#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8WLQ7 uniprotkb:P06886 intact:EBI-7247555|intact:MINT-4328984 intact:EBI-7247529|intact:MINT-4328940 psi-mi:q8wlq7_human(display_long)|uniprotkb:HLA-DR4(gene name)|psi-mi:HLA-DR4(display_short) psi-mi:tsst_staau(display_long)|uniprotkb:tst(gene name)|psi-mi:tst(display_short) psi-mi:"MI:0107"(surface plasmon resonance) Moza et al. (2007) pubmed:17268555|imex:IM-11190|mint:MINT-5219593 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:1280(staau)|taxid:1280(Staphylococcus aureus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7247522|mint:MINT-4328977|imex:IM-11190-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q8WLQ7|interpro:IPR014745(MHC class II, alpha/beta chain, N-terminal)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|go:"GO:0006955"(immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0042613"(MHC class II protein complex)|interpro:IPR000353(MHC class II, beta chain, N-terminal)|mint:MINT-4328978(identity) mint:P06886|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR013307(Superantigen, bacterial)|go:"GO:0005576"(extracellular region)|go:"GO:0090729"(toxin activity)|rcsb pdb:1AW7|rcsb pdb:1QIL|rcsb pdb:1TS2|rcsb pdb:1TS3|rcsb pdb:1TS4|rcsb pdb:1TS5|rcsb pdb:2IJ0|rcsb pdb:2QIL|rcsb pdb:2TSS|rcsb pdb:3TSS|rcsb pdb:4OHJ|rcsb pdb:4TSS|rcsb pdb:5TSS|mint:MINT-4328980(identity) - comment:"fragmentation type: fragment"|comment:mint comment:mint|function:Responsible for the symptoms of toxic shock syndrome figure legend:F4A|kinetics:kd 1 micromolar|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/02 2014/10/16 rogid:wP8QqVlPatLizathIfoeGDL3KKU9606 rogid:gUTEEBSLOkleiFIZMFrkDj2DSEM1280 intact-crc:7EC3702C13BE9894|rigid:Rro7zrS3yYDSNHY4eR7Mir5ZlNU false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P06886 uniprotkb:P01733 intact:EBI-7247529|intact:MINT-4328940 intact:EBI-6165888|ensembl:ENSP00000477916|ensembl:ENSP00000487964|uniprotkb:A0A5A7|uniprotkb:A0A0A6YYD5 psi-mi:tsst_staau(display_long)|uniprotkb:tst(gene name)|psi-mi:tst(display_short) psi-mi:tvbl3_human(display_long)|uniprotkb:T-cell receptor beta chain V region YT35(gene name synonym)|uniprotkb:TCRBV12S3(gene name synonym)|uniprotkb:TRBV12-3(gene name)|psi-mi:TRBV12-3(display_short)|uniprotkb:TCRBV8S1(gene name synonym) psi-mi:"MI:0114"(x-ray crystallography) Moza et al. (2007) pubmed:17268555|imex:IM-11190|mint:MINT-5219593 taxid:1280(staau)|taxid:1280(Staphylococcus aureus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7247585|mint:MINT-4328965|imex:IM-11190-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:P06886|interpro:IPR008992(Enterotoxin, bacterial)|interpro:IPR006126(Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site)|interpro:IPR016091(Superantigen toxin, C-terminal, Staphylococcal/Streptococcal)|interpro:IPR013307(Superantigen, bacterial)|go:"GO:0005576"(extracellular region)|go:"GO:0090729"(toxin activity)|rcsb pdb:1AW7|rcsb pdb:1QIL|rcsb pdb:1TS2|rcsb pdb:1TS3|rcsb pdb:1TS4|rcsb pdb:1TS5|rcsb pdb:2IJ0|rcsb pdb:2QIL|rcsb pdb:2TSS|rcsb pdb:3TSS|rcsb pdb:4OHJ|rcsb pdb:4TSS|rcsb pdb:5TSS|mint:MINT-4328967(identity) reactome:R-HSA-202430|reactome:R-HSA-202433|reactome:R-HSA-389948|ensembl:ENSG00000274752(gene)|ensembl:ENSG00000282208(gene)|ensembl:ENST00000620569(transcript)|ensembl:ENST00000633292(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042287"(MHC protein binding)|go:"GO:0042605"(peptide antigen binding)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P01733|reactome:R-HSA-198933|reactome:R-HSA-202424|reactome:R-HSA-202427|mint:MINT-4328966(identity) - comment:mint|function:Responsible for the symptoms of toxic shock syndrome - figure legend:F2|figure legend:F1|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/03/02 2018/07/23 rogid:gUTEEBSLOkleiFIZMFrkDj2DSEM1280 rogid:Q1iF+Ih5FyVl9ty4wDJUaAVh/V89606 intact-crc:92294EA3D406E6A2|rigid:van2UUTb3S14BswOsmaHg7XJPcY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)