#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9HB75	uniprotkb:Q9HB75	intact:EBI-520427|ensembl:ENSP00000337797|uniprotkb:Q59FD1|uniprotkb:Q59H10|uniprotkb:Q59HC7|uniprotkb:Q7Z4P8|uniprotkb:Q8NC89|uniprotkb:Q8NDL2|uniprotkb:Q96C25|uniprotkb:Q9NRE6	intact:EBI-520427|ensembl:ENSP00000337797|uniprotkb:Q59FD1|uniprotkb:Q59H10|uniprotkb:Q59HC7|uniprotkb:Q7Z4P8|uniprotkb:Q8NC89|uniprotkb:Q8NDL2|uniprotkb:Q96C25|uniprotkb:Q9NRE6	psi-mi:pidd1_human(display_long)|uniprotkb:PIDD1(gene name)|psi-mi:PIDD1(display_short)|uniprotkb:LRDD(gene name synonym)|uniprotkb:Leucine-rich repeat and death domain-containing protein(gene name synonym)|uniprotkb:PIDD(gene name synonym)	psi-mi:pidd1_human(display_long)|uniprotkb:PIDD1(gene name)|psi-mi:PIDD1(display_short)|uniprotkb:LRDD(gene name synonym)|uniprotkb:Leucine-rich repeat and death domain-containing protein(gene name synonym)|uniprotkb:PIDD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tinel et al. (2007)	pubmed:17159900|imex:IM-11380|mint:MINT-5219422	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7155221|mint:MINT-4054896|imex:IM-11380-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_665893.2|refseq:NP_665894.2|ensembl:ENSG00000177595(gene)|ensembl:ENST00000347755(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:XP_011518512.1|refseq:XP_011518513.1|refseq:XP_016873482.1|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR011029(DEATH-like)|interpro:IPR019502|interpro:IPR032675|mint:Q9HB75|rcsb pdb:2OF5|reactome:R-HSA-6803207|mint:MINT-4054898(identity)	refseq:NP_665893.2|refseq:NP_665894.2|ensembl:ENSG00000177595(gene)|ensembl:ENST00000347755(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:XP_011518512.1|refseq:XP_011518513.1|refseq:XP_016873482.1|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR011029(DEATH-like)|interpro:IPR019502|interpro:IPR032675|mint:Q9HB75|rcsb pdb:2OF5|reactome:R-HSA-6803207|mint:MINT-4054897(identity)	-	-	-	figure legend:F1D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/01/22	2014/10/16	rogid:n0LSBUZQ057RjeGw0h+yCoXgi0w9606	rogid:n0LSBUZQ057RjeGw0h+yCoXgi0w9606	intact-crc:80108B6FE3AE29B6|rigid:QTn+cdQ/1IbrY/vJvyKAqwU9JmM	false	tag:?-?(MINT-4054914)|binding-associated region:147-602(MINT-4054918)	binding-associated region:558-910(MINT-4054929)|flag tag:?-?(MINT-4054925)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HB75	uniprotkb:P78560	intact:EBI-520427|ensembl:ENSP00000337797|uniprotkb:Q59FD1|uniprotkb:Q59H10|uniprotkb:Q59HC7|uniprotkb:Q7Z4P8|uniprotkb:Q8NC89|uniprotkb:Q8NDL2|uniprotkb:Q96C25|uniprotkb:Q9NRE6	intact:EBI-520375|uniprotkb:B7Z2Q5|ensembl:ENSP00000327647|ensembl:ENSP00000439068	psi-mi:pidd1_human(display_long)|uniprotkb:PIDD1(gene name)|psi-mi:PIDD1(display_short)|uniprotkb:LRDD(gene name synonym)|uniprotkb:Leucine-rich repeat and death domain-containing protein(gene name synonym)|uniprotkb:PIDD(gene name synonym)	psi-mi:cradd_human(display_long)|uniprotkb:Caspase and RIP adapter with death domain(gene name synonym)|uniprotkb:RIP-associated protein with a death domain(gene name synonym)|uniprotkb:CRADD(gene name)|psi-mi:CRADD(display_short)|uniprotkb:RAIDD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tinel et al. (2007)	pubmed:17159900|imex:IM-11380|mint:MINT-5219422	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7155403|mint:MINT-4054932|imex:IM-11380-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_665893.2|refseq:NP_665894.2|ensembl:ENSG00000177595(gene)|ensembl:ENST00000347755(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:XP_011518512.1|refseq:XP_011518513.1|refseq:XP_016873482.1|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR011029(DEATH-like)|interpro:IPR019502|interpro:IPR032675|mint:Q9HB75|rcsb pdb:2OF5|reactome:R-HSA-6803207|mint:MINT-4054940(identity)	refseq:NP_003796.1|refseq:NP_001307029.1|refseq:NP_001307030.1|refseq:NP_001307028.1|refseq:XP_016875633.1|ensembl:ENSG00000169372(gene)|ensembl:ENST00000332896(transcript)|ensembl:ENST00000542893(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0070513"(death domain binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR037926|interpro:IPR037939|interpro:IPR042148|mint:P78560|rcsb pdb:2O71|rcsb pdb:2OF5|rcsb pdb:3CRD|reactome:R-HSA-6803207|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|mint:MINT-4054933(identity)	-	-	-	figure legend:F3A|figure legend:F4B|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/01/22	2014/10/16	rogid:n0LSBUZQ057RjeGw0h+yCoXgi0w9606	rogid:koYvv+L+23G4lMEFIFmYYBNaNkk9606	intact-crc:72BA4F6AC8071A0F|rigid:zbnLpmFlPQmERiXAv0wQzHch1b8	false	mutation decreasing interaction:745-745(MINT-4054968)|mutation disrupting interaction:745-745,603-603(MINT-4054971)|flag tag:?-?(MINT-4054945)|binding-associated region:446-910(MINT-4054941)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0086"(polyclonal antibody western blot)
uniprotkb:Q9HB75	uniprotkb:Q13546	intact:EBI-520427|ensembl:ENSP00000337797|uniprotkb:Q59FD1|uniprotkb:Q59H10|uniprotkb:Q59HC7|uniprotkb:Q7Z4P8|uniprotkb:Q8NC89|uniprotkb:Q8NDL2|uniprotkb:Q96C25|uniprotkb:Q9NRE6	intact:EBI-358507|uniprotkb:A0AV89|uniprotkb:B2RAG1|uniprotkb:B4E3F9|uniprotkb:Q59H33|uniprotkb:Q13180|ensembl:ENSP00000259808	psi-mi:pidd1_human(display_long)|uniprotkb:PIDD1(gene name)|psi-mi:PIDD1(display_short)|uniprotkb:LRDD(gene name synonym)|uniprotkb:Leucine-rich repeat and death domain-containing protein(gene name synonym)|uniprotkb:PIDD(gene name synonym)	psi-mi:ripk1_human(display_long)|uniprotkb:RIPK1(gene name)|psi-mi:RIPK1(display_short)|uniprotkb:RIP(gene name synonym)|uniprotkb:Cell death protein RIP(gene name synonym)|uniprotkb:RIP1(gene name synonym)|uniprotkb:Receptor-interacting protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tinel et al. (2007)	pubmed:17159900|imex:IM-11380|mint:MINT-5219422	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7155477|mint:MINT-4055007|imex:IM-11380-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_665893.2|refseq:NP_665894.2|ensembl:ENSG00000177595(gene)|ensembl:ENST00000347755(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:XP_011518512.1|refseq:XP_011518513.1|refseq:XP_016873482.1|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR011029(DEATH-like)|interpro:IPR019502|interpro:IPR032675|mint:Q9HB75|rcsb pdb:2OF5|reactome:R-HSA-6803207|mint:MINT-4055008(identity)	refseq:NP_003795.2|refseq:XP_005249514.2|dip:DIP-433N|ensembl:ENSG00000137275(gene)|ensembl:ENST00000259808(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004706"(JUN kinase kinase kinase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008219"(cell death)|go:"GO:0010008"(endosome membrane)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0031264"(death-inducing signaling complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043235"(receptor complex)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060545"(positive regulation of necroptotic process)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070105"(positive regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070231"(T cell apoptotic process)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070513"(death domain binding)|go:"GO:0070926"("regulation of ATP:ADP antiporter activity")|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097300"(programmed necrotic cell death)|go:"GO:0097342"(ripoptosome)|go:"GO:0097343"(ripoptosome assembly)|go:"GO:0097527"(necroptotic signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905206"(positive regulation of hydrogen peroxide-induced cell death)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR025735|interpro:IPR037934|mint:Q13546|rcsb pdb:4ITH|rcsb pdb:4ITI|rcsb pdb:4ITJ|rcsb pdb:4NEU|rcsb pdb:5HX6|rcsb pdb:5TX5|rcsb pdb:5V7Z|rcsb pdb:6AC5|rcsb pdb:6C3E|rcsb pdb:6C4D|rcsb pdb:6HHO|rcsb pdb:6NW2|rcsb pdb:6NYH|rcsb pdb:6OCQ|rcsb pdb:6R5F|rcsb pdb:6RLN|reactome:R-HSA-140534|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-2562578|reactome:R-HSA-3295583|reactome:R-HSA-3371378|reactome:R-HSA-5213460|reactome:R-HSA-5218900|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-69416|reactome:R-HSA-75893|reactome:R-HSA-9013957|reactome:R-HSA-933543|reactome:R-HSA-937041|reactome:R-HSA-9679191|reactome:R-HSA-9686347|reactome:R-HSA-9693928|go:"GO:0070266"(necroptotic process)|mint:MINT-4055015(identity)	-	-	-	figure legend:F5D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/01/22	2014/10/16	rogid:n0LSBUZQ057RjeGw0h+yCoXgi0w9606	rogid:P1pQanTLVGi2Oic1QNeELpcdL2M9606	intact-crc:A91D729E6E110A0E|rigid:qZ2uJ5UOXqOUKhw/Ux8jxyVzOn4	false	binding-associated region:446-910(MINT-4055009)|tag:?-?(MINT-4055013)	tag:?-?(MINT-4055055)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9HB75	uniprotkb:P78560	intact:EBI-520427|ensembl:ENSP00000337797|uniprotkb:Q59FD1|uniprotkb:Q59H10|uniprotkb:Q59HC7|uniprotkb:Q7Z4P8|uniprotkb:Q8NC89|uniprotkb:Q8NDL2|uniprotkb:Q96C25|uniprotkb:Q9NRE6	intact:EBI-520375|uniprotkb:B7Z2Q5|ensembl:ENSP00000327647|ensembl:ENSP00000439068	psi-mi:pidd1_human(display_long)|uniprotkb:PIDD1(gene name)|psi-mi:PIDD1(display_short)|uniprotkb:LRDD(gene name synonym)|uniprotkb:Leucine-rich repeat and death domain-containing protein(gene name synonym)|uniprotkb:PIDD(gene name synonym)	psi-mi:cradd_human(display_long)|uniprotkb:Caspase and RIP adapter with death domain(gene name synonym)|uniprotkb:RIP-associated protein with a death domain(gene name synonym)|uniprotkb:CRADD(gene name)|psi-mi:CRADD(display_short)|uniprotkb:RAIDD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Tinel et al. (2007)	pubmed:17159900|imex:IM-11380|mint:MINT-5219422	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7155434|mint:MINT-4054980|imex:IM-11380-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_665893.2|refseq:NP_665894.2|ensembl:ENSG00000177595(gene)|ensembl:ENST00000347755(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|refseq:XP_011518512.1|refseq:XP_011518513.1|refseq:XP_016873482.1|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR011029(DEATH-like)|interpro:IPR019502|interpro:IPR032675|mint:Q9HB75|rcsb pdb:2OF5|reactome:R-HSA-6803207|mint:MINT-4054984(identity)	refseq:NP_003796.1|refseq:NP_001307029.1|refseq:NP_001307030.1|refseq:NP_001307028.1|refseq:XP_016875633.1|ensembl:ENSG00000169372(gene)|ensembl:ENST00000332896(transcript)|ensembl:ENST00000542893(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0070513"(death domain binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000488(Death)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR011029(DEATH-like)|interpro:IPR037926|interpro:IPR037939|interpro:IPR042148|mint:P78560|rcsb pdb:2O71|rcsb pdb:2OF5|rcsb pdb:3CRD|reactome:R-HSA-6803207|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|mint:MINT-4054981(identity)	-	-	-	figure legend:F4D|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2007/01/22	2014/10/16	rogid:n0LSBUZQ057RjeGw0h+yCoXgi0w9606	rogid:koYvv+L+23G4lMEFIFmYYBNaNkk9606	intact-crc:3EB23478A27FA7FC|rigid:zbnLpmFlPQmERiXAv0wQzHch1b8	false	binding-associated region:558-910(MINT-4054996)|flag tag:?-?(MINT-4054992)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)