#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P32790	uniprotkb:P13134	intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C	intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5	psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short)	psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Mahadev et al. (2007)	pubmed:17363896|imex:IM-11142|mint:MINT-5219761	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7323370|mint:MINT-4788696|imex:IM-11142-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790|mint:MINT-4788697(identity)	interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|mint:MINT-4788698(identity)	-	crc64:7FD85AA776407624	crc64:5DCEEDADCF439C78	figure legend:F2A|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/29	2014/10/16	rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292	rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292	intact-crc:8F82D307C3DBADFB|rigid:srsqiEYxRneXO2MxhTiFerhFpJY	false	binding-associated region:495-560(MINT-4788707)	binding-associated region:775-784(MINT-4788703)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32790	uniprotkb:P06783	intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C	intact:EBI-18366|uniprotkb:D6VX23|ensemblfungi:YKL178C	psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short)	psi-mi:ste3_yeast(display_long)|uniprotkb:STE3(gene name)|psi-mi:STE3(display_short)|uniprotkb:YKL178C(locus name)	psi-mi:"MI:0077"(nuclear magnetic resonance)	Mahadev et al. (2007)	pubmed:17363896|imex:IM-11142|mint:MINT-5219761	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7323390|mint:MINT-4788711|imex:IM-11142-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790|mint:MINT-4788712(identity)	refseq:NP_012743.1|sgd:S000001661|ensemblfungi:YKL178C(gene)|ensemblfungi:YKL178C_mRNA(transcript)|go:"GO:0000750"(pheromone-dependent signal transduction involved in conjugation with cellular fusion)|go:"GO:0000755"(cytogamy)|go:"GO:0004932"(mating-type factor pheromone receptor activity)|go:"GO:0004933"(mating-type a-factor pheromone receptor activity)|go:"GO:0005775"(vacuolar lumen)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005887"(integral component of plasma membrane)|interpro:IPR001499(Fungal pheromone STE3 GPCR)|dip:DIP-1146N|mint:P06783|mint:MINT-4788717(identity)	-	crc64:7FD85AA776407624	crc64:5DBF611076B8CA91	figure legend:F2A|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/29	2014/10/16	rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292	rogid:F7LD1XL+DteOP3zzR5mbiCMBgpA559292	intact-crc:34A592F55AEDFE51|rigid:jkZ01ghb74/bEW4heM0mweelYG4	false	binding-associated region:495-560(MINT-4788713)	binding-associated region:330-339(MINT-4788718)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32790	uniprotkb:P13134	intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C	intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5	psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short)	psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Mahadev et al. (2007)	pubmed:17363896|imex:IM-11142|mint:MINT-5219761	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7323441|mint:MINT-4788740|imex:IM-11142-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790|mint:MINT-4788741(identity)	interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|mint:MINT-4788746(identity)	-	crc64:7FD85AA776407624	crc64:5DCEEDADCF439C78	figure legend:F3C|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/05/29	2014/10/16	rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292	rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292	intact-crc:CFED031776CDB29A|rigid:srsqiEYxRneXO2MxhTiFerhFpJY	false	binding-associated region:495-560(MINT-4788742)|mutation disrupting interaction:507-507(MINT-4788761)|tag:?-?(MINT-4788758)	tag:?-?(MINT-4788754)|binding-associated region:777-781(MINT-4788747)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32790	uniprotkb:P13134	intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C	intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5	psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short)	psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Mahadev et al. (2007)	pubmed:17363896|imex:IM-11142|mint:MINT-5219761	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7323503|mint:MINT-4788787|imex:IM-11142-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790|mint:MINT-4788795(identity)	interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|mint:MINT-4788788(identity)	-	crc64:7FD85AA776407624	crc64:5DCEEDADCF439C78	figure legend:F3C|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/05/29	2014/10/16	rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292	rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292	intact-crc:BE8C5C25DF522EBA|rigid:srsqiEYxRneXO2MxhTiFerhFpJY	false	binding-associated region:495-560(MINT-4788799)|mutation disrupting interaction:529-529(MINT-4788796)|tag:?-?(MINT-4788802)	tag:?-?(MINT-4788791)|binding-associated region:777-781(MINT-4788789)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13134	uniprotkb:P32790	intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5	intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C	psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym)	psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short)	psi-mi:"MI:0018"(two hybrid)	Mahadev et al. (2007)	pubmed:17363896|imex:IM-11142|mint:MINT-5219761	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7323472|mint:MINT-4788765|imex:IM-11142-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|mint:MINT-4788777(identity)	refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790|mint:MINT-4788766(identity)	-	crc64:5DCEEDADCF439C78	crc64:7FD85AA776407624	figure legend:F3C|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/05/29	2014/10/16	rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292	rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292	intact-crc:1199C0984ACE0442|rigid:srsqiEYxRneXO2MxhTiFerhFpJY	false	tag:?-?(MINT-4788780)|binding-associated region:777-781(MINT-4788782)	binding-associated region:495-560(MINT-4788774)|tag:?-?(MINT-4788772)|mutation disrupting interaction:525-525(MINT-4788767)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32790	uniprotkb:P13134	intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C	intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5	psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short)	psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Mahadev et al. (2007)	pubmed:17363896|imex:IM-11142|mint:MINT-5219761	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7323565|mint:MINT-4788809|imex:IM-11142-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790|mint:MINT-4788810(identity)	interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|mint:MINT-4788821(identity)	-	crc64:7FD85AA776407624	crc64:5DCEEDADCF439C78	figure legend:F3C|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2007/05/29	2014/10/16	rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292	rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292	intact-crc:206C082E2366C0EC|rigid:srsqiEYxRneXO2MxhTiFerhFpJY	false	tag:?-?(MINT-4788816)|binding-associated region:495-560(MINT-4788818)|mutation disrupting interaction:531-531(MINT-4788811)	tag:?-?(MINT-4788824)|binding-associated region:777-781(MINT-4788826)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32790	uniprotkb:P13134	intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C	intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5	psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short)	psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym)	psi-mi:"MI:0096"(pull down)	Mahadev et al. (2007)	pubmed:17363896|imex:IM-11142|mint:MINT-5219761	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7323674|mint:MINT-4788856|imex:IM-11142-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790|mint:MINT-4788857(identity)	interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|mint:MINT-4788865(identity)	-	crc64:7FD85AA776407624	crc64:5DCEEDADCF439C78	figure legend:F3D|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/29	2014/10/16	rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292	rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292	intact-crc:85EBD80E3A210474|rigid:srsqiEYxRneXO2MxhTiFerhFpJY	false	mutation disrupting interaction:507-507(MINT-4788858)|binding-associated region:495-560(MINT-4788862)	binding-associated region:777-781(MINT-4788869)|glutathione s tranferase tag:?-?(MINT-4788866)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32790	uniprotkb:P13134	intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C	intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5	psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short)	psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym)	psi-mi:"MI:0096"(pull down)	Mahadev et al. (2007)	pubmed:17363896|imex:IM-11142|mint:MINT-5219761	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7323606|mint:MINT-4788831|imex:IM-11142-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790|mint:MINT-4788839(identity)	interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|mint:MINT-4788832(identity)	-	crc64:7FD85AA776407624	crc64:5DCEEDADCF439C78	figure legend:F3D|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/29	2014/10/16	rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292	rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292	intact-crc:FE73E32C11F71F48|rigid:srsqiEYxRneXO2MxhTiFerhFpJY	false	mutation decreasing interaction:525-525(MINT-4788840)|binding-associated region:495-560(MINT-4788843)	glutathione s tranferase tag:?-?(MINT-4788835)|binding-associated region:777-781(MINT-4788833)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32790	uniprotkb:P13134	intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C	intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5	psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short)	psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym)	psi-mi:"MI:0096"(pull down)	Mahadev et al. (2007)	pubmed:17363896|imex:IM-11142|mint:MINT-5219761	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7323730|mint:MINT-4788891|imex:IM-11142-10	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790|mint:MINT-4788892(identity)	interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|mint:MINT-4788900(identity)	-	crc64:7FD85AA776407624	crc64:5DCEEDADCF439C78	figure legend:F3D|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/29	2014/10/16	rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292	rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292	intact-crc:08B7E4700FF5999B|rigid:srsqiEYxRneXO2MxhTiFerhFpJY	false	mutation disrupting interaction:531-531(MINT-4788893)|binding-associated region:495-560(MINT-4788897)	glutathione s tranferase tag:?-?(MINT-4788901)|binding-associated region:777-781(MINT-4788904)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32790	uniprotkb:P13134	intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C	intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5	psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short)	psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym)	psi-mi:"MI:0096"(pull down)	Mahadev et al. (2007)	pubmed:17363896|imex:IM-11142|mint:MINT-5219761	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7323702|mint:MINT-4788873|imex:IM-11142-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790|mint:MINT-4788880(identity)	interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|mint:MINT-4788874(identity)	-	crc64:7FD85AA776407624	crc64:5DCEEDADCF439C78	figure legend:F3D|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/29	2014/10/16	rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292	rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292	intact-crc:F44681612BE4D28E|rigid:srsqiEYxRneXO2MxhTiFerhFpJY	false	binding-associated region:495-560(MINT-4788884)|mutation decreasing interaction:529-529(MINT-4788881)	binding-associated region:777-781(MINT-4788875)|glutathione s tranferase tag:?-?(MINT-4788878)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32790	uniprotkb:P13134	intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C	intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5	psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short)	psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Mahadev et al. (2007)	pubmed:17363896|imex:IM-11142|mint:MINT-5219761	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7323795|mint:MINT-4788935|imex:IM-11142-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790|mint:MINT-4788940(identity)	interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|mint:MINT-4788936(identity)	-	crc64:7FD85AA776407624	crc64:5DCEEDADCF439C78	figure legend:F3A|figure legend:F3B|kinetics:kd 6,2 nanomolar|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/29	2014/10/16	rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292	rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292	intact-crc:CD9880C0E863E2C1|rigid:srsqiEYxRneXO2MxhTiFerhFpJY	false	mutation disrupting interaction:507-507(MINT-4788945)|binding-associated region:495-560(MINT-4788942)	binding-associated region:777-781(MINT-4788938)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32790	uniprotkb:P13134	intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C	intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5	psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short)	psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Mahadev et al. (2007)	pubmed:17363896|imex:IM-11142|mint:MINT-5219761	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7323768|mint:MINT-4788908|imex:IM-11142-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790|mint:MINT-4788915(identity)	interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|mint:MINT-4788909(identity)	-	crc64:7FD85AA776407624	crc64:5DCEEDADCF439C78	figure legend:F3A|figure legend:F3B|kinetics:kd 6,2 nanomolar|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/29	2014/10/16	rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292	rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292	intact-crc:8236921DCD2B7F70|rigid:srsqiEYxRneXO2MxhTiFerhFpJY	false	mutation disrupting interaction:531-531(MINT-4788916)|binding-associated region:495-560(MINT-4788919)	binding-associated region:777-781(MINT-4788910)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13134	uniprotkb:P32790	intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5	intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C	psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym)	psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Mahadev et al. (2007)	pubmed:17363896|imex:IM-11142|mint:MINT-5219761	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7323870|mint:MINT-4788969|imex:IM-11142-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|mint:MINT-4788970(identity)	refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790|mint:MINT-4788974(identity)	-	crc64:5DCEEDADCF439C78	crc64:7FD85AA776407624	figure legend:F3A|figure legend:F3B|kinetics:kd 109 nanomolar|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/29	2014/10/16	rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292	rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292	intact-crc:AC36101D660F63EE|rigid:srsqiEYxRneXO2MxhTiFerhFpJY	false	binding-associated region:777-781(MINT-4788972)	mutation decreasing interaction:529-529(MINT-4788975)|binding-associated region:495-560(MINT-4788979)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13134	uniprotkb:P32790	intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5	intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C	psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym)	psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Mahadev et al. (2007)	pubmed:17363896|imex:IM-11142|mint:MINT-5219761	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7323822|mint:MINT-4788950|imex:IM-11142-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|mint:MINT-4788959(identity)	refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790|mint:MINT-4788951(identity)	-	crc64:5DCEEDADCF439C78	crc64:7FD85AA776407624	figure legend:F3A|figure legend:F3B|kinetics:kd 195 nanomolar|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/29	2014/10/16	rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292	rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292	intact-crc:CAF33D0D1D826931|rigid:srsqiEYxRneXO2MxhTiFerhFpJY	false	binding-associated region:777-781(MINT-4788960)	binding-associated region:495-560(MINT-4788955)|mutation decreasing interaction:525-525(MINT-4788952)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32790	uniprotkb:P13134	intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C	intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5	psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short)	psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Mahadev et al. (2007)	pubmed:17363896|imex:IM-11142|mint:MINT-5219761	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7323924|mint:MINT-4789011|imex:IM-11142-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790|mint:MINT-4789019(identity)	interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|mint:MINT-4789012(identity)	-	crc64:7FD85AA776407624	crc64:5DCEEDADCF439C78	figure legend:F3A|figure legend:F3B|kinetics:kd 6,2 nanomolar|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/29	2014/10/16	rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292	rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292	intact-crc:D3CBDA52A624BCCA|rigid:srsqiEYxRneXO2MxhTiFerhFpJY	false	binding-associated region:495-560(MINT-4789021)	binding-associated region:777-781(MINT-4789017)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P13134	uniprotkb:P32790	intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5	intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C	psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym)	psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Mahadev et al. (2007)	pubmed:17363896|imex:IM-11142|mint:MINT-5219761	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7323897|mint:MINT-4788988|imex:IM-11142-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|mint:MINT-4788997(identity)	refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790|mint:MINT-4788989(identity)	-	crc64:5DCEEDADCF439C78	crc64:7FD85AA776407624	figure legend:F3A|figure legend:F3B|kinetics:kd 29 nanomolar|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/29	2014/10/16	rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292	rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292	intact-crc:3284DAA1A10F2492|rigid:srsqiEYxRneXO2MxhTiFerhFpJY	false	mutation decreasing interaction:781-781(MINT-4789006)|binding-associated region:777-781(MINT-4788998)	binding-associated region:495-560(MINT-4788990)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P32790	uniprotkb:P13134	intact:EBI-17313|uniprotkb:D6VPZ3|ensemblfungi:YBL007C	intact:EBI-9658|ensemblfungi:YNL238W|uniprotkb:D6W0V5	psi-mi:sla1_yeast(display_long)|uniprotkb:YBL0321(orf name)|uniprotkb:YBL007C(locus name)|uniprotkb:SLA1(gene name)|psi-mi:SLA1(display_short)	psi-mi:kex2_yeast(display_long)|uniprotkb:KEX2(gene name)|psi-mi:KEX2(display_short)|uniprotkb:QDS1(gene name synonym)|uniprotkb:YNL238W(locus name)|uniprotkb:N1122(orf name)|uniprotkb:Protease KEX2(gene name synonym)|uniprotkb:Proteinase YSCF(gene name synonym)	psi-mi:"MI:0107"(surface plasmon resonance)	Mahadev et al. (2007)	pubmed:17363896|imex:IM-11142|mint:MINT-5219761	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7323946|mint:MINT-4789030|imex:IM-11142-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009546.1|sgd:S000000103|ensemblfungi:YBL007C(gene)|ensemblfungi:YBL007C_mRNA(transcript)|go:"GO:0000147"(actin cortical patch assembly)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005935"(cellular bud neck)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030479"(actin cortical patch)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043332"(mating projection tip)|go:"GO:0044396"(actin cortical patch organization)|go:"GO:0140224"(SLAC complex)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1990964"(actin cytoskeleton-regulatory complex)|interpro:IPR001452(Src homology-3)|interpro:IPR007131(SLA1 homology domain 1, SHD1)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029922|interpro:IPR035800|interpro:IPR035821|interpro:IPR036028|rcsb pdb:1SSH|rcsb pdb:1Z9Z|rcsb pdb:2HBP|rcsb pdb:2JT4|rcsb pdb:2V1Q|rcsb pdb:3IDW|dip:DIP-695N|mint:P32790|mint:MINT-4789031(identity)	interpro:IPR002884(Proprotein convertase, P)|interpro:IPR008979(Galactose-binding like)|ensemblfungi:YNL238W(gene)|ensemblfungi:YNL238W_mRNA(transcript)|go:"GO:0000324"(fungal-type vacuole)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007323"(peptide pheromone maturation)|go:"GO:0016020"(membrane)|go:"GO:0016485"(protein processing)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|interpro:IPR015500(Peptidase S8, subtilisin-related)|interpro:IPR022398|interpro:IPR023827|interpro:IPR023828|interpro:IPR034182|interpro:IPR036852|rcsb pdb:1OT5|rcsb pdb:1R64|rcsb pdb:2ID4|refseq:NP_014161.1|sgd:S000005182|dip:DIP-6287N|mint:P13134|mint:MINT-4789036(identity)	-	crc64:7FD85AA776407624	crc64:5DCEEDADCF439C78	figure legend:F3A|figure legend:F3B|kinetics:kd 6,2 nanomolar|comment:domino|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/29	2014/10/16	rogid:uDuhC6oqoPZrlUhxWJmBGbozCAs559292	rogid:DI29wdB9fSIOhlHVEuVoRiDbzl8559292	intact-crc:3044F879DA8E44E5|rigid:srsqiEYxRneXO2MxhTiFerhFpJY	false	binding-associated region:495-560(MINT-4789032)	binding-associated region:777-781(MINT-4789037)|mutation disrupting interaction:779-779(MINT-4789040)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)