#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P91666	uniprotkb:O77430	intact:EBI-7085629|intact:MINT-4055177	intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474	psi-mi:p91666_drome(display_long)|uniprotkb:Rca1(gene name)|psi-mi:Rca1(display_short)|uniprotkb:rca1(gene name synonym)|uniprotkb:CG10800(orf name)	psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Zielke et al. (2006)	pubmed:17099689|imex:IM-11494|mint:MINT-5219320	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7085623|mint:MINT-4055189|imex:IM-11494-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|mint:P91666|flybase:FBgn0017551|mint:MINT-4055191(identity)	refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168|mint:MINT-4055190(identity)	-	comment:mint	-	figure legend:F2A|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2007/01/22	2014/10/16	rogid:HDHjhoZxr1PTroQec3SlF3ok6io7227	rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227	intact-crc:0FDBBAB6DA8EA0CA|rigid:pWd3+UXDHszsC1ChLINOvtCkURQ	false	binding-associated region:164-223(MINT-4055206)|flag tag:?-?(MINT-4055201)	ha tag:?-?(MINT-4055195)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q24311	uniprotkb:O77430	intact:EBI-136038|uniprotkb:A4UZ78|ensemblmetazoa:FBpp0087921|ensemblmetazoa:FBpp0087922|ensemblmetazoa:FBpp0087923|ensemblmetazoa:FBpp0087924|uniprotkb:Q0E9G0|uniprotkb:Q9V312	intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474	psi-mi:cul1_drome(display_long)|uniprotkb:Cul1(gene name)|psi-mi:Cul1(display_short)|uniprotkb:Lin-19 homolog protein(gene name synonym)|uniprotkb:cul-1(gene name synonym)|uniprotkb:lin19(gene name synonym)|uniprotkb:CG1877(orf name)	psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Zielke et al. (2006)	pubmed:17099689|imex:IM-11494|mint:MINT-5219320	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7085698|mint:MINT-4055260|imex:IM-11494-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_523655.1|refseq:NP_724621.1|refseq:NP_724622.1|refseq:NP_724623.1|flybase:FBgn0015509|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904801"(positive regulation of neuron remodeling)|ensemblmetazoa:FBgn0015509(gene)|ensemblmetazoa:FBtr0088845(transcript)|ensemblmetazoa:FBtr0088846(transcript)|ensemblmetazoa:FBtr0088847(transcript)|ensemblmetazoa:FBtr0088848(transcript)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q24311|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168|dip:DIP-19461N|mint:MINT-4055261(identity)	refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168|mint:MINT-4055265(identity)	-	-	-	figure legend:F2C|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2007/01/22	2014/10/16	rogid:uik6AV9MpfMBKBZoYZSxvCl5bTc7227	rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227	intact-crc:8F75D8BE4DBEA364|rigid:J1oPCXolY80EWCMtFo55Kg5Nc+Y	false	-	ha tag:?-?(MINT-4055268)	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P91666	uniprotkb:O77430	intact:EBI-7085629|intact:MINT-4055177	intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474	psi-mi:p91666_drome(display_long)|uniprotkb:Rca1(gene name)|psi-mi:Rca1(display_short)|uniprotkb:rca1(gene name synonym)|uniprotkb:CG10800(orf name)	psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Zielke et al. (2006)	pubmed:17099689|imex:IM-11494|mint:MINT-5219320	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7085660|mint:MINT-4055210|imex:IM-11494-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|mint:P91666|flybase:FBgn0017551|mint:MINT-4055211(identity)	refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168|mint:MINT-4055220(identity)	-	comment:mint	-	figure legend:F2B|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2007/01/22	2014/10/16	rogid:HDHjhoZxr1PTroQec3SlF3ok6io7227	rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227	intact-crc:32F5F3B18DBB6C02|rigid:pWd3+UXDHszsC1ChLINOvtCkURQ	false	flag tag:?-?(MINT-4055217)|binding-associated region:164-223(MINT-4055212)	ha tag:?-?(MINT-4055223)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P91666	uniprotkb:Q24311	intact:EBI-7085629|intact:MINT-4055177	intact:EBI-136038|uniprotkb:A4UZ78|ensemblmetazoa:FBpp0087921|ensemblmetazoa:FBpp0087922|ensemblmetazoa:FBpp0087923|ensemblmetazoa:FBpp0087924|uniprotkb:Q0E9G0|uniprotkb:Q9V312	psi-mi:p91666_drome(display_long)|uniprotkb:Rca1(gene name)|psi-mi:Rca1(display_short)|uniprotkb:rca1(gene name synonym)|uniprotkb:CG10800(orf name)	psi-mi:cul1_drome(display_long)|uniprotkb:Cul1(gene name)|psi-mi:Cul1(display_short)|uniprotkb:Lin-19 homolog protein(gene name synonym)|uniprotkb:cul-1(gene name synonym)|uniprotkb:lin19(gene name synonym)|uniprotkb:CG1877(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Zielke et al. (2006)	pubmed:17099689|imex:IM-11494|mint:MINT-5219320	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7085683|mint:MINT-4055232|imex:IM-11494-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|mint:P91666|flybase:FBgn0017551|mint:MINT-4055233(identity)	refseq:NP_523655.1|refseq:NP_724621.1|refseq:NP_724622.1|refseq:NP_724623.1|flybase:FBgn0015509|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904801"(positive regulation of neuron remodeling)|ensemblmetazoa:FBgn0015509(gene)|ensemblmetazoa:FBtr0088845(transcript)|ensemblmetazoa:FBtr0088846(transcript)|ensemblmetazoa:FBtr0088847(transcript)|ensemblmetazoa:FBtr0088848(transcript)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q24311|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168|dip:DIP-19461N|mint:MINT-4055242(identity)	-	comment:mint	-	figure legend:F2C|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2007/01/22	2014/10/16	rogid:HDHjhoZxr1PTroQec3SlF3ok6io7227	rogid:uik6AV9MpfMBKBZoYZSxvCl5bTc7227	intact-crc:3B235D20D6036928|rigid:/IkEhqfQjporYnRUiDJ7IBjTeOA	false	flag tag:?-?(MINT-4055234)	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0113"(western blot)
uniprotkb:P91666	uniprotkb:Q24311	intact:EBI-7085629|intact:MINT-4055177	intact:EBI-136038|uniprotkb:A4UZ78|ensemblmetazoa:FBpp0087921|ensemblmetazoa:FBpp0087922|ensemblmetazoa:FBpp0087923|ensemblmetazoa:FBpp0087924|uniprotkb:Q0E9G0|uniprotkb:Q9V312	psi-mi:p91666_drome(display_long)|uniprotkb:Rca1(gene name)|psi-mi:Rca1(display_short)|uniprotkb:rca1(gene name synonym)|uniprotkb:CG10800(orf name)	psi-mi:cul1_drome(display_long)|uniprotkb:Cul1(gene name)|psi-mi:Cul1(display_short)|uniprotkb:Lin-19 homolog protein(gene name synonym)|uniprotkb:cul-1(gene name synonym)|uniprotkb:lin19(gene name synonym)|uniprotkb:CG1877(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Zielke et al. (2006)	pubmed:17099689|imex:IM-11494|mint:MINT-5219320	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7085748|mint:MINT-4055296|imex:IM-11494-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|mint:P91666|flybase:FBgn0017551|mint:MINT-4055303(identity)	refseq:NP_523655.1|refseq:NP_724621.1|refseq:NP_724622.1|refseq:NP_724623.1|flybase:FBgn0015509|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904801"(positive regulation of neuron remodeling)|ensemblmetazoa:FBgn0015509(gene)|ensemblmetazoa:FBtr0088845(transcript)|ensemblmetazoa:FBtr0088846(transcript)|ensemblmetazoa:FBtr0088847(transcript)|ensemblmetazoa:FBtr0088848(transcript)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q24311|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168|dip:DIP-19461N|mint:MINT-4055297(identity)	-	comment:mint	-	figure legend:F2D|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2007/01/22	2014/10/16	rogid:HDHjhoZxr1PTroQec3SlF3ok6io7227	rogid:uik6AV9MpfMBKBZoYZSxvCl5bTc7227	intact-crc:0470A30700192746|rigid:/IkEhqfQjporYnRUiDJ7IBjTeOA	false	flag tag:?-?(MINT-4055306)	myc tag:?-?(MINT-4055299)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q24311	uniprotkb:O77430	intact:EBI-136038|uniprotkb:A4UZ78|ensemblmetazoa:FBpp0087921|ensemblmetazoa:FBpp0087922|ensemblmetazoa:FBpp0087923|ensemblmetazoa:FBpp0087924|uniprotkb:Q0E9G0|uniprotkb:Q9V312	intact:EBI-180180|intact:EBI-1628435|ensemblmetazoa:FBpp0070118|ensemblmetazoa:FBpp0070119|ensemblmetazoa:FBpp0070120|ensemblmetazoa:FBpp0070121|ensemblmetazoa:FBpp0070122|ensemblmetazoa:FBpp0070123|ensemblmetazoa:FBpp0070124|ensemblmetazoa:FBpp0099971|ensemblmetazoa:FBpp0311474	psi-mi:cul1_drome(display_long)|uniprotkb:Cul1(gene name)|psi-mi:Cul1(display_short)|uniprotkb:Lin-19 homolog protein(gene name synonym)|uniprotkb:cul-1(gene name synonym)|uniprotkb:lin19(gene name synonym)|uniprotkb:CG1877(orf name)	psi-mi:o77430_drome(display_long)|uniprotkb:SkpA(gene name)|psi-mi:SkpA(display_short)|uniprotkb:Dredd(gene name synonym)|uniprotkb:"EG:115C2.4"(gene name synonym)|uniprotkb:skpA(gene name synonym)|uniprotkb:skpA-RC(gene name synonym)|uniprotkb:skpA-RH(gene name synonym)|uniprotkb:Dmel\CG16983(gene name synonym)|uniprotkb:SKP1(gene name synonym)|uniprotkb:SKPA(gene name synonym)|uniprotkb:Skp(gene name synonym)|uniprotkb:Skp1(gene name synonym)|uniprotkb:anon-WO03040301.234(gene name synonym)|uniprotkb:anon-WO03040301.236(gene name synonym)|uniprotkb:anon-WO03040301.238(gene name synonym)|uniprotkb:dSKP1(gene name synonym)|uniprotkb:dSkp-1(gene name synonym)|uniprotkb:dSkpA(gene name synonym)|uniprotkb:dskpA(gene name synonym)|uniprotkb:"l(1)G0037"(gene name synonym)|uniprotkb:"l(1)G0058"(gene name synonym)|uniprotkb:"l(1)G0109"(gene name synonym)|uniprotkb:"l(1)G0389"(gene name synonym)|uniprotkb:spkA(gene name synonym)|uniprotkb:Dmel_CG16983(orf name)|uniprotkb:CG16983(orf name)|uniprotkb:dSkip-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Zielke et al. (2006)	pubmed:17099689|imex:IM-11494|mint:MINT-5219320	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	taxid:7227(drome)|taxid:7227("Drosophila melanogaster (Fruit fly)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-7085729|mint:MINT-4055277|imex:IM-11494-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_523655.1|refseq:NP_724621.1|refseq:NP_724622.1|refseq:NP_724623.1|flybase:FBgn0015509|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1904801"(positive regulation of neuron remodeling)|ensemblmetazoa:FBgn0015509(gene)|ensemblmetazoa:FBtr0088845(transcript)|ensemblmetazoa:FBtr0088846(transcript)|ensemblmetazoa:FBtr0088847(transcript)|ensemblmetazoa:FBtr0088848(transcript)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q24311|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168|dip:DIP-19461N|mint:MINT-4055284(identity)	refseq:NP_001033818.1|refseq:NP_477390.1|refseq:NP_726690.1|refseq:NP_726691.1|refseq:NP_726692.1|refseq:NP_726693.1|refseq:NP_726694.1|refseq:NP_726695.1|flybase:FBgn0025637|refseq:NP_001284755.1|dip:DIP-18869N|ensemblmetazoa:FBgn0025637(gene)|ensemblmetazoa:FBtr0070123(transcript)|ensemblmetazoa:FBtr0070124(transcript)|ensemblmetazoa:FBtr0070125(transcript)|ensemblmetazoa:FBtr0070126(transcript)|ensemblmetazoa:FBtr0070127(transcript)|ensemblmetazoa:FBtr0070128(transcript)|ensemblmetazoa:FBtr0070129(transcript)|ensemblmetazoa:FBtr0100530(transcript)|ensemblmetazoa:FBtr0345314(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002785"(negative regulation of antimicrobial peptide production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016322"(neuron remodeling)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0042023"(DNA endoreduplication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045886"(negative regulation of synaptic assembly at neuromuscular junction)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051298"(centrosome duplication)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061060"(negative regulation of peptidoglycan recognition protein signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1905088"(positive regulation of synaptonemal complex assembly)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:O77430|reactome:R-DME-187577|reactome:R-DME-195253|reactome:R-DME-209360|reactome:R-DME-209461|reactome:R-DME-5610780|reactome:R-DME-5610785|reactome:R-DME-68949|reactome:R-DME-69231|reactome:R-DME-8854050|reactome:R-DME-8939902|reactome:R-DME-8951664|reactome:R-DME-9020702|reactome:R-DME-917937|reactome:R-DME-983168|mint:MINT-4055278(identity)	-	-	-	figure legend:F2E|comment:homomint|comment:mint|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7227(drome-schneider_2)|taxid:7227(Drosophila melanogaster late embryo cells)	-	2007/01/22	2014/10/16	rogid:uik6AV9MpfMBKBZoYZSxvCl5bTc7227	rogid:o/doJAXzyTf6sKVVNWBxjFy5De07227	intact-crc:13608496BDB50450|rigid:J1oPCXolY80EWCMtFo55Kg5Nc+Y	false	myc tag:?-?(MINT-4055293)	ha tag:?-?(MINT-4055279)	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)