#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P53816	uniprotkb:P30153	intact:EBI-746318|uniprotkb:Q3SYI3|uniprotkb:Q9HDD1|uniprotkb:B2R7Q4|uniprotkb:B7XAK5|ensembl:ENSP00000320337|ensembl:ENSP00000389124	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:plat3_human(display_long)|uniprotkb:PLAAT3(gene name)|psi-mi:PLAAT3(display_short)|uniprotkb:Adipose-specific phospholipase A2(gene name synonym)|uniprotkb:Group XVI phospholipase A1/A2(gene name synonym)|uniprotkb:H-rev 107 protein homolog(gene name synonym)|uniprotkb:HRAS-like suppressor 1(gene name synonym)|uniprotkb:HRAS-like suppressor 3(gene name synonym)|uniprotkb:HRASLS3(gene name synonym)|uniprotkb:HREV107(gene name synonym)|uniprotkb:HREV107-3(gene name synonym)|uniprotkb:PLA2G16(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-65(gene name synonym)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Nazarenko et al. (2007)	pubmed:17374643|imex:IM-19601	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1224594|imex:IM-19601-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0030397"(membrane disassembly)|go:"GO:0036152"(phosphatidylethanolamine acyl-chain remodeling)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0046485"(ether lipid metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0052739"(phosphatidylserine 1-acylhydrolase activity)|go:"GO:0052740"(1-acyl-2-lysophosphatidylserine acylhydrolase activity)|go:"GO:0070292"(N-acylphosphatidylethanolamine metabolic process)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1903008"(organelle disassembly)|go:"GO:1904177"(regulation of adipose tissue development)|interpro:IPR007053(NC)|refseq:NP_001121675.1|refseq:NP_009000.2|ensembl:ENSG00000176485(gene)|ensembl:ENST00000323646(transcript)|ensembl:ENST00000415826(transcript)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0008970"(phospholipase A1 activity)|go:"GO:0009617"(response to bacterium)|rcsb pdb:2KYT|rcsb pdb:4DOT|rcsb pdb:4FA0|rcsb pdb:4Q95|rcsb pdb:7C3Z|rcsb pdb:7C41|reactome:R-HSA-1482788|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|refseq:XP_006718489.1	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	-	-	-	dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/04/02	2014/10/16	rogid:3l37huYE4AFXxLqXB6EOoFIg5Dk9606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	intact-crc:6DA1E0A3D11E5584|rigid:0n6UvVCmSP3nDfwLeCsWalyjhbY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53816	uniprotkb:P30153	intact:EBI-746318|uniprotkb:Q3SYI3|uniprotkb:Q9HDD1|uniprotkb:B2R7Q4|uniprotkb:B7XAK5|ensembl:ENSP00000320337|ensembl:ENSP00000389124	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:plat3_human(display_long)|uniprotkb:PLAAT3(gene name)|psi-mi:PLAAT3(display_short)|uniprotkb:Adipose-specific phospholipase A2(gene name synonym)|uniprotkb:Group XVI phospholipase A1/A2(gene name synonym)|uniprotkb:H-rev 107 protein homolog(gene name synonym)|uniprotkb:HRAS-like suppressor 1(gene name synonym)|uniprotkb:HRAS-like suppressor 3(gene name synonym)|uniprotkb:HRASLS3(gene name synonym)|uniprotkb:HREV107(gene name synonym)|uniprotkb:HREV107-3(gene name synonym)|uniprotkb:PLA2G16(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-65(gene name synonym)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nazarenko et al. (2007)	pubmed:17374643|imex:IM-19601	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1224654|imex:IM-19601-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0030397"(membrane disassembly)|go:"GO:0036152"(phosphatidylethanolamine acyl-chain remodeling)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0046485"(ether lipid metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0052739"(phosphatidylserine 1-acylhydrolase activity)|go:"GO:0052740"(1-acyl-2-lysophosphatidylserine acylhydrolase activity)|go:"GO:0070292"(N-acylphosphatidylethanolamine metabolic process)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1903008"(organelle disassembly)|go:"GO:1904177"(regulation of adipose tissue development)|interpro:IPR007053(NC)|refseq:NP_001121675.1|refseq:NP_009000.2|ensembl:ENSG00000176485(gene)|ensembl:ENST00000323646(transcript)|ensembl:ENST00000415826(transcript)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0008970"(phospholipase A1 activity)|go:"GO:0009617"(response to bacterium)|rcsb pdb:2KYT|rcsb pdb:4DOT|rcsb pdb:4FA0|rcsb pdb:4Q95|rcsb pdb:7C3Z|rcsb pdb:7C41|reactome:R-HSA-1482788|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|refseq:XP_006718489.1	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	-	-	-	figure legend:1 A, D|delivery method:P30153; P53816 transfection|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2007/04/02	2014/10/16	rogid:3l37huYE4AFXxLqXB6EOoFIg5Dk9606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	intact-crc:6BF56CEF9C47C66F|rigid:0n6UvVCmSP3nDfwLeCsWalyjhbY	false	ha tag:c-c|necessary binding region:1-10	v5 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P53816	uniprotkb:P30153	intact:EBI-746318|uniprotkb:Q3SYI3|uniprotkb:Q9HDD1|uniprotkb:B2R7Q4|uniprotkb:B7XAK5|ensembl:ENSP00000320337|ensembl:ENSP00000389124	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	psi-mi:plat3_human(display_long)|uniprotkb:PLAAT3(gene name)|psi-mi:PLAAT3(display_short)|uniprotkb:Adipose-specific phospholipase A2(gene name synonym)|uniprotkb:Group XVI phospholipase A1/A2(gene name synonym)|uniprotkb:H-rev 107 protein homolog(gene name synonym)|uniprotkb:HRAS-like suppressor 1(gene name synonym)|uniprotkb:HRAS-like suppressor 3(gene name synonym)|uniprotkb:HRASLS3(gene name synonym)|uniprotkb:HREV107(gene name synonym)|uniprotkb:HREV107-3(gene name synonym)|uniprotkb:PLA2G16(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-65(gene name synonym)	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Nazarenko et al. (2007)	pubmed:17374643|imex:IM-19601	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1224674|imex:IM-19601-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0030397"(membrane disassembly)|go:"GO:0036152"(phosphatidylethanolamine acyl-chain remodeling)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0046485"(ether lipid metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0052739"(phosphatidylserine 1-acylhydrolase activity)|go:"GO:0052740"(1-acyl-2-lysophosphatidylserine acylhydrolase activity)|go:"GO:0070292"(N-acylphosphatidylethanolamine metabolic process)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1903008"(organelle disassembly)|go:"GO:1904177"(regulation of adipose tissue development)|interpro:IPR007053(NC)|refseq:NP_001121675.1|refseq:NP_009000.2|ensembl:ENSG00000176485(gene)|ensembl:ENST00000323646(transcript)|ensembl:ENST00000415826(transcript)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0008970"(phospholipase A1 activity)|go:"GO:0009617"(response to bacterium)|rcsb pdb:2KYT|rcsb pdb:4DOT|rcsb pdb:4FA0|rcsb pdb:4Q95|rcsb pdb:7C3Z|rcsb pdb:7C41|reactome:R-HSA-1482788|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|refseq:XP_006718489.1	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	-	-	-	figure legend:1 A, D|delivery method:P30153; P53816 transfection|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40)	-	2007/04/02	2014/10/16	rogid:3l37huYE4AFXxLqXB6EOoFIg5Dk9606	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	intact-crc:C8615ADA1C3A4E81|rigid:0n6UvVCmSP3nDfwLeCsWalyjhbY	false	ha tag:c-c|necessary binding region:1-10	v5 tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P30153	uniprotkb:P53816	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-746318|uniprotkb:Q3SYI3|uniprotkb:Q9HDD1|uniprotkb:B2R7Q4|uniprotkb:B7XAK5|ensembl:ENSP00000320337|ensembl:ENSP00000389124	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:plat3_human(display_long)|uniprotkb:PLAAT3(gene name)|psi-mi:PLAAT3(display_short)|uniprotkb:Adipose-specific phospholipase A2(gene name synonym)|uniprotkb:Group XVI phospholipase A1/A2(gene name synonym)|uniprotkb:H-rev 107 protein homolog(gene name synonym)|uniprotkb:HRAS-like suppressor 1(gene name synonym)|uniprotkb:HRAS-like suppressor 3(gene name synonym)|uniprotkb:HRASLS3(gene name synonym)|uniprotkb:HREV107(gene name synonym)|uniprotkb:HREV107-3(gene name synonym)|uniprotkb:PLA2G16(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-65(gene name synonym)	psi-mi:"MI:0096"(pull down)	Nazarenko et al. (2007)	pubmed:17374643|imex:IM-19601	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1224764|imex:IM-19601-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0030397"(membrane disassembly)|go:"GO:0036152"(phosphatidylethanolamine acyl-chain remodeling)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0046485"(ether lipid metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0052739"(phosphatidylserine 1-acylhydrolase activity)|go:"GO:0052740"(1-acyl-2-lysophosphatidylserine acylhydrolase activity)|go:"GO:0070292"(N-acylphosphatidylethanolamine metabolic process)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1903008"(organelle disassembly)|go:"GO:1904177"(regulation of adipose tissue development)|interpro:IPR007053(NC)|refseq:NP_001121675.1|refseq:NP_009000.2|ensembl:ENSG00000176485(gene)|ensembl:ENST00000323646(transcript)|ensembl:ENST00000415826(transcript)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0008970"(phospholipase A1 activity)|go:"GO:0009617"(response to bacterium)|rcsb pdb:2KYT|rcsb pdb:4DOT|rcsb pdb:4FA0|rcsb pdb:4Q95|rcsb pdb:7C3Z|rcsb pdb:7C41|reactome:R-HSA-1482788|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|refseq:XP_006718489.1	-	-	-	figure legend:1 B|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ovcar3)|taxid:9606(Homo sapiens OVCAR-3 ovarian adenocarcinoma cell line)	-	2007/04/02	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:3l37huYE4AFXxLqXB6EOoFIg5Dk9606	intact-crc:E1EAAFFFE2FF0F07|rigid:0n6UvVCmSP3nDfwLeCsWalyjhbY	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P30153	uniprotkb:P53816	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-746318|uniprotkb:Q3SYI3|uniprotkb:Q9HDD1|uniprotkb:B2R7Q4|uniprotkb:B7XAK5|ensembl:ENSP00000320337|ensembl:ENSP00000389124	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:plat3_human(display_long)|uniprotkb:PLAAT3(gene name)|psi-mi:PLAAT3(display_short)|uniprotkb:Adipose-specific phospholipase A2(gene name synonym)|uniprotkb:Group XVI phospholipase A1/A2(gene name synonym)|uniprotkb:H-rev 107 protein homolog(gene name synonym)|uniprotkb:HRAS-like suppressor 1(gene name synonym)|uniprotkb:HRAS-like suppressor 3(gene name synonym)|uniprotkb:HRASLS3(gene name synonym)|uniprotkb:HREV107(gene name synonym)|uniprotkb:HREV107-3(gene name synonym)|uniprotkb:PLA2G16(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-65(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Nazarenko et al. (2007)	pubmed:17374643|imex:IM-19601	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1224790|imex:IM-19601-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0030397"(membrane disassembly)|go:"GO:0036152"(phosphatidylethanolamine acyl-chain remodeling)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0046485"(ether lipid metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0052739"(phosphatidylserine 1-acylhydrolase activity)|go:"GO:0052740"(1-acyl-2-lysophosphatidylserine acylhydrolase activity)|go:"GO:0070292"(N-acylphosphatidylethanolamine metabolic process)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1903008"(organelle disassembly)|go:"GO:1904177"(regulation of adipose tissue development)|interpro:IPR007053(NC)|refseq:NP_001121675.1|refseq:NP_009000.2|ensembl:ENSG00000176485(gene)|ensembl:ENST00000323646(transcript)|ensembl:ENST00000415826(transcript)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0008970"(phospholipase A1 activity)|go:"GO:0009617"(response to bacterium)|rcsb pdb:2KYT|rcsb pdb:4DOT|rcsb pdb:4FA0|rcsb pdb:4Q95|rcsb pdb:7C3Z|rcsb pdb:7C41|reactome:R-HSA-1482788|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|refseq:XP_006718489.1	-	-	-	figure legend:2 D|expression level:P53816 was over-expressed|delivery method:P53816 transfection|comment:The proteins B56 and PR36 also coprecipitate with PR65alpha but the antibodies used were not isoform-specific.|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ovcar3)|taxid:9606(Homo sapiens OVCAR-3 ovarian adenocarcinoma cell line)	-	2007/04/02	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:3l37huYE4AFXxLqXB6EOoFIg5Dk9606	intact-crc:5297E1E33BB9BCD8|rigid:0n6UvVCmSP3nDfwLeCsWalyjhbY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P30153	uniprotkb:P53816	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-746318|uniprotkb:Q3SYI3|uniprotkb:Q9HDD1|uniprotkb:B2R7Q4|uniprotkb:B7XAK5|ensembl:ENSP00000320337|ensembl:ENSP00000389124	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:plat3_human(display_long)|uniprotkb:PLAAT3(gene name)|psi-mi:PLAAT3(display_short)|uniprotkb:Adipose-specific phospholipase A2(gene name synonym)|uniprotkb:Group XVI phospholipase A1/A2(gene name synonym)|uniprotkb:H-rev 107 protein homolog(gene name synonym)|uniprotkb:HRAS-like suppressor 1(gene name synonym)|uniprotkb:HRAS-like suppressor 3(gene name synonym)|uniprotkb:HRASLS3(gene name synonym)|uniprotkb:HREV107(gene name synonym)|uniprotkb:HREV107-3(gene name synonym)|uniprotkb:PLA2G16(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-65(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Nazarenko et al. (2007)	pubmed:17374643|imex:IM-19601	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1224830|imex:IM-19601-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0030397"(membrane disassembly)|go:"GO:0036152"(phosphatidylethanolamine acyl-chain remodeling)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0046485"(ether lipid metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0052739"(phosphatidylserine 1-acylhydrolase activity)|go:"GO:0052740"(1-acyl-2-lysophosphatidylserine acylhydrolase activity)|go:"GO:0070292"(N-acylphosphatidylethanolamine metabolic process)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1903008"(organelle disassembly)|go:"GO:1904177"(regulation of adipose tissue development)|interpro:IPR007053(NC)|refseq:NP_001121675.1|refseq:NP_009000.2|ensembl:ENSG00000176485(gene)|ensembl:ENST00000323646(transcript)|ensembl:ENST00000415826(transcript)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0008970"(phospholipase A1 activity)|go:"GO:0009617"(response to bacterium)|rcsb pdb:2KYT|rcsb pdb:4DOT|rcsb pdb:4FA0|rcsb pdb:4Q95|rcsb pdb:7C3Z|rcsb pdb:7C41|reactome:R-HSA-1482788|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|refseq:XP_006718489.1	-	-	-	figure legend:2 B|expression level:P53816 was over-expressed|delivery method:P53816 transfection|comment:Analysis of the recovered protein complexes revealed the presence of the endogenous regulatory subunit PR65alpha and the overexpressed HRSL3 protein|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ovcar3)|taxid:9606(Homo sapiens OVCAR-3 ovarian adenocarcinoma cell line)	-	2007/04/02	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:3l37huYE4AFXxLqXB6EOoFIg5Dk9606	intact-crc:A56404F6A81DCB36|rigid:0n6UvVCmSP3nDfwLeCsWalyjhbY	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P30153	uniprotkb:P53816	intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804	intact:EBI-746318|uniprotkb:Q3SYI3|uniprotkb:Q9HDD1|uniprotkb:B2R7Q4|uniprotkb:B7XAK5|ensembl:ENSP00000320337|ensembl:ENSP00000389124	psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym)	psi-mi:plat3_human(display_long)|uniprotkb:PLAAT3(gene name)|psi-mi:PLAAT3(display_short)|uniprotkb:Adipose-specific phospholipase A2(gene name synonym)|uniprotkb:Group XVI phospholipase A1/A2(gene name synonym)|uniprotkb:H-rev 107 protein homolog(gene name synonym)|uniprotkb:HRAS-like suppressor 1(gene name synonym)|uniprotkb:HRAS-like suppressor 3(gene name synonym)|uniprotkb:HRASLS3(gene name synonym)|uniprotkb:HREV107(gene name synonym)|uniprotkb:HREV107-3(gene name synonym)|uniprotkb:PLA2G16(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-65(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Nazarenko et al. (2007)	pubmed:17374643|imex:IM-19601	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1224847|imex:IM-19601-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N	go:"GO:0016021"(integral component of membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016410"(N-acyltransferase activity)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0030397"(membrane disassembly)|go:"GO:0036152"(phosphatidylethanolamine acyl-chain remodeling)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0046485"(ether lipid metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0052739"(phosphatidylserine 1-acylhydrolase activity)|go:"GO:0052740"(1-acyl-2-lysophosphatidylserine acylhydrolase activity)|go:"GO:0070292"(N-acylphosphatidylethanolamine metabolic process)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0102567"|go:"GO:0102568"|go:"GO:1903008"(organelle disassembly)|go:"GO:1904177"(regulation of adipose tissue development)|interpro:IPR007053(NC)|refseq:NP_001121675.1|refseq:NP_009000.2|ensembl:ENSG00000176485(gene)|ensembl:ENST00000323646(transcript)|ensembl:ENST00000415826(transcript)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0008970"(phospholipase A1 activity)|go:"GO:0009617"(response to bacterium)|rcsb pdb:2KYT|rcsb pdb:4DOT|rcsb pdb:4FA0|rcsb pdb:4Q95|rcsb pdb:7C3Z|rcsb pdb:7C41|reactome:R-HSA-1482788|reactome:R-HSA-1482801|reactome:R-HSA-1482839|reactome:R-HSA-1482922|refseq:XP_006718489.1	go:"GO:0005737"(cytoplasm)	-	-	figure legend:2 D|dataset:Cancer - Interactions investigated in the context of cancer|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ovcar3)|taxid:9606(Homo sapiens OVCAR-3 ovarian adenocarcinoma cell line)	-	2007/04/02	2014/10/16	rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606	rogid:3l37huYE4AFXxLqXB6EOoFIg5Dk9606	intact-crc:D3CED5A812CE9095|rigid:0n6UvVCmSP3nDfwLeCsWalyjhbY	false	-	v5 tag:?-?	-	-	psi-mi:"MI:0421"(identification by antibody)	psi-mi:"MI:0421"(identification by antibody)