#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q01196	uniprotkb:Q00534	intact:EBI-925904|uniprotkb:O60472|uniprotkb:O60473|uniprotkb:O76047|uniprotkb:O76089|uniprotkb:Q13081|uniprotkb:Q13755|uniprotkb:Q13756|uniprotkb:Q13757|uniprotkb:Q13758|uniprotkb:Q13759|uniprotkb:Q15341|uniprotkb:Q15343|uniprotkb:Q16122|uniprotkb:Q16284|uniprotkb:Q16285|uniprotkb:Q16286|uniprotkb:Q16346|uniprotkb:Q16347|uniprotkb:Q92479|uniprotkb:A8MV94|uniprotkb:B2RMS4|uniprotkb:D3DSG1|ensembl:ENSP00000340690	intact:EBI-295663|uniprotkb:A4D1G0|ensembl:ENSP00000265734|ensembl:ENSP00000397087	psi-mi:runx1_human(display_long)|uniprotkb:RUNX1(gene name)|psi-mi:RUNX1(display_short)|uniprotkb:AML1(gene name synonym)|uniprotkb:CBFA2(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym)	psi-mi:cdk6_human(display_long)|uniprotkb:CDK6(gene name)|psi-mi:CDK6(display_short)|uniprotkb:Serine/threonine-protein kinase PLSTIRE(gene name synonym)|uniprotkb:Cell division protein kinase 6(gene name synonym)|uniprotkb:CDKN6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fujimoto et al. (2007)	pubmed:17431401|imex:IM-10926|mint:MINT-5219852	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7375674|mint:MINT-4791064|imex:IM-10926-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011528068.1|refseq:NP_001001890.1|refseq:NP_001116079.1|refseq:NP_001745.2|refseq:XP_005261125.1|dip:DIP-36773N|ensembl:ENSG00000159216(gene)|ensembl:ENST00000344691(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010755"(regulation of plasminogen activation)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903055"(positive regulation of extracellular matrix organization)|go:"GO:1905203"(regulation of connective tissue replacement)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR016554(Transcription factor, Runt-related, RUNX)|interpro:IPR027384|mint:Q01196|rcsb pdb:1CMO|rcsb pdb:1CO1|rcsb pdb:1E50|rcsb pdb:1H9D|rcsb pdb:1LJM|reactome:R-HSA-1912408|reactome:R-HSA-549127|reactome:R-HSA-8877330|reactome:R-HSA-8931987|reactome:R-HSA-8934593|reactome:R-HSA-8935964|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-8939242|reactome:R-HSA-8939243|reactome:R-HSA-8939245|reactome:R-HSA-8939246|reactome:R-HSA-8939247|reactome:R-HSA-8939256|reactome:R-HSA-8941333|reactome:R-HSA-8951936|reactome:R-HSA-9018519|reactome:R-HSA-9616222|mint:MINT-4791066(identity)	refseq:NP_001138778.1|refseq:NP_001250.1|refseq:XP_006715898.1|dip:DIP-687N|ensembl:ENSG00000105810(gene)|ensembl:ENST00000265734(transcript)|ensembl:ENST00000424848(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001726"(ruffle)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009615"(response to virus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014002"(astrocyte development)|go:"GO:0016592"(mediator complex)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030332"(cyclin binding)|go:"GO:0042063"(gliogenesis)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048699"(generation of neurons)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028788|mint:Q00534|rcsb pdb:1BI7|rcsb pdb:1BI8|rcsb pdb:1BLX|rcsb pdb:1G3N|rcsb pdb:1JOW|rcsb pdb:1XO2|rcsb pdb:2EUF|rcsb pdb:2F2C|rcsb pdb:3NUP|rcsb pdb:3NUX|rcsb pdb:4AUA|rcsb pdb:4EZ5|rcsb pdb:4TTH|rcsb pdb:5L2I|rcsb pdb:5L2S|rcsb pdb:5L2T|rcsb pdb:6OQL|rcsb pdb:6OQO|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-69231|reactome:R-HSA-8934593|reactome:R-HSA-9630794|reactome:R-HSA-9632700|reactome:R-HSA-9661069|mint:MINT-4791065(identity)	-	-	-	figure legend:F3A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/06/05	2014/10/16	rogid:8RknoK1Z7L/Ck94Nd1b9/k03C8k9606	rogid:IlAJCZ9bvB5RaBdS1rlPnqDL9xg9606	intact-crc:EF8C325C69E7BEDD|rigid:Q3awvhNLeJhrgkhWLmoXxOMU3ts	false	flag tag:?-?(MINT-4791070)	ha tag:?-?(MINT-4791075)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q13951	uniprotkb:Q01196	intact:EBI-718750|uniprotkb:Q13124|uniprotkb:Q9HCT2|uniprotkb:A8K347|ensembl:ENSP00000290858	intact:EBI-925904|uniprotkb:O60472|uniprotkb:O60473|uniprotkb:O76047|uniprotkb:O76089|uniprotkb:Q13081|uniprotkb:Q13755|uniprotkb:Q13756|uniprotkb:Q13757|uniprotkb:Q13758|uniprotkb:Q13759|uniprotkb:Q15341|uniprotkb:Q15343|uniprotkb:Q16122|uniprotkb:Q16284|uniprotkb:Q16285|uniprotkb:Q16286|uniprotkb:Q16346|uniprotkb:Q16347|uniprotkb:Q92479|uniprotkb:A8MV94|uniprotkb:B2RMS4|uniprotkb:D3DSG1|ensembl:ENSP00000340690	psi-mi:pebb_human(display_long)|uniprotkb:Polyomavirus enhancer-binding protein 2 beta subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 subunit beta(gene name synonym)|uniprotkb:SL3/AKV core-binding factor beta subunit(gene name synonym)|uniprotkb:CBFB(gene name)|psi-mi:CBFB(display_short)	psi-mi:runx1_human(display_long)|uniprotkb:RUNX1(gene name)|psi-mi:RUNX1(display_short)|uniprotkb:AML1(gene name synonym)|uniprotkb:CBFA2(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fujimoto et al. (2007)	pubmed:17431401|imex:IM-10926|mint:MINT-5219852	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7375788|mint:MINT-4791117|imex:IM-10926-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001746.1|refseq:NP_074036.1|dip:DIP-36772N|ensembl:ENSG00000067955(gene)|ensembl:ENST00000290858(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0060216"(definitive hemopoiesis)|interpro:IPR003417(Core binding factor, beta subunit)|interpro:IPR036552|mint:Q13951|rcsb pdb:1CL3|rcsb pdb:1E50|rcsb pdb:1H9D|rcsb pdb:4N9F|rcsb pdb:6NIL|rcsb pdb:6P59|rcsb pdb:6VGD|rcsb pdb:6VGE|rcsb pdb:6VGG|reactome:R-HSA-8877330|reactome:R-HSA-8878166|reactome:R-HSA-8931987|reactome:R-HSA-8934593|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0030099"(myeloid cell differentiation)|reactome:R-HSA-8935964|reactome:R-HSA-8936459|reactome:R-HSA-8941332|reactome:R-HSA-8941333|reactome:R-HSA-8941858|reactome:R-HSA-8949275|reactome:R-HSA-8951911|reactome:R-HSA-8951936|reactome:R-HSA-9018519|reactome:R-HSA-9616222|reactome:R-HSA-8939236|reactome:R-HSA-8939242|reactome:R-HSA-8939243|reactome:R-HSA-8939245|reactome:R-HSA-8939246|reactome:R-HSA-8939247|reactome:R-HSA-8939256|reactome:R-HSA-8939902|reactome:R-HSA-8940973|reactome:R-HSA-8941284|reactome:R-HSA-8941326|mint:MINT-4791118(identity)	refseq:XP_011528068.1|refseq:NP_001001890.1|refseq:NP_001116079.1|refseq:NP_001745.2|refseq:XP_005261125.1|dip:DIP-36773N|ensembl:ENSG00000159216(gene)|ensembl:ENST00000344691(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010755"(regulation of plasminogen activation)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903055"(positive regulation of extracellular matrix organization)|go:"GO:1905203"(regulation of connective tissue replacement)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR016554(Transcription factor, Runt-related, RUNX)|interpro:IPR027384|mint:Q01196|rcsb pdb:1CMO|rcsb pdb:1CO1|rcsb pdb:1E50|rcsb pdb:1H9D|rcsb pdb:1LJM|reactome:R-HSA-1912408|reactome:R-HSA-549127|reactome:R-HSA-8877330|reactome:R-HSA-8931987|reactome:R-HSA-8934593|reactome:R-HSA-8935964|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-8939242|reactome:R-HSA-8939243|reactome:R-HSA-8939245|reactome:R-HSA-8939246|reactome:R-HSA-8939247|reactome:R-HSA-8939256|reactome:R-HSA-8941333|reactome:R-HSA-8951936|reactome:R-HSA-9018519|reactome:R-HSA-9616222|mint:MINT-4791121(identity)	-	-	-	figure legend:F4A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/06/05	2014/10/16	rogid:CPjRPRBOYrP/Oj+k66XpWQysihY9606	rogid:8RknoK1Z7L/Ck94Nd1b9/k03C8k9606	intact-crc:17BF00CEF0E1CD81|rigid:13ZE6UK+6KjJHAuIMo5Yi9C+2Mk	false	-	flag tag:?-?(MINT-4791122)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01196	uniprotkb:Q00534	intact:EBI-925904|uniprotkb:O60472|uniprotkb:O60473|uniprotkb:O76047|uniprotkb:O76089|uniprotkb:Q13081|uniprotkb:Q13755|uniprotkb:Q13756|uniprotkb:Q13757|uniprotkb:Q13758|uniprotkb:Q13759|uniprotkb:Q15341|uniprotkb:Q15343|uniprotkb:Q16122|uniprotkb:Q16284|uniprotkb:Q16285|uniprotkb:Q16286|uniprotkb:Q16346|uniprotkb:Q16347|uniprotkb:Q92479|uniprotkb:A8MV94|uniprotkb:B2RMS4|uniprotkb:D3DSG1|ensembl:ENSP00000340690	intact:EBI-295663|uniprotkb:A4D1G0|ensembl:ENSP00000265734|ensembl:ENSP00000397087	psi-mi:runx1_human(display_long)|uniprotkb:RUNX1(gene name)|psi-mi:RUNX1(display_short)|uniprotkb:AML1(gene name synonym)|uniprotkb:CBFA2(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym)	psi-mi:cdk6_human(display_long)|uniprotkb:CDK6(gene name)|psi-mi:CDK6(display_short)|uniprotkb:Serine/threonine-protein kinase PLSTIRE(gene name synonym)|uniprotkb:Cell division protein kinase 6(gene name synonym)|uniprotkb:CDKN6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fujimoto et al. (2007)	pubmed:17431401|imex:IM-10926|mint:MINT-5219852	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7375746|mint:MINT-4791100|imex:IM-10926-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011528068.1|refseq:NP_001001890.1|refseq:NP_001116079.1|refseq:NP_001745.2|refseq:XP_005261125.1|dip:DIP-36773N|ensembl:ENSG00000159216(gene)|ensembl:ENST00000344691(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010755"(regulation of plasminogen activation)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903055"(positive regulation of extracellular matrix organization)|go:"GO:1905203"(regulation of connective tissue replacement)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR016554(Transcription factor, Runt-related, RUNX)|interpro:IPR027384|mint:Q01196|rcsb pdb:1CMO|rcsb pdb:1CO1|rcsb pdb:1E50|rcsb pdb:1H9D|rcsb pdb:1LJM|reactome:R-HSA-1912408|reactome:R-HSA-549127|reactome:R-HSA-8877330|reactome:R-HSA-8931987|reactome:R-HSA-8934593|reactome:R-HSA-8935964|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-8939242|reactome:R-HSA-8939243|reactome:R-HSA-8939245|reactome:R-HSA-8939246|reactome:R-HSA-8939247|reactome:R-HSA-8939256|reactome:R-HSA-8941333|reactome:R-HSA-8951936|reactome:R-HSA-9018519|reactome:R-HSA-9616222|mint:MINT-4791106(identity)	refseq:NP_001138778.1|refseq:NP_001250.1|refseq:XP_006715898.1|dip:DIP-687N|ensembl:ENSG00000105810(gene)|ensembl:ENST00000265734(transcript)|ensembl:ENST00000424848(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001726"(ruffle)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009615"(response to virus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014002"(astrocyte development)|go:"GO:0016592"(mediator complex)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030332"(cyclin binding)|go:"GO:0042063"(gliogenesis)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048699"(generation of neurons)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028788|mint:Q00534|rcsb pdb:1BI7|rcsb pdb:1BI8|rcsb pdb:1BLX|rcsb pdb:1G3N|rcsb pdb:1JOW|rcsb pdb:1XO2|rcsb pdb:2EUF|rcsb pdb:2F2C|rcsb pdb:3NUP|rcsb pdb:3NUX|rcsb pdb:4AUA|rcsb pdb:4EZ5|rcsb pdb:4TTH|rcsb pdb:5L2I|rcsb pdb:5L2S|rcsb pdb:5L2T|rcsb pdb:6OQL|rcsb pdb:6OQO|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-69231|reactome:R-HSA-8934593|reactome:R-HSA-9630794|reactome:R-HSA-9632700|reactome:R-HSA-9661069|mint:MINT-4791101(identity)	-	-	-	figure legend:F3D|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/06/05	2014/10/16	rogid:8RknoK1Z7L/Ck94Nd1b9/k03C8k9606	rogid:IlAJCZ9bvB5RaBdS1rlPnqDL9xg9606	intact-crc:15ABFE5AD6C21FE8|rigid:Q3awvhNLeJhrgkhWLmoXxOMU3ts	false	flag tag:?-?(MINT-4791109)	-	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q01196	uniprotkb:Q00534	intact:EBI-925904|uniprotkb:O60472|uniprotkb:O60473|uniprotkb:O76047|uniprotkb:O76089|uniprotkb:Q13081|uniprotkb:Q13755|uniprotkb:Q13756|uniprotkb:Q13757|uniprotkb:Q13758|uniprotkb:Q13759|uniprotkb:Q15341|uniprotkb:Q15343|uniprotkb:Q16122|uniprotkb:Q16284|uniprotkb:Q16285|uniprotkb:Q16286|uniprotkb:Q16346|uniprotkb:Q16347|uniprotkb:Q92479|uniprotkb:A8MV94|uniprotkb:B2RMS4|uniprotkb:D3DSG1|ensembl:ENSP00000340690	intact:EBI-295663|uniprotkb:A4D1G0|ensembl:ENSP00000265734|ensembl:ENSP00000397087	psi-mi:runx1_human(display_long)|uniprotkb:RUNX1(gene name)|psi-mi:RUNX1(display_short)|uniprotkb:AML1(gene name synonym)|uniprotkb:CBFA2(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym)	psi-mi:cdk6_human(display_long)|uniprotkb:CDK6(gene name)|psi-mi:CDK6(display_short)|uniprotkb:Serine/threonine-protein kinase PLSTIRE(gene name synonym)|uniprotkb:Cell division protein kinase 6(gene name synonym)|uniprotkb:CDKN6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fujimoto et al. (2007)	pubmed:17431401|imex:IM-10926|mint:MINT-5219852	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7375858|mint:MINT-4791148|imex:IM-10926-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011528068.1|refseq:NP_001001890.1|refseq:NP_001116079.1|refseq:NP_001745.2|refseq:XP_005261125.1|dip:DIP-36773N|ensembl:ENSG00000159216(gene)|ensembl:ENST00000344691(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010755"(regulation of plasminogen activation)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903055"(positive regulation of extracellular matrix organization)|go:"GO:1905203"(regulation of connective tissue replacement)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR016554(Transcription factor, Runt-related, RUNX)|interpro:IPR027384|mint:Q01196|rcsb pdb:1CMO|rcsb pdb:1CO1|rcsb pdb:1E50|rcsb pdb:1H9D|rcsb pdb:1LJM|reactome:R-HSA-1912408|reactome:R-HSA-549127|reactome:R-HSA-8877330|reactome:R-HSA-8931987|reactome:R-HSA-8934593|reactome:R-HSA-8935964|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-8939242|reactome:R-HSA-8939243|reactome:R-HSA-8939245|reactome:R-HSA-8939246|reactome:R-HSA-8939247|reactome:R-HSA-8939256|reactome:R-HSA-8941333|reactome:R-HSA-8951936|reactome:R-HSA-9018519|reactome:R-HSA-9616222|mint:MINT-4791153(identity)	refseq:NP_001138778.1|refseq:NP_001250.1|refseq:XP_006715898.1|dip:DIP-687N|ensembl:ENSG00000105810(gene)|ensembl:ENST00000265734(transcript)|ensembl:ENST00000424848(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001726"(ruffle)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009615"(response to virus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014002"(astrocyte development)|go:"GO:0016592"(mediator complex)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030332"(cyclin binding)|go:"GO:0042063"(gliogenesis)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048699"(generation of neurons)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028788|mint:Q00534|rcsb pdb:1BI7|rcsb pdb:1BI8|rcsb pdb:1BLX|rcsb pdb:1G3N|rcsb pdb:1JOW|rcsb pdb:1XO2|rcsb pdb:2EUF|rcsb pdb:2F2C|rcsb pdb:3NUP|rcsb pdb:3NUX|rcsb pdb:4AUA|rcsb pdb:4EZ5|rcsb pdb:4TTH|rcsb pdb:5L2I|rcsb pdb:5L2S|rcsb pdb:5L2T|rcsb pdb:6OQL|rcsb pdb:6OQO|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-69231|reactome:R-HSA-8934593|reactome:R-HSA-9630794|reactome:R-HSA-9632700|reactome:R-HSA-9661069|mint:MINT-4791149(identity)	-	-	-	figure legend:F5B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/06/05	2014/10/16	rogid:8RknoK1Z7L/Ck94Nd1b9/k03C8k9606	rogid:IlAJCZ9bvB5RaBdS1rlPnqDL9xg9606	intact-crc:C504E54BDD259BEF|rigid:Q3awvhNLeJhrgkhWLmoXxOMU3ts	false	flag tag:?-?(MINT-4791154)	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0113"(western blot)
uniprotkb:P49715	uniprotkb:Q01196	intact:EBI-1172054|uniprotkb:A7LNP2|uniprotkb:Q05CA4|uniprotkb:P78319|ensembl:ENSP00000427514	intact:EBI-925904|uniprotkb:O60472|uniprotkb:O60473|uniprotkb:O76047|uniprotkb:O76089|uniprotkb:Q13081|uniprotkb:Q13755|uniprotkb:Q13756|uniprotkb:Q13757|uniprotkb:Q13758|uniprotkb:Q13759|uniprotkb:Q15341|uniprotkb:Q15343|uniprotkb:Q16122|uniprotkb:Q16284|uniprotkb:Q16285|uniprotkb:Q16286|uniprotkb:Q16346|uniprotkb:Q16347|uniprotkb:Q92479|uniprotkb:A8MV94|uniprotkb:B2RMS4|uniprotkb:D3DSG1|ensembl:ENSP00000340690	psi-mi:cebpa_human(display_long)|uniprotkb:CEBPA(gene name)|psi-mi:CEBPA(display_short)|uniprotkb:CEBP(gene name synonym)	psi-mi:runx1_human(display_long)|uniprotkb:RUNX1(gene name)|psi-mi:RUNX1(display_short)|uniprotkb:AML1(gene name synonym)|uniprotkb:CBFA2(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fujimoto et al. (2007)	pubmed:17431401|imex:IM-10926|mint:MINT-5219852	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7375803|mint:MINT-4791133|imex:IM-10926-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000245848(gene)|ensembl:ENST00000498907(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019900"(kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048469"(cell maturation)|go:"GO:0048839"(inner ear development)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:P49715|rcsb pdb:6DC0|reactome:R-HSA-381340|reactome:R-HSA-9616222|refseq:NP_004355.2|refseq:NP_001272758.1|refseq:NP_001274353.1|refseq:NP_001274364.1|dip:DIP-37882N|mint:MINT-4791139(identity)	refseq:XP_011528068.1|refseq:NP_001001890.1|refseq:NP_001116079.1|refseq:NP_001745.2|refseq:XP_005261125.1|dip:DIP-36773N|ensembl:ENSG00000159216(gene)|ensembl:ENST00000344691(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010755"(regulation of plasminogen activation)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903055"(positive regulation of extracellular matrix organization)|go:"GO:1905203"(regulation of connective tissue replacement)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR016554(Transcription factor, Runt-related, RUNX)|interpro:IPR027384|mint:Q01196|rcsb pdb:1CMO|rcsb pdb:1CO1|rcsb pdb:1E50|rcsb pdb:1H9D|rcsb pdb:1LJM|reactome:R-HSA-1912408|reactome:R-HSA-549127|reactome:R-HSA-8877330|reactome:R-HSA-8931987|reactome:R-HSA-8934593|reactome:R-HSA-8935964|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-8939242|reactome:R-HSA-8939243|reactome:R-HSA-8939245|reactome:R-HSA-8939246|reactome:R-HSA-8939247|reactome:R-HSA-8939256|reactome:R-HSA-8941333|reactome:R-HSA-8951936|reactome:R-HSA-9018519|reactome:R-HSA-9616222|mint:MINT-4791134(identity)	-	-	-	figure legend:F5B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/06/05	2014/10/16	rogid:uo2VMV1hbdAvsRxr6yU2EVW11nY9606	rogid:8RknoK1Z7L/Ck94Nd1b9/k03C8k9606	intact-crc:EEF438AF61BBC982|rigid:6794C8oGw8eLw+1CPSNmUV6+bcA	false	-	flag tag:?-?(MINT-4791137)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q01196	uniprotkb:Q00534	intact:EBI-925904|uniprotkb:O60472|uniprotkb:O60473|uniprotkb:O76047|uniprotkb:O76089|uniprotkb:Q13081|uniprotkb:Q13755|uniprotkb:Q13756|uniprotkb:Q13757|uniprotkb:Q13758|uniprotkb:Q13759|uniprotkb:Q15341|uniprotkb:Q15343|uniprotkb:Q16122|uniprotkb:Q16284|uniprotkb:Q16285|uniprotkb:Q16286|uniprotkb:Q16346|uniprotkb:Q16347|uniprotkb:Q92479|uniprotkb:A8MV94|uniprotkb:B2RMS4|uniprotkb:D3DSG1|ensembl:ENSP00000340690	intact:EBI-295663|uniprotkb:A4D1G0|ensembl:ENSP00000265734|ensembl:ENSP00000397087	psi-mi:runx1_human(display_long)|uniprotkb:RUNX1(gene name)|psi-mi:RUNX1(display_short)|uniprotkb:AML1(gene name synonym)|uniprotkb:CBFA2(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym)	psi-mi:cdk6_human(display_long)|uniprotkb:CDK6(gene name)|psi-mi:CDK6(display_short)|uniprotkb:Serine/threonine-protein kinase PLSTIRE(gene name synonym)|uniprotkb:Cell division protein kinase 6(gene name synonym)|uniprotkb:CDKN6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Fujimoto et al. (2007)	pubmed:17431401|imex:IM-10926|mint:MINT-5219852	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7375946|mint:MINT-4791080|imex:IM-10926-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011528068.1|refseq:NP_001001890.1|refseq:NP_001116079.1|refseq:NP_001745.2|refseq:XP_005261125.1|dip:DIP-36773N|ensembl:ENSG00000159216(gene)|ensembl:ENST00000344691(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010755"(regulation of plasminogen activation)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903055"(positive regulation of extracellular matrix organization)|go:"GO:1905203"(regulation of connective tissue replacement)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR016554(Transcription factor, Runt-related, RUNX)|interpro:IPR027384|mint:Q01196|rcsb pdb:1CMO|rcsb pdb:1CO1|rcsb pdb:1E50|rcsb pdb:1H9D|rcsb pdb:1LJM|reactome:R-HSA-1912408|reactome:R-HSA-549127|reactome:R-HSA-8877330|reactome:R-HSA-8931987|reactome:R-HSA-8934593|reactome:R-HSA-8935964|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-8939242|reactome:R-HSA-8939243|reactome:R-HSA-8939245|reactome:R-HSA-8939246|reactome:R-HSA-8939247|reactome:R-HSA-8939256|reactome:R-HSA-8941333|reactome:R-HSA-8951936|reactome:R-HSA-9018519|reactome:R-HSA-9616222|mint:MINT-4791086(identity)	refseq:NP_001138778.1|refseq:NP_001250.1|refseq:XP_006715898.1|dip:DIP-687N|ensembl:ENSG00000105810(gene)|ensembl:ENST00000265734(transcript)|ensembl:ENST00000424848(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001726"(ruffle)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003323"(type B pancreatic cell development)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009615"(response to virus)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014002"(astrocyte development)|go:"GO:0016592"(mediator complex)|go:"GO:0021542"(dentate gyrus development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030332"(cyclin binding)|go:"GO:0042063"(gliogenesis)|go:"GO:0043697"(cell dedifferentiation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048699"(generation of neurons)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0098770"(FBXO family protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028788|mint:Q00534|rcsb pdb:1BI7|rcsb pdb:1BI8|rcsb pdb:1BLX|rcsb pdb:1G3N|rcsb pdb:1JOW|rcsb pdb:1XO2|rcsb pdb:2EUF|rcsb pdb:2F2C|rcsb pdb:3NUP|rcsb pdb:3NUX|rcsb pdb:4AUA|rcsb pdb:4EZ5|rcsb pdb:4TTH|rcsb pdb:5L2I|rcsb pdb:5L2S|rcsb pdb:5L2T|rcsb pdb:6OQL|rcsb pdb:6OQO|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-69231|reactome:R-HSA-8934593|reactome:R-HSA-9630794|reactome:R-HSA-9632700|reactome:R-HSA-9661069|mint:MINT-4791081(identity)	-	-	-	figure legend:F3B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-k_562)|taxid:9606(Homo sapiens myeloid leukemia cells.)	-	2007/06/05	2014/10/16	rogid:8RknoK1Z7L/Ck94Nd1b9/k03C8k9606	rogid:IlAJCZ9bvB5RaBdS1rlPnqDL9xg9606	intact-crc:79B59272CFDFA9D8|rigid:Q3awvhNLeJhrgkhWLmoXxOMU3ts	false	-	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)