#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q95RA8	uniprotkb:Q8T0S6	intact:EBI-143689|uniprotkb:Q9VD10|ensemblmetazoa:FBpp0083624|ensemblmetazoa:FBpp0307973|ensemblmetazoa:FBpp0311400	intact:EBI-101858|uniprotkb:Q9V8W4|ensemblmetazoa:FBpp0085688|ensemblmetazoa:FBpp0304253	psi-mi:mob1_drome(display_long)|uniprotkb:Mob as tumor suppressor protein 1(gene name synonym)|uniprotkb:mats(gene name)|psi-mi:mats(display_short)|uniprotkb:Mps one binder kinase activator-like 1(gene name synonym)|uniprotkb:CG13852(orf name)	psi-mi:hippo_drome(display_long)|uniprotkb:hpo(gene name)|psi-mi:hpo(display_short)|uniprotkb:dMST(gene name synonym)|uniprotkb:Drosophila homolog of MST1 and MST2(gene name synonym)|uniprotkb:STE20-like kinase MST(gene name synonym)|uniprotkb:CG11228(orf name)	psi-mi:"MI:0096"(pull down)	Wei et al. (2007)	pubmed:17347649|imex:IM-11430|mint:MINT-5219739	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7311935|mint:MINT-4787485|imex:IM-11430-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001287465.1|refseq:NP_651041.3|flybase:FBgn0038965|refseq:NP_001262835.1|dip:DIP-21478N|reactome:R-DME-390150|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035329"(hippo signaling)|go:"GO:0046872"(metal ion binding)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q95RA8|reactome:R-DME-2028269|reactome:R-DME-390089|reactome:R-DME-390098|ensemblmetazoa:FBgn0038965(gene)|ensemblmetazoa:FBtr0084229(transcript)|ensemblmetazoa:FBtr0337044(transcript)|ensemblmetazoa:FBtr0345205(transcript)|go:"GO:0005634"(nucleus)|mint:MINT-4787490(identity)	interpro:IPR036674|mint:Q8T0S6|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150|reactome:R-DME-451806|interpro:IPR024205|refseq:NP_611427.1|flybase:FBgn0261456|ensemblmetazoa:FBgn0261456(gene)|ensemblmetazoa:FBtr0086500(transcript)|ensemblmetazoa:FBtr0331920(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0042127"(regulation of cell population proliferation)|refseq:NP_001261092.1|dip:DIP-17921N|mint:MINT-4787486(identity)	-	-	-	figure legend:F3D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/28	2014/10/16	rogid:A3lIr3nWoKwEmmYOnduxz8tJ07c7227	rogid:KpEHzTCz7M84Nh6cjyyS55/p+XE7227	intact-crc:1CBAD0BC7DFD7F60|rigid:2jDSXW/lIbdj9JGRbfPHnb8kiHw	false	glutathione s tranferase tag:?-?(MINT-4787492)	flag tag:?-?(MINT-4787487)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q95RA8	uniprotkb:Q8T0S6	intact:EBI-143689|uniprotkb:Q9VD10|ensemblmetazoa:FBpp0083624|ensemblmetazoa:FBpp0307973|ensemblmetazoa:FBpp0311400	intact:EBI-101858|uniprotkb:Q9V8W4|ensemblmetazoa:FBpp0085688|ensemblmetazoa:FBpp0304253	psi-mi:mob1_drome(display_long)|uniprotkb:Mob as tumor suppressor protein 1(gene name synonym)|uniprotkb:mats(gene name)|psi-mi:mats(display_short)|uniprotkb:Mps one binder kinase activator-like 1(gene name synonym)|uniprotkb:CG13852(orf name)	psi-mi:hippo_drome(display_long)|uniprotkb:hpo(gene name)|psi-mi:hpo(display_short)|uniprotkb:dMST(gene name synonym)|uniprotkb:Drosophila homolog of MST1 and MST2(gene name synonym)|uniprotkb:STE20-like kinase MST(gene name synonym)|uniprotkb:CG11228(orf name)	psi-mi:"MI:0096"(pull down)	Wei et al. (2007)	pubmed:17347649|imex:IM-11430|mint:MINT-5219739	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7311988|mint:MINT-4787501|imex:IM-11430-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001287465.1|refseq:NP_651041.3|flybase:FBgn0038965|refseq:NP_001262835.1|dip:DIP-21478N|reactome:R-DME-390150|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035329"(hippo signaling)|go:"GO:0046872"(metal ion binding)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q95RA8|reactome:R-DME-2028269|reactome:R-DME-390089|reactome:R-DME-390098|ensemblmetazoa:FBgn0038965(gene)|ensemblmetazoa:FBtr0084229(transcript)|ensemblmetazoa:FBtr0337044(transcript)|ensemblmetazoa:FBtr0345205(transcript)|go:"GO:0005634"(nucleus)|mint:MINT-4787507(identity)	interpro:IPR036674|mint:Q8T0S6|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150|reactome:R-DME-451806|interpro:IPR024205|refseq:NP_611427.1|flybase:FBgn0261456|ensemblmetazoa:FBgn0261456(gene)|ensemblmetazoa:FBtr0086500(transcript)|ensemblmetazoa:FBtr0331920(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0042127"(regulation of cell population proliferation)|refseq:NP_001261092.1|dip:DIP-17921N|mint:MINT-4787502(identity)	-	-	-	figure legend:F3D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/28	2014/10/16	rogid:A3lIr3nWoKwEmmYOnduxz8tJ07c7227	rogid:KpEHzTCz7M84Nh6cjyyS55/p+XE7227	intact-crc:43DAB28A5081C0D7|rigid:2jDSXW/lIbdj9JGRbfPHnb8kiHw	false	glutathione s tranferase tag:?-?(MINT-4787508)	flag tag:?-?(MINT-4787505)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7L9L4	uniprotkb:P26927	intact:EBI-2558745|uniprotkb:B2R8U6|uniprotkb:Q8IY23|ensembl:ENSP00000310189|uniprotkb:B4DRY3	intact:EBI-6929133|uniprotkb:Q6GTN4|uniprotkb:A8MSX3|uniprotkb:Q14870|uniprotkb:Q13350|uniprotkb:A6NLA3	psi-mi:mob1b_human(display_long)|uniprotkb:MOB1B(gene name)|psi-mi:MOB1B(display_short)|uniprotkb:MOB4A(gene name synonym)|uniprotkb:MOBKL1A(gene name synonym)|uniprotkb:Mob1 homolog 1A(gene name synonym)|uniprotkb:Mob1B(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 1A(gene name synonym)	psi-mi:hgfl_human(display_long)|uniprotkb:D3F15S2(gene name synonym)|uniprotkb:DNF15S2(gene name synonym)|uniprotkb:HGFL(gene name synonym)|uniprotkb:Macrophage stimulatory protein(gene name synonym)|uniprotkb:Macrophage-stimulating protein(gene name synonym)|uniprotkb:MST1(gene name)|psi-mi:MST1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Wei et al. (2007)	pubmed:17347649|imex:IM-11430|mint:MINT-5219739	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7312035|mint:MINT-4787512|imex:IM-11430-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_775739.1|ensembl:ENSG00000173542(gene)|ensembl:ENST00000309395(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0019209"(kinase activator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q7L9L4|reactome:R-HSA-2028269|refseq:NP_001231695.1|refseq:XP_005265766.1|mint:MINT-4787513(identity)	go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0010758"(regulation of macrophage chemotaxis)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0035978"(histone H2A-S139 phosphorylation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:2000479"(regulation of cAMP-dependent protein kinase activity)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR024174|interpro:IPR038178|interpro:IPR043504|interpro:IPR043575|rcsb pdb:2ASU|rcsb pdb:4QT8|reactome:R-HSA-8852405|refseq:NP_066278.3|mint:P26927|dip:DIP-6028N|mint:MINT-4787517(identity)	-	-	-	figure legend:F3E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/05/28	2014/10/16	rogid:+OqB7l7K1Oax2Aj96idIAas4qT49606	rogid:CdkibLlWSzABgjln1RQ0/wPVfTc9606	intact-crc:D4E6C52563D9D53B|rigid:pMEGM19OLczsve8GjoAmqt6Xxvc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O54748	uniprotkb:Q95RA8	intact:EBI-7312078|intact:MINT-4787568	intact:EBI-143689|uniprotkb:Q9VD10|ensemblmetazoa:FBpp0083624|ensemblmetazoa:FBpp0307973|ensemblmetazoa:FBpp0311400	psi-mi:stk3_rat(display_long)|uniprotkb:Stk3(gene name)|psi-mi:Stk3(display_short)|uniprotkb:Mst2(gene name synonym)|uniprotkb:STE20-like kinase MST2(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 2(gene name synonym)	psi-mi:mob1_drome(display_long)|uniprotkb:Mob as tumor suppressor protein 1(gene name synonym)|uniprotkb:mats(gene name)|psi-mi:mats(display_short)|uniprotkb:Mps one binder kinase activator-like 1(gene name synonym)|uniprotkb:CG13852(orf name)	psi-mi:"MI:0424"(protein kinase assay)	Wei et al. (2007)	pubmed:17347649|imex:IM-11430|mint:MINT-5219739	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-7312104|mint:MINT-4787556|imex:IM-11430-3	-	-	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:O54748|refseq:NP_113923.1|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|interpro:IPR011009(Protein kinase-like)|rgd:68412|interpro:IPR000719(Protein kinase, core)|interpro:IPR011524(SARAH)|interpro:IPR036674|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001841"(neural tube formation)|go:"GO:0003157"(endocardium development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|reactome:R-RNO-2028269|mint:MINT-4787557(identity)	refseq:NP_001287465.1|refseq:NP_651041.3|flybase:FBgn0038965|refseq:NP_001262835.1|dip:DIP-21478N|reactome:R-DME-390150|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035329"(hippo signaling)|go:"GO:0046872"(metal ion binding)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q95RA8|reactome:R-DME-2028269|reactome:R-DME-390089|reactome:R-DME-390098|ensemblmetazoa:FBgn0038965(gene)|ensemblmetazoa:FBtr0084229(transcript)|ensemblmetazoa:FBtr0337044(transcript)|ensemblmetazoa:FBtr0345205(transcript)|go:"GO:0005634"(nucleus)|mint:MINT-4787561(identity)	-	function:"Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Phosphorylates and activates LATS1 and LATS2 (By similarity). Phosphorylates NKX2-1"|comment:mint	-	figure legend:F3C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/05/28	2014/10/16	rogid:Ovm8av/OP1wVd3j0wKrRBh+6EUY10116	rogid:A3lIr3nWoKwEmmYOnduxz8tJ07c7227	intact-crc:793812A60D2A14F9|rigid:sNJtwoyZp3OCgC7jYEuh1JRhAlU	false	-	glutathione s tranferase tag:?-?(MINT-4787582)	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q24590	uniprotkb:Q95RA8	intact:EBI-7312165|intact:MINT-4787599|ensemblmetazoa:FBpp0085082	intact:EBI-143689|uniprotkb:Q9VD10|ensemblmetazoa:FBpp0083624|ensemblmetazoa:FBpp0307973|ensemblmetazoa:FBpp0311400	psi-mi:q24590_drome(display_long)|uniprotkb:wts(gene name)|psi-mi:wts(display_short)|uniprotkb:CG12072(orf name)	psi-mi:mob1_drome(display_long)|uniprotkb:Mob as tumor suppressor protein 1(gene name synonym)|uniprotkb:mats(gene name)|psi-mi:mats(display_short)|uniprotkb:Mps one binder kinase activator-like 1(gene name synonym)|uniprotkb:CG13852(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wei et al. (2007)	pubmed:17347649|imex:IM-11430|mint:MINT-5219739	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7312183|mint:MINT-4787587|imex:IM-11430-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	flybase:FBgn0011739|ensemblmetazoa:FBgn0011739(gene)|ensemblmetazoa:FBtr0085720(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028742|mint:Q24590|mint:MINT-4787588(identity)	refseq:NP_001287465.1|refseq:NP_651041.3|flybase:FBgn0038965|refseq:NP_001262835.1|dip:DIP-21478N|reactome:R-DME-390150|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030707"(ovarian follicle cell development)|go:"GO:0035329"(hippo signaling)|go:"GO:0046872"(metal ion binding)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q95RA8|reactome:R-DME-2028269|reactome:R-DME-390089|reactome:R-DME-390098|ensemblmetazoa:FBgn0038965(gene)|ensemblmetazoa:FBtr0084229(transcript)|ensemblmetazoa:FBtr0337044(transcript)|ensemblmetazoa:FBtr0345205(transcript)|go:"GO:0005634"(nucleus)|mint:MINT-4787592(identity)	-	comment:mint	-	figure legend:F5A|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/05/28	2014/10/16	rogid:Du003gt8i/mHXPYtbizbt9NkZ3U7227	rogid:A3lIr3nWoKwEmmYOnduxz8tJ07c7227	intact-crc:282343F3C327FBDE|rigid:w0KEyke22p9Rs6newAqCgWnZ07s	false	myc tag:?-?(MINT-4787618)	ha tag:?-?(MINT-4787621)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q24590	uniprotkb:Q8T0S6	intact:EBI-7312165|intact:MINT-4787599|ensemblmetazoa:FBpp0085082	intact:EBI-101858|uniprotkb:Q9V8W4|ensemblmetazoa:FBpp0085688|ensemblmetazoa:FBpp0304253	psi-mi:q24590_drome(display_long)|uniprotkb:wts(gene name)|psi-mi:wts(display_short)|uniprotkb:CG12072(orf name)	psi-mi:hippo_drome(display_long)|uniprotkb:hpo(gene name)|psi-mi:hpo(display_short)|uniprotkb:dMST(gene name synonym)|uniprotkb:Drosophila homolog of MST1 and MST2(gene name synonym)|uniprotkb:STE20-like kinase MST(gene name synonym)|uniprotkb:CG11228(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wei et al. (2007)	pubmed:17347649|imex:IM-11430|mint:MINT-5219739	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7312201|mint:MINT-4787624|imex:IM-11430-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	flybase:FBgn0011739|ensemblmetazoa:FBgn0011739(gene)|ensemblmetazoa:FBtr0085720(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028742|mint:Q24590|mint:MINT-4787630(identity)	interpro:IPR036674|mint:Q8T0S6|rcsb pdb:6BN1|reactome:R-DME-390089|reactome:R-DME-390098|reactome:R-DME-390150|reactome:R-DME-451806|interpro:IPR024205|refseq:NP_611427.1|flybase:FBgn0261456|ensemblmetazoa:FBgn0261456(gene)|ensemblmetazoa:FBtr0086500(transcript)|ensemblmetazoa:FBtr0331920(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001745"(compound eye morphogenesis)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007298"(border follicle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035265"(organ growth)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045464"(R8 cell fate specification)|go:"GO:0046666"(retinal cell programmed cell death)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0072089"(stem cell proliferation)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0106037"(apicomedial cortex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|go:"GO:0042127"(regulation of cell population proliferation)|refseq:NP_001261092.1|dip:DIP-17921N|mint:MINT-4787625(identity)	-	comment:mint	-	figure legend:F5C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/05/28	2014/10/16	rogid:Du003gt8i/mHXPYtbizbt9NkZ3U7227	rogid:KpEHzTCz7M84Nh6cjyyS55/p+XE7227	intact-crc:4A63CA5B60026D43|rigid:DDB9WckhnF7nYkz1gExo8rZfKJg	false	myc tag:?-?(MINT-4787632)	flag tag:?-?(MINT-4787626)	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)