#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P06716	uniprotkb:P17315	intact:EBI-7386310|intact:MINT-4794283	intact:EBI-1124042|uniprotkb:Q2MAS4|ensemblbacteria:AAC75216|ensemblbacteria:BAE76632	psi-mi:ceia_ecolx(display_long)|uniprotkb:cia(gene name)|psi-mi:cia(display_short)	psi-mi:cira_ecoli(display_long)|uniprotkb:cirA(gene name)|psi-mi:cirA(display_short)|uniprotkb:cir(gene name synonym)|uniprotkb:feuA(gene name synonym)|uniprotkb:b2155(locus name)|uniprotkb:JW2142(locus name)	psi-mi:"MI:0114"(x-ray crystallography)	Buchanan et al. (2007)	pubmed:17464289|imex:IM-10828|mint:MINT-5219881	taxid:562(ecolx)|taxid:562(Escherichia coli)	taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7386327|mint:MINT-4794272|imex:IM-10828-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:WP_001582575.1|mint:P06716|interpro:IPR000293(Channel forming colicin, C-terminal cytotoxic)|interpro:IPR014740(Channel forming colicin, central receptor recognition)|interpro:IPR014739(Channel forming colicin, N-terminal translocation)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019835"(cytolysis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|rcsb pdb:1CII|rcsb pdb:2HDI|interpro:IPR038283|mint:MINT-4794274(identity)	refseq:WP_000489247.1|ensemblbacteria:AAC75216(transcript)|ensemblbacteria:b2155(gene)|ensemblbacteria:BAE76632(gene)|ensemblbacteria:BAE76632(transcript)|go:"GO:0009279"(cell outer membrane)|go:"GO:0015343"(siderophore transmembrane transporter activity)|go:"GO:0015344"(siderophore uptake transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031230"(intrinsic component of cell outer membrane)|go:"GO:0042912"(colicin transmembrane transporter activity)|go:"GO:0044718"(siderophore transmembrane transport)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR000531(TonB-dependent receptor, beta-barrel)|interpro:IPR010916(TonB box, conserved site)|interpro:IPR010917(TonB-dependent receptor, conserved site)|interpro:IPR012910(TonB-dependent receptor, plug)|interpro:IPR036942|interpro:IPR037066|interpro:IPR039426|rcsb pdb:2HDF|rcsb pdb:2HDI|refseq:NP_416660.1|mint:P17315|dip:DIP-9282N|mint:MINT-4794273(identity)	-	comment:mint|function:Colicins are polypeptide toxins produced by and active against, Escherichia coli and closely related bacteria|function:This colicin is a channel-forming colicin. This class of transmembrane toxins depolarize the cytoplasmic membrane, leading to dissipation of cellular energy	-	figure legend:F3|figure legend:F2|figure legend:F1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/07/02	2014/10/16	rogid:NemMizk4Ie/FYZq3nJLgU/IiZTE562	rogid:2wI411nNcQr8XFCb6L2WnMFXayI83333	intact-crc:2F5859B58F5ED2B6|rigid:iA+ecLI1ODzdvpFIk6yBefdU0Ew	false	binding-associated region:282-385(MINT-4794288)	binding-associated region:26-663(MINT-4794280)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)