#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P33076 uniprotkb:P98168 intact:EBI-1538819|uniprotkb:A0N0N9|uniprotkb:E9PFE0|uniprotkb:Q29675|uniprotkb:Q8SNB8|uniprotkb:Q96KL4|uniprotkb:D3DUG0 intact:EBI-1538980|uniprotkb:Q9UJP7|ensembl:ENSP00000351530 psi-mi:c2ta_human(display_long)|uniprotkb:CIITA(gene name)|psi-mi:CIITA(display_short)|uniprotkb:MHC2TA(gene name synonym) psi-mi:zxda_human(display_long)|uniprotkb:ZXDA(gene name)|psi-mi:ZXDA(display_short) psi-mi:"MI:0232"(transcriptional complementation assay) Al-Kandari et al. (2007) pubmed:17493635|imex:IM-19372 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1538988|imex:IM-19372-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000237.2|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR008095(MHC class II transactivator)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|reactome:R-HSA-877300|refseq:NP_001273332.1|interpro:IPR032675|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016605"(PML body)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046677"(response to antibiotic)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140297"(DNA-binding transcription factor binding) refseq:NP_009087.1|ensembl:ENSG00000198205(gene)|ensembl:ENST00000358697(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 - - - figure legend:4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/09/27 2014/10/16 rogid:olV8Tqn3hDJjyAbn6x/m5ncNoEA9606 rogid:Uqd5wElfmhvO3Be4kqxSXnxzSj09606 intact-crc:67AFE9752322413B|rigid:5zAczdwzPK+lLyWFXCAkdhs/wu4 false - sufficient binding region:271-799|tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P98168 uniprotkb:P33076 intact:EBI-1538980|uniprotkb:Q9UJP7|ensembl:ENSP00000351530 intact:EBI-1538819|uniprotkb:A0N0N9|uniprotkb:E9PFE0|uniprotkb:Q29675|uniprotkb:Q8SNB8|uniprotkb:Q96KL4|uniprotkb:D3DUG0 psi-mi:zxda_human(display_long)|uniprotkb:ZXDA(gene name)|psi-mi:ZXDA(display_short) psi-mi:c2ta_human(display_long)|uniprotkb:CIITA(gene name)|psi-mi:CIITA(display_short)|uniprotkb:MHC2TA(gene name synonym) psi-mi:"MI:0232"(transcriptional complementation assay) Al-Kandari et al. (2007) pubmed:17493635|imex:IM-19372 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1539039|imex:IM-19372-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009087.1|ensembl:ENSG00000198205(gene)|ensembl:ENST00000358697(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 refseq:NP_000237.2|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR008095(MHC class II transactivator)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|reactome:R-HSA-877300|refseq:NP_001273332.1|interpro:IPR032675|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016605"(PML body)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046677"(response to antibiotic)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140297"(DNA-binding transcription factor binding) - - - figure legend:7A|stimulant:This interaction requires or is facilitated by ZXDC.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/09/27 2014/10/16 rogid:Uqd5wElfmhvO3Be4kqxSXnxzSj09606 rogid:olV8Tqn3hDJjyAbn6x/m5ncNoEA9606 intact-crc:037FB0D4039A0F34|rigid:5zAczdwzPK+lLyWFXCAkdhs/wu4 false flag tag:n-n sufficient binding region:323-1130|tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q2QGD7 uniprotkb:P98168 intact:EBI-1538838|uniprotkb:Q7L3L1|uniprotkb:Q8NAU2|uniprotkb:C5J0H9|uniprotkb:Q6DKI8|ensembl:ENSP00000374359|intact:EBI-28981670 intact:EBI-1538980|uniprotkb:Q9UJP7|ensembl:ENSP00000351530 psi-mi:zxdc_human(display_long)|uniprotkb:ZXDC(gene name)|psi-mi:ZXDC(display_short)|uniprotkb:ZXDL(gene name synonym)|uniprotkb:ZXD-like zinc finger protein(gene name synonym) psi-mi:zxda_human(display_long)|uniprotkb:ZXDA(gene name)|psi-mi:ZXDA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Al-Kandari et al. (2007) pubmed:17493635|imex:IM-19372 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1539001|imex:IM-19372-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035743.1|refseq:NP_079388.3|ensembl:ENST00000336332|ensembl:ENSP00000337694|ensembl:ENSP00000374359|ensembl:ENSG00000070476(gene)|ensembl:ENST00000389709(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2QGD7 refseq:NP_009087.1|ensembl:ENSG00000198205(gene)|ensembl:ENST00000358697(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 - - - figure legend:5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/09/27 2014/10/16 rogid:2oqRV2O8vmW9f6FeX+td6cvhyNI9606 rogid:Uqd5wElfmhvO3Be4kqxSXnxzSj09606 intact-crc:82CBFE1300A916DA|rigid:t5dBmYDdbg+T/j5yogSottd0bps false ha tag:n-n flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q2QGD7 uniprotkb:Q2QGD7 intact:EBI-1538838|uniprotkb:Q7L3L1|uniprotkb:Q8NAU2|uniprotkb:C5J0H9|uniprotkb:Q6DKI8|ensembl:ENSP00000374359|intact:EBI-28981670 intact:EBI-1538838|uniprotkb:Q7L3L1|uniprotkb:Q8NAU2|uniprotkb:C5J0H9|uniprotkb:Q6DKI8|ensembl:ENSP00000374359|intact:EBI-28981670 psi-mi:zxdc_human(display_long)|uniprotkb:ZXDC(gene name)|psi-mi:ZXDC(display_short)|uniprotkb:ZXDL(gene name synonym)|uniprotkb:ZXD-like zinc finger protein(gene name synonym) psi-mi:zxdc_human(display_long)|uniprotkb:ZXDC(gene name)|psi-mi:ZXDC(display_short)|uniprotkb:ZXDL(gene name synonym)|uniprotkb:ZXD-like zinc finger protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Al-Kandari et al. (2007) pubmed:17493635|imex:IM-19372 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1539009|imex:IM-19372-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035743.1|refseq:NP_079388.3|ensembl:ENST00000336332|ensembl:ENSP00000337694|ensembl:ENSP00000374359|ensembl:ENSG00000070476(gene)|ensembl:ENST00000389709(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2QGD7 refseq:NP_001035743.1|refseq:NP_079388.3|ensembl:ENST00000336332|ensembl:ENSP00000337694|ensembl:ENSP00000374359|ensembl:ENSG00000070476(gene)|ensembl:ENST00000389709(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2QGD7 - - - figure legend:5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/09/27 2014/10/16 rogid:2oqRV2O8vmW9f6FeX+td6cvhyNI9606 rogid:2oqRV2O8vmW9f6FeX+td6cvhyNI9606 intact-crc:083016925AFE05F3|rigid:6Uno2/rBb6F+P/U00xhZv7/91c4 false ha tag:n-n flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P98168 uniprotkb:P98168 intact:EBI-1538980|uniprotkb:Q9UJP7|ensembl:ENSP00000351530 intact:EBI-1538980|uniprotkb:Q9UJP7|ensembl:ENSP00000351530 psi-mi:zxda_human(display_long)|uniprotkb:ZXDA(gene name)|psi-mi:ZXDA(display_short) psi-mi:zxda_human(display_long)|uniprotkb:ZXDA(gene name)|psi-mi:ZXDA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Al-Kandari et al. (2007) pubmed:17493635|imex:IM-19372 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1539017|imex:IM-19372-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009087.1|ensembl:ENSG00000198205(gene)|ensembl:ENST00000358697(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 refseq:NP_009087.1|ensembl:ENSG00000198205(gene)|ensembl:ENST00000358697(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 - - - figure legend:5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/09/27 2014/10/16 rogid:Uqd5wElfmhvO3Be4kqxSXnxzSj09606 rogid:Uqd5wElfmhvO3Be4kqxSXnxzSj09606 intact-crc:06B5A14CC0184361|rigid:jjb01Hl+SEoayghZcOopV6Q2Gk4 false myc tag:n-n flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q2QGD7 uniprotkb:P98168 intact:EBI-1538838|uniprotkb:Q7L3L1|uniprotkb:Q8NAU2|uniprotkb:C5J0H9|uniprotkb:Q6DKI8|ensembl:ENSP00000374359|intact:EBI-28981670 intact:EBI-1538980|uniprotkb:Q9UJP7|ensembl:ENSP00000351530 psi-mi:zxdc_human(display_long)|uniprotkb:ZXDC(gene name)|psi-mi:ZXDC(display_short)|uniprotkb:ZXDL(gene name synonym)|uniprotkb:ZXD-like zinc finger protein(gene name synonym) psi-mi:zxda_human(display_long)|uniprotkb:ZXDA(gene name)|psi-mi:ZXDA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Al-Kandari et al. (2007) pubmed:17493635|imex:IM-19372 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1539025|imex:IM-19372-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035743.1|refseq:NP_079388.3|ensembl:ENST00000336332|ensembl:ENSP00000337694|ensembl:ENSP00000374359|ensembl:ENSG00000070476(gene)|ensembl:ENST00000389709(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2QGD7 refseq:NP_009087.1|ensembl:ENSG00000198205(gene)|ensembl:ENST00000358697(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 - - - figure legend:6A, 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/09/27 2014/10/16 rogid:2oqRV2O8vmW9f6FeX+td6cvhyNI9606 rogid:Uqd5wElfmhvO3Be4kqxSXnxzSj09606 intact-crc:7058DCE126745F14|rigid:t5dBmYDdbg+T/j5yogSottd0bps false flag tag:n-n|binding-associated region:177-471 myc tag:n-n|sufficient binding region:1-573 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P98168 uniprotkb:P33076 intact:EBI-1538980|uniprotkb:Q9UJP7|ensembl:ENSP00000351530 intact:EBI-1538819|uniprotkb:A0N0N9|uniprotkb:E9PFE0|uniprotkb:Q29675|uniprotkb:Q8SNB8|uniprotkb:Q96KL4|uniprotkb:D3DUG0 psi-mi:zxda_human(display_long)|uniprotkb:ZXDA(gene name)|psi-mi:ZXDA(display_short) psi-mi:c2ta_human(display_long)|uniprotkb:CIITA(gene name)|psi-mi:CIITA(display_short)|uniprotkb:MHC2TA(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Al-Kandari et al. (2007) pubmed:17493635|imex:IM-19372 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1539059|imex:IM-19372-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009087.1|ensembl:ENSG00000198205(gene)|ensembl:ENST00000358697(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 refseq:NP_000237.2|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR008095(MHC class II transactivator)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|reactome:R-HSA-877300|refseq:NP_001273332.1|interpro:IPR032675|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016605"(PML body)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046677"(response to antibiotic)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140297"(DNA-binding transcription factor binding) - - - figure legend:7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/09/27 2014/10/16 rogid:Uqd5wElfmhvO3Be4kqxSXnxzSj09606 rogid:olV8Tqn3hDJjyAbn6x/m5ncNoEA9606 intact-crc:695CDA16059A5668|rigid:V/tKZGxxroGxs0RqFHLXMrrW3Lw false flag tag:n-n ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P98168 uniprotkb:Q2QGD7 intact:EBI-1538980|uniprotkb:Q9UJP7|ensembl:ENSP00000351530 intact:EBI-1538838|uniprotkb:Q7L3L1|uniprotkb:Q8NAU2|uniprotkb:C5J0H9|uniprotkb:Q6DKI8|ensembl:ENSP00000374359|intact:EBI-28981670 psi-mi:zxda_human(display_long)|uniprotkb:ZXDA(gene name)|psi-mi:ZXDA(display_short) psi-mi:zxdc_human(display_long)|uniprotkb:ZXDC(gene name)|psi-mi:ZXDC(display_short)|uniprotkb:ZXDL(gene name synonym)|uniprotkb:ZXD-like zinc finger protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Al-Kandari et al. (2007) pubmed:17493635|imex:IM-19372 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1539059|imex:IM-19372-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009087.1|ensembl:ENSG00000198205(gene)|ensembl:ENST00000358697(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 refseq:NP_001035743.1|refseq:NP_079388.3|ensembl:ENST00000336332|ensembl:ENSP00000337694|ensembl:ENSP00000374359|ensembl:ENSG00000070476(gene)|ensembl:ENST00000389709(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2QGD7 - - - figure legend:7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/09/27 2014/10/16 rogid:Uqd5wElfmhvO3Be4kqxSXnxzSj09606 rogid:2oqRV2O8vmW9f6FeX+td6cvhyNI9606 intact-crc:695CDA16059A5668|rigid:V/tKZGxxroGxs0RqFHLXMrrW3Lw false flag tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P98168 uniprotkb:P33076 intact:EBI-1538980|uniprotkb:Q9UJP7|ensembl:ENSP00000351530 intact:EBI-1538819|uniprotkb:A0N0N9|uniprotkb:E9PFE0|uniprotkb:Q29675|uniprotkb:Q8SNB8|uniprotkb:Q96KL4|uniprotkb:D3DUG0 psi-mi:zxda_human(display_long)|uniprotkb:ZXDA(gene name)|psi-mi:ZXDA(display_short) psi-mi:c2ta_human(display_long)|uniprotkb:CIITA(gene name)|psi-mi:CIITA(display_short)|uniprotkb:MHC2TA(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Al-Kandari et al. (2007) pubmed:17493635|imex:IM-19372 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1539106|imex:IM-19372-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009087.1|ensembl:ENSG00000198205(gene)|ensembl:ENST00000358697(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 refseq:NP_000237.2|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR008095(MHC class II transactivator)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|reactome:R-HSA-877300|refseq:NP_001273332.1|interpro:IPR032675|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016605"(PML body)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046677"(response to antibiotic)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140297"(DNA-binding transcription factor binding) - - - figure legend:8B|stimulant:Interaction between ZXDA and CIITA requires ZXDC.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/27 2014/10/16 rogid:Uqd5wElfmhvO3Be4kqxSXnxzSj09606 rogid:olV8Tqn3hDJjyAbn6x/m5ncNoEA9606 intact-crc:255B42936479AD54|rigid:V/tKZGxxroGxs0RqFHLXMrrW3Lw false myc tag:n-n ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P98168 uniprotkb:Q2QGD7 intact:EBI-1538980|uniprotkb:Q9UJP7|ensembl:ENSP00000351530 intact:EBI-1538838|uniprotkb:Q7L3L1|uniprotkb:Q8NAU2|uniprotkb:C5J0H9|uniprotkb:Q6DKI8|ensembl:ENSP00000374359|intact:EBI-28981670 psi-mi:zxda_human(display_long)|uniprotkb:ZXDA(gene name)|psi-mi:ZXDA(display_short) psi-mi:zxdc_human(display_long)|uniprotkb:ZXDC(gene name)|psi-mi:ZXDC(display_short)|uniprotkb:ZXDL(gene name synonym)|uniprotkb:ZXD-like zinc finger protein(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Al-Kandari et al. (2007) pubmed:17493635|imex:IM-19372 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1539106|imex:IM-19372-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009087.1|ensembl:ENSG00000198205(gene)|ensembl:ENST00000358697(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 refseq:NP_001035743.1|refseq:NP_079388.3|ensembl:ENST00000336332|ensembl:ENSP00000337694|ensembl:ENSP00000374359|ensembl:ENSG00000070476(gene)|ensembl:ENST00000389709(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2QGD7 - - - figure legend:8B|stimulant:Interaction between ZXDA and CIITA requires ZXDC.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/27 2014/10/16 rogid:Uqd5wElfmhvO3Be4kqxSXnxzSj09606 rogid:2oqRV2O8vmW9f6FeX+td6cvhyNI9606 intact-crc:255B42936479AD54|rigid:V/tKZGxxroGxs0RqFHLXMrrW3Lw false myc tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q2QGD7 uniprotkb:P98168 intact:EBI-1538838|uniprotkb:Q7L3L1|uniprotkb:Q8NAU2|uniprotkb:C5J0H9|uniprotkb:Q6DKI8|ensembl:ENSP00000374359|intact:EBI-28981670 intact:EBI-1538980|uniprotkb:Q9UJP7|ensembl:ENSP00000351530 psi-mi:zxdc_human(display_long)|uniprotkb:ZXDC(gene name)|psi-mi:ZXDC(display_short)|uniprotkb:ZXDL(gene name synonym)|uniprotkb:ZXD-like zinc finger protein(gene name synonym) psi-mi:zxda_human(display_long)|uniprotkb:ZXDA(gene name)|psi-mi:ZXDA(display_short) psi-mi:"MI:0019"(coimmunoprecipitation) Al-Kandari et al. (2007) pubmed:17493635|imex:IM-19372 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1539128|imex:IM-19372-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035743.1|refseq:NP_079388.3|ensembl:ENST00000336332|ensembl:ENSP00000337694|ensembl:ENSP00000374359|ensembl:ENSG00000070476(gene)|ensembl:ENST00000389709(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2QGD7 refseq:NP_009087.1|ensembl:ENSG00000198205(gene)|ensembl:ENST00000358697(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236 - - - figure legend:8C|stimulant:Interaction between ZXDC and CIITA requires ZXDA.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/27 2014/10/16 rogid:2oqRV2O8vmW9f6FeX+td6cvhyNI9606 rogid:Uqd5wElfmhvO3Be4kqxSXnxzSj09606 intact-crc:14E614ECCA990DA5|rigid:V/tKZGxxroGxs0RqFHLXMrrW3Lw false - myc tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q2QGD7 uniprotkb:P33076 intact:EBI-1538838|uniprotkb:Q7L3L1|uniprotkb:Q8NAU2|uniprotkb:C5J0H9|uniprotkb:Q6DKI8|ensembl:ENSP00000374359|intact:EBI-28981670 intact:EBI-1538819|uniprotkb:A0N0N9|uniprotkb:E9PFE0|uniprotkb:Q29675|uniprotkb:Q8SNB8|uniprotkb:Q96KL4|uniprotkb:D3DUG0 psi-mi:zxdc_human(display_long)|uniprotkb:ZXDC(gene name)|psi-mi:ZXDC(display_short)|uniprotkb:ZXDL(gene name synonym)|uniprotkb:ZXD-like zinc finger protein(gene name synonym) psi-mi:c2ta_human(display_long)|uniprotkb:CIITA(gene name)|psi-mi:CIITA(display_short)|uniprotkb:MHC2TA(gene name synonym) psi-mi:"MI:0019"(coimmunoprecipitation) Al-Kandari et al. (2007) pubmed:17493635|imex:IM-19372 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-1539128|imex:IM-19372-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001035743.1|refseq:NP_079388.3|ensembl:ENST00000336332|ensembl:ENSP00000337694|ensembl:ENSP00000374359|ensembl:ENSG00000070476(gene)|ensembl:ENST00000389709(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2QGD7 refseq:NP_000237.2|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR008095(MHC class II transactivator)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|reactome:R-HSA-877300|refseq:NP_001273332.1|interpro:IPR032675|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016605"(PML body)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046677"(response to antibiotic)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140297"(DNA-binding transcription factor binding) - - - figure legend:8C|stimulant:Interaction between ZXDC and CIITA requires ZXDA.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/09/27 2014/10/16 rogid:2oqRV2O8vmW9f6FeX+td6cvhyNI9606 rogid:olV8Tqn3hDJjyAbn6x/m5ncNoEA9606 intact-crc:14E614ECCA990DA5|rigid:V/tKZGxxroGxs0RqFHLXMrrW3Lw false - ha tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)