#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P42939 uniprotkb:Q99176 intact:EBI-23478|uniprotkb:D6VUY9|ensemblfungi:YGR206W intact:EBI-18076|uniprotkb:Q02806|uniprotkb:D6VYB7|ensemblfungi:YLR119W psi-mi:mvb12_yeast(display_long)|uniprotkb:YGR206W(locus name)|uniprotkb:G7740(orf name)|uniprotkb:12 kDa multivesicular body sorting factor(gene name synonym)|uniprotkb:ESCRT-I complex subunit MVB12(gene name synonym)|uniprotkb:MVB12(gene name)|psi-mi:MVB12(display_short) psi-mi:srn2_yeast(display_long)|uniprotkb:SRN2(gene name)|psi-mi:SRN2(display_short)|uniprotkb:ESCRT-I complex subunit VPS37(gene name synonym)|uniprotkb:SRN10(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 37(gene name synonym)|uniprotkb:VPS37(gene name synonym)|uniprotkb:L2958(orf name)|uniprotkb:L9233.5(orf name)|uniprotkb:YLR119W(locus name) psi-mi:"MI:0114"(x-ray crystallography) Kostelansky et al. (2007) imex:IM-11932|pubmed:17442384 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1267663|wwpdb:2p22|imex:IM-11932-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003438|refseq:NP_011722.3|dip:DIP-5332N|mint:P42939|ensemblfungi:YGR206W(gene)|ensemblfungi:YGR206W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:1904669"(ATP export)|interpro:IPR019014|rcsb pdb:2P22 refseq:NP_013220.1|sgd:S000004109|ensemblfungi:YLR119W(gene)|ensemblfungi:YLR119W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1904669"(ATP export)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR017435(ESCRT-1 complex, Vps37, fungi)|interpro:IPR029012|interpro:IPR037202|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2P22|reactome:R-SCE-917729|dip:DIP-2130N|mint:Q99176 go:"GO:0000813"(ESCRT I complex) crc64:E48B085E0FACBAC8 crc64:4E99806CED03E345 3d-r-factors:working 23.3 percent, free 31.5 percent|3d-resolution:2.70 A|figure legend:2, 3 Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/06/22 2014/10/16 rogid:XlSRoo5SpaD9+m2WkB7l+s9Cs7k559292 rogid:wblVLLKErpKLCkk0FtkAnrWkEFA559292 intact-crc:F4D569AC1F9CA427|rigid:clS5vb4r19haeZy+UvIKiaAkSiM false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42939 uniprotkb:P25604 intact:EBI-23478|uniprotkb:D6VUY9|ensemblfungi:YGR206W intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C psi-mi:mvb12_yeast(display_long)|uniprotkb:YGR206W(locus name)|uniprotkb:G7740(orf name)|uniprotkb:12 kDa multivesicular body sorting factor(gene name synonym)|uniprotkb:ESCRT-I complex subunit MVB12(gene name synonym)|uniprotkb:MVB12(gene name)|psi-mi:MVB12(display_short) psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Kostelansky et al. (2007) imex:IM-11932|pubmed:17442384 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1267663|wwpdb:2p22|imex:IM-11932-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003438|refseq:NP_011722.3|dip:DIP-5332N|mint:P42939|ensemblfungi:YGR206W(gene)|ensemblfungi:YGR206W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:1904669"(ATP export)|interpro:IPR019014|rcsb pdb:2P22 refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N go:"GO:0000813"(ESCRT I complex) crc64:E48B085E0FACBAC8 crc64:FEDE3BE79F063BCE 3d-r-factors:working 23.3 percent, free 31.5 percent|3d-resolution:2.70 A|figure legend:2, 3 Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/06/22 2014/10/16 rogid:XlSRoo5SpaD9+m2WkB7l+s9Cs7k559292 rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292 intact-crc:F4D569AC1F9CA427|rigid:clS5vb4r19haeZy+UvIKiaAkSiM false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42939 uniprotkb:Q02767 intact:EBI-23478|uniprotkb:D6VUY9|ensemblfungi:YGR206W intact:EBI-20387|uniprotkb:P87328|uniprotkb:D6W3V0|uniprotkb:E9P8X2|ensemblfungi:YPL065W psi-mi:mvb12_yeast(display_long)|uniprotkb:YGR206W(locus name)|uniprotkb:G7740(orf name)|uniprotkb:12 kDa multivesicular body sorting factor(gene name synonym)|uniprotkb:ESCRT-I complex subunit MVB12(gene name synonym)|uniprotkb:MVB12(gene name)|psi-mi:MVB12(display_short) psi-mi:vps28_yeast(display_long)|uniprotkb:VPS28(gene name)|psi-mi:VPS28(display_short)|uniprotkb:VPT28(gene name synonym)|uniprotkb:YPL065W(locus name)|uniprotkb:LPE5W(orf name)|uniprotkb:ESCRT-I complex subunit VPS28(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Kostelansky et al. (2007) imex:IM-11932|pubmed:17442384 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1267663|wwpdb:2p22|imex:IM-11932-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003438|refseq:NP_011722.3|dip:DIP-5332N|mint:P42939|ensemblfungi:YGR206W(gene)|ensemblfungi:YGR206W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:1904669"(ATP export)|interpro:IPR019014|rcsb pdb:2P22 refseq:NP_015260.1|sgd:S000005986|ensemblfungi:YPL065W(gene)|ensemblfungi:YPL065W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1904669"(ATP export)|interpro:IPR007143(Vacuolar protein sorting-associated, VPS28)|interpro:IPR017898|interpro:IPR017899|interpro:IPR037202|interpro:IPR037206|interpro:IPR038358|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2G3K|rcsb pdb:2J9U|rcsb pdb:2J9V|rcsb pdb:2P22|reactome:R-SCE-917729|dip:DIP-5828N|mint:Q02767 go:"GO:0000813"(ESCRT I complex) crc64:E48B085E0FACBAC8 crc64:DE091D3F60C9D132 3d-r-factors:working 23.3 percent, free 31.5 percent|3d-resolution:2.70 A|figure legend:2, 3 Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/06/22 2014/10/16 rogid:XlSRoo5SpaD9+m2WkB7l+s9Cs7k559292 rogid:RO7j6SSuuDr3UcxmQoMbXy6ULsA559292 intact-crc:F4D569AC1F9CA427|rigid:clS5vb4r19haeZy+UvIKiaAkSiM false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42939 uniprotkb:P25604 intact:EBI-23478|uniprotkb:D6VUY9|ensemblfungi:YGR206W intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C psi-mi:mvb12_yeast(display_long)|uniprotkb:YGR206W(locus name)|uniprotkb:G7740(orf name)|uniprotkb:12 kDa multivesicular body sorting factor(gene name synonym)|uniprotkb:ESCRT-I complex subunit MVB12(gene name synonym)|uniprotkb:MVB12(gene name)|psi-mi:MVB12(display_short) psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kostelansky et al. (2007) imex:IM-11932|pubmed:17442384 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1267804|imex:IM-11932-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003438|refseq:NP_011722.3|dip:DIP-5332N|mint:P42939|ensemblfungi:YGR206W(gene)|ensemblfungi:YGR206W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:1904669"(ATP export)|interpro:IPR019014|rcsb pdb:2P22 refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N psi-mi:"MI:0469"(intact) crc64:E48B085E0FACBAC8 crc64:FEDE3BE79F063BCE figure legend:1E, 5D, S5D|comment:The stoichiometry was determined as percent of the protein in the cell lysate. The copurification of Mvb12 and Vps23 required Vps37.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/06/22 2014/10/16 rogid:XlSRoo5SpaD9+m2WkB7l+s9Cs7k559292 rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292 intact-crc:9BA1CB5C753A4BEE|rigid:Ye/DpBl77NiNhkVgY8pl1YGQUzM false green fluorescent protein tag:?-?|mutation decreasing interaction:57-57,47-47 ha tag:?-?|mutation decreasing interaction:254-254 1 1 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q99176 uniprotkb:P25604 intact:EBI-18076|uniprotkb:Q02806|uniprotkb:D6VYB7|ensemblfungi:YLR119W intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C psi-mi:srn2_yeast(display_long)|uniprotkb:SRN2(gene name)|psi-mi:SRN2(display_short)|uniprotkb:ESCRT-I complex subunit VPS37(gene name synonym)|uniprotkb:SRN10(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 37(gene name synonym)|uniprotkb:VPS37(gene name synonym)|uniprotkb:L2958(orf name)|uniprotkb:L9233.5(orf name)|uniprotkb:YLR119W(locus name) psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kostelansky et al. (2007) imex:IM-11932|pubmed:17442384 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1268045|imex:IM-11932-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_013220.1|sgd:S000004109|ensemblfungi:YLR119W(gene)|ensemblfungi:YLR119W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1904669"(ATP export)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR017435(ESCRT-1 complex, Vps37, fungi)|interpro:IPR029012|interpro:IPR037202|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2P22|reactome:R-SCE-917729|dip:DIP-2130N|mint:Q99176 refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N psi-mi:"MI:0469"(intact) crc64:4E99806CED03E345 crc64:FEDE3BE79F063BCE figure legend:5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/06/22 2014/10/16 rogid:wblVLLKErpKLCkk0FtkAnrWkEFA559292 rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292 intact-crc:13210FEE477A60E1|rigid:Iky1ZI3xywrX5t1QNEGRghepsNA false myc tag:?-? mutation decreasing interaction:254-254|ha tag:?-? - 1 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P42939 uniprotkb:Q99176 intact:EBI-23478|uniprotkb:D6VUY9|ensemblfungi:YGR206W intact:EBI-18076|uniprotkb:Q02806|uniprotkb:D6VYB7|ensemblfungi:YLR119W psi-mi:mvb12_yeast(display_long)|uniprotkb:YGR206W(locus name)|uniprotkb:G7740(orf name)|uniprotkb:12 kDa multivesicular body sorting factor(gene name synonym)|uniprotkb:ESCRT-I complex subunit MVB12(gene name synonym)|uniprotkb:MVB12(gene name)|psi-mi:MVB12(display_short) psi-mi:srn2_yeast(display_long)|uniprotkb:SRN2(gene name)|psi-mi:SRN2(display_short)|uniprotkb:ESCRT-I complex subunit VPS37(gene name synonym)|uniprotkb:SRN10(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 37(gene name synonym)|uniprotkb:VPS37(gene name synonym)|uniprotkb:L2958(orf name)|uniprotkb:L9233.5(orf name)|uniprotkb:YLR119W(locus name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kostelansky et al. (2007) imex:IM-11932|pubmed:17442384 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1268059|imex:IM-11932-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003438|refseq:NP_011722.3|dip:DIP-5332N|mint:P42939|ensemblfungi:YGR206W(gene)|ensemblfungi:YGR206W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:1904669"(ATP export)|interpro:IPR019014|rcsb pdb:2P22 refseq:NP_013220.1|sgd:S000004109|ensemblfungi:YLR119W(gene)|ensemblfungi:YLR119W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1904669"(ATP export)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR017435(ESCRT-1 complex, Vps37, fungi)|interpro:IPR029012|interpro:IPR037202|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2P22|reactome:R-SCE-917729|dip:DIP-2130N|mint:Q99176 psi-mi:"MI:0469"(intact) crc64:E48B085E0FACBAC8 crc64:4E99806CED03E345 figure legend:5E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/06/22 2014/10/16 rogid:XlSRoo5SpaD9+m2WkB7l+s9Cs7k559292 rogid:wblVLLKErpKLCkk0FtkAnrWkEFA559292 intact-crc:928D2940AB47974B|rigid:iXS256yAKWuRipBBRRzHOq9ewXQ false yellow fluorescent protein tag:?-?|mutation decreasing interaction:57-57,47-47 myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P25604 uniprotkb:P42939 intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C intact:EBI-23478|uniprotkb:D6VUY9|ensemblfungi:YGR206W psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym) psi-mi:mvb12_yeast(display_long)|uniprotkb:YGR206W(locus name)|uniprotkb:G7740(orf name)|uniprotkb:12 kDa multivesicular body sorting factor(gene name synonym)|uniprotkb:ESCRT-I complex subunit MVB12(gene name synonym)|uniprotkb:MVB12(gene name)|psi-mi:MVB12(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Kostelansky et al. (2007) imex:IM-11932|pubmed:17442384 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1268071|imex:IM-11932-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N sgd:S000003438|refseq:NP_011722.3|dip:DIP-5332N|mint:P42939|ensemblfungi:YGR206W(gene)|ensemblfungi:YGR206W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:1904669"(ATP export)|interpro:IPR019014|rcsb pdb:2P22 psi-mi:"MI:0469"(intact) crc64:FEDE3BE79F063BCE crc64:E48B085E0FACBAC8 figure legend:5E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/06/22 2014/10/16 rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292 rogid:XlSRoo5SpaD9+m2WkB7l+s9Cs7k559292 intact-crc:BDBC7491F3E6193A|rigid:Ye/DpBl77NiNhkVgY8pl1YGQUzM false ha tag:?-? yellow fluorescent protein tag:?-?|mutation decreasing interaction:57-57,47-47 1 1 psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P42939 uniprotkb:Q99176 intact:EBI-23478|uniprotkb:D6VUY9|ensemblfungi:YGR206W intact:EBI-18076|uniprotkb:Q02806|uniprotkb:D6VYB7|ensemblfungi:YLR119W psi-mi:mvb12_yeast(display_long)|uniprotkb:YGR206W(locus name)|uniprotkb:G7740(orf name)|uniprotkb:12 kDa multivesicular body sorting factor(gene name synonym)|uniprotkb:ESCRT-I complex subunit MVB12(gene name synonym)|uniprotkb:MVB12(gene name)|psi-mi:MVB12(display_short) psi-mi:srn2_yeast(display_long)|uniprotkb:SRN2(gene name)|psi-mi:SRN2(display_short)|uniprotkb:ESCRT-I complex subunit VPS37(gene name synonym)|uniprotkb:SRN10(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 37(gene name synonym)|uniprotkb:VPS37(gene name synonym)|uniprotkb:L2958(orf name)|uniprotkb:L9233.5(orf name)|uniprotkb:YLR119W(locus name) psi-mi:"MI:0071"(molecular sieving) Kostelansky et al. (2007) imex:IM-11932|pubmed:17442384 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1267964|imex:IM-11932-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003438|refseq:NP_011722.3|dip:DIP-5332N|mint:P42939|ensemblfungi:YGR206W(gene)|ensemblfungi:YGR206W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:1904669"(ATP export)|interpro:IPR019014|rcsb pdb:2P22 refseq:NP_013220.1|sgd:S000004109|ensemblfungi:YLR119W(gene)|ensemblfungi:YLR119W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1904669"(ATP export)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR017435(ESCRT-1 complex, Vps37, fungi)|interpro:IPR029012|interpro:IPR037202|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2P22|reactome:R-SCE-917729|dip:DIP-2130N|mint:Q99176 go:"GO:0000813"(ESCRT I complex) crc64:E48B085E0FACBAC8 crc64:4E99806CED03E345 figure legend:4B|complex-properties:ESCRT-I complex consisting of intact Vps23, Vps28, Vps37, and Mvb12 runs on gel filtration chromatography with an apparent molecular weight of 340 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/06/22 2014/10/16 rogid:XlSRoo5SpaD9+m2WkB7l+s9Cs7k559292 rogid:wblVLLKErpKLCkk0FtkAnrWkEFA559292 intact-crc:CE58F5AA8C92E078|rigid:clS5vb4r19haeZy+UvIKiaAkSiM false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42939 uniprotkb:P25604 intact:EBI-23478|uniprotkb:D6VUY9|ensemblfungi:YGR206W intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C psi-mi:mvb12_yeast(display_long)|uniprotkb:YGR206W(locus name)|uniprotkb:G7740(orf name)|uniprotkb:12 kDa multivesicular body sorting factor(gene name synonym)|uniprotkb:ESCRT-I complex subunit MVB12(gene name synonym)|uniprotkb:MVB12(gene name)|psi-mi:MVB12(display_short) psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Kostelansky et al. (2007) imex:IM-11932|pubmed:17442384 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1267964|imex:IM-11932-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003438|refseq:NP_011722.3|dip:DIP-5332N|mint:P42939|ensemblfungi:YGR206W(gene)|ensemblfungi:YGR206W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:1904669"(ATP export)|interpro:IPR019014|rcsb pdb:2P22 refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N go:"GO:0000813"(ESCRT I complex) crc64:E48B085E0FACBAC8 crc64:FEDE3BE79F063BCE figure legend:4B|complex-properties:ESCRT-I complex consisting of intact Vps23, Vps28, Vps37, and Mvb12 runs on gel filtration chromatography with an apparent molecular weight of 340 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/06/22 2014/10/16 rogid:XlSRoo5SpaD9+m2WkB7l+s9Cs7k559292 rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292 intact-crc:CE58F5AA8C92E078|rigid:clS5vb4r19haeZy+UvIKiaAkSiM false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42939 uniprotkb:Q02767 intact:EBI-23478|uniprotkb:D6VUY9|ensemblfungi:YGR206W intact:EBI-20387|uniprotkb:P87328|uniprotkb:D6W3V0|uniprotkb:E9P8X2|ensemblfungi:YPL065W psi-mi:mvb12_yeast(display_long)|uniprotkb:YGR206W(locus name)|uniprotkb:G7740(orf name)|uniprotkb:12 kDa multivesicular body sorting factor(gene name synonym)|uniprotkb:ESCRT-I complex subunit MVB12(gene name synonym)|uniprotkb:MVB12(gene name)|psi-mi:MVB12(display_short) psi-mi:vps28_yeast(display_long)|uniprotkb:VPS28(gene name)|psi-mi:VPS28(display_short)|uniprotkb:VPT28(gene name synonym)|uniprotkb:YPL065W(locus name)|uniprotkb:LPE5W(orf name)|uniprotkb:ESCRT-I complex subunit VPS28(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Kostelansky et al. (2007) imex:IM-11932|pubmed:17442384 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1267964|imex:IM-11932-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003438|refseq:NP_011722.3|dip:DIP-5332N|mint:P42939|ensemblfungi:YGR206W(gene)|ensemblfungi:YGR206W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:1904669"(ATP export)|interpro:IPR019014|rcsb pdb:2P22 refseq:NP_015260.1|sgd:S000005986|ensemblfungi:YPL065W(gene)|ensemblfungi:YPL065W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1904669"(ATP export)|interpro:IPR007143(Vacuolar protein sorting-associated, VPS28)|interpro:IPR017898|interpro:IPR017899|interpro:IPR037202|interpro:IPR037206|interpro:IPR038358|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2G3K|rcsb pdb:2J9U|rcsb pdb:2J9V|rcsb pdb:2P22|reactome:R-SCE-917729|dip:DIP-5828N|mint:Q02767 go:"GO:0000813"(ESCRT I complex) crc64:E48B085E0FACBAC8 crc64:DE091D3F60C9D132 figure legend:4B|complex-properties:ESCRT-I complex consisting of intact Vps23, Vps28, Vps37, and Mvb12 runs on gel filtration chromatography with an apparent molecular weight of 340 kDa|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/06/22 2014/10/16 rogid:XlSRoo5SpaD9+m2WkB7l+s9Cs7k559292 rogid:RO7j6SSuuDr3UcxmQoMbXy6ULsA559292 intact-crc:CE58F5AA8C92E078|rigid:clS5vb4r19haeZy+UvIKiaAkSiM false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42939 uniprotkb:Q99176 intact:EBI-23478|uniprotkb:D6VUY9|ensemblfungi:YGR206W intact:EBI-18076|uniprotkb:Q02806|uniprotkb:D6VYB7|ensemblfungi:YLR119W psi-mi:mvb12_yeast(display_long)|uniprotkb:YGR206W(locus name)|uniprotkb:G7740(orf name)|uniprotkb:12 kDa multivesicular body sorting factor(gene name synonym)|uniprotkb:ESCRT-I complex subunit MVB12(gene name synonym)|uniprotkb:MVB12(gene name)|psi-mi:MVB12(display_short) psi-mi:srn2_yeast(display_long)|uniprotkb:SRN2(gene name)|psi-mi:SRN2(display_short)|uniprotkb:ESCRT-I complex subunit VPS37(gene name synonym)|uniprotkb:SRN10(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 37(gene name synonym)|uniprotkb:VPS37(gene name synonym)|uniprotkb:L2958(orf name)|uniprotkb:L9233.5(orf name)|uniprotkb:YLR119W(locus name) psi-mi:"MI:0028"(cosedimentation in solution) Kostelansky et al. (2007) imex:IM-11932|pubmed:17442384 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1267979|imex:IM-11932-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003438|refseq:NP_011722.3|dip:DIP-5332N|mint:P42939|ensemblfungi:YGR206W(gene)|ensemblfungi:YGR206W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:1904669"(ATP export)|interpro:IPR019014|rcsb pdb:2P22 refseq:NP_013220.1|sgd:S000004109|ensemblfungi:YLR119W(gene)|ensemblfungi:YLR119W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1904669"(ATP export)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR009851(Modifier of rudimentary, Modr)|interpro:IPR017435(ESCRT-1 complex, Vps37, fungi)|interpro:IPR029012|interpro:IPR037202|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2P22|reactome:R-SCE-917729|dip:DIP-2130N|mint:Q99176 go:"GO:0000813"(ESCRT I complex) crc64:E48B085E0FACBAC8 crc64:4E99806CED03E345 figure legend:4B|complex-properties:ESCRT-I complex has a molecular mass of 117 Kda.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/06/22 2014/10/16 rogid:XlSRoo5SpaD9+m2WkB7l+s9Cs7k559292 rogid:wblVLLKErpKLCkk0FtkAnrWkEFA559292 intact-crc:7872FA1ADE05F1B7|rigid:clS5vb4r19haeZy+UvIKiaAkSiM false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42939 uniprotkb:P25604 intact:EBI-23478|uniprotkb:D6VUY9|ensemblfungi:YGR206W intact:EBI-411625|uniprotkb:D6VR04|uniprotkb:P87010|uniprotkb:P87279|uniprotkb:Q86ZT3|uniprotkb:Q8NIM6|ensemblfungi:YCL008C psi-mi:mvb12_yeast(display_long)|uniprotkb:YGR206W(locus name)|uniprotkb:G7740(orf name)|uniprotkb:12 kDa multivesicular body sorting factor(gene name synonym)|uniprotkb:ESCRT-I complex subunit MVB12(gene name synonym)|uniprotkb:MVB12(gene name)|psi-mi:MVB12(display_short) psi-mi:stp22_yeast(display_long)|uniprotkb:STP22(gene name)|psi-mi:STP22(display_short)|uniprotkb:VPS23(gene name synonym)|uniprotkb:YCL008C(locus name)|uniprotkb:YCL8C(orf name)|uniprotkb:Vacuolar protein sorting-associated protein 23(gene name synonym)|uniprotkb:ESCRT-I complex subunit VPS23(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Kostelansky et al. (2007) imex:IM-11932|pubmed:17442384 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1267979|imex:IM-11932-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003438|refseq:NP_011722.3|dip:DIP-5332N|mint:P42939|ensemblfungi:YGR206W(gene)|ensemblfungi:YGR206W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:1904669"(ATP export)|interpro:IPR019014|rcsb pdb:2P22 refseq:NP_009919.3|sgd:S000000514|ensemblfungi:YCL008C(gene)|ensemblfungi:YCL008C_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0061709"(reticulophagy)|go:"GO:1902915"(negative regulation of protein polyubiquitination)|go:"GO:1904669"(ATP export)|interpro:IPR008883(Tumour susceptibility gene 101)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR017916|interpro:IPR037202|rcsb pdb:1UZX|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2P22|rcsb pdb:3R3Q|rcsb pdb:3R42|reactome:R-SCE-917729|mint:P25604|dip:DIP-5827N go:"GO:0000813"(ESCRT I complex) crc64:E48B085E0FACBAC8 crc64:FEDE3BE79F063BCE figure legend:4B|complex-properties:ESCRT-I complex has a molecular mass of 117 Kda.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/06/22 2014/10/16 rogid:XlSRoo5SpaD9+m2WkB7l+s9Cs7k559292 rogid:8AIy7kppMJG1UCBtqED5LaKVnmk559292 intact-crc:7872FA1ADE05F1B7|rigid:clS5vb4r19haeZy+UvIKiaAkSiM false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P42939 uniprotkb:Q02767 intact:EBI-23478|uniprotkb:D6VUY9|ensemblfungi:YGR206W intact:EBI-20387|uniprotkb:P87328|uniprotkb:D6W3V0|uniprotkb:E9P8X2|ensemblfungi:YPL065W psi-mi:mvb12_yeast(display_long)|uniprotkb:YGR206W(locus name)|uniprotkb:G7740(orf name)|uniprotkb:12 kDa multivesicular body sorting factor(gene name synonym)|uniprotkb:ESCRT-I complex subunit MVB12(gene name synonym)|uniprotkb:MVB12(gene name)|psi-mi:MVB12(display_short) psi-mi:vps28_yeast(display_long)|uniprotkb:VPS28(gene name)|psi-mi:VPS28(display_short)|uniprotkb:VPT28(gene name synonym)|uniprotkb:YPL065W(locus name)|uniprotkb:LPE5W(orf name)|uniprotkb:ESCRT-I complex subunit VPS28(gene name synonym) psi-mi:"MI:0028"(cosedimentation in solution) Kostelansky et al. (2007) imex:IM-11932|pubmed:17442384 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1267979|imex:IM-11932-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000003438|refseq:NP_011722.3|dip:DIP-5332N|mint:P42939|ensemblfungi:YGR206W(gene)|ensemblfungi:YGR206W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:1904669"(ATP export)|interpro:IPR019014|rcsb pdb:2P22 refseq:NP_015260.1|sgd:S000005986|ensemblfungi:YPL065W(gene)|ensemblfungi:YPL065W_mRNA(transcript)|go:"GO:0000813"(ESCRT I complex)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006623"(protein targeting to vacuole)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1904669"(ATP export)|interpro:IPR007143(Vacuolar protein sorting-associated, VPS28)|interpro:IPR017898|interpro:IPR017899|interpro:IPR037202|interpro:IPR037206|interpro:IPR038358|rcsb pdb:2CAZ|rcsb pdb:2F66|rcsb pdb:2F6M|rcsb pdb:2G3K|rcsb pdb:2J9U|rcsb pdb:2J9V|rcsb pdb:2P22|reactome:R-SCE-917729|dip:DIP-5828N|mint:Q02767 go:"GO:0000813"(ESCRT I complex) crc64:E48B085E0FACBAC8 crc64:DE091D3F60C9D132 figure legend:4B|complex-properties:ESCRT-I complex has a molecular mass of 117 Kda.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/06/22 2014/10/16 rogid:XlSRoo5SpaD9+m2WkB7l+s9Cs7k559292 rogid:RO7j6SSuuDr3UcxmQoMbXy6ULsA559292 intact-crc:7872FA1ADE05F1B7|rigid:clS5vb4r19haeZy+UvIKiaAkSiM false - - 1 1 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)