#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9US25 uniprotkb:O59797 intact:EBI-7414005|uniprotkb:Q9UU28|intact:MINT-4979817|uniprotkb:Q92369|ensemblfungi:"SPAC1783.05.1:pep" intact:EBI-7414085|intact:MINT-4676253|ensemblfungi:"SPCC364.06.1:pep" psi-mi:hrp1_schpo(display_long)|uniprotkb:hrp1(gene name)|psi-mi:hrp1(display_short)|uniprotkb:SPAC1783.05(orf name)|uniprotkb:ATP-dependent helicase hrp1(gene name synonym) psi-mi:yco6_schpo(display_long)|uniprotkb:SPCC364.06(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Walfridsson et al. (2007) pubmed:17510629|imex:IM-11417|mint:MINT-5219938 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7414126|mint:MINT-4979848|imex:IM-11417-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9US25|interpro:IPR023780|interpro:IPR027417|interpro:IPR016197(Chromo domain-like)|refseq:NP_593660.1|ensemblfungi:SPAC1783.05(gene)|ensemblfungi:SPAC1783.05.1(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0043044"|go:"GO:0043486"(histone exchange)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR038718|mint:MINT-4979849(identity) mint:O59797|refseq:NP_587838.1|ensemblfungi:SPCC364.06(gene)|ensemblfungi:SPCC364.06.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:MINT-4979885(identity) - comment:mint|function:Seems to play a role in mitotic chromosome segregation and maintenance of chromatin structure. Has ATPase activity comment:mint figure legend:F1A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2007/09/10 2014/10/16 rogid:ZaqXCLF6Qn+gUCMcOyKnJaa72OU284812 rogid:HCs7j3t4WdtdvJZLXjzdFBIgkB4284812 intact-crc:4B425FBECD6DCED5|rigid:eKkrX//Anw+96gL2vnYyTFqd3Bw false flag tag:?-?(MINT-4979862) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9US25 uniprotkb:O14139 intact:EBI-7414005|uniprotkb:Q9UU28|intact:MINT-4979817|uniprotkb:Q92369|ensemblfungi:"SPAC1783.05.1:pep" intact:EBI-7414157|intact:MINT-4670837|ensemblfungi:"SPAC3G6.01.1:pep" psi-mi:hrp1_schpo(display_long)|uniprotkb:hrp1(gene name)|psi-mi:hrp1(display_short)|uniprotkb:SPAC1783.05(orf name)|uniprotkb:ATP-dependent helicase hrp1(gene name synonym) psi-mi:hrp3_schpo(display_long)|uniprotkb:hrp3(gene name)|psi-mi:hrp3(display_short)|uniprotkb:SPAC3G6.01(orf name)|uniprotkb:ATP-dependent helicase hrp3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Walfridsson et al. (2007) pubmed:17510629|imex:IM-11417|mint:MINT-5219938 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7414126|mint:MINT-4979848|imex:IM-11417-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9US25|interpro:IPR023780|interpro:IPR027417|interpro:IPR016197(Chromo domain-like)|refseq:NP_593660.1|ensemblfungi:SPAC1783.05(gene)|ensemblfungi:SPAC1783.05.1(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0043044"|go:"GO:0043486"(histone exchange)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR038718|mint:MINT-4979849(identity) mint:O14139|interpro:IPR025260|interpro:IPR027417|interpro:IPR023780|refseq:NP_594967.1|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|ensemblfungi:SPAC3G6.01(gene)|ensemblfungi:SPAC3G6.01.1(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070615"|go:"GO:0034728"(nucleosome organization)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR038718|interpro:IPR041150|mint:MINT-4979850(identity) - comment:mint|function:Seems to play a role in mitotic chromosome segregation and maintenance of chromatin structure. Has ATPase activity comment:mint|function:Involved in heterochromatin silencing. Required for transcriptional repression at the silence loci of mat3, where it has a direct role as a chromatin remodeling factor figure legend:F1A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2007/09/10 2014/10/16 rogid:ZaqXCLF6Qn+gUCMcOyKnJaa72OU284812 rogid:dgbVo9uyYXv6M/ADGjV00/fPU54284812 intact-crc:4B425FBECD6DCED5|rigid:eKkrX//Anw+96gL2vnYyTFqd3Bw false flag tag:?-?(MINT-4979862) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9US25 uniprotkb:O94236 intact:EBI-7414005|uniprotkb:Q9UU28|intact:MINT-4979817|uniprotkb:Q92369|ensemblfungi:"SPAC1783.05.1:pep" intact:EBI-7414101|intact:MINT-1542843 psi-mi:hrp1_schpo(display_long)|uniprotkb:hrp1(gene name)|psi-mi:hrp1(display_short)|uniprotkb:SPAC1783.05(orf name)|uniprotkb:ATP-dependent helicase hrp1(gene name synonym) psi-mi:eif3d_schpo(display_long)|uniprotkb:moe1(gene name)|psi-mi:moe1(display_short)|uniprotkb:SPAC637.07(orf name)|uniprotkb:eif3d(gene name synonym)|uniprotkb:Microtubule-destabilizing protein moe1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Walfridsson et al. (2007) pubmed:17510629|imex:IM-11417|mint:MINT-5219938 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7414126|mint:MINT-4979848|imex:IM-11417-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9US25|interpro:IPR023780|interpro:IPR027417|interpro:IPR016197(Chromo domain-like)|refseq:NP_593660.1|ensemblfungi:SPAC1783.05(gene)|ensemblfungi:SPAC1783.05.1(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0043044"|go:"GO:0043486"(histone exchange)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR038718|mint:MINT-4979849(identity) mint:O94236|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0098808"(mRNA cap binding)|reactome:R-SPO-156827|reactome:R-SPO-72649|reactome:R-SPO-72689|reactome:R-SPO-72695|reactome:R-SPO-72702|reactome:R-SPO-72706|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|refseq:NP_594625.1|mint:MINT-4979854(identity) - comment:mint|function:Seems to play a role in mitotic chromosome segregation and maintenance of chromatin structure. Has ATPase activity comment:mint|function:Binds to the 40S ribosome. Induces instabilty in microtubules. Affect spingle formation figure legend:F1A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2007/09/10 2014/10/16 rogid:ZaqXCLF6Qn+gUCMcOyKnJaa72OU284812 rogid:V0sI7glDxgcBkQ3BUz+CHW9D4pg284812 intact-crc:4B425FBECD6DCED5|rigid:eKkrX//Anw+96gL2vnYyTFqd3Bw false flag tag:?-?(MINT-4979862) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9US25 uniprotkb:O43030 intact:EBI-7414005|uniprotkb:Q9UU28|intact:MINT-4979817|uniprotkb:Q92369|ensemblfungi:"SPAC1783.05.1:pep" intact:EBI-7414040|intact:MINT-4674747|ensemblfungi:"SPBC3B9.01.1:pep" psi-mi:hrp1_schpo(display_long)|uniprotkb:hrp1(gene name)|psi-mi:hrp1(display_short)|uniprotkb:SPAC1783.05(orf name)|uniprotkb:ATP-dependent helicase hrp1(gene name synonym) psi-mi:fes1_schpo(display_long)|uniprotkb:fes1(gene name)|psi-mi:fes1(display_short)|uniprotkb:SPBC3B9.01(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Walfridsson et al. (2007) pubmed:17510629|imex:IM-11417|mint:MINT-5219938 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7414126|mint:MINT-4979848|imex:IM-11417-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9US25|interpro:IPR023780|interpro:IPR027417|interpro:IPR016197(Chromo domain-like)|refseq:NP_593660.1|ensemblfungi:SPAC1783.05(gene)|ensemblfungi:SPAC1783.05.1(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0043044"|go:"GO:0043486"(histone exchange)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR038718|mint:MINT-4979849(identity) mint:O43030|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_596658.1|ensemblfungi:SPBC3B9.01(gene)|ensemblfungi:SPBC3B9.01.1(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0071629"(cytoplasm protein quality control by the ubiquitin-proteasome system)|interpro:IPR013918(Nucleotide exchange factor Fes1)|mint:MINT-4979934(identity) - comment:mint|function:Seems to play a role in mitotic chromosome segregation and maintenance of chromatin structure. Has ATPase activity comment:mint|function:"Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins" figure legend:F1A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2007/09/10 2014/10/16 rogid:ZaqXCLF6Qn+gUCMcOyKnJaa72OU284812 rogid:6cBs2KdUYf8vio93cS43JzMN1sY284812 intact-crc:4B425FBECD6DCED5|rigid:eKkrX//Anw+96gL2vnYyTFqd3Bw false flag tag:?-?(MINT-4979862) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9US25 uniprotkb:P78795 intact:EBI-7414005|uniprotkb:Q9UU28|intact:MINT-4979817|uniprotkb:Q92369|ensemblfungi:"SPAC1783.05.1:pep" intact:EBI-7414057|intact:MINT-4691268|ensemblfungi:"SPBC18H10.03.1:pep" psi-mi:hrp1_schpo(display_long)|uniprotkb:hrp1(gene name)|psi-mi:hrp1(display_short)|uniprotkb:SPAC1783.05(orf name)|uniprotkb:ATP-dependent helicase hrp1(gene name synonym) psi-mi:eif3g_schpo(display_long)|uniprotkb:tif35(gene name)|psi-mi:tif35(display_short)|uniprotkb:SPBC18H10.03(orf name)|uniprotkb:eif3g(gene name synonym)|uniprotkb:Translation initiation factor eIF3 p33 subunit homolog(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 RNA-binding subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Walfridsson et al. (2007) pubmed:17510629|imex:IM-11417|mint:MINT-5219938 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7414126|mint:MINT-4979848|imex:IM-11417-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9US25|interpro:IPR023780|interpro:IPR027417|interpro:IPR016197(Chromo domain-like)|refseq:NP_593660.1|ensemblfungi:SPAC1783.05(gene)|ensemblfungi:SPAC1783.05.1(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0043044"|go:"GO:0043486"(histone exchange)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR038718|mint:MINT-4979849(identity) mint:P78795|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034240|refseq:NP_595727.1|interpro:IPR024675|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|ensemblfungi:SPBC18H10.03(gene)|ensemblfungi:SPBC18H10.03.1(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|reactome:R-SPO-156827|reactome:R-SPO-72649|reactome:R-SPO-72689|reactome:R-SPO-72695|reactome:R-SPO-72702|reactome:R-SPO-72706|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979|mint:MINT-4979851(identity) - comment:mint|function:Seems to play a role in mitotic chromosome segregation and maintenance of chromatin structure. Has ATPase activity function:Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA. This subunit binds to the 18S rRNA|comment:mint figure legend:F1A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2007/09/10 2014/10/16 rogid:ZaqXCLF6Qn+gUCMcOyKnJaa72OU284812 rogid:dkNkdzFDXaiD5f0F1dOYTyMWKQY284812 intact-crc:4B425FBECD6DCED5|rigid:eKkrX//Anw+96gL2vnYyTFqd3Bw false flag tag:?-?(MINT-4979862) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9US25 uniprotkb:O94267 intact:EBI-7414005|uniprotkb:Q9UU28|intact:MINT-4979817|uniprotkb:Q92369|ensemblfungi:"SPAC1783.05.1:pep" intact:EBI-7414132|intact:MINT-4682716|ensemblfungi:"SPBP8B7.19.1:pep" psi-mi:hrp1_schpo(display_long)|uniprotkb:hrp1(gene name)|psi-mi:hrp1(display_short)|uniprotkb:SPAC1783.05(orf name)|uniprotkb:ATP-dependent helicase hrp1(gene name synonym) psi-mi:spt16_schpo(display_long)|uniprotkb:spt16(gene name)|psi-mi:spt16(display_short)|uniprotkb:SPBP8B7.19(orf name)|uniprotkb:Facilitates chromatin transcription complex subunit spt16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Walfridsson et al. (2007) pubmed:17510629|imex:IM-11417|mint:MINT-5219938 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7414126|mint:MINT-4979848|imex:IM-11417-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9US25|interpro:IPR023780|interpro:IPR027417|interpro:IPR016197(Chromo domain-like)|refseq:NP_593660.1|ensemblfungi:SPAC1783.05(gene)|ensemblfungi:SPAC1783.05.1(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0043044"|go:"GO:0043486"(histone exchange)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR038718|mint:MINT-4979849(identity) mint:O94267|refseq:NP_596526.1|ensemblfungi:SPBP8B7.19(gene)|ensemblfungi:SPBP8B7.19.1(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|go:"GO:0043486"(histone exchange)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|interpro:IPR029148|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|rcsb pdb:3CB5|rcsb pdb:3CB6|reactome:R-SPO-674695|reactome:R-SPO-6796648|reactome:R-SPO-6804756|reactome:R-SPO-75955|dip:DIP-44081N|mint:MINT-4979852(identity) - comment:mint|function:Seems to play a role in mitotic chromosome segregation and maintenance of chromatin structure. Has ATPase activity crc64:50AD706DD6C03313|comment:mint|function:Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishement of the nucleosome following the passage of RNA polymerase II figure legend:F1A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2007/09/10 2014/10/16 rogid:ZaqXCLF6Qn+gUCMcOyKnJaa72OU284812 rogid:QBnU3xQr7DXuNLMiPyN/YcXva3U284812 intact-crc:4B425FBECD6DCED5|rigid:eKkrX//Anw+96gL2vnYyTFqd3Bw false flag tag:?-?(MINT-4979862) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9US25 uniprotkb:O74879 intact:EBI-7414005|uniprotkb:Q9UU28|intact:MINT-4979817|uniprotkb:Q92369|ensemblfungi:"SPAC1783.05.1:pep" intact:EBI-7413987|intact:MINT-4681509|ensemblfungi:"SPCC330.09.1:pep" psi-mi:hrp1_schpo(display_long)|uniprotkb:hrp1(gene name)|psi-mi:hrp1(display_short)|uniprotkb:SPAC1783.05(orf name)|uniprotkb:ATP-dependent helicase hrp1(gene name synonym) psi-mi:nol10_schpo(display_long)|uniprotkb:SPCC330.09(orf name)|uniprotkb:enp2(gene name)|psi-mi:enp2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Walfridsson et al. (2007) pubmed:17510629|imex:IM-11417|mint:MINT-5219938 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-7414126|mint:MINT-4979848|imex:IM-11417-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9US25|interpro:IPR023780|interpro:IPR027417|interpro:IPR016197(Chromo domain-like)|refseq:NP_593660.1|ensemblfungi:SPAC1783.05(gene)|ensemblfungi:SPAC1783.05.1(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0043044"|go:"GO:0043486"(histone exchange)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR038718|mint:MINT-4979849(identity) mint:O74879|refseq:NP_587709.1|interpro:IPR015943(WD40/YVTN repeat-like)|ensemblfungi:SPCC330.09(gene)|ensemblfungi:SPCC330.09.1(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0030686"(90S preribosome)|go:"GO:0032040"(small-subunit processome)|interpro:IPR001680(WD40 repeat)|interpro:IPR012580(NUC153)|interpro:IPR036322|interpro:IPR040382|mint:MINT-4979853(identity) - comment:mint|function:Seems to play a role in mitotic chromosome segregation and maintenance of chromatin structure. Has ATPase activity function:May be involved in rRNA-processing and ribosome biosynthesis|comment:mint figure legend:F1A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2007/09/10 2014/10/16 rogid:ZaqXCLF6Qn+gUCMcOyKnJaa72OU284812 rogid:fvgf5lCoB83X6ShZqvMtO2Rgbao284812 intact-crc:4B425FBECD6DCED5|rigid:eKkrX//Anw+96gL2vnYyTFqd3Bw false flag tag:?-?(MINT-4979862) - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O14139 uniprotkb:O59797 intact:EBI-7414157|intact:MINT-4670837|ensemblfungi:"SPAC3G6.01.1:pep" intact:EBI-7414085|intact:MINT-4676253|ensemblfungi:"SPCC364.06.1:pep" psi-mi:hrp3_schpo(display_long)|uniprotkb:hrp3(gene name)|psi-mi:hrp3(display_short)|uniprotkb:SPAC3G6.01(orf name)|uniprotkb:ATP-dependent helicase hrp3(gene name synonym) psi-mi:yco6_schpo(display_long)|uniprotkb:SPCC364.06(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Walfridsson et al. (2007) pubmed:17510629|imex:IM-11417|mint:MINT-5219938 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7414254|mint:MINT-4979939|imex:IM-11417-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:O14139|interpro:IPR025260|interpro:IPR027417|interpro:IPR023780|refseq:NP_594967.1|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|ensemblfungi:SPAC3G6.01(gene)|ensemblfungi:SPAC3G6.01.1(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031934"(mating-type region heterochromatin)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070615"|go:"GO:0034728"(nucleosome organization)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR038718|interpro:IPR041150|mint:MINT-4979946(identity) mint:O59797|refseq:NP_587838.1|ensemblfungi:SPCC364.06(gene)|ensemblfungi:SPCC364.06.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:MINT-4979940(identity) - comment:mint|function:Involved in heterochromatin silencing. Required for transcriptional repression at the silence loci of mat3, where it has a direct role as a chromatin remodeling factor comment:mint figure legend:F1C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2007/09/10 2014/10/16 rogid:dgbVo9uyYXv6M/ADGjV00/fPU54284812 rogid:HCs7j3t4WdtdvJZLXjzdFBIgkB4284812 intact-crc:11436D084600662D|rigid:giqj3cULzuuj6lPvIwkepbmJdDY false myc tag:?-?(MINT-4979947) calmodulin binding peptide plus protein a tag:?-?(MINT-4979942) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9US25 uniprotkb:O59797 intact:EBI-7414005|uniprotkb:Q9UU28|intact:MINT-4979817|uniprotkb:Q92369|ensemblfungi:"SPAC1783.05.1:pep" intact:EBI-7414085|intact:MINT-4676253|ensemblfungi:"SPCC364.06.1:pep" psi-mi:hrp1_schpo(display_long)|uniprotkb:hrp1(gene name)|psi-mi:hrp1(display_short)|uniprotkb:SPAC1783.05(orf name)|uniprotkb:ATP-dependent helicase hrp1(gene name synonym) psi-mi:yco6_schpo(display_long)|uniprotkb:SPCC364.06(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Walfridsson et al. (2007) pubmed:17510629|imex:IM-11417|mint:MINT-5219938 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7414236|mint:MINT-4979890|imex:IM-11417-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q9US25|interpro:IPR023780|interpro:IPR027417|interpro:IPR016197(Chromo domain-like)|refseq:NP_593660.1|ensemblfungi:SPAC1783.05(gene)|ensemblfungi:SPAC1783.05.1(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016787"(hydrolase activity)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0043044"|go:"GO:0043486"(histone exchange)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060303"(regulation of nucleosome density)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR038718|mint:MINT-4979895(identity) mint:O59797|refseq:NP_587838.1|ensemblfungi:SPCC364.06(gene)|ensemblfungi:SPCC364.06.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:MINT-4979917(identity) - comment:mint|function:Seems to play a role in mitotic chromosome segregation and maintenance of chromatin structure. Has ATPase activity comment:mint figure legend:F1C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") - 2007/09/10 2014/10/16 rogid:ZaqXCLF6Qn+gUCMcOyKnJaa72OU284812 rogid:HCs7j3t4WdtdvJZLXjzdFBIgkB4284812 intact-crc:70753860D8E1A006|rigid:RaZruFm5eQvGdKFEqzPFFVKQk1o false myc tag:?-?(MINT-4979898) calmodulin binding peptide plus protein a tag:?-?(MINT-4979930) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant)