#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q17390	uniprotkb:P21541	intact:EBI-1811231|uniprotkb:Q8WQ96|uniprotkb:Q9NA22|uniprotkb:O46021|uniprotkb:Q8I4A7|ensemblmetazoa:ZK520.4c.1	intact:EBI-314647|ensemblmetazoa:C08B11.1.1|ensemblmetazoa:C08B11.1.2	psi-mi:cul2_caeel(display_long)|uniprotkb:cul-2(gene name)|psi-mi:cul-2(display_short)|uniprotkb:ccd-3(gene name synonym)|uniprotkb:div-3(gene name synonym)|uniprotkb:ZK520.4(orf name)	psi-mi:zyg11_caeel(display_long)|uniprotkb:zyg-11(gene name)|psi-mi:zyg-11(display_short)|uniprotkb:C08B11.1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Vasudevan et al. (2007)	pubmed:17304241|imex:IM-11410|mint:MINT-5219657	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-1811230|imex:IM-11410-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:ZK520.4c|wormbase:ZK520.4d|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|refseq:NP_001023007.1|refseq:NP_001023008.1|wormbase:ZK520.4b|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|refseq:NP_001023009.1|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q17390|ensemblmetazoa:WBGene00000837(gene)|ensemblmetazoa:ZK520.4c.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0051232"(meiotic spindle elongation)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|reactome:R-CEL-1234176|reactome:R-CEL-8951664|reactome:R-CEL-983168	refseq:NP_495677.1|wormbase:C08B11.1|mint:P21541|ensemblmetazoa:C08B11.1.1(transcript)|ensemblmetazoa:C08B11.1.2(transcript)|ensemblmetazoa:WBGene00006996(gene)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032675|dip:DIP-25221N	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-gavid adult)|taxid:6239(Caenorhabditis elegans - pregnant adult)	-	2007/03/26	2019/10/18	rogid:tu8lXpQdjRuiQfqzLwIemns9EeM6239	rogid:IvEYs/5a9zl+UnC6/ZB36CQuuxY6239	intact-crc:0F80B19586AAF2A1|rigid:c+SDlG0QxvB1brjyd4z5i9x8FC0	false	flag tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q17390	uniprotkb:Q2WF59	intact:EBI-1811231|uniprotkb:Q8WQ96|uniprotkb:Q9NA22|uniprotkb:O46021|uniprotkb:Q8I4A7|ensemblmetazoa:ZK520.4c.1	intact:EBI-1811352|uniprotkb:Q2WF58|ensemblmetazoa:T24C4.6b.1	psi-mi:cul2_caeel(display_long)|uniprotkb:cul-2(gene name)|psi-mi:cul-2(display_short)|uniprotkb:ccd-3(gene name synonym)|uniprotkb:div-3(gene name synonym)|uniprotkb:ZK520.4(orf name)	psi-mi:zer1_caeel(display_long)|uniprotkb:zer-1(gene name)|psi-mi:zer-1(display_short)|uniprotkb:zyg-11-related protein(gene name synonym)|uniprotkb:T24C4.6(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Vasudevan et al. (2007)	pubmed:17304241|imex:IM-11410|mint:MINT-5219657	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-1811372|imex:IM-11410-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:ZK520.4c|wormbase:ZK520.4d|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|refseq:NP_001023007.1|refseq:NP_001023008.1|wormbase:ZK520.4b|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|refseq:NP_001023009.1|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q17390|ensemblmetazoa:WBGene00000837(gene)|ensemblmetazoa:ZK520.4c.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0051232"(meiotic spindle elongation)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|reactome:R-CEL-1234176|reactome:R-CEL-8951664|reactome:R-CEL-983168	refseq:NP_741089.2|refseq:NP_741090.3|wormbase:T24C4.6a|wormbase:T24C4.6b|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q2WF59|interpro:IPR040368|ensemblmetazoa:T24C4.6b.1(transcript)|ensemblmetazoa:WBGene00020762(gene)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)	-	-	-	figure legend:Fig 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-gavid adult)|taxid:6239(Caenorhabditis elegans - pregnant adult)	-	2007/03/26	2019/10/18	rogid:tu8lXpQdjRuiQfqzLwIemns9EeM6239	rogid:sYAPyQAgo/z/Z3djkMCnpyqQqC46239	intact-crc:F0E16613DD4F0AED|rigid:DnCaZjGb+BuJpxkPBLuAqQY8iVc	false	flag tag:c-c	-	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)
uniprotkb:Q17390	uniprotkb:P21541	intact:EBI-1811231|uniprotkb:Q8WQ96|uniprotkb:Q9NA22|uniprotkb:O46021|uniprotkb:Q8I4A7|ensemblmetazoa:ZK520.4c.1	intact:EBI-314647|ensemblmetazoa:C08B11.1.1|ensemblmetazoa:C08B11.1.2	psi-mi:cul2_caeel(display_long)|uniprotkb:cul-2(gene name)|psi-mi:cul-2(display_short)|uniprotkb:ccd-3(gene name synonym)|uniprotkb:div-3(gene name synonym)|uniprotkb:ZK520.4(orf name)	psi-mi:zyg11_caeel(display_long)|uniprotkb:zyg-11(gene name)|psi-mi:zyg-11(display_short)|uniprotkb:C08B11.1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Vasudevan et al. (2007)	pubmed:17304241|imex:IM-11410|mint:MINT-5219657	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-1811269|imex:IM-11410-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:ZK520.4c|wormbase:ZK520.4d|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|refseq:NP_001023007.1|refseq:NP_001023008.1|wormbase:ZK520.4b|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|refseq:NP_001023009.1|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q17390|ensemblmetazoa:WBGene00000837(gene)|ensemblmetazoa:ZK520.4c.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0051232"(meiotic spindle elongation)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|reactome:R-CEL-1234176|reactome:R-CEL-8951664|reactome:R-CEL-983168	refseq:NP_495677.1|wormbase:C08B11.1|mint:P21541|ensemblmetazoa:C08B11.1.1(transcript)|ensemblmetazoa:C08B11.1.2(transcript)|ensemblmetazoa:WBGene00006996(gene)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032675|dip:DIP-25221N	-	-	-	figure legend:Fig 2A|inhibition:Interaction between cul-2 and zyg-11 is inhibited by RNAi against elc-1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:6239(caeel-gavid adult)|taxid:6239(Caenorhabditis elegans - pregnant adult)	-	2007/03/26	2019/10/18	rogid:tu8lXpQdjRuiQfqzLwIemns9EeM6239	rogid:IvEYs/5a9zl+UnC6/ZB36CQuuxY6239	intact-crc:3A459C285ACCAF31|rigid:c+SDlG0QxvB1brjyd4z5i9x8FC0	false	flag tag:c-c	-	-	-	psi-mi:"MI:0086"(polyclonal antibody western blot)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q17390	uniprotkb:Q9BKS1	intact:EBI-1811231|uniprotkb:Q8WQ96|uniprotkb:Q9NA22|uniprotkb:O46021|uniprotkb:Q8I4A7|ensemblmetazoa:ZK520.4c.1	intact:EBI-300574|ensemblmetazoa:Y82E9BR.15.1	psi-mi:cul2_caeel(display_long)|uniprotkb:cul-2(gene name)|psi-mi:cul-2(display_short)|uniprotkb:ccd-3(gene name synonym)|uniprotkb:div-3(gene name synonym)|uniprotkb:ZK520.4(orf name)	psi-mi:q9bks1_caeel(display_long)|uniprotkb:elc-1(gene name)|psi-mi:elc-1(display_short)|uniprotkb:Y82E9BR.15(orf name)|uniprotkb:CELE_Y82E9BR.15(orf name)	psi-mi:"MI:0096"(pull down)	Vasudevan et al. (2007)	pubmed:17304241|imex:IM-11410|mint:MINT-5219657	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-1811284|imex:IM-11410-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	wormbase:ZK520.4c|wormbase:ZK520.4d|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR001373(Cullin, N-terminal region)|refseq:NP_001023007.1|refseq:NP_001023008.1|wormbase:ZK520.4b|interpro:IPR019559|interpro:IPR016159(Cullin repeat-like)|refseq:NP_001023009.1|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q17390|ensemblmetazoa:WBGene00000837(gene)|ensemblmetazoa:ZK520.4c.1(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008104"(protein localization)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019100"(male germ-line sex determination)|go:"GO:0019102"(male somatic sex determination)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0036369"(transcription factor catabolic process)|go:"GO:0042078"(germ-line stem cell division)|go:"GO:0051232"(meiotic spindle elongation)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|reactome:R-CEL-1234176|reactome:R-CEL-8951664|reactome:R-CEL-983168	mint:Q9BKS1|ensemblmetazoa:WBGene00001236(gene)|ensemblmetazoa:Y82E9BR.15.1(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:0070449"(elongin complex)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-CEL-112382|reactome:R-CEL-1234176|reactome:R-CEL-674695|reactome:R-CEL-6796648|reactome:R-CEL-75955|reactome:R-CEL-8951664|reactome:R-CEL-983168|refseq:NP_497405.1|wormbase:Y82E9BR.15|dip:DIP-26192N	-	-	-	figure legend:Fig 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/26	2019/10/18	rogid:tu8lXpQdjRuiQfqzLwIemns9EeM6239	rogid:agsPa0MUmIQXimutXTZgAGPbAwo6239	intact-crc:9D9A9EC576260227|rigid:QVFJsRDAci+5Oghb3s+SM556LjM	false	35s radiolabel:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P21541	uniprotkb:Q9BKS1	intact:EBI-314647|ensemblmetazoa:C08B11.1.1|ensemblmetazoa:C08B11.1.2	intact:EBI-300574|ensemblmetazoa:Y82E9BR.15.1	psi-mi:zyg11_caeel(display_long)|uniprotkb:zyg-11(gene name)|psi-mi:zyg-11(display_short)|uniprotkb:C08B11.1(orf name)	psi-mi:q9bks1_caeel(display_long)|uniprotkb:elc-1(gene name)|psi-mi:elc-1(display_short)|uniprotkb:Y82E9BR.15(orf name)|uniprotkb:CELE_Y82E9BR.15(orf name)	psi-mi:"MI:0096"(pull down)	Vasudevan et al. (2007)	pubmed:17304241|imex:IM-11410|mint:MINT-5219657	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-1811301|imex:IM-11410-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_495677.1|wormbase:C08B11.1|mint:P21541|ensemblmetazoa:C08B11.1.1(transcript)|ensemblmetazoa:C08B11.1.2(transcript)|ensemblmetazoa:WBGene00006996(gene)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032675|dip:DIP-25221N	mint:Q9BKS1|ensemblmetazoa:WBGene00001236(gene)|ensemblmetazoa:Y82E9BR.15.1(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:0070449"(elongin complex)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-CEL-112382|reactome:R-CEL-1234176|reactome:R-CEL-674695|reactome:R-CEL-6796648|reactome:R-CEL-75955|reactome:R-CEL-8951664|reactome:R-CEL-983168|refseq:NP_497405.1|wormbase:Y82E9BR.15|dip:DIP-26192N	-	-	-	figure legend:Fig 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/26	2014/10/16	rogid:IvEYs/5a9zl+UnC6/ZB36CQuuxY6239	rogid:agsPa0MUmIQXimutXTZgAGPbAwo6239	intact-crc:3AFD5060B62A8C35|rigid:Gt3AtrQCGZYVZ5BbBv1HjwvIi3Y	false	35s radiolabel:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q9BKS1	uniprotkb:P21541	intact:EBI-300574|ensemblmetazoa:Y82E9BR.15.1	intact:EBI-314647|ensemblmetazoa:C08B11.1.1|ensemblmetazoa:C08B11.1.2	psi-mi:q9bks1_caeel(display_long)|uniprotkb:elc-1(gene name)|psi-mi:elc-1(display_short)|uniprotkb:Y82E9BR.15(orf name)|uniprotkb:CELE_Y82E9BR.15(orf name)	psi-mi:zyg11_caeel(display_long)|uniprotkb:zyg-11(gene name)|psi-mi:zyg-11(display_short)|uniprotkb:C08B11.1(orf name)	psi-mi:"MI:0018"(two hybrid)	Vasudevan et al. (2007)	pubmed:17304241|imex:IM-11410|mint:MINT-5219657	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-1811319|imex:IM-11410-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	mint:Q9BKS1|ensemblmetazoa:WBGene00001236(gene)|ensemblmetazoa:Y82E9BR.15.1(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:0070449"(elongin complex)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-CEL-112382|reactome:R-CEL-1234176|reactome:R-CEL-674695|reactome:R-CEL-6796648|reactome:R-CEL-75955|reactome:R-CEL-8951664|reactome:R-CEL-983168|refseq:NP_497405.1|wormbase:Y82E9BR.15|dip:DIP-26192N	refseq:NP_495677.1|wormbase:C08B11.1|mint:P21541|ensemblmetazoa:C08B11.1.1(transcript)|ensemblmetazoa:C08B11.1.2(transcript)|ensemblmetazoa:WBGene00006996(gene)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032675|dip:DIP-25221N	-	-	-	figure legend:Fig 2C, 3A, 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/03/26	2014/10/16	rogid:agsPa0MUmIQXimutXTZgAGPbAwo6239	rogid:IvEYs/5a9zl+UnC6/ZB36CQuuxY6239	intact-crc:89700706EEFD70FE|rigid:Gt3AtrQCGZYVZ5BbBv1HjwvIi3Y	false	-	mutation disrupting interaction:21-21|sufficient binding region:1-131|mutation disrupting interaction:18-18	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q19213	uniprotkb:Q9BKS1	intact:EBI-1811333|ensemblmetazoa:F08G12.4.1	intact:EBI-300574|ensemblmetazoa:Y82E9BR.15.1	psi-mi:vhl_caeel(display_long)|uniprotkb:vhl-1(gene name)|psi-mi:vhl-1(display_short)|uniprotkb:F08G12.4(orf name)	psi-mi:q9bks1_caeel(display_long)|uniprotkb:elc-1(gene name)|psi-mi:elc-1(display_short)|uniprotkb:Y82E9BR.15(orf name)|uniprotkb:CELE_Y82E9BR.15(orf name)	psi-mi:"MI:0018"(two hybrid)	Vasudevan et al. (2007)	pubmed:17304241|imex:IM-11410|mint:MINT-5219657	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-1811329|imex:IM-11410-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_509889.1|wormbase:F08G12.4|interpro:IPR024053|interpro:IPR022772|interpro:IPR036208|interpro:IPR037140|mint:Q19213|ensemblmetazoa:F08G12.4.1(transcript)|ensemblmetazoa:WBGene00006922(gene)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|reactome:R-CEL-1234176|reactome:R-CEL-3232142|reactome:R-CEL-8951664|reactome:R-CEL-9706019|reactome:R-CEL-983168	mint:Q9BKS1|ensemblmetazoa:WBGene00001236(gene)|ensemblmetazoa:Y82E9BR.15.1(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:0070449"(elongin complex)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-CEL-112382|reactome:R-CEL-1234176|reactome:R-CEL-674695|reactome:R-CEL-6796648|reactome:R-CEL-75955|reactome:R-CEL-8951664|reactome:R-CEL-983168|refseq:NP_497405.1|wormbase:Y82E9BR.15|dip:DIP-26192N	-	-	-	figure legend:Fig 2C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/03/26	2014/10/16	rogid:ssahaPgjW6jqdgoGQ9PJKRmEWXU6239	rogid:agsPa0MUmIQXimutXTZgAGPbAwo6239	intact-crc:4722B8A605DD0133|rigid:hQTKWgHNgxfcfm0DAFCQWHPiG5k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q2WF59	uniprotkb:Q9BKS1	intact:EBI-1811352|uniprotkb:Q2WF58|ensemblmetazoa:T24C4.6b.1	intact:EBI-300574|ensemblmetazoa:Y82E9BR.15.1	psi-mi:zer1_caeel(display_long)|uniprotkb:zer-1(gene name)|psi-mi:zer-1(display_short)|uniprotkb:zyg-11-related protein(gene name synonym)|uniprotkb:T24C4.6(orf name)	psi-mi:q9bks1_caeel(display_long)|uniprotkb:elc-1(gene name)|psi-mi:elc-1(display_short)|uniprotkb:Y82E9BR.15(orf name)|uniprotkb:CELE_Y82E9BR.15(orf name)	psi-mi:"MI:0018"(two hybrid)	Vasudevan et al. (2007)	pubmed:17304241|imex:IM-11410|mint:MINT-5219657	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-1811379|imex:IM-11410-8	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741089.2|refseq:NP_741090.3|wormbase:T24C4.6a|wormbase:T24C4.6b|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q2WF59|interpro:IPR040368|ensemblmetazoa:T24C4.6b.1(transcript)|ensemblmetazoa:WBGene00020762(gene)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)	mint:Q9BKS1|ensemblmetazoa:WBGene00001236(gene)|ensemblmetazoa:Y82E9BR.15.1(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0051759"(sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation)|go:"GO:0070449"(elongin complex)|go:"GO:1902104"(positive regulation of metaphase/anaphase transition of meiotic cell cycle)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|reactome:R-CEL-112382|reactome:R-CEL-1234176|reactome:R-CEL-674695|reactome:R-CEL-6796648|reactome:R-CEL-75955|reactome:R-CEL-8951664|reactome:R-CEL-983168|refseq:NP_497405.1|wormbase:Y82E9BR.15|dip:DIP-26192N	-	-	-	figure legend:Fig 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/03/26	2014/10/16	rogid:sYAPyQAgo/z/Z3djkMCnpyqQqC46239	rogid:agsPa0MUmIQXimutXTZgAGPbAwo6239	intact-crc:2F11DB486E4177D8|rigid:/BJq+YqtYh4wDYBQPKMIyKo5ypM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9C0D3	uniprotkb:Q15369	intact:EBI-1811414|uniprotkb:Q8N2X3|uniprotkb:Q9H8L8|ensembl:ENSP00000294353	intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9	psi-mi:zy11b_human(display_long)|uniprotkb:ZYG11B(gene name)|psi-mi:ZYG11B(display_short)|uniprotkb:KIAA1730(gene name synonym)	psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Vasudevan et al. (2007)	pubmed:17304241|imex:IM-11410|mint:MINT-5219657	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-1811411|imex:IM-11410-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078922.1|ensembl:ENSG00000162378(gene)|ensembl:ENST00000294353(transcript)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032675|interpro:IPR040367|mint:Q9C0D3	refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N	-	-	-	figure legend:Fig 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/03/26	2014/10/16	rogid:PL/P806AUcYTlvB6/2VS/UxLUYg9606	rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606	intact-crc:AA7AD1759FA3CCC8|rigid:WZAWX6og23neUx+XNSs3Df2C4aw	false	mutation disrupting interaction:18-18|mutation disrupting interaction:22-22	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7Z7L7	uniprotkb:Q15369	intact:EBI-1811449|uniprotkb:O00156|uniprotkb:Q5T272|uniprotkb:Q5T273|ensembl:ENSP00000291900	intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9	psi-mi:zer1_human(display_long)|uniprotkb:Zyg-11 homolog B-like protein(gene name synonym)|uniprotkb:Hzyg(gene name synonym)|uniprotkb:ZER1(gene name)|psi-mi:ZER1(display_short)|uniprotkb:C9orf60(gene name synonym)|uniprotkb:ZYG(gene name synonym)|uniprotkb:ZYG11BL(gene name synonym)|uniprotkb:Zyg11b-like protein(gene name synonym)	psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Vasudevan et al. (2007)	pubmed:17304241|imex:IM-11410|mint:MINT-5219657	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-1811438|imex:IM-11410-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006327.2|refseq:XP_011516424.1|refseq:XP_016869674.1|refseq:XP_005251702.1|ensembl:ENSG00000160445(gene)|ensembl:ENST00000291900(transcript)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032675|interpro:IPR040368|mint:Q7Z7L7	refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N	-	-	-	figure legend:Fig 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/03/26	2014/10/16	rogid:IWzURpjsw2cGVyaAkJhttRDlxzc9606	rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606	intact-crc:C854132630B93BFE|rigid:vDdt5dCZYH4MQ9eTeJftQcO0jqM	false	mutation disrupting interaction:9-9|mutation disrupting interaction:13-13	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q7Z7L7	uniprotkb:Q15370	intact:EBI-1811449|uniprotkb:O00156|uniprotkb:Q5T272|uniprotkb:Q5T273|ensembl:ENSP00000291900	intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3	psi-mi:zer1_human(display_long)|uniprotkb:Zyg-11 homolog B-like protein(gene name synonym)|uniprotkb:Hzyg(gene name synonym)|uniprotkb:ZER1(gene name)|psi-mi:ZER1(display_short)|uniprotkb:C9orf60(gene name synonym)|uniprotkb:ZYG(gene name synonym)|uniprotkb:ZYG11BL(gene name synonym)|uniprotkb:Zyg11b-like protein(gene name synonym)	psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Vasudevan et al. (2007)	pubmed:17304241|imex:IM-11410|mint:MINT-5219657	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-1811438|imex:IM-11410-10	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0684"(ancillary)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006327.2|refseq:XP_011516424.1|refseq:XP_016869674.1|refseq:XP_005251702.1|ensembl:ENSG00000160445(gene)|ensembl:ENST00000291900(transcript)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032675|interpro:IPR040368|mint:Q7Z7L7	ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N	-	-	-	figure legend:Fig 6A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/03/26	2014/10/16	rogid:IWzURpjsw2cGVyaAkJhttRDlxzc9606	rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606	intact-crc:C854132630B93BFE|rigid:vDdt5dCZYH4MQ9eTeJftQcO0jqM	false	mutation disrupting interaction:9-9|mutation disrupting interaction:13-13	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9C0D3	uniprotkb:Q13617	intact:EBI-1811414|uniprotkb:Q8N2X3|uniprotkb:Q9H8L8|ensembl:ENSP00000294353	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	psi-mi:zy11b_human(display_long)|uniprotkb:ZYG11B(gene name)|psi-mi:ZYG11B(display_short)|uniprotkb:KIAA1730(gene name synonym)	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Vasudevan et al. (2007)	pubmed:17304241|imex:IM-11410|mint:MINT-5219657	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-1811488|imex:IM-11410-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_078922.1|ensembl:ENSG00000162378(gene)|ensembl:ENST00000294353(transcript)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032675|interpro:IPR040367|mint:Q9C0D3	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	-	-	-	figure legend:Fig 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/03/26	2014/10/16	rogid:PL/P806AUcYTlvB6/2VS/UxLUYg9606	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	intact-crc:D3158205BD135E13|rigid:myUrP3AY8Y3BfDseYXSRfH+6+vM	false	vsv tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q7Z7L7	uniprotkb:Q13617	intact:EBI-1811449|uniprotkb:O00156|uniprotkb:Q5T272|uniprotkb:Q5T273|ensembl:ENSP00000291900	intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880	psi-mi:zer1_human(display_long)|uniprotkb:Zyg-11 homolog B-like protein(gene name synonym)|uniprotkb:Hzyg(gene name synonym)|uniprotkb:ZER1(gene name)|psi-mi:ZER1(display_short)|uniprotkb:C9orf60(gene name synonym)|uniprotkb:ZYG(gene name synonym)|uniprotkb:ZYG11BL(gene name synonym)|uniprotkb:Zyg11b-like protein(gene name synonym)	psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Vasudevan et al. (2007)	pubmed:17304241|imex:IM-11410|mint:MINT-5219657	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-1811494|imex:IM-11410-12	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006327.2|refseq:XP_011516424.1|refseq:XP_016869674.1|refseq:XP_005251702.1|ensembl:ENSG00000160445(gene)|ensembl:ENST00000291900(transcript)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR032675|interpro:IPR040368|mint:Q7Z7L7	refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553	-	-	-	figure legend:Fig 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/03/26	2014/10/16	rogid:IWzURpjsw2cGVyaAkJhttRDlxzc9606	rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606	intact-crc:8769E43D17978BE8|rigid:fKCbOwAxZr2S3RMCN60wuK6JbC8	false	vsv tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)