#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q64702 uniprotkb:P03772 intact:EBI-2552433|ensembl:ENSMUSP00000026858|uniprotkb:Q78EG6|uniprotkb:Q3UVA3|uniprotkb:Q6PEP6|uniprotkb:Q9CVU6|uniprotkb:Q80UT6|uniprotkb:Q9CVR6|uniprotkb:Q8R0I5 intact:EBI-4478820 psi-mi:plk4_mouse(display_long)|uniprotkb:Plk4(gene name)|psi-mi:Plk4(display_short)|uniprotkb:Sak(gene name synonym)|uniprotkb:Stk18(gene name synonym)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym) psi-mi:pp_lambd(display_long) psi-mi:"MI:0434"(phosphatase assay) Leung et al. (2007) pubmed:17174311|imex:IM-11101|mint:MINT-5219473 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10710(lambd)|taxid:10710(Enterobacteria phage lambda) psi-mi:"MI:0203"(dephosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7181949|mint:MINT-4053818|imex:IM-11101-2 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775261.2|ensembl:ENSMUSG00000025758(gene)|ensembl:ENSMUST00000026858(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:Q64702|rcsb pdb:1MBY|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|refseq:NP_035625.2|dip:DIP-42244N|mint:MINT-4053819(identity) refseq:NP_040641.1|mint:P03772|dip:DIP-44028N|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|rcsb pdb:1G5B|mint:MINT-4053820(identity) - - - figure legend:F1A|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/01/22 2014/10/16 rogid:L1/nN7/3X379zeA2OE3rfje+Cvc10090 rogid:IC53qKTTD+P3le+ITRfvcRjQGrY10710 intact-crc:4B9F08D2D5CE8087|rigid:i/eR11JSAQLSNQhRzaLUbjv0oJg false glutathione s tranferase tag:?-?(MINT-4053824)|mutation disrupting interaction:154-154(MINT-4053831)|binding-associated region:1-390(MINT-4053828) - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P03772 uniprotkb:Q64702 intact:EBI-4478820 intact:EBI-2552433|ensembl:ENSMUSP00000026858|uniprotkb:Q78EG6|uniprotkb:Q3UVA3|uniprotkb:Q6PEP6|uniprotkb:Q9CVU6|uniprotkb:Q80UT6|uniprotkb:Q9CVR6|uniprotkb:Q8R0I5 psi-mi:pp_lambd(display_long) psi-mi:plk4_mouse(display_long)|uniprotkb:Plk4(gene name)|psi-mi:Plk4(display_short)|uniprotkb:Sak(gene name synonym)|uniprotkb:Stk18(gene name synonym)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym) psi-mi:"MI:0434"(phosphatase assay) Leung et al. (2007) pubmed:17174311|imex:IM-11101|mint:MINT-5219473 taxid:10710(lambd)|taxid:10710(Enterobacteria phage lambda) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0203"(dephosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7181975|mint:MINT-4053838|imex:IM-11101-3 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_040641.1|mint:P03772|dip:DIP-44028N|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|rcsb pdb:1G5B|mint:MINT-4053850(identity) refseq:NP_775261.2|ensembl:ENSMUSG00000025758(gene)|ensembl:ENSMUST00000026858(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:Q64702|rcsb pdb:1MBY|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|refseq:NP_035625.2|dip:DIP-42244N|mint:MINT-4053839(identity) - - - figure legend:F1A|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/01/22 2014/10/16 rogid:IC53qKTTD+P3le+ITRfvcRjQGrY10710 rogid:L1/nN7/3X379zeA2OE3rfje+Cvc10090 intact-crc:90D009435013578A|rigid:i/eR11JSAQLSNQhRzaLUbjv0oJg false - binding-associated region:1-390(MINT-4053843) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P02686-1 uniprotkb:Q64702 intact:EBI-7056012|intact:MINT-1792635|ensembl:ENSP00000348273|ensembl:ENSP00000462223 intact:EBI-2552433|ensembl:ENSMUSP00000026858|uniprotkb:Q78EG6|uniprotkb:Q3UVA3|uniprotkb:Q6PEP6|uniprotkb:Q9CVU6|uniprotkb:Q80UT6|uniprotkb:Q9CVR6|uniprotkb:Q8R0I5 psi-mi:p02686-1(display_long)|uniprotkb:MBP(gene name)|psi-mi:MBP(display_short)|uniprotkb:Myelin A1 protein(gene name synonym)|uniprotkb:Myelin membrane encephalitogenic protein(gene name synonym)|uniprotkb:Golli-MBP1(isoform synonym)|uniprotkb:HOG7(isoform synonym) psi-mi:plk4_mouse(display_long)|uniprotkb:Plk4(gene name)|psi-mi:Plk4(display_short)|uniprotkb:Sak(gene name synonym)|uniprotkb:Stk18(gene name synonym)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Leung et al. (2007) pubmed:17174311|imex:IM-11101|mint:MINT-5219473 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7182003|mint:MINT-4053856|imex:IM-11101-4 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-947410(isoform-parent)|ensembl:ENSG00000197971(gene)|ensembl:ENST00000355994(transcript)|ensembl:ENST00000580402(transcript)|mint:MINT-4053857(identity) refseq:NP_775261.2|ensembl:ENSMUSG00000025758(gene)|ensembl:ENSMUST00000026858(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:Q64702|rcsb pdb:1MBY|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|refseq:NP_035625.2|dip:DIP-42244N|mint:MINT-4053860(identity) - comment:mint - figure legend:F1B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/01/22 2014/10/16 rogid:ebDCekUqLVlpi0vmYj/WZjha+AQ9606 rogid:L1/nN7/3X379zeA2OE3rfje+Cvc10090 intact-crc:FE22CBEBB21335B0|rigid:MaCu+P15MfQMCCLZQn2JJHFKwp8 false - glutathione s tranferase tag:?-?(MINT-4053867)|mutation disrupting interaction:154-154(MINT-4053869)|binding-associated region:1-390(MINT-4053862) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P02686-1 uniprotkb:Q64702 intact:EBI-7056012|intact:MINT-1792635|ensembl:ENSP00000348273|ensembl:ENSP00000462223 intact:EBI-2552433|ensembl:ENSMUSP00000026858|uniprotkb:Q78EG6|uniprotkb:Q3UVA3|uniprotkb:Q6PEP6|uniprotkb:Q9CVU6|uniprotkb:Q80UT6|uniprotkb:Q9CVR6|uniprotkb:Q8R0I5 psi-mi:p02686-1(display_long)|uniprotkb:MBP(gene name)|psi-mi:MBP(display_short)|uniprotkb:Myelin A1 protein(gene name synonym)|uniprotkb:Myelin membrane encephalitogenic protein(gene name synonym)|uniprotkb:Golli-MBP1(isoform synonym)|uniprotkb:HOG7(isoform synonym) psi-mi:plk4_mouse(display_long)|uniprotkb:Plk4(gene name)|psi-mi:Plk4(display_short)|uniprotkb:Sak(gene name synonym)|uniprotkb:Stk18(gene name synonym)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Leung et al. (2007) pubmed:17174311|imex:IM-11101|mint:MINT-5219473 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7182049|mint:MINT-4053877|imex:IM-11101-5 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-947410(isoform-parent)|ensembl:ENSG00000197971(gene)|ensembl:ENST00000355994(transcript)|ensembl:ENST00000580402(transcript)|mint:MINT-4053878(identity) refseq:NP_775261.2|ensembl:ENSMUSG00000025758(gene)|ensembl:ENSMUST00000026858(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:Q64702|rcsb pdb:1MBY|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|refseq:NP_035625.2|dip:DIP-42244N|mint:MINT-4053881(identity) - comment:mint - figure legend:F1B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/01/22 2014/10/16 rogid:ebDCekUqLVlpi0vmYj/WZjha+AQ9606 rogid:L1/nN7/3X379zeA2OE3rfje+Cvc10090 intact-crc:73DA10698B07D6BA|rigid:MaCu+P15MfQMCCLZQn2JJHFKwp8 false - binding-associated region:1-390(MINT-4053887) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64702 uniprotkb:Q64702 intact:EBI-2552433|ensembl:ENSMUSP00000026858|uniprotkb:Q78EG6|uniprotkb:Q3UVA3|uniprotkb:Q6PEP6|uniprotkb:Q9CVU6|uniprotkb:Q80UT6|uniprotkb:Q9CVR6|uniprotkb:Q8R0I5 intact:EBI-2552433|ensembl:ENSMUSP00000026858|uniprotkb:Q78EG6|uniprotkb:Q3UVA3|uniprotkb:Q6PEP6|uniprotkb:Q9CVU6|uniprotkb:Q80UT6|uniprotkb:Q9CVR6|uniprotkb:Q8R0I5 psi-mi:plk4_mouse(display_long)|uniprotkb:Plk4(gene name)|psi-mi:Plk4(display_short)|uniprotkb:Sak(gene name synonym)|uniprotkb:Stk18(gene name synonym)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym) psi-mi:plk4_mouse(display_long)|uniprotkb:Plk4(gene name)|psi-mi:Plk4(display_short)|uniprotkb:Sak(gene name synonym)|uniprotkb:Stk18(gene name synonym)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Leung et al. (2007) pubmed:17174311|imex:IM-11101|mint:MINT-5219473 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7182121|mint:MINT-4053924|imex:IM-11101-7 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0503"(self) psi-mi:"MI:0503"(self) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775261.2|ensembl:ENSMUSG00000025758(gene)|ensembl:ENSMUST00000026858(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:Q64702|rcsb pdb:1MBY|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|refseq:NP_035625.2|dip:DIP-42244N|mint:MINT-4053925(identity) refseq:NP_775261.2|ensembl:ENSMUSG00000025758(gene)|ensembl:ENSMUST00000026858(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:Q64702|rcsb pdb:1MBY|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|refseq:NP_035625.2|dip:DIP-42244N|mint:MINT-4053936(identity) - - - figure legend:F1B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/01/22 2014/10/16 rogid:L1/nN7/3X379zeA2OE3rfje+Cvc10090 rogid:L1/nN7/3X379zeA2OE3rfje+Cvc10090 intact-crc:E21E9790A914C644|rigid:4k9WoeJ/RWq3NXE31vPxg5Ba9L4 false binding-associated region:1-390(MINT-4053929) binding-associated region:1-390(MINT-4053942) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64702 uniprotkb:Q64702 intact:EBI-2552433|ensembl:ENSMUSP00000026858|uniprotkb:Q78EG6|uniprotkb:Q3UVA3|uniprotkb:Q6PEP6|uniprotkb:Q9CVU6|uniprotkb:Q80UT6|uniprotkb:Q9CVR6|uniprotkb:Q8R0I5 intact:EBI-2552433|ensembl:ENSMUSP00000026858|uniprotkb:Q78EG6|uniprotkb:Q3UVA3|uniprotkb:Q6PEP6|uniprotkb:Q9CVU6|uniprotkb:Q80UT6|uniprotkb:Q9CVR6|uniprotkb:Q8R0I5 psi-mi:plk4_mouse(display_long)|uniprotkb:Plk4(gene name)|psi-mi:Plk4(display_short)|uniprotkb:Sak(gene name synonym)|uniprotkb:Stk18(gene name synonym)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym) psi-mi:plk4_mouse(display_long)|uniprotkb:Plk4(gene name)|psi-mi:Plk4(display_short)|uniprotkb:Sak(gene name synonym)|uniprotkb:Stk18(gene name synonym)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym) psi-mi:"MI:0424"(protein kinase assay) Leung et al. (2007) pubmed:17174311|imex:IM-11101|mint:MINT-5219473 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7182067|mint:MINT-4053898|imex:IM-11101-6 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0503"(self) psi-mi:"MI:0503"(self) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775261.2|ensembl:ENSMUSG00000025758(gene)|ensembl:ENSMUST00000026858(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:Q64702|rcsb pdb:1MBY|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|refseq:NP_035625.2|dip:DIP-42244N|mint:MINT-4053899(identity) refseq:NP_775261.2|ensembl:ENSMUSG00000025758(gene)|ensembl:ENSMUST00000026858(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:Q64702|rcsb pdb:1MBY|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|refseq:NP_035625.2|dip:DIP-42244N|mint:MINT-4053905(identity) - - - figure legend:F1B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/01/22 2014/10/16 rogid:L1/nN7/3X379zeA2OE3rfje+Cvc10090 rogid:L1/nN7/3X379zeA2OE3rfje+Cvc10090 intact-crc:5407B044FB99E7F9|rigid:4k9WoeJ/RWq3NXE31vPxg5Ba9L4 false mutation disrupting interaction:154-154(MINT-4053911)|binding-associated region:1-390(MINT-4053901)|glutathione s tranferase tag:?-?(MINT-4053909) mutation disrupting interaction:154-154(MINT-4053920)|binding-associated region:1-390(MINT-4053917)|glutathione s tranferase tag:?-?(MINT-4053915) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64702 uniprotkb:Q64702 intact:EBI-2552433|ensembl:ENSMUSP00000026858|uniprotkb:Q78EG6|uniprotkb:Q3UVA3|uniprotkb:Q6PEP6|uniprotkb:Q9CVU6|uniprotkb:Q80UT6|uniprotkb:Q9CVR6|uniprotkb:Q8R0I5 intact:EBI-2552433|ensembl:ENSMUSP00000026858|uniprotkb:Q78EG6|uniprotkb:Q3UVA3|uniprotkb:Q6PEP6|uniprotkb:Q9CVU6|uniprotkb:Q80UT6|uniprotkb:Q9CVR6|uniprotkb:Q8R0I5 psi-mi:plk4_mouse(display_long)|uniprotkb:Plk4(gene name)|psi-mi:Plk4(display_short)|uniprotkb:Sak(gene name synonym)|uniprotkb:Stk18(gene name synonym)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym) psi-mi:plk4_mouse(display_long)|uniprotkb:Plk4(gene name)|psi-mi:Plk4(display_short)|uniprotkb:Sak(gene name synonym)|uniprotkb:Stk18(gene name synonym)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Leung et al. (2007) pubmed:17174311|imex:IM-11101|mint:MINT-5219473 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-7182154|mint:MINT-4053950|imex:IM-11101-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775261.2|ensembl:ENSMUSG00000025758(gene)|ensembl:ENSMUST00000026858(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:Q64702|rcsb pdb:1MBY|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|refseq:NP_035625.2|dip:DIP-42244N|mint:MINT-4053951(identity) refseq:NP_775261.2|ensembl:ENSMUSG00000025758(gene)|ensembl:ENSMUST00000026858(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:Q64702|rcsb pdb:1MBY|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|refseq:NP_035625.2|dip:DIP-42244N|mint:MINT-4053957(identity) - - - figure legend:SF1A|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2007/01/22 2014/10/16 rogid:L1/nN7/3X379zeA2OE3rfje+Cvc10090 rogid:L1/nN7/3X379zeA2OE3rfje+Cvc10090 intact-crc:64FC03B607C1253E|rigid:4k9WoeJ/RWq3NXE31vPxg5Ba9L4 false binding-associated region:525-796(MINT-4053953)|flag tag:?-?(MINT-4053964) binding-associated region:1-595(MINT-4053959)|myc tag:?-?(MINT-4053969) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64702 uniprotkb:Q64702 intact:EBI-2552433|ensembl:ENSMUSP00000026858|uniprotkb:Q78EG6|uniprotkb:Q3UVA3|uniprotkb:Q6PEP6|uniprotkb:Q9CVU6|uniprotkb:Q80UT6|uniprotkb:Q9CVR6|uniprotkb:Q8R0I5 intact:EBI-2552433|ensembl:ENSMUSP00000026858|uniprotkb:Q78EG6|uniprotkb:Q3UVA3|uniprotkb:Q6PEP6|uniprotkb:Q9CVU6|uniprotkb:Q80UT6|uniprotkb:Q9CVR6|uniprotkb:Q8R0I5 psi-mi:plk4_mouse(display_long)|uniprotkb:Plk4(gene name)|psi-mi:Plk4(display_short)|uniprotkb:Sak(gene name synonym)|uniprotkb:Stk18(gene name synonym)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym) psi-mi:plk4_mouse(display_long)|uniprotkb:Plk4(gene name)|psi-mi:Plk4(display_short)|uniprotkb:Sak(gene name synonym)|uniprotkb:Stk18(gene name synonym)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym) psi-mi:"MI:0096"(pull down) Leung et al. (2007) pubmed:17174311|imex:IM-11101|mint:MINT-5219473 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-7182194|mint:MINT-4053978|imex:IM-11101-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775261.2|ensembl:ENSMUSG00000025758(gene)|ensembl:ENSMUST00000026858(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:Q64702|rcsb pdb:1MBY|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|refseq:NP_035625.2|dip:DIP-42244N|mint:MINT-4053979(identity) refseq:NP_775261.2|ensembl:ENSMUSG00000025758(gene)|ensembl:ENSMUST00000026858(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:Q64702|rcsb pdb:1MBY|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|refseq:NP_035625.2|dip:DIP-42244N|mint:MINT-4053988(identity) - - - figure legend:SF1B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/01/22 2014/10/16 rogid:L1/nN7/3X379zeA2OE3rfje+Cvc10090 rogid:L1/nN7/3X379zeA2OE3rfje+Cvc10090 intact-crc:56578F8333929D01|rigid:4k9WoeJ/RWq3NXE31vPxg5Ba9L4 false binding-associated region:1-390(MINT-4053984)|glutathione s tranferase tag:?-?(MINT-4054051) binding-associated region:525-796(MINT-4053990)|his tag:?-?(MINT-4053995) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q64702 uniprotkb:Q8WWL7 intact:EBI-2552433|ensembl:ENSMUSP00000026858|uniprotkb:Q78EG6|uniprotkb:Q3UVA3|uniprotkb:Q6PEP6|uniprotkb:Q9CVU6|uniprotkb:Q80UT6|uniprotkb:Q9CVR6|uniprotkb:Q8R0I5 intact:EBI-767764|uniprotkb:Q96SB5|uniprotkb:Q96SB6|uniprotkb:Q96SB7|uniprotkb:Q9NT38|uniprotkb:B1AQI6|uniprotkb:B1AQI5|ensembl:ENSP00000365210|ensembl:ENSP00000276014 psi-mi:plk4_mouse(display_long)|uniprotkb:Plk4(gene name)|psi-mi:Plk4(display_short)|uniprotkb:Sak(gene name synonym)|uniprotkb:Stk18(gene name synonym)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym) psi-mi:ccnb3_human(display_long)|uniprotkb:CCNB3(gene name)|psi-mi:CCNB3(display_short)|uniprotkb:CYCB3(gene name synonym) psi-mi:"MI:0081"(peptide array) Leung et al. (2007) pubmed:17174311|imex:IM-11101|mint:MINT-5219473 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7182234|mint:MINT-4054055|imex:IM-11101-9 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775261.2|ensembl:ENSMUSG00000025758(gene)|ensembl:ENSMUST00000026858(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:Q64702|rcsb pdb:1MBY|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|refseq:NP_035625.2|dip:DIP-42244N|mint:MINT-4054056(identity) refseq:NP_149020.2|refseq:NP_391990.1|refseq:XP_016885407.1|ensembl:ENSG00000147082(gene)|ensembl:ENST00000276014(transcript)|ensembl:ENST00000376042(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015452(G2/mitotic-specific cyclin B3)|interpro:IPR036915|interpro:IPR039361|mint:Q8WWL7|mint:MINT-4054064(identity) - - - figure legend:F2D|figure legend:STS1|figure legend:STS2|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/01/22 2014/10/16 rogid:L1/nN7/3X379zeA2OE3rfje+Cvc10090 rogid:DWq1aIaKl0+TykoAniMvm2EXdmY9606 intact-crc:BA9C45B5BF4D97B8|rigid:kBjDFTvtYEOoEo49ph/x57oC/gI false mutation disrupting interaction:154-154(MINT-4054074)|binding-associated region:1-390(MINT-4054060) binding-associated region:287-289(MINT-4054068)|mutation disrupting interaction:291-291(MINT-4054083) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q64702 uniprotkb:Q8WWL7 intact:EBI-2552433|ensembl:ENSMUSP00000026858|uniprotkb:Q78EG6|uniprotkb:Q3UVA3|uniprotkb:Q6PEP6|uniprotkb:Q9CVU6|uniprotkb:Q80UT6|uniprotkb:Q9CVR6|uniprotkb:Q8R0I5 intact:EBI-767764|uniprotkb:Q96SB5|uniprotkb:Q96SB6|uniprotkb:Q96SB7|uniprotkb:Q9NT38|uniprotkb:B1AQI6|uniprotkb:B1AQI5|ensembl:ENSP00000365210|ensembl:ENSP00000276014 psi-mi:plk4_mouse(display_long)|uniprotkb:Plk4(gene name)|psi-mi:Plk4(display_short)|uniprotkb:Sak(gene name synonym)|uniprotkb:Stk18(gene name synonym)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym) psi-mi:ccnb3_human(display_long)|uniprotkb:CCNB3(gene name)|psi-mi:CCNB3(display_short)|uniprotkb:CYCB3(gene name synonym) psi-mi:"MI:0081"(peptide array) Leung et al. (2007) pubmed:17174311|imex:IM-11101|mint:MINT-5219473 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7182285|mint:MINT-4054096|imex:IM-11101-10 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775261.2|ensembl:ENSMUSG00000025758(gene)|ensembl:ENSMUST00000026858(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:Q64702|rcsb pdb:1MBY|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|refseq:NP_035625.2|dip:DIP-42244N|mint:MINT-4054110(identity) refseq:NP_149020.2|refseq:NP_391990.1|refseq:XP_016885407.1|ensembl:ENSG00000147082(gene)|ensembl:ENST00000276014(transcript)|ensembl:ENST00000376042(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015452(G2/mitotic-specific cyclin B3)|interpro:IPR036915|interpro:IPR039361|mint:Q8WWL7|mint:MINT-4054097(identity) - - - figure legend:F2D|figure legend:STS1|figure legend:STS2|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/01/22 2014/10/16 rogid:L1/nN7/3X379zeA2OE3rfje+Cvc10090 rogid:DWq1aIaKl0+TykoAniMvm2EXdmY9606 intact-crc:8DB028E07E45EEC5|rigid:kBjDFTvtYEOoEo49ph/x57oC/gI false binding-associated region:1-390(MINT-4054114)|mutation disrupting interaction:154-154(MINT-4054111) mutation disrupting interaction:292-292(MINT-4054098)|binding-associated region:287-289(MINT-4054104) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q64702 uniprotkb:Q8WWL7 intact:EBI-2552433|ensembl:ENSMUSP00000026858|uniprotkb:Q78EG6|uniprotkb:Q3UVA3|uniprotkb:Q6PEP6|uniprotkb:Q9CVU6|uniprotkb:Q80UT6|uniprotkb:Q9CVR6|uniprotkb:Q8R0I5 intact:EBI-767764|uniprotkb:Q96SB5|uniprotkb:Q96SB6|uniprotkb:Q96SB7|uniprotkb:Q9NT38|uniprotkb:B1AQI6|uniprotkb:B1AQI5|ensembl:ENSP00000365210|ensembl:ENSP00000276014 psi-mi:plk4_mouse(display_long)|uniprotkb:Plk4(gene name)|psi-mi:Plk4(display_short)|uniprotkb:Sak(gene name synonym)|uniprotkb:Stk18(gene name synonym)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym) psi-mi:ccnb3_human(display_long)|uniprotkb:CCNB3(gene name)|psi-mi:CCNB3(display_short)|uniprotkb:CYCB3(gene name synonym) psi-mi:"MI:0081"(peptide array) Leung et al. (2007) pubmed:17174311|imex:IM-11101|mint:MINT-5219473 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7182321|mint:MINT-4054125|imex:IM-11101-11 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_775261.2|ensembl:ENSMUSG00000025758(gene)|ensembl:ENSMUST00000026858(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:Q64702|rcsb pdb:1MBY|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|refseq:NP_035625.2|dip:DIP-42244N|mint:MINT-4054126(identity) refseq:NP_149020.2|refseq:NP_391990.1|refseq:XP_016885407.1|ensembl:ENSG00000147082(gene)|ensembl:ENST00000276014(transcript)|ensembl:ENST00000376042(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015452(G2/mitotic-specific cyclin B3)|interpro:IPR036915|interpro:IPR039361|mint:Q8WWL7|mint:MINT-4054135(identity) - - - figure legend:F2D|figure legend:STS1|figure legend:STS2|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/01/22 2014/10/16 rogid:L1/nN7/3X379zeA2OE3rfje+Cvc10090 rogid:DWq1aIaKl0+TykoAniMvm2EXdmY9606 intact-crc:35C10FCE07857250|rigid:kBjDFTvtYEOoEo49ph/x57oC/gI false binding-associated region:1-390(MINT-4054128)|mutation disrupting interaction:154-154(MINT-4054131) mutation disrupting interaction:293-293(MINT-4054141)|binding-associated region:287-289(MINT-4054137) - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0083"(peptide synthesis) uniprotkb:Q8WWL7 uniprotkb:Q64702 intact:EBI-767764|uniprotkb:Q96SB5|uniprotkb:Q96SB6|uniprotkb:Q96SB7|uniprotkb:Q9NT38|uniprotkb:B1AQI6|uniprotkb:B1AQI5|ensembl:ENSP00000365210|ensembl:ENSP00000276014 intact:EBI-2552433|ensembl:ENSMUSP00000026858|uniprotkb:Q78EG6|uniprotkb:Q3UVA3|uniprotkb:Q6PEP6|uniprotkb:Q9CVU6|uniprotkb:Q80UT6|uniprotkb:Q9CVR6|uniprotkb:Q8R0I5 psi-mi:ccnb3_human(display_long)|uniprotkb:CCNB3(gene name)|psi-mi:CCNB3(display_short)|uniprotkb:CYCB3(gene name synonym) psi-mi:plk4_mouse(display_long)|uniprotkb:Plk4(gene name)|psi-mi:Plk4(display_short)|uniprotkb:Sak(gene name synonym)|uniprotkb:Stk18(gene name synonym)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym) psi-mi:"MI:0081"(peptide array) Leung et al. (2007) pubmed:17174311|imex:IM-11101|mint:MINT-5219473 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0217"(phosphorylation reaction) psi-mi:"MI:0471"(MINT) intact:EBI-7182377|mint:MINT-4054157|imex:IM-11101-8 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_149020.2|refseq:NP_391990.1|refseq:XP_016885407.1|ensembl:ENSG00000147082(gene)|ensembl:ENST00000276014(transcript)|ensembl:ENST00000376042(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0010389"(regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015452(G2/mitotic-specific cyclin B3)|interpro:IPR036915|interpro:IPR039361|mint:Q8WWL7|mint:MINT-4054158(identity) refseq:NP_775261.2|ensembl:ENSMUSG00000025758(gene)|ensembl:ENSMUST00000026858(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:Q64702|rcsb pdb:1MBY|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-8854518|refseq:NP_035625.2|dip:DIP-42244N|mint:MINT-4054168(identity) - - - figure legend:F2D|figure legend:STS1|figure legend:STS2|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/01/22 2014/10/16 rogid:DWq1aIaKl0+TykoAniMvm2EXdmY9606 rogid:L1/nN7/3X379zeA2OE3rfje+Cvc10090 intact-crc:C4E7DD2B1306392C|rigid:kBjDFTvtYEOoEo49ph/x57oC/gI false binding-associated region:287-289(MINT-4054162)|mutation disrupting interaction:295-295(MINT-4054159) mutation disrupting interaction:154-154(MINT-4054169)|binding-associated region:1-390(MINT-4054172) - - psi-mi:"MI:0083"(peptide synthesis) psi-mi:"MI:0078"(nucleotide sequence identification)