)|uniprotkb:Protein S100-E(gene name synonym)|uniprotkb:Migration-inducing gene 9 protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Fuentes et al. (2007) pubmed:17587138 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1388938 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055041.1|refseq:NP_001317163.1|refseq:NP_001258940.1|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000080823(gene)|ensembl:ENST00000361847(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site) refseq:NP_005971.1|ensembl:ENSG00000163993(gene)|ensembl:ENST00000296370(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010033"(response to organic substance)|go:"GO:0031528"(microvillus membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR034325|rcsb pdb:1J55|rcsb pdb:1OZO|rcsb pdb:2MJW|reactome:R-HSA-6798695|interpro:IPR011992(EF-Hand type) omim:114500(primary-reference) - - figure legend:4 A|inhibition:AmphP - Coincubating the samples with AmphP inhibited the interaction of S100P and RAGE. AmphP is a peptide derived from the RAGE ligand, amphoterin, which functions as a competitive antagonist to RAGE.|dataset:Cancer - Interactions investigated in the context of cancer taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/08/31 2014/10/16 rogid:5aY9xKiNzvz9SCiixMmocAwdnHU9606 rogid:wuvwIPFST5gUGqRSJmkUw+CbJv49606 intact-crc:CC082E8B73B3B763|rigid:/Txk5KWF9sgrUWGDxCDOBueM8mA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)