#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P18431	uniprotkb:O77059	intact:EBI-242141|uniprotkb:O76881|uniprotkb:P23646|uniprotkb:Q27603|uniprotkb:Q27604|uniprotkb:Q27605|uniprotkb:Q8MRF7|uniprotkb:Q9NF42|uniprotkb:Q9U094|uniprotkb:Q9W4X3|ensemblmetazoa:FBpp0070449|ensemblmetazoa:FBpp0070451|ensemblmetazoa:FBpp0070452|ensemblmetazoa:FBpp0070453|ensemblmetazoa:FBpp0089158|ensemblmetazoa:FBpp0089162	intact:EBI-94117|uniprotkb:Q9TYA0|ensemblmetazoa:FBpp0083150	psi-mi:sgg_drome(display_long)|uniprotkb:sgg(gene name)|psi-mi:sgg(display_short)|uniprotkb:zw3(gene name synonym)|uniprotkb:CG2621(orf name)|uniprotkb:Protein zeste-white 3(gene name synonym)|uniprotkb:gsk3(gene name synonym)	psi-mi:cry1_drome(display_long)|uniprotkb:cry(gene name)|psi-mi:cry(display_short)|uniprotkb:Blue light photoreceptor(gene name synonym)|uniprotkb:CG3772(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Stoleru et al. (2007)	imex:IM-12012|pubmed:17418796	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1248163|imex:IM-12012-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476714.1|refseq:NP_476715.1|refseq:NP_476716.2|refseq:NP_599105.1|refseq:NP_726822.1|refseq:NP_726823.1|refseq:NP_996335.1|refseq:NP_996336.1|refseq:NP_996337.1|refseq:NP_996338.1|flybase:FBgn0003371|dip:DIP-39170N|ensemblmetazoa:FBgn0003371(gene)|ensemblmetazoa:FBtr0070466(transcript)|ensemblmetazoa:FBtr0070468(transcript)|ensemblmetazoa:FBtr0070469(transcript)|ensemblmetazoa:FBtr0070470(transcript)|ensemblmetazoa:FBtr0070472(transcript)|ensemblmetazoa:FBtr0070473(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007165"(signal transduction)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007507"(heart development)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008355"(olfactory learning)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0022416"(chaeta development)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030424"(axon)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035324"(female germline ring canal)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045169"(fusome)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046959"(habituation)|go:"GO:0048477"(oogenesis)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070884"(regulation of calcineurin-NFAT signaling cascade)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-209155|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209387|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3371453|reactome:R-DME-399956|reactome:R-DME-432553|reactome:R-DME-4641262|reactome:R-DME-5610785	refseq:NP_732407.1|flybase:FBgn0025680|ensemblmetazoa:FBgn0025680(gene)|ensemblmetazoa:FBtr0083736(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007602"(phototransduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009588"(UV-A, blue light phototransduction)|go:"GO:0009637"(response to blue light)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0009785"(blue light signaling pathway)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0009882"(blue light photoreceptor activity)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042332"(gravitaxis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048512"(circadian behavior)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050958"(magnetoreception)|go:"GO:0050980"(detection of light stimulus involved in magnetoreception)|go:"GO:0071000"(response to magnetism)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0071949"(FAD binding)|interpro:IPR002081(Cryptochrome/DNA photolyase, class 1)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|rcsb pdb:4GU5|rcsb pdb:4JZY|rcsb pdb:4K03|rcsb pdb:6WTB|reactome:R-DME-432395|reactome:R-DME-432553|reactome:R-DME-538864|dip:DIP-29424N	psi-mi:"MI:0469"(intact)	-	-	figure legend:2 D|delivery method:O77059; P18431 tranfection|expression level:O77059; P18431 over-expression|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2007/04/26	2014/10/16	rogid:sUjAtUAobW55mTZBsRiQg0K1U9o7227	rogid:oK310WTO66wYsiRt4J7d6x1EHYs7227	intact-crc:3AA1B6C3E4831127|rigid:b6qIt1jhagsH+aaRehdX7+Pt8ts	false	v5 tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P18431	uniprotkb:O77059	intact:EBI-242141|uniprotkb:O76881|uniprotkb:P23646|uniprotkb:Q27603|uniprotkb:Q27604|uniprotkb:Q27605|uniprotkb:Q8MRF7|uniprotkb:Q9NF42|uniprotkb:Q9U094|uniprotkb:Q9W4X3|ensemblmetazoa:FBpp0070449|ensemblmetazoa:FBpp0070451|ensemblmetazoa:FBpp0070452|ensemblmetazoa:FBpp0070453|ensemblmetazoa:FBpp0089158|ensemblmetazoa:FBpp0089162	intact:EBI-94117|uniprotkb:Q9TYA0|ensemblmetazoa:FBpp0083150	psi-mi:sgg_drome(display_long)|uniprotkb:sgg(gene name)|psi-mi:sgg(display_short)|uniprotkb:zw3(gene name synonym)|uniprotkb:CG2621(orf name)|uniprotkb:Protein zeste-white 3(gene name synonym)|uniprotkb:gsk3(gene name synonym)	psi-mi:cry1_drome(display_long)|uniprotkb:cry(gene name)|psi-mi:cry(display_short)|uniprotkb:Blue light photoreceptor(gene name synonym)|uniprotkb:CG3772(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Stoleru et al. (2007)	imex:IM-12012|pubmed:17418796	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1248178|imex:IM-12012-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_476714.1|refseq:NP_476715.1|refseq:NP_476716.2|refseq:NP_599105.1|refseq:NP_726822.1|refseq:NP_726823.1|refseq:NP_996335.1|refseq:NP_996336.1|refseq:NP_996337.1|refseq:NP_996338.1|flybase:FBgn0003371|dip:DIP-39170N|ensemblmetazoa:FBgn0003371(gene)|ensemblmetazoa:FBtr0070466(transcript)|ensemblmetazoa:FBtr0070468(transcript)|ensemblmetazoa:FBtr0070469(transcript)|ensemblmetazoa:FBtr0070470(transcript)|ensemblmetazoa:FBtr0070472(transcript)|ensemblmetazoa:FBtr0070473(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007051"(spindle organization)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007165"(signal transduction)|go:"GO:0007367"(segment polarity determination)|go:"GO:0007507"(heart development)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008355"(olfactory learning)|go:"GO:0008407"(chaeta morphogenesis)|go:"GO:0008587"(imaginal disc-derived wing margin morphogenesis)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0022416"(chaeta development)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0030424"(axon)|go:"GO:0030589"(pseudocleavage involved in syncytial blastoderm formation)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035293"(chitin-based larval cuticle pattern formation)|go:"GO:0035309"(wing and notum subfield formation)|go:"GO:0035324"(female germline ring canal)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045169"(fusome)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046959"(habituation)|go:"GO:0048477"(oogenesis)|go:"GO:0051124"(synaptic assembly at neuromuscular junction)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070884"(regulation of calcineurin-NFAT signaling cascade)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090163"(establishment of epithelial cell planar polarity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR039192|reactome:R-DME-195253|reactome:R-DME-196299|reactome:R-DME-209155|reactome:R-DME-209159|reactome:R-DME-209190|reactome:R-DME-209214|reactome:R-DME-209360|reactome:R-DME-209387|reactome:R-DME-209396|reactome:R-DME-209413|reactome:R-DME-209440|reactome:R-DME-209461|reactome:R-DME-3371453|reactome:R-DME-399956|reactome:R-DME-432553|reactome:R-DME-4641262|reactome:R-DME-5610785	refseq:NP_732407.1|flybase:FBgn0025680|ensemblmetazoa:FBgn0025680(gene)|ensemblmetazoa:FBtr0083736(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007602"(phototransduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008020"(G protein-coupled photoreceptor activity)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009588"(UV-A, blue light phototransduction)|go:"GO:0009637"(response to blue light)|go:"GO:0009649"(entrainment of circadian clock)|go:"GO:0009785"(blue light signaling pathway)|go:"GO:0009881"(photoreceptor activity)|go:"GO:0009882"(blue light photoreceptor activity)|go:"GO:0018298"(protein-chromophore linkage)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042332"(gravitaxis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045187"(regulation of circadian sleep/wake cycle, sleep)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048512"(circadian behavior)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050958"(magnetoreception)|go:"GO:0050980"(detection of light stimulus involved in magnetoreception)|go:"GO:0071000"(response to magnetism)|go:"GO:0071482"(cellular response to light stimulus)|go:"GO:0071949"(FAD binding)|interpro:IPR002081(Cryptochrome/DNA photolyase, class 1)|interpro:IPR005101(DNA photolyase, FAD-binding/Cryptochrome, C-terminal)|interpro:IPR006050(DNA photolyase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR036134|interpro:IPR036155|rcsb pdb:4GU5|rcsb pdb:4JZY|rcsb pdb:4K03|rcsb pdb:6WTB|reactome:R-DME-432395|reactome:R-DME-432553|reactome:R-DME-538864|dip:DIP-29424N	psi-mi:"MI:0469"(intact)	-	-	figure legend:2 E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-head)|taxid:7227(Drosophila melanogaster)	-	2007/04/26	2014/10/16	rogid:sUjAtUAobW55mTZBsRiQg0K1U9o7227	rogid:oK310WTO66wYsiRt4J7d6x1EHYs7227	intact-crc:3F593D82D7BD011A|rigid:b6qIt1jhagsH+aaRehdX7+Pt8ts	false	-	myc tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)