#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P35125-3	uniprotkb:P10916	intact:EBI-954590|ensembl:ENSP00000461581	intact:EBI-725770|uniprotkb:Q16123|ensembl:ENSP00000228841	psi-mi:p35125-3(display_long)|uniprotkb:"210(ORF1)"(isoform synonym)|uniprotkb:oncTre210p(isoform synonym)|uniprotkb:USP6(gene name)|psi-mi:USP6(display_short)|uniprotkb:HRP1(gene name synonym)|uniprotkb:TRE2(gene name synonym)|uniprotkb:Deubiquitinating enzyme 6(gene name synonym)|uniprotkb:Proto-oncogene TRE-2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 6(gene name synonym)|uniprotkb:Ubiquitin thioesterase 6(gene name synonym)	psi-mi:mlrv_human(display_long)|uniprotkb:MYL2(gene name)|psi-mi:MYL2(display_short)|uniprotkb:Cardiac myosin light chain 2(gene name synonym)|uniprotkb:MLC2(gene name synonym)|uniprotkb:Myosin light chain 2, slow skeletal/ventricular muscle isoform(gene name synonym)|uniprotkb:Ventricular myosin light chain 2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dechamps et al. (2006)	pubmed:16555005	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1225898	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-954564(ubp6_human)|ensembl:ENSG00000129204(gene)|ensembl:ENST00000572949(transcript)	refseq:NP_000423.2|ensembl:ENSG00000111245(gene)|ensembl:ENST00000228841(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098735"(positive regulation of the force of heart contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:5TBY|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)	-	isoform-comment:Was shown to be tumorigenic in transfected mice and seems not to act as GTPase activating protein.	-	dataset:Cancer - Interactions investigated in the context of cancer	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/04/04	2014/10/16	rogid:BJHzlKX2UFz3FpHeyuCsky/CrOU9606	rogid:n2YsPUkQrzvaH0/De4h+/K5Q8rE9606	intact-crc:BE06BAED4BFD2473|rigid:ulrU7Nzyjjg5Z41nm5wGYMDnIjA	false	sufficient binding region:1-499	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P35125	uniprotkb:Q8N8A2	intact:EBI-954564|uniprotkb:Q15634|uniprotkb:Q86WP6|uniprotkb:Q8IWT4|ensembl:ENSP00000250066|ensembl:ENSP00000460380	intact:EBI-1245329|uniprotkb:Q6P480|uniprotkb:Q86VL5|uniprotkb:Q8IZ72|uniprotkb:Q9UFA4|uniprotkb:Q53SL9|ensembl:ENSP00000282272	psi-mi:ubp6_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 6(gene name synonym)|uniprotkb:Deubiquitinating enzyme 6(gene name synonym)|uniprotkb:Proto-oncogene TRE-2(gene name synonym)|uniprotkb:USP6(gene name)|psi-mi:USP6(display_short)|uniprotkb:TRE2(gene name synonym)|uniprotkb:HRP1(gene name synonym)|uniprotkb:Ubiquitin thioesterase 6(gene name synonym)	psi-mi:anr44_human(display_long)|uniprotkb:ANKRD44(gene name)|psi-mi:ANKRD44(display_short)|uniprotkb:Ankyrin repeat domain-containing protein 44(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Dechamps et al. (2006)	pubmed:16555005	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1225912	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004496.2|ensembl:ENST00000250066(transcript)|ensembl:ENST00000574788(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0055037"(recycling endosome)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR035969|interpro:IPR038765|interpro:IPR028889|ensembl:ENSG00000129204(gene)|refseq:NP_001291213.1|refseq:XP_011522352.1|refseq:XP_011522353.1|refseq:XP_011522354.1|refseq:XP_011522355.1|refseq:XP_011522356.1|refseq:XP_011522357.1|refseq:XP_011522358.1|refseq:XP_011522361.1|refseq:XP_016880779.1	refseq:NP_001182073.1|refseq:NP_710181.2|refseq:XP_005247005.1|ensembl:ENSG00000065413(gene)|ensembl:ENST00000282272(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q8N8A2	-	-	-	caution:The authors specify the protein LOC91526 is 919 aa but the longest UniProtKB entry is 944 aa.|dataset:Cancer - Interactions investigated in the context of cancer	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/04/04	2014/10/16	rogid:EjN7POQXOUGbHphIDgTYYBqptJE9606	rogid:Vi+efSZ2F/weEJsGibCJCwhwlXs9606	intact-crc:DCCB5F1731166663|rigid:wgqe7NRQYFTw2aPayUe8MfEu9Dk	false	sufficient binding region:1-499	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P10916	uniprotkb:P35125-3	intact:EBI-725770|uniprotkb:Q16123|ensembl:ENSP00000228841	intact:EBI-954590|ensembl:ENSP00000461581	psi-mi:mlrv_human(display_long)|uniprotkb:MYL2(gene name)|psi-mi:MYL2(display_short)|uniprotkb:Cardiac myosin light chain 2(gene name synonym)|uniprotkb:MLC2(gene name synonym)|uniprotkb:Myosin light chain 2, slow skeletal/ventricular muscle isoform(gene name synonym)|uniprotkb:Ventricular myosin light chain 2(gene name synonym)	psi-mi:p35125-3(display_long)|uniprotkb:"210(ORF1)"(isoform synonym)|uniprotkb:oncTre210p(isoform synonym)|uniprotkb:USP6(gene name)|psi-mi:USP6(display_short)|uniprotkb:HRP1(gene name synonym)|uniprotkb:TRE2(gene name synonym)|uniprotkb:Deubiquitinating enzyme 6(gene name synonym)|uniprotkb:Proto-oncogene TRE-2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 6(gene name synonym)|uniprotkb:Ubiquitin thioesterase 6(gene name synonym)	psi-mi:"MI:0096"(pull down)	Dechamps et al. (2006)	pubmed:16555005	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1225934	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000423.2|ensembl:ENSG00000111245(gene)|ensembl:ENST00000228841(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098735"(positive regulation of the force of heart contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:5TBY|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)	intact:EBI-954564(ubp6_human)|ensembl:ENSG00000129204(gene)|ensembl:ENST00000572949(transcript)	-	-	isoform-comment:Was shown to be tumorigenic in transfected mice and seems not to act as GTPase activating protein.	figure legend:2 C|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/04/04	2014/10/16	rogid:n2YsPUkQrzvaH0/De4h+/K5Q8rE9606	rogid:BJHzlKX2UFz3FpHeyuCsky/CrOU9606	intact-crc:5D056C020A07F9F6|rigid:ulrU7Nzyjjg5Z41nm5wGYMDnIjA	false	glutathione s tranferase tag:?-?	sufficient binding region:1-499|35s radiolabel:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P35125-3	uniprotkb:Q8N8A2	intact:EBI-954590|ensembl:ENSP00000461581	intact:EBI-1245329|uniprotkb:Q6P480|uniprotkb:Q86VL5|uniprotkb:Q8IZ72|uniprotkb:Q9UFA4|uniprotkb:Q53SL9|ensembl:ENSP00000282272	psi-mi:p35125-3(display_long)|uniprotkb:"210(ORF1)"(isoform synonym)|uniprotkb:oncTre210p(isoform synonym)|uniprotkb:USP6(gene name)|psi-mi:USP6(display_short)|uniprotkb:HRP1(gene name synonym)|uniprotkb:TRE2(gene name synonym)|uniprotkb:Deubiquitinating enzyme 6(gene name synonym)|uniprotkb:Proto-oncogene TRE-2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 6(gene name synonym)|uniprotkb:Ubiquitin thioesterase 6(gene name synonym)	psi-mi:anr44_human(display_long)|uniprotkb:ANKRD44(gene name)|psi-mi:ANKRD44(display_short)|uniprotkb:Ankyrin repeat domain-containing protein 44(gene name synonym)	psi-mi:"MI:0096"(pull down)	Dechamps et al. (2006)	pubmed:16555005	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1226034	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-954564(ubp6_human)|ensembl:ENSG00000129204(gene)|ensembl:ENST00000572949(transcript)	refseq:NP_001182073.1|refseq:NP_710181.2|refseq:XP_005247005.1|ensembl:ENSG00000065413(gene)|ensembl:ENST00000282272(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q8N8A2	-	isoform-comment:Was shown to be tumorigenic in transfected mice and seems not to act as GTPase activating protein.	-	figure legend:2 C|dataset:Cancer - Interactions investigated in the context of cancer	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/04/04	2014/10/16	rogid:BJHzlKX2UFz3FpHeyuCsky/CrOU9606	rogid:Vi+efSZ2F/weEJsGibCJCwhwlXs9606	intact-crc:D8CE8DAEAEEDE737|rigid:+yu4L50Olt+yxuzAA4+a0HQZ8Fo	false	35s radiolabel:?-?|sufficient binding region:1-499	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)	psi-mi:"MI:0821"(molecular weight estimation by autoradiography)
uniprotkb:P10916	uniprotkb:P35125-3	intact:EBI-725770|uniprotkb:Q16123|ensembl:ENSP00000228841	intact:EBI-954590|ensembl:ENSP00000461581	psi-mi:mlrv_human(display_long)|uniprotkb:MYL2(gene name)|psi-mi:MYL2(display_short)|uniprotkb:Cardiac myosin light chain 2(gene name synonym)|uniprotkb:MLC2(gene name synonym)|uniprotkb:Myosin light chain 2, slow skeletal/ventricular muscle isoform(gene name synonym)|uniprotkb:Ventricular myosin light chain 2(gene name synonym)	psi-mi:p35125-3(display_long)|uniprotkb:"210(ORF1)"(isoform synonym)|uniprotkb:oncTre210p(isoform synonym)|uniprotkb:USP6(gene name)|psi-mi:USP6(display_short)|uniprotkb:HRP1(gene name synonym)|uniprotkb:TRE2(gene name synonym)|uniprotkb:Deubiquitinating enzyme 6(gene name synonym)|uniprotkb:Proto-oncogene TRE-2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 6(gene name synonym)|uniprotkb:Ubiquitin thioesterase 6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Dechamps et al. (2006)	pubmed:16555005	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1226126	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000423.2|ensembl:ENSG00000111245(gene)|ensembl:ENST00000228841(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098735"(positive regulation of the force of heart contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:5TBY|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)	intact:EBI-954564(ubp6_human)|ensembl:ENSG00000129204(gene)|ensembl:ENST00000572949(transcript)	-	-	isoform-comment:Was shown to be tumorigenic in transfected mice and seems not to act as GTPase activating protein.	figure legend:3|delivery method:P10916; P35125-3 transfection|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/04/04	2014/10/16	rogid:n2YsPUkQrzvaH0/De4h+/K5Q8rE9606	rogid:BJHzlKX2UFz3FpHeyuCsky/CrOU9606	intact-crc:E74C4D0F8D485FF9|rigid:ulrU7Nzyjjg5Z41nm5wGYMDnIjA	false	myc tag:?-?	flag tag:?-?|sufficient binding region:1-499	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P35125-3	uniprotkb:Q8N8A2	intact:EBI-954590|ensembl:ENSP00000461581	intact:EBI-1245329|uniprotkb:Q6P480|uniprotkb:Q86VL5|uniprotkb:Q8IZ72|uniprotkb:Q9UFA4|uniprotkb:Q53SL9|ensembl:ENSP00000282272	psi-mi:p35125-3(display_long)|uniprotkb:"210(ORF1)"(isoform synonym)|uniprotkb:oncTre210p(isoform synonym)|uniprotkb:USP6(gene name)|psi-mi:USP6(display_short)|uniprotkb:HRP1(gene name synonym)|uniprotkb:TRE2(gene name synonym)|uniprotkb:Deubiquitinating enzyme 6(gene name synonym)|uniprotkb:Proto-oncogene TRE-2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 6(gene name synonym)|uniprotkb:Ubiquitin thioesterase 6(gene name synonym)	psi-mi:anr44_human(display_long)|uniprotkb:ANKRD44(gene name)|psi-mi:ANKRD44(display_short)|uniprotkb:Ankyrin repeat domain-containing protein 44(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Dechamps et al. (2006)	pubmed:16555005	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1226147	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-954564(ubp6_human)|ensembl:ENSG00000129204(gene)|ensembl:ENST00000572949(transcript)	refseq:NP_001182073.1|refseq:NP_710181.2|refseq:XP_005247005.1|ensembl:ENSG00000065413(gene)|ensembl:ENST00000282272(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q8N8A2	-	isoform-comment:Was shown to be tumorigenic in transfected mice and seems not to act as GTPase activating protein.	-	figure legend:3|delivery method:Q8N8A2; P35125-3 transfection|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/04/04	2014/10/16	rogid:BJHzlKX2UFz3FpHeyuCsky/CrOU9606	rogid:Vi+efSZ2F/weEJsGibCJCwhwlXs9606	intact-crc:BFD924039CCDE8A5|rigid:+yu4L50Olt+yxuzAA4+a0HQZ8Fo	false	flag tag:?-?|sufficient binding region:1-499	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P35125-3	uniprotkb:Q8N8A2	intact:EBI-954590|ensembl:ENSP00000461581	intact:EBI-1245329|uniprotkb:Q6P480|uniprotkb:Q86VL5|uniprotkb:Q8IZ72|uniprotkb:Q9UFA4|uniprotkb:Q53SL9|ensembl:ENSP00000282272	psi-mi:p35125-3(display_long)|uniprotkb:"210(ORF1)"(isoform synonym)|uniprotkb:oncTre210p(isoform synonym)|uniprotkb:USP6(gene name)|psi-mi:USP6(display_short)|uniprotkb:HRP1(gene name synonym)|uniprotkb:TRE2(gene name synonym)|uniprotkb:Deubiquitinating enzyme 6(gene name synonym)|uniprotkb:Proto-oncogene TRE-2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 6(gene name synonym)|uniprotkb:Ubiquitin thioesterase 6(gene name synonym)	psi-mi:anr44_human(display_long)|uniprotkb:ANKRD44(gene name)|psi-mi:ANKRD44(display_short)|uniprotkb:Ankyrin repeat domain-containing protein 44(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Dechamps et al. (2006)	pubmed:16555005	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1226172	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-954564(ubp6_human)|ensembl:ENSG00000129204(gene)|ensembl:ENST00000572949(transcript)	refseq:NP_001182073.1|refseq:NP_710181.2|refseq:XP_005247005.1|ensembl:ENSG00000065413(gene)|ensembl:ENST00000282272(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q8N8A2	-	isoform-comment:Was shown to be tumorigenic in transfected mice and seems not to act as GTPase activating protein.	-	figure legend:3|delivery method:Q8N8A2; P35125-3 transfection|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/04/04	2014/10/16	rogid:BJHzlKX2UFz3FpHeyuCsky/CrOU9606	rogid:Vi+efSZ2F/weEJsGibCJCwhwlXs9606	intact-crc:AEA60BD28F0ED014|rigid:+yu4L50Olt+yxuzAA4+a0HQZ8Fo	false	flag tag:?-?|sufficient binding region:1-499	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P35125-3	uniprotkb:P10916	intact:EBI-954590|ensembl:ENSP00000461581	intact:EBI-725770|uniprotkb:Q16123|ensembl:ENSP00000228841	psi-mi:p35125-3(display_long)|uniprotkb:"210(ORF1)"(isoform synonym)|uniprotkb:oncTre210p(isoform synonym)|uniprotkb:USP6(gene name)|psi-mi:USP6(display_short)|uniprotkb:HRP1(gene name synonym)|uniprotkb:TRE2(gene name synonym)|uniprotkb:Deubiquitinating enzyme 6(gene name synonym)|uniprotkb:Proto-oncogene TRE-2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 6(gene name synonym)|uniprotkb:Ubiquitin thioesterase 6(gene name synonym)	psi-mi:mlrv_human(display_long)|uniprotkb:MYL2(gene name)|psi-mi:MYL2(display_short)|uniprotkb:Cardiac myosin light chain 2(gene name synonym)|uniprotkb:MLC2(gene name synonym)|uniprotkb:Myosin light chain 2, slow skeletal/ventricular muscle isoform(gene name synonym)|uniprotkb:Ventricular myosin light chain 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Dechamps et al. (2006)	pubmed:16555005	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1226194	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-954564(ubp6_human)|ensembl:ENSG00000129204(gene)|ensembl:ENST00000572949(transcript)	refseq:NP_000423.2|ensembl:ENSG00000111245(gene)|ensembl:ENST00000228841(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098735"(positive regulation of the force of heart contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:5TBY|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)	-	isoform-comment:Was shown to be tumorigenic in transfected mice and seems not to act as GTPase activating protein.	-	figure legend:3|delivery method:P10916; P35125-3 transfection|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2007/04/04	2014/10/16	rogid:BJHzlKX2UFz3FpHeyuCsky/CrOU9606	rogid:n2YsPUkQrzvaH0/De4h+/K5Q8rE9606	intact-crc:68769D29AC4ECF37|rigid:ulrU7Nzyjjg5Z41nm5wGYMDnIjA	false	sufficient binding region:1-499|flag tag:?-?	myc tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P10916	uniprotkb:P35125-3	intact:EBI-725770|uniprotkb:Q16123|ensembl:ENSP00000228841	intact:EBI-954590|ensembl:ENSP00000461581	psi-mi:mlrv_human(display_long)|uniprotkb:MYL2(gene name)|psi-mi:MYL2(display_short)|uniprotkb:Cardiac myosin light chain 2(gene name synonym)|uniprotkb:MLC2(gene name synonym)|uniprotkb:Myosin light chain 2, slow skeletal/ventricular muscle isoform(gene name synonym)|uniprotkb:Ventricular myosin light chain 2(gene name synonym)	psi-mi:p35125-3(display_long)|uniprotkb:"210(ORF1)"(isoform synonym)|uniprotkb:oncTre210p(isoform synonym)|uniprotkb:USP6(gene name)|psi-mi:USP6(display_short)|uniprotkb:HRP1(gene name synonym)|uniprotkb:TRE2(gene name synonym)|uniprotkb:Deubiquitinating enzyme 6(gene name synonym)|uniprotkb:Proto-oncogene TRE-2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 6(gene name synonym)|uniprotkb:Ubiquitin thioesterase 6(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Dechamps et al. (2006)	pubmed:16555005	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1226220	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000423.2|ensembl:ENSG00000111245(gene)|ensembl:ENST00000228841(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098735"(positive regulation of the force of heart contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|rcsb pdb:5TBY|reactome:R-HSA-390522|go:"GO:0008307"(structural constituent of muscle)	intact:EBI-954564(ubp6_human)|ensembl:ENSG00000129204(gene)|ensembl:ENST00000572949(transcript)	go:"GO:0005886"(plasma membrane)	-	isoform-comment:Was shown to be tumorigenic in transfected mice and seems not to act as GTPase activating protein.	figure legend:4 D|comment:Tre-GAP expression appears to cause MYL2 to relocate to cell membrane, as in the absence of Tre-GAP MYL2 is distributed throughout the cell.|delivery method:P10916; P35125-3 transfection|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/04/04	2014/10/16	rogid:n2YsPUkQrzvaH0/De4h+/K5Q8rE9606	rogid:BJHzlKX2UFz3FpHeyuCsky/CrOU9606	intact-crc:E11C35E732D20866|rigid:ulrU7Nzyjjg5Z41nm5wGYMDnIjA	false	red fluorescent protein tag:?-?	green fluorescent protein tag:?-?|sufficient binding region:1-499	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35125-3	uniprotkb:Q8N8A2	intact:EBI-954590|ensembl:ENSP00000461581	intact:EBI-1245329|uniprotkb:Q6P480|uniprotkb:Q86VL5|uniprotkb:Q8IZ72|uniprotkb:Q9UFA4|uniprotkb:Q53SL9|ensembl:ENSP00000282272	psi-mi:p35125-3(display_long)|uniprotkb:"210(ORF1)"(isoform synonym)|uniprotkb:oncTre210p(isoform synonym)|uniprotkb:USP6(gene name)|psi-mi:USP6(display_short)|uniprotkb:HRP1(gene name synonym)|uniprotkb:TRE2(gene name synonym)|uniprotkb:Deubiquitinating enzyme 6(gene name synonym)|uniprotkb:Proto-oncogene TRE-2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 6(gene name synonym)|uniprotkb:Ubiquitin thioesterase 6(gene name synonym)	psi-mi:anr44_human(display_long)|uniprotkb:ANKRD44(gene name)|psi-mi:ANKRD44(display_short)|uniprotkb:Ankyrin repeat domain-containing protein 44(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Dechamps et al. (2006)	pubmed:16555005	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1226253	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-954564(ubp6_human)|ensembl:ENSG00000129204(gene)|ensembl:ENST00000572949(transcript)	refseq:NP_001182073.1|refseq:NP_710181.2|refseq:XP_005247005.1|ensembl:ENSG00000065413(gene)|ensembl:ENST00000282272(transcript)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:Q8N8A2	go:"GO:0005886"(plasma membrane)	isoform-comment:Was shown to be tumorigenic in transfected mice and seems not to act as GTPase activating protein.	-	figure legend:4 E|comment:Tre-GAP expression appears to cause LOC91526 to relocate to cell membrane, as in the absence of Tre-GAP LOC91526 is distributed throughout the cell.|delivery method:Q8N8A2; P35125-3 transfection|dataset:Cancer - Interactions investigated in the context of cancer	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/04/04	2014/10/16	rogid:BJHzlKX2UFz3FpHeyuCsky/CrOU9606	rogid:Vi+efSZ2F/weEJsGibCJCwhwlXs9606	intact-crc:397D07473C32A127|rigid:+yu4L50Olt+yxuzAA4+a0HQZ8Fo	false	green fluorescent protein tag:?-?|sufficient binding region:1-499	red fluorescent protein tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)