#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O08756 uniprotkb:Q8NBK3 intact:EBI-8354347|intact:MINT-1861176 intact:EBI-2853497|uniprotkb:Q0VAC7|uniprotkb:Q53ZE4|uniprotkb:Q2NL78|uniprotkb:Q96AK5|uniprotkb:Q6UY39|uniprotkb:Q96DK8|uniprotkb:B4DXK5|uniprotkb:E9PGL0|uniprotkb:G5E9B0|uniprotkb:Q0VAC6|uniprotkb:B7XD05|ensembl:ENSP00000272902 psi-mi:hcd2_mouse(display_long)|uniprotkb:Erab(gene name synonym)|uniprotkb:Hsd17b10(gene name)|psi-mi:Hsd17b10(display_short)|uniprotkb:Hadh2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym) psi-mi:sumf1_human(display_long)|uniprotkb:C-alpha-formylglycine-generating enzyme 1(gene name synonym)|uniprotkb:SUMF1(gene name)|psi-mi:SUMF1(display_short)|uniprotkb:UNQ3037/PRO9852(orf name)|uniprotkb:PSEC0152(orf name)|uniprotkb:Sulfatase-modifying factor 1(gene name synonym) psi-mi:"MI:0428"(imaging technique) Zito et al. (2007) pubmed:17446859|imex:IM-11496|mint:MINT-5219864 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7381415|mint:MINT-4793820|imex:IM-11496-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR020904|interpro:IPR036291|mint:O08756|go:"GO:0000049"(tRNA binding)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0018454"(acetoacetyl-CoA reductase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|reactome:R-MMU-70895|interpro:IPR002347(Glucose/ribitol dehydrogenase)|mint:MINT-4793822(identity) refseq:NP_877437.2|refseq:NP_001158146.1|refseq:NP_001158147.1|ensembl:ENSG00000144455(gene)|ensembl:ENST00000272902(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0018158"(protein oxidation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0120147"(Formylglycine-generating oxidase activity)|interpro:IPR005532(Sulphate-modifying factor-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR042095|mint:Q8NBK3|rcsb pdb:1Y1E|rcsb pdb:1Y1F|rcsb pdb:1Y1G|rcsb pdb:1Y1H|rcsb pdb:1Y1I|rcsb pdb:1Y1J|rcsb pdb:1Z70|rcsb pdb:2AFT|rcsb pdb:2AFY|rcsb pdb:2AII|rcsb pdb:2AIJ|rcsb pdb:2AIK|rcsb pdb:2HI8|rcsb pdb:2HIB|reactome:R-HSA-1660662|reactome:R-HSA-1663150|go:"GO:1903135"(cupric ion binding)|mint:MINT-4793821(identity) go:"GO:0005783"(endoplasmic reticulum) comment:mint - figure legend:F2|comment:organelles|comment:The same occurs in Hela cells.|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2007/07/02 2014/10/16 rogid:Txf1MSOnfv3MjmnyRmAf8fDsWew10090 rogid:iVAp2e+KZLp8zO84aeJugruQTM89606 intact-crc:D3EFA3F19369E73A|rigid:+YeL/j69pzyRc0czwHu305yM23s false - flag tag:?-?(MINT-4793831) - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P11438 uniprotkb:Q8NBK3 intact:EBI-987439|uniprotkb:Q62020|ensembl:ENSMUSP00000033824 intact:EBI-2853497|uniprotkb:Q0VAC7|uniprotkb:Q53ZE4|uniprotkb:Q2NL78|uniprotkb:Q96AK5|uniprotkb:Q6UY39|uniprotkb:Q96DK8|uniprotkb:B4DXK5|uniprotkb:E9PGL0|uniprotkb:G5E9B0|uniprotkb:Q0VAC6|uniprotkb:B7XD05|ensembl:ENSP00000272902 psi-mi:lamp1_mouse(display_long)|uniprotkb:Lysosomal membrane glycoprotein A(gene name synonym)|uniprotkb:120 kDa lysosomal membrane glycoprotein(gene name synonym)|uniprotkb:LGP-120(gene name synonym)|uniprotkb:P2B(gene name synonym)|uniprotkb:CD107 antigen-like family member A(gene name synonym)|uniprotkb:Lamp1(gene name)|psi-mi:Lamp1(display_short)|uniprotkb:Lamp-1(gene name synonym) psi-mi:sumf1_human(display_long)|uniprotkb:C-alpha-formylglycine-generating enzyme 1(gene name synonym)|uniprotkb:SUMF1(gene name)|psi-mi:SUMF1(display_short)|uniprotkb:UNQ3037/PRO9852(orf name)|uniprotkb:PSEC0152(orf name)|uniprotkb:Sulfatase-modifying factor 1(gene name synonym) psi-mi:"MI:0428"(imaging technique) Zito et al. (2007) pubmed:17446859|imex:IM-11496|mint:MINT-5219864 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-7381449|mint:MINT-4793837|imex:IM-11496-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031447(gene)|ensembl:ENSMUST00000033824(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|refseq:NP_034814.2|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043323"(positive regulation of natural killer cell degranulation)|go:"GO:0044194"(cytolytic granule)|go:"GO:0044754"(autolysosome)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0061474"(phagolysosome membrane)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0005829"(cytosol)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0101004"(cytolytic granule membrane)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1902513"(regulation of organelle transport along microtubule)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|mint:P11438|rcsb pdb:5GV0|reactome:R-MMU-6798695|refseq:NP_001304282.1|mint:MINT-4793845(identity) refseq:NP_877437.2|refseq:NP_001158146.1|refseq:NP_001158147.1|ensembl:ENSG00000144455(gene)|ensembl:ENST00000272902(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0018158"(protein oxidation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043687"(post-translational protein modification)|go:"GO:0120147"(Formylglycine-generating oxidase activity)|interpro:IPR005532(Sulphate-modifying factor-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR042095|mint:Q8NBK3|rcsb pdb:1Y1E|rcsb pdb:1Y1F|rcsb pdb:1Y1G|rcsb pdb:1Y1H|rcsb pdb:1Y1I|rcsb pdb:1Y1J|rcsb pdb:1Z70|rcsb pdb:2AFT|rcsb pdb:2AFY|rcsb pdb:2AII|rcsb pdb:2AIJ|rcsb pdb:2AIK|rcsb pdb:2HI8|rcsb pdb:2HIB|reactome:R-HSA-1660662|reactome:R-HSA-1663150|go:"GO:1903135"(cupric ion binding)|mint:MINT-4793839(identity) go:"GO:0005768"(endosome) - - figure legend:F2|comment:organelles|comment:The same occurs in Hela cells.|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-embryonic_fibroblast)|taxid:10090(Mus musculus embryonic fibroblasts) - 2007/07/02 2014/10/16 rogid:34kBKJCpWncY9gLqL2lEx3Yn01I10090 rogid:iVAp2e+KZLp8zO84aeJugruQTM89606 intact-crc:967301B5733EEE3F|rigid:KBzsmGhEkvVzCD8X/WHBq4Usf74 false - flag tag:?-?(MINT-4793842) - - psi-mi:"MI:0661"(experimental participant identification) psi-mi:"MI:0661"(experimental participant identification)