#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q15436	uniprotkb:Q07002	intact:EBI-81088|uniprotkb:B2R5P4|uniprotkb:Q8NE16|ensembl:ENSP00000306881|uniprotkb:B3KXI2	intact:EBI-746238|uniprotkb:Q5VXQ2|uniprotkb:Q96F90|uniprotkb:Q6V3A2|uniprotkb:Q6V3A3|ensembl:ENSP00000353176|ensembl:ENSP00000399082	psi-mi:sc23a_human(display_long)|uniprotkb:SEC23A(gene name)|psi-mi:SEC23A(display_short)|uniprotkb:SEC23-related protein A(gene name synonym)	psi-mi:cdk18_human(display_long)|uniprotkb:CDK18(gene name)|psi-mi:CDK18(display_short)|uniprotkb:PCTAIRE-motif protein kinase 3(gene name synonym)|uniprotkb:PCTK3(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-3(gene name synonym)|uniprotkb:Cell division protein kinase 18(gene name synonym)|uniprotkb:PCTAIRE3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Palmer et al. (2005)	pubmed:16091426	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1212236	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006355.2|ensembl:ENST00000307712(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|ensembl:ENSG00000100934(gene)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15436|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:2YRC|rcsb pdb:2YRD|rcsb pdb:3EFO|rcsb pdb:3EG9|rcsb pdb:3EGD|rcsb pdb:3EGX|rcsb pdb:5KYN|rcsb pdb:5KYU|rcsb pdb:5KYW|rcsb pdb:5KYX|rcsb pdb:5KYY|rcsb pdb:5VNE|rcsb pdb:5VNF|rcsb pdb:5VNG|rcsb pdb:5VNH|rcsb pdb:5VNI|interpro:IPR036180|rcsb pdb:5VNJ|rcsb pdb:5VNK|rcsb pdb:5VNL|rcsb pdb:5VNM|rcsb pdb:5VNN|rcsb pdb:5VNO|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|reactome:R-HSA-1655829	refseq:NP_002587.2|refseq:NP_997667.1|refseq:NP_997668.1|ensembl:ENSG00000117266(gene)|ensembl:ENST00000360066(transcript)|ensembl:ENST00000429964(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q07002	-	-	-	-	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/03/08	2018/04/06	rogid:u1FCes02jPb3CGRj1aDkzpbSiuI9606	rogid:iTMOb7leFi1qGR6aa+R5MMtREOc9606	intact-crc:20D5A68BF562D379|rigid:kLPBVXz7yLz0sWjA7GNkG5k+oLo	false	-	sufficient binding region:91-242	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07002	uniprotkb:Q15436	intact:EBI-746238|uniprotkb:Q5VXQ2|uniprotkb:Q96F90|uniprotkb:Q6V3A2|uniprotkb:Q6V3A3|ensembl:ENSP00000353176|ensembl:ENSP00000399082	intact:EBI-81088|uniprotkb:B2R5P4|uniprotkb:Q8NE16|ensembl:ENSP00000306881|uniprotkb:B3KXI2	psi-mi:cdk18_human(display_long)|uniprotkb:CDK18(gene name)|psi-mi:CDK18(display_short)|uniprotkb:PCTAIRE-motif protein kinase 3(gene name synonym)|uniprotkb:PCTK3(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-3(gene name synonym)|uniprotkb:Cell division protein kinase 18(gene name synonym)|uniprotkb:PCTAIRE3(gene name synonym)	psi-mi:sc23a_human(display_long)|uniprotkb:SEC23A(gene name)|psi-mi:SEC23A(display_short)|uniprotkb:SEC23-related protein A(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Palmer et al. (2005)	pubmed:16091426	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1212248	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002587.2|refseq:NP_997667.1|refseq:NP_997668.1|ensembl:ENSG00000117266(gene)|ensembl:ENST00000360066(transcript)|ensembl:ENST00000429964(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q07002	refseq:NP_006355.2|ensembl:ENST00000307712(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|ensembl:ENSG00000100934(gene)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15436|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:2YRC|rcsb pdb:2YRD|rcsb pdb:3EFO|rcsb pdb:3EG9|rcsb pdb:3EGD|rcsb pdb:3EGX|rcsb pdb:5KYN|rcsb pdb:5KYU|rcsb pdb:5KYW|rcsb pdb:5KYX|rcsb pdb:5KYY|rcsb pdb:5VNE|rcsb pdb:5VNF|rcsb pdb:5VNG|rcsb pdb:5VNH|rcsb pdb:5VNI|interpro:IPR036180|rcsb pdb:5VNJ|rcsb pdb:5VNK|rcsb pdb:5VNL|rcsb pdb:5VNM|rcsb pdb:5VNN|rcsb pdb:5VNO|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|reactome:R-HSA-1655829	-	-	-	comment:The central region of PCTK3 shown to interact with SEC23A is common to all isoforms of PCTK3 known at time of publication. The interaction was not observed with full length PTCK3.|figure legend:Fig 1A, B, C	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/03/08	2018/04/06	rogid:iTMOb7leFi1qGR6aa+R5MMtREOc9606	rogid:u1FCes02jPb3CGRj1aDkzpbSiuI9606	intact-crc:5D696B66E454473E|rigid:kLPBVXz7yLz0sWjA7GNkG5k+oLo	false	sufficient binding region:91-242	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O94855	uniprotkb:Q07002	intact:EBI-748817|intact:EBI-1212263|uniprotkb:Q8IYI7|ensembl:ENSP00000280551	intact:EBI-746238|uniprotkb:Q5VXQ2|uniprotkb:Q96F90|uniprotkb:Q6V3A2|uniprotkb:Q6V3A3|ensembl:ENSP00000353176|ensembl:ENSP00000399082	psi-mi:sc24d_human(display_long)|uniprotkb:KIAA0755(gene name synonym)|uniprotkb:SEC24D(gene name)|psi-mi:SEC24D(display_short)|uniprotkb:SEC24-related protein D(gene name synonym)	psi-mi:cdk18_human(display_long)|uniprotkb:CDK18(gene name)|psi-mi:CDK18(display_short)|uniprotkb:PCTAIRE-motif protein kinase 3(gene name synonym)|uniprotkb:PCTK3(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-3(gene name synonym)|uniprotkb:Cell division protein kinase 18(gene name synonym)|uniprotkb:PCTAIRE3(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Palmer et al. (2005)	pubmed:16091426	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1212256	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001304995.1|refseq:NP_055637.2|refseq:XP_005263436.1|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|mint:O94855|rcsb pdb:3EFO|rcsb pdb:3EG9|rcsb pdb:5KYU|rcsb pdb:5KYW|rcsb pdb:5KYX|rcsb pdb:5KYY|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|ensembl:ENSG00000150961(gene)|ensembl:ENST00000280551(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036175	refseq:NP_002587.2|refseq:NP_997667.1|refseq:NP_997668.1|ensembl:ENSG00000117266(gene)|ensembl:ENST00000360066(transcript)|ensembl:ENST00000429964(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q07002	-	-	-	comment:The interaction was observed to weaker than that between PCTK3 and SEC24A. The interaction was not observed with full length PTCK3.|figure legend:Fig 1A, B, C	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/03/08	2018/04/06	rogid:CuxIZAR5xQP4Kc0ucDYGZ+siB8w9606	rogid:iTMOb7leFi1qGR6aa+R5MMtREOc9606	intact-crc:CF59681B822E0501|rigid:eGMA0v+31peCw/Mka77Hh5Ha7d4	false	-	sufficient binding region:91-242	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q00536	uniprotkb:Q15436	intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751	intact:EBI-81088|uniprotkb:B2R5P4|uniprotkb:Q8NE16|ensembl:ENSP00000306881|uniprotkb:B3KXI2	psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym)	psi-mi:sc23a_human(display_long)|uniprotkb:SEC23A(gene name)|psi-mi:SEC23A(display_short)|uniprotkb:SEC23-related protein A(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Palmer et al. (2005)	pubmed:16091426	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1212281	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1	refseq:NP_006355.2|ensembl:ENST00000307712(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|ensembl:ENSG00000100934(gene)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15436|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:2YRC|rcsb pdb:2YRD|rcsb pdb:3EFO|rcsb pdb:3EG9|rcsb pdb:3EGD|rcsb pdb:3EGX|rcsb pdb:5KYN|rcsb pdb:5KYU|rcsb pdb:5KYW|rcsb pdb:5KYX|rcsb pdb:5KYY|rcsb pdb:5VNE|rcsb pdb:5VNF|rcsb pdb:5VNG|rcsb pdb:5VNH|rcsb pdb:5VNI|interpro:IPR036180|rcsb pdb:5VNJ|rcsb pdb:5VNK|rcsb pdb:5VNL|rcsb pdb:5VNM|rcsb pdb:5VNN|rcsb pdb:5VNO|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|reactome:R-HSA-1655829	-	-	-	comment:The interacting region of PCTK1 has been inferred by alignment to PCTK3. The interaction was not observed with full length PTCK3.|figure legend:Fig 1C	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/03/08	2014/10/16	rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606	rogid:u1FCes02jPb3CGRj1aDkzpbSiuI9606	intact-crc:F2471F9FF55DDFA2|rigid:uma5TfWCBYMBDfC+G+S1S2SLDwc	false	sufficient binding region:112-263	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O94855	uniprotkb:Q00536	intact:EBI-748817|intact:EBI-1212263|uniprotkb:Q8IYI7|ensembl:ENSP00000280551	intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751	psi-mi:sc24d_human(display_long)|uniprotkb:KIAA0755(gene name synonym)|uniprotkb:SEC24D(gene name)|psi-mi:SEC24D(display_short)|uniprotkb:SEC24-related protein D(gene name synonym)	psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Palmer et al. (2005)	pubmed:16091426	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1212289	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001304995.1|refseq:NP_055637.2|refseq:XP_005263436.1|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|mint:O94855|rcsb pdb:3EFO|rcsb pdb:3EG9|rcsb pdb:5KYU|rcsb pdb:5KYW|rcsb pdb:5KYX|rcsb pdb:5KYY|reactome:R-HSA-1655829|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|ensembl:ENSG00000150961(gene)|ensembl:ENST00000280551(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036175	refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1	-	-	-	comment:The interacting region of PCTK1 has been inferred by alignment to PCTK3. The interaction was not observed with full length PTCK1.|figure legend:Fig 1C	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2007/03/08	2014/10/16	rogid:CuxIZAR5xQP4Kc0ucDYGZ+siB8w9606	rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606	intact-crc:6E04536C4A4EB664|rigid:AJ6FV3PPfXVNK04rjHC6xc0ZsZk	false	-	sufficient binding region:112-263	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q15436	uniprotkb:Q00536	intact:EBI-81088|uniprotkb:B2R5P4|uniprotkb:Q8NE16|ensembl:ENSP00000306881|uniprotkb:B3KXI2	intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751	psi-mi:sc23a_human(display_long)|uniprotkb:SEC23A(gene name)|psi-mi:SEC23A(display_short)|uniprotkb:SEC23-related protein A(gene name synonym)	psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Palmer et al. (2005)	pubmed:16091426	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1212310	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006355.2|ensembl:ENST00000307712(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|ensembl:ENSG00000100934(gene)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15436|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:2YRC|rcsb pdb:2YRD|rcsb pdb:3EFO|rcsb pdb:3EG9|rcsb pdb:3EGD|rcsb pdb:3EGX|rcsb pdb:5KYN|rcsb pdb:5KYU|rcsb pdb:5KYW|rcsb pdb:5KYX|rcsb pdb:5KYY|rcsb pdb:5VNE|rcsb pdb:5VNF|rcsb pdb:5VNG|rcsb pdb:5VNH|rcsb pdb:5VNI|interpro:IPR036180|rcsb pdb:5VNJ|rcsb pdb:5VNK|rcsb pdb:5VNL|rcsb pdb:5VNM|rcsb pdb:5VNN|rcsb pdb:5VNO|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|reactome:R-HSA-1655829	refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1	-	-	-	figure legend:Fig 2	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2007/03/08	2014/10/16	rogid:u1FCes02jPb3CGRj1aDkzpbSiuI9606	rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606	intact-crc:F86118A20A37DF09|rigid:uma5TfWCBYMBDfC+G+S1S2SLDwc	false	flag tag:?-?	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q00536	uniprotkb:Q15436	intact:EBI-726261|uniprotkb:J3KQP7|uniprotkb:A8K280|intact:EBI-11086061|uniprotkb:B7Z7C8|uniprotkb:J3KN74|ensembl:ENSP00000349762|ensembl:ENSP00000429751	intact:EBI-81088|uniprotkb:B2R5P4|uniprotkb:Q8NE16|ensembl:ENSP00000306881|uniprotkb:B3KXI2	psi-mi:cdk16_human(display_long)|uniprotkb:PCTAIRE-motif protein kinase 1(gene name synonym)|uniprotkb:CDK16(gene name)|psi-mi:CDK16(display_short)|uniprotkb:PCTK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PCTAIRE-1(gene name synonym)|uniprotkb:Cell division protein kinase 16(gene name synonym)|uniprotkb:PCTAIRE1(gene name synonym)	psi-mi:sc23a_human(display_long)|uniprotkb:SEC23A(gene name)|psi-mi:SEC23A(display_short)|uniprotkb:SEC23-related protein A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Palmer et al. (2005)	pubmed:16091426	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1212330	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001163931.1|refseq:NP_006192.1|refseq:NP_148978.2|ensembl:ENSG00000102225(gene)|ensembl:ENST00000357227(transcript)|ensembl:ENST00000518022(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006887"(exocytosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0031175"(neuron projection development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0061178"(regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3MTL|rcsb pdb:5G6V|refseq:XP_016885059.1|refseq:XP_016885060.1|refseq:XP_016885061.1|refseq:XP_016885062.1	refseq:NP_006355.2|ensembl:ENST00000307712(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|ensembl:ENSG00000100934(gene)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15436|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:2YRC|rcsb pdb:2YRD|rcsb pdb:3EFO|rcsb pdb:3EG9|rcsb pdb:3EGD|rcsb pdb:3EGX|rcsb pdb:5KYN|rcsb pdb:5KYU|rcsb pdb:5KYW|rcsb pdb:5KYX|rcsb pdb:5KYY|rcsb pdb:5VNE|rcsb pdb:5VNF|rcsb pdb:5VNG|rcsb pdb:5VNH|rcsb pdb:5VNI|interpro:IPR036180|rcsb pdb:5VNJ|rcsb pdb:5VNK|rcsb pdb:5VNL|rcsb pdb:5VNM|rcsb pdb:5VNN|rcsb pdb:5VNO|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|reactome:R-HSA-1655829	-	-	-	figure legend:Fig 3B	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2007/03/08	2014/10/16	rogid:mfs9ttMAcIdCxUToO/+V02dBRkE9606	rogid:u1FCes02jPb3CGRj1aDkzpbSiuI9606	intact-crc:42B386CE8A596329|rigid:uma5TfWCBYMBDfC+G+S1S2SLDwc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:F1PBY2	uniprotkb:Q15436	intact:EBI-1212335|ensembl:ENSCAFP00000014825	intact:EBI-81088|uniprotkb:B2R5P4|uniprotkb:Q8NE16|ensembl:ENSP00000306881|uniprotkb:B3KXI2	psi-mi:f1pby2_canlf(display_long)|uniprotkb:CDK18(gene name)|psi-mi:CDK18(display_short)	psi-mi:sc23a_human(display_long)|uniprotkb:SEC23A(gene name)|psi-mi:SEC23A(display_short)|uniprotkb:SEC23-related protein A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Palmer et al. (2005)	pubmed:16091426	taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-1212344	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSCAFG00000010082(gene)|ensembl:ENSCAFT00000016029(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006468"(protein phosphorylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)	refseq:NP_006355.2|ensembl:ENST00000307712(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|ensembl:ENSG00000100934(gene)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036465|interpro:IPR037364|interpro:IPR037550|mint:Q15436|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:2YRC|rcsb pdb:2YRD|rcsb pdb:3EFO|rcsb pdb:3EG9|rcsb pdb:3EGD|rcsb pdb:3EGX|rcsb pdb:5KYN|rcsb pdb:5KYU|rcsb pdb:5KYW|rcsb pdb:5KYX|rcsb pdb:5KYY|rcsb pdb:5VNE|rcsb pdb:5VNF|rcsb pdb:5VNG|rcsb pdb:5VNH|rcsb pdb:5VNI|interpro:IPR036180|rcsb pdb:5VNJ|rcsb pdb:5VNK|rcsb pdb:5VNL|rcsb pdb:5VNM|rcsb pdb:5VNN|rcsb pdb:5VNO|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|reactome:R-HSA-1655829	-	-	-	figure legend:Fig 3C	taxid:9615(canlf-mdck)|taxid:9615("Canis familiaris (dog) kidney epithelial cells")	-	2007/03/08	2020/01/07	rogid:03WyaBYiDdLktTnkDvMsFzwhtaM9615	rogid:u1FCes02jPb3CGRj1aDkzpbSiuI9606	intact-crc:9A84B593E6DF946B|rigid:fqdHr53TEy3NXMA8sF30LVtRzc4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)