#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P97449 intact:EBI-1204817 intact:EBI-1183379|uniprotkb:Q91YH8|uniprotkb:Q99K63|ensembl:ENSMUSP00000035943|ensembl:ENSMUSP00000103015 - psi-mi:ampn_mouse(display_long)|uniprotkb:Anpep(gene name)|psi-mi:Anpep(display_short)|uniprotkb:Lap1(gene name synonym)|uniprotkb:Lap-1(gene name synonym)|uniprotkb:Alanyl aminopeptidase(gene name synonym)|uniprotkb:Microsomal aminopeptidase(gene name synonym)|uniprotkb:Aminopeptidase M(gene name synonym)|uniprotkb:Membrane protein p161(gene name synonym) psi-mi:pep_qfllgpaflvspvlep(display_short)|psi-mi:EBI-1204817(display_long) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183404|imex:IM-11844-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032512.2|refseq:XP_006540741.1|ensembl:ENSMUSG00000039062(gene)|ensembl:ENSMUST00000049004(transcript)|ensembl:ENSMUST00000107392(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|mint:P97449|reactome:R-MMU-6798695 refseq:XM_133071.4(primary-reference) psi-mi:"MI:0469"(intact) - no-uniprot-update:An amino acid sequence which is not represented in UniProt|caution:"The NCBI entry for this protein reads: This record was removed as a result of standard genome annotation processing. See the genome build documentation at http://www.ncbi.nlm.nih.gov/genome/guide/build.html for further information, or contact info@ncbi.nlm.nih.go"|comment:"The following motifs are present in the sequence: Glycosyl hydrolases family 31; pfam01055, P or trefoil or TFF domain; Trefoil factor family domain peptides are mucin-associated molecules, largely found in epithelia of gastrointestinal tissues; cd00111 (ncbi conserved domain database accession number)" figure legend:Table 1. Supporting Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:jC8fCyra4ze3wg0+0cCJ38HnVhk10090 rogid:6pF782ipqoEiIvkfJXsV0GiMX6010090 intact-crc:E608E2EF36670256|rigid:sEfFGVELywzNFKgGd14qH3HAZ/I false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P97449 intact:EBI-1205138 intact:EBI-1183379|uniprotkb:Q91YH8|uniprotkb:Q99K63|ensembl:ENSMUSP00000035943|ensembl:ENSMUSP00000103015 - psi-mi:ampn_mouse(display_long)|uniprotkb:Anpep(gene name)|psi-mi:Anpep(display_short)|uniprotkb:Lap1(gene name synonym)|uniprotkb:Lap-1(gene name synonym)|uniprotkb:Alanyl aminopeptidase(gene name synonym)|uniprotkb:Microsomal aminopeptidase(gene name synonym)|uniprotkb:Aminopeptidase M(gene name synonym)|uniprotkb:Membrane protein p161(gene name synonym) psi-mi:pep_ytllpfytlyfyr(display_short)|psi-mi:EBI-1205138(display_long) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183404|imex:IM-11844-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) refseq:NP_032512.2|refseq:XP_006540741.1|ensembl:ENSMUSG00000039062(gene)|ensembl:ENSMUST00000049004(transcript)|ensembl:ENSMUST00000107392(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|mint:P97449|reactome:R-MMU-6798695 - psi-mi:"MI:0469"(intact) - no-uniprot-update:An amino acid sequence which is not represented in UniProt figure legend:Table 1. Supporting Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:jC8fCyra4ze3wg0+0cCJ38HnVhk10090 rogid:AzFc4Fl2xJKsaBcGYFbVw59Zhv410090 intact-crc:E608E2EF36670256|rigid:sEfFGVELywzNFKgGd14qH3HAZ/I false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P97449 uniprotkb:Q8K0P6 intact:EBI-1183379|uniprotkb:Q91YH8|uniprotkb:Q99K63|ensembl:ENSMUSP00000035943|ensembl:ENSMUSP00000103015 intact:EBI-1183390 psi-mi:ampn_mouse(display_long)|uniprotkb:Anpep(gene name)|psi-mi:Anpep(display_short)|uniprotkb:Lap1(gene name synonym)|uniprotkb:Lap-1(gene name synonym)|uniprotkb:Alanyl aminopeptidase(gene name synonym)|uniprotkb:Microsomal aminopeptidase(gene name synonym)|uniprotkb:Aminopeptidase M(gene name synonym)|uniprotkb:Membrane protein p161(gene name synonym) psi-mi:q8k0p6_mouse(display_long)|uniprotkb:Fcgbp(gene name)|psi-mi:Fcgbp(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183404|imex:IM-11844-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032512.2|refseq:XP_006540741.1|ensembl:ENSMUSG00000039062(gene)|ensembl:ENSMUST00000049004(transcript)|ensembl:ENSMUST00000107392(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|mint:P97449|reactome:R-MMU-6798695 interpro:IPR036084|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR001007(von Willebrand factor, type C)|go:"GO:0005615"(extracellular space)|go:"GO:0031012"(extracellular matrix)|interpro:IPR025615 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supporting Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:jC8fCyra4ze3wg0+0cCJ38HnVhk10090 rogid:q+rWbyUAC2UcZr8tt5kE11i+iic10090 intact-crc:E608E2EF36670256|rigid:sEfFGVELywzNFKgGd14qH3HAZ/I false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P97449 uniprotkb:Q8VDN2 intact:EBI-1183379|uniprotkb:Q91YH8|uniprotkb:Q99K63|ensembl:ENSMUSP00000035943|ensembl:ENSMUSP00000103015 intact:EBI-444536|ensembl:ENSMUSP00000039657|uniprotkb:Q91Z09 psi-mi:ampn_mouse(display_long)|uniprotkb:Anpep(gene name)|psi-mi:Anpep(display_short)|uniprotkb:Lap1(gene name synonym)|uniprotkb:Lap-1(gene name synonym)|uniprotkb:Alanyl aminopeptidase(gene name synonym)|uniprotkb:Microsomal aminopeptidase(gene name synonym)|uniprotkb:Aminopeptidase M(gene name synonym)|uniprotkb:Membrane protein p161(gene name synonym) psi-mi:at1a1_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183457|imex:IM-11844-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032512.2|refseq:XP_006540741.1|ensembl:ENSMUSG00000039062(gene)|ensembl:ENSMUST00000049004(transcript)|ensembl:ENSMUST00000107392(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|mint:P97449|reactome:R-MMU-6798695 refseq:NP_659149.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q8VDN2|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000033161(gene)|ensembl:ENSMUST00000036493(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|dip:DIP-31885N psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supporting Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:jC8fCyra4ze3wg0+0cCJ38HnVhk10090 rogid:gz0ThqOMMsrl71IqGW0z8wbiqL410090 intact-crc:846D2899F46C0FF8|rigid:1gXQtDxCxgMfo+D4wUC6l+Rsnos false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P97449 uniprotkb:Q61847 intact:EBI-1183379|uniprotkb:Q91YH8|uniprotkb:Q99K63|ensembl:ENSMUSP00000035943|ensembl:ENSMUSP00000103015 intact:EBI-1183407|uniprotkb:Q059K0|ensembl:ENSMUSP00000080866 psi-mi:ampn_mouse(display_long)|uniprotkb:Anpep(gene name)|psi-mi:Anpep(display_short)|uniprotkb:Lap1(gene name synonym)|uniprotkb:Lap-1(gene name synonym)|uniprotkb:Alanyl aminopeptidase(gene name synonym)|uniprotkb:Microsomal aminopeptidase(gene name synonym)|uniprotkb:Aminopeptidase M(gene name synonym)|uniprotkb:Membrane protein p161(gene name synonym) psi-mi:mep1b_mouse(display_long)|uniprotkb:Mep1b(gene name)|psi-mi:Mep1b(display_short)|uniprotkb:Mep-1b(gene name synonym)|uniprotkb:Endopeptidase-2(gene name synonym)|uniprotkb:Meprin B(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183457|imex:IM-11844-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032512.2|refseq:XP_006540741.1|ensembl:ENSMUSG00000039062(gene)|ensembl:ENSMUST00000049004(transcript)|ensembl:ENSMUST00000107392(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|mint:P97449|reactome:R-MMU-6798695 refseq:NP_032612.2|ensembl:ENSMUSG00000024313(gene)|ensembl:ENSMUST00000082235(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0017090"(meprin A complex)|go:"GO:0042802"(identical protein binding)|go:"GO:1901998"(toxin transport)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000998(MAM)|interpro:IPR001506(Peptidase M12A, astacin)|interpro:IPR002083(MATH)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR008294(Peptidase M12A, meprin alpha subunit)|interpro:IPR008974(TRAF-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024079|interpro:IPR034302|mint:Q61847 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supporting Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:jC8fCyra4ze3wg0+0cCJ38HnVhk10090 rogid:+GiAtxXOKwSVUSX33XJ3do73/6c10090 intact-crc:846D2899F46C0FF8|rigid:1gXQtDxCxgMfo+D4wUC6l+Rsnos false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P97449 uniprotkb:Q7M758 intact:EBI-1183379|uniprotkb:Q91YH8|uniprotkb:Q99K63|ensembl:ENSMUSP00000035943|ensembl:ENSMUSP00000103015 intact:EBI-1183434|ensembl:ENSMUSP00000044231 psi-mi:ampn_mouse(display_long)|uniprotkb:Anpep(gene name)|psi-mi:Anpep(display_short)|uniprotkb:Lap1(gene name synonym)|uniprotkb:Lap-1(gene name synonym)|uniprotkb:Alanyl aminopeptidase(gene name synonym)|uniprotkb:Microsomal aminopeptidase(gene name synonym)|uniprotkb:Aminopeptidase M(gene name synonym)|uniprotkb:Membrane protein p161(gene name synonym) psi-mi:naldl_mouse(display_long)|uniprotkb:Naaladl1(gene name)|psi-mi:Naaladl1(display_short)|uniprotkb:Naaladasel(gene name synonym)|uniprotkb:Gm964(gene name synonym)|uniprotkb:N-acetylated-alpha-linked acidic dipeptidase-like protein(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183457|imex:IM-11844-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032512.2|refseq:XP_006540741.1|ensembl:ENSMUSG00000039062(gene)|ensembl:ENSMUST00000049004(transcript)|ensembl:ENSMUST00000107392(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|mint:P97449|reactome:R-MMU-6798695 refseq:NP_001009546.1|ensembl:ENSMUSG00000054999(gene)|ensembl:ENSMUST00000044451(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043171"(peptide catabolic process)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR036757|interpro:IPR039373 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supporting Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:jC8fCyra4ze3wg0+0cCJ38HnVhk10090 rogid:XaVDoRpwbssnL3SZkMrkdQdH4cM10090 intact-crc:846D2899F46C0FF8|rigid:1gXQtDxCxgMfo+D4wUC6l+Rsnos false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P97449 uniprotkb:Q52JJ6 intact:EBI-1183379|uniprotkb:Q91YH8|uniprotkb:Q99K63|ensembl:ENSMUSP00000035943|ensembl:ENSMUSP00000103015 intact:EBI-1183443 psi-mi:ampn_mouse(display_long)|uniprotkb:Anpep(gene name)|psi-mi:Anpep(display_short)|uniprotkb:Lap1(gene name synonym)|uniprotkb:Lap-1(gene name synonym)|uniprotkb:Alanyl aminopeptidase(gene name synonym)|uniprotkb:Microsomal aminopeptidase(gene name synonym)|uniprotkb:Aminopeptidase M(gene name synonym)|uniprotkb:Membrane protein p161(gene name synonym) psi-mi:q52jj6_mouse(display_long)|uniprotkb:Enpep(gene name)|psi-mi:Enpep(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183457|imex:IM-11844-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032512.2|refseq:XP_006540741.1|ensembl:ENSMUSG00000039062(gene)|ensembl:ENSMUST00000049004(transcript)|ensembl:ENSMUST00000107392(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|mint:P97449|reactome:R-MMU-6798695 refseq:NP_031960.1|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR033508|go:"GO:0003081"(regulation of systemic arterial blood pressure by renin-angiotensin)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0070006"(metalloaminopeptidase activity)|interpro:IPR024571|interpro:IPR034016|interpro:IPR027268|interpro:IPR042097 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supporting Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:jC8fCyra4ze3wg0+0cCJ38HnVhk10090 rogid:bDro3Qmjuqod515sHYhg69YNhmA10090 intact-crc:846D2899F46C0FF8|rigid:1gXQtDxCxgMfo+D4wUC6l+Rsnos false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P97449 uniprotkb:Q8K0P6 intact:EBI-1183379|uniprotkb:Q91YH8|uniprotkb:Q99K63|ensembl:ENSMUSP00000035943|ensembl:ENSMUSP00000103015 intact:EBI-1183390 psi-mi:ampn_mouse(display_long)|uniprotkb:Anpep(gene name)|psi-mi:Anpep(display_short)|uniprotkb:Lap1(gene name synonym)|uniprotkb:Lap-1(gene name synonym)|uniprotkb:Alanyl aminopeptidase(gene name synonym)|uniprotkb:Microsomal aminopeptidase(gene name synonym)|uniprotkb:Aminopeptidase M(gene name synonym)|uniprotkb:Membrane protein p161(gene name synonym) psi-mi:q8k0p6_mouse(display_long)|uniprotkb:Fcgbp(gene name)|psi-mi:Fcgbp(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183457|imex:IM-11844-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032512.2|refseq:XP_006540741.1|ensembl:ENSMUSG00000039062(gene)|ensembl:ENSMUST00000049004(transcript)|ensembl:ENSMUST00000107392(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|mint:P97449|reactome:R-MMU-6798695 interpro:IPR036084|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR001007(von Willebrand factor, type C)|go:"GO:0005615"(extracellular space)|go:"GO:0031012"(extracellular matrix)|interpro:IPR025615 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supporting Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:jC8fCyra4ze3wg0+0cCJ38HnVhk10090 rogid:q+rWbyUAC2UcZr8tt5kE11i+iic10090 intact-crc:846D2899F46C0FF8|rigid:1gXQtDxCxgMfo+D4wUC6l+Rsnos false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P97449 uniprotkb:P14094 intact:EBI-1183379|uniprotkb:Q91YH8|uniprotkb:Q99K63|ensembl:ENSMUSP00000035943|ensembl:ENSMUSP00000103015 intact:EBI-770851|ensembl:ENSMUSP00000027863 psi-mi:ampn_mouse(display_long)|uniprotkb:Anpep(gene name)|psi-mi:Anpep(display_short)|uniprotkb:Lap1(gene name synonym)|uniprotkb:Lap-1(gene name synonym)|uniprotkb:Alanyl aminopeptidase(gene name synonym)|uniprotkb:Microsomal aminopeptidase(gene name synonym)|uniprotkb:Aminopeptidase M(gene name synonym)|uniprotkb:Membrane protein p161(gene name synonym) psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183478|imex:IM-11844-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032512.2|refseq:XP_006540741.1|ensembl:ENSMUSG00000039062(gene)|ensembl:ENSMUST00000049004(transcript)|ensembl:ENSMUST00000107392(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|mint:P97449|reactome:R-MMU-6798695 refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supporting Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:jC8fCyra4ze3wg0+0cCJ38HnVhk10090 rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090 intact-crc:CF8D2584E2CD91A9|rigid:GAo4vHhq+737OJw3SvdOcMhdo3g false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P97449 uniprotkb:Q8K0P6 intact:EBI-1183379|uniprotkb:Q91YH8|uniprotkb:Q99K63|ensembl:ENSMUSP00000035943|ensembl:ENSMUSP00000103015 intact:EBI-1183390 psi-mi:ampn_mouse(display_long)|uniprotkb:Anpep(gene name)|psi-mi:Anpep(display_short)|uniprotkb:Lap1(gene name synonym)|uniprotkb:Lap-1(gene name synonym)|uniprotkb:Alanyl aminopeptidase(gene name synonym)|uniprotkb:Microsomal aminopeptidase(gene name synonym)|uniprotkb:Aminopeptidase M(gene name synonym)|uniprotkb:Membrane protein p161(gene name synonym) psi-mi:q8k0p6_mouse(display_long)|uniprotkb:Fcgbp(gene name)|psi-mi:Fcgbp(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183478|imex:IM-11844-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032512.2|refseq:XP_006540741.1|ensembl:ENSMUSG00000039062(gene)|ensembl:ENSMUST00000049004(transcript)|ensembl:ENSMUST00000107392(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|mint:P97449|reactome:R-MMU-6798695 interpro:IPR036084|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR001007(von Willebrand factor, type C)|go:"GO:0005615"(extracellular space)|go:"GO:0031012"(extracellular matrix)|interpro:IPR025615 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supporting Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:jC8fCyra4ze3wg0+0cCJ38HnVhk10090 rogid:q+rWbyUAC2UcZr8tt5kE11i+iic10090 intact-crc:CF8D2584E2CD91A9|rigid:GAo4vHhq+737OJw3SvdOcMhdo3g false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P97449 uniprotkb:Q01853 intact:EBI-1183379|uniprotkb:Q91YH8|uniprotkb:Q99K63|ensembl:ENSMUSP00000035943|ensembl:ENSMUSP00000103015 intact:EBI-80597|ensembl:ENSMUSP00000030164|uniprotkb:Q3TFH9|uniprotkb:Q3TIM2|uniprotkb:Q3TXN9|uniprotkb:Q6PI18|uniprotkb:Q8BSR6|uniprotkb:Q8CEG4 psi-mi:ampn_mouse(display_long)|uniprotkb:Anpep(gene name)|psi-mi:Anpep(display_short)|uniprotkb:Lap1(gene name synonym)|uniprotkb:Lap-1(gene name synonym)|uniprotkb:Alanyl aminopeptidase(gene name synonym)|uniprotkb:Microsomal aminopeptidase(gene name synonym)|uniprotkb:Aminopeptidase M(gene name synonym)|uniprotkb:Membrane protein p161(gene name synonym) psi-mi:tera_mouse(display_long)|uniprotkb:Vcp(gene name)|psi-mi:Vcp(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183478|imex:IM-11844-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032512.2|refseq:XP_006540741.1|ensembl:ENSMUSG00000039062(gene)|ensembl:ENSMUST00000049004(transcript)|ensembl:ENSMUST00000107392(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|mint:P97449|reactome:R-MMU-6798695 go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:Q01853|rcsb pdb:1E32|rcsb pdb:1R7R|rcsb pdb:1S3S|rcsb pdb:2PJH|rcsb pdb:3CF0|rcsb pdb:3CF1|rcsb pdb:3CF2|rcsb pdb:3CF3|reactome:R-MMU-110320|reactome:R-MMU-3371511|reactome:R-MMU-382556|reactome:R-MMU-532668|reactome:R-MMU-5358346|reactome:R-MMU-5689877|reactome:R-MMU-5689896|reactome:R-MMU-6798695|reactome:R-MMU-8876725|reactome:R-MMU-9013407|ensembl:ENSMUSG00000028452(gene)|ensembl:ENSMUST00000030164(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0019904"(protein domain specific binding)|refseq:NP_033529.3|dip:DIP-29796N psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supporting Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:jC8fCyra4ze3wg0+0cCJ38HnVhk10090 rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs10090 intact-crc:CF8D2584E2CD91A9|rigid:GAo4vHhq+737OJw3SvdOcMhdo3g false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q8VDN2 uniprotkb:P14094 intact:EBI-444536|ensembl:ENSMUSP00000039657|uniprotkb:Q91Z09 intact:EBI-770851|ensembl:ENSMUSP00000027863 psi-mi:at1a1_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short) psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183526|imex:IM-11844-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_659149.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q8VDN2|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000033161(gene)|ensembl:ENSMUST00000036493(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|dip:DIP-31885N refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:gz0ThqOMMsrl71IqGW0z8wbiqL410090 rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090 intact-crc:CC3391A60466D8F9|rigid:Vqp/jh+UIy9htgTg3IHru/LXS58 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q8VDN2 uniprotkb:Q99JW5 intact:EBI-444536|ensembl:ENSMUSP00000039657|uniprotkb:Q91Z09 intact:EBI-1183486|uniprotkb:Q61512|ensembl:ENSMUSP00000061935|ensembl:ENSMUSP00000157040 psi-mi:at1a1_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short) psi-mi:epcam_mouse(display_long)|uniprotkb:Epcam(gene name)|psi-mi:Epcam(display_short)|uniprotkb:Tacstd1(gene name synonym)|uniprotkb:Epithelial glycoprotein 314(gene name synonym)|uniprotkb:Protein 289A(gene name synonym)|uniprotkb:Tumor-associated calcium signal transducer 1(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183526|imex:IM-11844-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_659149.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q8VDN2|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000033161(gene)|ensembl:ENSMUST00000036493(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|dip:DIP-31885N refseq:NP_032558.2|ensembl:ENSMUSG00000045394(gene)|ensembl:ENSMUST00000053577(transcript)|ensembl:ENSMUST00000234623(transcript)|go:"GO:0001657"(ureteric bud development)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR036857|interpro:IPR041630|interpro:IPR043406|reactome:R-MMU-202733 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:gz0ThqOMMsrl71IqGW0z8wbiqL410090 rogid:5qI9V80qfSE6vKkckQ82klN56iY10090 intact-crc:CC3391A60466D8F9|rigid:Vqp/jh+UIy9htgTg3IHru/LXS58 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q8VDN2 uniprotkb:Q5XLR9 intact:EBI-444536|ensembl:ENSMUSP00000039657|uniprotkb:Q91Z09 intact:EBI-1204986 psi-mi:at1a1_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short) psi-mi:q5xlr9_mouse(display_long)|uniprotkb:Lct(gene name)|psi-mi:Lct(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183526|imex:IM-11844-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_659149.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q8VDN2|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000033161(gene)|ensembl:ENSMUST00000036493(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|dip:DIP-31885N interpro:IPR001360(Glycoside hydrolase, family 1)|interpro:IPR018120|interpro:IPR017853(Glycoside hydrolase, catalytic core)|go:"GO:0000016"(lactase activity)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005903"(brush border)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008422"(beta-glucosidase activity)|go:"GO:0010033"(response to organic substance)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010045"(response to nickel cation)|go:"GO:0010288"(response to lead ion)|go:"GO:0016740"(transferase activity)|go:"GO:0042493"|go:"GO:0045471"(response to ethanol)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:gz0ThqOMMsrl71IqGW0z8wbiqL410090 rogid:PIXJgmpkUOtVuWxpmlSOTLK5PVc10090 intact-crc:CC3391A60466D8F9|rigid:Vqp/jh+UIy9htgTg3IHru/LXS58 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q8VDN2 uniprotkb:Q8C3K6 intact:EBI-444536|ensembl:ENSMUSP00000039657|uniprotkb:Q91Z09 intact:EBI-1183514 psi-mi:at1a1_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short) psi-mi:sc5a1_mouse(display_long)|uniprotkb:Slc5a1(gene name)|psi-mi:Slc5a1(display_short)|uniprotkb:High affinity sodium-glucose cotransporter(gene name synonym)|uniprotkb:Solute carrier family 5 member 1(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183526|imex:IM-11844-4 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_659149.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q8VDN2|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000033161(gene)|ensembl:ENSMUST00000036493(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|dip:DIP-31885N refseq:NP_062784.3|interpro:IPR001734(Na+/solute symporter)|interpro:IPR018212|interpro:IPR038377|go:"GO:0000017"(alpha-glucoside transport)|go:"GO:0001656"(metanephros development)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005372"(water transmembrane transporter activity)|go:"GO:0005412"("glucose:sodium symporter activity")|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006814"(sodium ion transport)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0015151"(alpha-glucoside transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0043229"(intracellular organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050892"(intestinal absorption)|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0098708"(glucose import across plasma membrane)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904659"(glucose transmembrane transport)|reactome:R-MMU-189200|reactome:R-MMU-8981373 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:gz0ThqOMMsrl71IqGW0z8wbiqL410090 rogid:gZxjteCXMWVvMWNPPPLp0Gpp7ZI10090 intact-crc:CC3391A60466D8F9|rigid:Vqp/jh+UIy9htgTg3IHru/LXS58 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q99JY9 uniprotkb:Q8VDN2 intact:EBI-773994|uniprotkb:Q9DC56|ensembl:ENSMUSP00000027579|ensembl:ENSMUSP00000137503 intact:EBI-444536|ensembl:ENSMUSP00000039657|uniprotkb:Q91Z09 psi-mi:arp3_mouse(display_long)|uniprotkb:Actin-like protein 3(gene name synonym)|uniprotkb:Actr3(gene name)|psi-mi:Actr3(display_short)|uniprotkb:Arp3(gene name synonym) psi-mi:at1a1_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183575|imex:IM-11844-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001192314.1|refseq:NP_001192315.1|refseq:NP_076224.1|ensembl:ENSMUSG00000026341(gene)|ensembl:ENSMUST00000027579(transcript)|ensembl:ENSMUST00000178474(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0030027"(lamellipodium)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060271"(cilium assembly)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061825"(podosome core)|go:"GO:0061828"(apical tubulobulbar complex)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0061832"(basal ectoplasmic specialization)|go:"GO:0061851"(leading edge of lamellipodium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904171"(negative regulation of bleb assembly)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR015623(Actin-related protein 3)|interpro:IPR020902|interpro:IPR043129|mint:Q99JY9|rcsb pdb:7AQK|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-5663213|reactome:R-MMU-8856828 refseq:NP_659149.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q8VDN2|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000033161(gene)|ensembl:ENSMUST00000036493(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|dip:DIP-31885N psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:FBCctn7WChHon0MhVlJUO4ctinE10090 rogid:gz0ThqOMMsrl71IqGW0z8wbiqL410090 intact-crc:D61FBCA13407609A|rigid:goGnZayifMQvC+Q6HmopaYwPeXM false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q99JY9 uniprotkb:P14094 intact:EBI-773994|uniprotkb:Q9DC56|ensembl:ENSMUSP00000027579|ensembl:ENSMUSP00000137503 intact:EBI-770851|ensembl:ENSMUSP00000027863 psi-mi:arp3_mouse(display_long)|uniprotkb:Actin-like protein 3(gene name synonym)|uniprotkb:Actr3(gene name)|psi-mi:Actr3(display_short)|uniprotkb:Arp3(gene name synonym) psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183575|imex:IM-11844-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001192314.1|refseq:NP_001192315.1|refseq:NP_076224.1|ensembl:ENSMUSG00000026341(gene)|ensembl:ENSMUST00000027579(transcript)|ensembl:ENSMUST00000178474(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0030027"(lamellipodium)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060271"(cilium assembly)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061825"(podosome core)|go:"GO:0061828"(apical tubulobulbar complex)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0061832"(basal ectoplasmic specialization)|go:"GO:0061851"(leading edge of lamellipodium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904171"(negative regulation of bleb assembly)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR015623(Actin-related protein 3)|interpro:IPR020902|interpro:IPR043129|mint:Q99JY9|rcsb pdb:7AQK|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-5663213|reactome:R-MMU-8856828 refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:FBCctn7WChHon0MhVlJUO4ctinE10090 rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090 intact-crc:D61FBCA13407609A|rigid:goGnZayifMQvC+Q6HmopaYwPeXM false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q99JY9 uniprotkb:Q99JW5 intact:EBI-773994|uniprotkb:Q9DC56|ensembl:ENSMUSP00000027579|ensembl:ENSMUSP00000137503 intact:EBI-1183486|uniprotkb:Q61512|ensembl:ENSMUSP00000061935|ensembl:ENSMUSP00000157040 psi-mi:arp3_mouse(display_long)|uniprotkb:Actin-like protein 3(gene name synonym)|uniprotkb:Actr3(gene name)|psi-mi:Actr3(display_short)|uniprotkb:Arp3(gene name synonym) psi-mi:epcam_mouse(display_long)|uniprotkb:Epcam(gene name)|psi-mi:Epcam(display_short)|uniprotkb:Tacstd1(gene name synonym)|uniprotkb:Epithelial glycoprotein 314(gene name synonym)|uniprotkb:Protein 289A(gene name synonym)|uniprotkb:Tumor-associated calcium signal transducer 1(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183575|imex:IM-11844-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001192314.1|refseq:NP_001192315.1|refseq:NP_076224.1|ensembl:ENSMUSG00000026341(gene)|ensembl:ENSMUST00000027579(transcript)|ensembl:ENSMUST00000178474(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0030027"(lamellipodium)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060271"(cilium assembly)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061825"(podosome core)|go:"GO:0061828"(apical tubulobulbar complex)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0061832"(basal ectoplasmic specialization)|go:"GO:0061851"(leading edge of lamellipodium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904171"(negative regulation of bleb assembly)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR015623(Actin-related protein 3)|interpro:IPR020902|interpro:IPR043129|mint:Q99JY9|rcsb pdb:7AQK|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-5663213|reactome:R-MMU-8856828 refseq:NP_032558.2|ensembl:ENSMUSG00000045394(gene)|ensembl:ENSMUST00000053577(transcript)|ensembl:ENSMUST00000234623(transcript)|go:"GO:0001657"(ureteric bud development)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR036857|interpro:IPR041630|interpro:IPR043406|reactome:R-MMU-202733 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:FBCctn7WChHon0MhVlJUO4ctinE10090 rogid:5qI9V80qfSE6vKkckQ82klN56iY10090 intact-crc:D61FBCA13407609A|rigid:goGnZayifMQvC+Q6HmopaYwPeXM false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q99JY9 uniprotkb:Q9JIP7 intact:EBI-773994|uniprotkb:Q9DC56|ensembl:ENSMUSP00000027579|ensembl:ENSMUSP00000137503 intact:EBI-1183563|uniprotkb:E9QMX3|ensembl:ENSMUSP00000085728 psi-mi:arp3_mouse(display_long)|uniprotkb:Actin-like protein 3(gene name synonym)|uniprotkb:Actr3(gene name)|psi-mi:Actr3(display_short)|uniprotkb:Arp3(gene name synonym) psi-mi:s15a1_mouse(display_long)|uniprotkb:Peptide transporter 1(gene name synonym)|uniprotkb:Oligopeptide transporter, small intestine isoform(gene name synonym)|uniprotkb:"Intestinal H(+)/peptide cotransporter"(gene name synonym)|uniprotkb:Proton-coupled dipeptide cotransporter(gene name synonym)|uniprotkb:Slc15a1(gene name)|psi-mi:Slc15a1(display_short)|uniprotkb:Pept1(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183575|imex:IM-11844-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001192314.1|refseq:NP_001192315.1|refseq:NP_076224.1|ensembl:ENSMUSG00000026341(gene)|ensembl:ENSMUST00000027579(transcript)|ensembl:ENSMUST00000178474(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0030027"(lamellipodium)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060271"(cilium assembly)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061825"(podosome core)|go:"GO:0061828"(apical tubulobulbar complex)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0061832"(basal ectoplasmic specialization)|go:"GO:0061851"(leading edge of lamellipodium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904171"(negative regulation of bleb assembly)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR015623(Actin-related protein 3)|interpro:IPR020902|interpro:IPR043129|mint:Q99JY9|rcsb pdb:7AQK|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-5663213|reactome:R-MMU-8856828 refseq:NP_444309.2|ensembl:ENSMUSG00000025557(gene)|ensembl:ENSMUST00000088386(transcript)|go:"GO:0005427"(proton-dependent oligopeptide secondary active transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006857"(oligopeptide transport)|go:"GO:0015031"(protein transport)|go:"GO:0015333"("peptide:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016248"(channel inhibitor activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0051956"(negative regulation of amino acid transport)|go:"GO:0071916"(dipeptide transmembrane transporter activity)|go:"GO:0140206"(dipeptide import across plasma membrane)|interpro:IPR000109(TGF-beta receptor, type I/II extracellular region)|interpro:IPR004768("Oligopeptide transporter, peptide:H+ symporter")|interpro:IPR018456|interpro:IPR036259|rcsb pdb:5A9D|reactome:R-MMU-427975 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:FBCctn7WChHon0MhVlJUO4ctinE10090 rogid:+cfDFNvyaWsju6sLUz5yQbcN6Dk10090 intact-crc:D61FBCA13407609A|rigid:goGnZayifMQvC+Q6HmopaYwPeXM false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:Q8VDN2 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-444536|ensembl:ENSMUSP00000039657|uniprotkb:Q91Z09 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:at1a1_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183592|imex:IM-11844-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 refseq:NP_659149.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q8VDN2|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000033161(gene)|ensembl:ENSMUST00000036493(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|dip:DIP-31885N psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:gz0ThqOMMsrl71IqGW0z8wbiqL410090 intact-crc:E85D60B06C5B1D6D|rigid:iyQEeULIBn5ocpQnRNpMbpJ3Pwk false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:Q99JW5 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-1183486|uniprotkb:Q61512|ensembl:ENSMUSP00000061935|ensembl:ENSMUSP00000157040 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:epcam_mouse(display_long)|uniprotkb:Epcam(gene name)|psi-mi:Epcam(display_short)|uniprotkb:Tacstd1(gene name synonym)|uniprotkb:Epithelial glycoprotein 314(gene name synonym)|uniprotkb:Protein 289A(gene name synonym)|uniprotkb:Tumor-associated calcium signal transducer 1(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183592|imex:IM-11844-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 refseq:NP_032558.2|ensembl:ENSMUSG00000045394(gene)|ensembl:ENSMUST00000053577(transcript)|ensembl:ENSMUST00000234623(transcript)|go:"GO:0001657"(ureteric bud development)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR036857|interpro:IPR041630|interpro:IPR043406|reactome:R-MMU-202733 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:5qI9V80qfSE6vKkckQ82klN56iY10090 intact-crc:E85D60B06C5B1D6D|rigid:iyQEeULIBn5ocpQnRNpMbpJ3Pwk false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:Q8R3G9 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-1183583|ensembl:ENSMUSP00000049243|ensembl:ENSMUSP00000079463|ensembl:ENSMUSP00000136645 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:tsn8_mouse(display_long)|uniprotkb:Tspan8(gene name)|psi-mi:Tspan8(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183592|imex:IM-11844-6 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 refseq:NP_001162150.1|refseq:NP_001162151.1|refseq:NP_666122.1|refseq:XP_006513605.1|ensembl:ENSMUSG00000034127(gene)|ensembl:ENSMUST00000035563(transcript)|ensembl:ENSMUST00000080630(transcript)|ensembl:ENSMUST00000179196(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030195"(negative regulation of blood coagulation)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:gW56LLxU6qV0B2XF5OV1Ki4mwj410090 intact-crc:E85D60B06C5B1D6D|rigid:iyQEeULIBn5ocpQnRNpMbpJ3Pwk false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P57780 uniprotkb:O08601 intact:EBI-445071|ensembl:ENSMUSP00000066068 intact:EBI-1183611|uniprotkb:B2CXA7|uniprotkb:Q3UJA0|uniprotkb:Q91X33|ensembl:ENSMUSP00000029805 psi-mi:actn4_mouse(display_long)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym)|uniprotkb:Actn4(gene name)|psi-mi:Actn4(display_short) psi-mi:mtp_mouse(display_long)|uniprotkb:Mttp(gene name)|psi-mi:Mttp(display_short)|uniprotkb:Mtp(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183624|imex:IM-11844-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068695.1|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P57780|reactome:R-MMU-114608|ensembl:ENSMUSG00000054808(gene)|ensembl:ENSMUST00000068045(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001725"(stress fiber)|go:"GO:0001882"(nucleoside binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030018"(Z disc)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031143"(pseudopodium)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902396"(protein localization to bicellular tight junction) refseq:NP_001156929.1|refseq:NP_032668.2|ensembl:ENSMUSG00000028158(gene)|ensembl:ENSMUST00000029805(transcript)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006497"(protein lipidation)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009306"(protein secretion)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034197"(triglyceride transport)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034377"(plasma lipoprotein particle assembly)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0006629"(lipid metabolic process)|refseq:XP_006501165.1|refseq:XP_006501166.1|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051592"(response to calcium ion)|go:"GO:0120014"(phospholipid transfer activity)|go:"GO:0120019"(phosphatidylcholine transfer activity)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:0140344"(triglyceride transfer activity)|go:"GO:1902388"(ceramide 1-phosphate transfer activity)|go:"GO:1904121"(phosphatidylethanolamine transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR039988|mint:O08601|go:"GO:0042953"(lipoprotein transport)|reactome:R-MMU-8963888|reactome:R-MMU-8866423|refseq:XP_017174963.1|refseq:XP_017174964.1 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:IeHeXy0Cx5E6ivN3b8IxESBlhJI10090 rogid:7VKaqT/iEzsvkw6SA1aX3ef2sgA10090 intact-crc:2C1731D002F438D7|rigid:uRMeaQza363vblh26ho1eJtuY7M false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P57780 uniprotkb:P09103 intact:EBI-445071|ensembl:ENSMUSP00000066068 intact:EBI-494709|uniprotkb:Q922C8|ensembl:ENSMUSP00000026122 psi-mi:actn4_mouse(display_long)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym)|uniprotkb:Actn4(gene name)|psi-mi:Actn4(display_short) psi-mi:pdia1_mouse(display_long)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 59(gene name synonym)|uniprotkb:P4hb(gene name)|psi-mi:P4hb(display_short)|uniprotkb:Pdia1(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183624|imex:IM-11844-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068695.1|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P57780|reactome:R-MMU-114608|ensembl:ENSMUSG00000054808(gene)|ensembl:ENSMUST00000068045(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001725"(stress fiber)|go:"GO:0001882"(nucleoside binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030018"(Z disc)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031143"(pseudopodium)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902396"(protein localization to bicellular tight junction) refseq:NP_035162.1|ensembl:ENSMUSG00000025130(gene)|ensembl:ENSMUST00000026122(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P09103|reactome:R-MMU-1650814|reactome:R-MMU-3299685|reactome:R-MMU-381426|reactome:R-MMU-5358346|reactome:R-MMU-8866423|reactome:R-MMU-8957275|reactome:R-MMU-8963888|reactome:R-MMU-9020591|reactome:R-MMU-9020933 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:IeHeXy0Cx5E6ivN3b8IxESBlhJI10090 rogid:j20LBPF1r9AYUdJAgzNS/+Uq8GY10090 intact-crc:2C1731D002F438D7|rigid:uRMeaQza363vblh26ho1eJtuY7M false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P57780 uniprotkb:Q62468 intact:EBI-445071|ensembl:ENSMUSP00000066068 intact:EBI-1183601|uniprotkb:Q149B6|uniprotkb:Q91WH4|ensembl:ENSMUSP00000027366 psi-mi:actn4_mouse(display_long)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym)|uniprotkb:Actn4(gene name)|psi-mi:Actn4(display_short) psi-mi:vili_mouse(display_long)|uniprotkb:Vil1(gene name)|psi-mi:Vil1(display_short)|uniprotkb:Vil(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183624|imex:IM-11844-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_068695.1|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P57780|reactome:R-MMU-114608|ensembl:ENSMUSG00000054808(gene)|ensembl:ENSMUST00000068045(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001725"(stress fiber)|go:"GO:0001882"(nucleoside binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030018"(Z disc)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031143"(pseudopodium)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902396"(protein localization to bicellular tight junction) refseq:NP_033535.2|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|mint:Q62468|go:"GO:1902896"(terminal web assembly)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0032532"(regulation of microvillus length)|ensembl:ENSMUSG00000026175(gene)|ensembl:ENSMUST00000027366(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:IeHeXy0Cx5E6ivN3b8IxESBlhJI10090 rogid:0+lYMSTWQyTkDecT6ZQgeXblR4Y10090 intact-crc:2C1731D002F438D7|rigid:uRMeaQza363vblh26ho1eJtuY7M false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:O08601 uniprotkb:P09103 intact:EBI-1183611|uniprotkb:B2CXA7|uniprotkb:Q3UJA0|uniprotkb:Q91X33|ensembl:ENSMUSP00000029805 intact:EBI-494709|uniprotkb:Q922C8|ensembl:ENSMUSP00000026122 psi-mi:mtp_mouse(display_long)|uniprotkb:Mttp(gene name)|psi-mi:Mttp(display_short)|uniprotkb:Mtp(gene name synonym) psi-mi:pdia1_mouse(display_long)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 59(gene name synonym)|uniprotkb:P4hb(gene name)|psi-mi:P4hb(display_short)|uniprotkb:Pdia1(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183644|imex:IM-11844-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001156929.1|refseq:NP_032668.2|ensembl:ENSMUSG00000028158(gene)|ensembl:ENSMUST00000029805(transcript)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006497"(protein lipidation)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009306"(protein secretion)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034197"(triglyceride transport)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034377"(plasma lipoprotein particle assembly)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0006629"(lipid metabolic process)|refseq:XP_006501165.1|refseq:XP_006501166.1|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051592"(response to calcium ion)|go:"GO:0120014"(phospholipid transfer activity)|go:"GO:0120019"(phosphatidylcholine transfer activity)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:0140344"(triglyceride transfer activity)|go:"GO:1902388"(ceramide 1-phosphate transfer activity)|go:"GO:1904121"(phosphatidylethanolamine transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR039988|mint:O08601|go:"GO:0042953"(lipoprotein transport)|reactome:R-MMU-8963888|reactome:R-MMU-8866423|refseq:XP_017174963.1|refseq:XP_017174964.1 refseq:NP_035162.1|ensembl:ENSMUSG00000025130(gene)|ensembl:ENSMUST00000026122(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P09103|reactome:R-MMU-1650814|reactome:R-MMU-3299685|reactome:R-MMU-381426|reactome:R-MMU-5358346|reactome:R-MMU-8866423|reactome:R-MMU-8957275|reactome:R-MMU-8963888|reactome:R-MMU-9020591|reactome:R-MMU-9020933 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:7VKaqT/iEzsvkw6SA1aX3ef2sgA10090 rogid:j20LBPF1r9AYUdJAgzNS/+Uq8GY10090 intact-crc:EF55CB7CED858C3E|rigid:HTCHXt3MFMeYOnL1n9ZC/zWce8M false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:O08601 uniprotkb:Q9D687 intact:EBI-1183611|uniprotkb:B2CXA7|uniprotkb:Q3UJA0|uniprotkb:Q91X33|ensembl:ENSMUSP00000029805 intact:EBI-1183633|ensembl:ENSMUSP00000022048 psi-mi:mtp_mouse(display_long)|uniprotkb:Mttp(gene name)|psi-mi:Mttp(display_short)|uniprotkb:Mtp(gene name synonym) psi-mi:s6a19_mouse(display_long)|uniprotkb:"System B(0) neutral amino acid transporter AT1"(gene name synonym)|uniprotkb:Solute carrier family 6 member 19(gene name synonym)|uniprotkb:Slc6a19(gene name)|psi-mi:Slc6a19(display_short)|uniprotkb:B0at1(gene name synonym)|uniprotkb:Xt3(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183644|imex:IM-11844-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001156929.1|refseq:NP_032668.2|ensembl:ENSMUSG00000028158(gene)|ensembl:ENSMUST00000029805(transcript)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006497"(protein lipidation)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009306"(protein secretion)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034197"(triglyceride transport)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034377"(plasma lipoprotein particle assembly)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0006629"(lipid metabolic process)|refseq:XP_006501165.1|refseq:XP_006501166.1|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051592"(response to calcium ion)|go:"GO:0120014"(phospholipid transfer activity)|go:"GO:0120019"(phosphatidylcholine transfer activity)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:0140344"(triglyceride transfer activity)|go:"GO:1902388"(ceramide 1-phosphate transfer activity)|go:"GO:1904121"(phosphatidylethanolamine transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR039988|mint:O08601|go:"GO:0042953"(lipoprotein transport)|reactome:R-MMU-8963888|reactome:R-MMU-8866423|refseq:XP_017174963.1|refseq:XP_017174964.1 refseq:NP_083154.1|mint:Q9D687|reactome:R-MMU-352230|reactome:R-MMU-442660|interpro:IPR037272|ensembl:ENSMUSG00000021565(gene)|ensembl:ENSMUST00000022048(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007584"(response to nutrient)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015804"(neutral amino acid transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0035725"(sodium ion transmembrane transport)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002438("Sodium:neurotransmitter symporter, orphan")|dip:DIP-38102N psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:7VKaqT/iEzsvkw6SA1aX3ef2sgA10090 rogid:ElkMXioLvCipJK9tRd2M0dM3JMs10090 intact-crc:EF55CB7CED858C3E|rigid:HTCHXt3MFMeYOnL1n9ZC/zWce8M false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:O08601 uniprotkb:Q62468 intact:EBI-1183611|uniprotkb:B2CXA7|uniprotkb:Q3UJA0|uniprotkb:Q91X33|ensembl:ENSMUSP00000029805 intact:EBI-1183601|uniprotkb:Q149B6|uniprotkb:Q91WH4|ensembl:ENSMUSP00000027366 psi-mi:mtp_mouse(display_long)|uniprotkb:Mttp(gene name)|psi-mi:Mttp(display_short)|uniprotkb:Mtp(gene name synonym) psi-mi:vili_mouse(display_long)|uniprotkb:Vil1(gene name)|psi-mi:Vil1(display_short)|uniprotkb:Vil(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183644|imex:IM-11844-8 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001156929.1|refseq:NP_032668.2|ensembl:ENSMUSG00000028158(gene)|ensembl:ENSMUST00000029805(transcript)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006497"(protein lipidation)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009306"(protein secretion)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034197"(triglyceride transport)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034377"(plasma lipoprotein particle assembly)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0006629"(lipid metabolic process)|refseq:XP_006501165.1|refseq:XP_006501166.1|go:"GO:0043235"(receptor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051592"(response to calcium ion)|go:"GO:0120014"(phospholipid transfer activity)|go:"GO:0120019"(phosphatidylcholine transfer activity)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:0140344"(triglyceride transfer activity)|go:"GO:1902388"(ceramide 1-phosphate transfer activity)|go:"GO:1904121"(phosphatidylethanolamine transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR039988|mint:O08601|go:"GO:0042953"(lipoprotein transport)|reactome:R-MMU-8963888|reactome:R-MMU-8866423|refseq:XP_017174963.1|refseq:XP_017174964.1 refseq:NP_033535.2|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|mint:Q62468|go:"GO:1902896"(terminal web assembly)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0032532"(regulation of microvillus length)|ensembl:ENSMUSG00000026175(gene)|ensembl:ENSMUST00000027366(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:7VKaqT/iEzsvkw6SA1aX3ef2sgA10090 rogid:0+lYMSTWQyTkDecT6ZQgeXblR4Y10090 intact-crc:EF55CB7CED858C3E|rigid:HTCHXt3MFMeYOnL1n9ZC/zWce8M false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P97328 uniprotkb:Q9QZ83 intact:EBI-1183661|uniprotkb:Q91WU8 intact:EBI-1183650 psi-mi:khk_mouse(display_long)|uniprotkb:Hepatic fructokinase(gene name synonym)|uniprotkb:Khk(gene name)|psi-mi:Khk(display_short) psi-mi:q9qz83_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actl(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183671|imex:IM-11844-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032465.2|interpro:IPR011611(Carbohydrate/purine kinase)|interpro:IPR029056|go:"GO:0004454"(ketohexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0009744"(response to sucrose)|go:"GO:0009749"(response to glucose)|go:"GO:0009750"(response to fructose)|go:"GO:0010043"(response to zinc ion)|go:"GO:0032868"(response to insulin)|go:"GO:0061624"(fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate)|go:"GO:0061625"(glycolytic process through fructose-1-phosphate)|go:"GO:0070873"(regulation of glycogen metabolic process)|rcsb pdb:6P2D|reactome:R-MMU-70350|interpro:IPR034093|mint:P97328 interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR004001(Actin, conserved site)|mint:Q9QZ83|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:pc5OpmHi5HZmh8hBmpoIK4pUxio10090 rogid:OI3Pd5TCUzMYG4S3c6EieaR38bc10090 intact-crc:92BEB02E8FCE8B1C|rigid:rB2OtpZLFC0/+wTxDoMIuSPdfVs false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P97328 uniprotkb:Q62468 intact:EBI-1183661|uniprotkb:Q91WU8 intact:EBI-1183601|uniprotkb:Q149B6|uniprotkb:Q91WH4|ensembl:ENSMUSP00000027366 psi-mi:khk_mouse(display_long)|uniprotkb:Hepatic fructokinase(gene name synonym)|uniprotkb:Khk(gene name)|psi-mi:Khk(display_short) psi-mi:vili_mouse(display_long)|uniprotkb:Vil1(gene name)|psi-mi:Vil1(display_short)|uniprotkb:Vil(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183671|imex:IM-11844-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032465.2|interpro:IPR011611(Carbohydrate/purine kinase)|interpro:IPR029056|go:"GO:0004454"(ketohexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0009744"(response to sucrose)|go:"GO:0009749"(response to glucose)|go:"GO:0009750"(response to fructose)|go:"GO:0010043"(response to zinc ion)|go:"GO:0032868"(response to insulin)|go:"GO:0061624"(fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate)|go:"GO:0061625"(glycolytic process through fructose-1-phosphate)|go:"GO:0070873"(regulation of glycogen metabolic process)|rcsb pdb:6P2D|reactome:R-MMU-70350|interpro:IPR034093|mint:P97328 refseq:NP_033535.2|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|mint:Q62468|go:"GO:1902896"(terminal web assembly)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0032532"(regulation of microvillus length)|ensembl:ENSMUSG00000026175(gene)|ensembl:ENSMUST00000027366(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:pc5OpmHi5HZmh8hBmpoIK4pUxio10090 rogid:0+lYMSTWQyTkDecT6ZQgeXblR4Y10090 intact-crc:92BEB02E8FCE8B1C|rigid:rB2OtpZLFC0/+wTxDoMIuSPdfVs false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q62468 uniprotkb:Q9QZ83 intact:EBI-1183601|uniprotkb:Q149B6|uniprotkb:Q91WH4|ensembl:ENSMUSP00000027366 intact:EBI-1183650 psi-mi:vili_mouse(display_long)|uniprotkb:Vil1(gene name)|psi-mi:Vil1(display_short)|uniprotkb:Vil(gene name synonym) psi-mi:q9qz83_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actl(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183680|imex:IM-11844-10 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033535.2|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:2000392"(regulation of lamellipodium morphogenesis)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030007|interpro:IPR036180|interpro:IPR036886|mint:Q62468|go:"GO:1902896"(terminal web assembly)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0045010"(actin nucleation)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051125"(regulation of actin nucleation)|go:"GO:0051693"(actin filament capping)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0032532"(regulation of microvillus length)|ensembl:ENSMUSG00000026175(gene)|ensembl:ENSMUST00000027366(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032433"(filopodium tip) interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR004001(Actin, conserved site)|mint:Q9QZ83|interpro:IPR043129 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:0+lYMSTWQyTkDecT6ZQgeXblR4Y10090 rogid:OI3Pd5TCUzMYG4S3c6EieaR38bc10090 intact-crc:710E864D97D30903|rigid:CYCZJttRNmYIIWnbcFWtIe+Verc false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:P26040 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-645505|uniprotkb:Q80ZT8|uniprotkb:Q9DCI1|ensembl:ENSMUSP00000063734 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:ezri_mouse(display_long)|uniprotkb:Vil2(gene name synonym)|uniprotkb:p81(gene name synonym)|uniprotkb:Cytovillin(gene name synonym)|uniprotkb:Villin-2(gene name synonym)|uniprotkb:Ezr(gene name)|psi-mi:Ezr(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183706|imex:IM-11844-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 refseq:NP_033536.2|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031623"(receptor internalization)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044297"(cell body)|go:"GO:0044393"(microspike)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097454"(Schwann cell microvillus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902896"(terminal web assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|interpro:IPR008954(Moesin)|mint:P26040|reactome:R-MMU-373752|reactome:R-MMU-437239|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|ensembl:ENSMUSG00000052397(gene)|ensembl:ENSMUST00000064234(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0001772"(immunological synapse)|go:"GO:0001931"(uropod)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|caution:"The protein identifier for trafficking protein particle complex protein 2 was for a human protein the most similar mouse protein ( Q5J9A9) by amino acid sequence similarity has been entered."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:PspmkV3JA32h1VGLkUgha3a59AA10090 intact-crc:6F363F3003B9C1A4|rigid:5D9RjWJOydSHkzHnFO1AZudcFoM false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:P16627 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-1183684|uniprotkb:O88686|uniprotkb:Q61693|ensembl:ENSMUSP00000007248 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:hs71l_mouse(display_long)|uniprotkb:Heat shock 70 kDa-like protein 1(gene name synonym)|uniprotkb:Spermatid-specific heat shock protein 70(gene name synonym)|uniprotkb:Hspa1l(gene name)|psi-mi:Hspa1l(display_short)|uniprotkb:Hsc70t(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183706|imex:IM-11844-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 refseq:NP_038586.2|ensembl:ENSMUSG00000007033(gene)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030154"(cell differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|ensembl:ENSMUST00000007248(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|reactome:R-MMU-3371453|reactome:R-MMU-3371497|reactome:R-MMU-3371568|reactome:R-MMU-3371571 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|caution:"The protein identifier for trafficking protein particle complex protein 2 was for a human protein the most similar mouse protein ( Q5J9A9) by amino acid sequence similarity has been entered."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:9AyTRM+TusngYdweWsTK46QlIgk10090 intact-crc:6F363F3003B9C1A4|rigid:5D9RjWJOydSHkzHnFO1AZudcFoM false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:Q5J9A9 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-1183693 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:q5j9a9_mouse(display_long)|uniprotkb:Trappc2(gene name)|psi-mi:Trappc2(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183706|imex:IM-11844-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 refseq:NP_079708.2|interpro:IPR011012(Longin-like)|interpro:IPR006722(Sedlin)|refseq:NP_001300651.1|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0048471"(perinuclear region of cytoplasm) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|caution:"The protein identifier for trafficking protein particle complex protein 2 was for a human protein the most similar mouse protein ( Q5J9A9) by amino acid sequence similarity has been entered."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:GLh71F+osh+lZK15VjEPYhsPIfs10090 intact-crc:6F363F3003B9C1A4|rigid:5D9RjWJOydSHkzHnFO1AZudcFoM false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P60710 uniprotkb:P97429 intact:EBI-353957|ensembl:ENSMUSP00000098066|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q3TI89|uniprotkb:Q3TVP6|uniprotkb:Q64316|uniprotkb:Q6ZWM3 intact:EBI-1183723|uniprotkb:Q3UCL0|ensembl:ENSMUSP00000001187|ensembl:ENSMUSP00000109305 psi-mi:actb_mouse(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:anxa4_mouse(display_long)|uniprotkb:Annexin-4(gene name synonym)|uniprotkb:Annexin IV(gene name synonym)|uniprotkb:Anxa4(gene name)|psi-mi:Anxa4(display_short)|uniprotkb:Anx4(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183732|imex:IM-11844-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029580(gene)|ensembl:ENSMUST00000100497(transcript)|refseq:NP_031419.1|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60710|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5250924|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8856828|reactome:R-MMU-9035034|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|dip:DIP-31574N refseq:NP_038499.2|refseq:XP_006505460.1|refseq:XP_006505461.1|ensembl:ENSMUSG00000029994(gene)|ensembl:ENSMUST00000001187(transcript)|ensembl:ENSMUST00000113675(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001464(Annexin)|interpro:IPR002391(Annexin, type IV)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P97429|refseq:NP_001318049.1 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|caution:"The protein identifier for actin-beta protein was for a human protein the most similar mouse protein (P60710) by amino acid sequence similarity has been entered."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10090 rogid:HXqwhs0CVA/5XTybrzpa1L44yH010090 intact-crc:1F49C528A2BFBC6F|rigid:u/JkHMGa+4cHoLmmf5kQAIYc7uI false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P60710 uniprotkb:Q3V0K9 intact:EBI-353957|ensembl:ENSMUSP00000098066|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q3TI89|uniprotkb:Q3TVP6|uniprotkb:Q64316|uniprotkb:Q6ZWM3 intact:EBI-1183739|ensembl:ENSMUSP00000091317 psi-mi:actb_mouse(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:plsi_mouse(display_long)|uniprotkb:Pls1(gene name)|psi-mi:Pls1(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183732|imex:IM-11844-12 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029580(gene)|ensembl:ENSMUST00000100497(transcript)|refseq:NP_031419.1|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60710|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5250924|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8856828|reactome:R-MMU-9035034|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|dip:DIP-31574N refseq:NP_001028382.1|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR030235|interpro:IPR036872|interpro:IPR039959|mint:Q3V0K9|go:"GO:0005903"(brush border)|go:"GO:0032420"(stereocilium)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060121"(vestibular receptor cell stereocilium organization)|go:"GO:1902896"(terminal web assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990357"(terminal web)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|refseq:XP_006510809.1|refseq:XP_006510810.1|ensembl:ENSMUSG00000049493(gene)|ensembl:ENSMUST00000093800(transcript)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|caution:"The protein identifier for actin-beta protein was for a human protein the most similar mouse protein (P60710) by amino acid sequence similarity has been entered."|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10090 rogid:rD1284OOqhjdTNQrrW0IWT9p4VU10090 intact-crc:1F49C528A2BFBC6F|rigid:u/JkHMGa+4cHoLmmf5kQAIYc7uI false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P97429 uniprotkb:Q9R100 intact:EBI-1183723|uniprotkb:Q3UCL0|ensembl:ENSMUSP00000001187|ensembl:ENSMUSP00000109305 intact:EBI-1183765|ensembl:ENSMUSP00000029871 psi-mi:anxa4_mouse(display_long)|uniprotkb:Annexin-4(gene name synonym)|uniprotkb:Annexin IV(gene name synonym)|uniprotkb:Anxa4(gene name)|psi-mi:Anxa4(display_short)|uniprotkb:Anx4(gene name synonym) psi-mi:cad17_mouse(display_long)|uniprotkb:Cdh17(gene name)|psi-mi:Cdh17(display_short)|uniprotkb:Liver-intestine cadherin(gene name synonym)|uniprotkb:BILL-cadherin(gene name synonym)|uniprotkb:P130(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183778|imex:IM-11844-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038499.2|refseq:XP_006505460.1|refseq:XP_006505461.1|ensembl:ENSMUSG00000029994(gene)|ensembl:ENSMUST00000001187(transcript)|ensembl:ENSMUST00000113675(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001464(Annexin)|interpro:IPR002391(Annexin, type IV)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P97429|refseq:NP_001318049.1 refseq:NP_062727.1|ensembl:ENSMUSG00000028217(gene)|ensembl:ENSMUST00000029871(transcript)|go:"GO:0002314"(germinal center B cell differentiation)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0005178"(integrin binding)|go:"GO:0005427"(proton-dependent oligopeptide secondary active transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006857"(oligopeptide transport)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0030054"(cell junction)|go:"GO:0030183"(B cell differentiation)|go:"GO:0033626"(positive regulation of integrin activation by cell surface receptor linked signal transduction)|go:"GO:0045296"(cadherin binding)|go:"GO:0048536"(spleen development)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR002126(Cadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR039808|reactome:R-MMU-418990|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|refseq:XP_006537646.1|refseq:XP_006537647.1 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:HXqwhs0CVA/5XTybrzpa1L44yH010090 rogid:usH2J4SJ8YmqcY9r2MOXH+hbvEs10090 intact-crc:0500DED56D0D71F2|rigid:bqwERWIa/R7pqVVyAkLVec0ZM/4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P97429 uniprotkb:P27773 intact:EBI-1183723|uniprotkb:Q3UCL0|ensembl:ENSMUSP00000001187|ensembl:ENSMUSP00000109305 intact:EBI-1183750|uniprotkb:Q3TEI9|uniprotkb:Q3TIL2|uniprotkb:Q3UZK8|uniprotkb:Q8C2F4|uniprotkb:Q99LF6|ensembl:ENSMUSP00000028683 psi-mi:anxa4_mouse(display_long)|uniprotkb:Annexin-4(gene name synonym)|uniprotkb:Annexin IV(gene name synonym)|uniprotkb:Anxa4(gene name)|psi-mi:Anxa4(display_short)|uniprotkb:Anx4(gene name synonym) psi-mi:pdia3_mouse(display_long)|uniprotkb:Pdia3(gene name)|psi-mi:Pdia3(display_short)|uniprotkb:Erp(gene name synonym)|uniprotkb:Erp60(gene name synonym)|uniprotkb:Grp58(gene name synonym)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183778|imex:IM-11844-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038499.2|refseq:XP_006505460.1|refseq:XP_006505461.1|ensembl:ENSMUSG00000029994(gene)|ensembl:ENSMUST00000001187(transcript)|ensembl:ENSMUST00000113675(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001464(Annexin)|interpro:IPR002391(Annexin, type IV)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P97429|refseq:NP_001318049.1 refseq:NP_031978.2|ensembl:ENSMUSG00000027248(gene)|ensembl:ENSMUST00000028683(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0008233"(peptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0043209"(myelin sheath)|go:"GO:0019153"("protein-disulfide reductase (glutathione) activity")|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:1903334"(positive regulation of protein folding)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|go:"GO:0042470"(melanosome)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|go:"GO:0042802"(identical protein binding)|interpro:IPR036249|go:"GO:0042824"(MHC class I peptide loading complex)|interpro:IPR041868|mint:P27773|reactome:R-MMU-1236974|reactome:R-MMU-901042|reactome:R-MMU-983170|go:"GO:0042825"(TAP complex) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:HXqwhs0CVA/5XTybrzpa1L44yH010090 rogid:cG7tGYAi8ElGXs7VmhY3M63GiRc10090 intact-crc:0500DED56D0D71F2|rigid:bqwERWIa/R7pqVVyAkLVec0ZM/4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:P07724 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-1183810|uniprotkb:Q3TV03|uniprotkb:Q61802|uniprotkb:Q8C7C7|uniprotkb:Q8C7H3|uniprotkb:Q8CG74|ensembl:ENSMUSP00000031314 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:albu_mouse(display_long)|uniprotkb:Alb(gene name)|psi-mi:Alb(display_short)|uniprotkb:Alb1(gene name synonym)|uniprotkb:Alb-1(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183838|imex:IM-11844-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 refseq:NP_033784.2|ensembl:ENSMUSG00000029368(gene)|ensembl:ENSMUST00000031314(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015643"(toxic substance binding)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0051087"(chaperone binding)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072341"(modified amino acid binding)|go:"GO:0140272"(exogenous protein binding)|go:"GO:1903981"(enterobactin binding)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|mint:P07724|reactome:R-MMU-114608|reactome:R-MMU-159418|reactome:R-MMU-189451|reactome:R-MMU-189483|reactome:R-MMU-2168880|reactome:R-MMU-381426|reactome:R-MMU-879518|reactome:R-MMU-8957275|reactome:R-MMU-8964058|reactome:R-MMU-9707564 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:R7zO/mB332rAl8J+WrXfsHzjSYs10090 intact-crc:651A526620A5667B|rigid:M/s43K4z/qhUHTVG1pRnS0z9dQ4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:Q8BK48 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-1183784|ensembl:ENSMUSP00000034355|ensembl:ENSMUSP00000105037|uniprotkb:Q8BM97|uniprotkb:Q8VC02 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:est2e_mouse(display_long)|uniprotkb:Ces2e(gene name)|psi-mi:Ces2e(display_short)|uniprotkb:Ces5(gene name synonym)|uniprotkb:carboxylesterase 2E(gene name synonym)|uniprotkb:Carboxylic ester hydrolase(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183838|imex:IM-11844-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 ensembl:ENSMUSG00000031886(gene)|ensembl:ENSMUST00000034355(transcript)|ensembl:ENSMUST00000109410(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0047376"(all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0102209"(trans-permethrin hydrolase activity)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|mint:Q8BK48|refseq:NP_001157228.1|refseq:NP_766347.1 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:YO8Xj/84cjZFE/k7FlZ1SGriPOc10090 intact-crc:651A526620A5667B|rigid:M/s43K4z/qhUHTVG1pRnS0z9dQ4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:Q9DAS9 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-1183804|uniprotkb:Q544P3|ensembl:ENSMUSP00000046557|ensembl:ENSMUSP00000109860|ensembl:ENSMUSP00000109862|ensembl:ENSMUSP00000109863|ensembl:ENSMUSP00000109864|ensembl:ENSMUSP00000109865|ensembl:ENSMUSP00000109866 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:gbg12_mouse(display_long)|uniprotkb:Gng12(gene name)|psi-mi:Gng12(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183838|imex:IM-11844-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 refseq:NP_001171027.1|refseq:NP_001171028.1|refseq:NP_001171029.1|refseq:NP_001171030.1|refseq:NP_001171031.1|refseq:NP_079554.1|ensembl:ENSMUSG00000036402(gene)|ensembl:ENSMUST00000043148(transcript)|ensembl:ENSMUST00000114222(transcript)|ensembl:ENSMUST00000114224(transcript)|ensembl:ENSMUST00000114225(transcript)|ensembl:ENSMUST00000114226(transcript)|ensembl:ENSMUST00000114227(transcript)|ensembl:ENSMUST00000114228(transcript)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0042301"(phosphate ion binding)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|reactome:R-MMU-1296041|reactome:R-MMU-202040|reactome:R-MMU-381676|reactome:R-MMU-392170|reactome:R-MMU-392451|reactome:R-MMU-392851|reactome:R-MMU-400042|reactome:R-MMU-4086398|reactome:R-MMU-416476|reactome:R-MMU-416482|reactome:R-MMU-418217|reactome:R-MMU-418555|reactome:R-MMU-418592|reactome:R-MMU-418594|reactome:R-MMU-418597|reactome:R-MMU-420092|reactome:R-MMU-428930|reactome:R-MMU-432040|reactome:R-MMU-456926|reactome:R-MMU-500657|reactome:R-MMU-6814122|reactome:R-MMU-8964315|reactome:R-MMU-8964616|reactome:R-MMU-9009391|reactome:R-MMU-997272|refseq:XP_006505605.1 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:29C/KggTANGedW9+lPzudGdahYk10090 intact-crc:651A526620A5667B|rigid:M/s43K4z/qhUHTVG1pRnS0z9dQ4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:P14206 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-1183792|ensembl:ENSMUSP00000035105|ensembl:ENSMUSP00000148933|uniprotkb:Q58E74|uniprotkb:Q8BHL0|uniprotkb:Q8BNL2|uniprotkb:Q91V31|uniprotkb:Q9CY13 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:rssa_mouse(display_long)|uniprotkb:Rpsa(gene name)|psi-mi:Rpsa(display_short)|uniprotkb:Lamr1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:37 kDa oncofetal antigen(gene name synonym)|uniprotkb:OFA/iLRP(gene name synonym)|uniprotkb:P40-8(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183838|imex:IM-11844-14 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 ensembl:ENSMUSG00000032518(gene)|refseq:NP_035159.3|ensembl:ENSMUST00000035105(transcript)|ensembl:ENSMUST00000217317(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043022"(ribosome binding)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P14206|reactome:R-MMU-156827|go:"GO:0043025"(neuronal cell body)|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0043236"(laminin binding)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001865(Ribosomal protein S2)|dip:DIP-38089N psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:Qf5VO9t+mZnGd/vuxHsQyYBuYSQ10090 intact-crc:651A526620A5667B|rigid:M/s43K4z/qhUHTVG1pRnS0z9dQ4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P63260 uniprotkb:P68134 intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183863|imex:IM-11844-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608 refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 intact-crc:339CED131DB1DB37|rigid:ut80r0sCJ0ZnFA0zbqOKaZdlOt4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P63260 uniprotkb:P14211 intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822 intact:EBI-644340|ensembl:ENSMUSP00000003912|uniprotkb:Q3TVD2 psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:calr_mouse(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:Calr(gene name)|psi-mi:Calr(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183863|imex:IM-11844-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608 refseq:NP_031617.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0060473"(cortical granule)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0090398"(cellular senescence)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|go:"GO:0008284"(positive regulation of cell population proliferation)|interpro:IPR018124|mint:P14211|rcsb pdb:3O0V|rcsb pdb:3O0W|rcsb pdb:3O0X|rcsb pdb:3RG0|go:"GO:0009897"(external side of plasma membrane)|reactome:R-MMU-1236974|reactome:R-MMU-3000480|reactome:R-MMU-901042|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|ensembl:ENSMUSG00000003814(gene)|ensembl:ENSMUST00000003912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002502"(peptide antigen assembly with MHC class I protein complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|reactome:R-MMU-983170 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090 rogid:/yN2nHI8x9rWoJO+b+2dYGxOgf010090 intact-crc:339CED131DB1DB37|rigid:ut80r0sCJ0ZnFA0zbqOKaZdlOt4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P63260 uniprotkb:Q8QZR3 intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822 intact:EBI-1183847|ensembl:ENSMUSP00000034346|uniprotkb:E9Q3D0|uniprotkb:Q3TMR2 psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:est2a_mouse(display_long)|uniprotkb:Ces2a(gene name)|psi-mi:Ces2a(display_short)|uniprotkb:Ces6(gene name synonym)|uniprotkb:carboxylesterase 2A(gene name synonym)|uniprotkb:Carboxylic ester hydrolase 2A(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183863|imex:IM-11844-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608 refseq:NP_001177259.1|refseq:NP_598721.1|ensembl:ENSMUSG00000055730(gene)|ensembl:ENSMUST00000034346(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006486"(protein glycosylation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0047376"(all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0102209"(trans-permethrin hydrolase activity)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|mint:Q8QZR3 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090 rogid:EjLqTByKP0zDbbZIibX/KodHn+410090 intact-crc:339CED131DB1DB37|rigid:ut80r0sCJ0ZnFA0zbqOKaZdlOt4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P63260 uniprotkb:O55022 intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822 intact:EBI-770756|uniprotkb:Q99JN0|ensembl:ENSMUSP00000073061 psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:pgrc1_mouse(display_long)|uniprotkb:Pgrmc1(gene name)|psi-mi:Pgrmc1(display_short)|uniprotkb:Pgrmc(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183863|imex:IM-11844-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608 refseq:NP_058063.2|ensembl:ENSMUSG00000006373(gene)|ensembl:ENSMUST00000073339(transcript)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0007613"(memory)|go:"GO:0008306"(associative learning)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905809"(negative regulation of synapse organization)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O55022|reactome:R-MMU-6798695 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090 rogid:JJb2/xwky1pSXG+DPfq5+XVmbcw10090 intact-crc:339CED131DB1DB37|rigid:ut80r0sCJ0ZnFA0zbqOKaZdlOt4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P63260 uniprotkb:P68134 intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183885|imex:IM-11844-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608 refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 intact-crc:9861CA02C65B9F10|rigid:hhYmzZzfE3kuxT8UXPN0OQMU7nI false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P63260 uniprotkb:Q8K419 intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822 intact:EBI-1183873|uniprotkb:O88353|uniprotkb:Q91X74|ensembl:ENSMUSP00000066461 psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:leg4_mouse(display_long)|uniprotkb:Lgals4(gene name)|psi-mi:Lgals4(display_short)|uniprotkb:Lactose-binding lectin 4(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183885|imex:IM-11844-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608 refseq:NP_034836.1|ensembl:ENSMUSG00000053964(gene)|ensembl:ENSMUST00000066723(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0016936"(galactoside binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015533(Galectin-4/6)|interpro:IPR044156|rcsb pdb:2DYC|rcsb pdb:3I8T psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090 rogid:CxB7/h34xwEn/pCyuUyG5RQSJsQ10090 intact-crc:9861CA02C65B9F10|rigid:hhYmzZzfE3kuxT8UXPN0OQMU7nI false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P63260 uniprotkb:P09103 intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822 intact:EBI-494709|uniprotkb:Q922C8|ensembl:ENSMUSP00000026122 psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:pdia1_mouse(display_long)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 59(gene name synonym)|uniprotkb:P4hb(gene name)|psi-mi:P4hb(display_short)|uniprotkb:Pdia1(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183885|imex:IM-11844-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608 refseq:NP_035162.1|ensembl:ENSMUSG00000025130(gene)|ensembl:ENSMUST00000026122(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P09103|reactome:R-MMU-1650814|reactome:R-MMU-3299685|reactome:R-MMU-381426|reactome:R-MMU-5358346|reactome:R-MMU-8866423|reactome:R-MMU-8957275|reactome:R-MMU-8963888|reactome:R-MMU-9020591|reactome:R-MMU-9020933 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090 rogid:j20LBPF1r9AYUdJAgzNS/+Uq8GY10090 intact-crc:9861CA02C65B9F10|rigid:hhYmzZzfE3kuxT8UXPN0OQMU7nI false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P63260 uniprotkb:O55022 intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822 intact:EBI-770756|uniprotkb:Q99JN0|ensembl:ENSMUSP00000073061 psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:pgrc1_mouse(display_long)|uniprotkb:Pgrmc1(gene name)|psi-mi:Pgrmc1(display_short)|uniprotkb:Pgrmc(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183885|imex:IM-11844-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608 refseq:NP_058063.2|ensembl:ENSMUSG00000006373(gene)|ensembl:ENSMUST00000073339(transcript)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0007613"(memory)|go:"GO:0008306"(associative learning)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905809"(negative regulation of synapse organization)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O55022|reactome:R-MMU-6798695 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090 rogid:JJb2/xwky1pSXG+DPfq5+XVmbcw10090 intact-crc:9861CA02C65B9F10|rigid:hhYmzZzfE3kuxT8UXPN0OQMU7nI false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P63260 uniprotkb:P14206 intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822 intact:EBI-1183792|ensembl:ENSMUSP00000035105|ensembl:ENSMUSP00000148933|uniprotkb:Q58E74|uniprotkb:Q8BHL0|uniprotkb:Q8BNL2|uniprotkb:Q91V31|uniprotkb:Q9CY13 psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:rssa_mouse(display_long)|uniprotkb:Rpsa(gene name)|psi-mi:Rpsa(display_short)|uniprotkb:Lamr1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:37 kDa oncofetal antigen(gene name synonym)|uniprotkb:OFA/iLRP(gene name synonym)|uniprotkb:P40-8(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183885|imex:IM-11844-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608 ensembl:ENSMUSG00000032518(gene)|refseq:NP_035159.3|ensembl:ENSMUST00000035105(transcript)|ensembl:ENSMUST00000217317(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043022"(ribosome binding)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P14206|reactome:R-MMU-156827|go:"GO:0043025"(neuronal cell body)|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0043236"(laminin binding)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001865(Ribosomal protein S2)|dip:DIP-38089N psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090 rogid:Qf5VO9t+mZnGd/vuxHsQyYBuYSQ10090 intact-crc:9861CA02C65B9F10|rigid:hhYmzZzfE3kuxT8UXPN0OQMU7nI false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P63260 uniprotkb:P68134 intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183937|imex:IM-11844-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608 refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 intact-crc:A8A7F08D951FC419|rigid:Pvzh1dfXCZvhnVBn0U7G6m187g4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P63260 uniprotkb:Q99JG3 intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822 intact:EBI-646311|ensembl:ENSMUSP00000159441 psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:anx13_mouse(display_long)|uniprotkb:Annexin-13(gene name synonym)|uniprotkb:Annexin XIII(gene name synonym)|uniprotkb:Anxa13(gene name)|psi-mi:Anxa13(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183937|imex:IM-11844-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608 refseq:NP_081487.1|ensembl:ENSMUSG00000055114(gene)|ensembl:ENSMUST00000227274(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:1901611"(phosphatidylglycerol binding)|interpro:IPR001464(Annexin)|interpro:IPR009166(Annexin, type XIII)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090 rogid:G6kLdiQp0ADoF7kiV4h+jomoRxw10090 intact-crc:A8A7F08D951FC419|rigid:Pvzh1dfXCZvhnVBn0U7G6m187g4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P63260 uniprotkb:P97429 intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822 intact:EBI-1183723|uniprotkb:Q3UCL0|ensembl:ENSMUSP00000001187|ensembl:ENSMUSP00000109305 psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:anxa4_mouse(display_long)|uniprotkb:Annexin-4(gene name synonym)|uniprotkb:Annexin IV(gene name synonym)|uniprotkb:Anxa4(gene name)|psi-mi:Anxa4(display_short)|uniprotkb:Anx4(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183937|imex:IM-11844-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608 refseq:NP_038499.2|refseq:XP_006505460.1|refseq:XP_006505461.1|ensembl:ENSMUSG00000029994(gene)|ensembl:ENSMUST00000001187(transcript)|ensembl:ENSMUST00000113675(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001464(Annexin)|interpro:IPR002391(Annexin, type IV)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P97429|refseq:NP_001318049.1 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090 rogid:HXqwhs0CVA/5XTybrzpa1L44yH010090 intact-crc:A8A7F08D951FC419|rigid:Pvzh1dfXCZvhnVBn0U7G6m187g4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P63260 uniprotkb:P14211 intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822 intact:EBI-644340|ensembl:ENSMUSP00000003912|uniprotkb:Q3TVD2 psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:calr_mouse(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:Calr(gene name)|psi-mi:Calr(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183937|imex:IM-11844-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608 refseq:NP_031617.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0060473"(cortical granule)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0090398"(cellular senescence)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|go:"GO:0008284"(positive regulation of cell population proliferation)|interpro:IPR018124|mint:P14211|rcsb pdb:3O0V|rcsb pdb:3O0W|rcsb pdb:3O0X|rcsb pdb:3RG0|go:"GO:0009897"(external side of plasma membrane)|reactome:R-MMU-1236974|reactome:R-MMU-3000480|reactome:R-MMU-901042|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|ensembl:ENSMUSG00000003814(gene)|ensembl:ENSMUST00000003912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002502"(peptide antigen assembly with MHC class I protein complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|reactome:R-MMU-983170 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090 rogid:/yN2nHI8x9rWoJO+b+2dYGxOgf010090 intact-crc:A8A7F08D951FC419|rigid:Pvzh1dfXCZvhnVBn0U7G6m187g4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P63260 uniprotkb:P09103 intact:EBI-351301|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|ensembl:ENSMUSP00000071486|ensembl:ENSMUSP00000101822 intact:EBI-494709|uniprotkb:Q922C8|ensembl:ENSMUSP00000026122 psi-mi:actg_mouse(display_long)|uniprotkb:Actg1(gene name)|psi-mi:Actg1(display_short)|uniprotkb:Actg(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym) psi-mi:pdia1_mouse(display_long)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 59(gene name synonym)|uniprotkb:P4hb(gene name)|psi-mi:P4hb(display_short)|uniprotkb:Pdia1(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183937|imex:IM-11844-17 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033739.1|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-8856828|reactome:R-MMU-9013418|ensembl:ENSMUSG00000062825(gene)|ensembl:ENSMUST00000071555(transcript)|ensembl:ENSMUST00000106215(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045177"(apical part of cell)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099143"(presynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|reactome:R-MMU-114608 refseq:NP_035162.1|ensembl:ENSMUSG00000025130(gene)|ensembl:ENSMUST00000026122(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P09103|reactome:R-MMU-1650814|reactome:R-MMU-3299685|reactome:R-MMU-381426|reactome:R-MMU-5358346|reactome:R-MMU-8866423|reactome:R-MMU-8957275|reactome:R-MMU-8963888|reactome:R-MMU-9020591|reactome:R-MMU-9020933 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY10090 rogid:j20LBPF1r9AYUdJAgzNS/+Uq8GY10090 intact-crc:A8A7F08D951FC419|rigid:Pvzh1dfXCZvhnVBn0U7G6m187g4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:Q99JG3 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-646311|ensembl:ENSMUSP00000159441 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:anx13_mouse(display_long)|uniprotkb:Annexin-13(gene name synonym)|uniprotkb:Annexin XIII(gene name synonym)|uniprotkb:Anxa13(gene name)|psi-mi:Anxa13(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183981|imex:IM-11844-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 refseq:NP_081487.1|ensembl:ENSMUSG00000055114(gene)|ensembl:ENSMUST00000227274(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:1901611"(phosphatidylglycerol binding)|interpro:IPR001464(Annexin)|interpro:IPR009166(Annexin, type XIII)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:G6kLdiQp0ADoF7kiV4h+jomoRxw10090 intact-crc:38BDAAE32BEE1A08|rigid:jnEYt1smcOpO9R6ZVAaPdgQobtQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:P97429 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-1183723|uniprotkb:Q3UCL0|ensembl:ENSMUSP00000001187|ensembl:ENSMUSP00000109305 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:anxa4_mouse(display_long)|uniprotkb:Annexin-4(gene name synonym)|uniprotkb:Annexin IV(gene name synonym)|uniprotkb:Anxa4(gene name)|psi-mi:Anxa4(display_short)|uniprotkb:Anx4(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183981|imex:IM-11844-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 refseq:NP_038499.2|refseq:XP_006505460.1|refseq:XP_006505461.1|ensembl:ENSMUSG00000029994(gene)|ensembl:ENSMUST00000001187(transcript)|ensembl:ENSMUST00000113675(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001464(Annexin)|interpro:IPR002391(Annexin, type IV)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P97429|refseq:NP_001318049.1 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:HXqwhs0CVA/5XTybrzpa1L44yH010090 intact-crc:38BDAAE32BEE1A08|rigid:jnEYt1smcOpO9R6ZVAaPdgQobtQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:P14211 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-644340|ensembl:ENSMUSP00000003912|uniprotkb:Q3TVD2 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:calr_mouse(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:Calr(gene name)|psi-mi:Calr(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183981|imex:IM-11844-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 refseq:NP_031617.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0060473"(cortical granule)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0090398"(cellular senescence)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|go:"GO:0008284"(positive regulation of cell population proliferation)|interpro:IPR018124|mint:P14211|rcsb pdb:3O0V|rcsb pdb:3O0W|rcsb pdb:3O0X|rcsb pdb:3RG0|go:"GO:0009897"(external side of plasma membrane)|reactome:R-MMU-1236974|reactome:R-MMU-3000480|reactome:R-MMU-901042|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|ensembl:ENSMUSG00000003814(gene)|ensembl:ENSMUST00000003912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002502"(peptide antigen assembly with MHC class I protein complex)|go:"GO:0003729"(mRNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|reactome:R-MMU-983170 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:/yN2nHI8x9rWoJO+b+2dYGxOgf010090 intact-crc:38BDAAE32BEE1A08|rigid:jnEYt1smcOpO9R6ZVAaPdgQobtQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:Q8BXK9 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-1183952|uniprotkb:Q3U0H8|ensembl:ENSMUSP00000024755 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:clic5_mouse(display_long)|uniprotkb:Clic5(gene name)|psi-mi:Clic5(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183981|imex:IM-11844-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 refseq:NP_766209.1|ensembl:ENSMUSG00000023959(gene)|ensembl:ENSMUST00000024755(transcript)|go:"GO:0002021"(response to dietary excess)|go:"GO:0002024"(diet induced thermogenesis)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006821"(chloride transport)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008104"(protein localization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|interpro:IPR002946(Intracellular chloride channel)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR030264|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|interpro:IPR042069|mint:Q8BXK9|go:"GO:0034707"(chloride channel complex) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:VV/Z0uczERV7zb3sWU7jmtfxCFY10090 intact-crc:38BDAAE32BEE1A08|rigid:jnEYt1smcOpO9R6ZVAaPdgQobtQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:Q63880 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-1183947|uniprotkb:Q3UEJ0|uniprotkb:Q3UU08|uniprotkb:Q6P8Z0|uniprotkb:Q6PG74|uniprotkb:Q810S9|ensembl:ENSMUSP00000090910 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:est3a_mouse(display_long)|uniprotkb:Ces3a(gene name)|psi-mi:Ces3a(display_short)|uniprotkb:ES-male(gene name synonym)|uniprotkb:Es31(gene name synonym)|uniprotkb:Liver carboxylesterase 31(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183981|imex:IM-11844-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 refseq:NP_001158153.1|refseq:NP_941074.1|ensembl:ENSMUSG00000069922(gene)|ensembl:ENSMUST00000093222(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0080030"(methyl indole-3-acetate esterase activity)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|mint:Q63880 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:YViZVm/VfmUKV8dX4bg17q9Qg9I10090 intact-crc:38BDAAE32BEE1A08|rigid:jnEYt1smcOpO9R6ZVAaPdgQobtQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:O55022 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-770756|uniprotkb:Q99JN0|ensembl:ENSMUSP00000073061 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:pgrc1_mouse(display_long)|uniprotkb:Pgrmc1(gene name)|psi-mi:Pgrmc1(display_short)|uniprotkb:Pgrmc(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183981|imex:IM-11844-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 refseq:NP_058063.2|ensembl:ENSMUSG00000006373(gene)|ensembl:ENSMUST00000073339(transcript)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0007613"(memory)|go:"GO:0008306"(associative learning)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905809"(negative regulation of synapse organization)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O55022|reactome:R-MMU-6798695 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:JJb2/xwky1pSXG+DPfq5+XVmbcw10090 intact-crc:38BDAAE32BEE1A08|rigid:jnEYt1smcOpO9R6ZVAaPdgQobtQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:P68040 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-296749|ensembl:ENSMUSP00000020640|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-1183965|uniprotkb:Q3THP0|uniprotkb:Q3THY7|uniprotkb:Q3TKQ0|uniprotkb:Q3TW88|uniprotkb:Q5NCC5|uniprotkb:Q5NCC6|uniprotkb:Q9CSQ0|uniprotkb:Q9ERM6 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:rack1_mouse(display_long)|uniprotkb:p205(gene name synonym)|uniprotkb:Receptor of activated protein kinase C 1(gene name synonym)|uniprotkb:12-3(gene name synonym)|uniprotkb:Gnb2-rs1(gene name synonym)|uniprotkb:Gnb2l1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Rack1(gene name)|psi-mi:Rack1(display_short)|uniprotkb:Receptor for activated C kinase(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183981|imex:IM-11844-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P68040|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5626978|go:"GO:0072344"(rescue of stalled ribosome)|ensembl:ENSMUSG00000020372(gene)|ensembl:ENSMUST00000020640(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008104"(protein localization)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0006412"(translation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044297"(cell body)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|refseq:NP_032169.1 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:LXHlhPtxUzHJNncoPteGw2iXsFg10090 intact-crc:38BDAAE32BEE1A08|rigid:jnEYt1smcOpO9R6ZVAaPdgQobtQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P68134 uniprotkb:P62082 intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453 intact:EBI-354350|uniprotkb:P24818|uniprotkb:P23821|ensembl:ENSMUSP00000073880|ensembl:ENSMUSP00000152456 psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym) psi-mi:rs7_mouse(display_long)|uniprotkb:Rps7(gene name)|psi-mi:Rps7(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1183981|imex:IM-11844-18 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1 refseq:NP_035430.1|ensembl:ENSMUSG00000061477(gene)|ensembl:ENSMUST00000074267(transcript)|ensembl:ENSMUST00000221871(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000554(Ribosomal protein S7e)|mint:P62082|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0032040"(small-subunit processome) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090 rogid:l4aG6I34lmzYhNapbdv2CAAwRwg10090 intact-crc:38BDAAE32BEE1A08|rigid:jnEYt1smcOpO9R6ZVAaPdgQobtQ false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q99P81 uniprotkb:O88312 intact:EBI-1184072|uniprotkb:Q8BKI5|ensembl:ENSMUSP00000031239 intact:EBI-1184057|uniprotkb:A2CGA2|ensembl:ENSMUSP00000020898 psi-mi:abcg3_mouse(display_long)|uniprotkb:Abcg3(gene name)|psi-mi:Abcg3(display_short) psi-mi:agr2_mouse(display_long)|uniprotkb:Agr2(gene name)|psi-mi:Agr2(display_short)|uniprotkb:Gob4(gene name synonym)|uniprotkb:Secreted cement gland protein XAG-2 homolog(gene name synonym)|uniprotkb:Protein Gob-4(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184095|imex:IM-11844-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084515.2|ensembl:ENSMUSG00000029299(gene)|ensembl:ENSMUST00000031239(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR043926 refseq:NP_035913.1|ensembl:ENSMUSG00000020581(gene)|ensembl:ENSMUST00000020898(transcript)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070254"(mucus secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|interpro:IPR036249|mint:O88312 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:DOTC+j1BapP+v6GCsY0vDXUKsPE10090 rogid:DMbGKpEw+3xscUvpo5jzbZfMJ0s10090 intact-crc:DB6AD949374E760A|rigid:yn5f5573XfLLHHBsyrg6Yy9V0ww false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q99P81 uniprotkb:Q99JG3 intact:EBI-1184072|uniprotkb:Q8BKI5|ensembl:ENSMUSP00000031239 intact:EBI-646311|ensembl:ENSMUSP00000159441 psi-mi:abcg3_mouse(display_long)|uniprotkb:Abcg3(gene name)|psi-mi:Abcg3(display_short) psi-mi:anx13_mouse(display_long)|uniprotkb:Annexin-13(gene name synonym)|uniprotkb:Annexin XIII(gene name synonym)|uniprotkb:Anxa13(gene name)|psi-mi:Anxa13(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184095|imex:IM-11844-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084515.2|ensembl:ENSMUSG00000029299(gene)|ensembl:ENSMUST00000031239(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR043926 refseq:NP_081487.1|ensembl:ENSMUSG00000055114(gene)|ensembl:ENSMUST00000227274(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:1901611"(phosphatidylglycerol binding)|interpro:IPR001464(Annexin)|interpro:IPR009166(Annexin, type XIII)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:DOTC+j1BapP+v6GCsY0vDXUKsPE10090 rogid:G6kLdiQp0ADoF7kiV4h+jomoRxw10090 intact-crc:DB6AD949374E760A|rigid:yn5f5573XfLLHHBsyrg6Yy9V0ww false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q99P81 uniprotkb:P97429 intact:EBI-1184072|uniprotkb:Q8BKI5|ensembl:ENSMUSP00000031239 intact:EBI-1183723|uniprotkb:Q3UCL0|ensembl:ENSMUSP00000001187|ensembl:ENSMUSP00000109305 psi-mi:abcg3_mouse(display_long)|uniprotkb:Abcg3(gene name)|psi-mi:Abcg3(display_short) psi-mi:anxa4_mouse(display_long)|uniprotkb:Annexin-4(gene name synonym)|uniprotkb:Annexin IV(gene name synonym)|uniprotkb:Anxa4(gene name)|psi-mi:Anxa4(display_short)|uniprotkb:Anx4(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184095|imex:IM-11844-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084515.2|ensembl:ENSMUSG00000029299(gene)|ensembl:ENSMUST00000031239(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR043926 refseq:NP_038499.2|refseq:XP_006505460.1|refseq:XP_006505461.1|ensembl:ENSMUSG00000029994(gene)|ensembl:ENSMUST00000001187(transcript)|ensembl:ENSMUST00000113675(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001464(Annexin)|interpro:IPR002391(Annexin, type IV)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P97429|refseq:NP_001318049.1 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:DOTC+j1BapP+v6GCsY0vDXUKsPE10090 rogid:HXqwhs0CVA/5XTybrzpa1L44yH010090 intact-crc:DB6AD949374E760A|rigid:yn5f5573XfLLHHBsyrg6Yy9V0ww false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q99P81 uniprotkb:P60766 intact:EBI-1184072|uniprotkb:Q8BKI5|ensembl:ENSMUSP00000031239 intact:EBI-81763|ensembl:ENSMUSP00000054634|uniprotkb:A2A9U6|uniprotkb:P21181|uniprotkb:P25763|uniprotkb:Q3THZ7|uniprotkb:Q3TJK6|uniprotkb:Q545V0|uniprotkb:Q6P201|uniprotkb:Q8BQ51 psi-mi:abcg3_mouse(display_long)|uniprotkb:Abcg3(gene name)|psi-mi:Abcg3(display_short) psi-mi:cdc42_mouse(display_long)|uniprotkb:Cdc42(gene name)|psi-mi:Cdc42(display_short)|uniprotkb:G25K GTP-binding protein(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184095|imex:IM-11844-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084515.2|ensembl:ENSMUSG00000029299(gene)|ensembl:ENSMUST00000031239(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR043926 ensembl:ENSMUSG00000006699(gene)|ensembl:ENSMUST00000051477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000322"(storage vacuole)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007015"(actin filament organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|refseq:NP_033991.1|go:"GO:0007097"(nuclear migration)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016477"(cell migration)|go:"GO:0017119"(Golgi transport complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030141"(secretory granule)|go:"GO:0030175"(filopodium)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030496"(midbody)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032427"(GBD domain binding)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0034329"(cell junction assembly)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0038189"(neuropilin signaling pathway)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0043209"(myelin sheath)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0051233"(spindle midzone)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051647"(nucleus localization)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0060047"(heart contraction)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060661"(submandibular salivary gland formation)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071944"(cell periphery)|go:"GO:0072384"(organelle transport along microtubule)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090135"(actin filament branching)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037874|mint:P60766|rcsb pdb:3EG5|rcsb pdb:5C2J|reactome:R-MMU-114604|reactome:R-MMU-182971|reactome:R-MMU-2029482|reactome:R-MMU-389359|reactome:R-MMU-3928662|reactome:R-MMU-418885|reactome:R-MMU-4420097|reactome:R-MMU-525793|reactome:R-MMU-5625970|reactome:R-MMU-5626467|reactome:R-MMU-5627123|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5687128|reactome:R-MMU-8964616|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013406|reactome:R-MMU-9013408|reactome:R-MMU-9013420|reactome:R-MMU-9013423|reactome:R-MMU-9013424|reactome:R-MMU-983231|go:"GO:0048664"(neuron fate determination)|refseq:NP_001230698.1|dip:DIP-32554N psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:DOTC+j1BapP+v6GCsY0vDXUKsPE10090 rogid:jiYEHWm+9LQyVj0eUGZOBGaajyU10090 intact-crc:DB6AD949374E760A|rigid:yn5f5573XfLLHHBsyrg6Yy9V0ww false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q99P81 uniprotkb:P18760 intact:EBI-1184072|uniprotkb:Q8BKI5|ensembl:ENSMUSP00000031239 intact:EBI-1183994|ensembl:ENSMUSP00000147514 psi-mi:abcg3_mouse(display_long)|uniprotkb:Abcg3(gene name)|psi-mi:Abcg3(display_short) psi-mi:cof1_mouse(display_long)|uniprotkb:Cfl1(gene name)|psi-mi:Cfl1(display_short)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184095|imex:IM-11844-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084515.2|ensembl:ENSMUSG00000029299(gene)|ensembl:ENSMUST00000031239(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR043926 refseq:NP_031713.1|ensembl:ENSMUSG00000056201(gene)|ensembl:ENSMUST00000209469(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001842"(neural fold formation)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030175"(filopodium)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030426"(growth cone)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043200"(response to amino acid)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051511"(negative regulation of unidimensional cell growth)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090732"(cofilin-actin rod)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904783"(positive regulation of NMDA glutamate receptor activity)|go:"GO:1905873"(positive regulation of protein localization to cell leading edge)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|go:"GO:2000814"(positive regulation of barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P18760|dip:DIP-38073N psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:DOTC+j1BapP+v6GCsY0vDXUKsPE10090 rogid:nw/9u2+2nq9Ef43SapV43MeOtjE10090 intact-crc:DB6AD949374E760A|rigid:yn5f5573XfLLHHBsyrg6Yy9V0ww false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q99P81 uniprotkb:Q9R0P5 intact:EBI-1184072|uniprotkb:Q8BKI5|ensembl:ENSMUSP00000031239 intact:EBI-1184008|ensembl:ENSMUSP00000099461 psi-mi:abcg3_mouse(display_long)|uniprotkb:Abcg3(gene name)|psi-mi:Abcg3(display_short) psi-mi:dest_mouse(display_long)|uniprotkb:Dstn(gene name)|psi-mi:Dstn(display_short)|uniprotkb:Dsn(gene name synonym)|uniprotkb:Sid23(gene name synonym)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Sid 23(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184095|imex:IM-11844-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084515.2|ensembl:ENSMUSG00000029299(gene)|ensembl:ENSMUST00000031239(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR043926 refseq:NP_062745.1|ensembl:ENSMUSG00000015932(gene)|ensembl:ENSMUST00000103172(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|interpro:IPR029924|mint:Q9R0P5 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:DOTC+j1BapP+v6GCsY0vDXUKsPE10090 rogid:hqPae8VWEKvGPITqHtrSs78yI4M10090 intact-crc:DB6AD949374E760A|rigid:yn5f5573XfLLHHBsyrg6Yy9V0ww false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q99P81 uniprotkb:Q64176 intact:EBI-1184072|uniprotkb:Q8BKI5|ensembl:ENSMUSP00000031239 intact:EBI-1184020|ensembl:ENSMUSP00000034173 psi-mi:abcg3_mouse(display_long)|uniprotkb:Abcg3(gene name)|psi-mi:Abcg3(display_short) psi-mi:est1e_mouse(display_long)|uniprotkb:Ces1e(gene name)|psi-mi:Ces1e(display_short)|uniprotkb:Egasyn(gene name synonym)|uniprotkb:Es22(gene name synonym)|uniprotkb:Liver carboxylesterase 22(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184095|imex:IM-11844-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084515.2|ensembl:ENSMUSG00000029299(gene)|ensembl:ENSMUST00000031239(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR043926 refseq:NP_598421.1|ensembl:ENSMUSG00000061959(gene)|ensembl:ENSMUST00000034173(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005811"(lipid droplet)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0080030"(methyl indole-3-acetate esterase activity)|interpro:IPR002018(Carboxylesterase, type B)|interpro:IPR019819|interpro:IPR019826|interpro:IPR029058|mint:Q64176|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0047376"(all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:DOTC+j1BapP+v6GCsY0vDXUKsPE10090 rogid:6f0I6Js03v2bvRnsJUVWSUa3k6810090 intact-crc:DB6AD949374E760A|rigid:yn5f5573XfLLHHBsyrg6Yy9V0ww false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q99P81 uniprotkb:P26040 intact:EBI-1184072|uniprotkb:Q8BKI5|ensembl:ENSMUSP00000031239 intact:EBI-645505|uniprotkb:Q80ZT8|uniprotkb:Q9DCI1|ensembl:ENSMUSP00000063734 psi-mi:abcg3_mouse(display_long)|uniprotkb:Abcg3(gene name)|psi-mi:Abcg3(display_short) psi-mi:ezri_mouse(display_long)|uniprotkb:Vil2(gene name synonym)|uniprotkb:p81(gene name synonym)|uniprotkb:Cytovillin(gene name synonym)|uniprotkb:Villin-2(gene name synonym)|uniprotkb:Ezr(gene name)|psi-mi:Ezr(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184095|imex:IM-11844-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084515.2|ensembl:ENSMUSG00000029299(gene)|ensembl:ENSMUST00000031239(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR043926 refseq:NP_033536.2|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031623"(receptor internalization)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044297"(cell body)|go:"GO:0044393"(microspike)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097454"(Schwann cell microvillus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902896"(terminal web assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|interpro:IPR008954(Moesin)|mint:P26040|reactome:R-MMU-373752|reactome:R-MMU-437239|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|ensembl:ENSMUSG00000052397(gene)|ensembl:ENSMUST00000064234(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0001772"(immunological synapse)|go:"GO:0001931"(uropod)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:DOTC+j1BapP+v6GCsY0vDXUKsPE10090 rogid:PspmkV3JA32h1VGLkUgha3a59AA10090 intact-crc:DB6AD949374E760A|rigid:yn5f5573XfLLHHBsyrg6Yy9V0ww false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q99P81 uniprotkb:Q9CQW5 intact:EBI-1184072|uniprotkb:Q8BKI5|ensembl:ENSMUSP00000031239 intact:EBI-1184048|uniprotkb:Q9D800|uniprotkb:Q9D862|ensembl:ENSMUSP00000036598 psi-mi:abcg3_mouse(display_long)|uniprotkb:Abcg3(gene name)|psi-mi:Abcg3(display_short) psi-mi:leg2_mouse(display_long)|uniprotkb:Lgals2(gene name)|psi-mi:Lgals2(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184095|imex:IM-11844-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084515.2|ensembl:ENSMUSG00000029299(gene)|ensembl:ENSMUST00000031239(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR043926 refseq:NP_079898.2|ensembl:ENSMUSG00000043501(gene)|ensembl:ENSMUST00000044584(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016936"(galactoside binding)|go:"GO:0030246"(carbohydrate binding)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:DOTC+j1BapP+v6GCsY0vDXUKsPE10090 rogid:kcmtLimI9TH3VU09dz0w885YgrM10090 intact-crc:DB6AD949374E760A|rigid:yn5f5573XfLLHHBsyrg6Yy9V0ww false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q99P81 uniprotkb:Q8K419 intact:EBI-1184072|uniprotkb:Q8BKI5|ensembl:ENSMUSP00000031239 intact:EBI-1183873|uniprotkb:O88353|uniprotkb:Q91X74|ensembl:ENSMUSP00000066461 psi-mi:abcg3_mouse(display_long)|uniprotkb:Abcg3(gene name)|psi-mi:Abcg3(display_short) psi-mi:leg4_mouse(display_long)|uniprotkb:Lgals4(gene name)|psi-mi:Lgals4(display_short)|uniprotkb:Lactose-binding lectin 4(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184095|imex:IM-11844-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084515.2|ensembl:ENSMUSG00000029299(gene)|ensembl:ENSMUST00000031239(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR043926 refseq:NP_034836.1|ensembl:ENSMUSG00000053964(gene)|ensembl:ENSMUST00000066723(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0016936"(galactoside binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR015533(Galectin-4/6)|interpro:IPR044156|rcsb pdb:2DYC|rcsb pdb:3I8T psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:DOTC+j1BapP+v6GCsY0vDXUKsPE10090 rogid:CxB7/h34xwEn/pCyuUyG5RQSJsQ10090 intact-crc:DB6AD949374E760A|rigid:yn5f5573XfLLHHBsyrg6Yy9V0ww false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q99P81 uniprotkb:P70441 intact:EBI-1184072|uniprotkb:Q8BKI5|ensembl:ENSMUSP00000031239 intact:EBI-1184085|uniprotkb:Q8BYD8|ensembl:ENSMUSP00000021077 psi-mi:abcg3_mouse(display_long)|uniprotkb:Abcg3(gene name)|psi-mi:Abcg3(display_short) psi-mi:nhrf1_mouse(display_long)|uniprotkb:Slc9a3r1(gene name)|psi-mi:Slc9a3r1(display_short)|uniprotkb:Nherf(gene name synonym)|uniprotkb:Nherf1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184095|imex:IM-11844-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084515.2|ensembl:ENSMUSG00000029299(gene)|ensembl:ENSMUST00000031239(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR043926 refseq:NP_036160.1|ensembl:ENSMUSG00000020733(gene)|ensembl:ENSMUST00000021077(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0032420"(stereocilium)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|mint:P70441 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:DOTC+j1BapP+v6GCsY0vDXUKsPE10090 rogid:0Tz5KKGiYYEbcyP2lx4RrXUc76o10090 intact-crc:DB6AD949374E760A|rigid:yn5f5573XfLLHHBsyrg6Yy9V0ww false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q99P81 uniprotkb:P17742 intact:EBI-1184072|uniprotkb:Q8BKI5|ensembl:ENSMUSP00000031239 intact:EBI-1206043|uniprotkb:Q9CWJ5|uniprotkb:Q9R137|ensembl:ENSMUSP00000117987 psi-mi:abcg3_mouse(display_long)|uniprotkb:Abcg3(gene name)|psi-mi:Abcg3(display_short) psi-mi:ppia_mouse(display_long)|uniprotkb:Ppia(gene name)|psi-mi:Ppia(display_short)|uniprotkb:Cyclophilin A(gene name synonym)|uniprotkb:Cyclosporin A-binding protein(gene name synonym)|uniprotkb:SP18(gene name synonym)|uniprotkb:Rotamase A(gene name synonym) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184095|imex:IM-11844-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084515.2|ensembl:ENSMUSG00000029299(gene)|ensembl:ENSMUST00000031239(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR043926 refseq:NP_032933.1|reactome:R-MMU-210991|reactome:R-MMU-6798695|rcsb pdb:6FK1|ensembl:ENSMUSG00000071866(gene)|ensembl:ENSMUST00000132846(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0061944"(negative regulation of protein K48-linked ubiquitination)|go:"GO:0070527"(platelet aggregation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903901"(negative regulation of viral life cycle)|go:"GO:1904399"(heparan sulfate binding)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000|mint:P17742 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:DOTC+j1BapP+v6GCsY0vDXUKsPE10090 rogid:VwIoW2yfdaAEwZj6MfekFYqkZjw10090 intact-crc:DB6AD949374E760A|rigid:yn5f5573XfLLHHBsyrg6Yy9V0ww false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:Q99P81 uniprotkb:P62962 intact:EBI-1184072|uniprotkb:Q8BKI5|ensembl:ENSMUSP00000031239 intact:EBI-647096|uniprotkb:P10924|ensembl:ENSMUSP00000018437 psi-mi:abcg3_mouse(display_long)|uniprotkb:Abcg3(gene name)|psi-mi:Abcg3(display_short) psi-mi:prof1_mouse(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:Pfn1(gene name)|psi-mi:Pfn1(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184095|imex:IM-11844-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084515.2|ensembl:ENSMUSG00000029299(gene)|ensembl:ENSMUST00000031239(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR013525(ABC-2 type transporter)|interpro:IPR027417|interpro:IPR043926 refseq:NP_035202.1|dip:DIP-38075N|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050821"(protein stabilization)|go:"GO:0051054"(positive regulation of DNA metabolic process)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|mint:P62962|reactome:R-MMU-376176|reactome:R-MMU-4086400|reactome:R-MMU-5663220|ensembl:ENSMUSG00000018293(gene)|ensembl:ENSMUST00000018437(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol) psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:DOTC+j1BapP+v6GCsY0vDXUKsPE10090 rogid:nzOTw5XdywGrh+fA9AInGIexyGk10090 intact-crc:DB6AD949374E760A|rigid:yn5f5573XfLLHHBsyrg6Yy9V0ww false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P48036 uniprotkb:Q9CQW5 intact:EBI-1184119|uniprotkb:Q3U5Q1|uniprotkb:Q3U5X4|uniprotkb:Q3U8K1|uniprotkb:Q3UGV0|uniprotkb:Q99LA1|ensembl:ENSMUSP00000029266 intact:EBI-1184048|uniprotkb:Q9D800|uniprotkb:Q9D862|ensembl:ENSMUSP00000036598 psi-mi:anxa5_mouse(display_long)|uniprotkb:Anxa5(gene name)|psi-mi:Anxa5(display_short)|uniprotkb:Anx5(gene name synonym)|uniprotkb:Annexin-5(gene name synonym)|uniprotkb:Annexin V(gene name synonym)|uniprotkb:Lipocortin V(gene name synonym)|uniprotkb:Endonexin II(gene name synonym)|uniprotkb:Calphobindin I(gene name synonym)|uniprotkb:Placental anticoagulant protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein 4(gene name synonym)|uniprotkb:Thromboplastin inhibitor(gene name synonym)|uniprotkb:Vascular anticoagulant-alpha(gene name synonym)|uniprotkb:Anchorin CII(gene name synonym) psi-mi:leg2_mouse(display_long)|uniprotkb:Lgals2(gene name)|psi-mi:Lgals2(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184129|imex:IM-11844-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033803.1|go:"GO:1901317"(regulation of flagellated sperm motility)|go:"GO:1902721"(negative regulation of prolactin secretion)|interpro:IPR001464(Annexin)|interpro:IPR002392(Annexin, type V)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P48036|reactome:R-MMU-114608|go:"GO:0097211"(cellular response to gonadotropin-releasing hormone)|ensembl:ENSMUSG00000027712(gene)|ensembl:ENSMUST00000029266(transcript)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007596"(blood coagulation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010033"(response to organic substance)|go:"GO:0014704"(intercalated disc)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0030018"(Z disc)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072563"(endothelial microparticle) refseq:NP_079898.2|ensembl:ENSMUSG00000043501(gene)|ensembl:ENSMUST00000044584(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016936"(galactoside binding)|go:"GO:0030246"(carbohydrate binding)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:CJEThujZVYsg5/wpN8fAMdpY38U10090 rogid:kcmtLimI9TH3VU09dz0w885YgrM10090 intact-crc:CF969839B7DF5662|rigid:jtstSZn8jg6dZn7eIOkbT5TMpko false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P48036 uniprotkb:P62991 intact:EBI-1184119|uniprotkb:Q3U5Q1|uniprotkb:Q3U5X4|uniprotkb:Q3U8K1|uniprotkb:Q3UGV0|uniprotkb:Q99LA1|ensembl:ENSMUSP00000029266 intact:EBI-413074|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q62317|uniprotkb:Q64223|uniprotkb:Q8VCH1|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9CXY4|uniprotkb:Q9CZM0|uniprotkb:Q9D1R5|uniprotkb:Q9D8D9|uniprotkb:Q9ET23|uniprotkb:Q9ET24|uniprotkb:Q9Z0H9|dip:DIP-29742N psi-mi:anxa5_mouse(display_long)|uniprotkb:Anxa5(gene name)|psi-mi:Anxa5(display_short)|uniprotkb:Anx5(gene name synonym)|uniprotkb:Annexin-5(gene name synonym)|uniprotkb:Annexin V(gene name synonym)|uniprotkb:Lipocortin V(gene name synonym)|uniprotkb:Endonexin II(gene name synonym)|uniprotkb:Calphobindin I(gene name synonym)|uniprotkb:Placental anticoagulant protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein 4(gene name synonym)|uniprotkb:Thromboplastin inhibitor(gene name synonym)|uniprotkb:Vascular anticoagulant-alpha(gene name synonym)|uniprotkb:Anchorin CII(gene name synonym) psi-mi:ubiq_mouse(display_long)|uniprotkb:Rps27a(gene name)|psi-mi:Rps27a(display_short)|uniprotkb:Uba80(gene name synonym)|uniprotkb:Ubcep1(gene name synonym)|uniprotkb:Uba52(gene name)|psi-mi:Uba52(display_short)|uniprotkb:Ubcep2(gene name synonym)|uniprotkb:Ubb(gene name)|psi-mi:Ubb(display_short)|uniprotkb:Ubc(gene name)|psi-mi:Ubc(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184129|imex:IM-11844-20 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_033803.1|go:"GO:1901317"(regulation of flagellated sperm motility)|go:"GO:1902721"(negative regulation of prolactin secretion)|interpro:IPR001464(Annexin)|interpro:IPR002392(Annexin, type V)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P48036|reactome:R-MMU-114608|go:"GO:0097211"(cellular response to gonadotropin-releasing hormone)|ensembl:ENSMUSG00000027712(gene)|ensembl:ENSMUST00000029266(transcript)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007596"(blood coagulation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010033"(response to organic substance)|go:"GO:0014704"(intercalated disc)|go:"GO:0017046"(peptide hormone binding)|go:"GO:0030018"(Z disc)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030425"(dendrite)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072563"(endothelial microparticle) interpro:IPR000626(Ubiquitin)|refseq:NP_001029037.1|refseq:NP_035794.1|refseq:NP_075626.1|refseq:NP_077239.1|refseq:XP_001481004.1|go:"GO:0005515"(protein binding)|ensembl:ENSMUSG00000019505|ensembl:ENSMUSG00000020460|ensembl:ENSMUSG00000058838|ensembl:ENSMUSG00000068240|ensembl:ENSMUSG00000055553|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|ensembl:ENSMUSG00000008348|go:"GO:0005634"(nucleus)|rcsb pdb:2ZNV|ipi:IPI00750889|refseq:XP_889611.1|rcsb pdb:3A1Q|rcsb pdb:3A9J|rcsb pdb:3A9K psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:CJEThujZVYsg5/wpN8fAMdpY38U10090 rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM10090 intact-crc:CF969839B7DF5662|rigid:jtstSZn8jg6dZn7eIOkbT5TMpko false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P51162 uniprotkb:Q9CQW5 intact:EBI-1184146|uniprotkb:Q5SRT9|ensembl:ENSMUSP00000020672 intact:EBI-1184048|uniprotkb:Q9D800|uniprotkb:Q9D862|ensembl:ENSMUSP00000036598 psi-mi:fabp6_mouse(display_long)|uniprotkb:Fabp6(gene name)|psi-mi:Fabp6(display_short)|uniprotkb:Illbp(gene name synonym)|uniprotkb:Fatty acid-binding protein 6(gene name synonym)|uniprotkb:Ileal lipid-binding protein(gene name synonym) psi-mi:leg2_mouse(display_long)|uniprotkb:Lgals2(gene name)|psi-mi:Lgals2(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184158|imex:IM-11844-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032401.1|ensembl:ENSMUSG00000020405(gene)|ensembl:ENSMUST00000020672(transcript)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0006869"(lipid transport)|go:"GO:0008206"(bile acid metabolic process)|go:"GO:0016020"(membrane)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR012674(Calycin)|interpro:IPR031259|reactome:R-MMU-159418|reactome:R-MMU-163560 refseq:NP_079898.2|ensembl:ENSMUSG00000043501(gene)|ensembl:ENSMUST00000044584(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016936"(galactoside binding)|go:"GO:0030246"(carbohydrate binding)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supplementary Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:ocUiWsOvB2MJKlq7rIAaFu6jpUA10090 rogid:kcmtLimI9TH3VU09dz0w885YgrM10090 intact-crc:F64BA28669F21018|rigid:b65wlCXyX/24cTvsXcf/ZA9qIPY false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P97449 intact:EBI-1205176 intact:EBI-1183379|uniprotkb:Q91YH8|uniprotkb:Q99K63|ensembl:ENSMUSP00000035943|ensembl:ENSMUSP00000103015 - psi-mi:ampn_mouse(display_long)|uniprotkb:Anpep(gene name)|psi-mi:Anpep(display_short)|uniprotkb:Lap1(gene name synonym)|uniprotkb:Lap-1(gene name synonym)|uniprotkb:Alanyl aminopeptidase(gene name synonym)|uniprotkb:Microsomal aminopeptidase(gene name synonym)|uniprotkb:Aminopeptidase M(gene name synonym)|uniprotkb:Membrane protein p161(gene name synonym) psi-mi:pep_wgghwlgdntaawdql(display_short)|psi-mi:EBI-1205176(display_long) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1204980|imex:IM-11844-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) refseq:NP_032512.2|refseq:XP_006540741.1|ensembl:ENSMUSG00000039062(gene)|ensembl:ENSMUST00000049004(transcript)|ensembl:ENSMUST00000107392(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|mint:P97449|reactome:R-MMU-6798695 - psi-mi:"MI:0469"(intact) - no-uniprot-update:An amino acid sequence which is not represented in UniProt figure legend:Table 1. Supporting Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:jC8fCyra4ze3wg0+0cCJ38HnVhk10090 rogid:pT7h45S0/AnPhsTN6I7eJBfJue810090 intact-crc:8BA37282824A93A2|rigid:qxS2tex35BJahYRNoVuxcc+V2p4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P97449 uniprotkb:Q8K0P6 intact:EBI-1183379|uniprotkb:Q91YH8|uniprotkb:Q99K63|ensembl:ENSMUSP00000035943|ensembl:ENSMUSP00000103015 intact:EBI-1183390 psi-mi:ampn_mouse(display_long)|uniprotkb:Anpep(gene name)|psi-mi:Anpep(display_short)|uniprotkb:Lap1(gene name synonym)|uniprotkb:Lap-1(gene name synonym)|uniprotkb:Alanyl aminopeptidase(gene name synonym)|uniprotkb:Microsomal aminopeptidase(gene name synonym)|uniprotkb:Aminopeptidase M(gene name synonym)|uniprotkb:Membrane protein p161(gene name synonym) psi-mi:q8k0p6_mouse(display_long)|uniprotkb:Fcgbp(gene name)|psi-mi:Fcgbp(display_short) psi-mi:"MI:0276"(blue native page) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1204980|imex:IM-11844-22 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032512.2|refseq:XP_006540741.1|ensembl:ENSMUSG00000039062(gene)|ensembl:ENSMUST00000049004(transcript)|ensembl:ENSMUST00000107392(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|mint:P97449|reactome:R-MMU-6798695 interpro:IPR036084|interpro:IPR002919(Protease inhibitor I8, cysteine-rich trypsin inhibitor-like)|interpro:IPR014853(Region of unknown function DUF1787)|interpro:IPR001846(von Willebrand factor, type D)|interpro:IPR001007(von Willebrand factor, type C)|go:"GO:0005615"(extracellular space)|go:"GO:0031012"(extracellular matrix)|interpro:IPR025615 psi-mi:"MI:0469"(intact) - - figure legend:Table 1. Supporting Information.|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:jC8fCyra4ze3wg0+0cCJ38HnVhk10090 rogid:q+rWbyUAC2UcZr8tt5kE11i+iic10090 intact-crc:8BA37282824A93A2|rigid:qxS2tex35BJahYRNoVuxcc+V2p4 false - - - - psi-mi:"MI:0082"(peptide massfingerprinting) psi-mi:"MI:0082"(peptide massfingerprinting) uniprotkb:P97449 uniprotkb:Q52JJ6 intact:EBI-1183379|uniprotkb:Q91YH8|uniprotkb:Q99K63|ensembl:ENSMUSP00000035943|ensembl:ENSMUSP00000103015 intact:EBI-1183443 psi-mi:ampn_mouse(display_long)|uniprotkb:Anpep(gene name)|psi-mi:Anpep(display_short)|uniprotkb:Lap1(gene name synonym)|uniprotkb:Lap-1(gene name synonym)|uniprotkb:Alanyl aminopeptidase(gene name synonym)|uniprotkb:Microsomal aminopeptidase(gene name synonym)|uniprotkb:Aminopeptidase M(gene name synonym)|uniprotkb:Membrane protein p161(gene name synonym) psi-mi:q52jj6_mouse(display_long)|uniprotkb:Enpep(gene name)|psi-mi:Enpep(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184185|imex:IM-11844-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032512.2|refseq:XP_006540741.1|ensembl:ENSMUSG00000039062(gene)|ensembl:ENSMUST00000049004(transcript)|ensembl:ENSMUST00000107392(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|mint:P97449|reactome:R-MMU-6798695 refseq:NP_031960.1|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR033508|go:"GO:0003081"(regulation of systemic arterial blood pressure by renin-angiotensin)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0070006"(metalloaminopeptidase activity)|interpro:IPR024571|interpro:IPR034016|interpro:IPR027268|interpro:IPR042097 psi-mi:"MI:0469"(intact) - - figure legend:3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:jC8fCyra4ze3wg0+0cCJ38HnVhk10090 rogid:bDro3Qmjuqod515sHYhg69YNhmA10090 intact-crc:754D9C3AF5809BA5|rigid:ZRta+DFrY3f/FQQ+TOCVvDykBMs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P97449 intact:EBI-1205138 intact:EBI-1183379|uniprotkb:Q91YH8|uniprotkb:Q99K63|ensembl:ENSMUSP00000035943|ensembl:ENSMUSP00000103015 - psi-mi:ampn_mouse(display_long)|uniprotkb:Anpep(gene name)|psi-mi:Anpep(display_short)|uniprotkb:Lap1(gene name synonym)|uniprotkb:Lap-1(gene name synonym)|uniprotkb:Alanyl aminopeptidase(gene name synonym)|uniprotkb:Microsomal aminopeptidase(gene name synonym)|uniprotkb:Aminopeptidase M(gene name synonym)|uniprotkb:Membrane protein p161(gene name synonym) psi-mi:pep_ytllpfytlyfyr(display_short)|psi-mi:EBI-1205138(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Babusiak et al. (2007) imex:IM-11844|pubmed:17205597 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-1184185|imex:IM-11844-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0327"(peptide) refseq:NP_032512.2|refseq:XP_006540741.1|ensembl:ENSMUSG00000039062(gene)|ensembl:ENSMUST00000049004(transcript)|ensembl:ENSMUST00000107392(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031526"(brush border membrane)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|mint:P97449|reactome:R-MMU-6798695 - psi-mi:"MI:0469"(intact) - no-uniprot-update:An amino acid sequence which is not represented in UniProt figure legend:3|dataset:Apoptosis - Interactions involving proteins with a function related to apoptosis|dataset:Synapse - Interactions of proteins with an established role in the presynapse.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-intestinal_epitheliu)|taxid:10090(Mouse intestinal epithelial cells) - 2007/01/10 2014/10/16 rogid:jC8fCyra4ze3wg0+0cCJ38HnVhk10090 rogid:AzFc4Fl2xJKsaBcGYFbVw59Zhv410090 intact-crc:754D9C3AF5809BA5|rigid:ZRta+DFrY3f/FQQ+TOCVvDykBMs false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)