#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O74991 uniprotkb:Q9Y709 intact:EBI-1153554|ensemblfungi:"SPCC338.16.1:pep" intact:EBI-1172248|ensemblfungi:"SPBC409.05.1:pep" psi-mi:pof3_schpo(display_long)|uniprotkb:pof3(gene name)|psi-mi:pof3(display_short)|uniprotkb:SPCC338.16(orf name) psi-mi:skp1_schpo(display_long)|uniprotkb:skp1(gene name)|psi-mi:skp1(display_short)|uniprotkb:psh1(gene name synonym)|uniprotkb:sph1(gene name synonym)|uniprotkb:SPBC409.05(orf name)|uniprotkb:P19/Skp1 homolog(gene name synonym) psi-mi:"MI:0018"(two hybrid) Mamnun et al. (2006) pubmed:16997270|imex:IM-19919 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1203661|imex:IM-19919-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019734|interpro:IPR036047|ensemblfungi:SPCC338.16(gene)|ensemblfungi:SPCC338.16.1(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0061806"(regulation of DNA recombination at centromere)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|interpro:IPR032675|refseq:NP_588152.1|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR011990(Tetratricopeptide-like helical) ensemblfungi:SPBC409.05(gene)|ensemblfungi:SPBC409.05.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0017117"(single-stranded DNA-dependent ATP-dependent DNA helicase complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0043291"(RAVE complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0060542"(regulation of strand invasion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070647"(protein modification by small protein conjugation or removal)|go:"GO:0097602"(cullin family protein binding)|go:"GO:0101026"(mitotic nuclear membrane biogenesis)|reactome:R-SPO-174113|reactome:R-SPO-68949|reactome:R-SPO-8854050|reactome:R-SPO-8951664|reactome:R-SPO-983168|refseq:NP_595455.1|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR001232(SKP1 component)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|mint:Q9Y709|interpro:IPR036296 - - - figure legend:Figure 1A.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/02/19 2014/10/16 rogid:pGT/etfX8G8yABFJufbEKwKAmHk284812 rogid:XoPbtkSSDN7NGIHiiHBf0tx5nBY284812 intact-crc:D006C72D5029E5FB|rigid:gRxgbM85RKyLayLDaz3yMNuEsSE false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O74991 uniprotkb:Q9C107 intact:EBI-1153554|ensemblfungi:"SPCC338.16.1:pep" intact:EBI-1203666|ensemblfungi:"SPAPB1E7.02c.1:pep" psi-mi:pof3_schpo(display_long)|uniprotkb:pof3(gene name)|psi-mi:pof3(display_short)|uniprotkb:SPCC338.16(orf name) psi-mi:mcl1_schpo(display_long)|uniprotkb:mcl1(gene name)|psi-mi:mcl1(display_short)|uniprotkb:SPAPB1E7.02c(orf name)|uniprotkb:slr3(gene name synonym)|uniprotkb:DNA polymerase alpha accessory factor Mcl1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Mamnun et al. (2006) pubmed:16997270|imex:IM-19919 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1203683|imex:IM-19919-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019734|interpro:IPR036047|ensemblfungi:SPCC338.16(gene)|ensemblfungi:SPCC338.16.1(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0061806"(regulation of DNA recombination at centromere)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|interpro:IPR032675|refseq:NP_588152.1|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR011990(Tetratricopeptide-like helical) refseq:NP_594128.1|interpro:IPR022100|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR024977|mint:Q9C107|ensemblfungi:SPAPB1E7.02c(gene)|ensemblfungi:SPAPB1E7.02c.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0061641"(CENP-A containing chromatin organization)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|interpro:IPR036322 - - - figure legend:Figure 1A.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/02/19 2014/10/16 rogid:pGT/etfX8G8yABFJufbEKwKAmHk284812 rogid:D3mV0rIaeqOhafHjCccHWnTNQgk284812 intact-crc:621B809AC1B6204B|rigid:Q+jYEAm+3oMddyNWq8+mQDBTWSQ false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O74991 uniprotkb:Q9Y709 intact:EBI-1153554|ensemblfungi:"SPCC338.16.1:pep" intact:EBI-1172248|ensemblfungi:"SPBC409.05.1:pep" psi-mi:pof3_schpo(display_long)|uniprotkb:pof3(gene name)|psi-mi:pof3(display_short)|uniprotkb:SPCC338.16(orf name) psi-mi:skp1_schpo(display_long)|uniprotkb:skp1(gene name)|psi-mi:skp1(display_short)|uniprotkb:psh1(gene name synonym)|uniprotkb:sph1(gene name synonym)|uniprotkb:SPBC409.05(orf name)|uniprotkb:P19/Skp1 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mamnun et al. (2006) pubmed:16997270|imex:IM-19919 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1203697|imex:IM-19919-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019734|interpro:IPR036047|ensemblfungi:SPCC338.16(gene)|ensemblfungi:SPCC338.16.1(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0061806"(regulation of DNA recombination at centromere)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|interpro:IPR032675|refseq:NP_588152.1|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR011990(Tetratricopeptide-like helical) ensemblfungi:SPBC409.05(gene)|ensemblfungi:SPBC409.05.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0017117"(single-stranded DNA-dependent ATP-dependent DNA helicase complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043224"(nuclear SCF ubiquitin ligase complex)|go:"GO:0043291"(RAVE complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0060542"(regulation of strand invasion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070647"(protein modification by small protein conjugation or removal)|go:"GO:0097602"(cullin family protein binding)|go:"GO:0101026"(mitotic nuclear membrane biogenesis)|reactome:R-SPO-174113|reactome:R-SPO-68949|reactome:R-SPO-8854050|reactome:R-SPO-8951664|reactome:R-SPO-983168|refseq:NP_595455.1|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR001232(SKP1 component)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|mint:Q9Y709|interpro:IPR036296 - - - figure legend:Figure 1B|comment:An anti-skp1 antibody was used to detect the presence of skp1 and the anti-myc antibody showed the presence of pof3-myc with skp1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2007/02/19 2014/10/16 rogid:pGT/etfX8G8yABFJufbEKwKAmHk284812 rogid:XoPbtkSSDN7NGIHiiHBf0tx5nBY284812 intact-crc:5C5CCAF33F48E06B|rigid:gRxgbM85RKyLayLDaz3yMNuEsSE false myc tag:?-? - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O74991 uniprotkb:Q9C107 intact:EBI-1153554|ensemblfungi:"SPCC338.16.1:pep" intact:EBI-1203666|ensemblfungi:"SPAPB1E7.02c.1:pep" psi-mi:pof3_schpo(display_long)|uniprotkb:pof3(gene name)|psi-mi:pof3(display_short)|uniprotkb:SPCC338.16(orf name) psi-mi:mcl1_schpo(display_long)|uniprotkb:mcl1(gene name)|psi-mi:mcl1(display_short)|uniprotkb:SPAPB1E7.02c(orf name)|uniprotkb:slr3(gene name synonym)|uniprotkb:DNA polymerase alpha accessory factor Mcl1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Mamnun et al. (2006) pubmed:16997270|imex:IM-19919 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1203706|imex:IM-19919-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR019734|interpro:IPR036047|ensemblfungi:SPCC338.16(gene)|ensemblfungi:SPCC338.16.1(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000723"(telomere maintenance)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0061806"(regulation of DNA recombination at centromere)|go:"GO:1903464"(negative regulation of mitotic cell cycle DNA replication)|interpro:IPR032675|refseq:NP_588152.1|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR011990(Tetratricopeptide-like helical) refseq:NP_594128.1|interpro:IPR022100|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR024977|mint:Q9C107|ensemblfungi:SPAPB1E7.02c(gene)|ensemblfungi:SPAPB1E7.02c.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0061641"(CENP-A containing chromatin organization)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|interpro:IPR036322 - - - figure legend:Figure 1B and 1C.|comment:Pof3 is shown to interact with Mcl1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2007/02/19 2014/10/16 rogid:pGT/etfX8G8yABFJufbEKwKAmHk284812 rogid:D3mV0rIaeqOhafHjCccHWnTNQgk284812 intact-crc:7F3FC119222A2A07|rigid:Q+jYEAm+3oMddyNWq8+mQDBTWSQ false myc tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)