#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9C107 uniprotkb:P28040 intact:EBI-1203666|ensemblfungi:"SPAPB1E7.02c.1:pep" intact:EBI-455823|uniprotkb:Q9UTY1|ensemblfungi:"SPAC3H5.06c.1:pep" psi-mi:mcl1_schpo(display_long)|uniprotkb:mcl1(gene name)|psi-mi:mcl1(display_short)|uniprotkb:SPAPB1E7.02c(orf name)|uniprotkb:slr3(gene name synonym)|uniprotkb:DNA polymerase alpha accessory factor Mcl1(gene name synonym) psi-mi:dpoa_schpo(display_long)|uniprotkb:swi7(gene name synonym)|uniprotkb:SPAC3H5.06c(orf name)|uniprotkb:pol1(gene name)|psi-mi:pol1(display_short)|uniprotkb:DNA polymerase I(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsutsui et al. (2005) pubmed:15915339|imex:IM-19929 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1206155|imex:IM-19929-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_594128.1|interpro:IPR022100|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR024977|mint:Q9C107|ensemblfungi:SPAPB1E7.02c(gene)|ensemblfungi:SPAPB1E7.02c.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0061641"(CENP-A containing chromatin organization)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|interpro:IPR036322 refseq:NP_594186.1|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR024647|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|reactome:R-SPO-113501|reactome:R-SPO-68952|reactome:R-SPO-68962|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|interpro:IPR038256|interpro:IPR036397|interpro:IPR042087|ensemblfungi:SPAC3H5.06c(gene)|ensemblfungi:SPAC3H5.06c.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061806"(regulation of DNA recombination at centromere)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1902981"(synthesis of RNA primer involved in mitotic DNA replication)|interpro:IPR043502 - - - figure legend:Figure 5B|comment:There was strong interaction mediated by the C-terminal of Mcl1 and the N-terminal of Pol1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/02/22 2014/10/16 rogid:D3mV0rIaeqOhafHjCccHWnTNQgk284812 rogid:WaDX9srYNf0Ahsc0m2ket2FDCXo284812 intact-crc:C2F0AB10B60BAA8D|rigid:n0OqDRM5W4+f/5mKkmFVpMjlB0I false necessary binding region:420-815 necessary binding region:1-867 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q9C107 uniprotkb:P28040 intact:EBI-1203666|ensemblfungi:"SPAPB1E7.02c.1:pep" intact:EBI-455823|uniprotkb:Q9UTY1|ensemblfungi:"SPAC3H5.06c.1:pep" psi-mi:mcl1_schpo(display_long)|uniprotkb:mcl1(gene name)|psi-mi:mcl1(display_short)|uniprotkb:SPAPB1E7.02c(orf name)|uniprotkb:slr3(gene name synonym)|uniprotkb:DNA polymerase alpha accessory factor Mcl1(gene name synonym) psi-mi:dpoa_schpo(display_long)|uniprotkb:swi7(gene name synonym)|uniprotkb:SPAC3H5.06c(orf name)|uniprotkb:pol1(gene name)|psi-mi:pol1(display_short)|uniprotkb:DNA polymerase I(gene name synonym) psi-mi:"MI:0018"(two hybrid) Tsutsui et al. (2005) pubmed:15915339|imex:IM-19929 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1206184|imex:IM-19929-2 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_594128.1|interpro:IPR022100|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR024977|mint:Q9C107|ensemblfungi:SPAPB1E7.02c(gene)|ensemblfungi:SPAPB1E7.02c.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0061641"(CENP-A containing chromatin organization)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|interpro:IPR036322 refseq:NP_594186.1|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR024647|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|reactome:R-SPO-113501|reactome:R-SPO-68952|reactome:R-SPO-68962|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|interpro:IPR038256|interpro:IPR036397|interpro:IPR042087|ensemblfungi:SPAC3H5.06c(gene)|ensemblfungi:SPAC3H5.06c.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061806"(regulation of DNA recombination at centromere)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1902981"(synthesis of RNA primer involved in mitotic DNA replication)|interpro:IPR043502 - - - figure legend:Figure 5B|comment:There was strong interaction mediated by the C-terminal of Mcl1 and the N-terminal of Pol1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2007/02/22 2014/10/16 rogid:D3mV0rIaeqOhafHjCccHWnTNQgk284812 rogid:WaDX9srYNf0Ahsc0m2ket2FDCXo284812 intact-crc:22D5EC5415EEE4BE|rigid:n0OqDRM5W4+f/5mKkmFVpMjlB0I false necessary binding region:420-815 necessary binding region:1-867 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28040 uniprotkb:Q9C107 intact:EBI-455823|uniprotkb:Q9UTY1|ensemblfungi:"SPAC3H5.06c.1:pep" intact:EBI-1203666|ensemblfungi:"SPAPB1E7.02c.1:pep" psi-mi:dpoa_schpo(display_long)|uniprotkb:swi7(gene name synonym)|uniprotkb:SPAC3H5.06c(orf name)|uniprotkb:pol1(gene name)|psi-mi:pol1(display_short)|uniprotkb:DNA polymerase I(gene name synonym) psi-mi:mcl1_schpo(display_long)|uniprotkb:mcl1(gene name)|psi-mi:mcl1(display_short)|uniprotkb:SPAPB1E7.02c(orf name)|uniprotkb:slr3(gene name synonym)|uniprotkb:DNA polymerase alpha accessory factor Mcl1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsutsui et al. (2005) pubmed:15915339|imex:IM-19929 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1206208|imex:IM-19929-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_594186.1|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR024647|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|reactome:R-SPO-113501|reactome:R-SPO-68952|reactome:R-SPO-68962|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|interpro:IPR038256|interpro:IPR036397|interpro:IPR042087|ensemblfungi:SPAC3H5.06c(gene)|ensemblfungi:SPAC3H5.06c.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061806"(regulation of DNA recombination at centromere)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1902981"(synthesis of RNA primer involved in mitotic DNA replication)|interpro:IPR043502 refseq:NP_594128.1|interpro:IPR022100|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR024977|mint:Q9C107|ensemblfungi:SPAPB1E7.02c(gene)|ensemblfungi:SPAPB1E7.02c.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0061641"(CENP-A containing chromatin organization)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|interpro:IPR036322 - - - figure legend:Figure 5C|comment:There was strong interaction between Mcl1 and Pol1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2007/02/22 2014/10/16 rogid:WaDX9srYNf0Ahsc0m2ket2FDCXo284812 rogid:D3mV0rIaeqOhafHjCccHWnTNQgk284812 intact-crc:982050EF117600D9|rigid:n0OqDRM5W4+f/5mKkmFVpMjlB0I false myc tag:n-n ha tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P28040 uniprotkb:Q9C107 intact:EBI-455823|uniprotkb:Q9UTY1|ensemblfungi:"SPAC3H5.06c.1:pep" intact:EBI-1203666|ensemblfungi:"SPAPB1E7.02c.1:pep" psi-mi:dpoa_schpo(display_long)|uniprotkb:swi7(gene name synonym)|uniprotkb:SPAC3H5.06c(orf name)|uniprotkb:pol1(gene name)|psi-mi:pol1(display_short)|uniprotkb:DNA polymerase I(gene name synonym) psi-mi:mcl1_schpo(display_long)|uniprotkb:mcl1(gene name)|psi-mi:mcl1(display_short)|uniprotkb:SPAPB1E7.02c(orf name)|uniprotkb:slr3(gene name synonym)|uniprotkb:DNA polymerase alpha accessory factor Mcl1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tsutsui et al. (2005) pubmed:15915339|imex:IM-19929 taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") taxid:284812(schpo)|taxid:284812("Schizosaccharomyces pombe (strain ATCC 38366 / 972)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-1208357|imex:IM-19929-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_594186.1|interpro:IPR006172(DNA-directed DNA polymerase, family B)|interpro:IPR017964|interpro:IPR006133(DNA-directed DNA polymerase, family B, exonuclease)|interpro:IPR006134(DNA-directed DNA polymerase, family B, conserved region)|interpro:IPR024647|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR015088(Zinc finger, DNA-directed DNA polymerase, family B, alpha)|reactome:R-SPO-113501|reactome:R-SPO-68952|reactome:R-SPO-68962|reactome:R-SPO-69091|reactome:R-SPO-69166|reactome:R-SPO-69183|interpro:IPR038256|interpro:IPR036397|interpro:IPR042087|ensemblfungi:SPAC3H5.06c(gene)|ensemblfungi:SPAC3H5.06c.1(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003887"(DNA-directed DNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005658"("alpha DNA polymerase:primase complex")|go:"GO:0006272"(leading strand elongation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006279"(premeiotic DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007534"(gene conversion at mating-type locus)|go:"GO:0017076"(purine nucleotide binding)|go:"GO:0019103"(pyrimidine nucleotide binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061806"(regulation of DNA recombination at centromere)|go:"GO:0140445"(chromosome, telomeric repeat region)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1902981"(synthesis of RNA primer involved in mitotic DNA replication)|interpro:IPR043502 refseq:NP_594128.1|interpro:IPR022100|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR024977|mint:Q9C107|ensemblfungi:SPAPB1E7.02c(gene)|ensemblfungi:SPAPB1E7.02c.1(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0061641"(CENP-A containing chromatin organization)|go:"GO:1903461"(Okazaki fragment processing involved in mitotic DNA replication)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|interpro:IPR036322 - - - figure legend:Figure 5C|comment:There was strong interaction between Mcl1 and Pol1.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4896(schpm)|taxid:4896("Schizosaccharomyces pombe (fission yeast)") - 2007/02/22 2014/10/16 rogid:WaDX9srYNf0Ahsc0m2ket2FDCXo284812 rogid:D3mV0rIaeqOhafHjCccHWnTNQgk284812 intact-crc:7913979CB03627E4|rigid:n0OqDRM5W4+f/5mKkmFVpMjlB0I false myc tag:n-n ha tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)