#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O64682	-	intact:EBI-1393382|ensemblplants:AT2G34650.1	-	psi-mi:pid_arath(display_long)|uniprotkb:Protein kinase ABRUPTUS(gene name synonym)|uniprotkb:T31E10.1(orf name)|uniprotkb:PID(gene name)|psi-mi:PID(display_short)|uniprotkb:ABR(gene name synonym)|uniprotkb:At2g34650(locus name)	-	psi-mi:"MI:0424"(protein kinase assay)	Zegzouti et al. (2006)	pubmed:16601102|imex:IM-23484	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	-	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-1544378|imex:IM-23484-3	-	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0898"(putative self)	-	psi-mi:"MI:0326"(protein)	-	refseq:NP_181012.1|dip:DIP-39595N|ensemblplants:AT2G34650(gene)|ensemblplants:AT2G34650.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009733"(response to auxin)|go:"GO:0009734"(auxin-activated signaling pathway)|go:"GO:0009926"(auxin polar transport)|go:"GO:0009958"(positive gravitropism)|go:"GO:0009986"(cell surface)|go:"GO:0016301"(kinase activity)|go:"GO:0048766"(root hair initiation)|go:"GO:0048767"(root hair elongation)|go:"GO:0048825"(cotyledon development)|go:"GO:0048827"(phyllome development)|go:"GO:0080167"(response to karrikin)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)	-	-	-	-	figure legend:1C 1D 3C|resulting-ptm:autophosphorylation of PID protein.|stimulant:Increasing levels of Magnesium ions stimulated autophosphorylation of PID|inhibition:Calcium ions|comment:"The authors concluded that \"These data suggest that Ca ions may inhibit PID activity by competitive binding and displacement of the Mg2 ions\"."|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/10/10	2017/06/30	rogid:+BL/fcm5zcowZAVICeglB1UWLPQ3702	-	intact-crc:C8DD9B5A04D4BA47	false	mutation increasing interaction:288-288,290-290|his tag:?-?|mutation disrupting interaction:205-205	-	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	-
uniprotkb:O64682	uniprotkb:Q9XF67	intact:EBI-1393382|ensemblplants:AT2G34650.1	intact:EBI-1103587|intact:EBI-1544407|uniprotkb:Q9LZ74|ensemblplants:AT5G04510.1	psi-mi:pid_arath(display_long)|uniprotkb:Protein kinase ABRUPTUS(gene name synonym)|uniprotkb:T31E10.1(orf name)|uniprotkb:PID(gene name)|psi-mi:PID(display_short)|uniprotkb:ABR(gene name synonym)|uniprotkb:At2g34650(locus name)	psi-mi:pdpk1_arath(display_long)|uniprotkb:PDPK1(gene name)|psi-mi:PDPK1(display_short)|uniprotkb:PDK1(gene name synonym)|uniprotkb:T32M21.110(orf name)|uniprotkb:At5g04510(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Zegzouti et al. (2006)	pubmed:16601102|imex:IM-23484	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-1544423|dip:DIP-67659E|imex:IM-23484-1	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_181012.1|dip:DIP-39595N|ensemblplants:AT2G34650(gene)|ensemblplants:AT2G34650.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009733"(response to auxin)|go:"GO:0009734"(auxin-activated signaling pathway)|go:"GO:0009926"(auxin polar transport)|go:"GO:0009958"(positive gravitropism)|go:"GO:0009986"(cell surface)|go:"GO:0016301"(kinase activity)|go:"GO:0048766"(root hair initiation)|go:"GO:0048767"(root hair elongation)|go:"GO:0048825"(cotyledon development)|go:"GO:0048827"(phyllome development)|go:"GO:0080167"(response to karrikin)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)	refseq:NP_568138.1|ensemblplants:AT5G04510(gene)|ensemblplants:AT5G04510.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR033931|interpro:IPR039046|dip:DIP-39596N	psi-mi:"MI:0465"(dip)	-	-	figure legend:3B, 3C, 4B, Supplementary information Figure 8|comment:"The authors concluded that \"transphosphorylation by PDK1 activates PID through up-regulation of autophosphorylation activity\". In addition that \"PDK1 activates PID by phosphorylating one or more of the serines within the PID activation loop\"."|resulting-ptm:phosphorylation of PID|comment:Time course experiments show that the increase in PDK1-dependent PID autophosphorylation is rapid, with peak levels of activation occurring after 30 min of coincubation|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/10/10	2017/06/30	rogid:+BL/fcm5zcowZAVICeglB1UWLPQ3702	rogid:ldfKQZyuqcwL5f1eLWJz1QYfk0c3702	intact-crc:C58767766BF86ADE|rigid:bzlrvKZqjHdZz0l+THrb/leYdoI	false	glutathione s tranferase tag:?-?|mutation disrupting interaction rate:288-288,290-290|mutation disrupting interaction rate:435-435,438-438	his tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:O64682	uniprotkb:Q9XF67	intact:EBI-1393382|ensemblplants:AT2G34650.1	intact:EBI-1103587|intact:EBI-1544407|uniprotkb:Q9LZ74|ensemblplants:AT5G04510.1	psi-mi:pid_arath(display_long)|uniprotkb:Protein kinase ABRUPTUS(gene name synonym)|uniprotkb:T31E10.1(orf name)|uniprotkb:PID(gene name)|psi-mi:PID(display_short)|uniprotkb:ABR(gene name synonym)|uniprotkb:At2g34650(locus name)	psi-mi:pdpk1_arath(display_long)|uniprotkb:PDPK1(gene name)|psi-mi:PDPK1(display_short)|uniprotkb:PDK1(gene name synonym)|uniprotkb:T32M21.110(orf name)|uniprotkb:At5g04510(locus name)	psi-mi:"MI:0424"(protein kinase assay)	Zegzouti et al. (2006)	pubmed:16601102|imex:IM-23484	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0217"(phosphorylation reaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-1544455|imex:IM-23484-4	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_181012.1|dip:DIP-39595N|ensemblplants:AT2G34650(gene)|ensemblplants:AT2G34650.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009733"(response to auxin)|go:"GO:0009734"(auxin-activated signaling pathway)|go:"GO:0009926"(auxin polar transport)|go:"GO:0009958"(positive gravitropism)|go:"GO:0009986"(cell surface)|go:"GO:0016301"(kinase activity)|go:"GO:0048766"(root hair initiation)|go:"GO:0048767"(root hair elongation)|go:"GO:0048825"(cotyledon development)|go:"GO:0048827"(phyllome development)|go:"GO:0080167"(response to karrikin)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)	refseq:NP_568138.1|ensemblplants:AT5G04510(gene)|ensemblplants:AT5G04510.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR033931|interpro:IPR039046|dip:DIP-39596N	-	-	-	figure legend:5|resulting-ptm:phosphorylation of PID|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/10/10	2017/06/30	rogid:+BL/fcm5zcowZAVICeglB1UWLPQ3702	rogid:ldfKQZyuqcwL5f1eLWJz1QYfk0c3702	intact-crc:EA98AB270C845333|rigid:bzlrvKZqjHdZz0l+THrb/leYdoI	false	glutathione s tranferase tag:?-?	his tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:Q9XF67	uniprotkb:O64682	intact:EBI-1103587|intact:EBI-1544407|uniprotkb:Q9LZ74|ensemblplants:AT5G04510.1	intact:EBI-1393382|ensemblplants:AT2G34650.1	psi-mi:pdpk1_arath(display_long)|uniprotkb:PDPK1(gene name)|psi-mi:PDPK1(display_short)|uniprotkb:PDK1(gene name synonym)|uniprotkb:T32M21.110(orf name)|uniprotkb:At5g04510(locus name)	psi-mi:pid_arath(display_long)|uniprotkb:Protein kinase ABRUPTUS(gene name synonym)|uniprotkb:T31E10.1(orf name)|uniprotkb:PID(gene name)|psi-mi:PID(display_short)|uniprotkb:ABR(gene name synonym)|uniprotkb:At2g34650(locus name)	psi-mi:"MI:0096"(pull down)	Zegzouti et al. (2006)	pubmed:16601102|imex:IM-23484	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	taxid:3702(arath)|taxid:3702("Arabidopsis thaliana (Mouse-ear cress)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-1544399|imex:IM-23484-2|dip:DIP-67659E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_568138.1|ensemblplants:AT5G04510(gene)|ensemblplants:AT5G04510.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR033931|interpro:IPR039046|dip:DIP-39596N	refseq:NP_181012.1|dip:DIP-39595N|ensemblplants:AT2G34650(gene)|ensemblplants:AT2G34650.1(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009733"(response to auxin)|go:"GO:0009734"(auxin-activated signaling pathway)|go:"GO:0009926"(auxin polar transport)|go:"GO:0009958"(positive gravitropism)|go:"GO:0009986"(cell surface)|go:"GO:0016301"(kinase activity)|go:"GO:0048766"(root hair initiation)|go:"GO:0048767"(root hair elongation)|go:"GO:0048825"(cotyledon development)|go:"GO:0048827"(phyllome development)|go:"GO:0080167"(response to karrikin)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)	psi-mi:"MI:0465"(dip)	-	-	figure legend:3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/10/10	2017/06/30	rogid:ldfKQZyuqcwL5f1eLWJz1QYfk0c3702	rogid:+BL/fcm5zcowZAVICeglB1UWLPQ3702	intact-crc:7E4F326510E7B6E9|rigid:bzlrvKZqjHdZz0l+THrb/leYdoI	false	his tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)