#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P11978	uniprotkb:P40161	intact:EBI-17237|uniprotkb:D6VSK9|ensemblfungi:YDR227W	intact:EBI-29119|uniprotkb:D6W0Y4|ensemblfungi:YNL206C	psi-mi:sir4_yeast(display_long)|uniprotkb:STE9(gene name synonym)|uniprotkb:SIR4(gene name)|psi-mi:SIR4(display_short)|uniprotkb:ASD1(gene name synonym)|uniprotkb:UTH2(gene name synonym)|uniprotkb:YDR227W(locus name)|uniprotkb:YD9934.12(orf name)|uniprotkb:Silent information regulator 4(gene name synonym)	psi-mi:rt106_yeast(display_long)|uniprotkb:Regulator of Ty1 transposition protein 106(gene name synonym)|uniprotkb:YNL206C(locus name)|uniprotkb:N1346(orf name)|uniprotkb:RTT106(gene name)|psi-mi:RTT106(display_short)	psi-mi:"MI:0096"(pull down)	Huang et al. (2007)	pubmed:17410207|imex:IM-13996|mint:MINT-5219831	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7368647|mint:MINT-4790733|imex:IM-13996-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010513.1|sgd:S000002635|ensemblfungi:YDR227W(gene)|ensemblfungi:YDR227W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR031556|rcsb pdb:1NYH|rcsb pdb:1PL5|rcsb pdb:4IAO|rcsb pdb:6QSZ|rcsb pdb:6QTM|rcsb pdb:6RR0|rcsb pdb:6RRV|dip:DIP-33N|mint:P11978|mint:MINT-4790735(identity)	refseq:NP_014193.1|sgd:S000005150|dip:DIP-4292N|mint:P40161|ensemblfungi:YNL206C(gene)|ensemblfungi:YNL206C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032196"(transposition)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR040770|interpro:IPR040993|rcsb pdb:2LH0|rcsb pdb:3FSS|rcsb pdb:3GYO|rcsb pdb:3GYP|rcsb pdb:3TO1|rcsb pdb:3TVV|rcsb pdb:3TW1|mint:MINT-4790741(identity)	-	crc64:9C698765964F094E	crc64:79CACA659A7F4F4D	figure legend:F7A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/06/05	2014/10/16	rogid:C1HZEbdzRxwODKN1FHzmhYMCl+M559292	rogid:A2isuuBEAm1qbw9kuBVV2var23M559292	intact-crc:F7C888753E86E597|rigid:fthMmITeOVS6jbBoxoDPqDIx4Aw	false	-	glutathione s tranferase tag:?-?(MINT-4790742)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P06701	uniprotkb:P40161	intact:EBI-17230|uniprotkb:D6VZ77|uniprotkb:E9P924|ensemblfungi:YLR442C	intact:EBI-29119|uniprotkb:D6W0Y4|ensemblfungi:YNL206C	psi-mi:sir3_yeast(display_long)|uniprotkb:SIR3(gene name)|psi-mi:SIR3(display_short)|uniprotkb:CMT1(gene name synonym)|uniprotkb:MAR2(gene name synonym)|uniprotkb:STE8(gene name synonym)|uniprotkb:L9753.10(orf name)|uniprotkb:YLR442C(locus name)|uniprotkb:Silent information regulator 3(gene name synonym)	psi-mi:rt106_yeast(display_long)|uniprotkb:Regulator of Ty1 transposition protein 106(gene name synonym)|uniprotkb:YNL206C(locus name)|uniprotkb:N1346(orf name)|uniprotkb:RTT106(gene name)|psi-mi:RTT106(display_short)	psi-mi:"MI:0096"(pull down)	Huang et al. (2007)	pubmed:17410207|imex:IM-13996|mint:MINT-5219831	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7368661|mint:MINT-4790754|imex:IM-13996-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013547.3|sgd:S000004434|ensemblfungi:YLR442C(gene)|ensemblfungi:YLR442C_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR020793|interpro:IPR027417|interpro:IPR041083|interpro:IPR043151|rcsb pdb:2FL7|rcsb pdb:2FVU|rcsb pdb:3OWT|rcsb pdb:3TE6|rcsb pdb:3TU4|rcsb pdb:3ZCO|rcsb pdb:4JJN|rcsb pdb:4KUD|rcsb pdb:4KUL|rcsb pdb:4LD9|rcsb pdb:4KUI|dip:DIP-595N|mint:P06701|mint:MINT-4790755(identity)	refseq:NP_014193.1|sgd:S000005150|dip:DIP-4292N|mint:P40161|ensemblfungi:YNL206C(gene)|ensemblfungi:YNL206C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032196"(transposition)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR040770|interpro:IPR040993|rcsb pdb:2LH0|rcsb pdb:3FSS|rcsb pdb:3GYO|rcsb pdb:3GYP|rcsb pdb:3TO1|rcsb pdb:3TVV|rcsb pdb:3TW1|mint:MINT-4790757(identity)	-	crc64:CA2503D7645397AC	crc64:79CACA659A7F4F4D	figure legend:F7A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/06/05	2014/10/16	rogid:M+pLXY5ZyBMA0tQaEIwTkK6U2SE559292	rogid:A2isuuBEAm1qbw9kuBVV2var23M559292	intact-crc:FAD4C6AED805CB93|rigid:to0fahuYhxmY7LTqluyuWjnS9jM	false	-	glutathione s tranferase tag:?-?(MINT-4790759)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P11978	uniprotkb:P40161	intact:EBI-17237|uniprotkb:D6VSK9|ensemblfungi:YDR227W	intact:EBI-29119|uniprotkb:D6W0Y4|ensemblfungi:YNL206C	psi-mi:sir4_yeast(display_long)|uniprotkb:STE9(gene name synonym)|uniprotkb:SIR4(gene name)|psi-mi:SIR4(display_short)|uniprotkb:ASD1(gene name synonym)|uniprotkb:UTH2(gene name synonym)|uniprotkb:YDR227W(locus name)|uniprotkb:YD9934.12(orf name)|uniprotkb:Silent information regulator 4(gene name synonym)	psi-mi:rt106_yeast(display_long)|uniprotkb:Regulator of Ty1 transposition protein 106(gene name synonym)|uniprotkb:YNL206C(locus name)|uniprotkb:N1346(orf name)|uniprotkb:RTT106(gene name)|psi-mi:RTT106(display_short)	psi-mi:"MI:0676"(tandem affinity purification)	Huang et al. (2007)	pubmed:17410207|imex:IM-13996|mint:MINT-5219831	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7368700|mint:MINT-4790764|imex:IM-13996-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_010513.1|sgd:S000002635|ensemblfungi:YDR227W(gene)|ensemblfungi:YDR227W_mRNA(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031453"(positive regulation of heterochromatin assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0034398"(telomere tethering at nuclear periphery)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|interpro:IPR031556|rcsb pdb:1NYH|rcsb pdb:1PL5|rcsb pdb:4IAO|rcsb pdb:6QSZ|rcsb pdb:6QTM|rcsb pdb:6RR0|rcsb pdb:6RRV|dip:DIP-33N|mint:P11978|mint:MINT-4790765(identity)	refseq:NP_014193.1|sgd:S000005150|dip:DIP-4292N|mint:P40161|ensemblfungi:YNL206C(gene)|ensemblfungi:YNL206C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0032196"(transposition)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR040770|interpro:IPR040993|rcsb pdb:2LH0|rcsb pdb:3FSS|rcsb pdb:3GYO|rcsb pdb:3GYP|rcsb pdb:3TO1|rcsb pdb:3TVV|rcsb pdb:3TW1|mint:MINT-4790767(identity)	-	crc64:9C698765964F094E	crc64:79CACA659A7F4F4D	figure legend:F7B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/06/05	2014/10/16	rogid:C1HZEbdzRxwODKN1FHzmhYMCl+M559292	rogid:A2isuuBEAm1qbw9kuBVV2var23M559292	intact-crc:5657B6882766BEF2|rigid:fthMmITeOVS6jbBoxoDPqDIx4Aw	false	calmodulin binding peptide plus protein a tag:?-?(MINT-4790778)	flag tag:?-?(MINT-4790769)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)