#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P0CS91	uniprotkb:P42844	intact:EBI-7276682|uniprotkb:P12398|uniprotkb:D6VWL6|intact:MINT-665405	intact:EBI-28366|uniprotkb:D6W0N5|ensemblfungi:YNL310C	psi-mi:hsp77_yeasx(display_long)|uniprotkb:Heat shock protein SSC1, mitochondrial(gene name synonym)|uniprotkb:SSC1(gene name)|psi-mi:SSC1(display_short)|uniprotkb:ENS1(gene name synonym)|uniprotkb:mtHSP70(gene name synonym)|uniprotkb:Endonuclease SceI 75 kDa subunit(gene name synonym)	psi-mi:zim17_yeast(display_long)|uniprotkb:TIM15(gene name synonym)|uniprotkb:N0381(orf name)|uniprotkb:YNL310C(locus name)|uniprotkb:FMP28(gene name synonym)|uniprotkb:HEP1(gene name synonym)|uniprotkb:mtHsp70-associated motor and chaperone protein TIM15/ZIM17(gene name synonym)|uniprotkb:ZIM17(gene name)|psi-mi:ZIM17(display_short)|uniprotkb:Mitochondrial import inner membrane translocase subunit TIM15(gene name synonym)|uniprotkb:mtHsp70 escort protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Momose et al. (2007)	pubmed:17571076|imex:IM-11178|mint:MINT-5220029	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7462724|mint:MINT-4979135|imex:IM-11178-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P0CS91|interpro:IPR018181|go:"GO:0005524"(ATP binding)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR029047|interpro:IPR029048|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR043129|mint:MINT-4979136(identity)	refseq:NP_014089.2|sgd:S000005254|interpro:IPR024158|interpro:IPR007853(Zinc finger, Zim17-type)|mint:P42844|ensemblfungi:YNL310C(gene)|ensemblfungi:YNL310C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|rcsb pdb:2E2Z|mint:MINT-4979140(identity)	-	comment:mint|function:Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Constitutes the ATP-driven core of the motor and binds the precursor preprotein. Required for the import of the processed fratxin homolog YFH1 into the mitochondrion|function:"Acts as a non-catalytic component of endonuclease SceI (endo.SceI), which cleaves specifically at multiple sites on mitochondrial DNA and produces double-stranded breaks. SSC1 confers broader sequence specificity, greater stability, and higher activity on the catalytic subunit"	-	figure legend:F4A|figure legend:F3F|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/07	2014/10/16	rogid:FXa2UGax9Df8Mcz1y8joh1oE1kU4932	rogid:AK0Awmgt3V8zBG559D/FsFlnoVI559292	intact-crc:18DE9C8A8E351A67|rigid:vf465vQM8MVeM2vQLTeHslSzR04	false	-	mutation disrupting interaction:111-111(MINT-4979145)|glutathione s tranferase tag:?-?(MINT-4979141)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P0CS91	uniprotkb:P42844	intact:EBI-7276682|uniprotkb:P12398|uniprotkb:D6VWL6|intact:MINT-665405	intact:EBI-28366|uniprotkb:D6W0N5|ensemblfungi:YNL310C	psi-mi:hsp77_yeasx(display_long)|uniprotkb:Heat shock protein SSC1, mitochondrial(gene name synonym)|uniprotkb:SSC1(gene name)|psi-mi:SSC1(display_short)|uniprotkb:ENS1(gene name synonym)|uniprotkb:mtHSP70(gene name synonym)|uniprotkb:Endonuclease SceI 75 kDa subunit(gene name synonym)	psi-mi:zim17_yeast(display_long)|uniprotkb:TIM15(gene name synonym)|uniprotkb:N0381(orf name)|uniprotkb:YNL310C(locus name)|uniprotkb:FMP28(gene name synonym)|uniprotkb:HEP1(gene name synonym)|uniprotkb:mtHsp70-associated motor and chaperone protein TIM15/ZIM17(gene name synonym)|uniprotkb:ZIM17(gene name)|psi-mi:ZIM17(display_short)|uniprotkb:Mitochondrial import inner membrane translocase subunit TIM15(gene name synonym)|uniprotkb:mtHsp70 escort protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Momose et al. (2007)	pubmed:17571076|imex:IM-11178|mint:MINT-5220029	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7462746|mint:MINT-4979152|imex:IM-11178-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P0CS91|interpro:IPR018181|go:"GO:0005524"(ATP binding)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR029047|interpro:IPR029048|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR043129|mint:MINT-4979161(identity)	refseq:NP_014089.2|sgd:S000005254|interpro:IPR024158|interpro:IPR007853(Zinc finger, Zim17-type)|mint:P42844|ensemblfungi:YNL310C(gene)|ensemblfungi:YNL310C_mRNA(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|rcsb pdb:2E2Z|mint:MINT-4979153(identity)	-	comment:mint|function:Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Constitutes the ATP-driven core of the motor and binds the precursor preprotein. Required for the import of the processed fratxin homolog YFH1 into the mitochondrion|function:"Acts as a non-catalytic component of endonuclease SceI (endo.SceI), which cleaves specifically at multiple sites on mitochondrial DNA and produces double-stranded breaks. SSC1 confers broader sequence specificity, greater stability, and higher activity on the catalytic subunit"	-	figure legend:F4A|figure legend:F3F|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/07	2014/10/16	rogid:FXa2UGax9Df8Mcz1y8joh1oE1kU4932	rogid:AK0Awmgt3V8zBG559D/FsFlnoVI559292	intact-crc:7A6CC43407AEEDB7|rigid:vf465vQM8MVeM2vQLTeHslSzR04	false	-	mutation disrupting interaction:106-106(MINT-4979154)|glutathione s tranferase tag:?-?(MINT-4979158)|mutation disrupting interaction:107-107(MINT-4979165)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0396"(predetermined participant)