#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q21955	uniprotkb:O45666	intact:EBI-318240|uniprotkb:Q8MPZ3|ensemblmetazoa:R12B2.5a.1|ensemblmetazoa:R12B2.5a.2	intact:EBI-318820|uniprotkb:Q8I4H3|uniprotkb:Q8I4H4|uniprotkb:Q8WQE4|uniprotkb:Q9BJL0|uniprotkb:Q9GTG4|uniprotkb:Q9GTG5|uniprotkb:Q9GTG6|uniprotkb:Q9GTG7|ensemblmetazoa:K10C3.6c.1|ensemblmetazoa:K10C3.6c.2	psi-mi:med15_caeel(display_long)|uniprotkb:R12B2.5(orf name)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:mdt-15(gene name)|psi-mi:mdt-15(display_short)	psi-mi:nhr49_caeel(display_long)|uniprotkb:nhr-49(gene name)|psi-mi:nhr-49(display_short)|uniprotkb:K10C3.6(orf name)	psi-mi:"MI:0018"(two hybrid)	Taubert et al. (2006)	pubmed:16651656|imex:IM-19166	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1534334|imex:IM-19166-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_741151.1|refseq:NP_741152.1|wormbase:R12B2.5a|wormbase:R12B2.5b|ensemblmetazoa:R12B2.5a.1(transcript)|ensemblmetazoa:R12B2.5a.2(transcript)|ensemblmetazoa:WBGene00007016(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0030730"(sequestering of triglyceride)|go:"GO:0040011"(locomotion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR019087|interpro:IPR036529|dip:DIP-38923N	refseq:NP_492612.1|refseq:NP_492613.1|refseq:NP_871798.1|refseq:NP_871799.1|wormbase:K10C3.6a|wormbase:K10C3.6b|wormbase:K10C3.6c|wormbase:K10C3.6d|ensemblmetazoa:K10C3.6c.1(transcript)|ensemblmetazoa:K10C3.6c.2(transcript)|ensemblmetazoa:WBGene00003639(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|dip:DIP-24928N	-	-	-	figure legend:Fig 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/19	2014/10/16	rogid:wYRWaXJbRGmfxIxAPeh+Vn97Fzs6239	rogid:JHC87BlBmcHrqHG4EFbpalGzCtI6239	intact-crc:148FE22A6A4C9175|rigid:O+fQi7KxA0v9WTKuluD0o9O7Vqg	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O44960	uniprotkb:Q21955	intact:EBI-321972|uniprotkb:Q688B5|uniprotkb:Q86PK4|uniprotkb:Q86PK5|uniprotkb:Q86PK6|uniprotkb:D4YW56|uniprotkb:D4YW57|ensemblmetazoa:C45E1.1a.1|ensemblmetazoa:C45E1.1a.2	intact:EBI-318240|uniprotkb:Q8MPZ3|ensemblmetazoa:R12B2.5a.1|ensemblmetazoa:R12B2.5a.2	psi-mi:nhr64_caeel(display_long)|uniprotkb:nhr-64(gene name)|psi-mi:nhr-64(display_short)|uniprotkb:C45E1.1(orf name)	psi-mi:med15_caeel(display_long)|uniprotkb:R12B2.5(orf name)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:mdt-15(gene name)|psi-mi:mdt-15(display_short)	psi-mi:"MI:0018"(two hybrid)	Taubert et al. (2006)	pubmed:16651656|imex:IM-19166	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1534340|imex:IM-19166-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001021042.2|refseq:NP_001021043.2|wormbase:C45E1.1a|wormbase:C45E1.1b|ensemblmetazoa:C45E1.1a.2(transcript)|ensemblmetazoa:WBGene00003654(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000003(Retinoid X receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|ensemblmetazoa:C45E1.1a.1(transcript)|dip:DIP-26511N	refseq:NP_741151.1|refseq:NP_741152.1|wormbase:R12B2.5a|wormbase:R12B2.5b|ensemblmetazoa:R12B2.5a.1(transcript)|ensemblmetazoa:R12B2.5a.2(transcript)|ensemblmetazoa:WBGene00007016(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0030730"(sequestering of triglyceride)|go:"GO:0040011"(locomotion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR019087|interpro:IPR036529|dip:DIP-38923N	-	-	-	figure legend:Fig 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/19	2014/10/16	rogid:RPrua9C4IYwJTznl0giE4khHOZg6239	rogid:wYRWaXJbRGmfxIxAPeh+Vn97Fzs6239	intact-crc:B756432407EDA0F5|rigid:xQmkcSu0U+dNPmxTn8ehOk1dfSk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O45666	uniprotkb:Q21955	intact:EBI-318820|uniprotkb:Q8I4H3|uniprotkb:Q8I4H4|uniprotkb:Q8WQE4|uniprotkb:Q9BJL0|uniprotkb:Q9GTG4|uniprotkb:Q9GTG5|uniprotkb:Q9GTG6|uniprotkb:Q9GTG7|ensemblmetazoa:K10C3.6c.1|ensemblmetazoa:K10C3.6c.2	intact:EBI-318240|uniprotkb:Q8MPZ3|ensemblmetazoa:R12B2.5a.1|ensemblmetazoa:R12B2.5a.2	psi-mi:nhr49_caeel(display_long)|uniprotkb:nhr-49(gene name)|psi-mi:nhr-49(display_short)|uniprotkb:K10C3.6(orf name)	psi-mi:med15_caeel(display_long)|uniprotkb:R12B2.5(orf name)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:mdt-15(gene name)|psi-mi:mdt-15(display_short)	psi-mi:"MI:0018"(two hybrid)	Taubert et al. (2006)	pubmed:16651656|imex:IM-19166	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1534351|imex:IM-19166-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_492612.1|refseq:NP_492613.1|refseq:NP_871798.1|refseq:NP_871799.1|wormbase:K10C3.6a|wormbase:K10C3.6b|wormbase:K10C3.6c|wormbase:K10C3.6d|ensemblmetazoa:K10C3.6c.1(transcript)|ensemblmetazoa:K10C3.6c.2(transcript)|ensemblmetazoa:WBGene00003639(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|dip:DIP-24928N	refseq:NP_741151.1|refseq:NP_741152.1|wormbase:R12B2.5a|wormbase:R12B2.5b|ensemblmetazoa:R12B2.5a.1(transcript)|ensemblmetazoa:R12B2.5a.2(transcript)|ensemblmetazoa:WBGene00007016(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0030730"(sequestering of triglyceride)|go:"GO:0040011"(locomotion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR019087|interpro:IPR036529|dip:DIP-38923N	-	-	-	figure legend:Fig 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/19	2014/10/16	rogid:JHC87BlBmcHrqHG4EFbpalGzCtI6239	rogid:wYRWaXJbRGmfxIxAPeh+Vn97Fzs6239	intact-crc:9CC2279AEE0A01B4|rigid:O+fQi7KxA0v9WTKuluD0o9O7Vqg	false	sufficient binding region:92-476	sufficient binding region:1-124	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O45666	uniprotkb:Q21955	intact:EBI-318820|uniprotkb:Q8I4H3|uniprotkb:Q8I4H4|uniprotkb:Q8WQE4|uniprotkb:Q9BJL0|uniprotkb:Q9GTG4|uniprotkb:Q9GTG5|uniprotkb:Q9GTG6|uniprotkb:Q9GTG7|ensemblmetazoa:K10C3.6c.1|ensemblmetazoa:K10C3.6c.2	intact:EBI-318240|uniprotkb:Q8MPZ3|ensemblmetazoa:R12B2.5a.1|ensemblmetazoa:R12B2.5a.2	psi-mi:nhr49_caeel(display_long)|uniprotkb:nhr-49(gene name)|psi-mi:nhr-49(display_short)|uniprotkb:K10C3.6(orf name)	psi-mi:med15_caeel(display_long)|uniprotkb:R12B2.5(orf name)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:mdt-15(gene name)|psi-mi:mdt-15(display_short)	psi-mi:"MI:0018"(two hybrid)	Taubert et al. (2006)	pubmed:16651656|imex:IM-19166	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	taxid:6239(caeel)|taxid:6239(Caenorhabditis elegans)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-1539554|imex:IM-19166-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_492612.1|refseq:NP_492613.1|refseq:NP_871798.1|refseq:NP_871799.1|wormbase:K10C3.6a|wormbase:K10C3.6b|wormbase:K10C3.6c|wormbase:K10C3.6d|ensemblmetazoa:K10C3.6c.1(transcript)|ensemblmetazoa:K10C3.6c.2(transcript)|ensemblmetazoa:WBGene00003639(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|dip:DIP-24928N	refseq:NP_741151.1|refseq:NP_741152.1|wormbase:R12B2.5a|wormbase:R12B2.5b|ensemblmetazoa:R12B2.5a.1(transcript)|ensemblmetazoa:R12B2.5a.2(transcript)|ensemblmetazoa:WBGene00007016(gene)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002119"(nematode larval development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0030730"(sequestering of triglyceride)|go:"GO:0040011"(locomotion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR019087|interpro:IPR036529|dip:DIP-38923N	-	-	-	figure legend:Fig 1A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/09/19	2014/10/16	rogid:JHC87BlBmcHrqHG4EFbpalGzCtI6239	rogid:wYRWaXJbRGmfxIxAPeh+Vn97Fzs6239	intact-crc:382A3C8B0BD0393D|rigid:O+fQi7KxA0v9WTKuluD0o9O7Vqg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)