#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P38960 uniprotkb:Q07921 intact:EBI-18427|uniprotkb:D6VS69|ensemblfungi:YDR082W intact:EBI-35131|uniprotkb:D6VY12|ensemblfungi:YLR010C psi-mi:stn1_yeast(display_long)|uniprotkb:STN1(gene name)|psi-mi:STN1(display_short)|uniprotkb:D4456(orf name)|uniprotkb:YD8554.15(orf name)|uniprotkb:YDR082W(locus name) psi-mi:ten1_yeast(display_long)|uniprotkb:TEN1(gene name)|psi-mi:TEN1(display_short)|uniprotkb:Protein telomeric pathways with STN1(gene name synonym)|uniprotkb:YLR010C(locus name) psi-mi:"MI:0018"(two hybrid) Petreaca et al. (2006) pubmed:16767082|imex:IM-19464 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1556022|imex:IM-19464-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010367.1|sgd:S000002489|ensemblfungi:YDR082W(gene)|ensemblfungi:YDR082W_mRNA(transcript)|go:"GO:0016233"(telomere capping)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0061770"(translation elongation factor binding)|go:"GO:1990879"(CST complex)|interpro:IPR018856|interpro:IPR024263|interpro:IPR038240|rcsb pdb:3K10|rcsb pdb:3KEY|dip:DIP-1230N sgd:S000004000|refseq:NP_013110.1|dip:DIP-5926N|ensemblfungi:YLR010C(gene)|ensemblfungi:YLR010C_mRNA(transcript)|go:"GO:0003711"(transcription elongation regulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016233"(telomere capping)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0061770"(translation elongation factor binding)|go:"GO:1990879"(CST complex) - crc64:61B691C8D4A2E650 crc64:0D8152451821E2CE figure legend:Fig 1a, 1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/16 2014/10/16 rogid:ARXyD+3sq7/gT0WnA5whhA5eIsA559292 rogid:NXyivLmSNmG/aOmYTI8GqsG9nNY559292 intact-crc:9AEF0BCDF71C9157|rigid:Kygtl3iUaieM0rgn6DGJQfcqNlE false sufficient binding region:1-186 - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P32797 uniprotkb:P38960 intact:EBI-4187|uniprotkb:Q07650|uniprotkb:D6VRD4|ensemblfungi:YDL220C intact:EBI-18427|uniprotkb:D6VS69|ensemblfungi:YDR082W psi-mi:cdc13_yeast(display_long)|uniprotkb:CDC13(gene name)|psi-mi:CDC13(display_short)|uniprotkb:YDL220C(locus name) psi-mi:stn1_yeast(display_long)|uniprotkb:STN1(gene name)|psi-mi:STN1(display_short)|uniprotkb:D4456(orf name)|uniprotkb:YD8554.15(orf name)|uniprotkb:YDR082W(locus name) psi-mi:"MI:0018"(two hybrid) Petreaca et al. (2006) pubmed:16767082|imex:IM-19464 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1556029|imex:IM-19464-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010061.1|sgd:S000002379|dip:DIP-1229N|mint:P32797|ensemblfungi:YDL220C(gene)|ensemblfungi:YDL220C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007049"(cell cycle)|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0016233"(telomere capping)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0051301"(cell division)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061770"(translation elongation factor binding)|go:"GO:0071166"(ribonucleoprotein complex localization)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1990879"(CST complex)|interpro:IPR011564(Telomere end binding protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028389|interpro:IPR031749|interpro:IPR040650|interpro:IPR041028|rcsb pdb:1KXL|rcsb pdb:1S40|rcsb pdb:3NWS|rcsb pdb:3NWT|rcsb pdb:3OIP|rcsb pdb:3OIQ|rcsb pdb:4HCE refseq:NP_010367.1|sgd:S000002489|ensemblfungi:YDR082W(gene)|ensemblfungi:YDR082W_mRNA(transcript)|go:"GO:0016233"(telomere capping)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0061770"(translation elongation factor binding)|go:"GO:1990879"(CST complex)|interpro:IPR018856|interpro:IPR024263|interpro:IPR038240|rcsb pdb:3K10|rcsb pdb:3KEY|dip:DIP-1230N - crc64:9FE0AD08520A6F8A crc64:61B691C8D4A2E650 figure legend:Fig 1a, 1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/11/16 2014/10/16 rogid:gEY0/HOYDHm74lrl6CSs1ZGNpkA559292 rogid:ARXyD+3sq7/gT0WnA5whhA5eIsA559292 intact-crc:4E0550FA4C0FA01A|rigid:Nxgp0CSBeiwJxzy1fP7Nl1JvXFA false - sufficient binding region:288-494 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P38960 uniprotkb:P38121 intact:EBI-18427|uniprotkb:D6VS69|ensemblfungi:YDR082W intact:EBI-6111|uniprotkb:D6VPW4|ensemblfungi:YBL035C psi-mi:stn1_yeast(display_long)|uniprotkb:STN1(gene name)|psi-mi:STN1(display_short)|uniprotkb:D4456(orf name)|uniprotkb:YD8554.15(orf name)|uniprotkb:YDR082W(locus name) psi-mi:dpoa2_yeast(display_long)|uniprotkb:DNA polymerase I subunit B(gene name synonym)|uniprotkb:POL12(gene name)|psi-mi:POL12(display_short)|uniprotkb:YBL035C(locus name)|uniprotkb:YBL0414(orf name)|uniprotkb:"DNA polymerase alpha:primase complex p86 subunit"(gene name synonym)|uniprotkb:DNA polymerase-primase complex p74 subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Petreaca et al. (2006) pubmed:16767082|imex:IM-19464 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1556051|imex:IM-19464-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010367.1|sgd:S000002489|ensemblfungi:YDR082W(gene)|ensemblfungi:YDR082W_mRNA(transcript)|go:"GO:0016233"(telomere capping)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0061770"(translation elongation factor binding)|go:"GO:1990879"(CST complex)|interpro:IPR018856|interpro:IPR024263|interpro:IPR038240|rcsb pdb:3K10|rcsb pdb:3KEY|dip:DIP-1230N refseq:NP_009518.1|sgd:S000000131|dip:DIP-2536N|mint:P38121|ensemblfungi:YBL035C(gene)|ensemblfungi:YBL035C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0016233"(telomere capping)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR013627(DNA polymerase alpha, subunit B N-terminal)|interpro:IPR016722(DNA polymerase alpha, subunit B)|rcsb pdb:3FLO|reactome:R-SCE-113501|reactome:R-SCE-68952|reactome:R-SCE-68962|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183 - crc64:61B691C8D4A2E650 crc64:F9F06D12F6979637 figure legend:Fig 4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/16 2014/10/16 rogid:ARXyD+3sq7/gT0WnA5whhA5eIsA559292 rogid:q5lPPAQigZQXvhsRj1HDU3totj4559292 intact-crc:A84449616A218396|rigid:ofhQW2ZGb2A9y9YguI4LNl1fNpk false ha tag:n-n|sufficient binding region:1-186|sufficient binding region:288-494 glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P38960 uniprotkb:P38121 intact:EBI-18427|uniprotkb:D6VS69|ensemblfungi:YDR082W intact:EBI-6111|uniprotkb:D6VPW4|ensemblfungi:YBL035C psi-mi:stn1_yeast(display_long)|uniprotkb:STN1(gene name)|psi-mi:STN1(display_short)|uniprotkb:D4456(orf name)|uniprotkb:YD8554.15(orf name)|uniprotkb:YDR082W(locus name) psi-mi:dpoa2_yeast(display_long)|uniprotkb:DNA polymerase I subunit B(gene name synonym)|uniprotkb:POL12(gene name)|psi-mi:POL12(display_short)|uniprotkb:YBL035C(locus name)|uniprotkb:YBL0414(orf name)|uniprotkb:"DNA polymerase alpha:primase complex p86 subunit"(gene name synonym)|uniprotkb:DNA polymerase-primase complex p74 subunit(gene name synonym) psi-mi:"MI:0096"(pull down) Petreaca et al. (2006) pubmed:16767082|imex:IM-19464 taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-1556074|imex:IM-19464-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_010367.1|sgd:S000002489|ensemblfungi:YDR082W(gene)|ensemblfungi:YDR082W_mRNA(transcript)|go:"GO:0016233"(telomere capping)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0061770"(translation elongation factor binding)|go:"GO:1990879"(CST complex)|interpro:IPR018856|interpro:IPR024263|interpro:IPR038240|rcsb pdb:3K10|rcsb pdb:3KEY|dip:DIP-1230N refseq:NP_009518.1|sgd:S000000131|dip:DIP-2536N|mint:P38121|ensemblfungi:YBL035C(gene)|ensemblfungi:YBL035C_mRNA(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0016233"(telomere capping)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR007185(DNA polymerase alpha/epsilon, subunit B)|interpro:IPR013627(DNA polymerase alpha, subunit B N-terminal)|interpro:IPR016722(DNA polymerase alpha, subunit B)|rcsb pdb:3FLO|reactome:R-SCE-113501|reactome:R-SCE-68952|reactome:R-SCE-68962|reactome:R-SCE-69091|reactome:R-SCE-69166|reactome:R-SCE-69183 - crc64:61B691C8D4A2E650 crc64:F9F06D12F6979637 figure legend:Fig 4d|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2007/11/16 2014/10/16 rogid:ARXyD+3sq7/gT0WnA5whhA5eIsA559292 rogid:q5lPPAQigZQXvhsRj1HDU3totj4559292 intact-crc:70B04474986F3817|rigid:ofhQW2ZGb2A9y9YguI4LNl1fNpk false 35s radiolabel:?-?|sufficient binding region:1-186 glutathione s tranferase tag:n-n - - psi-mi:"MI:0821"(molecular weight estimation by autoradiography) psi-mi:"MI:0821"(molecular weight estimation by autoradiography)