#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q13287 uniprotkb:O55170 intact:EBI-372942|uniprotkb:Q53TI8|intact:EBI-10174268|uniprotkb:Q8WTW2|uniprotkb:Q9BVE5|uniprotkb:B5BU69|ensembl:ENSP00000243346 intact:EBI-1185693|ensembl:ENSRNOP00000015283 psi-mi:nmi_human(display_long)|uniprotkb:NMI(gene name)|psi-mi:NMI(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym) psi-mi:sox10_rat(display_long)|uniprotkb:Sox10(gene name)|psi-mi:Sox10(display_short) psi-mi:"MI:0018"(two hybrid) Schlierf et al. (2005) pubmed:16214168 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1185703 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004679.2|refseq:XP_005246998.1|ensembl:ENSG00000123609(gene)|ensembl:ENST00000243346(transcript)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032687"(negative regulation of interferon-alpha production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033527|mint:Q13287|refseq:XP_016860736.1 rgd:3735|refseq:NP_062066.1|ensembl:ENSRNOG00000011305(gene)|ensembl:ENSRNOT00000015283(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014015"(positive regulation of gliogenesis)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0048469"(cell maturation)|go:"GO:0048484"(enteric nervous system development)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022151|interpro:IPR036910|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048709"(oligodendrocyte differentiation)|mint:O55170|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061138"(morphogenesis of a branching epithelium)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:XP_017450187.1 - - - - taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/01/19 2014/10/16 rogid:qOkzIuloaWW88apb9JH2DT/Bnuk9606 rogid:Hd/UiEz1qp9nrNUhB7fQABrM8/810116 intact-crc:0052A6DDC2BDFB59|rigid:oy3MrUZaW+hDxgf7uGRqljzTHf0 false sufficient binding region:75-307 sufficient binding region:133-203(IPR009071) - - psi-mi:"MI:0056"(full identification by DNA sequencing) psi-mi:"MI:0056"(full identification by DNA sequencing) uniprotkb:P56693 uniprotkb:Q13287 intact:EBI-1167533|uniprotkb:B4DV62|uniprotkb:Q6FHW7|ensembl:ENSP00000354130|ensembl:ENSP00000380093 intact:EBI-372942|uniprotkb:Q53TI8|intact:EBI-10174268|uniprotkb:Q8WTW2|uniprotkb:Q9BVE5|uniprotkb:B5BU69|ensembl:ENSP00000243346 psi-mi:sox10_human(display_long)|uniprotkb:SOX10(gene name)|psi-mi:SOX10(display_short) psi-mi:nmi_human(display_long)|uniprotkb:NMI(gene name)|psi-mi:NMI(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Schlierf et al. (2005) pubmed:16214168 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1185717 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008872.1|ensembl:ENSG00000100146(gene)|ensembl:ENST00000360880(transcript)|ensembl:ENST00000396884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014015"(positive regulation of gliogenesis)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048469"(cell maturation)|go:"GO:0048484"(enteric nervous system development)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061138"(morphogenesis of a branching epithelium)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022151|interpro:IPR036910|reactome:R-HSA-9619665 refseq:NP_004679.2|refseq:XP_005246998.1|ensembl:ENSG00000123609(gene)|ensembl:ENST00000243346(transcript)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032687"(negative regulation of interferon-alpha production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033527|mint:Q13287|refseq:XP_016860736.1 - - - figure legend:1b taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/01/19 2014/10/16 rogid:AKrWYlZirtToU/lVD3TerSaJyWY9606 rogid:qOkzIuloaWW88apb9JH2DT/Bnuk9606 intact-crc:47CFD7418C89DB06|rigid:qwAr9lODXZA9526NxYx8+mFxCBU false - myc tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P56693 uniprotkb:Q13287 intact:EBI-1167533|uniprotkb:B4DV62|uniprotkb:Q6FHW7|ensembl:ENSP00000354130|ensembl:ENSP00000380093 intact:EBI-372942|uniprotkb:Q53TI8|intact:EBI-10174268|uniprotkb:Q8WTW2|uniprotkb:Q9BVE5|uniprotkb:B5BU69|ensembl:ENSP00000243346 psi-mi:sox10_human(display_long)|uniprotkb:SOX10(gene name)|psi-mi:SOX10(display_short) psi-mi:nmi_human(display_long)|uniprotkb:NMI(gene name)|psi-mi:NMI(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Schlierf et al. (2005) pubmed:16214168 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1185730 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008872.1|ensembl:ENSG00000100146(gene)|ensembl:ENST00000360880(transcript)|ensembl:ENST00000396884(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014015"(positive regulation of gliogenesis)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048469"(cell maturation)|go:"GO:0048484"(enteric nervous system development)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0061138"(morphogenesis of a branching epithelium)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022151|interpro:IPR036910|reactome:R-HSA-9619665 refseq:NP_004679.2|refseq:XP_005246998.1|ensembl:ENSG00000123609(gene)|ensembl:ENST00000243346(transcript)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032687"(negative regulation of interferon-alpha production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033527|mint:Q13287|refseq:XP_016860736.1 - - - figure legend:1c taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/01/19 2014/10/16 rogid:AKrWYlZirtToU/lVD3TerSaJyWY9606 rogid:qOkzIuloaWW88apb9JH2DT/Bnuk9606 intact-crc:42912A597495E3BA|rigid:qwAr9lODXZA9526NxYx8+mFxCBU false sufficient binding region:1-203|myc tag:n-n ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q13287 uniprotkb:O55170 intact:EBI-372942|uniprotkb:Q53TI8|intact:EBI-10174268|uniprotkb:Q8WTW2|uniprotkb:Q9BVE5|uniprotkb:B5BU69|ensembl:ENSP00000243346 intact:EBI-1185693|ensembl:ENSRNOP00000015283 psi-mi:nmi_human(display_long)|uniprotkb:NMI(gene name)|psi-mi:NMI(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym) psi-mi:sox10_rat(display_long)|uniprotkb:Sox10(gene name)|psi-mi:Sox10(display_short) psi-mi:"MI:0096"(pull down) Schlierf et al. (2005) pubmed:16214168 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1185768 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004679.2|refseq:XP_005246998.1|ensembl:ENSG00000123609(gene)|ensembl:ENST00000243346(transcript)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032687"(negative regulation of interferon-alpha production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033527|mint:Q13287|refseq:XP_016860736.1 rgd:3735|refseq:NP_062066.1|ensembl:ENSRNOG00000011305(gene)|ensembl:ENSRNOT00000015283(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014015"(positive regulation of gliogenesis)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0048469"(cell maturation)|go:"GO:0048484"(enteric nervous system development)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022151|interpro:IPR036910|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048709"(oligodendrocyte differentiation)|mint:O55170|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061138"(morphogenesis of a branching epithelium)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:XP_017450187.1 - - - figure legend:2b taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/01/19 2014/10/16 rogid:qOkzIuloaWW88apb9JH2DT/Bnuk9606 rogid:Hd/UiEz1qp9nrNUhB7fQABrM8/810116 intact-crc:5DF15A045755106F|rigid:oy3MrUZaW+hDxgf7uGRqljzTHf0 false sufficient binding region:135-307,1-200 sufficient binding region:133-203(IPR009071)|glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q13287 uniprotkb:O55170 intact:EBI-372942|uniprotkb:Q53TI8|intact:EBI-10174268|uniprotkb:Q8WTW2|uniprotkb:Q9BVE5|uniprotkb:B5BU69|ensembl:ENSP00000243346 intact:EBI-1185693|ensembl:ENSRNOP00000015283 psi-mi:nmi_human(display_long)|uniprotkb:NMI(gene name)|psi-mi:NMI(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym) psi-mi:sox10_rat(display_long)|uniprotkb:Sox10(gene name)|psi-mi:Sox10(display_short) psi-mi:"MI:0096"(pull down) Schlierf et al. (2005) pubmed:16214168 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1185814 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004679.2|refseq:XP_005246998.1|ensembl:ENSG00000123609(gene)|ensembl:ENST00000243346(transcript)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032687"(negative regulation of interferon-alpha production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033527|mint:Q13287|refseq:XP_016860736.1 rgd:3735|refseq:NP_062066.1|ensembl:ENSRNOG00000011305(gene)|ensembl:ENSRNOT00000015283(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014015"(positive regulation of gliogenesis)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0048469"(cell maturation)|go:"GO:0048484"(enteric nervous system development)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022151|interpro:IPR036910|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048709"(oligodendrocyte differentiation)|mint:O55170|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061138"(morphogenesis of a branching epithelium)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:XP_017450187.1 - - - figure legend:2b taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2007/01/19 2014/10/16 rogid:qOkzIuloaWW88apb9JH2DT/Bnuk9606 rogid:Hd/UiEz1qp9nrNUhB7fQABrM8/810116 intact-crc:4998BC6F7D9F27D9|rigid:oy3MrUZaW+hDxgf7uGRqljzTHf0 false sufficient binding region:135-200|green fluorescent protein tag:?-? sufficient binding region:133-203(IPR009071)|glutathione s tranferase tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q13287 uniprotkb:O55170 intact:EBI-372942|uniprotkb:Q53TI8|intact:EBI-10174268|uniprotkb:Q8WTW2|uniprotkb:Q9BVE5|uniprotkb:B5BU69|ensembl:ENSP00000243346 intact:EBI-1185693|ensembl:ENSRNOP00000015283 psi-mi:nmi_human(display_long)|uniprotkb:NMI(gene name)|psi-mi:NMI(display_short)|uniprotkb:N-myc and STAT interactor(gene name synonym) psi-mi:sox10_rat(display_long)|uniprotkb:Sox10(gene name)|psi-mi:Sox10(display_short) psi-mi:"MI:0663"(confocal microscopy) Schlierf et al. (2005) pubmed:16214168 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-1185854 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004679.2|refseq:XP_005246998.1|ensembl:ENSG00000123609(gene)|ensembl:ENST00000243346(transcript)|go:"GO:0002281"(macrophage activation involved in immune response)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0032687"(negative regulation of interferon-alpha production)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902524"(positive regulation of protein K48-linked ubiquitination)|interpro:IPR009909(Nmi/IFP 35)|interpro:IPR009938(Interferon-induced 35 kDa, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033527|mint:Q13287|refseq:XP_016860736.1 rgd:3735|refseq:NP_062066.1|ensembl:ENSRNOG00000011305(gene)|ensembl:ENSRNOT00000015283(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010626"(negative regulation of Schwann cell proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014015"(positive regulation of gliogenesis)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030154"(cell differentiation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048468"(cell development)|go:"GO:0048469"(cell maturation)|go:"GO:0048484"(enteric nervous system development)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022151|interpro:IPR036910|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0048589"(developmental growth)|go:"GO:0048709"(oligodendrocyte differentiation)|mint:O55170|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061138"(morphogenesis of a branching epithelium)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|refseq:XP_017450187.1 go:"GO:0005634"(nucleus) - - figure legend:4d taxid:10116(rat-c6)|taxid:10116(Rattus norvegicus) - 2007/01/19 2014/10/16 rogid:qOkzIuloaWW88apb9JH2DT/Bnuk9606 rogid:Hd/UiEz1qp9nrNUhB7fQABrM8/810116 intact-crc:571CAA83035B61D1|rigid:oy3MrUZaW+hDxgf7uGRqljzTHf0 false myc tag:n-n - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)