#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P25446	uniprotkb:P26040	intact:EBI-296206|uniprotkb:Q9DCQ1|uniprotkb:Q6GT31|ensembl:ENSMUSP00000025691	intact:EBI-645505|uniprotkb:Q80ZT8|uniprotkb:Q9DCI1|ensembl:ENSMUSP00000063734	psi-mi:tnr6_mouse(display_long)|uniprotkb:Fas(gene name)|psi-mi:Fas(display_short)|uniprotkb:Apt1(gene name synonym)|uniprotkb:Tnfrsf6(gene name synonym)|uniprotkb:FASLG receptor(gene name synonym)|uniprotkb:Apoptosis-mediating surface antigen FAS(gene name synonym)|uniprotkb:Apo-1 antigen(gene name synonym)	psi-mi:ezri_mouse(display_long)|uniprotkb:Vil2(gene name synonym)|uniprotkb:p81(gene name synonym)|uniprotkb:Cytovillin(gene name synonym)|uniprotkb:Villin-2(gene name synonym)|uniprotkb:Ezr(gene name)|psi-mi:Ezr(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chakrabandhu et al. (2007)	pubmed:17159908|imex:IM-10781|mint:MINT-5219434	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7159930|mint:MINT-4085294|imex:IM-10781-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|ensembl:ENSMUSG00000024778(gene)|ensembl:ENSMUST00000025691(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045121"(membrane raft)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:0036337"(Fas signaling pathway)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0005516"(calmodulin binding)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019900"(kinase binding)|go:"GO:0030141"(secretory granule)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034198"(cellular response to amino acid starvation)|refseq:NP_032013.2|go:"GO:0048536"(spleen development)|go:"GO:0050869"(negative regulation of B cell activation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070227"(lymphocyte apoptotic process)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097049"(motor neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097440"(apical dendrite)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR008063(Fas receptor)|interpro:IPR011029(DEATH-like)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR033998|interpro:IPR033999|mint:P25446|rcsb pdb:2NA6|rcsb pdb:3OQ9|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-69416|reactome:R-MMU-75157|dip:DIP-31093N|mint:MINT-4085295(identity)	refseq:NP_033536.2|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031623"(receptor internalization)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044297"(cell body)|go:"GO:0044393"(microspike)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097454"(Schwann cell microvillus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902896"(terminal web assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|interpro:IPR008954(Moesin)|mint:P26040|reactome:R-MMU-373752|reactome:R-MMU-437239|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|ensembl:ENSMUSG00000052397(gene)|ensembl:ENSMUST00000064234(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0001772"(immunological synapse)|go:"GO:0001931"(uropod)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|mint:MINT-4085296(identity)	-	-	-	figure legend:F4B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-l12)|taxid:10090(Mus musculus)	-	2007/02/07	2014/10/16	rogid:ihK7Oxh+f0U7iYAsR2TlwLX3Ep410090	rogid:PspmkV3JA32h1VGLkUgha3a59AA10090	intact-crc:FB25392AABC9D1CA|rigid:xRzdvpW7jvxDTSkQIHP6V3LjdkQ	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q61160	uniprotkb:P25446	intact:EBI-524415|uniprotkb:Q3TC37|uniprotkb:Q61082|ensembl:ENSMUSP00000033394	intact:EBI-296206|uniprotkb:Q9DCQ1|uniprotkb:Q6GT31|ensembl:ENSMUSP00000025691	psi-mi:fadd_mouse(display_long)|uniprotkb:FAS-associating death domain-containing protein(gene name synonym)|uniprotkb:Mediator of receptor induced toxicity(gene name synonym)|uniprotkb:Fadd(gene name)|psi-mi:Fadd(display_short)|uniprotkb:Mort1(gene name synonym)	psi-mi:tnr6_mouse(display_long)|uniprotkb:Fas(gene name)|psi-mi:Fas(display_short)|uniprotkb:Apt1(gene name synonym)|uniprotkb:Tnfrsf6(gene name synonym)|uniprotkb:FASLG receptor(gene name synonym)|uniprotkb:Apoptosis-mediating surface antigen FAS(gene name synonym)|uniprotkb:Apo-1 antigen(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chakrabandhu et al. (2007)	pubmed:17159908|imex:IM-10781|mint:MINT-5219434	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7159953|mint:MINT-4085334|imex:IM-10781-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000031077(gene)|ensembl:ENSMUST00000033394(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0002020"(protease binding)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0005123"(death receptor binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0030217"(T cell differentiation)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032813"(tumor necrosis factor receptor superfamily binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0035877"(death effector domain binding)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0044297"(cell body)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048535"(lymph node development)|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070236"(negative regulation of activation-induced cell death of T cells)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071550"(death-inducing signaling complex assembly)|go:"GO:0089720"(caspase binding)|go:"GO:0097049"(motor neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097342"(ripoptosome)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:2000454"(positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001875(Death effector)|interpro:IPR011029(DEATH-like)|interpro:IPR016729(FADD)|mint:Q61160|rcsb pdb:1FAD|reactome:R-MMU-140534|reactome:R-MMU-2562578|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-5357786|reactome:R-MMU-5357905|reactome:R-MMU-5675482|reactome:R-MMU-69416|reactome:R-MMU-75157|reactome:R-MMU-75158|refseq:NP_034305.1|dip:DIP-34771N|mint:MINT-4085335(identity)	go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|ensembl:ENSMUSG00000024778(gene)|ensembl:ENSMUST00000025691(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045121"(membrane raft)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:0036337"(Fas signaling pathway)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0005516"(calmodulin binding)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019900"(kinase binding)|go:"GO:0030141"(secretory granule)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034198"(cellular response to amino acid starvation)|refseq:NP_032013.2|go:"GO:0048536"(spleen development)|go:"GO:0050869"(negative regulation of B cell activation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070227"(lymphocyte apoptotic process)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097049"(motor neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097440"(apical dendrite)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR008063(Fas receptor)|interpro:IPR011029(DEATH-like)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR033998|interpro:IPR033999|mint:P25446|rcsb pdb:2NA6|rcsb pdb:3OQ9|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-69416|reactome:R-MMU-75157|dip:DIP-31093N|mint:MINT-4085338(identity)	-	-	-	figure legend:F4B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-l12)|taxid:10090(Mus musculus)	-	2007/02/07	2014/10/16	rogid:0pzBrb1MrPRQ1IL9cdXg57tneNE10090	rogid:ihK7Oxh+f0U7iYAsR2TlwLX3Ep410090	intact-crc:BB830839FB3FEE48|rigid:1HyHFIHyNSFyziEjX8hI68Ksdkk	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P25446	uniprotkb:O89110	intact:EBI-296206|uniprotkb:Q9DCQ1|uniprotkb:Q6GT31|ensembl:ENSMUSP00000025691	intact:EBI-851690|uniprotkb:O35669|ensembl:ENSMUSP00000027189|ensembl:ENSMUSP00000127375	psi-mi:tnr6_mouse(display_long)|uniprotkb:Fas(gene name)|psi-mi:Fas(display_short)|uniprotkb:Apt1(gene name synonym)|uniprotkb:Tnfrsf6(gene name synonym)|uniprotkb:FASLG receptor(gene name synonym)|uniprotkb:Apoptosis-mediating surface antigen FAS(gene name synonym)|uniprotkb:Apo-1 antigen(gene name synonym)	psi-mi:casp8_mouse(display_long)|uniprotkb:Casp8(gene name)|psi-mi:Casp8(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chakrabandhu et al. (2007)	pubmed:17159908|imex:IM-10781|mint:MINT-5219434	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7159941|mint:MINT-4085319|imex:IM-10781-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|ensembl:ENSMUSG00000024778(gene)|ensembl:ENSMUST00000025691(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045121"(membrane raft)|go:"GO:0045619"(regulation of lymphocyte differentiation)|go:"GO:0036337"(Fas signaling pathway)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0005516"(calmodulin binding)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019900"(kinase binding)|go:"GO:0030141"(secretory granule)|go:"GO:0031104"(dendrite regeneration)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034198"(cellular response to amino acid starvation)|refseq:NP_032013.2|go:"GO:0048536"(spleen development)|go:"GO:0050869"(negative regulation of B cell activation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070227"(lymphocyte apoptotic process)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097049"(motor neuron apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097440"(apical dendrite)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:1900148"(negative regulation of Schwann cell migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR008063(Fas receptor)|interpro:IPR011029(DEATH-like)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR033998|interpro:IPR033999|mint:P25446|rcsb pdb:2NA6|rcsb pdb:3OQ9|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-69416|reactome:R-MMU-75157|dip:DIP-31093N|mint:MINT-4085323(identity)	refseq:NP_001073595.1|refseq:NP_033942.1|dip:DIP-37435N|reactome:R-MMU-3371378|reactome:R-MMU-5218900|reactome:R-MMU-5357905|reactome:R-MMU-5660668|reactome:R-MMU-5675482|reactome:R-MMU-69416|reactome:R-MMU-75108|reactome:R-MMU-75153|reactome:R-MMU-75157|reactome:R-MMU-75158|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR001875(Death effector)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR011029(DEATH-like)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR016129(Peptidase C14, ICE, catalytic subunit p20, active site)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033170|mint:O89110|reactome:R-MMU-111465|reactome:R-MMU-140534|reactome:R-MMU-168638|reactome:R-MMU-2562578|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070243"(regulation of thymocyte apoptotic process)|go:"GO:0070269"(pyroptosis)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097153"(cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0097199"(cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:0097264"(self proteolysis)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097342"(ripoptosome)|ensembl:ENSMUST00000027189(transcript)|ensembl:ENSMUST00000165549(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001841"(neural tube formation)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007507"(heart development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016485"(protein processing)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|ensembl:ENSMUSG00000026029(gene)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035877"(death effector domain binding)|go:"GO:0036462"(TRAIL-activated apoptotic signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0048738"(cardiac muscle tissue development)|reactome:R-MMU-264870|mint:MINT-4085320(identity)	-	-	-	figure legend:F4B|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-l12)|taxid:10090(Mus musculus)	-	2007/02/07	2014/10/16	rogid:ihK7Oxh+f0U7iYAsR2TlwLX3Ep410090	rogid:cugP6s7CldE0MbwvCxTcams7feA10090	intact-crc:F9D5A265F0420AC2|rigid:brNeqDlEl1zotwn0nBYmw3bhO0I	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P06241	uniprotkb:P25445	intact:EBI-515315|uniprotkb:Q16248|uniprotkb:Q5R3A6|uniprotkb:Q5R3A7|uniprotkb:Q8N5D7|uniprotkb:B5BU57|intact:EBI-2561531|uniprotkb:E1P557|uniprotkb:H0UI48|ensembl:ENSP00000346671|ensembl:ENSP00000357656	intact:EBI-494743|uniprotkb:Q14292|uniprotkb:Q14293|uniprotkb:Q14294|uniprotkb:Q14295|uniprotkb:Q16652|uniprotkb:Q6SSE9|uniprotkb:Q5T9P1|uniprotkb:Q5T9P2|uniprotkb:A9UJX4|uniprotkb:B6VNV4|uniprotkb:Q5T9P3|ensembl:ENSP00000498466	psi-mi:fyn_human(display_long)|uniprotkb:p59-Fyn(gene name synonym)|uniprotkb:Proto-oncogene c-Fyn(gene name synonym)|uniprotkb:Src-like kinase(gene name synonym)|uniprotkb:FYN(gene name)|psi-mi:FYN(display_short)|uniprotkb:Proto-oncogene Syn(gene name synonym)	psi-mi:tnr6_human(display_long)|uniprotkb:FASLG receptor(gene name synonym)|uniprotkb:Apoptosis-mediating surface antigen FAS(gene name synonym)|uniprotkb:Apo-1 antigen(gene name synonym)|uniprotkb:FAS(gene name)|psi-mi:FAS(display_short)|uniprotkb:APT1(gene name synonym)|uniprotkb:TNFRSF6(gene name synonym)|uniprotkb:FAS1(gene name synonym)	psi-mi:"MI:0029"(cosedimentation through density gradient)	Chakrabandhu et al. (2007)	pubmed:17159908|imex:IM-10781|mint:MINT-5219434	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-7160127|mint:MINT-4085360|imex:IM-10781-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_005266947.1|refseq:XP_005266949.1|refseq:NP_002028.1|refseq:NP_694592.1|refseq:NP_694593.1|refseq:XP_016866139.1|refseq:XP_016866140.1|refseq:XP_016866141.1|refseq:XP_016866142.1|refseq:XP_016866143.1|dip:DIP-33876N|ensembl:ENSG00000010810(gene)|ensembl:ENST00000354650(transcript)|ensembl:ENST00000368667(transcript)|go:"GO:0000304"(response to singlet oxygen)|go:"GO:0001764"(neuron migration)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0003015"(heart process)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007612"(learning)|go:"GO:0007631"(feeding behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042610"(CD8 receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0044297"(cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050798"(activated T cell proliferation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097386"(glial cell projection)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900449"(regulation of glutamate receptor signaling pathway)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905430"(cellular response to glycine)|go:"GO:1905477"(positive regulation of protein localization to membrane)|go:"GO:1905664"(regulation of calcium ion import across plasma membrane)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR035750|interpro:IPR036028|interpro:IPR036860|mint:P06241|rcsb pdb:1A0N|rcsb pdb:1AOT|rcsb pdb:1AOU|rcsb pdb:1AVZ|rcsb pdb:1AZG|rcsb pdb:1EFN|rcsb pdb:1FYN|rcsb pdb:1G83|rcsb pdb:1M27|rcsb pdb:1NYF|rcsb pdb:1NYG|rcsb pdb:1SHF|rcsb pdb:1ZBJ|rcsb pdb:2DQ7|rcsb pdb:2MQI|rcsb pdb:2MRJ|rcsb pdb:2MRK|rcsb pdb:3H0F|rcsb pdb:3H0H|rcsb pdb:3H0I|rcsb pdb:3UA6|rcsb pdb:3UA7|rcsb pdb:4D8D|rcsb pdb:4EIK|rcsb pdb:4U17|rcsb pdb:4U1P|rcsb pdb:4ZNX|rcsb pdb:5ZAU|rcsb pdb:6EDF|rcsb pdb:6IPY|rcsb pdb:6IPZ|reactome:R-HSA-114604|reactome:R-HSA-1227986|reactome:R-HSA-1257604|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-164944|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2424491|reactome:R-HSA-2682334|reactome:R-HSA-2730905|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-389357|reactome:R-HSA-389359|reactome:R-HSA-389513|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-399954|reactome:R-HSA-399955|reactome:R-HSA-399956|reactome:R-HSA-418885|reactome:R-HSA-4420097|reactome:R-HSA-5621480|reactome:R-HSA-5621575|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-75892|reactome:R-HSA-8866376|reactome:R-HSA-9032500|reactome:R-HSA-9032759|reactome:R-HSA-912631|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-9706374|reactome:R-HSA-983695|reactome:R-HSA-9670439|mint:MINT-4085361(identity)	refseq:NP_000034.1|refseq:NP_690610.1|refseq:NP_690611.1|refseq:NP_001307548.1|dip:DIP-924N|ensembl:ENSG00000026103(gene)|ensembl:ENST00000652046(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005031"(tumor necrosis factor-activated receptor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019900"(kinase binding)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031265"(CD95 death-inducing signaling complex)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0036337"(Fas signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0097049"(motor neuron apoptotic process)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001368(TNFR/CD27/30/40/95 cysteine-rich region)|interpro:IPR008063(Fas receptor)|interpro:IPR011029(DEATH-like)|interpro:IPR033998|interpro:IPR033999|mint:P25445|rcsb pdb:1BZI|rcsb pdb:1DDF|rcsb pdb:2NA7|rcsb pdb:3EWT|rcsb pdb:3THM|rcsb pdb:3TJE|reactome:R-HSA-140534|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-6803211|reactome:R-HSA-69416|reactome:R-HSA-75157|rcsb pdb:3EZQ|mint:MINT-4085364(identity)	go:"GO:0045121"(membrane raft)	-	-	figure legend:F3C|comment:homomint|comment:mint|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/02/07	2014/10/16	rogid:GM5wIXENkJgPKwHN+UZBIqUfH6U9606	rogid:Yz5oIuvCmfV62Fpd/XjXGmSDZms9606	intact-crc:1DCA95CE913D10C7|rigid:Z/LtzdP+nds8A3eCxloYlq6c7zw	false	-	green fluorescent protein tag:?-?(MINT-4085380)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)