#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q01105 uniprotkb:Q6ZWX6 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1202234|uniprotkb:Q3TIQ0|ensembl:ENSMUSP00000071214 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:if2a_mouse(display_long)|uniprotkb:Eif2s1(gene name)|psi-mi:Eif2s1(display_short)|uniprotkb:Eif2a(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2 subunit alpha(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_080390.1|go:"GO:0006412"(translation)|go:"GO:0007568"(aging)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043022"(ribosome binding)|go:"GO:0043558"(regulation of translational initiation in response to stress)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0044207"(translation initiation ternary complex)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0097451"(glial limiting end-foot)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|reactome:R-MMU-156827|reactome:R-MMU-381042|reactome:R-MMU-382556|reactome:R-MMU-72649|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-72731|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|ensembl:ENSMUSG00000021116(gene)|ensembl:ENSMUST00000071230(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex) psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:FKeyVi3QK42ZWZl8m/PyPoleIDQ10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q91XD4 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1371719|ensembl:ENSMUSP00000001183 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:ftcd_mouse(display_long)|uniprotkb:Ftcd(gene name)|psi-mi:Ftcd(display_short)|uniprotkb:Formiminotransferase-cyclodeaminase(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_543121.1|go:"GO:0019556"(histidine catabolic process to glutamate and formamide)|go:"GO:0019557"(histidine catabolic process to glutamate and formate)|go:"GO:0030409"(glutamate formimidoyltransferase activity)|go:"GO:0030412"(formimidoyltetrahydrofolate cyclodeaminase activity)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0035999"(tetrahydrofolate interconversion)|interpro:IPR004227(Formiminotransferase)|interpro:IPR007044(Cyclodeaminase/cyclohydrolase)|interpro:IPR012886(Formiminotransferase, N-terminal)|interpro:IPR013802(Formiminotransferase, C-terminal)|interpro:IPR022384|interpro:IPR036178|interpro:IPR037064|interpro:IPR037070|mint:Q91XD4|reactome:R-MMU-70921|go:"GO:0008017"(microtubule binding)|ensembl:ENSMUSG00000001155(gene)|ensembl:ENSMUST00000001183(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005542"(folic acid binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006548"(histidine catabolic process)|go:"GO:0007010"(cytoskeleton organization) psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:fmS6FXQI3yz+2vxw8kOD+/7xfk410090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:P17182 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-299507|ensembl:ENSMUSP00000075513|ensembl:ENSMUSP00000079727|ensembl:ENSMUSP00000157807|uniprotkb:Q99KT7|uniprotkb:Q9DCY7 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:enoa_mouse(display_long)|uniprotkb:Eno1(gene name)|psi-mi:Eno1(display_short)|uniprotkb:Eno-1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) ensembl:ENSMUSG00000059040(gene)|ensembl:ENSMUSG00000063524(gene)|ensembl:ENSMUST00000076155(transcript)|ensembl:ENSMUST00000080926(transcript)|ensembl:ENSMUST00000235307(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030426"(growth cone)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051020"(GTPase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0099738"(cell cortex region)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P17182|reactome:R-MMU-70171|reactome:R-MMU-70263|refseq:NP_001020559.1|refseq:NP_075608.2|refseq:XP_006538588.2 psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:YFpn/7GDB6vXgCYLSxvNns7FlT410090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:P39054 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-642337|uniprotkb:Q9DBE1|ensembl:ENSMUSP00000133564 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:dyn2_mouse(display_long)|uniprotkb:Dynamin UDNM(gene name synonym)|uniprotkb:Dnm2(gene name)|psi-mi:Dnm2(display_short)|uniprotkb:Dyn2(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_001240822.1|refseq:NP_001240823.1|refseq:NP_031897.2|ensembl:ENSMUSG00000033335(gene)|ensembl:ENSMUST00000172482(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035904"(aorta development)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P39054|reactome:R-MMU-166016|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-203641|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-437239|reactome:R-MMU-8856828 psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:+f91mVsvYvuhsUOSzw37RpZv/2M10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:P20029 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-772325|uniprotkb:Q3UFF2|uniprotkb:O35642|uniprotkb:Q61630|intact:EBI-4280750|ensembl:ENSMUSP00000028222|ensembl:ENSMUSP00000097747 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:bip_mouse(display_long)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_001156906.1|refseq:NP_071705.3|dip:DIP-32341N|ensembl:ENSMUSG00000026864(gene)|ensembl:ENSMUST00000028222(transcript)|ensembl:ENSMUST00000100171(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P20029|reactome:R-MMU-3371453|reactome:R-MMU-983170 psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:AyJwwnH8IAQqF/cbTn336A79MOY10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q60737 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-771698|uniprotkb:Q8R0X4|ensembl:ENSMUSP00000096829 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:csk21_mouse(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short)|uniprotkb:Ckiia(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_031814.2|refseq:XP_011237574.1|refseq:XP_006498720.1|dip:DIP-32409N|ensembl:ENSMUSG00000074698(gene)|ensembl:ENSMUST00000099224(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q60737|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751 psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:7UK+lLG3t/3xJi7CaiGSCIcxfPg10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:P11983 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-772338|uniprotkb:Q3TJ96|uniprotkb:Q3TKU1|uniprotkb:Q3U5T8|uniprotkb:Q3U7I8|uniprotkb:Q3UAA8|uniprotkb:Q3UB80|uniprotkb:Q3UE48|intact:EBI-2291308|uniprotkb:P11984|ensembl:ENSMUSP00000116108 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:tcpa_mouse(display_long)|uniprotkb:CCT-alpha(gene name synonym)|uniprotkb:Tailless complex polypeptide 1B(gene name synonym)|uniprotkb:Tcp1(gene name)|psi-mi:Tcp1(display_short)|uniprotkb:Ccta(gene name synonym)|uniprotkb:Cct1(gene name synonym)|uniprotkb:Tailless complex polypeptide 1A(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_001277641.1|refseq:NP_038714.2|dip:DIP-32342N|ensembl:ENSMUSG00000068039(gene)|ensembl:ENSMUST00000151287(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P11983|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122 psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:mSINCow3H5FzUCTXpqwkI18OI9o10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q9WUB3 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1371761|ensembl:ENSMUSP00000047564 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:pygm_mouse(display_long)|uniprotkb:Pygm(gene name)|psi-mi:Pygm(display_short)|uniprotkb:Myophosphorylase(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_035354.1|ensembl:ENSMUSG00000032648(gene)|ensembl:ENSMUST00000035269(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0010033"(response to organic substance)|go:"GO:0016208"(AMP binding)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q9WUB3|reactome:R-MMU-70221|interpro:IPR000811(Glycosyl transferase, family 35) psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:x4zEkonduA5+JUL+3XYYPIVrIaY10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:P07724 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1183810|uniprotkb:Q3TV03|uniprotkb:Q61802|uniprotkb:Q8C7C7|uniprotkb:Q8C7H3|uniprotkb:Q8CG74|ensembl:ENSMUSP00000031314 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:albu_mouse(display_long)|uniprotkb:Alb(gene name)|psi-mi:Alb(display_short)|uniprotkb:Alb1(gene name synonym)|uniprotkb:Alb-1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_033784.2|ensembl:ENSMUSG00000029368(gene)|ensembl:ENSMUST00000031314(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015643"(toxic substance binding)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0051087"(chaperone binding)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072341"(modified amino acid binding)|go:"GO:0140272"(exogenous protein binding)|go:"GO:1903981"(enterobactin binding)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|mint:P07724|reactome:R-MMU-114608|reactome:R-MMU-159418|reactome:R-MMU-189451|reactome:R-MMU-189483|reactome:R-MMU-2168880|reactome:R-MMU-381426|reactome:R-MMU-879518|reactome:R-MMU-8957275|reactome:R-MMU-8964058|reactome:R-MMU-9707564 psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:R7zO/mB332rAl8J+WrXfsHzjSYs10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q8K4B0 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1216353|uniprotkb:Q80UI1|uniprotkb:Q8K4D4|uniprotkb:Q924K9|ensembl:ENSMUSP00000009099 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:mta1_mouse(display_long)|uniprotkb:Mta1(gene name)|psi-mi:Mta1(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:XP_006515485.1|dip:DIP-38226N|ensembl:ENSMUSG00000021144(gene)|ensembl:ENSMUST00000009099(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|reactome:R-MMU-3214815|reactome:R-MMU-3232118|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006302"(double-strand break repair)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033363"(secretory granule organization)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|mint:Q8K4B0|reactome:R-MMU-73762|reactome:R-MMU-8943724 psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:5DvgpUkohteacGjUvdFq7C+fU2w10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:O88569 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-299636|ensembl:ENSMUSP00000110103|ensembl:ENSMUSP00000145028|uniprotkb:Q3UVJ5|uniprotkb:Q6PCV9|uniprotkb:Q8C2A0|uniprotkb:Q8CJ71|uniprotkb:Q91ZR9|uniprotkb:Q9R204|uniprotkb:B9EJ02 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:roa2_mouse(display_long)|uniprotkb:Hnrnpa2b1(gene name)|psi-mi:Hnrnpa2b1(display_short)|uniprotkb:Hnrpa2b1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) ensembl:ENSMUSG00000004980(gene)|ensembl:ENSMUST00000114459(transcript)|ensembl:ENSMUST00000203954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0043204"(perikaryon)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050658"(RNA transport)|go:"GO:0005634"(nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0006397"(mRNA processing)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990715"(mRNA CDS binding)|go:"GO:0016233"(telomere capping)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|go:"GO:0016363"(nuclear matrix)|interpro:IPR034486|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR034489|interpro:IPR035979|mint:O88569|reactome:R-MMU-72163|reactome:R-MMU-72203|go:"GO:0043005"(neuron projection)|refseq:NP_058086.2|refseq:NP_872591.1|refseq:XP_006506436.2|refseq:XP_006506437.2 psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:spiQ4bW/9iuXf5NMz/cdsgIWQLE10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:P56480 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-299482|ensembl:ENSMUSP00000026459|uniprotkb:Q0QEP4|uniprotkb:Q3TFD7|uniprotkb:Q3TIP9|uniprotkb:Q3TK44|uniprotkb:Q3TWD5|uniprotkb:Q3TX28|uniprotkb:Q3U6U4|uniprotkb:Q3U774|uniprotkb:Q3UB69|uniprotkb:Q3UF69|uniprotkb:Q8CI65|uniprotkb:Q8VEJ5|uniprotkb:Q9CTI7|uniprotkb:Q9CWX7 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:atpb_mouse(display_long)|uniprotkb:Atp5f1b(gene name)|psi-mi:Atp5f1b(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:Atp5b(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P56480|reactome:R-MMU-1268020|reactome:R-MMU-163210|reactome:R-MMU-8949613|interpro:IPR020003|ensembl:ENSMUSG00000025393(gene)|ensembl:ENSMUST00000026459(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0030228"(lipoprotein particle receptor activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|go:"GO:0005524"(ATP binding)|refseq:NP_058054.2 psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:ihjn7GQ1ZSBfGcfwEAYSiCIuq+410090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q9QXD6 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1371769|uniprotkb:P97323|uniprotkb:Q3UEH1|ensembl:ENSMUSP00000090564 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:f16p1_mouse(display_long)|uniprotkb:Fbp1(gene name)|psi-mi:Fbp1(display_short)|uniprotkb:Fbp(gene name synonym)|uniprotkb:D-fructose-1,6-bisphosphate 1-phosphohydrolase 1(gene name synonym)|uniprotkb:Fbp3(gene name synonym)|uniprotkb:Fructose-1,6-bisphosphatase isozyme 3(gene name synonym)|uniprotkb:Liver FBPase(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_062268.1|interpro:IPR033391|interpro:IPR044015|mint:Q9QXD6|reactome:R-MMU-70263|interpro:IPR028343|ensembl:ENSMUSG00000069805(gene)|ensembl:ENSMUST00000092888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0005986"(sucrose biosynthetic process)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0016208"(AMP binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0035690"|go:"GO:0042132"(fructose 1,6-bisphosphate 1-phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071286"(cellular response to magnesium ion)|interpro:IPR000146(Inositol phosphatase/fructose-1,6-bisphosphatase)|interpro:IPR020548 psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:cCXgNXVjuqAh+Cl2/oW8HdMRLyA10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:P60710 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-353957|ensembl:ENSMUSP00000098066|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q3TI89|uniprotkb:Q3TVP6|uniprotkb:Q64316|uniprotkb:Q6ZWM3 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:actb_mouse(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) ensembl:ENSMUSG00000029580(gene)|ensembl:ENSMUST00000100497(transcript)|refseq:NP_031419.1|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60710|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5250924|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8856828|reactome:R-MMU-9035034|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|dip:DIP-31574N psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:P63017 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:P80316 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-772379|uniprotkb:Q3TIE0|uniprotkb:Q3U530|uniprotkb:Q3UCU4|uniprotkb:Q3UJK9|uniprotkb:Q3UWA9|uniprotkb:Q542K3|uniprotkb:Q6ZQJ1|ensembl:ENSMUSP00000022842 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:tcpe_mouse(display_long)|uniprotkb:CCT-epsilon(gene name synonym)|uniprotkb:Cct5(gene name)|psi-mi:Cct5(display_short)|uniprotkb:Ccte(gene name synonym)|uniprotkb:Kiaa0098(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_031663.1|refseq:NP_001334964.1|ensembl:ENSMUSG00000022234(gene)|ensembl:ENSMUST00000022842(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012718(T-complex protein 1, epsilon subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80316|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122 psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:UpEEjKLyd92Zl4VnOTTlziuwAGA10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q8R0Y6 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-773302|ensembl:ENSMUSP00000032175|ensembl:ENSMUSP00000114304 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:al1l1_mouse(display_long)|uniprotkb:Aldh1l1(gene name)|psi-mi:Aldh1l1(display_short)|uniprotkb:Fthfd(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 1 member L1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_081682.1|refseq:XP_006505342.1|ensembl:ENSMUSG00000030088(gene)|ensembl:ENSMUST00000032175(transcript)|ensembl:ENSMUST00000130418(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0004030"("aldehyde dehydrogenase [NAD(P)+] activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009258"(10-formyltetrahydrofolate catabolic process)|go:"GO:0016155"(formyltetrahydrofolate dehydrogenase activity)|go:"GO:0016742"(hydroxymethyl-, formyl- and related transferase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033721"("aldehyde dehydrogenase (NADP+) activity")|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR001555(Phosphoribosylglycinamide formyltransferase, active site)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR011407(10-formyltetrahydrofolate dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|interpro:IPR036477|interpro:IPR036736|interpro:IPR037022|mint:Q8R0Y6|reactome:R-MMU-196757 psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:NPrpjLQwcvgssOGZORimttWUSMY10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q63836 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1371777|uniprotkb:Q8R1T6 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:sbp2_mouse(display_long)|uniprotkb:Selenbp2(gene name)|psi-mi:Selenbp2(display_short)|uniprotkb:Lpsb2(gene name synonym)|uniprotkb:56 kDa acetaminophen-binding protein(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_062287.1|interpro:IPR008826(Selenium-binding protein)|mint:Q63836|go:"GO:0001650"(fibrillar center)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008430"(selenium binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane) psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:E/xxMHifa3vpfQexdSnn7gZN9Ws10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:P42932 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-772400|ensembl:ENSMUSP00000026704 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:tcpq_mouse(display_long)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Cct8(gene name)|psi-mi:Cct8(display_short)|uniprotkb:Cctq(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_033970.3|ensembl:ENSMUSG00000025613(gene)|ensembl:ENSMUST00000026704(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P42932|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6798695|reactome:R-MMU-6814122 psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:p3GMjguKvbAdbh4NkDyU8W4nr1E10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:P80314 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-772351|uniprotkb:Q9R1U0|ensembl:ENSMUSP00000036288 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:tcpb_mouse(display_long)|uniprotkb:CCT-beta(gene name synonym)|uniprotkb:Cct2(gene name)|psi-mi:Cct2(display_short)|uniprotkb:Cctb(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_031662.2|refseq:XP_006513224.1|dip:DIP-32343N|ensembl:ENSMUSG00000034024(gene)|ensembl:ENSMUST00000047672(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80314|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6798695|reactome:R-MMU-6814122|reactome:R-MMU-9013418|reactome:R-MMU-9013422 psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:1CGHdF6g9ZqNbyRmQ5l3eUgD5Ow10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:O35654 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-643134|uniprotkb:Q99J61|ensembl:ENSMUSP00000099986 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:dpod2_mouse(display_long)|uniprotkb:DNA polymerase delta subunit p50(gene name synonym)|uniprotkb:Pold2(gene name)|psi-mi:Pold2(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371815|imex:IM-11935-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_032920.2|refseq:XP_006514650.1|ensembl:ENSMUSG00000020471(gene)|ensembl:ENSMUST00000102922(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0042575"(DNA polymerase complex)|go:"GO:0043625"(delta DNA polymerase complex)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR024826|interpro:IPR040663|interpro:IPR041863|reactome:R-MMU-110314|reactome:R-MMU-174411|reactome:R-MMU-174414|reactome:R-MMU-174417|reactome:R-MMU-174437|reactome:R-MMU-5358565|reactome:R-MMU-5358606|reactome:R-MMU-5651801|reactome:R-MMU-5656169|reactome:R-MMU-5685942|reactome:R-MMU-5696397|reactome:R-MMU-5696400|reactome:R-MMU-6782135|reactome:R-MMU-6782210|reactome:R-MMU-69091|reactome:R-MMU-69166|reactome:R-MMU-69183|go:"GO:0016035"(zeta DNA polymerase complex) psi-mi:"MI:0469"(intact) - - figure legend:Table 1|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:eDVDjCipz2OOM4K5zryjoRpB/Dc10090 intact-crc:FA22CE76A4F71267|rigid:9NyBOt6nPItDPD7ahoaEpLJHqsQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:P30280 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-847269|ensembl:ENSMUSP00000000188 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:ccnd2_mouse(display_long)|uniprotkb:Ccnd2(gene name)|psi-mi:Ccnd2(display_short)|uniprotkb:Cyl-2(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371868|imex:IM-11935-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) dip:DIP-24177N|refseq:NP_033959.1|refseq:XP_006505522.1|refseq:XP_006505523.1|ensembl:ENSMUSG00000000184(gene)|ensembl:ENSMUST00000000188(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007616"(long-term memory)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097129"(cyclin D2-CDK4 complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015451(Cyclin D)|interpro:IPR036915|interpro:IPR039361|reactome:R-MMU-69231|reactome:R-MMU-8934593 psi-mi:"MI:0469"(intact) - - figure legend:Figure 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:3E8L11TqmxDrUbvce/DdHxWkFsY10090 intact-crc:E6C5225F90ACC305|rigid:q5KTkcABHqulPxdp+j19JgVIOPM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:P80314 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-772351|uniprotkb:Q9R1U0|ensembl:ENSMUSP00000036288 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:tcpb_mouse(display_long)|uniprotkb:CCT-beta(gene name synonym)|uniprotkb:Cct2(gene name)|psi-mi:Cct2(display_short)|uniprotkb:Cctb(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371868|imex:IM-11935-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_031662.2|refseq:XP_006513224.1|dip:DIP-32343N|ensembl:ENSMUSG00000034024(gene)|ensembl:ENSMUST00000047672(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80314|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6798695|reactome:R-MMU-6814122|reactome:R-MMU-9013418|reactome:R-MMU-9013422 psi-mi:"MI:0469"(intact) - - figure legend:Figure 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:1CGHdF6g9ZqNbyRmQ5l3eUgD5Ow10090 intact-crc:E6C5225F90ACC305|rigid:q5KTkcABHqulPxdp+j19JgVIOPM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:Q60737 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-771698|uniprotkb:Q8R0X4|ensembl:ENSMUSP00000096829 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:csk21_mouse(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short)|uniprotkb:Ckiia(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371868|imex:IM-11935-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_031814.2|refseq:XP_011237574.1|refseq:XP_006498720.1|dip:DIP-32409N|ensembl:ENSMUSG00000074698(gene)|ensembl:ENSMUST00000099224(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q60737|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751 psi-mi:"MI:0469"(intact) - - figure legend:Figure 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:7UK+lLG3t/3xJi7CaiGSCIcxfPg10090 intact-crc:E6C5225F90ACC305|rigid:q5KTkcABHqulPxdp+j19JgVIOPM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:Q6ZWX6 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1202234|uniprotkb:Q3TIQ0|ensembl:ENSMUSP00000071214 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:if2a_mouse(display_long)|uniprotkb:Eif2s1(gene name)|psi-mi:Eif2s1(display_short)|uniprotkb:Eif2a(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2 subunit alpha(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371868|imex:IM-11935-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_080390.1|go:"GO:0006412"(translation)|go:"GO:0007568"(aging)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043022"(ribosome binding)|go:"GO:0043558"(regulation of translational initiation in response to stress)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0044207"(translation initiation ternary complex)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0097451"(glial limiting end-foot)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|reactome:R-MMU-156827|reactome:R-MMU-381042|reactome:R-MMU-382556|reactome:R-MMU-72649|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-72731|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|ensembl:ENSMUSG00000021116(gene)|ensembl:ENSMUST00000071230(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex) psi-mi:"MI:0469"(intact) - - figure legend:Figure 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:FKeyVi3QK42ZWZl8m/PyPoleIDQ10090 intact-crc:E6C5225F90ACC305|rigid:q5KTkcABHqulPxdp+j19JgVIOPM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:Q9WUB3 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1371761|ensembl:ENSMUSP00000047564 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:pygm_mouse(display_long)|uniprotkb:Pygm(gene name)|psi-mi:Pygm(display_short)|uniprotkb:Myophosphorylase(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371868|imex:IM-11935-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_035354.1|ensembl:ENSMUSG00000032648(gene)|ensembl:ENSMUST00000035269(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0010033"(response to organic substance)|go:"GO:0016208"(AMP binding)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q9WUB3|reactome:R-MMU-70221|interpro:IPR000811(Glycosyl transferase, family 35) psi-mi:"MI:0469"(intact) - - figure legend:Figure 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:x4zEkonduA5+JUL+3XYYPIVrIaY10090 intact-crc:E6C5225F90ACC305|rigid:q5KTkcABHqulPxdp+j19JgVIOPM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:P30285 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-847225|ensembl:ENSMUSP00000006911 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:cdk4_mouse(display_long)|uniprotkb:Cell division protein kinase 4(gene name synonym)|uniprotkb:PSK-J3(gene name synonym)|uniprotkb:CRK3(gene name synonym)|uniprotkb:Cdk4(gene name)|psi-mi:Cdk4(display_short)|uniprotkb:Crk3(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371868|imex:IM-11935-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) dip:DIP-194N|refseq:NP_034000.1|ensembl:ENSMUSG00000006728(gene)|ensembl:ENSMUST00000006911(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010033"(response to organic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016301"(kinase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030332"(cyclin binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097129"(cyclin D2-CDK4 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1904637"(cellular response to ionomycin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P30285|reactome:R-MMU-187577|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559585|reactome:R-MMU-3214858|reactome:R-MMU-69231|reactome:R-MMU-75815|reactome:R-MMU-8849470|reactome:R-MMU-8878166|reactome:R-MMU-9616222 psi-mi:"MI:0469"(intact) - - figure legend:Figure 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:2j9azipnmWWhh48weJ3dyrdigIE10090 intact-crc:E6C5225F90ACC305|rigid:q5KTkcABHqulPxdp+j19JgVIOPM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:O35381 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-643140|uniprotkb:P97437|ensembl:ENSMUSP00000082652 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:an32a_mouse(display_long)|uniprotkb:Potent heat-stable protein phosphatase 2A inhibitor I1PP2A(gene name synonym)|uniprotkb:Acidic nuclear phosphoprotein pp32(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)|uniprotkb:Anp32a(gene name)|psi-mi:Anp32a(display_short)|uniprotkb:Anp32(gene name synonym)|uniprotkb:Lanp(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1371868|imex:IM-11935-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_033802.2|ensembl:ENSMUSG00000032249(gene)|ensembl:ENSMUST00000085519(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:O35381|rcsb pdb:2JQD|reactome:R-MMU-450520 psi-mi:"MI:0469"(intact) - - figure legend:Figure 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:flk6xO1N5PloQyQ9bOBHDzr3Hr010090 intact-crc:E6C5225F90ACC305|rigid:q5KTkcABHqulPxdp+j19JgVIOPM false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:O88569 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-299636|ensembl:ENSMUSP00000110103|ensembl:ENSMUSP00000145028|uniprotkb:Q3UVJ5|uniprotkb:Q6PCV9|uniprotkb:Q8C2A0|uniprotkb:Q8CJ71|uniprotkb:Q91ZR9|uniprotkb:Q9R204|uniprotkb:B9EJ02 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:roa2_mouse(display_long)|uniprotkb:Hnrnpa2b1(gene name)|psi-mi:Hnrnpa2b1(display_short)|uniprotkb:Hnrpa2b1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373463|imex:IM-11935-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) ensembl:ENSMUSG00000004980(gene)|ensembl:ENSMUST00000114459(transcript)|ensembl:ENSMUST00000203954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0043204"(perikaryon)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050658"(RNA transport)|go:"GO:0005634"(nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0006397"(mRNA processing)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990715"(mRNA CDS binding)|go:"GO:0016233"(telomere capping)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|go:"GO:0016363"(nuclear matrix)|interpro:IPR034486|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR034489|interpro:IPR035979|mint:O88569|reactome:R-MMU-72163|reactome:R-MMU-72203|go:"GO:0043005"(neuron projection)|refseq:NP_058086.2|refseq:NP_872591.1|refseq:XP_006506436.2|refseq:XP_006506437.2 psi-mi:"MI:0469"(intact) - - figure legend:3B|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:spiQ4bW/9iuXf5NMz/cdsgIWQLE10090 intact-crc:D7F62E0E45F43D33|rigid:8CDs43IxttWgYP7d32mZnCAYY+g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:P80314 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-772351|uniprotkb:Q9R1U0|ensembl:ENSMUSP00000036288 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:tcpb_mouse(display_long)|uniprotkb:CCT-beta(gene name synonym)|uniprotkb:Cct2(gene name)|psi-mi:Cct2(display_short)|uniprotkb:Cctb(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373463|imex:IM-11935-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_031662.2|refseq:XP_006513224.1|dip:DIP-32343N|ensembl:ENSMUSG00000034024(gene)|ensembl:ENSMUST00000047672(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80314|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6798695|reactome:R-MMU-6814122|reactome:R-MMU-9013418|reactome:R-MMU-9013422 psi-mi:"MI:0469"(intact) - - figure legend:3B|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:1CGHdF6g9ZqNbyRmQ5l3eUgD5Ow10090 intact-crc:D7F62E0E45F43D33|rigid:8CDs43IxttWgYP7d32mZnCAYY+g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:Q6ZWX6 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1202234|uniprotkb:Q3TIQ0|ensembl:ENSMUSP00000071214 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:if2a_mouse(display_long)|uniprotkb:Eif2s1(gene name)|psi-mi:Eif2s1(display_short)|uniprotkb:Eif2a(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2 subunit alpha(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373463|imex:IM-11935-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_080390.1|go:"GO:0006412"(translation)|go:"GO:0007568"(aging)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043022"(ribosome binding)|go:"GO:0043558"(regulation of translational initiation in response to stress)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0044207"(translation initiation ternary complex)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0097451"(glial limiting end-foot)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|reactome:R-MMU-156827|reactome:R-MMU-381042|reactome:R-MMU-382556|reactome:R-MMU-72649|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-72731|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|ensembl:ENSMUSG00000021116(gene)|ensembl:ENSMUST00000071230(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex) psi-mi:"MI:0469"(intact) - - figure legend:3B|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:FKeyVi3QK42ZWZl8m/PyPoleIDQ10090 intact-crc:D7F62E0E45F43D33|rigid:8CDs43IxttWgYP7d32mZnCAYY+g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:Q60737 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-771698|uniprotkb:Q8R0X4|ensembl:ENSMUSP00000096829 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:csk21_mouse(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short)|uniprotkb:Ckiia(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373463|imex:IM-11935-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_031814.2|refseq:XP_011237574.1|refseq:XP_006498720.1|dip:DIP-32409N|ensembl:ENSMUSG00000074698(gene)|ensembl:ENSMUST00000099224(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q60737|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751 psi-mi:"MI:0469"(intact) - - figure legend:3B|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:7UK+lLG3t/3xJi7CaiGSCIcxfPg10090 intact-crc:D7F62E0E45F43D33|rigid:8CDs43IxttWgYP7d32mZnCAYY+g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:Q9WUB3 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1371761|ensembl:ENSMUSP00000047564 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:pygm_mouse(display_long)|uniprotkb:Pygm(gene name)|psi-mi:Pygm(display_short)|uniprotkb:Myophosphorylase(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373463|imex:IM-11935-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_035354.1|ensembl:ENSMUSG00000032648(gene)|ensembl:ENSMUST00000035269(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0010033"(response to organic substance)|go:"GO:0016208"(AMP binding)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q9WUB3|reactome:R-MMU-70221|interpro:IPR000811(Glycosyl transferase, family 35) psi-mi:"MI:0469"(intact) - - figure legend:3B|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:x4zEkonduA5+JUL+3XYYPIVrIaY10090 intact-crc:D7F62E0E45F43D33|rigid:8CDs43IxttWgYP7d32mZnCAYY+g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:Q9WUB3 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1371761|ensembl:ENSMUSP00000047564 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:pygm_mouse(display_long)|uniprotkb:Pygm(gene name)|psi-mi:Pygm(display_short)|uniprotkb:Myophosphorylase(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373473|imex:IM-11935-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_035354.1|ensembl:ENSMUSG00000032648(gene)|ensembl:ENSMUST00000035269(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0010033"(response to organic substance)|go:"GO:0016208"(AMP binding)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q9WUB3|reactome:R-MMU-70221|interpro:IPR000811(Glycosyl transferase, family 35) psi-mi:"MI:0469"(intact) - - figure legend:3B|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:x4zEkonduA5+JUL+3XYYPIVrIaY10090 intact-crc:59AE4680E9046368|rigid:8CDs43IxttWgYP7d32mZnCAYY+g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:P80314 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-772351|uniprotkb:Q9R1U0|ensembl:ENSMUSP00000036288 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:tcpb_mouse(display_long)|uniprotkb:CCT-beta(gene name synonym)|uniprotkb:Cct2(gene name)|psi-mi:Cct2(display_short)|uniprotkb:Cctb(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373473|imex:IM-11935-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_031662.2|refseq:XP_006513224.1|dip:DIP-32343N|ensembl:ENSMUSG00000034024(gene)|ensembl:ENSMUST00000047672(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80314|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6798695|reactome:R-MMU-6814122|reactome:R-MMU-9013418|reactome:R-MMU-9013422 psi-mi:"MI:0469"(intact) - - figure legend:3B|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:1CGHdF6g9ZqNbyRmQ5l3eUgD5Ow10090 intact-crc:59AE4680E9046368|rigid:8CDs43IxttWgYP7d32mZnCAYY+g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:Q60737 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-771698|uniprotkb:Q8R0X4|ensembl:ENSMUSP00000096829 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:csk21_mouse(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short)|uniprotkb:Ckiia(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373473|imex:IM-11935-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_031814.2|refseq:XP_011237574.1|refseq:XP_006498720.1|dip:DIP-32409N|ensembl:ENSMUSG00000074698(gene)|ensembl:ENSMUST00000099224(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q60737|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751 psi-mi:"MI:0469"(intact) - - figure legend:3B|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:7UK+lLG3t/3xJi7CaiGSCIcxfPg10090 intact-crc:59AE4680E9046368|rigid:8CDs43IxttWgYP7d32mZnCAYY+g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:Q6ZWX6 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1202234|uniprotkb:Q3TIQ0|ensembl:ENSMUSP00000071214 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:if2a_mouse(display_long)|uniprotkb:Eif2s1(gene name)|psi-mi:Eif2s1(display_short)|uniprotkb:Eif2a(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2 subunit alpha(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373473|imex:IM-11935-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_080390.1|go:"GO:0006412"(translation)|go:"GO:0007568"(aging)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043022"(ribosome binding)|go:"GO:0043558"(regulation of translational initiation in response to stress)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0044207"(translation initiation ternary complex)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0097451"(glial limiting end-foot)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|reactome:R-MMU-156827|reactome:R-MMU-381042|reactome:R-MMU-382556|reactome:R-MMU-72649|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-72731|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|ensembl:ENSMUSG00000021116(gene)|ensembl:ENSMUST00000071230(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex) psi-mi:"MI:0469"(intact) - - figure legend:3B|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:FKeyVi3QK42ZWZl8m/PyPoleIDQ10090 intact-crc:59AE4680E9046368|rigid:8CDs43IxttWgYP7d32mZnCAYY+g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:O88569 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-299636|ensembl:ENSMUSP00000110103|ensembl:ENSMUSP00000145028|uniprotkb:Q3UVJ5|uniprotkb:Q6PCV9|uniprotkb:Q8C2A0|uniprotkb:Q8CJ71|uniprotkb:Q91ZR9|uniprotkb:Q9R204|uniprotkb:B9EJ02 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:roa2_mouse(display_long)|uniprotkb:Hnrnpa2b1(gene name)|psi-mi:Hnrnpa2b1(display_short)|uniprotkb:Hnrpa2b1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373473|imex:IM-11935-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) ensembl:ENSMUSG00000004980(gene)|ensembl:ENSMUST00000114459(transcript)|ensembl:ENSMUST00000203954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0043204"(perikaryon)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050658"(RNA transport)|go:"GO:0005634"(nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0006397"(mRNA processing)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990715"(mRNA CDS binding)|go:"GO:0016233"(telomere capping)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|go:"GO:0016363"(nuclear matrix)|interpro:IPR034486|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR034489|interpro:IPR035979|mint:O88569|reactome:R-MMU-72163|reactome:R-MMU-72203|go:"GO:0043005"(neuron projection)|refseq:NP_058086.2|refseq:NP_872591.1|refseq:XP_006506436.2|refseq:XP_006506437.2 psi-mi:"MI:0469"(intact) - - figure legend:3B|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:spiQ4bW/9iuXf5NMz/cdsgIWQLE10090 intact-crc:59AE4680E9046368|rigid:8CDs43IxttWgYP7d32mZnCAYY+g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:P80314 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-772351|uniprotkb:Q9R1U0|ensembl:ENSMUSP00000036288 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:tcpb_mouse(display_long)|uniprotkb:CCT-beta(gene name synonym)|uniprotkb:Cct2(gene name)|psi-mi:Cct2(display_short)|uniprotkb:Cctb(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373482|imex:IM-11935-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_031662.2|refseq:XP_006513224.1|dip:DIP-32343N|ensembl:ENSMUSG00000034024(gene)|ensembl:ENSMUST00000047672(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80314|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6798695|reactome:R-MMU-6814122|reactome:R-MMU-9013418|reactome:R-MMU-9013422 psi-mi:"MI:0469"(intact) - - figure legend:3B|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:1CGHdF6g9ZqNbyRmQ5l3eUgD5Ow10090 intact-crc:466CA4A0CE80300D|rigid:9824RWBPO3smTl5SZLEvl4UdTm0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:Q6ZWX6 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1202234|uniprotkb:Q3TIQ0|ensembl:ENSMUSP00000071214 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:if2a_mouse(display_long)|uniprotkb:Eif2s1(gene name)|psi-mi:Eif2s1(display_short)|uniprotkb:Eif2a(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2 subunit alpha(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373482|imex:IM-11935-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_080390.1|go:"GO:0006412"(translation)|go:"GO:0007568"(aging)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043022"(ribosome binding)|go:"GO:0043558"(regulation of translational initiation in response to stress)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0044207"(translation initiation ternary complex)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0097451"(glial limiting end-foot)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|reactome:R-MMU-156827|reactome:R-MMU-381042|reactome:R-MMU-382556|reactome:R-MMU-72649|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-72731|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|ensembl:ENSMUSG00000021116(gene)|ensembl:ENSMUST00000071230(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex) psi-mi:"MI:0469"(intact) - - figure legend:3B|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:FKeyVi3QK42ZWZl8m/PyPoleIDQ10090 intact-crc:466CA4A0CE80300D|rigid:9824RWBPO3smTl5SZLEvl4UdTm0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:O88569 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-299636|ensembl:ENSMUSP00000110103|ensembl:ENSMUSP00000145028|uniprotkb:Q3UVJ5|uniprotkb:Q6PCV9|uniprotkb:Q8C2A0|uniprotkb:Q8CJ71|uniprotkb:Q91ZR9|uniprotkb:Q9R204|uniprotkb:B9EJ02 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:roa2_mouse(display_long)|uniprotkb:Hnrnpa2b1(gene name)|psi-mi:Hnrnpa2b1(display_short)|uniprotkb:Hnrpa2b1(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373482|imex:IM-11935-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) ensembl:ENSMUSG00000004980(gene)|ensembl:ENSMUST00000114459(transcript)|ensembl:ENSMUST00000203954(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0043204"(perikaryon)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050658"(RNA transport)|go:"GO:0005634"(nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0006397"(mRNA processing)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990715"(mRNA CDS binding)|go:"GO:0016233"(telomere capping)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|go:"GO:0016363"(nuclear matrix)|interpro:IPR034486|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR034489|interpro:IPR035979|mint:O88569|reactome:R-MMU-72163|reactome:R-MMU-72203|go:"GO:0043005"(neuron projection)|refseq:NP_058086.2|refseq:NP_872591.1|refseq:XP_006506436.2|refseq:XP_006506437.2 psi-mi:"MI:0469"(intact) - - figure legend:3B|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:spiQ4bW/9iuXf5NMz/cdsgIWQLE10090 intact-crc:466CA4A0CE80300D|rigid:9824RWBPO3smTl5SZLEvl4UdTm0 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:Q99LB2 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-773532|uniprotkb:Q9EQU4|uniprotkb:G3X8V7|ensembl:ENSMUSP00000022821 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:dhrs4_mouse(display_long)|uniprotkb:NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase(gene name synonym)|uniprotkb:Peroxisomal short-chain alcohol dehydrogenase(gene name synonym)|uniprotkb:NADPH-dependent retinol dehydrogenase/reductase(gene name synonym)|uniprotkb:Dhrs4(gene name)|psi-mi:Dhrs4(display_short)|uniprotkb:D14Ucla2(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_001033027.2|ensembl:ENSMUSG00000022210(gene)|ensembl:ENSMUST00000022821(transcript)|go:"GO:0000253"(3-keto sterol reductase activity)|go:"GO:0001758"(retinal dehydrogenase activity)|go:"GO:0004090"("carbonyl reductase (NADPH) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0006066"(alcohol metabolic process)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0018455"("alcohol dehydrogenase [NAD(P)+] activity")|go:"GO:0042180"(cellular ketone metabolic process)|go:"GO:0042574"(retinal metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR029511|interpro:IPR036291|mint:Q99LB2|reactome:R-MMU-5365859|reactome:R-MMU-9033241 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:sCdPaEzxYGDptr0aZXGOVvDUzHA10090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q6PHN9 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1373353|ensembl:ENSMUSP00000031492 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:rab35_mouse(display_long)|uniprotkb:Rab35(gene name)|psi-mi:Rab35(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_937806.1|dip:DIP-38238N|ensembl:ENSMUSG00000029518(gene)|ensembl:ENSMUST00000031492(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008104"(protein localization)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031253"(cell projection membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042470"(melanosome)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041815|mint:Q6PHN9|reactome:R-MMU-8854214|reactome:R-MMU-8873719|reactome:R-MMU-8876198 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:95pH+DyDjv9FcxFeMmGYoJ0KyPo10090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q60737 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-771698|uniprotkb:Q8R0X4|ensembl:ENSMUSP00000096829 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:csk21_mouse(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short)|uniprotkb:Ckiia(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_031814.2|refseq:XP_011237574.1|refseq:XP_006498720.1|dip:DIP-32409N|ensembl:ENSMUSG00000074698(gene)|ensembl:ENSMUST00000099224(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q60737|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:7UK+lLG3t/3xJi7CaiGSCIcxfPg10090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:P60710 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-353957|ensembl:ENSMUSP00000098066|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q3TI89|uniprotkb:Q3TVP6|uniprotkb:Q64316|uniprotkb:Q6ZWM3 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:actb_mouse(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) ensembl:ENSMUSG00000029580(gene)|ensembl:ENSMUST00000100497(transcript)|refseq:NP_031419.1|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60710|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5250924|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8856828|reactome:R-MMU-9035034|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|dip:DIP-31574N psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q6ZWX6 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1202234|uniprotkb:Q3TIQ0|ensembl:ENSMUSP00000071214 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:if2a_mouse(display_long)|uniprotkb:Eif2s1(gene name)|psi-mi:Eif2s1(display_short)|uniprotkb:Eif2a(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2 subunit alpha(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_080390.1|go:"GO:0006412"(translation)|go:"GO:0007568"(aging)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043022"(ribosome binding)|go:"GO:0043558"(regulation of translational initiation in response to stress)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0044207"(translation initiation ternary complex)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0097451"(glial limiting end-foot)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|reactome:R-MMU-156827|reactome:R-MMU-381042|reactome:R-MMU-382556|reactome:R-MMU-72649|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-72731|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|ensembl:ENSMUSG00000021116(gene)|ensembl:ENSMUST00000071230(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex) psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:FKeyVi3QK42ZWZl8m/PyPoleIDQ10090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:P10126 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-773865|uniprotkb:Q61511|uniprotkb:Q6ZWN2|uniprotkb:Q8BMB8|uniprotkb:Q8BVS8|uniprotkb:Q99KU5|ensembl:ENSMUSP00000042457 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:ef1a1_mouse(display_long)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Eef1a1(gene name)|psi-mi:Eef1a1(display_short)|uniprotkb:Eef1a(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) dip:DIP-46609N|refseq:NP_034236.2|ensembl:ENSMUSG00000037742(gene)|ensembl:ENSMUST00000042235(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P10126|reactome:R-MMU-156842|reactome:R-MMU-3371511|reactome:R-MMU-6798695|reactome:R-MMU-8876725 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:85G9Uje743KzA02bB/rmKuq2HbU10090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q9CZN7 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1373345|uniprotkb:Q3TFD0|uniprotkb:Q99K87|ensembl:ENSMUSP00000026470 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:glym_mouse(display_long)|uniprotkb:Shmt2(gene name)|psi-mi:Shmt2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_001239245.1|refseq:NP_082506.1|ensembl:ENSMUSG00000025403(gene)|ensembl:ENSMUST00000026470(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006545"(glycine biosynthetic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008732"(L-allo-threonine aldolase activity)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016597"(amino acid binding)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|go:"GO:0070905"(serine binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|mint:Q9CZN7|reactome:R-MMU-196757|reactome:R-MMU-9013408 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:6mpx7rcJH1OwJZvgfhWBV1eIv/M10090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:O70310 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1373336|ensembl:ENSMUSP00000021314 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:nmt1_mouse(display_long)|uniprotkb:Peptide N-myristoyltransferase 1(gene name synonym)|uniprotkb:"Myristoyl-CoA:protein N-myristoyltransferase 1"(gene name synonym)|uniprotkb:Nmt1(gene name)|psi-mi:Nmt1(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_032733.1|refseq:XP_006532508.1|ensembl:ENSMUSG00000020936(gene)|ensembl:ENSMUST00000021314(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004379"(glycylpeptide N-tetradecanoyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006499"(N-terminal protein myristoylation)|go:"GO:0018008"(N-terminal peptidyl-glycine N-myristoylation)|go:"GO:0019107"(myristoyltransferase activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0042180"(cellular ketone metabolic process)|interpro:IPR000903("Myristoyl-CoA:protein N-myristoyltransferase")|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR022676|interpro:IPR022677|interpro:IPR022678|mint:O70310|reactome:R-MMU-2514859|reactome:R-MMU-75108 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:yJWs90mEeN60lVLfkdKvMcUXceQ10090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q9JMK2 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-771709|uniprotkb:Q8R389|ensembl:ENSMUSP00000113341|ensembl:ENSMUSP00000113975 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:kc1e_mouse(display_long)|uniprotkb:Csnk1e(gene name)|psi-mi:Csnk1e(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_038795.3|refseq:NP_001276827.1|refseq:XP_017172146.1|refseq:XP_017172147.1|refseq:XP_017172148.1|dip:DIP-32410N|ensembl:ENSMUSG00000022433(gene)|ensembl:ENSMUST00000117786(transcript)|ensembl:ENSMUST00000120859(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030426"(growth cone)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048512"(circadian behavior)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1903827"|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9JMK2|reactome:R-MMU-201688|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6791226|reactome:R-MMU-8854518 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:nKEZgtfpRtaJ9U9k40s5vb8qONs10090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q6PD28 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1373328|uniprotkb:Q3V3S8|uniprotkb:Q8R342|ensembl:ENSMUSP00000025695 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:2a5b_mouse(display_long)|uniprotkb:Ppp2r5b(gene name)|psi-mi:Ppp2r5b(display_short)|uniprotkb:PP2A B subunit isoform B'-beta(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-beta(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-beta(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-beta(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_937811.1|reactome:R-MMU-389513|reactome:R-MMU-432142|reactome:R-MMU-4641262|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-5675221|reactome:R-MMU-6811558|reactome:R-MMU-68877|reactome:R-MMU-9648025|go:"GO:0010469"(regulation of signaling receptor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051388"(positive regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070317"(negative regulation of G0 to G1 transition)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|reactome:R-MMU-141444|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-2467813|reactome:R-MMU-2500257|ensembl:ENSMUSG00000024777(gene)|ensembl:ENSMUST00000025695(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction) psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:OXa1nfFknb+HjioU0UyHUDbVvWw10090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q91XD4 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1371719|ensembl:ENSMUSP00000001183 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:ftcd_mouse(display_long)|uniprotkb:Ftcd(gene name)|psi-mi:Ftcd(display_short)|uniprotkb:Formiminotransferase-cyclodeaminase(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_543121.1|go:"GO:0019556"(histidine catabolic process to glutamate and formamide)|go:"GO:0019557"(histidine catabolic process to glutamate and formate)|go:"GO:0030409"(glutamate formimidoyltransferase activity)|go:"GO:0030412"(formimidoyltetrahydrofolate cyclodeaminase activity)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0035999"(tetrahydrofolate interconversion)|interpro:IPR004227(Formiminotransferase)|interpro:IPR007044(Cyclodeaminase/cyclohydrolase)|interpro:IPR012886(Formiminotransferase, N-terminal)|interpro:IPR013802(Formiminotransferase, C-terminal)|interpro:IPR022384|interpro:IPR036178|interpro:IPR037064|interpro:IPR037070|mint:Q91XD4|reactome:R-MMU-70921|go:"GO:0008017"(microtubule binding)|ensembl:ENSMUSG00000001155(gene)|ensembl:ENSMUST00000001183(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005542"(folic acid binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006548"(histidine catabolic process)|go:"GO:0007010"(cytoskeleton organization) psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:fmS6FXQI3yz+2vxw8kOD+/7xfk410090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q9JHW4 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1373318|uniprotkb:Q6GTZ5|ensembl:ENSMUSP00000131207 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:selb_mouse(display_long)|uniprotkb:Eefsec(gene name)|psi-mi:Eefsec(display_short)|uniprotkb:Selb(gene name synonym)|uniprotkb:Elongation factor sec(gene name synonym)|uniprotkb:Eukaryotic elongation factor, selenocysteine-tRNA-specific(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_075547.1|ensembl:ENSMUSG00000033216(gene)|ensembl:ENSMUST00000165242(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001514"(selenocysteine incorporation)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR027417|mint:Q9JHW4 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:RXg5Xrtcbd2GjBwU+s6+/c4Acjo10090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:P16627 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1183684|uniprotkb:O88686|uniprotkb:Q61693|ensembl:ENSMUSP00000007248 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:hs71l_mouse(display_long)|uniprotkb:Heat shock 70 kDa-like protein 1(gene name synonym)|uniprotkb:Spermatid-specific heat shock protein 70(gene name synonym)|uniprotkb:Hspa1l(gene name)|psi-mi:Hspa1l(display_short)|uniprotkb:Hsc70t(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_038586.2|ensembl:ENSMUSG00000007033(gene)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030154"(cell differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|ensembl:ENSMUST00000007248(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|reactome:R-MMU-3371453|reactome:R-MMU-3371497|reactome:R-MMU-3371568|reactome:R-MMU-3371571 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:9AyTRM+TusngYdweWsTK46QlIgk10090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q8R516 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1373289|uniprotkb:Q52QU8|uniprotkb:Q6PEF6|uniprotkb:Q8C1N7|uniprotkb:Q8VIB4|uniprotkb:A2A9P9 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:mib2_mouse(display_long)|uniprotkb:Mib2(gene name)|psi-mi:Mib2(display_short)|uniprotkb:Skd(gene name synonym)|uniprotkb:Mind bomb homolog 2(gene name synonym)|uniprotkb:Skeletrophin(gene name synonym)|uniprotkb:Dystrophin-like protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MIB2(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) interpro:IPR036770|refseq:NP_660106.2|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR010606(Mib-herc2)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR000433(Zinc finger, ZZ-type)|refseq:NP_001243037.2|reactome:R-MMU-983168|interpro:IPR037252|interpro:IPR040847|interpro:IPR042056|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003779"(actin binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR043145 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:7Nq/iAEUOOlxuMmk/2TUshbi4T810090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:P63017 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:P39054 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-642337|uniprotkb:Q9DBE1|ensembl:ENSMUSP00000133564 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:dyn2_mouse(display_long)|uniprotkb:Dynamin UDNM(gene name synonym)|uniprotkb:Dnm2(gene name)|psi-mi:Dnm2(display_short)|uniprotkb:Dyn2(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_001240822.1|refseq:NP_001240823.1|refseq:NP_031897.2|ensembl:ENSMUSG00000033335(gene)|ensembl:ENSMUST00000172482(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0008017"(microtubule binding)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0061025"(membrane fusion)|go:"GO:0098793"(presynapse)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903526"(negative regulation of membrane tubulation)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033572"(transferrin transport)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035904"(aorta development)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050699"(WW domain binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027188|interpro:IPR027417|interpro:IPR030381|mint:P39054|reactome:R-MMU-166016|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-203641|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-437239|reactome:R-MMU-8856828 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:+f91mVsvYvuhsUOSzw37RpZv/2M10090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q9WUB3 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1371761|ensembl:ENSMUSP00000047564 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:pygm_mouse(display_long)|uniprotkb:Pygm(gene name)|psi-mi:Pygm(display_short)|uniprotkb:Myophosphorylase(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_035354.1|ensembl:ENSMUSG00000032648(gene)|ensembl:ENSMUST00000035269(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0010033"(response to organic substance)|go:"GO:0016208"(AMP binding)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q9WUB3|reactome:R-MMU-70221|interpro:IPR000811(Glycosyl transferase, family 35) psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:x4zEkonduA5+JUL+3XYYPIVrIaY10090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q62383 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1373250|uniprotkb:Q5SYM0|uniprotkb:Q6GQS3|uniprotkb:Q6ZQI0|uniprotkb:Q8BQY6|ensembl:ENSMUSP00000002121 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:spt6h_mouse(display_long)|uniprotkb:Supt6h(gene name)|psi-mi:Supt6h(display_short)|uniprotkb:Kiaa0162(gene name synonym)|uniprotkb:Supt6(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_033323.2|ensembl:ENSMUSG00000002052(gene)|ensembl:ENSMUST00000002121(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003677"(DNA binding)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034728"(nucleosome organization)|go:"GO:0035327"|go:"GO:0042393"(histone binding)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045191"(regulation of isotype switching)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0051028"(mRNA transport)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070827"(obsolete chromatin maintenance)|interpro:IPR000980(SH2 motif)|interpro:IPR003029(S1, RNA binding)|interpro:IPR006641(Resolvase, RNase H-like fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR017072(Transcription elongation factor Spt6)|interpro:IPR022967|interpro:IPR023319|interpro:IPR023323|interpro:IPR028083|interpro:IPR028088|interpro:IPR028231|interpro:IPR032706|interpro:IPR035018|interpro:IPR035019|interpro:IPR035420|interpro:IPR036860|interpro:IPR037027|interpro:IPR041692|interpro:IPR042066|mint:Q62383|reactome:R-MMU-112382|reactome:R-MMU-674695|reactome:R-MMU-75955 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:h9yOnI51aroUlQNPlgQzPlOquJs10090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q01105 uniprotkb:Q6PCM1 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1373263|uniprotkb:Q2MJQ6|uniprotkb:Q3TKW8|uniprotkb:Q3UML3|uniprotkb:Q6ZQ57|uniprotkb:Q8K2J6|uniprotkb:Q8K2K4|uniprotkb:Q8R350|ensembl:ENSMUSP00000065716|ensembl:ENSMUSP00000128789|ensembl:ENSMUSP00000145959 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:kdm3a_mouse(display_long)|uniprotkb:Jumonji domain-containing protein 1A(gene name synonym)|uniprotkb:Kdm3a(gene name)|psi-mi:Kdm3a(display_short)|uniprotkb:Jhdm2a(gene name synonym)|uniprotkb:Kiaa0742(gene name synonym)|uniprotkb:Jmjd1a(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2A(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3A"(gene name synonym) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373367|imex:IM-11935-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_001033784.2|refseq:NP_766589.1|refseq:XP_006505327.1|ensembl:ENSMUSG00000053470(gene)|ensembl:ENSMUST00000065509(transcript)|ensembl:ENSMUST00000167220(transcript)|ensembl:ENSMUST00000207023(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046293"(formaldehyde biosynthetic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|reactome:R-MMU-3214842 psi-mi:"MI:0469"(intact) - - figure legend:Table 2|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2018/04/06 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:CgPzUv3rN0twZBDJWUcH7qMeGQE10090 intact-crc:D34B9F9D391A9860|rigid:AI4G+BG3btZJ/t0Gq5J5QDzBmhw false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P00489 uniprotkb:Q01105 intact:EBI-1373425 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 psi-mi:pygm_rabit(display_long)|uniprotkb:Myophosphorylase(gene name synonym)|uniprotkb:PYGM(gene name)|psi-mi:PYGM(display_short) psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:"MI:0004"(affinity chromatography technology) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9986(rabit)|taxid:9986("Oryctolagus cuniculus (Rabbit)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1373431|imex:IM-11935-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001075653.1|dip:DIP-38240N|mint:P00489|go:"GO:0000166"(nucleotide binding)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0098723"(skeletal muscle myofibril)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|rcsb pdb:1A8I|rcsb pdb:1ABB|rcsb pdb:1AXR|rcsb pdb:1B4D|rcsb pdb:1BX3|rcsb pdb:1C50|rcsb pdb:1C8K|rcsb pdb:1C8L|rcsb pdb:1E1Y|rcsb pdb:1FS4|rcsb pdb:1FTQ|rcsb pdb:1FTW|rcsb pdb:1FTY|rcsb pdb:1FU4|rcsb pdb:1FU7|rcsb pdb:1FU8|rcsb pdb:1GFZ|rcsb pdb:1GG8|rcsb pdb:1GGN|rcsb pdb:1GPA|rcsb pdb:1GPB|rcsb pdb:1GPY|rcsb pdb:1H5U|rcsb pdb:1HLF|rcsb pdb:1K06|rcsb pdb:1K08|rcsb pdb:1KTI|rcsb pdb:1LWN|rcsb pdb:1LWO|rcsb pdb:1NOI|rcsb pdb:1NOJ|rcsb pdb:1NOK|rcsb pdb:1P29|rcsb pdb:1P2B|rcsb pdb:1P2D|rcsb pdb:1P2G|rcsb pdb:1P4G|rcsb pdb:1P4H|rcsb pdb:1P4J|rcsb pdb:1PYG|rcsb pdb:1UZU|rcsb pdb:1WUT|rcsb pdb:1WUY|rcsb pdb:1WV0|rcsb pdb:1WV1|rcsb pdb:1WW2|rcsb pdb:1WW3|rcsb pdb:1XC7|rcsb pdb:1XKX|rcsb pdb:1XL0|rcsb pdb:1XL1|rcsb pdb:1Z62|rcsb pdb:1Z6P|rcsb pdb:1Z6Q|rcsb pdb:2AMV|rcsb pdb:2F3P|rcsb pdb:2F3Q|rcsb pdb:2F3S|rcsb pdb:2F3U|rcsb pdb:2FET|rcsb pdb:2FF5|rcsb pdb:2FFR|rcsb pdb:2G9Q|rcsb pdb:2G9R|rcsb pdb:2G9U|rcsb pdb:2G9V|rcsb pdb:2GJ4|rcsb pdb:2GM9|rcsb pdb:2GPA|rcsb pdb:2GPB|rcsb pdb:2GPN|rcsb pdb:2IEG|rcsb pdb:2IEI|rcsb pdb:2OFF|rcsb pdb:2PRI|rcsb pdb:2PRJ|rcsb pdb:2PYD|rcsb pdb:2PYI|rcsb pdb:2QLM|rcsb pdb:2QLN|rcsb pdb:2QN1|rcsb pdb:2QN2|rcsb pdb:2QN3|rcsb pdb:2QN7|rcsb pdb:2QN8|rcsb pdb:2QN9|rcsb pdb:2QNB|rcsb pdb:2QRG|rcsb pdb:2QRH|rcsb pdb:2QRM|rcsb pdb:2QRP|rcsb pdb:2QRQ|rcsb pdb:2SKC|rcsb pdb:2SKD|rcsb pdb:2SKE|rcsb pdb:3AMV|rcsb pdb:3BCR|rcsb pdb:3BCS|rcsb pdb:3BCU|rcsb pdb:3BD6|rcsb pdb:3BD7|rcsb pdb:3BD8|rcsb pdb:3BDA|rcsb pdb:3CUT|rcsb pdb:3CUU|rcsb pdb:3CUV|rcsb pdb:3CUW|rcsb pdb:3E3L|rcsb pdb:3E3N|rcsb pdb:3E3O|rcsb pdb:3EBO|rcsb pdb:3EBP|rcsb pdb:3G2H|rcsb pdb:3G2I|rcsb pdb:3G2J|rcsb pdb:3G2K|rcsb pdb:3G2L|rcsb pdb:3G2N|rcsb pdb:3GPB|rcsb pdb:3L79|rcsb pdb:3L7A|rcsb pdb:3L7B|rcsb pdb:3L7C|rcsb pdb:3L7D|rcsb pdb:3MQF|rcsb pdb:3MRT|rcsb pdb:3MRV|rcsb pdb:3MRX|rcsb pdb:3MS2|rcsb pdb:3MS4|rcsb pdb:3MS7|rcsb pdb:3MSC|rcsb pdb:3MT7|rcsb pdb:3MT8|rcsb pdb:3MT9|rcsb pdb:3MTA|rcsb pdb:3MTB|rcsb pdb:3MTD|rcsb pdb:3NC4|rcsb pdb:3NP7|rcsb pdb:3NP9|rcsb pdb:3NPA|rcsb pdb:3S0J|rcsb pdb:3SYM|rcsb pdb:3SYR|rcsb pdb:3T3D|rcsb pdb:3T3E|rcsb pdb:3T3G|rcsb pdb:3T3H|rcsb pdb:3T3I|rcsb pdb:3ZCP|rcsb pdb:3ZCQ|rcsb pdb:3ZCR|rcsb pdb:3ZCS|rcsb pdb:3ZCT|rcsb pdb:3ZCU|rcsb pdb:3ZCV|rcsb pdb:4CTM|rcsb pdb:4CTN|rcsb pdb:4CTO|rcsb pdb:4EJ2|rcsb pdb:4EKE|rcsb pdb:4EKY|rcsb pdb:4EL0|rcsb pdb:4EL5|rcsb pdb:4GPB|rcsb pdb:4MHO|rcsb pdb:4MHS|rcsb pdb:4MI3|rcsb pdb:4MI6|rcsb pdb:4MI9|rcsb pdb:4MIC|rcsb pdb:4MRA|rcsb pdb:4YI3|rcsb pdb:4YI5|rcsb pdb:4YUA|rcsb pdb:4Z5X|rcsb pdb:5GPB|rcsb pdb:5JTT|rcsb pdb:5JTU|rcsb pdb:5LRC|rcsb pdb:5LRD|rcsb pdb:5LRE|rcsb pdb:5LRF|rcsb pdb:5MCB|rcsb pdb:5MEM|rcsb pdb:5O50|rcsb pdb:5O52|rcsb pdb:5O54|rcsb pdb:5O56|rcsb pdb:5OWY|rcsb pdb:5OWZ|rcsb pdb:5OX0|rcsb pdb:5OX1|rcsb pdb:5OX3|rcsb pdb:5OX4|rcsb pdb:6F3J|rcsb pdb:6F3L|rcsb pdb:6F3R|rcsb pdb:6F3S|rcsb pdb:6F3U|rcsb pdb:6GPB|rcsb pdb:6QA6|rcsb pdb:6QA7|rcsb pdb:6QA8|rcsb pdb:6R0H|rcsb pdb:6R0I|rcsb pdb:6S4H|rcsb pdb:6S4K|rcsb pdb:6S4O|rcsb pdb:6S4P|rcsb pdb:6S4R|rcsb pdb:6S51|rcsb pdb:6S52|rcsb pdb:6Y55|rcsb pdb:6Y5C|rcsb pdb:6Y5O|rcsb pdb:6YVE|rcsb pdb:7GPB|rcsb pdb:7O8E|rcsb pdb:8GPB|rcsb pdb:9GPB refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) psi-mi:"MI:0469"(intact) - - figure legend:5A|comment:"The glycogen phosphorylase (GP) was taken to be of rabbit origin since the authors state that \"Purified glycogen phosphorylases (GPs) a and b and b-casein were obtained from Sigma.\". Sigma supplies GP of rabbit origin only."|complex-properties:Only phosphorylated glycogen phosphorylase interacted with the SET protein.|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:2Qbs9Zc+YJkBsbK1/qeP9c3gjys9986 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 intact-crc:F2EB4434C029397B|rigid:0PL84JH3T+CnwWJTLuDqjZHyOCE false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01105 uniprotkb:P68400 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1373506|imex:IM-11935-8 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N psi-mi:"MI:0469"(intact) - - figure legend:5B|resulting-ptm:Phosphorylation of SET.|comment:The authors confirmed that the casein kinase 2 protein used in this study was of Human origin.|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/07/18 2014/10/16 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 intact-crc:0FA3F2E7BF48001D|rigid:wKLlwq937FVSdhWp0MzRtwvHjuU false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19139 uniprotkb:P67874 intact:EBI-1373494|uniprotkb:Q5BKC1|ensembl:ENSRNOP00000007558 intact:EBI-348189|ensembl:ENSRNOP00000001123|ensembl:ENSRNOP00000068429|uniprotkb:P07312|uniprotkb:P13862 psi-mi:csk21_rat(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short) psi-mi:csk2b_rat(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Csnk2b(gene name)|psi-mi:Csnk2b(display_short)|uniprotkb:Ck2n(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1373514|imex:IM-11935-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621663|refseq:NP_446276.1|refseq:XP_006235282.1|refseq:XP_006235283.1|reactome:R-RNO-6804756|reactome:R-RNO-6814122|reactome:R-RNO-8934903|reactome:R-RNO-8939243|reactome:R-RNO-8948751|ensembl:ENSRNOG00000005276(gene)|ensembl:ENSRNOT00000007558(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19139|rcsb pdb:2R7I|reactome:R-RNO-1483191|reactome:R-RNO-201688|reactome:R-RNO-2514853|reactome:R-RNO-445144 reactome:R-RNO-8939243|reactome:R-RNO-8948751|reactome:R-RNO-8934903|ensembl:ENSRNOG00000000847(gene)|ensembl:ENSRNOT00000001123(transcript)|ensembl:ENSRNOT00000076528(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67874|rcsb pdb:2R6M|go:"GO:0031519"(PcG protein complex)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0061154"(endothelial tube morphogenesis)|reactome:R-RNO-1483191|reactome:R-RNO-201688|reactome:R-RNO-2514853|reactome:R-RNO-445144|reactome:R-RNO-6798695|reactome:R-RNO-6804756|reactome:R-RNO-6814122|rgd:619978|refseq:NP_001030315.1|refseq:NP_112283.1 psi-mi:"MI:0469"(intact) - - figure legend:5B|resulting-ptm:Phosphorylation of SET.|comment:Purified casein kinase alpha and casein kinase beta were supplied by SIGMA and taken to be of Rat origin.|complex-properties:The authors state that the tetrameric form of casein kinase alpha/beta was used.|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/07/18 2014/10/16 rogid:igJEbVxBh30nMZF6jfiISzpHEMQ10116 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg10116 intact-crc:254A0F89B67722DC|rigid:QC3AMdYAE1IScSNKNRKpgd+YLlY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P19139 uniprotkb:Q01105 intact:EBI-1373494|uniprotkb:Q5BKC1|ensembl:ENSRNOP00000007558 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 psi-mi:csk21_rat(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short) psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:"MI:0424"(protein kinase assay) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0469"(IntAct) intact:EBI-1373514|imex:IM-11935-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rgd:621663|refseq:NP_446276.1|refseq:XP_006235282.1|refseq:XP_006235283.1|reactome:R-RNO-6804756|reactome:R-RNO-6814122|reactome:R-RNO-8934903|reactome:R-RNO-8939243|reactome:R-RNO-8948751|ensembl:ENSRNOG00000005276(gene)|ensembl:ENSRNOT00000007558(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19139|rcsb pdb:2R7I|reactome:R-RNO-1483191|reactome:R-RNO-201688|reactome:R-RNO-2514853|reactome:R-RNO-445144 refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) psi-mi:"MI:0469"(intact) - - figure legend:5B|resulting-ptm:Phosphorylation of SET.|comment:Purified casein kinase alpha and casein kinase beta were supplied by SIGMA and taken to be of Rat origin.|complex-properties:The authors state that the tetrameric form of casein kinase alpha/beta was used.|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/07/18 2014/10/16 rogid:igJEbVxBh30nMZF6jfiISzpHEMQ10116 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 intact-crc:254A0F89B67722DC|rigid:QC3AMdYAE1IScSNKNRKpgd+YLlY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9EQU5 uniprotkb:Q60737 intact:EBI-1543689|uniprotkb:Q9CY82|uniprotkb:Q9D0A9|uniprotkb:Q9Z181|uniprotkb:A2BE95|ensembl:ENSMUSP00000099930 intact:EBI-771698|uniprotkb:Q8R0X4|ensembl:ENSMUSP00000096829 psi-mi:set_mouse(display_long)|uniprotkb:Set(gene name)|psi-mi:Set(display_short)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym) psi-mi:csk21_mouse(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short)|uniprotkb:Ckiia(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1543679|imex:IM-11935-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191804.1|refseq:NP_076360.1|ensembl:ENSMUSG00000054766(gene)|ensembl:ENSMUST00000102866(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9EQU5|reactome:R-MMU-2299718|reactome:R-MMU-450520 refseq:NP_031814.2|refseq:XP_011237574.1|refseq:XP_006498720.1|dip:DIP-32409N|ensembl:ENSMUSG00000074698(gene)|ensembl:ENSMUST00000099224(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q60737|reactome:R-MMU-1483191|reactome:R-MMU-201688|reactome:R-MMU-2514853|reactome:R-MMU-445144|reactome:R-MMU-6804756|reactome:R-MMU-6814122|reactome:R-MMU-8934903|reactome:R-MMU-8939243|reactome:R-MMU-8948751 psi-mi:"MI:0469"(intact) - - figure legend:4|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:1PEoqWcGzQ6q4T2SbfswpNI2Dr810090 rogid:7UK+lLG3t/3xJi7CaiGSCIcxfPg10090 intact-crc:D7E0BFD63BE64E98|rigid:0DGd9TJmz3SzfqBFFvilSh/u3cs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9EQU5 uniprotkb:Q6ZWX6 intact:EBI-1543689|uniprotkb:Q9CY82|uniprotkb:Q9D0A9|uniprotkb:Q9Z181|uniprotkb:A2BE95|ensembl:ENSMUSP00000099930 intact:EBI-1202234|uniprotkb:Q3TIQ0|ensembl:ENSMUSP00000071214 psi-mi:set_mouse(display_long)|uniprotkb:Set(gene name)|psi-mi:Set(display_short)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym) psi-mi:if2a_mouse(display_long)|uniprotkb:Eif2s1(gene name)|psi-mi:Eif2s1(display_short)|uniprotkb:Eif2a(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2 subunit alpha(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1543679|imex:IM-11935-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191804.1|refseq:NP_076360.1|ensembl:ENSMUSG00000054766(gene)|ensembl:ENSMUST00000102866(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9EQU5|reactome:R-MMU-2299718|reactome:R-MMU-450520 refseq:NP_080390.1|go:"GO:0006412"(translation)|go:"GO:0007568"(aging)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043022"(ribosome binding)|go:"GO:0043558"(regulation of translational initiation in response to stress)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0044207"(translation initiation ternary complex)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0097451"(glial limiting end-foot)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|reactome:R-MMU-156827|reactome:R-MMU-381042|reactome:R-MMU-382556|reactome:R-MMU-72649|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-72731|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|ensembl:ENSMUSG00000021116(gene)|ensembl:ENSMUST00000071230(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex) psi-mi:"MI:0469"(intact) - - figure legend:4|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:1PEoqWcGzQ6q4T2SbfswpNI2Dr810090 rogid:FKeyVi3QK42ZWZl8m/PyPoleIDQ10090 intact-crc:D7E0BFD63BE64E98|rigid:0DGd9TJmz3SzfqBFFvilSh/u3cs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9EQU5 uniprotkb:Q9WUB3 intact:EBI-1543689|uniprotkb:Q9CY82|uniprotkb:Q9D0A9|uniprotkb:Q9Z181|uniprotkb:A2BE95|ensembl:ENSMUSP00000099930 intact:EBI-1371761|ensembl:ENSMUSP00000047564 psi-mi:set_mouse(display_long)|uniprotkb:Set(gene name)|psi-mi:Set(display_short)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym) psi-mi:pygm_mouse(display_long)|uniprotkb:Pygm(gene name)|psi-mi:Pygm(display_short)|uniprotkb:Myophosphorylase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1543679|imex:IM-11935-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191804.1|refseq:NP_076360.1|ensembl:ENSMUSG00000054766(gene)|ensembl:ENSMUST00000102866(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9EQU5|reactome:R-MMU-2299718|reactome:R-MMU-450520 refseq:NP_035354.1|ensembl:ENSMUSG00000032648(gene)|ensembl:ENSMUST00000035269(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0010033"(response to organic substance)|go:"GO:0016208"(AMP binding)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q9WUB3|reactome:R-MMU-70221|interpro:IPR000811(Glycosyl transferase, family 35) psi-mi:"MI:0469"(intact) - - figure legend:4|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:1PEoqWcGzQ6q4T2SbfswpNI2Dr810090 rogid:x4zEkonduA5+JUL+3XYYPIVrIaY10090 intact-crc:D7E0BFD63BE64E98|rigid:0DGd9TJmz3SzfqBFFvilSh/u3cs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9EQU5 uniprotkb:P80314 intact:EBI-1543689|uniprotkb:Q9CY82|uniprotkb:Q9D0A9|uniprotkb:Q9Z181|uniprotkb:A2BE95|ensembl:ENSMUSP00000099930 intact:EBI-772351|uniprotkb:Q9R1U0|ensembl:ENSMUSP00000036288 psi-mi:set_mouse(display_long)|uniprotkb:Set(gene name)|psi-mi:Set(display_short)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym) psi-mi:tcpb_mouse(display_long)|uniprotkb:CCT-beta(gene name synonym)|uniprotkb:Cct2(gene name)|psi-mi:Cct2(display_short)|uniprotkb:Cctb(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Vera et al. (2007) imex:IM-11935|pubmed:17309103 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1543679|imex:IM-11935-10 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001191804.1|refseq:NP_076360.1|ensembl:ENSMUSG00000054766(gene)|ensembl:ENSMUST00000102866(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9EQU5|reactome:R-MMU-2299718|reactome:R-MMU-450520 refseq:NP_031662.2|refseq:XP_006513224.1|dip:DIP-32343N|ensembl:ENSMUSG00000034024(gene)|ensembl:ENSMUST00000047672(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80314|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6798695|reactome:R-MMU-6814122|reactome:R-MMU-9013418|reactome:R-MMU-9013422 psi-mi:"MI:0469"(intact) - - figure legend:4|dataset:Cancer - Interactions investigated in the context of cancer|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Chromatin - Epigenetic interactions resulting in chromatin modulation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-liver)|taxid:10090(Mus musculus) - 2007/07/18 2014/10/16 rogid:1PEoqWcGzQ6q4T2SbfswpNI2Dr810090 rogid:1CGHdF6g9ZqNbyRmQ5l3eUgD5Ow10090 intact-crc:D7E0BFD63BE64E98|rigid:0DGd9TJmz3SzfqBFFvilSh/u3cs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)