#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P03069 uniprotkb:P03069 intact:EBI-7450|uniprotkb:P03068|uniprotkb:Q70D88|uniprotkb:Q70D91|uniprotkb:Q70D96|uniprotkb:Q70D99|uniprotkb:Q70DA0|uniprotkb:Q96UT3|uniprotkb:D3DLN9|ensemblfungi:YEL009C intact:EBI-7450|uniprotkb:P03068|uniprotkb:Q70D88|uniprotkb:Q70D91|uniprotkb:Q70D96|uniprotkb:Q70D99|uniprotkb:Q70DA0|uniprotkb:Q96UT3|uniprotkb:D3DLN9|ensemblfungi:YEL009C psi-mi:gcn4_yeast(display_long)|uniprotkb:ARG9(gene name synonym)|uniprotkb:GCN4(gene name)|psi-mi:GCN4(display_short)|uniprotkb:AAS3(gene name synonym)|uniprotkb:Amino acid biosynthesis regulatory protein(gene name synonym)|uniprotkb:AAS101(gene name synonym)|uniprotkb:General control protein GCN4(gene name synonym)|uniprotkb:YEL009C(locus name) psi-mi:gcn4_yeast(display_long)|uniprotkb:ARG9(gene name synonym)|uniprotkb:GCN4(gene name)|psi-mi:GCN4(display_short)|uniprotkb:AAS3(gene name synonym)|uniprotkb:Amino acid biosynthesis regulatory protein(gene name synonym)|uniprotkb:AAS101(gene name synonym)|uniprotkb:General control protein GCN4(gene name synonym)|uniprotkb:YEL009C(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1253893|imex:IM-23771-1|dip:DIP-57036E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) sgd:S000000735|refseq:NP_010907.3|mint:P03069|dip:DIP-591N|ensemblfungi:YEL009C(gene)|ensemblfungi:YEL009C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001080"(nitrogen catabolite activation of transcription from RNA polymerase II promoter)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061412"(positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|go:"GO:1990139"(protein localization to nuclear periphery)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:1CE9|rcsb pdb:1DGC|rcsb pdb:1ENV|rcsb pdb:1FAV|rcsb pdb:1FMH|rcsb pdb:1GCL|rcsb pdb:1GCM|rcsb pdb:1GK6|rcsb pdb:1GZL|rcsb pdb:1IHQ|rcsb pdb:1IJ0|rcsb pdb:1IJ1|rcsb pdb:1IJ2|rcsb pdb:1IJ3|rcsb pdb:1KQL|rcsb pdb:1LD4|rcsb pdb:1LLM|rcsb pdb:1NKN|rcsb pdb:1PIQ|rcsb pdb:1RB4|rcsb pdb:1RB5|rcsb pdb:1RB6|rcsb pdb:1SWI|rcsb pdb:1TMZ|rcsb pdb:1UNT|rcsb pdb:1UNU|rcsb pdb:1UNV|rcsb pdb:1UNW|rcsb pdb:1UNX|rcsb pdb:1UNY|rcsb pdb:1UNZ|rcsb pdb:1UO0|rcsb pdb:1UO1|rcsb pdb:1UO2|rcsb pdb:1UO3|rcsb pdb:1UO4|rcsb pdb:1UO5|rcsb pdb:1W5G|rcsb pdb:1W5H|rcsb pdb:1W5I|rcsb pdb:1W5J|rcsb pdb:1W5K|rcsb pdb:1W5L|rcsb pdb:1YSA|rcsb pdb:1ZII|rcsb pdb:1ZIJ|rcsb pdb:1ZIK|rcsb pdb:1ZIL|rcsb pdb:1ZIM|rcsb pdb:1ZTA|rcsb pdb:2AHP|rcsb pdb:2B1F|rcsb pdb:2B22|rcsb pdb:2BNI|rcsb pdb:2CCE|rcsb pdb:2CCF|rcsb pdb:2CCN|rcsb pdb:2D3E|rcsb pdb:2DGC|rcsb pdb:2EFR|rcsb pdb:2EFS|rcsb pdb:2G9J|rcsb pdb:2HY6|rcsb pdb:2IPZ|rcsb pdb:2K8X|rcsb pdb:2LPB|rcsb pdb:2N9B|rcsb pdb:2NRN|rcsb pdb:2O7H|rcsb pdb:2OVN|rcsb pdb:2VKY|rcsb pdb:2VNL|rcsb pdb:2WG5|rcsb pdb:2WG6|rcsb pdb:2WPY|rcsb pdb:2WPZ|rcsb pdb:2WQ0|rcsb pdb:2WQ1|rcsb pdb:2WQ2|rcsb pdb:2WQ3|rcsb pdb:2YNY|rcsb pdb:2YNZ|rcsb pdb:2YO0|rcsb pdb:2YO1|rcsb pdb:2YO2|rcsb pdb:2YO3|rcsb pdb:2Z5H|rcsb pdb:2Z5I|rcsb pdb:2ZTA|rcsb pdb:3AZD|rcsb pdb:3BAS|rcsb pdb:3BAT|rcsb pdb:3CK4|rcsb pdb:3CRP|rcsb pdb:3G9R|rcsb pdb:3GJP|rcsb pdb:3I1G|rcsb pdb:3I5C|rcsb pdb:3K7Z|rcsb pdb:3M48|rcsb pdb:3P8M|rcsb pdb:3ZMF|rcsb pdb:4C46|rcsb pdb:4DMD|rcsb pdb:4G2K|rcsb pdb:4HU5|rcsb pdb:4HU6|rcsb pdb:4NIZ|rcsb pdb:4NJ0|rcsb pdb:4NJ1|rcsb pdb:4NJ2|rcsb pdb:4OWI|rcsb pdb:4TL1|rcsb pdb:5APP|rcsb pdb:5APQ|rcsb pdb:5APS|rcsb pdb:5APT|rcsb pdb:5APU|rcsb pdb:5APV|rcsb pdb:5APW|rcsb pdb:5APX|rcsb pdb:5APY|rcsb pdb:5APZ|rcsb pdb:5IEW|rcsb pdb:5IIR|rcsb pdb:5IIV|rcsb pdb:5KHT|rcsb pdb:6E52|rcsb pdb:6E95|rcsb pdb:6H9M|rcsb pdb:6HN4|rcsb pdb:6HN5|rcsb pdb:6O2E|rcsb pdb:6O2F|rcsb pdb:6PSA|rcsb pdb:6UT2|rcsb pdb:6VWG|rcsb pdb:6VWH|rcsb pdb:6VWI|rcsb pdb:6VWJ|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-450341 sgd:S000000735|refseq:NP_010907.3|mint:P03069|dip:DIP-591N|ensemblfungi:YEL009C(gene)|ensemblfungi:YEL009C_mRNA(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001080"(nitrogen catabolite activation of transcription from RNA polymerase II promoter)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0008652"(cellular amino acid biosynthetic process)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010691"(negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036278"(positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061412"(positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903833"(positive regulation of cellular response to amino acid starvation)|go:"GO:1990139"(protein localization to nuclear periphery)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|rcsb pdb:1CE9|rcsb pdb:1DGC|rcsb pdb:1ENV|rcsb pdb:1FAV|rcsb pdb:1FMH|rcsb pdb:1GCL|rcsb pdb:1GCM|rcsb pdb:1GK6|rcsb pdb:1GZL|rcsb pdb:1IHQ|rcsb pdb:1IJ0|rcsb pdb:1IJ1|rcsb pdb:1IJ2|rcsb pdb:1IJ3|rcsb pdb:1KQL|rcsb pdb:1LD4|rcsb pdb:1LLM|rcsb pdb:1NKN|rcsb pdb:1PIQ|rcsb pdb:1RB4|rcsb pdb:1RB5|rcsb pdb:1RB6|rcsb pdb:1SWI|rcsb pdb:1TMZ|rcsb pdb:1UNT|rcsb pdb:1UNU|rcsb pdb:1UNV|rcsb pdb:1UNW|rcsb pdb:1UNX|rcsb pdb:1UNY|rcsb pdb:1UNZ|rcsb pdb:1UO0|rcsb pdb:1UO1|rcsb pdb:1UO2|rcsb pdb:1UO3|rcsb pdb:1UO4|rcsb pdb:1UO5|rcsb pdb:1W5G|rcsb pdb:1W5H|rcsb pdb:1W5I|rcsb pdb:1W5J|rcsb pdb:1W5K|rcsb pdb:1W5L|rcsb pdb:1YSA|rcsb pdb:1ZII|rcsb pdb:1ZIJ|rcsb pdb:1ZIK|rcsb pdb:1ZIL|rcsb pdb:1ZIM|rcsb pdb:1ZTA|rcsb pdb:2AHP|rcsb pdb:2B1F|rcsb pdb:2B22|rcsb pdb:2BNI|rcsb pdb:2CCE|rcsb pdb:2CCF|rcsb pdb:2CCN|rcsb pdb:2D3E|rcsb pdb:2DGC|rcsb pdb:2EFR|rcsb pdb:2EFS|rcsb pdb:2G9J|rcsb pdb:2HY6|rcsb pdb:2IPZ|rcsb pdb:2K8X|rcsb pdb:2LPB|rcsb pdb:2N9B|rcsb pdb:2NRN|rcsb pdb:2O7H|rcsb pdb:2OVN|rcsb pdb:2VKY|rcsb pdb:2VNL|rcsb pdb:2WG5|rcsb pdb:2WG6|rcsb pdb:2WPY|rcsb pdb:2WPZ|rcsb pdb:2WQ0|rcsb pdb:2WQ1|rcsb pdb:2WQ2|rcsb pdb:2WQ3|rcsb pdb:2YNY|rcsb pdb:2YNZ|rcsb pdb:2YO0|rcsb pdb:2YO1|rcsb pdb:2YO2|rcsb pdb:2YO3|rcsb pdb:2Z5H|rcsb pdb:2Z5I|rcsb pdb:2ZTA|rcsb pdb:3AZD|rcsb pdb:3BAS|rcsb pdb:3BAT|rcsb pdb:3CK4|rcsb pdb:3CRP|rcsb pdb:3G9R|rcsb pdb:3GJP|rcsb pdb:3I1G|rcsb pdb:3I5C|rcsb pdb:3K7Z|rcsb pdb:3M48|rcsb pdb:3P8M|rcsb pdb:3ZMF|rcsb pdb:4C46|rcsb pdb:4DMD|rcsb pdb:4G2K|rcsb pdb:4HU5|rcsb pdb:4HU6|rcsb pdb:4NIZ|rcsb pdb:4NJ0|rcsb pdb:4NJ1|rcsb pdb:4NJ2|rcsb pdb:4OWI|rcsb pdb:4TL1|rcsb pdb:5APP|rcsb pdb:5APQ|rcsb pdb:5APS|rcsb pdb:5APT|rcsb pdb:5APU|rcsb pdb:5APV|rcsb pdb:5APW|rcsb pdb:5APX|rcsb pdb:5APY|rcsb pdb:5APZ|rcsb pdb:5IEW|rcsb pdb:5IIR|rcsb pdb:5IIV|rcsb pdb:5KHT|rcsb pdb:6E52|rcsb pdb:6E95|rcsb pdb:6H9M|rcsb pdb:6HN4|rcsb pdb:6HN5|rcsb pdb:6O2E|rcsb pdb:6O2F|rcsb pdb:6PSA|rcsb pdb:6UT2|rcsb pdb:6VWG|rcsb pdb:6VWH|rcsb pdb:6VWI|rcsb pdb:6VWJ|reactome:R-SCE-2559580|reactome:R-SCE-2871796|reactome:R-SCE-450341 psi-mi:"MI:0465"(dip) crc64:2ED1B8E35D509578 crc64:2ED1B8E35D509578 figure legend:Fig. 3, 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:1772(mycsm)|taxid:1772(Mycobacterium smegmatis) - 2007/05/17 2017/06/30 rogid:MFj9JcYccWKTayvnuaN95djsHd0559292 rogid:MFj9JcYccWKTayvnuaN95djsHd0559292 intact-crc:91DDB4197B36B6CA|rigid:q9aALwC1bPcZROqvbqKmvdK/TwY false tag:c-c tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WGL3 uniprotkb:P9WGN1 intact:EBI-1253898|uniprotkb:L0T881|uniprotkb:P96372 intact:EBI-15183611|uniprotkb:L0T8E7|uniprotkb:P96373|uniprotkb:Q7D8Z1 psi-mi:kdpd_myctu(display_long)|uniprotkb:kdpD(gene name)|psi-mi:kdpD(display_short)|uniprotkb:Rv1028c(locus name)|uniprotkb:MTCY10G2.21(orf name) psi-mi:kdpe_myctu(display_long)|uniprotkb:kdpE(gene name)|psi-mi:kdpE(display_short)|uniprotkb:Rv1027c(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1253920|imex:IM-23771-2|dip:DIP-197854E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_215544.1|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR003661(Signal transduction histidine kinase, subgroup 1, dimerisation and phosphoacceptor region)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR003852(Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal)|interpro:IPR006016(UspA)|interpro:IPR027417|interpro:IPR025201|refseq:WP_003915886.1|interpro:IPR038318|interpro:IPR036097|interpro:IPR036890|go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0009593"(detection of chemical stimulus)|go:"GO:0016021"(integral component of membrane) go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0032993"(protein-DNA complex)|refseq:NP_215543.1|refseq:WP_003405305.1|interpro:IPR011006(CheY-like)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR036388|interpro:IPR039420 psi-mi:"MI:0465"(dip) - - figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:1772(mycsm)|taxid:1772(Mycobacterium smegmatis) - 2007/05/17 2017/06/30 rogid:oAeVoqe+PrxrlXMPXIlkubeiUP083332 rogid:fazCd7efw39LH0DYGKBr1x1jkhI83332 intact-crc:D37F5D7F5FBC88CA|rigid:VqugiKUfZfmpKTup9yUlZYByUWo false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WNK7 uniprotkb:P9WNK5 intact:EBI-1253925|uniprotkb:F2GDN6|uniprotkb:Q540D8|uniprotkb:O84901|uniprotkb:Q57165|uniprotkb:P0A564 intact:EBI-1253936|uniprotkb:O69739|uniprotkb:L0TDT9|uniprotkb:P0A566 psi-mi:esxa_myctu(display_long)|uniprotkb:esxA(gene name)|psi-mi:esxA(display_short)|uniprotkb:esaT6(gene name synonym)|uniprotkb:Rv3875(locus name)|uniprotkb:MTV027.10(orf name)|uniprotkb:ESAT-6(gene name synonym) psi-mi:esxb_myctu(display_long)|uniprotkb:esxB(gene name)|psi-mi:esxB(display_short)|uniprotkb:cfp10(gene name synonym)|uniprotkb:lhp(gene name synonym)|uniprotkb:mtsA10(gene name synonym)|uniprotkb:Rv3874(locus name)|uniprotkb:MTV027.09(orf name)|uniprotkb:10 kDa culture filtrate antigen CFP-10(gene name synonym)|uniprotkb:Secreted antigenic protein MTSA-10(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1253948|imex:IM-23771-7|dip:DIP-197855E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_178023.1|refseq:WP_003399963.1|mint:P9WNK7|dip:DIP-61227N|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|go:"GO:0052027"(modulation by symbiont of host signal transduction pathway)|go:"GO:0052083"(suppression by symbiont of host cell-mediated immune response)|go:"GO:0052085"(suppression by symbiont of host T-cell mediated immune response)|interpro:IPR010310(Protein of unknown function DUF909)|interpro:IPR036689|rcsb pdb:1WA8|rcsb pdb:3FAV|reactome:R-HSA-9636667|reactome:R-HSA-9637628 refseq:NP_218391.1|interpro:IPR010310(Protein of unknown function DUF909)|refseq:WP_003399940.1|mint:P9WNK5|interpro:IPR036689|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|rcsb pdb:1WA8|rcsb pdb:3FAV|rcsb pdb:6J19 psi-mi:"MI:0465"(dip) - - figure legend:Fig. 3, 4B, 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:1772(mycsm)|taxid:1772(Mycobacterium smegmatis) - 2007/05/17 2017/06/30 rogid:ZHAEE5EVBqthtYz3uzNnohFtr3Q83332 rogid:vmB4BvNHEG7Jq9tk4PooRd2yYHE83332 intact-crc:97834E5DCE941E7A|rigid:Eem0dlTiZaTm9pLwnqA+/vpFA4s false tag:c-c tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WNK7 uniprotkb:P9WNK5 intact:EBI-1253925|uniprotkb:F2GDN6|uniprotkb:Q540D8|uniprotkb:O84901|uniprotkb:Q57165|uniprotkb:P0A564 intact:EBI-1253936|uniprotkb:O69739|uniprotkb:L0TDT9|uniprotkb:P0A566 psi-mi:esxa_myctu(display_long)|uniprotkb:esxA(gene name)|psi-mi:esxA(display_short)|uniprotkb:esaT6(gene name synonym)|uniprotkb:Rv3875(locus name)|uniprotkb:MTV027.10(orf name)|uniprotkb:ESAT-6(gene name synonym) psi-mi:esxb_myctu(display_long)|uniprotkb:esxB(gene name)|psi-mi:esxB(display_short)|uniprotkb:cfp10(gene name synonym)|uniprotkb:lhp(gene name synonym)|uniprotkb:mtsA10(gene name synonym)|uniprotkb:Rv3874(locus name)|uniprotkb:MTV027.09(orf name)|uniprotkb:10 kDa culture filtrate antigen CFP-10(gene name synonym)|uniprotkb:Secreted antigenic protein MTSA-10(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1253955|imex:IM-23771-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_178023.1|refseq:WP_003399963.1|mint:P9WNK7|dip:DIP-61227N|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|go:"GO:0052027"(modulation by symbiont of host signal transduction pathway)|go:"GO:0052083"(suppression by symbiont of host cell-mediated immune response)|go:"GO:0052085"(suppression by symbiont of host T-cell mediated immune response)|interpro:IPR010310(Protein of unknown function DUF909)|interpro:IPR036689|rcsb pdb:1WA8|rcsb pdb:3FAV|reactome:R-HSA-9636667|reactome:R-HSA-9637628 refseq:NP_218391.1|interpro:IPR010310(Protein of unknown function DUF909)|refseq:WP_003399940.1|mint:P9WNK5|interpro:IPR036689|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|rcsb pdb:1WA8|rcsb pdb:3FAV|rcsb pdb:6J19 - - - figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:1772(mycsm)|taxid:1772(Mycobacterium smegmatis) - 2007/05/17 2017/06/30 rogid:ZHAEE5EVBqthtYz3uzNnohFtr3Q83332 rogid:vmB4BvNHEG7Jq9tk4PooRd2yYHE83332 intact-crc:1445C5889516C369|rigid:Eem0dlTiZaTm9pLwnqA+/vpFA4s false tag:n-n tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WMF9 uniprotkb:P9WGK3 intact:EBI-15183688|uniprotkb:L0TBX9|uniprotkb:P95193|uniprotkb:Q79CX8|uniprotkb:Q7D625 intact:EBI-15183642|uniprotkb:L0TBM4|uniprotkb:P95194|uniprotkb:Q79CX7|uniprotkb:Q7D626 psi-mi:devr_myctu(display_long)|uniprotkb:devR(gene name)|psi-mi:devR(display_short)|uniprotkb:dosR(gene name synonym)|uniprotkb:Rv3133c(locus name) psi-mi:devs_myctu(display_long)|uniprotkb:devS(gene name)|psi-mi:devS(display_short)|uniprotkb:dosS(gene name synonym)|uniprotkb:Rv3132c(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1253966|imex:IM-23771-9|dip:DIP-197856E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0022611"(dormancy process)|go:"GO:0044161"(host cell cytoplasmic vesicle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072493"(host cell endosome lumen)|refseq:NP_217649.1|refseq:WP_003416369.1|rcsb pdb:1ZLJ|rcsb pdb:1ZLK|rcsb pdb:3C3W|rcsb pdb:3C57|interpro:IPR011006(CheY-like)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR000792(Bacterial regulatory protein, LuxR) go:"GO:0000155"(phosphorelay sensor kinase activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019825"(oxygen binding)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0020037"(heme binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051776"(detection of redox state)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0051775"(response to redox state)|refseq:NP_217648.1|refseq:WP_003899933.1|rcsb pdb:2W3D|rcsb pdb:2W3E|rcsb pdb:2W3F|rcsb pdb:2W3G|rcsb pdb:2W3H|rcsb pdb:2Y79|rcsb pdb:3ZXO|rcsb pdb:4YNR|rcsb pdb:4YOF|interpro:IPR003018(GAF)|interpro:IPR029016|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR011712(Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor region)|rcsb pdb:2Y8H|interpro:IPR036890 psi-mi:"MI:0465"(dip) - - figure legend:Fig. 4B, 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:1772(mycsm)|taxid:1772(Mycobacterium smegmatis) - 2007/05/17 2017/06/30 rogid:xJsYvrP8nQ4NYHxnnQ+YzoBQjn083332 rogid:sbzczw500tQ+TCRAC3kR3Xd+zIk83332 intact-crc:02C20B57C456510C|rigid:Zegceuf0Qk045h13n2xMgYsKN1I false tag:c-c tag:c-c - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WNK5 uniprotkb:P9WNK7 intact:EBI-1253936|uniprotkb:O69739|uniprotkb:L0TDT9|uniprotkb:P0A566 intact:EBI-1253925|uniprotkb:F2GDN6|uniprotkb:Q540D8|uniprotkb:O84901|uniprotkb:Q57165|uniprotkb:P0A564 psi-mi:esxb_myctu(display_long)|uniprotkb:esxB(gene name)|psi-mi:esxB(display_short)|uniprotkb:cfp10(gene name synonym)|uniprotkb:lhp(gene name synonym)|uniprotkb:mtsA10(gene name synonym)|uniprotkb:Rv3874(locus name)|uniprotkb:MTV027.09(orf name)|uniprotkb:10 kDa culture filtrate antigen CFP-10(gene name synonym)|uniprotkb:Secreted antigenic protein MTSA-10(gene name synonym) psi-mi:esxa_myctu(display_long)|uniprotkb:esxA(gene name)|psi-mi:esxA(display_short)|uniprotkb:esaT6(gene name synonym)|uniprotkb:Rv3875(locus name)|uniprotkb:MTV027.10(orf name)|uniprotkb:ESAT-6(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1253997|imex:IM-23771-16 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_218391.1|interpro:IPR010310(Protein of unknown function DUF909)|refseq:WP_003399940.1|mint:P9WNK5|interpro:IPR036689|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|rcsb pdb:1WA8|rcsb pdb:3FAV|rcsb pdb:6J19 refseq:YP_178023.1|refseq:WP_003399963.1|mint:P9WNK7|dip:DIP-61227N|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|go:"GO:0052027"(modulation by symbiont of host signal transduction pathway)|go:"GO:0052083"(suppression by symbiont of host cell-mediated immune response)|go:"GO:0052085"(suppression by symbiont of host T-cell mediated immune response)|interpro:IPR010310(Protein of unknown function DUF909)|interpro:IPR036689|rcsb pdb:1WA8|rcsb pdb:3FAV|reactome:R-HSA-9636667|reactome:R-HSA-9637628 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:1772(mycsm)|taxid:1772(Mycobacterium smegmatis) - 2007/05/17 2017/06/30 rogid:vmB4BvNHEG7Jq9tk4PooRd2yYHE83332 rogid:ZHAEE5EVBqthtYz3uzNnohFtr3Q83332 intact-crc:C6D7972C559AC2E0|rigid:Eem0dlTiZaTm9pLwnqA+/vpFA4s false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:I6XVZ6 uniprotkb:P9WNK5 intact:EBI-15183739 intact:EBI-1253936|uniprotkb:O69739|uniprotkb:L0TDT9|uniprotkb:P0A566 psi-mi:i6xvz6_myctu(display_long)|uniprotkb:Rv0686(locus name) psi-mi:esxb_myctu(display_long)|uniprotkb:esxB(gene name)|psi-mi:esxB(display_short)|uniprotkb:cfp10(gene name synonym)|uniprotkb:lhp(gene name synonym)|uniprotkb:mtsA10(gene name synonym)|uniprotkb:Rv3874(locus name)|uniprotkb:MTV027.09(orf name)|uniprotkb:10 kDa culture filtrate antigen CFP-10(gene name synonym)|uniprotkb:Secreted antigenic protein MTSA-10(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1254008|imex:IM-23771-14|dip:DIP-197857E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|refseq:NP_215200.1|refseq:WP_003403465.1 refseq:NP_218391.1|interpro:IPR010310(Protein of unknown function DUF909)|refseq:WP_003399940.1|mint:P9WNK5|interpro:IPR036689|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|rcsb pdb:1WA8|rcsb pdb:3FAV|rcsb pdb:6J19 psi-mi:"MI:0465"(dip) - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:1772(mycsm)|taxid:1772(Mycobacterium smegmatis) - 2007/05/17 2017/06/30 rogid:TyZgrZnKLiCZW1nsC/yj3JAIlMo83332 rogid:vmB4BvNHEG7Jq9tk4PooRd2yYHE83332 intact-crc:B538A123296DD6EA|rigid:5RbIz7re9EwJWExt/OywVVhTscc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P9WNA1 uniprotkb:P9WNK5 intact:EBI-1254013|uniprotkb:O06226|uniprotkb:L0TBG9|uniprotkb:P64168 intact:EBI-1253936|uniprotkb:O69739|uniprotkb:L0TDT9|uniprotkb:P0A566 psi-mi:ftsq_myctu(display_long)|uniprotkb:ftsQ(gene name)|psi-mi:ftsQ(display_short)|uniprotkb:Rv2151c(locus name)|uniprotkb:MTCY270.17(orf name) psi-mi:esxb_myctu(display_long)|uniprotkb:esxB(gene name)|psi-mi:esxB(display_short)|uniprotkb:cfp10(gene name synonym)|uniprotkb:lhp(gene name synonym)|uniprotkb:mtsA10(gene name synonym)|uniprotkb:Rv3874(locus name)|uniprotkb:MTV027.09(orf name)|uniprotkb:10 kDa culture filtrate antigen CFP-10(gene name synonym)|uniprotkb:Secreted antigenic protein MTSA-10(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1254024|imex:IM-23771-5|dip:DIP-197859E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005548(Cell division protein FtsQ)|interpro:IPR013685(Polypeptide-transport-associated, FtsQ-type)|refseq:NP_216667.1|interpro:IPR026579|refseq:WP_003411157.1|interpro:IPR034746|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|go:"GO:0090529"(cell septum assembly) refseq:NP_218391.1|interpro:IPR010310(Protein of unknown function DUF909)|refseq:WP_003399940.1|mint:P9WNK5|interpro:IPR036689|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|rcsb pdb:1WA8|rcsb pdb:3FAV|rcsb pdb:6J19 psi-mi:"MI:0465"(dip) - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:1772(mycsm)|taxid:1772(Mycobacterium smegmatis) - 2007/05/17 2017/06/30 rogid:5cRoJrbSTzguVDoQq+wz5036kME83332 rogid:vmB4BvNHEG7Jq9tk4PooRd2yYHE83332 intact-crc:B94E6741BA1248EF|rigid:Kt6pe7ZuOHmMttdlbBhwOwVulyA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P9WPC9 uniprotkb:P9WNK5 intact:EBI-1254029|uniprotkb:O06286|uniprotkb:L0TD96|uniprotkb:P0A522 intact:EBI-1253936|uniprotkb:O69739|uniprotkb:L0TDT9|uniprotkb:P0A566 psi-mi:clpc1_myctu(display_long)|uniprotkb:clpC1(gene name)|psi-mi:clpC1(display_short)|uniprotkb:MTCY07H7B.26(orf name)|uniprotkb:Rv3596c(locus name) psi-mi:esxb_myctu(display_long)|uniprotkb:esxB(gene name)|psi-mi:esxB(display_short)|uniprotkb:cfp10(gene name synonym)|uniprotkb:lhp(gene name synonym)|uniprotkb:mtsA10(gene name synonym)|uniprotkb:Rv3874(locus name)|uniprotkb:MTV027.09(orf name)|uniprotkb:10 kDa culture filtrate antigen CFP-10(gene name synonym)|uniprotkb:Secreted antigenic protein MTSA-10(gene name synonym) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1254043|imex:IM-23771-10|dip:DIP-197860E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_177995.1|refseq:WP_003419511.1|dip:DIP-61228N|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044183"(protein folding chaperone)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004176(Clp, N-terminal)|interpro:IPR018368|interpro:IPR019489|interpro:IPR027417|interpro:IPR036628|interpro:IPR041546|rcsb pdb:3WDB|rcsb pdb:3WDC|rcsb pdb:3WDD|rcsb pdb:3WDE|rcsb pdb:6CN8|rcsb pdb:6PBA|rcsb pdb:6PBQ|rcsb pdb:6PBS|rcsb pdb:6UCR refseq:NP_218391.1|interpro:IPR010310(Protein of unknown function DUF909)|refseq:WP_003399940.1|mint:P9WNK5|interpro:IPR036689|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|rcsb pdb:1WA8|rcsb pdb:3FAV|rcsb pdb:6J19 psi-mi:"MI:0465"(dip) - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:1772(mycsm)|taxid:1772(Mycobacterium smegmatis) - 2007/05/17 2017/06/30 rogid:FftQCq2T0GhDNaw2VQbrqGH1uz883332 rogid:vmB4BvNHEG7Jq9tk4PooRd2yYHE83332 intact-crc:EC9BB4E931174135|rigid:mTyKxCkNdfogThPtU1326KrkF5g false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P9WNK5 uniprotkb:I6X8D2 intact:EBI-1253936|uniprotkb:O69739|uniprotkb:L0TDT9|uniprotkb:P0A566 intact:EBI-15183747 psi-mi:esxb_myctu(display_long)|uniprotkb:esxB(gene name)|psi-mi:esxB(display_short)|uniprotkb:cfp10(gene name synonym)|uniprotkb:lhp(gene name synonym)|uniprotkb:mtsA10(gene name synonym)|uniprotkb:Rv3874(locus name)|uniprotkb:MTV027.09(orf name)|uniprotkb:10 kDa culture filtrate antigen CFP-10(gene name synonym)|uniprotkb:Secreted antigenic protein MTSA-10(gene name synonym) psi-mi:pks13_myctu(display_long)|uniprotkb:pks13(gene name)|psi-mi:pks13(display_short)|uniprotkb:Rv3800c(locus name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1254064|imex:IM-23771-11|dip:DIP-197861E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_218391.1|interpro:IPR010310(Protein of unknown function DUF909)|refseq:WP_003399940.1|mint:P9WNK5|interpro:IPR036689|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|rcsb pdb:1WA8|rcsb pdb:3FAV|rcsb pdb:6J19 interpro:IPR001227(Acyl transferase region)|rcsb pdb:3TZW|rcsb pdb:3TZX|rcsb pdb:3TZY|rcsb pdb:3TZZ|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0031177"(phosphopantetheine binding)|refseq:NP_218317.1|refseq:WP_003902557.1|interpro:IPR029058|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR032821|interpro:IPR018201|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR020841|interpro:IPR020806|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR001031(Thioesterase)|interpro:IPR016039(Thiolase-like)|rcsb pdb:6C4Q|rcsb pdb:6C4V|interpro:IPR036736|rcsb pdb:5V3W|rcsb pdb:5V3X|rcsb pdb:5V3Y|rcsb pdb:5V3Z|rcsb pdb:5V40|rcsb pdb:5V41|rcsb pdb:5V42|rcsb pdb:5XUO|rcsb pdb:6D8I|rcsb pdb:6D8J psi-mi:"MI:0465"(dip) - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:1772(mycsm)|taxid:1772(Mycobacterium smegmatis) - 2007/05/17 2017/06/30 rogid:vmB4BvNHEG7Jq9tk4PooRd2yYHE83332 rogid:qkvyfPw82srotNohs4mENs4VQew83332 intact-crc:01808BB274C89D1E|rigid:GO+7M6JczamaggT/xdIQR1qx6ic false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P9WNK5 uniprotkb:P9WLG7 intact:EBI-1253936|uniprotkb:O69739|uniprotkb:L0TDT9|uniprotkb:P0A566 intact:EBI-1254069|uniprotkb:Q10522|uniprotkb:L0T987 psi-mi:esxb_myctu(display_long)|uniprotkb:esxB(gene name)|psi-mi:esxB(display_short)|uniprotkb:cfp10(gene name synonym)|uniprotkb:lhp(gene name synonym)|uniprotkb:mtsA10(gene name synonym)|uniprotkb:Rv3874(locus name)|uniprotkb:MTV027.09(orf name)|uniprotkb:10 kDa culture filtrate antigen CFP-10(gene name synonym)|uniprotkb:Secreted antigenic protein MTSA-10(gene name synonym) psi-mi:y2240_myctu(display_long)|uniprotkb:Rv2240c(locus name)|uniprotkb:MTCY427.21c(orf name) psi-mi:"MI:0111"(dihydrofolate reductase reconstruction) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1254075|imex:IM-23771-3|dip:DIP-197858E - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_218391.1|interpro:IPR010310(Protein of unknown function DUF909)|refseq:WP_003399940.1|mint:P9WNK5|interpro:IPR036689|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|rcsb pdb:1WA8|rcsb pdb:3FAV|rcsb pdb:6J19 refseq:NP_216756.2|refseq:WP_003911826.1|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane) psi-mi:"MI:0465"(dip) - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:1772(mycsm)|taxid:1772(Mycobacterium smegmatis) - 2007/05/17 2017/06/30 rogid:vmB4BvNHEG7Jq9tk4PooRd2yYHE83332 rogid:wZiBi+UEk43SNv1DD3y3mMb5pt883332 intact-crc:0780C83E15829BF9|rigid:VdiNB7YgoylKoV3bq6Z0Pv2WgJk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P9WPC9 uniprotkb:P9WNK5 intact:EBI-1254029|uniprotkb:O06286|uniprotkb:L0TD96|uniprotkb:P0A522 intact:EBI-1253936|uniprotkb:O69739|uniprotkb:L0TDT9|uniprotkb:P0A566 psi-mi:clpc1_myctu(display_long)|uniprotkb:clpC1(gene name)|psi-mi:clpC1(display_short)|uniprotkb:MTCY07H7B.26(orf name)|uniprotkb:Rv3596c(locus name) psi-mi:esxb_myctu(display_long)|uniprotkb:esxB(gene name)|psi-mi:esxB(display_short)|uniprotkb:cfp10(gene name synonym)|uniprotkb:lhp(gene name synonym)|uniprotkb:mtsA10(gene name synonym)|uniprotkb:Rv3874(locus name)|uniprotkb:MTV027.09(orf name)|uniprotkb:10 kDa culture filtrate antigen CFP-10(gene name synonym)|uniprotkb:Secreted antigenic protein MTSA-10(gene name synonym) psi-mi:"MI:0018"(two hybrid) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1254132|imex:IM-23771-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_177995.1|refseq:WP_003419511.1|dip:DIP-61228N|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044183"(protein folding chaperone)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004176(Clp, N-terminal)|interpro:IPR018368|interpro:IPR019489|interpro:IPR027417|interpro:IPR036628|interpro:IPR041546|rcsb pdb:3WDB|rcsb pdb:3WDC|rcsb pdb:3WDD|rcsb pdb:3WDE|rcsb pdb:6CN8|rcsb pdb:6PBA|rcsb pdb:6PBQ|rcsb pdb:6PBS|rcsb pdb:6UCR refseq:NP_218391.1|interpro:IPR010310(Protein of unknown function DUF909)|refseq:WP_003399940.1|mint:P9WNK5|interpro:IPR036689|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|rcsb pdb:1WA8|rcsb pdb:3FAV|rcsb pdb:6J19 - - - figure legend:Sup. Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/17 2017/06/30 rogid:FftQCq2T0GhDNaw2VQbrqGH1uz883332 rogid:vmB4BvNHEG7Jq9tk4PooRd2yYHE83332 intact-crc:9BF8F1DD663FF82E|rigid:mTyKxCkNdfogThPtU1326KrkF5g false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WNK5 uniprotkb:P95032 intact:EBI-1253936|uniprotkb:O69739|uniprotkb:L0TDT9|uniprotkb:P0A566 intact:EBI-1254002|uniprotkb:Q7D9F5|uniprotkb:F2GNM7|ensemblbacteria:AAK44940 psi-mi:esxb_myctu(display_long)|uniprotkb:esxB(gene name)|psi-mi:esxB(display_short)|uniprotkb:cfp10(gene name synonym)|uniprotkb:lhp(gene name synonym)|uniprotkb:mtsA10(gene name synonym)|uniprotkb:Rv3874(locus name)|uniprotkb:MTV027.09(orf name)|uniprotkb:10 kDa culture filtrate antigen CFP-10(gene name synonym)|uniprotkb:Secreted antigenic protein MTSA-10(gene name synonym) psi-mi:p95032_mycto(display_long)|uniprotkb:MT0714(locus name) psi-mi:"MI:0018"(two hybrid) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83331(mycto)|taxid:83331("Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1254137|imex:IM-23771-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_218391.1|interpro:IPR010310(Protein of unknown function DUF909)|refseq:WP_003399940.1|mint:P9WNK5|interpro:IPR036689|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|rcsb pdb:1WA8|rcsb pdb:3FAV|rcsb pdb:6J19 refseq:WP_003403465.1|ensemblbacteria:AAK44940(transcript)|ensemblbacteria:MT0714(gene)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane) - - - figure legend:Sup. Fig. 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/17 2017/06/30 rogid:vmB4BvNHEG7Jq9tk4PooRd2yYHE83332 rogid:TyZgrZnKLiCZW1nsC/yj3JAIlMo83331 intact-crc:46BB51E4FE27603A|rigid:xvbQgBjnVxSewLpQFaxYU64mWlI false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WNA1 uniprotkb:P9WNK5 intact:EBI-1254013|uniprotkb:O06226|uniprotkb:L0TBG9|uniprotkb:P64168 intact:EBI-1253936|uniprotkb:O69739|uniprotkb:L0TDT9|uniprotkb:P0A566 psi-mi:ftsq_myctu(display_long)|uniprotkb:ftsQ(gene name)|psi-mi:ftsQ(display_short)|uniprotkb:Rv2151c(locus name)|uniprotkb:MTCY270.17(orf name) psi-mi:esxb_myctu(display_long)|uniprotkb:esxB(gene name)|psi-mi:esxB(display_short)|uniprotkb:cfp10(gene name synonym)|uniprotkb:lhp(gene name synonym)|uniprotkb:mtsA10(gene name synonym)|uniprotkb:Rv3874(locus name)|uniprotkb:MTV027.09(orf name)|uniprotkb:10 kDa culture filtrate antigen CFP-10(gene name synonym)|uniprotkb:Secreted antigenic protein MTSA-10(gene name synonym) psi-mi:"MI:0018"(two hybrid) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1254142|imex:IM-23771-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR005548(Cell division protein FtsQ)|interpro:IPR013685(Polypeptide-transport-associated, FtsQ-type)|refseq:NP_216667.1|interpro:IPR026579|refseq:WP_003411157.1|interpro:IPR034746|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0032153"(cell division site)|go:"GO:0043093"(FtsZ-dependent cytokinesis)|go:"GO:0090529"(cell septum assembly) refseq:NP_218391.1|interpro:IPR010310(Protein of unknown function DUF909)|refseq:WP_003399940.1|mint:P9WNK5|interpro:IPR036689|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|rcsb pdb:1WA8|rcsb pdb:3FAV|rcsb pdb:6J19 - - - figure legend:Fig 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/17 2017/06/30 rogid:5cRoJrbSTzguVDoQq+wz5036kME83332 rogid:vmB4BvNHEG7Jq9tk4PooRd2yYHE83332 intact-crc:9F3E0E69BD12EC04|rigid:Kt6pe7ZuOHmMttdlbBhwOwVulyA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WLG7 uniprotkb:P9WNK5 intact:EBI-1254069|uniprotkb:Q10522|uniprotkb:L0T987 intact:EBI-1253936|uniprotkb:O69739|uniprotkb:L0TDT9|uniprotkb:P0A566 psi-mi:y2240_myctu(display_long)|uniprotkb:Rv2240c(locus name)|uniprotkb:MTCY427.21c(orf name) psi-mi:esxb_myctu(display_long)|uniprotkb:esxB(gene name)|psi-mi:esxB(display_short)|uniprotkb:cfp10(gene name synonym)|uniprotkb:lhp(gene name synonym)|uniprotkb:mtsA10(gene name synonym)|uniprotkb:Rv3874(locus name)|uniprotkb:MTV027.09(orf name)|uniprotkb:10 kDa culture filtrate antigen CFP-10(gene name synonym)|uniprotkb:Secreted antigenic protein MTSA-10(gene name synonym) psi-mi:"MI:0018"(two hybrid) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1254147|imex:IM-23771-20 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_216756.2|refseq:WP_003911826.1|go:"GO:0005576"(extracellular region)|go:"GO:0016021"(integral component of membrane) refseq:NP_218391.1|interpro:IPR010310(Protein of unknown function DUF909)|refseq:WP_003399940.1|mint:P9WNK5|interpro:IPR036689|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|rcsb pdb:1WA8|rcsb pdb:3FAV|rcsb pdb:6J19 - - - figure legend:Sup Fig 7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/05/17 2017/06/30 rogid:wZiBi+UEk43SNv1DD3y3mMb5pt883332 rogid:vmB4BvNHEG7Jq9tk4PooRd2yYHE83332 intact-crc:6B6EDBFCF33B304E|rigid:VdiNB7YgoylKoV3bq6Z0Pv2WgJk false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P9WPC9 uniprotkb:P9WNK5 intact:EBI-1254029|uniprotkb:O06286|uniprotkb:L0TD96|uniprotkb:P0A522 intact:EBI-1253936|uniprotkb:O69739|uniprotkb:L0TDT9|uniprotkb:P0A566 psi-mi:clpc1_myctu(display_long)|uniprotkb:clpC1(gene name)|psi-mi:clpC1(display_short)|uniprotkb:MTCY07H7B.26(orf name)|uniprotkb:Rv3596c(locus name) psi-mi:esxb_myctu(display_long)|uniprotkb:esxB(gene name)|psi-mi:esxB(display_short)|uniprotkb:cfp10(gene name synonym)|uniprotkb:lhp(gene name synonym)|uniprotkb:mtsA10(gene name synonym)|uniprotkb:Rv3874(locus name)|uniprotkb:MTV027.09(orf name)|uniprotkb:10 kDa culture filtrate antigen CFP-10(gene name synonym)|uniprotkb:Secreted antigenic protein MTSA-10(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1254184|imex:IM-23771-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_177995.1|refseq:WP_003419511.1|dip:DIP-61228N|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044183"(protein folding chaperone)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004176(Clp, N-terminal)|interpro:IPR018368|interpro:IPR019489|interpro:IPR027417|interpro:IPR036628|interpro:IPR041546|rcsb pdb:3WDB|rcsb pdb:3WDC|rcsb pdb:3WDD|rcsb pdb:3WDE|rcsb pdb:6CN8|rcsb pdb:6PBA|rcsb pdb:6PBQ|rcsb pdb:6PBS|rcsb pdb:6UCR refseq:NP_218391.1|interpro:IPR010310(Protein of unknown function DUF909)|refseq:WP_003399940.1|mint:P9WNK5|interpro:IPR036689|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|rcsb pdb:1WA8|rcsb pdb:3FAV|rcsb pdb:6J19 - - - figure legend:Sup. Fig. 8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2007/05/17 2017/06/30 rogid:FftQCq2T0GhDNaw2VQbrqGH1uz883332 rogid:vmB4BvNHEG7Jq9tk4PooRd2yYHE83332 intact-crc:80CF03024EC119E0|rigid:mTyKxCkNdfogThPtU1326KrkF5g false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P9WPC9 uniprotkb:P9WNK7 intact:EBI-1254029|uniprotkb:O06286|uniprotkb:L0TD96|uniprotkb:P0A522 intact:EBI-1253925|uniprotkb:F2GDN6|uniprotkb:Q540D8|uniprotkb:O84901|uniprotkb:Q57165|uniprotkb:P0A564 psi-mi:clpc1_myctu(display_long)|uniprotkb:clpC1(gene name)|psi-mi:clpC1(display_short)|uniprotkb:MTCY07H7B.26(orf name)|uniprotkb:Rv3596c(locus name) psi-mi:esxa_myctu(display_long)|uniprotkb:esxA(gene name)|psi-mi:esxA(display_short)|uniprotkb:esaT6(gene name synonym)|uniprotkb:Rv3875(locus name)|uniprotkb:MTV027.10(orf name)|uniprotkb:ESAT-6(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1254192|imex:IM-23771-22 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_177995.1|refseq:WP_003419511.1|dip:DIP-61228N|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044183"(protein folding chaperone)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004176(Clp, N-terminal)|interpro:IPR018368|interpro:IPR019489|interpro:IPR027417|interpro:IPR036628|interpro:IPR041546|rcsb pdb:3WDB|rcsb pdb:3WDC|rcsb pdb:3WDD|rcsb pdb:3WDE|rcsb pdb:6CN8|rcsb pdb:6PBA|rcsb pdb:6PBQ|rcsb pdb:6PBS|rcsb pdb:6UCR refseq:YP_178023.1|refseq:WP_003399963.1|mint:P9WNK7|dip:DIP-61227N|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|go:"GO:0052027"(modulation by symbiont of host signal transduction pathway)|go:"GO:0052083"(suppression by symbiont of host cell-mediated immune response)|go:"GO:0052085"(suppression by symbiont of host T-cell mediated immune response)|interpro:IPR010310(Protein of unknown function DUF909)|interpro:IPR036689|rcsb pdb:1WA8|rcsb pdb:3FAV|reactome:R-HSA-9636667|reactome:R-HSA-9637628 - - - figure legend:Sup. Fig. 8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2007/05/17 2017/06/30 rogid:FftQCq2T0GhDNaw2VQbrqGH1uz883332 rogid:ZHAEE5EVBqthtYz3uzNnohFtr3Q83332 intact-crc:8DAF36B72EC131C0|rigid:7Sq4mNIzBdvm7LgiCFF1g7M9NsE false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:P9WPC9 uniprotkb:P9WPC3 intact:EBI-1254029|uniprotkb:O06286|uniprotkb:L0TD96|uniprotkb:P0A522 intact:EBI-1254199|uniprotkb:O53187|uniprotkb:L0TCE9|uniprotkb:P63783 psi-mi:clpc1_myctu(display_long)|uniprotkb:clpC1(gene name)|psi-mi:clpC1(display_short)|uniprotkb:MTCY07H7B.26(orf name)|uniprotkb:Rv3596c(locus name) psi-mi:clpp2_myctu(display_long)|uniprotkb:clpP2(gene name)|psi-mi:clpP2(display_short)|uniprotkb:Rv2460c(locus name)|uniprotkb:MTV008.16c(orf name)|uniprotkb:Endopeptidase Clp 2(gene name synonym) psi-mi:"MI:0096"(pull down) Singh et al. (2006) pubmed:16844784|imex:IM-23771 taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-1254210|imex:IM-23771-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_177995.1|refseq:WP_003419511.1|dip:DIP-61228N|go:"GO:0005524"(ATP binding)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044183"(protein folding chaperone)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR004176(Clp, N-terminal)|interpro:IPR018368|interpro:IPR019489|interpro:IPR027417|interpro:IPR036628|interpro:IPR041546|rcsb pdb:3WDB|rcsb pdb:3WDC|rcsb pdb:3WDD|rcsb pdb:3WDE|rcsb pdb:6CN8|rcsb pdb:6PBA|rcsb pdb:6PBQ|rcsb pdb:6PBS|rcsb pdb:6UCR refseq:NP_216976.1|interpro:IPR023562|interpro:IPR001907(Peptidase S14, ClpP)|interpro:IPR018215|rcsb pdb:5DZK|rcsb pdb:5E0S|interpro:IPR029045|rcsb pdb:4U0G|interpro:IPR033135|refseq:WP_003412648.1|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0009368"(endopeptidase Clp complex)|go:"GO:0051117"(ATPase binding)|rcsb pdb:6VGK|rcsb pdb:6VGN|rcsb pdb:6VGQ - - - figure legend:Sup. Fig. 8|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2007/05/17 2017/06/30 rogid:FftQCq2T0GhDNaw2VQbrqGH1uz883332 rogid:g+N3YSJbYA0derkhQ+nnJ8Hwfc483332 intact-crc:80E8942A1EE04121|rigid:RPgy6bPJ48QhDRalXN/7H8j7Uho false his tag:n-n - - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)