#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P20081 uniprotkb:Q9FR53 intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C intact:EBI-1382370|uniprotkb:Q9LPM4|ensemblplants:AT1G50030.1 psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym) psi-mi:tor_arath(display_long)|uniprotkb:TOR(gene name)|psi-mi:TOR(display_short)|uniprotkb:At1g50030(locus name)|uniprotkb:Protein TARGET OF RAPAMYCIN(gene name synonym)|uniprotkb:F2J10.19(orf name) psi-mi:"MI:0096"(pull down) Sormani et al. (2007) pubmed:17543119|imex:IM-19962 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1382386|imex:IM-19962-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT refseq:NP_175425.2|dip:DIP-39421N|mint:Q9FR53|ensemblplants:AT1G50030(gene)|ensemblplants:AT1G50030.1(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006952"(defense response)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009615"(response to virus)|go:"GO:0009630"(gravitropism)|go:"GO:0009688"(abscisic acid biosynthetic process)|go:"GO:0009733"(response to auxin)|go:"GO:0009734"(auxin-activated signaling pathway)|go:"GO:0009742"(brassinosteroid mediated signaling pathway)|go:"GO:0009745"(sucrose mediated signaling)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009793"(embryo development ending in seed dormancy)|go:"GO:0010116"(positive regulation of abscisic acid biosynthetic process)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010929"(positive regulation of auxin mediated signaling pathway)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900459"(positive regulation of brassinosteroid mediated signaling pathway)|go:"GO:1901355"(response to rapamycin)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940 - crc64:65C134830D300C06 - figure legend:1C|caution:"FKBP12 (P20081) was identified by sequence similarity search using MPsrch according to the critrea set out in the IntAct annotation manual. The atTOR protein was identified from a reference in the text."|agonist:rapamycin|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") - 2007/08/13 2014/10/16 rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292 rogid:HOVOVeVKMJXATEByDcbzD0QLL9g3702 intact-crc:3B9762524B90B965|rigid:3pdyZybPo/bDk+c2N6qSGeu0L5U false his tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P20081 uniprotkb:Q9FR53 intact:EBI-6961|uniprotkb:D6W147|ensemblfungi:YNL135C intact:EBI-1382370|uniprotkb:Q9LPM4|ensemblplants:AT1G50030.1 psi-mi:fkbp_yeast(display_long)|uniprotkb:RBP1(gene name synonym)|uniprotkb:N1213(orf name)|uniprotkb:N1845(orf name)|uniprotkb:YNL135C(locus name)|uniprotkb:FPR1(gene name)|psi-mi:FPR1(display_short)|uniprotkb:FKB1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase(gene name synonym)|uniprotkb:Rapamycin-binding protein(gene name synonym) psi-mi:tor_arath(display_long)|uniprotkb:TOR(gene name)|psi-mi:TOR(display_short)|uniprotkb:At1g50030(locus name)|uniprotkb:Protein TARGET OF RAPAMYCIN(gene name synonym)|uniprotkb:F2J10.19(orf name) psi-mi:"MI:0018"(two hybrid) Sormani et al. (2007) pubmed:17543119|imex:IM-19962 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1382405|imex:IM-19962-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_014264.1|sgd:S000005079|dip:DIP-1263N|mint:P20081|ensemblfungi:YNL135C(gene)|ensemblfungi:YNL135C_mRNA(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005527"(macrolide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006457"(protein folding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901710"(regulation of homoserine biosynthetic process)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|rcsb pdb:1YAT refseq:NP_175425.2|dip:DIP-39421N|mint:Q9FR53|ensemblplants:AT1G50030(gene)|ensemblplants:AT1G50030.1(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006952"(defense response)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009615"(response to virus)|go:"GO:0009630"(gravitropism)|go:"GO:0009688"(abscisic acid biosynthetic process)|go:"GO:0009733"(response to auxin)|go:"GO:0009734"(auxin-activated signaling pathway)|go:"GO:0009742"(brassinosteroid mediated signaling pathway)|go:"GO:0009745"(sucrose mediated signaling)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009793"(embryo development ending in seed dormancy)|go:"GO:0010116"(positive regulation of abscisic acid biosynthetic process)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010929"(positive regulation of auxin mediated signaling pathway)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0016303"(1-phosphatidylinositol-3-kinase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031931"(TORC1 complex)|go:"GO:0031932"(TORC2 complex)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900459"(positive regulation of brassinosteroid mediated signaling pathway)|go:"GO:1901355"(response to rapamycin)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR009076(FKBP12-rapamycin-associated protein, FKBP12-rapamycin-binding)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR024585|interpro:IPR026683|interpro:IPR036738|interpro:IPR036940 - crc64:65C134830D300C06 - figure legend:1B|caution:"FKBP12 (P20081) was identified by sequence similarity search using MPsrch according to the critrea set out in the IntAct annotation manual. The atTOR protein was identified from a reference in the text."|agonist:rapamycin|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/08/13 2014/10/16 rogid:8afvGSk+mPghtqkVoWd2rHJXXhQ559292 rogid:HOVOVeVKMJXATEByDcbzD0QLL9g3702 intact-crc:F35C34BCD8A13A24|rigid:3pdyZybPo/bDk+c2N6qSGeu0L5U false - sufficient binding region:1851-2050 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)