#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q7T103	uniprotkb:P87377	intact:EBI-7438970|uniprotkb:A9CDQ2|intact:MINT-4979275|uniprotkb:Q99293	intact:EBI-7439000|uniprotkb:B7ZS85|uniprotkb:P87386|intact:MINT-4979289|uniprotkb:B1H1N4|uniprotkb:A2BDB3|uniprotkb:P79930	psi-mi:p5f11_xenla(display_long)|uniprotkb:oct-25(gene name synonym)|uniprotkb:pou5f1.1(gene name)|psi-mi:pou5f1.1(display_short)|uniprotkb:POU class V protein oct-25(gene name synonym)	psi-mi:vegta_xenla(display_long)|uniprotkb:vegt-a(gene name)|psi-mi:vegt-a(display_short)|uniprotkb:Brachyury and Tbx-related protein(gene name synonym)|uniprotkb:T-box protein Antipodean(gene name synonym)|uniprotkb:apod(gene name synonym)|uniprotkb:brat(gene name synonym)|uniprotkb:vegt(gene name synonym)	psi-mi:"MI:0096"(pull down)	Cao et al. (2007)	pubmed:17541407|imex:IM-10834|mint:MINT-5219975	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7439028|mint:MINT-4979309|imex:IM-10834-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q7T103|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|refseq:NP_001079832.1|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR013847(POU)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007369"(gastrulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|mint:MINT-4979310(identity)	mint:P87377|refseq:XP_018088382.1|interpro:IPR018186|refseq:NP_001081665.1|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR001699(Transcription factor, T-box)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR036960|mint:MINT-4979311(identity)	-	comment:mint	comment:mint|function:Transcription factor involved in mesodermal patterning. Appears to pattern mesoderm along the dorsoventral and posterior axis. It activates WNT-8, EOMES and brachyury expression	figure legend:F3A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/07	2014/10/16	rogid:1W55S33qOMdyucj4w1befdCOH+08355	rogid:Fprh3NdbFqyzEK1Fq7c4nYqOII88355	intact-crc:598C58560A80B2EF|rigid:vXHM1BOvhBoRvmNidmnu1uT3WVc	false	glutathione s tranferase tag:?-?(MINT-4979315)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q90ZB6	uniprotkb:Q7T103	intact:EBI-7439087|intact:MINT-4979333|uniprotkb:Q6DD63	intact:EBI-7438970|uniprotkb:A9CDQ2|intact:MINT-4979275|uniprotkb:Q99293	psi-mi:t7l1b_xenla(display_long)|uniprotkb:tcf7l1-b(gene name)|psi-mi:tcf7l1-b(display_short)|uniprotkb:HMG box transcription factor 3-B(gene name synonym)|uniprotkb:tcf3(gene name synonym)|uniprotkb:tcf3b(gene name synonym)	psi-mi:p5f11_xenla(display_long)|uniprotkb:oct-25(gene name synonym)|uniprotkb:pou5f1.1(gene name)|psi-mi:pou5f1.1(display_short)|uniprotkb:POU class V protein oct-25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Cao et al. (2007)	pubmed:17541407|imex:IM-10834|mint:MINT-5219975	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7439081|mint:MINT-4979323|imex:IM-10834-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q90ZB6|interpro:IPR024940|refseq:NP_001080938.1|interpro:IPR027397|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR009071(High mobility group box, HMG)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR036910|interpro:IPR028778|mint:MINT-4979329(identity)	mint:Q7T103|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|refseq:NP_001079832.1|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR013847(POU)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007369"(gastrulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|mint:MINT-4979324(identity)	-	comment:mint|function:Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of ctnnb1-A and possibly ctnnb1-B, and as an activator in the presence of these proteins. Required early in development for the establishment of the dorsal body axis in response to maternal Wnt signaling	comment:mint	figure legend:F3A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/07	2014/10/16	rogid:ach7fn3ORk+raay2+9hHm6BmgyY8355	rogid:1W55S33qOMdyucj4w1befdCOH+08355	intact-crc:6103532638B6FFC8|rigid:6HRaKHesam5KdUWT3u00ePj5Y0A	false	-	glutathione s tranferase tag:?-?(MINT-4979326)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7T103	uniprotkb:P87377	intact:EBI-7438970|uniprotkb:A9CDQ2|intact:MINT-4979275|uniprotkb:Q99293	intact:EBI-7439000|uniprotkb:B7ZS85|uniprotkb:P87386|intact:MINT-4979289|uniprotkb:B1H1N4|uniprotkb:A2BDB3|uniprotkb:P79930	psi-mi:p5f11_xenla(display_long)|uniprotkb:oct-25(gene name synonym)|uniprotkb:pou5f1.1(gene name)|psi-mi:pou5f1.1(display_short)|uniprotkb:POU class V protein oct-25(gene name synonym)	psi-mi:vegta_xenla(display_long)|uniprotkb:vegt-a(gene name)|psi-mi:vegt-a(display_short)|uniprotkb:Brachyury and Tbx-related protein(gene name synonym)|uniprotkb:T-box protein Antipodean(gene name synonym)|uniprotkb:apod(gene name synonym)|uniprotkb:brat(gene name synonym)|uniprotkb:vegt(gene name synonym)	psi-mi:"MI:0096"(pull down)	Cao et al. (2007)	pubmed:17541407|imex:IM-10834|mint:MINT-5219975	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7439118|mint:MINT-4979347|imex:IM-10834-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q7T103|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|refseq:NP_001079832.1|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR013847(POU)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007369"(gastrulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|mint:MINT-4979348(identity)	mint:P87377|refseq:XP_018088382.1|interpro:IPR018186|refseq:NP_001081665.1|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR001699(Transcription factor, T-box)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR036960|mint:MINT-4979353(identity)	-	comment:mint	comment:mint|function:Transcription factor involved in mesodermal patterning. Appears to pattern mesoderm along the dorsoventral and posterior axis. It activates WNT-8, EOMES and brachyury expression	figure legend:F3A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/07	2014/10/16	rogid:1W55S33qOMdyucj4w1befdCOH+08355	rogid:Fprh3NdbFqyzEK1Fq7c4nYqOII88355	intact-crc:8752758E939D906C|rigid:vXHM1BOvhBoRvmNidmnu1uT3WVc	false	-	glutathione s tranferase tag:?-?(MINT-4979358)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q90ZB6	uniprotkb:B7ZQA9	intact:EBI-7439087|intact:MINT-4979333|uniprotkb:Q6DD63	intact:EBI-7439185|intact:MINT-4979404|uniprotkb:Q03917|uniprotkb:Q9PSI7	psi-mi:t7l1b_xenla(display_long)|uniprotkb:tcf7l1-b(gene name)|psi-mi:tcf7l1-b(display_short)|uniprotkb:HMG box transcription factor 3-B(gene name synonym)|uniprotkb:tcf3(gene name synonym)|uniprotkb:tcf3b(gene name synonym)	psi-mi:p5f12_xenla(display_long)|uniprotkb:oct-91(gene name synonym)|uniprotkb:POU class V protein oct-91(gene name synonym)|uniprotkb:pou5f1.2(gene name)|psi-mi:pou5f1.2(display_short)	psi-mi:"MI:0096"(pull down)	Cao et al. (2007)	pubmed:17541407|imex:IM-10834|mint:MINT-5219975	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7439206|mint:MINT-4979394|imex:IM-10834-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q90ZB6|interpro:IPR024940|refseq:NP_001080938.1|interpro:IPR027397|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR009071(High mobility group box, HMG)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR036910|interpro:IPR028778|mint:MINT-4979395(identity)	mint:B7ZQA9|refseq:NP_001081342.1|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR013847(POU)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007369"(gastrulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|mint:MINT-4979398(identity)	-	comment:mint|function:Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of ctnnb1-A and possibly ctnnb1-B, and as an activator in the presence of these proteins. Required early in development for the establishment of the dorsal body axis in response to maternal Wnt signaling	comment:mint	figure legend:F3B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/07	2014/10/16	rogid:ach7fn3ORk+raay2+9hHm6BmgyY8355	rogid:9er9svOSkPpB9x5tUpNuGMHWb7s8355	intact-crc:90A5695B82D94D78|rigid:XaaCCePvddvKxE+oO1ek/kY3lOs	false	-	glutathione s tranferase tag:?-?(MINT-4979399)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q90ZB6	uniprotkb:Q7T103	intact:EBI-7439087|intact:MINT-4979333|uniprotkb:Q6DD63	intact:EBI-7438970|uniprotkb:A9CDQ2|intact:MINT-4979275|uniprotkb:Q99293	psi-mi:t7l1b_xenla(display_long)|uniprotkb:tcf7l1-b(gene name)|psi-mi:tcf7l1-b(display_short)|uniprotkb:HMG box transcription factor 3-B(gene name synonym)|uniprotkb:tcf3(gene name synonym)|uniprotkb:tcf3b(gene name synonym)	psi-mi:p5f11_xenla(display_long)|uniprotkb:oct-25(gene name synonym)|uniprotkb:pou5f1.1(gene name)|psi-mi:pou5f1.1(display_short)|uniprotkb:POU class V protein oct-25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Cao et al. (2007)	pubmed:17541407|imex:IM-10834|mint:MINT-5219975	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7439148|mint:MINT-4979361|imex:IM-10834-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q90ZB6|interpro:IPR024940|refseq:NP_001080938.1|interpro:IPR027397|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR009071(High mobility group box, HMG)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR036910|interpro:IPR028778|mint:MINT-4979367(identity)	mint:Q7T103|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|refseq:NP_001079832.1|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR013847(POU)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007369"(gastrulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|mint:MINT-4979362(identity)	-	comment:mint|function:Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of ctnnb1-A and possibly ctnnb1-B, and as an activator in the presence of these proteins. Required early in development for the establishment of the dorsal body axis in response to maternal Wnt signaling	comment:mint	figure legend:F3A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/07	2014/10/16	rogid:ach7fn3ORk+raay2+9hHm6BmgyY8355	rogid:1W55S33qOMdyucj4w1befdCOH+08355	intact-crc:1E577C2F8C66F3F6|rigid:6HRaKHesam5KdUWT3u00ePj5Y0A	false	glutathione s tranferase tag:?-?(MINT-4979372)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P87377	uniprotkb:A1Y9B6	intact:EBI-7439000|uniprotkb:B7ZS85|uniprotkb:P87386|intact:MINT-4979289|uniprotkb:B1H1N4|uniprotkb:A2BDB3|uniprotkb:P79930	intact:EBI-7439163|intact:MINT-4979385	psi-mi:vegta_xenla(display_long)|uniprotkb:vegt-a(gene name)|psi-mi:vegt-a(display_short)|uniprotkb:Brachyury and Tbx-related protein(gene name synonym)|uniprotkb:T-box protein Antipodean(gene name synonym)|uniprotkb:apod(gene name synonym)|uniprotkb:brat(gene name synonym)|uniprotkb:vegt(gene name synonym)	psi-mi:a1y9b6_xenla(display_long)|uniprotkb:Oct60(gene name)|psi-mi:Oct60(display_short)	psi-mi:"MI:0096"(pull down)	Cao et al. (2007)	pubmed:17541407|imex:IM-10834|mint:MINT-5219975	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7439170|mint:MINT-4979375|imex:IM-10834-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P87377|refseq:XP_018088382.1|interpro:IPR018186|refseq:NP_001081665.1|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR001699(Transcription factor, T-box)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR036960|mint:MINT-4979381(identity)	mint:A1Y9B6|mint:MINT-4979376(identity)	-	comment:mint|function:Transcription factor involved in mesodermal patterning. Appears to pattern mesoderm along the dorsoventral and posterior axis. It activates WNT-8, EOMES and brachyury expression	comment:"fragmentation type: fragment"|comment:mint	figure legend:F3B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/07	2014/10/16	rogid:Fprh3NdbFqyzEK1Fq7c4nYqOII88355	rogid:QLzMKsmW/Z6D9nMt055AzBdDYxY8355	intact-crc:47A19ABE4C468E86|rigid:lphwE8hXvGUysNDpKYFno0uYIFA	false	-	glutathione s tranferase tag:?-?(MINT-4979378)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P87377	uniprotkb:B7ZQA9	intact:EBI-7439000|uniprotkb:B7ZS85|uniprotkb:P87386|intact:MINT-4979289|uniprotkb:B1H1N4|uniprotkb:A2BDB3|uniprotkb:P79930	intact:EBI-7439185|intact:MINT-4979404|uniprotkb:Q03917|uniprotkb:Q9PSI7	psi-mi:vegta_xenla(display_long)|uniprotkb:vegt-a(gene name)|psi-mi:vegt-a(display_short)|uniprotkb:Brachyury and Tbx-related protein(gene name synonym)|uniprotkb:T-box protein Antipodean(gene name synonym)|uniprotkb:apod(gene name synonym)|uniprotkb:brat(gene name synonym)|uniprotkb:vegt(gene name synonym)	psi-mi:p5f12_xenla(display_long)|uniprotkb:oct-91(gene name synonym)|uniprotkb:POU class V protein oct-91(gene name synonym)|uniprotkb:pou5f1.2(gene name)|psi-mi:pou5f1.2(display_short)	psi-mi:"MI:0096"(pull down)	Cao et al. (2007)	pubmed:17541407|imex:IM-10834|mint:MINT-5219975	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7439221|mint:MINT-4979418|imex:IM-10834-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P87377|refseq:XP_018088382.1|interpro:IPR018186|refseq:NP_001081665.1|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR001699(Transcription factor, T-box)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR036960|mint:MINT-4979419(identity)	mint:B7ZQA9|refseq:NP_001081342.1|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR013847(POU)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007369"(gastrulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|mint:MINT-4979422(identity)	-	comment:mint|function:Transcription factor involved in mesodermal patterning. Appears to pattern mesoderm along the dorsoventral and posterior axis. It activates WNT-8, EOMES and brachyury expression	comment:mint	figure legend:F3B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/07	2014/10/16	rogid:Fprh3NdbFqyzEK1Fq7c4nYqOII88355	rogid:9er9svOSkPpB9x5tUpNuGMHWb7s8355	intact-crc:B1AD35B0B2F208BC|rigid:eSJ6NKGS/QHW2FdWkIiKNWfegVY	false	-	glutathione s tranferase tag:?-?(MINT-4979424)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q90ZB6	uniprotkb:A1Y9B6	intact:EBI-7439087|intact:MINT-4979333|uniprotkb:Q6DD63	intact:EBI-7439163|intact:MINT-4979385	psi-mi:t7l1b_xenla(display_long)|uniprotkb:tcf7l1-b(gene name)|psi-mi:tcf7l1-b(display_short)|uniprotkb:HMG box transcription factor 3-B(gene name synonym)|uniprotkb:tcf3(gene name synonym)|uniprotkb:tcf3b(gene name synonym)	psi-mi:a1y9b6_xenla(display_long)|uniprotkb:Oct60(gene name)|psi-mi:Oct60(display_short)	psi-mi:"MI:0096"(pull down)	Cao et al. (2007)	pubmed:17541407|imex:IM-10834|mint:MINT-5219975	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7439252|mint:MINT-4979428|imex:IM-10834-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q90ZB6|interpro:IPR024940|refseq:NP_001080938.1|interpro:IPR027397|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR009071(High mobility group box, HMG)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR036910|interpro:IPR028778|mint:MINT-4979429(identity)	mint:A1Y9B6|mint:MINT-4979432(identity)	-	comment:mint|function:Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of ctnnb1-A and possibly ctnnb1-B, and as an activator in the presence of these proteins. Required early in development for the establishment of the dorsal body axis in response to maternal Wnt signaling	comment:"fragmentation type: fragment"|comment:mint	figure legend:F3B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/07	2014/10/16	rogid:ach7fn3ORk+raay2+9hHm6BmgyY8355	rogid:QLzMKsmW/Z6D9nMt055AzBdDYxY8355	intact-crc:66A9C6557C6DCB42|rigid:6DG29ISPqhXoICtVcsbsr5+m0lI	false	-	glutathione s tranferase tag:?-?(MINT-4979433)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P87377	uniprotkb:Q90ZB6	intact:EBI-7439000|uniprotkb:B7ZS85|uniprotkb:P87386|intact:MINT-4979289|uniprotkb:B1H1N4|uniprotkb:A2BDB3|uniprotkb:P79930	intact:EBI-7439087|intact:MINT-4979333|uniprotkb:Q6DD63	psi-mi:vegta_xenla(display_long)|uniprotkb:vegt-a(gene name)|psi-mi:vegt-a(display_short)|uniprotkb:Brachyury and Tbx-related protein(gene name synonym)|uniprotkb:T-box protein Antipodean(gene name synonym)|uniprotkb:apod(gene name synonym)|uniprotkb:brat(gene name synonym)|uniprotkb:vegt(gene name synonym)	psi-mi:t7l1b_xenla(display_long)|uniprotkb:tcf7l1-b(gene name)|psi-mi:tcf7l1-b(display_short)|uniprotkb:HMG box transcription factor 3-B(gene name synonym)|uniprotkb:tcf3(gene name synonym)|uniprotkb:tcf3b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Cao et al. (2007)	pubmed:17541407|imex:IM-10834|mint:MINT-5219975	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7439287|mint:MINT-4979457|imex:IM-10834-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P87377|refseq:XP_018088382.1|interpro:IPR018186|refseq:NP_001081665.1|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR001699(Transcription factor, T-box)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR036960|mint:MINT-4979465(identity)	mint:Q90ZB6|interpro:IPR024940|refseq:NP_001080938.1|interpro:IPR027397|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR009071(High mobility group box, HMG)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR036910|interpro:IPR028778|mint:MINT-4979458(identity)	-	comment:mint|function:Transcription factor involved in mesodermal patterning. Appears to pattern mesoderm along the dorsoventral and posterior axis. It activates WNT-8, EOMES and brachyury expression	comment:mint|function:Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of ctnnb1-A and possibly ctnnb1-B, and as an activator in the presence of these proteins. Required early in development for the establishment of the dorsal body axis in response to maternal Wnt signaling	figure legend:F3C|figure legend:F3D|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/07	2014/10/16	rogid:Fprh3NdbFqyzEK1Fq7c4nYqOII88355	rogid:ach7fn3ORk+raay2+9hHm6BmgyY8355	intact-crc:E68B0247E763E51E|rigid:VkxumXG5M/gUerMPCsQI1gyF938	false	glutathione s tranferase tag:?-?(MINT-4979470)|binding-associated region:1-230(MINT-4979472)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q90ZB6	uniprotkb:P87377	intact:EBI-7439087|intact:MINT-4979333|uniprotkb:Q6DD63	intact:EBI-7439000|uniprotkb:B7ZS85|uniprotkb:P87386|intact:MINT-4979289|uniprotkb:B1H1N4|uniprotkb:A2BDB3|uniprotkb:P79930	psi-mi:t7l1b_xenla(display_long)|uniprotkb:tcf7l1-b(gene name)|psi-mi:tcf7l1-b(display_short)|uniprotkb:HMG box transcription factor 3-B(gene name synonym)|uniprotkb:tcf3(gene name synonym)|uniprotkb:tcf3b(gene name synonym)	psi-mi:vegta_xenla(display_long)|uniprotkb:vegt-a(gene name)|psi-mi:vegt-a(display_short)|uniprotkb:Brachyury and Tbx-related protein(gene name synonym)|uniprotkb:T-box protein Antipodean(gene name synonym)|uniprotkb:apod(gene name synonym)|uniprotkb:brat(gene name synonym)|uniprotkb:vegt(gene name synonym)	psi-mi:"MI:0096"(pull down)	Cao et al. (2007)	pubmed:17541407|imex:IM-10834|mint:MINT-5219975	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7439316|mint:MINT-5209829|imex:IM-10834-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q90ZB6|interpro:IPR024940|refseq:NP_001080938.1|interpro:IPR027397|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR009071(High mobility group box, HMG)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR036910|interpro:IPR028778|mint:MINT-5209830(identity)	mint:P87377|refseq:XP_018088382.1|interpro:IPR018186|refseq:NP_001081665.1|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR001699(Transcription factor, T-box)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR036960|mint:MINT-5209836(identity)	-	comment:mint|function:Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of ctnnb1-A and possibly ctnnb1-B, and as an activator in the presence of these proteins. Required early in development for the establishment of the dorsal body axis in response to maternal Wnt signaling	comment:mint|function:Transcription factor involved in mesodermal patterning. Appears to pattern mesoderm along the dorsoventral and posterior axis. It activates WNT-8, EOMES and brachyury expression	figure legend:F3C|figure legend:F3D|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/07	2014/10/16	rogid:ach7fn3ORk+raay2+9hHm6BmgyY8355	rogid:Fprh3NdbFqyzEK1Fq7c4nYqOII88355	intact-crc:BE382689330F3B88|rigid:VkxumXG5M/gUerMPCsQI1gyF938	false	binding-associated region:398-551(MINT-5209831)|glutathione s tranferase tag:?-?(MINT-5209833)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P87377	uniprotkb:Q90ZB6	intact:EBI-7439000|uniprotkb:B7ZS85|uniprotkb:P87386|intact:MINT-4979289|uniprotkb:B1H1N4|uniprotkb:A2BDB3|uniprotkb:P79930	intact:EBI-7439087|intact:MINT-4979333|uniprotkb:Q6DD63	psi-mi:vegta_xenla(display_long)|uniprotkb:vegt-a(gene name)|psi-mi:vegt-a(display_short)|uniprotkb:Brachyury and Tbx-related protein(gene name synonym)|uniprotkb:T-box protein Antipodean(gene name synonym)|uniprotkb:apod(gene name synonym)|uniprotkb:brat(gene name synonym)|uniprotkb:vegt(gene name synonym)	psi-mi:t7l1b_xenla(display_long)|uniprotkb:tcf7l1-b(gene name)|psi-mi:tcf7l1-b(display_short)|uniprotkb:HMG box transcription factor 3-B(gene name synonym)|uniprotkb:tcf3(gene name synonym)|uniprotkb:tcf3b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Cao et al. (2007)	pubmed:17541407|imex:IM-10834|mint:MINT-5219975	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7439267|mint:MINT-4979440|imex:IM-10834-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:P87377|refseq:XP_018088382.1|interpro:IPR018186|refseq:NP_001081665.1|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR001699(Transcription factor, T-box)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR036960|mint:MINT-4979441(identity)	mint:Q90ZB6|interpro:IPR024940|refseq:NP_001080938.1|interpro:IPR027397|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR009071(High mobility group box, HMG)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR036910|interpro:IPR028778|mint:MINT-4979444(identity)	-	comment:mint|function:Transcription factor involved in mesodermal patterning. Appears to pattern mesoderm along the dorsoventral and posterior axis. It activates WNT-8, EOMES and brachyury expression	comment:mint|function:Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of ctnnb1-A and possibly ctnnb1-B, and as an activator in the presence of these proteins. Required early in development for the establishment of the dorsal body axis in response to maternal Wnt signaling	figure legend:F3C|figure legend:F3D|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/09/07	2014/10/16	rogid:Fprh3NdbFqyzEK1Fq7c4nYqOII88355	rogid:ach7fn3ORk+raay2+9hHm6BmgyY8355	intact-crc:0D8FFC32C7F4926D|rigid:VkxumXG5M/gUerMPCsQI1gyF938	false	-	glutathione s tranferase tag:?-?(MINT-4979446)|binding-associated region:191-397(MINT-4979451)	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7T103	uniprotkb:P87377	intact:EBI-7438970|uniprotkb:A9CDQ2|intact:MINT-4979275|uniprotkb:Q99293	intact:EBI-7439000|uniprotkb:B7ZS85|uniprotkb:P87386|intact:MINT-4979289|uniprotkb:B1H1N4|uniprotkb:A2BDB3|uniprotkb:P79930	psi-mi:p5f11_xenla(display_long)|uniprotkb:oct-25(gene name synonym)|uniprotkb:pou5f1.1(gene name)|psi-mi:pou5f1.1(display_short)|uniprotkb:POU class V protein oct-25(gene name synonym)	psi-mi:vegta_xenla(display_long)|uniprotkb:vegt-a(gene name)|psi-mi:vegt-a(display_short)|uniprotkb:Brachyury and Tbx-related protein(gene name synonym)|uniprotkb:T-box protein Antipodean(gene name synonym)|uniprotkb:apod(gene name synonym)|uniprotkb:brat(gene name synonym)|uniprotkb:vegt(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2007)	pubmed:17541407|imex:IM-10834|mint:MINT-5219975	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7439370|mint:MINT-4979499|imex:IM-10834-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q7T103|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|refseq:NP_001079832.1|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR013847(POU)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007369"(gastrulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|mint:MINT-4979500(identity)	mint:P87377|refseq:XP_018088382.1|interpro:IPR018186|refseq:NP_001081665.1|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR001699(Transcription factor, T-box)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR036960|mint:MINT-4979506(identity)	-	comment:mint	comment:mint|function:Transcription factor involved in mesodermal patterning. Appears to pattern mesoderm along the dorsoventral and posterior axis. It activates WNT-8, EOMES and brachyury expression	figure legend:F3E|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:8355(xenla-embryo)|taxid:8355(Xenopus laevis embryo)	-	2007/09/07	2014/10/16	rogid:1W55S33qOMdyucj4w1befdCOH+08355	rogid:Fprh3NdbFqyzEK1Fq7c4nYqOII88355	intact-crc:76A3388369D933FE|rigid:vXHM1BOvhBoRvmNidmnu1uT3WVc	false	-	myc tag:?-?(MINT-4979508)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q90ZB6	uniprotkb:P87377	intact:EBI-7439087|intact:MINT-4979333|uniprotkb:Q6DD63	intact:EBI-7439000|uniprotkb:B7ZS85|uniprotkb:P87386|intact:MINT-4979289|uniprotkb:B1H1N4|uniprotkb:A2BDB3|uniprotkb:P79930	psi-mi:t7l1b_xenla(display_long)|uniprotkb:tcf7l1-b(gene name)|psi-mi:tcf7l1-b(display_short)|uniprotkb:HMG box transcription factor 3-B(gene name synonym)|uniprotkb:tcf3(gene name synonym)|uniprotkb:tcf3b(gene name synonym)	psi-mi:vegta_xenla(display_long)|uniprotkb:vegt-a(gene name)|psi-mi:vegt-a(display_short)|uniprotkb:Brachyury and Tbx-related protein(gene name synonym)|uniprotkb:T-box protein Antipodean(gene name synonym)|uniprotkb:apod(gene name synonym)|uniprotkb:brat(gene name synonym)|uniprotkb:vegt(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2007)	pubmed:17541407|imex:IM-10834|mint:MINT-5219975	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7439352|mint:MINT-4979475|imex:IM-10834-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q90ZB6|interpro:IPR024940|refseq:NP_001080938.1|interpro:IPR027397|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR009071(High mobility group box, HMG)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR036910|interpro:IPR028778|mint:MINT-4979476(identity)	mint:P87377|refseq:XP_018088382.1|interpro:IPR018186|refseq:NP_001081665.1|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR001699(Transcription factor, T-box)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR036960|mint:MINT-4979479(identity)	-	comment:mint|function:Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of ctnnb1-A and possibly ctnnb1-B, and as an activator in the presence of these proteins. Required early in development for the establishment of the dorsal body axis in response to maternal Wnt signaling	comment:mint|function:Transcription factor involved in mesodermal patterning. Appears to pattern mesoderm along the dorsoventral and posterior axis. It activates WNT-8, EOMES and brachyury expression	figure legend:F3E|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:8355(xenla-embryo)|taxid:8355(Xenopus laevis embryo)	-	2007/09/07	2014/10/16	rogid:ach7fn3ORk+raay2+9hHm6BmgyY8355	rogid:Fprh3NdbFqyzEK1Fq7c4nYqOII88355	intact-crc:7E6AD43EB45F2554|rigid:VkxumXG5M/gUerMPCsQI1gyF938	false	flag tag:?-?(MINT-4979490)	myc tag:?-?(MINT-4979483)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7T103	uniprotkb:Q90ZB6	intact:EBI-7438970|uniprotkb:A9CDQ2|intact:MINT-4979275|uniprotkb:Q99293	intact:EBI-7439087|intact:MINT-4979333|uniprotkb:Q6DD63	psi-mi:p5f11_xenla(display_long)|uniprotkb:oct-25(gene name synonym)|uniprotkb:pou5f1.1(gene name)|psi-mi:pou5f1.1(display_short)|uniprotkb:POU class V protein oct-25(gene name synonym)	psi-mi:t7l1b_xenla(display_long)|uniprotkb:tcf7l1-b(gene name)|psi-mi:tcf7l1-b(display_short)|uniprotkb:HMG box transcription factor 3-B(gene name synonym)|uniprotkb:tcf3(gene name synonym)|uniprotkb:tcf3b(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Cao et al. (2007)	pubmed:17541407|imex:IM-10834|mint:MINT-5219975	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	taxid:8355(xenla)|taxid:8355("Xenopus laevis (African clawed frog)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7439385|mint:MINT-4979517|imex:IM-10834-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q7T103|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|refseq:NP_001079832.1|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR000327(POU-specific)|interpro:IPR001356(Homeobox)|interpro:IPR013847(POU)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007369"(gastrulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|mint:MINT-4979518(identity)	mint:Q90ZB6|interpro:IPR024940|refseq:NP_001080938.1|interpro:IPR027397|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR009071(High mobility group box, HMG)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR036910|interpro:IPR028778|mint:MINT-4979522(identity)	-	comment:mint	comment:mint|function:Participates in the Wnt signaling pathway. Binds to DNA and acts as a repressor in the absence of ctnnb1-A and possibly ctnnb1-B, and as an activator in the presence of these proteins. Required early in development for the establishment of the dorsal body axis in response to maternal Wnt signaling	figure legend:F3E|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:8355(xenla-embryo)|taxid:8355(Xenopus laevis embryo)	-	2007/09/07	2014/10/16	rogid:1W55S33qOMdyucj4w1befdCOH+08355	rogid:ach7fn3ORk+raay2+9hHm6BmgyY8355	intact-crc:D5EA5F68C44D01B1|rigid:6HRaKHesam5KdUWT3u00ePj5Y0A	false	-	myc tag:?-?(MINT-4979524)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)